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Bernard Malissen

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Antonio García-Blesa; Francisco J García-Cózar; Mikolaj Klossowicz; Carmen López-Osuna; Bernard Malissen; Mario Martínez-Florensa; Arkadiusz Miazek; Enrique Aguado
The membrane adaptor LAT is proteolytically cleaved following Fas engagement in a tyrosine phosphorylation-dependent fashion.
Maud Plantinga; Wendy Toussaint; Manon Vanheerswynghels; Leen Vanhoutte; Filipe Branco-Madeira; Kim Deswarte; Martin Guilliams; Hamida Hammad; Nigel Killeen; Bernard Malissen; Katrijn Neyt; Bart N Lambrecht
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen.
Simon Yona; Elazar Zelzer; Michal Breker; Martin Guilliams; David A Hume; Ki-Wook Kim; Bernard Malissen; Alexander Mildner; Alexander Misharin; Harris Perlman; Dalit Strauss-Ayali; Diana Varol; Sergey Viukov; Yochai Wolf; Steffen Jung
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis.

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2013: Antonio García-Blesa; Francisco J García-Cózar; Mikolaj Klossowicz; Carmen López-Osuna; Bernard Malissen; Mario Martínez-Florensa; Arkadiusz Miazek; Enrique Aguado
The membrane adaptor LAT is proteolytically cleaved following Fas engagement in a tyrosine phosphorylation-dependent fashion.
The Biochemical journal 2013;450(3):511-21.
2013: Maud Plantinga; Wendy Toussaint; Manon Vanheerswynghels; Leen Vanhoutte; Filipe Branco-Madeira; Kim Deswarte; Martin Guilliams; Hamida Hammad; Nigel Killeen; Bernard Malissen; Katrijn Neyt; Bart N Lambrecht
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen.
Immunity 2013;38(2):322-35.
2013: Simon Yona; Elazar Zelzer; Michal Breker; Martin Guilliams; David A Hume; Ki-Wook Kim; Bernard Malissen; Alexander Mildner; Alexander Misharin; Harris Perlman; Dalit Strauss-Ayali; Diana Varol; Sergey Viukov; Yochai Wolf; Steffen Jung
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis.
Immunity 2013;38(1):79-91.
2012: Samira Tamoutounour; C Janneke van der Woude; Andrea M Woltman; Calum C Bain; Dominique Bonnet; Béatrice de Bovis; Colin de Haar; Sandrine Henri; Hugues Lelouard; Bernard Malissen; Allan McI Mowat; Lionel F Poulin; Caetano Reis e Sousa; Yasmin Reyal; Dorine Sichien; Martin Guilliams
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis.
European journal of immunology 2012;42(12):3150-66.
2012: Richard Weiss; Josef Thalhamer; Esther E Weinberger; Doris Bach; Christof Boehler; Cornelia Hauser-Kronberger; Michael Hessenberger; Yogeshvar N Kalia; Sophie Kitzmüller; Wolf D Krautgartner; Bernard Malissen; Sandra Scheiblhofer
Transcutaneous vaccination via laser microporation.
Journal of controlled release : official journal of the Controlled Release Society 2012;162(2):391-9.
2012: Bernard Malissen
A voltage-gated sodium channel mediates positive selection of T cells.
Nature immunology 2012;13(9):810-2.
2012: Diana Ordoñez-Rueda; Sybille Sabrautzki; Weidong Zhao; Aurélie Malzac; David A Mancardi; Stéphane Méresse; Elodie Bertosio; Véronique Blanquet; Pierre Bruhns; Martin Hrabě de Angelis; Estelle Duprez; Pierre Grenot; Friederike Jönsson; Yinming Liang; Bernard Malissen; Marie Malissen
A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia.
European journal of immunology 2012;42(9):2395-408.
2012: Gwennaelle J Wathne; Chiara Zurzolo; adrien kissenpfennig; Bernard Malissen; Neil A Mabbott
Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin.
Journal of leukocyte biology 2012;91(5):817-28.
2012: Baptiste N Jaeger; Nizar Mahlaoui; Bernard Malissen; Marie Malissen; Emilie Narni-Mancinelli; Diana Ordoñez-Rueda; Eric Vivier; Marc Bajénoff; Vincent Barlogis; Blandine Beaupain; Christine Bellanné-Chantelot; Claire Bernat; Céline Cognet; jean donadieu; Aurore Fenis; Sophie Ugolini
Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis.
The Journal of experimental medicine 2012;209(3):565-80.
2012: Christelle Langlet; Hervé Luche; Bernard Malissen; Samira Tamoutounour; Laurence Ardouin; Claude Grégoire; Sandrine Henri; Martin Guilliams
CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):1751-60.
2012: Sylvie Guerder; Hervé Luche; Laurence Ardouin; Christophe Viret; Bernard Malissen
Differential processing of self-antigens by subsets of thymic stromal cells.
Current opinion in immunology 2012;24(1):99-104.
2012: Emilie Narni-Mancinelli; Frédéric Vely; Eric Vivier; Claire Bernat; Elodie Bertosio; Bruce Beutler; aude de gassart; Jordi Estellé; Aurore Fenis; Louis N Gastinel; Ivo G Gut; Marta Gut; Simon C Heath; Baptiste N Jaeger; Sam Kung; Sajid Mahmood; Bernard Malissen; Marie Malissen; Sophie Ugolini
Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses.
Science (New York, N.Y.) 2012;335(6066):344-8.
2012: Stéphane Chevrier; Céline Genton; Bernard Malissen; Marie Malissen; Hans Acha-Orbea
Dominant Role of CD80-CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LAT(Y136F) CD4(+) T Cells.
Frontiers in immunology 2012;3():27.
2011: Karine Crozat; Laurence Ardouin; Hiroaki Azukizawa; Bjarne Bogen; Even Fossum; Martin Guilliams; Sandrine Henri; Hervé Luche; Bernard Malissen; Samira Tamoutounour; Thien-Phong Vu Manh; Marc Dalod
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4411-5.
2011: Lisa Föhse; Reinhold Förster; Jan D Haas; Günter J Hämmerling; Christian Koenecke; Stella Lamprecht; Chun-Wei Lee; Cornelia Lindner; Bernard Malissen; Susanne Schmitz; Sebastian Suerbaum; Janine Suffner; Karsten Suhre; Benjamin Wahl; André Bleich; Immo Prinz
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells.
European journal of immunology 2011;41(11):3101-13.
2011: Ramkumar Sambasivan; Shahragim Tajbakhsh; Laetitia Van Wittenberghe; Roseline Yao; Barbara Gayraud-Morel; Hind Guenou; adrien kissenpfennig; Bernard Malissen; Andràs Paldi; Anne Galy
Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration.
Development (Cambridge, England) 2011;138(17):3647-56.
2011: Botond Z Igyártó; Judith Berman; Aleh Bobr; Brian T Edelson; Maryam Gerami-Nejad; Krystal Haley; Bernard Malissen; Daniela Ortner; Gerard Zurawski; Sandra M Zurawski; Daniel H Kaplan
Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses.
Immunity 2011;35(2):260-72.
2011: Hervé Luche; Laurence Ardouin; Florent Ginhoux; Sandrine Henri; Miriam Merad; Peter See; Pearline Teo; Bernard Malissen
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
European journal of immunology 2011;41(8):2165-75.
2011: Bernard Malissen; Didier Marguet
La(s)t but not least.
Nature immunology 2011;12(7):592-3.
2011: Christophe Viret; Stéphane Leung-Theung-Long; Laurent Serre; Camille Lamare; Dario A A Vignali; Bernard Malissen; Alice Carrier; Sylvie Guerder
Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.
The Journal of clinical investigation 2011;121(5):1810-21.
2011: Leona Gabryšová; Jillian R Christensen; Xuemei Wu; adrien kissenpfennig; Bernard Malissen; Anne O'Garra
Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells.
European journal of immunology 2011;41(5):1242-8.
2011: Angelika Stoecklinger; Tekalign D Eticha; Mehrnaz Mesdaghi; adrien kissenpfennig; Bernard Malissen; Josef Thalhamer; Peter Hammerl
Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH γ-1 class switching in response to gene gun vaccines.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(3):1377-83.
2011: Christophe Viret; Camille Lamare; Martine Guiraud; Nicolas Fazilleau; Agathe Bour; Bernard Malissen; Alice Carrier; Sylvie Guerder
Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire.
The Journal of experimental medicine 2011;208(1):3-11.
2011: Bruno Zaragoza; César Evaristo; adrien kissenpfennig; Valentina Libri; Bernard Malissen; Benedita Rocha; Antonio A Freitas; Afonso R M Almeida
Cell-to-cell interactions and signals involved in the reconstitution of peripheral CD8 T(CM) and T(EM) cell pools.
PloS one 2011;6(3):e17423.
2010: Cristel Archambaud; Suzana P Salcedo; Hugues Lelouard; Elisabeth Devilard; Beatrice de Bovis; Nico van Rooijen; Jean-Pierre Gorvel; Bernard Malissen
Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection.
European journal of immunology 2010;40(12):3458-71.
2010: Frano H Malinarich; Elena Grabski; Tim Worbs; Vijaykumar Chennupati; Jan D Haas; Susanne Schmitz; Enzo Candia; Rodrigo Quera; Bernard Malissen; Reinhold Förster; Marcela Hermoso; Immo Prinz
Constant TCR triggering suggests that the TCR expressed on intestinal intraepithelial γδ T cells is functional in vivo.
European journal of immunology 2010;40(12):3378-88.
2010: Vijaykumar Chennupati; Tim Worbs; Xiaosun Liu; Frano H Malinarich; Susanne Schmitz; Jan D Haas; Bernard Malissen; Reinhold Förster; Immo Prinz
Intra- and intercompartmental movement of gammadelta T cells: intestinal intraepithelial and peripheral gammadelta T cells represent exclusive nonoverlapping populations with distinct migration characteristics.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5160-8.
2010: Martin Guilliams; Sandrine Henri; Samira Tamoutounour; Laurence Ardouin; Isabelle Schwartz-Cornil; Marc Dalod; Bernard Malissen
From skin dendritic cells to a simplified classification of human and mouse dendritic cell subsets.
European journal of immunology 2010;40(8):2089-94.
2010: Romain Roncagalli; Michael Mingueneau; Claude Grégoire; Marie Malissen; Bernard Malissen
LAT signaling pathology: an "autoimmune" condition without T cell self-reactivity.
Trends in immunology 2010;31(7):253-9.
2010: Romain Roncagalli; Michael Mingueneau; Claude Grégoire; Christelle Langlet; Bernard Malissen; Marie Malissen
Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes.
Seminars in immunopathology 2010;32(2):117-25.
2010: Sandrine Henri; Martin Guilliams; Lionel Franz Poulin; Samira Tamoutounour; Laurence Ardouin; Marc Dalod; Bernard Malissen
Disentangling the complexity of the skin dendritic cell network.
Immunology and cell biology 2010;88(4):366-75.
2010: Martin Guilliams; Karine Crozat; Sandrine Henri; Samira Tamoutounour; Pierre Grenot; Elisabeth Devilard; Béatrice de Bovis; Lena Alexopoulou; Marc Dalod; Bernard Malissen
Skin-draining lymph nodes contain dermis-derived CD103(-) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells.
Blood 2010;115(10):1958-68.
2010: Karine Crozat; Rachel Guiton; Martin Guilliams; Sandrine Henri; Thomas Baranek; Isabelle Schwartz-Cornil; Bernard Malissen; Marc Dalod
Comparative genomics as a tool to reveal functional equivalences between human and mouse dendritic cell subsets.
Immunological reviews 2010;234(1):177-98.
2010: Alexandre Boissonnas; Alix Scholer-Dahirel; Virginie Simon-Blancal; Luigia Pace; Fabien Valet; adrien kissenpfennig; Tim D. Sparwasser; Bernard Malissen; Luc Fetler; Sebastian Amigorena
Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes.
Immunity 2010;32(2):266-78.
2010: Sandrine Henri; Lionel Franz Poulin; Samira Tamoutounour; Laurence Ardouin; Martin Guilliams; Béatrice de Bovis; Elisabeth Devilard; Christophe Viret; Hiroaki Azukizawa; adrien kissenpfennig; Bernard Malissen
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells.
The Journal of experimental medicine 2010;207(1):189-206.
2010: Hugues Lelouard; Sandrine Henri; Béatrice de Bovis; Bénédicte Mugnier; Alexandre Chollat-Namy; Bernard Malissen; Stéphane Méresse; Jean-Pierre Gorvel
Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme.
Gastroenterology 2010;138(1):173-84.e1-3.
2009: Christian Koenecke; Niklas Czeloth; Anja Bubke; Susanne Schmitz; adrien kissenpfennig; Bernard Malissen; Jochen Huehn; Arnold Ganser; Reinhold Förster; Immo Prinz
Alloantigen-specific de novo-induced Foxp3+ Treg revert in vivo and do not protect from experimental GVHD.
European journal of immunology 2009;39(11):3091-6.
2009: Arkadiusz Miazek; Kornelia Macha; Agnieszka Łaszkiewicz; adrien kissenpfennig; Bernard Malissen; Pawel Kisielow
Peripheral Thy1+ lymphocytes rearranging TCR-gammadelta genes in LAT-deficient mice.
European journal of immunology 2009;39(9):2596-605.
2009: Michael Mingueneau; Romain Roncagalli; Claude Grégoire; adrien kissenpfennig; Arkadiusz Miazek; Cristel Archambaud; Ying Wang; Pierre Perrin; Elodie Bertosio; Amandine Sansoni; Sylvie Richelme; Richard M Locksley; Enrique Aguado; Marie Malissen; Bernard Malissen
Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor.
Immunity 2009;31(2):197-208.
2009: Stéphane Chevrier; Céline Genton; Axel Kallies; Alexander Karnowski; Luc A Otten; Bernard Malissen; Marie Malissen; Marina Botto; Lynn M Corcoran; Stephen L Nutt; Hans Acha-Orbea
CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(10):3895-900.
2009: Cristel Archambaud; Amandine Sansoni; Michael Mingueneau; Elisabeth Devilard; Georges Delsol; Bernard Malissen; Marie Malissen
STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2680-9.
2009: Bernard Malissen
Deflecting a canonical antiviral T cell response.
Immunity 2009;30(2):169-71.
2009: Christian Koenecke; Vijaykumar Chennupati; Susanne Schmitz; Bernard Malissen; Reinhold Förster; Immo Prinz
In vivo application of mAb directed against the gammadelta TCR does not deplete but generates "invisible" gammadelta T cells.
European journal of immunology 2009;39(2):372-9.
2008: Inês Antunes; Mauro Tolaini; adrien kissenpfennig; Michihiro Iwashiro; Kagemasa Kuribayashi; Bernard Malissen; Kim Hasenkrug; George Kassiotis
Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology.
Immunity 2008;29(5):782-94.
2008: Julie Helft; Alexandra Jacquet; Nathalie T Joncker; Isabelle Grandjean; Guillaume Dorothée; adrien kissenpfennig; Bernard Malissen; Polly Matzinger; Olivier Lantz
Antigen-specific T-T interactions regulate CD4 T-cell expansion.
Blood 2008;112(4):1249-58.
2008: Bernard Malissen
CD3 ITAMs count!
Nature immunology 2008;9(6):583-4.
2008: Maria Apostolaki; Menelaos Manoloukos; Manolis Roulis; Marc-André Wurbel; Werner Müller; Werner Muller; Dimitris L Kontoyiannis; Bernard Malissen; george kollias
Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.
Gastroenterology 2008;134(7):2025-35.
2008: Michaël Mingueneau; Amandine Sansoni; Claude Grégoire; Romain Roncagalli; Enrique Aguado; Arthur Weiss; Marie Malissen; Bernard Malissen
The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes.
Nature immunology 2008;9(5):522-32.
2008: Marc Bartoli; Evelyne Gicquel; Laetitia Barrault; Tayebeh Soheili; Marie Malissen; Bernard Malissen; Nathalie Vincent-Lacaze; Norma Perez; Bjarne Udd; Olivier Danos; Isabelle Richard
Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.
Human molecular genetics 2008;17(9):1214-21.
2008: Sandrine Henri; Lionel Franz Poulin; Bernard Malissen
[The skin dermis host a new population of dendritic cells].
Médecine sciences : M/S 2008;24(4):346-7.
2008: Liangchun Wang; Laura S Bursch; adrien kissenpfennig; Bernard Malissen; Stephen C Jameson; Kristin A Hogquist
Langerin expressing cells promote skin immune responses under defined conditions.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4722-7.
2008: Sun-Young Chang; Hye-Ran Cha; Osamu Igarashi; Paul D Rennert; adrien kissenpfennig; Bernard Malissen; Masanobu Nanno; Hiroshi Kiyono; Mi-Na Kweon
Cutting edge: Langerin+ dendritic cells in the mesenteric lymph node set the stage for skin and gut immune system cross-talk.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4361-5.
2008: Karine Roget; Marie Malissen; Odile Malbec; Bernard Malissen; Marc Daëron
Non-T cell activation linker promotes mast cell survival by dampening the recruitment of SHIP1 by linker for activation of T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(6):3689-98.
2008: Patrizia Stoitzner; Laura K Green; Jae Y Jung; Kylie M Price; Christoph H Tripp; Bernard Malissen; adrien kissenpfennig; Ian F Hermans; franca ronchese
Tumor immunotherapy by epicutaneous immunization requires langerhans cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1991-8.
2008: Ying Wang; adrien kissenpfennig; Michael Mingueneau; Sylvie Richelme; Pierre Perrin; Stéphane Chevrier; Céline Genton; Bruno LUCAS; James P DiSanto; Hans Acha-Orbea; Bernard Malissen; Marie Malissen
Th2 lymphoproliferative disorder of LatY136F mutant mice unfolds independently of TCR-MHC engagement and is insensitive to the action of Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1565-75.
2007: Laura S Bursch; Liangchun Wang; Botond Igyarto; adrien kissenpfennig; Bernard Malissen; Daniel H Kaplan; Kristin A Hogquist
Identification of a novel population of Langerin+ dendritic cells.
The Journal of experimental medicine 2007;204(13):3147-56.
2007: Ginhoux Florent; Matthew P Collin; Milena Bogunovic; Michal Abel; Marylene Leboeuf; Julie Helft; Jordi C Ochando; adrien kissenpfennig; Bernard Malissen; Marcos Grisotto; Hans-Willem Snoeck; Gwendalyn J Randolph; Miriam Merad
Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state.
The Journal of experimental medicine 2007;204(13):3133-46.
2007: Lionel Franz Poulin; Sandrine Henri; Béatrice de Bovis; Elisabeth Devilard; adrien kissenpfennig; Bernard Malissen
The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells.
The Journal of experimental medicine 2007;204(13):3119-31.
2007: Claude Grégoire; Sarka Simova; Ying Wang; Amandine Sansoni; Sylvie Richelme; Anja Schmidt-Giese; Luca Simeoni; Pavla Angelisova; Dirk Reinhold; Burkhart Schraven; Vaclav Horejsi; Bernard Malissen; Marie Malissen
Deletion of the LIME adaptor protein minimally affects T and B cell development and function.
European journal of immunology 2007;37(11):3259-69.
2007: Dmitry M Gakamsky; Erwin Lewitzki; Ernst Grell; Xavier Saulquin; Bernard Malissen; Félix Montero-Julian; Marc Bonneville; Israel Pecht
Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(42):16639-44.
2007: Ashraf Ragab; Sonia Séverin; Marie-Pierre Gratacap; Enrique Aguado; Marie Malissen; Martine Jandrot-Perrus; Bernard Malissen; Jeannie Ragab-Thomas; Bernard Payrastre
Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation.
Blood 2007;110(7):2466-74.
2007: Catherine Mazza; Bernard Malissen
What guides MHC-restricted TCR recognition?
Seminars in immunology 2007;19(4):225-35.
2007: Angelika Stoecklinger; Ines Grieshuber; Sandra Scheiblhofer; Richard Weiss; Uwe Ritter; adrien kissenpfennig; Bernard Malissen; Nikolaus Romani; Franz Koch; Fatima Ferreira; Josef Thalhamer; Peter Hammerl
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):886-93.
2007: Marc-André Wurbel; Marie Malissen; Delphine Guy-Grand; Bernard Malissen; James J Campbell
Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7598-606.
2007: Charles Stewart; Thierry Walzer; Scott H Robbins; Bernard Malissen; Eric Vivier; Immo Prinz
Germ-line and rearranged Tcrd transcription distinguish bona fide NK cells and NK-like gammadelta T cells.
European journal of immunology 2007;37(6):1442-52.
2007: Sandrine Henri; Carole Siret; Patrick Machy; adrien kissenpfennig; Bernard Malissen; Lee Leserman
Mature DC from skin and skin-draining LN retain the ability to acquire and efficiently present targeted antigen.
European journal of immunology 2007;37(5):1184-93.
2007: Meike Wendland; Niklas Czeloth; Nicolas Mach; Bernard Malissen; Elisabeth Kremmer; Oliver Pabst; Reinhold Förster
CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6347-52.
2007: Catherine Mazza; Nathalie Auphan-Anezin; Claude Gregoire; Annick Guimezanes; Christine Kellenberger; Alain Roussel; Alice Kearney; Philip van der Merwe; Anne-Marie Schmitt-Verhulst; Bernard Malissen
How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?
The EMBO journal 2007;26(7):1972-83.
2007: Julien Gommeaux; Carla Cano; Stephane Garcia; Meritxell Gironella; Sylvia Pietri; Marcel Culcasi; Marie-Josèphe Pébusque; Bernard Malissen; Nelson J Dusetti; Juan L Iovanna; Alice Carrier
Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.
Molecular and cellular biology 2007;27(6):2215-28.
2007: Bernard Malissen; Ying Wang; Michael Mingueneau; Marie Malissen
Th2 lymphoproliferative disorders resulting from defective LAT signalosomes.
Novartis Foundation symposium 2007;281():93-100; discussion 100-2, 208-9.
2006: Immo Prinz; Amandine Sansoni; adrien kissenpfennig; Laurence Ardouin; Marie Malissen; Bernard Malissen
Visualization of the earliest steps of gammadelta T cell development in the adult thymus.
Nature immunology 2006;7(9):995-1003.
2006: Céline Genton; Ying Wang; Shozo Izui; Bernard Malissen; Georges Delsol; Gilbert J Fournié; Marie Malissen; Hans Acha-Orbea
The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(4):2285-93.
2006: Nathalie Auphan-Anezin; Catherine Mazza; Annick Guimezanes; Gregory A Barrett-Wilt; Félix Montero-Julian; Alain Roussel; Donald F Hunt; Bernard Malissen; Anne-Marie Schmitt-Verhulst
Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes.
European journal of immunology 2006;36(7):1856-66.
2006: Sabrina Chiesa; Michael Mingueneau; Nicolas Fuseri; Bernard Malissen; David H Raulet; Marie Malissen; Eric Vivier; Elena Tomasello
Multiplicity and plasticity of natural killer cell signaling pathways.
Blood 2006;107(6):2364-72.
2006: adrien kissenpfennig; Bernard Malissen
Langerhans cells--revisiting the paradigm using genetically engineered mice.
Trends in immunology 2006;27(3):132-9.
2006: Marc-André Wurbel; Bernard Malissen; James J Campbell
Complex regulation of CCR9 at multiple discrete stages of T cell development.
European journal of immunology 2006;36(1):73-81.
2005: Christine Kellenberger; Alain Roussel; Bernard Malissen
The H-2Kk MHC peptide-binding groove anchors the backbone of an octameric antigenic peptide in an unprecedented mode.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3819-25.
2005: Suzel Davanture; Julie Leignadier; Pascale Milani; Philippe Soubeyran; Bernard Malissen; Marie Malissen; Anne-Marie Schmitt-Verhulst; Claude Boyer
Selective defect in antigen-induced TCR internalization at the immune synapse of CD8 T cells bearing the ZAP-70(Y292F) mutation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3140-9.
2005: Immo Prinz; Claude Gregoire; Hans-Joachim Mollenkopf; Enrique Aguado; Ying Wang; Marie Malissen; Stefan H E Kaufmann; Bernard Malissen
The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):713-9.
2005: Immo Prinz; Mischo Kursar; Hans-Willi Mittrücker; Enrique Aguado; Ulrich Steinhoff; Stefan H E Kaufmann; Bernard Malissen
Autistic effector T cells in mice with a point mutation in the LAT adaptor fail to respond to Listeria monocytogenes infection.
International immunology 2005;17(7):951-7.
2005: Ying Wang; Ondrej Horvath; Andrea Hamm-Baarke; Mireille Richelme; Claude Grégoire; Rodolphe Guinamard; Vaclav Horejsi; Pavla Angelisova; Jiri Spicka; Burkhart Schraven; Bernard Malissen; Marie Malissen
Single and combined deletions of the NTAL/LAB and LAT adaptors minimally affect B-cell development and function.
Molecular and cellular biology 2005;25(11):4455-65.
2005: adrien kissenpfennig; Sandrine Henri; Bertrand Dubois; Corinne Laplace-Builhé; Pierre Perrin; Nikolaus Romani; Christoph H Tripp; Patrice Douillard; Lee Leserman; Dominique Kaiserlian; Sem Saeland; Jean Davoust; Bernard Malissen
Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.
Immunity 2005;22(5):643-54.
2005: Laurence Ardouin; Antonius G Rolink; Anne-Marie Mura; Julien Gommeaux; Fritz Melchers; Meinrad Busslinger; Marie Malissen; Bernard Malissen
Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells.
European journal of immunology 2005;35(3):977-86.
2005: Bernard Malissen; Enrique Aguado; Marie Malissen
Role of the LAT adaptor in T-cell development and Th2 differentiation.
Advances in immunology 2005;87():1-25.
2005: Eric Vivier; Bernard Malissen
Innate and adaptive immunity: specificities and signaling hierarchies revisited.
Nature immunology 2005;6(1):17-21.
2005: adrien kissenpfennig; Smina Aït-Yahia; Valérie Clair-Moninot; Hella Stössel; Edgar Badell; Yann Bordat; Joanne L Pooley; Thierry Lang; Eric Prina; Isabelle Coste; Olivia Gresser; Toufic Renno; Nathalie Winter; Geneviève Milon; Ken Shortman; Nikolaus Romani; Serge Lebecque; Bernard Malissen; Sem Saeland; Patrice Douillard
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Molecular and cellular biology 2005;25(1):88-99.
2004: Marcus Svensson; Bengt Johansson-Lindbom; Marc-André Wurbel; Bernard Malissen; Gabriel Márquez; William W Agace
Selective generation of gut-tropic T cells in gut-associated lymphoid tissues: requirement for GALT dendritic cells and adjuvant.
Annals of the New York Academy of Sciences 2004;1029():405-7.
2004: Petra Volná; Pavel Lebduska; Lubica Dráberová; Sárka Símová; Petr Heneberg; Michael Boubelík; Viktor Bugajev; Bernard Malissen; Bridget S Wilson; Václav Horejsí; Marie Malissen; Petr Dráber
Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL.
The Journal of experimental medicine 2004;200(8):1001-13.
2004: Odile Malbec; Marie Malissen; Isabelle Isnardi; Renaud Lesourne; Anne-Marie Mura; Wolf H Fridman; Bernard Malissen; Marc Daëron
Linker for activation of T cells integrates positive and negative signaling in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5086-94.
2004: Oliver Pabst; Lars Ohl; Meike Wendland; Marc-André Wurbel; Elisabeth Kremmer; Bernard Malissen; Reinhold Förster
Chemokine receptor CCR9 contributes to the localization of plasma cells to the small intestine.
The Journal of experimental medicine 2004;199(3):411-6.
2003: Bernard Malissen
Immunology. Switching off TCR signaling.
Science (New York, N.Y.) 2003;302(5648):1162-3.
2003: Bernard Malissen
Glimpses at TCR trans-species crossreactivity.
Immunity 2003;19(4):463-4.
2003: Selene Nuñez-Cruz; Enrique Aguado; Sylvie Richelme; Bruno Chetaille; Anne-Marie Mura; Mireille Richelme; Laurent Pouyet; Evelyne Jouvin-Marche; Luc Xerri; Bernard Malissen; Marie Malissen
LAT regulates gammadelta T cell homeostasis and differentiation.
Nature immunology 2003;4(10):999-1008.
2003: Richard Tomasini; Amina Azizi Samir; Alice Carrier; Daniel Isnardon; Barbara Cecchinelli; Silvia Soddu; Bernard Malissen; Jean-Charles Dagorn; Juan L Iovanna; Nelson J Dusetti
TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity.
The Journal of biological chemistry 2003;278(39):37722-9.
2003: Bengt Johansson-Lindbom; Marcus Svensson; Marc-André Wurbel; Bernard Malissen; Gabriel Márquez; William W Agace
Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant.
The Journal of experimental medicine 2003;198(6):963-9.
2003: Dominique Housset; Bernard Malissen
What do TCR-pMHC crystal structures teach us about MHC restriction and alloreactivity?
Trends in immunology 2003;24(8):429-37.
2003: Jean-Baptiste Reiser; Claudine Darnault; Claude Grégoire; Thomas Mosser; Gilbert Mazza; Alice Kearney; Philip van der Merwe; Juan C Fontecilla-Camps; Dominique Housset; Bernard Malissen
CDR3 loop flexibility contributes to the degeneracy of TCR recognition.
Nature immunology 2003;4(3):241-7.
2003: C Trumel; Monique Plantavid; S Lévy-Tolédano; Ashraf Ragab; J P Caen; Enrique Aguado; Bernard Malissen; Bernard Payrastre
Platelet aggregation induced by the C-terminal peptide of thrombospondin-1 requires the docking protein LAT but is largely independent of alphaIIb/beta3.
Journal of thrombosis and haemostasis : JTH 2003;1(2):320-9.
2003: Bernard Malissen
An evolutionary and structural perspective on T cell antigen receptor function.
Immunological reviews 2003;191():7-27.
2003: Arkadiusz Miazek; Bernard Malissen
Two genes, three messengers: hybrid transcript between a gene expressed at specific stages of T-cell and sperm maturation and an unrelated adjacent gene.
Immunogenetics 2003;54(10):681-92.
2002: Enrique Aguado; Sylvie Richelme; Selene Nuñez-Cruz; Arkadiusz Miazek; Anne-Marie Mura; Mireille Richelme; Xiao-Jun Guo; Danielle Sainty; Hai-Tao He; Bernard Malissen; Marie Malissen
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor.
Science (New York, N.Y.) 2002;296(5575):2036-40.
2002: Jean-Baptiste Reiser; Claude Grégoire; Claudine Darnault; Thomas Mosser; Annick Guimezanes; Anne-Marie Schmitt-Verhulst; Juan C Fontecilla-Camps; Gilbert Mazza; Bernard Malissen; Dominique Housset
A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex.
Immunity 2002;16(3):345-54.
2002: Vincenzo Di Bartolo; Marie Malissen; Evelyne Dufour; Emmanuel Sechet; Bernard Malissen; Oreste Acuto
Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.
European journal of immunology 2002;32(2):568-75.
2002: Jenny Valladeau; Valérie Clair-Moninot; Colette Dezutter-Dambuyant; Jean-Jacques Pin; adrien kissenpfennig; Marie-Genevieve Mattéi; Smina Ait-Yahia; Elizabeth E M Bates; Bernard Malissen; Franz Koch; François Fossiez; Nikolaus Romani; Serge Lebecque; Sem Saeland
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(2):782-92.
2001: A Arcaro; Claude Grégoire; Talitha Bakker; Lucia Baldi; M Jordan; L Goffin; Nicole Boucheron; Florian M Wurm; Philip van der Merwe; Bernard Malissen; Immanuel F Luescher
CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes.
The Journal of experimental medicine 2001;194(10):1485-95.
2001: Marc-André Wurbel; Marie Malissen; D Guy-Grand; E Meffre; M C Nussenzweig; Mireille Richelme; Alice Carrier; Bernard Malissen
Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of early T- and B-cell development and a reduction in T-cell receptor gammadelta(+) gut intraepithelial lymphocytes.
Blood 2001;98(9):2626-32.
2001: A Magnan; Vincenzo Di Bartolo; Anne-Marie Mura; Claude Boyer; Mireille Richelme; Y L Lin; A Roure; A Gillet; Cecile Arrieumerlou; Oreste Acuto; Bernard Malissen; Marie Malissen
T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
The Journal of experimental medicine 2001;194(4):491-505.
2000: Elizabeth E M Bates; adrien kissenpfennig; Catherine Péronne; Marie-Geneviève Mattei; François Fossiez; Bernard Malissen; Serge Lebecque
The mouse and human IGSF6 (DORA) genes map to the inflammatory bowel disease 1 locus and are embedded in an intron of a gene of unknown function.
Immunogenetics 2000;52(1-2):112-20.
2000: Jean-Baptiste Reiser; Claudine Darnault; Annick Guimezanes; Claude Grégoire; Thomas Mosser; Anne-Marie Schmitt-Verhulst; Juan C Fontecilla-Camps; Bernard Malissen; Dominique Housset; Gilbert Mazza
Crystal structure of a T cell receptor bound to an allogeneic MHC molecule.
Nature immunology 2000;1(4):291-7.
2000: Alice Carrier; Marc-André Wurbel; Marie-Geneviève Mattei; adrien kissenpfennig; Marie Malissen; Bernard Malissen
Chromosomal localization of two mouse genes encoding thymus-specific serine peptidase and thymus-expressed acidic protein.
Immunogenetics 2000;51(11):984-6.
2000: A Arcaro; Claude Grégoire; Nicole Boucheron; S Stotz; Ed Palmer; Bernard Malissen; Immanuel F Luescher
Essential role of CD8 palmitoylation in CD8 coreceptor function.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(4):2068-76.
2000: Marc-André Wurbel; J M Philippe; Catherine Nguyen; Geneviève Victorero; T Freeman; P Wooding; Arkadiusz Miazek; Marie-Geneviève Mattei; Marie Malissen; Bertrand R Jordan; Bernard Malissen; Alice Carrier; Philippe Naquet
The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9.
European journal of immunology 2000;30(1):262-71.
1999: Alice Carrier; Catherine Nguyen; Geneviève Victorero; Samuel Granjeaud; D Rocha; K Bernard; Arkadiusz Miazek; Pierre Ferrier; Marie Malissen; Philippe Naquet; Bernard Malissen; Bertrand R Jordan
Differential gene expression in CD3epsilon- and RAG1-deficient thymuses: definition of a set of genes potentially involved in thymocyte maturation.
Immunogenetics 1999;50(5-6):255-70.
1999: Bernard Malissen
Dancing the immunological two-step.
Science (New York, N.Y.) 1999;285(5425):207-8.
1999: G Mazza; Dominique Housset; C Piras; Claude Grégoire; Juan C Fontecilla-Camps; Bernard Malissen
Structural features of the interaction between an anti-clonotypic antibody and its cognate T-cell antigen receptor.
Journal of molecular biology 1999;287(4):773-80.
1999: Laurence Ardouin; Claude Boyer; A Gillet; J Trucy; Anne-Marie Bernard; Jacques Nunès; Jérôme Delon; Alain Trautmann; Hai-Tao He; Bernard Malissen; Marie Malissen
Crippling of CD3-zeta ITAMs does not impair T cell receptor signaling.
Immunity 1999;10(4):409-20.
1999: B Kessler; Olivier Michielin; C L Blanchard; Irina Apostolou; Christiane Delarbre; Gabriel Gachelin; Claude Grégoire; Bernard Malissen; Jean-Charles Cerottini; Florian M Wurm; M Karplus; Immanuel F Luescher
T cell recognition of hapten. Anatomy of T cell receptor binding of a H-2kd-associated photoreactive peptide derivative.
The Journal of biological chemistry 1999;274(6):3622-31.
1999: Bernard Malissen; Laurence Ardouin; S Y Lin; A Gillet; Marie Malissen
Function of the CD3 subunits of the pre-TCR and TCR complexes during T cell development.
Advances in immunology 1999;72():103-48.
1998: Jérôme Delon; C Grégoire; Bernard Malissen; Sylvie Darche; Fabrice Lemaître; Philippe Kourilsky; Jean-Pierre Abastado; Alain Trautmann
CD8 expression allows T cell signaling by monomeric peptide-MHC complexes.
Immunity 1998;9(4):467-73.
1998: Bernard Malissen
Translating affinity into response.
Science (New York, N.Y.) 1998;281(5376):528-9.
1998: G Mazza; Dominique Housset; C Piras; Claude Gregoire; S Y Lin; Juan C Fontecilla-Camps; Bernard Malissen
Glimpses at the recognition of peptide/MHC complexes by T-cell antigen receptors.
Immunological reviews 1998;163():187-96.
1998: Laurence Ardouin; J Ismaili; Bernard Malissen; Marie Malissen
The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci.
The Journal of experimental medicine 1998;187(1):105-16.
1997: Marie Malissen; P Pereira; D J Gerber; Bernard Malissen; J P DiSanto
The common cytokine receptor gamma chain controls survival of gamma/delta T cells.
The Journal of experimental medicine 1997;186(8):1277-85.
1997: Dominique Housset; Gilbert Mazza; Claude Grégoire; C Piras; Bernard Malissen; Juan C Fontecilla-Camps
The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain.
The EMBO journal 1997;16(14):4205-16.
1997: S Y Lin; Laurence Ardouin; A Gillet; Marie Malissen; Bernard Malissen
The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex.
The Journal of experimental medicine 1997;185(4):707-15.
1996: V Renard; Jérôme Delon; Immanuel F Luescher; Bernard Malissen; Eric Vivier; Alain Trautmann
The CD8 beta polypeptide is required for the recognition of an altered peptide ligand as an agonist.
European journal of immunology 1996;26(12):2999-3007.
1996: V Renard; P Romero; Eric Vivier; Bernard Malissen; Immanuel F Luescher
CD8 beta increases CD8 coreceptor function and participation in TCR-ligand binding.
The Journal of experimental medicine 1996;184(6):2439-44.
1996: Claude Grégoire; Bernard Malissen; G Mazza
Characterization of T cell receptor single-chain Fv fragments secreted by myeloma cells.
European journal of immunology 1996;26(10):2410-6.
1996: Claude Grégoire; S Y Lin; G Mazza; N Rebai; Immanuel F Luescher; Bernard Malissen
Covalent assembly of a soluble T cell receptor-peptide-major histocompatibility class I complex.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):7184-9.
1996: Bernard Malissen; Marie Malissen
Functions of TCR and pre-TCR subunits: lessons from gene ablation.
Current opinion in immunology 1996;8(3):383-93.
1995: Y Tanaka; Laurence Ardouin; A Gillet; S Y Lin; A Magnan; Bernard Malissen; Marie Malissen
Early T-cell development in CD3-deficient mice.
Immunological reviews 1995;148():171-99.
1995: Marie Malissen; A Gillet; Laurence Ardouin; G Bouvier; J Trucy; Pierre Ferrier; Eric Vivier; Bernard Malissen
Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene.
The EMBO journal 1995;14(19):4641-53.
1995: Bernard Malissen; G Ku; M Hermans; Eric Vivier; Marie Malissen
Genetic dissection of the transducing subunits of the T-cell antigen receptor.
Annals of the New York Academy of Sciences 1995;766():173-81.
1995: V Renard; Laurence Ardouin; Marie Malissen; Geneviève Milon; Mai Lebastard; A Gillet; Bernard Malissen; Eric Vivier
Normal development and function of natural killer cells in CD3 epsilon delta 5/delta 5 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(16):7545-9.
1995: F Vignaux; Eric Vivier; Bernard Malissen; V Depraetere; S Nagata; Pierre Golstein
TCR/CD3 coupling to Fas-based cytotoxicity.
The Journal of experimental medicine 1995;181(2):781-6.
1995: Immanuel F Luescher; Eric Vivier; A Layer; J Mahiou; F Godeau; Bernard Malissen; Pedro Romero
CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes.
Nature 1995;373(6512):353-6.
1995: R Paolini; V Renard; Eric Vivier; K Ochiai; M H Jouvin; Bernard Malissen; Jean-Pierre Kinet
Different roles for the Fc epsilon RI gamma chain as a function of the receptor context.
The Journal of experimental medicine 1995;181(1):247-55.
1994: E Donnadieu; Alain Trautmann; Marie Malissen; J Trucy; Bernard Malissen; Eric Vivier
Reconstitution of CD3 zeta coupling to calcium mobilization via genetic complementation.
The Journal of biological chemistry 1994;269(52):32828-34.
1994: T Crompton; M Moore; H Robson MacDonald; Bernard Malissen
Double-negative thymocyte subsets in CD3 zeta chain-deficient mice: absence of HSA+CD44-CD25- cells.
European journal of immunology 1994;24(8):1903-7.
1994: N Auphan; J Curnow; Annick Guimezanes; C Langlet; Bernard Malissen; Andrew L Mellor; Anne-Marie Schmitt-Verhulst
The degree of CD8 dependence of cytolytic T cell precursors is determined by the nature of the T cell receptor (TCR) and influences negative selection in TCR-transgenic mice.
European journal of immunology 1994;24(7):1572-7.
1994: Maria Bellio; Yu-Chun Lone; O de la Calle-Martin; Bernard Malissen; Jean-Pierre Abastado; Philippe Kourilsky
The V beta complementarity determining region 1 of a major histocompatibility complex (MHC) class I-restricted T cell receptor is involved in the recognition of peptide/MHC I and superantigen/MHC II complex.
The Journal of experimental medicine 1994;179(4):1087-97.
1994: D Choquet; G Ku; S Cassard; Bernard Malissen; Henri Korn; Wolf H Fridman; Christian Bonnerot
Different patterns of calcium signaling triggered through two components of the B lymphocyte antigen receptor.
The Journal of biological chemistry 1994;269(9):6491-7.
1994: Anne_Marit Sponaas; P D Tomlinson; J Antoniou; N Auphan; C Langlet; Bernard Malissen; Anne-Marie Schmitt-Verhulst; Andrew L Mellor
Induction of tolerance to self MHC class I molecules expressed under the control of milk protein or beta-globin gene promoters.
International immunology 1994;6(2):277-87.
1994: G Ku; Bernard Malissen; M G Mattei
Chromosomal location of the Syk and ZAP-70 tyrosine kinase genes in mice and humans.
Immunogenetics 1994;40(4):300-2.
1994: A M Wegener; Bernard Malissen
Analysis of the (YXXL/I)2 signalling motifs found in the cytoplasmic segment of the mouse CD3-zeta chain.
Advances in experimental medicine and biology 1994;365():45-51.
1993: P Beaufils; D Choquet; R Z Mamoun; Bernard Malissen
The (YXXL/I)2 signalling motif found in the cytoplasmic segments of the bovine leukaemia virus envelope protein and Epstein-Barr virus latent membrane protein 2A can elicit early and late lymphocyte activation events.
The EMBO journal 1993;12(13):5105-12.
1993: M H Hermans; Bernard Malissen
The cytoplasmic tail of the T cell receptor zeta chain is dispensable for antigen-mediated T cell activation.
European journal of immunology 1993;23(9):2257-62.
1993: Bernard Malissen; Anne-Marie Schmitt-Verhulst
Transmembrane signalling through the T-cell-receptor-CD3 complex.
Current opinion in immunology 1993;5(3):324-33.
1993: A Hoeveler; Bernard Malissen
The cysteine residues in the cytoplasmic tail of CD8 alpha are required for its coreceptor function.
Molecular immunology 1993;30(8):755-64.
1993: Bernard Malissen; A M Wegener; A Hoeveler; D Marguet
Molecular dissection of the T-cell receptor/CD3 complex.
Immunology series 1993;59():29-40.
1992: N Auphan; A Jézo-Brémond; G Schönrich; Günter J Hämmerling; Bernd Arnold; Bernard Malissen; Anne-Marie Schmitt-Verhulst
Threshold tolerance in H-2Kb-specific TCR transgenic mice expressing mutant H-2Kb: conversion of helper-independent to helper-dependent CTL.
International immunology 1992;4(12):1419-28.
1992: M Knobloch; G Schönrich; Johannes Schenkel; Marie Malissen; Bernard Malissen; Anne-Marie Schmitt-Verhulst; Günter J Hämmerling; Bernd Arnold
T cell activation and thymic tolerance induction require different adhesion intensities of the CD8 co-receptor.
International immunology 1992;4(10):1169-74.
1992: Jean-Laurent Casanova; Jean-Charles Cerottini; M Matthes; A Necker; H Gournier; C Barra; C Widmann; H Robson MacDonald; F Lemonnier; Bernard Malissen; J L Maryanski
H-2-restricted cytolytic T lymphocytes specific for HLA display T cell receptors of limited diversity.
The Journal of experimental medicine 1992;176(2):439-47.
1992: Marie Malissen; J Trucy; Evelyne Jouvin-Marche; Pierre-André Cazenave; Roland Scollay; Bernard Malissen
Regulation of TCR alpha and beta gene allelic exclusion during T-cell development.
Immunology today 1992;13(8):315-22.
1992: G Schönrich; Frank Momburg; Marie Malissen; Anne-Marie Schmitt-Verhulst; Bernard Malissen; Günter J Hämmerling; Bernd Arnold
Distinct mechanisms of extrathymic T cell tolerance due to differential expression of self antigen.
International immunology 1992;4(5):581-90.
1992: N Auphan; G Schönrich; Marie Malissen; M Barad; Günter J Hämmerling; Bernd Arnold; Bernard Malissen; Anne-Marie Schmitt-Verhulst
Influence of antigen density on degree of clonal deletion in T cell receptor transgenic mice.
International immunology 1992;4(4):541-7.
1992: Immanuel F Luescher; J A Lóez; Bernard Malissen; Jean-Charles Cerottini
Interaction of antigenic peptides with MHC class I molecules on living cells studied by photoaffinity labeling.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(4):1003-11.
1992: Michel Buferne; F Luton; François Letourneur; A Hoeveler; D Couez; M Barad; Bernard Malissen; Anne-Marie Schmitt-Verhulst; Claude Boyer
Role of CD3 delta in surface expression of the TCR/CD3 complex and in activation for killing analyzed with a CD3 delta-negative cytotoxic T lymphocyte variant.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(3):657-64.
1992: Hanspeter Pircher; N Rebaï; M Groettrup; Claude Grégoire; D E Speiser; M P Happ; E Palmer; Rolf M Zinkernagel; Hans Hengartner; Bernard Malissen
Preferential positive selection of V alpha 2+ CD8+ T cells in mouse strains expressing both H-2k and T cell receptor V alpha a haplotypes: determination with a V alpha 2-specific monoclonal antibody.
European journal of immunology 1992;22(2):399-404.
1992: A M Wegener; François Letourneur; A Hoeveler; T Brocker; F Luton; Bernard Malissen
The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.
Cell 1992;68(1):83-95.
1991: A Necker; N Rebaï; M Matthes; Evelyne Jouvin-Marche; Pierre-André Cazenave; P Swarnworawong; E Palmer; H Robson MacDonald; Bernard Malissen
Monoclonal antibodies raised against engineered soluble mouse T cell receptors and specific for V alpha 8-, V beta 2- or V beta 10-bearing T cells.
European journal of immunology 1991;21(12):3035-40.
1991: Claude Grégoire; N Rebaï; F Schweisguth; A Necker; G Mazza; N Auphan; A Millward; Anne-Marie Schmitt-Verhulst; Bernard Malissen
Engineered secreted T-cell receptor alpha beta heterodimers.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):8077-81.
1991: Günter J Hämmerling; G Schönrich; Frank Momburg; N Auphan; Marie Malissen; Bernard Malissen; Anne-Marie Schmitt-Verhulst; Bernd Arnold
Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen.
Immunological reviews 1991;122():47-67.
1991: D Couez; Marie Malissen; Michel Buferne; Anne-Marie Schmitt-Verhulst; Bernard Malissen
Each of the two productive T cell receptor alpha-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an alpha chain which can contribute to the constitution of a surface-expressed alpha beta dimer.
International immunology 1991;3(7):719-29.
1991: Günter J Hämmerling; G Schönrich; Frank Momburg; Marie Malissen; Anne-Marie Schmitt-Verhulst; Bernard Malissen; Bernd Arnold
Distinct mechanisms of peripheral tolerance in transgenic mice.
Research in immunology 1991;142(5-6):417-20.
1991: G Schönrich; U Kalinke; Frank Momburg; Marie Malissen; Anne-Marie Schmitt-Verhulst; Bernard Malissen; Günter J Hämmerling; Bernd Arnold
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.
Cell 1991;65(2):293-304.
1991: Dominique Emilie; M Matthes; Claude Grégoire; François Letourneur; A M Wegener; J F Nicolas; Bernard Malissen
Fluorescence-based monitoring of interleukin-2 gene expression.
Immunological reviews 1991;119():95-103.
1990: Evelyne Jouvin-Marche; I Hue; Patrice N Marche; C Liebe-Gris; J P Marolleau; Bernard Malissen; Pierre-André Cazenave; Marie Malissen
Genomic organization of the mouse T cell receptor V alpha family.
The EMBO journal 1990;9(7):2141-50.
1990: I Hue; J Trucy; C McCoy; D Couez; Bernard Malissen; Marie Malissen
A novel type of aberrant T cell receptor alpha-chain gene rearrangement. Implications for allelic exclusion and the V-J recombination process.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(11):4410-9.
1990: François Letourneur; J Gabert; Pierre Cosson; D Blanc; Jean Davoust; Bernard Malissen
A signaling role for the cytoplasmic segment of the CD8 alpha chain detected under limiting stimulatory conditions.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(6):2339-43.
1989: François Letourneur; Bernard Malissen
Derivation of a T cell hybridoma variant deprived of functional T cell receptor alpha and beta chain transcripts reveals a nonfunctional alpha-mRNA of BW5147 origin.
European journal of immunology 1989;19(12):2269-74.
1989: Claude Boyer; N Auphan; J Gabert; D Blanc; Bernard Malissen; Anne-Marie Schmitt-Verhulst
Comparison of phosphorylation and internalization of the antigen receptor/CD3 complex, CD8, and class I MHC-encoded proteins on T cells. Role of intracytoplasmic domains analyzed with hybrid CD8/class I molecules.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(6):1905-14.
1989: Dominique Emilie; Michel Peuchmaur; M Barad; H Jouin; M C Maillot; D Couez; J F Nicolas; Bernard Malissen
Visualizing interleukin 2 gene expression at the single cell level.
European journal of immunology 1989;19(9):1619-24.
1989: François Letourneur; M G Mattei; Bernard Malissen
The mouse CD3-gamma, -delta, and -epsilon genes reside within 50 kilobases on chromosome 9, whereas CD3-zeta maps to chromosome 1, band H.
Immunogenetics 1989;29(4):265-8.
1988: Marie Malissen; J Trucy; François Letourneur; N Rebaï; D E Dunn; F W Fitch; L Hood; Bernard Malissen
A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition.
Cell 1988;55(1):49-59.
1988: N Rebaï; François Letourneur; N Shastri; S Marchetto; M Pierres; Bernard Malissen
Structure-function analysis of Ia molecules: in-phase insertion mutagenesis of the amino-terminal domain of the E beta k polypeptide chain.
Biochimie 1988;70(7):927-35.
1988: D Blanc; C Bron; J Gabert; François Letourneur; H Robson MacDonald; Bernard Malissen
Gene transfer of the Ly-3 chain gene of the mouse CD8 molecular complex: co-transfer with the Ly-2 polypeptide gene results in detectable cell surface expression of the Ly-3 antigenic determinants.
European journal of immunology 1988;18(4):613-9.
1987: J Gabert; C Langlet; Rose Zamoyska; Jane R Parnes; Anne-Marie Schmitt-Verhulst; Bernard Malissen
Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes.
Cell 1987;50(4):545-54.
1986: Marie Malissen; C McCoy; D Blanc; J Trucy; C Devaux; A M Schmitt-Verhulst; F Fitch; L Hood; Bernard Malissen
Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements.
Nature 1986;319(6048):28-33.