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Simon Mallal

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Yuichi Yagita; Tomohiro Akahoshi; Yasuo Ariumi; Zabrina L Brumme; Jonathan M Carlson; Takayuki Chikata; Yuko Fukunaga; Hiroyuki Gatanaga; Kazutaka Honda; Mina John; Ryo Kanda; Yuka Kawashima; Kimiko Kuroki; Nozomi Kuse; Katsumi Maenaka; Simon Mallal; Haruki Matsubara; Hayato Murakoshi; Shinichi Oka; Toyoyuki Ose; Nico Pfeifer; Masafumi Takiguchi
Distinct HIV-1 escape patterns selected by cytotoxic T cells with identical epitope specificity.
Elizabeth J Phillips; Simon Mallal
HLA-B*5701 and flucloxacillin associated drug-induced liver disease.
Susan Herrmann; Noel B Hyland; Christophe Lalanne; Simon Mallal; Elizabeth McKinnon; David Nolan; Olivier Chassany; Martin Duracinsky
HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection.

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All Publications

2013: Yuichi Yagita; Tomohiro Akahoshi; Yasuo Ariumi; Zabrina L Brumme; Jonathan M Carlson; Takayuki Chikata; Yuko Fukunaga; Hiroyuki Gatanaga; Kazutaka Honda; Mina John; Ryo Kanda; Yuka Kawashima; Kimiko Kuroki; Nozomi Kuse; Katsumi Maenaka; Simon Mallal; Haruki Matsubara; Hayato Murakoshi; Shinichi Oka; Toyoyuki Ose; Nico Pfeifer; Masafumi Takiguchi
Distinct HIV-1 escape patterns selected by cytotoxic T cells with identical epitope specificity.
Journal of virology 2013;87(4):2253-63.
2013: Elizabeth J Phillips; Simon Mallal
HLA-B*5701 and flucloxacillin associated drug-induced liver disease.
AIDS (London, England) 2013;27(3):491-2.
2013: Susan Herrmann; Noel B Hyland; Christophe Lalanne; Simon Mallal; Elizabeth McKinnon; David Nolan; Olivier Chassany; Martin Duracinsky
HIV-related stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection.
Health and quality of life outcomes 2013;11():56.
2012: Jonathan M Carlson; Mary Carrington; Celia K S Chui; Laura A Cotton; Charles E Deziel; P Richard Harrigan; Richard Haubrich; David Heckerman; Mina John; David J H F Knapp; Anh Q Le; Jennifer Listgarten; Simon Mallal; Eric Martin; George Nelson; Nico Pfeifer; Sharon A Riddler; Richard Apps; Mark Alan Brockman; Chanson J Brumme; Zabrina L Brumme
Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.
Journal of virology 2012;86(24):13202-16.
2012: Yuri A Pompeu; Jon D Stewart; Simon Mallal; Bjoern Peters; Elizabeth Phillips; David A Ostrov
The structural basis of HLA-associated drug hypersensitivity syndromes.
Immunological reviews 2012;250(1):158-66.
2012: Susan Herrmann; Mina John; Michaela Lucas; Simon Mallal; Silvana Gaudieri; Joan Wardrop; David Nolan
The impact of visa status and Medicare eligibility on people diagnosed with HIV in Western Australia: a qualitative report.
Sexual health 2012;9(5):407-13.
2012: Rebecca Pavlos; Simon Mallal; Elizabeth Phillips
HLA and pharmacogenetics of drug hypersensitivity.
Pharmacogenomics 2012;13(11):1285-306.
2012: David A Ostrov; Soren Buus; Cesar Augusto F de Oliveira; A Michelle English; Barry J Grant; Howard M Grey; Mikkel Harndahl; Donald F Hunt; Jean Jakoncic; Shun Lu; Andrew Lucas; Simon Mallal; Hu Mei; Carla Oseroff; Elizabeth Phillips; Yuri A Pompeu; Alessandro Sette; Jeffrey Shabanowitz; Leming Shi; John Sidney; Scott Southwood; Amanda Wriston; Lun Yang; Bjoern Peters
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(25):9959-64.
2012: Mark Alan Brockman; Chanson J Brumme; Christian Brander; Jonathan M Carlson; Peter K Cheung; Denis R Chopera; Nicole Frahm; P Richard Harrigan; David Heckerman; Heiko Jessen; Mina John; Anthony D Kelleher; Anh Q Le; Simon Mallal; Tristan J Markle; Martin Markowitz; Eric Martin; Rachel McGovern; Alex Olvera; Eric Rosenberg; Jorge Sanchez; Jennifer Sela; Bruce D Walker; Zabrina L Brumme
Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity.
Journal of virology 2012;86(12):6913-23.
2012: Susan E Herrmann; Mina John; Michaela Lucas; Simon Mallal; Elizabeth J McKinnon; Leah J Williams; David A Nolan
Use of alcohol, nicotine and other drugs in the Western Australian HIV Cohort study.
Sexual health 2012;9(2):199-201.
2012: Niamh M Keane; Tanya Krishnan; Rebecca Laird; Simon Mallal; Steven G Roberts; Monika Tschochner; Coral-Ann Almeida; Jonathan M Carlson; Abha Chopra; Emma Demaine; David Heckerman; Ian James; Mina John
High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection.
Immunology and cell biology 2012;90(2):224-34.
2011: Vijayaprakash Suppiah; Martin Weltman; Maria Lorena Abate; Golo Ahlenstiel; Nicola J Armstrong; Margaret Bassendine; Thomas Berg; Pierre-Yves Bochud; David R Booth; Gregory J Dore; David Dunn; Silvana Gaudieri; Jacob George; Emma Hammond; Margaret Hellard; William L Irving; Simon Mallal; Gail Matthews; Tobias Müller; Jacob Nattermann; Francesco Negro; Kate S O'Connor; Elizabeth Powell; Stephen Riordan; David Anthony Sheridan; Antonina Smedile; Ulrich Spengler; Graeme J Stewart
IL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional study.
PLoS medicine 2011;8(9):e1001092.
2011: Coral-Ann Almeida; Corine Bronke; Jonathan Carlson; Abha Chopra; David W Haas; Richard Haubrich; David Heckerman; Carl Kadie; Niamh M Keane; Simon Mallal; Elizabeth J McKinnon; Sharon A Riddler; Steven G Roberts; Mina John
Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA-adapted variant epitopes.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(5):2502-13.
2011: Tao Dong; Silvana Gaudieri; Ian James; Mina John; Ning Li; Wenhui Lun; Simon Mallal; Yu Mao; Andrew McMichael; Yanchun Peng; Wen Yan Qu; Tim Rostron; Hao Wu; Ke Yi Xu; Xiaoning Xu; Huiping Yan; Yonghong Zhang; Marie-Eve Blais; Xinyue Chen; Sarah L Rowland-Jones
Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China.
Blood 2011;118(1):98-106.
2011: Lyudmila Kostenko; A Lucas; K Lynch; Simon Mallal; Mandvi Bharadwaj; K Chen; B Foley; Rhonda Holdsworth; F Hudson; Lars Kjer-Nielsen; J Nguyen; I Nicholson; Jamie Rossjohn; Brian D Tait; A H B Wu; James McCluskey
Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity.
Tissue antigens 2011;78(1):11-20.
2011: Tomer Hertz; David Nolan; Ian James; Mina John; Silvana Gaudieri; Elizabeth Phillips; Jim C Huang; Gonzalo Riadi; Simon Mallal; Nebojsa Jojic
Mapping the landscape of host-pathogen coevolution: HLA class I binding and its relationship with evolutionary conservation in human and viral proteins.
Journal of virology 2011;85(3):1310-21.
2011: Katja Pfafferott; Silvana Gaudieri; Axel Ulsenheimer; Ian James; Malte Heeg; David Nolan; Mina John; Andri Rauch; Simon Mallal; Andrew Lucas; Paul Klenerman; Helmut M Diepolder; Michaela Lucas
Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity.
PloS one 2011;6(2):e16797.
2010: Yukie Iwabu; Masanobu Kinomoto; Masashi Tatsumi; Hideaki Fujita; Mari Shimura; Yoshitaka Tanaka; Yukihito Ishizaka; David Nolan; Simon Mallal; Tetsutaro Sata; Kenzo Tokunaga
Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes.
The Journal of biological chemistry 2010;285(46):35350-8.
2010: Coral-Ann M Almeida; Steven G Roberts; Rebecca Laird; Elizabeth McKinnon; Imran Ahmad; Niamh M Keane; Abha Chopra; Carl Kadie; David Heckerman; Simon Mallal; Mina John
Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses.
Vaccine 2010;28(37):6052-7.
2010: Elizabeth J Phillips; Simon Mallal
Pharmacogenetics of drug hypersensitivity.
Pharmacogenomics 2010;11(7):973-87.
2010: Mina John; David Heckerman; Ian James; Lawrence Park; Jonathan M Carlson; Abha Chopra; Silvana Gaudieri; David Nolan; David W Haas; Sharon A Riddler; Richard Haubrich; Simon Mallal
Adaptive interactions between HLA and HIV-1: highly divergent selection imposed by HLA class I molecules with common supertype motifs.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(8):4368-77.
2009: Andri Rauch; Ian James; Katja Pfafferott; David Nolan; Paul Klenerman; Wendy Cheng; Lindsay Mollison; Geoff McCaughan; Nick Shackel; Gary P Jeffrey; Ross Baker; Elizabeth Freitas; Isla Humphreys; Hansjakob Furrer; Huldrych F Günthard; Bernard Hirschel; Simon Mallal; Mina John; Michaela Lucas; Eleanor Barnes; Silvana Gaudieri
Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure.
Hepatology (Baltimore, Md.) 2009;50(4):1017-29.
2009: Coral-Ann M Almeida; Steven G Roberts; Rebecca Laird; Elizabeth J McKinnon; Imran Ahmed; Katja Pfafferott; Joanne Turley; Niamh M Keane; Andrew Lucas; Ben Rushton; Abha Chopra; Simon Mallal; Mina John
Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses.
Journal of immunological methods 2009;344(1):1-5.
2009: Silvana Gaudieri; Andri Rauch; Katja Pfafferott; Eleanor Barnes; Wendy Cheng; Geoff McCaughan; Nick Shackel; Gary P Jeffrey; Lindsay Mollison; Ross Baker; Hansjakob Furrer; Huldrych F Günthard; Elizabeth Freitas; Isla Humphreys; Paul Klenerman; Simon Mallal; Ian James; Stuart Roberts; David Nolan; Michaela Lucas
Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy.
Hepatology (Baltimore, Md.) 2009;49(4):1069-82.
2009: Toshiyuki Miura; Chanson J Brumme; Mark Alan Brockman; Zabrina L Brumme; Florencia Pereyra; Brian L Block; Alicja Trocha; Mina John; Simon Mallal; P Richard Harrigan; Bruce D Walker
HLA-associated viral mutations are common in human immunodeficiency virus type 1 elite controllers.
Journal of virology 2009;83(7):3407-12.
2009: Monika Tschochner; Abha Chopra; Tanya M Maiden; Imran F Ahmad; Ian James; Hansjakob Furrer; Huldrych F Günthard; Simon Mallal; Andri Rauch; Mina John
Effects of HIV type-1 immune selection on susceptability to integrase inhibitor resistance.
Antiviral therapy 2009;14(7):953-64.
2009: Zabrina L Brumme; Mina John; Jonathan M Carlson; Chanson J Brumme; Dennison Chan; Mark Alan Brockman; Luke C Swenson; Iris Tao; Sharon Szeto; Pamela Rosato; Jennifer Sela; Carl M Kadie; Nicole Frahm; Christian Brander; David W Haas; Sharon A Riddler; Richard Haubrich; Bruce D Walker; P Richard Harrigan; David Heckerman; Simon Mallal
HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins.
PloS one 2009;4(8):e6687.
2009: Santiago Avila-Rios; Christopher E Ormsby; Jonathan M Carlson; Humberto Valenzuela-Ponce; Juan Blanco-Heredia; Daniela Garrido-Rodriguez; Claudia Garcia-Morales; David Heckerman; Zabrina L Brumme; Simon Mallal; Mina John; Enrique Espinosa; Gustavo Reyes-Teran
Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study.
Retrovirology 2009;6():72.
2009: Elizabeth Phillips; Simon Mallal
Successful translation of pharmacogenetics into the clinic: the abacavir example.
Molecular diagnosis & therapy 2009;13(1):1-9.
2008: Emma Hammond; Elizabeth J McKinnon; Simon Mallal; David Nolan
Longitudinal evaluation of cardiovascular disease-associated biomarkers in relation to abacavir therapy.
AIDS (London, England) 2008;22(18):2540-3.
2008: Zabrina L Brumme; Chanson J Brumme; Jonathan Carlson; Hendrik Streeck; Mina John; Quentin Eichbaum; Brian L Block; Brett Baker; Carl Kadie; Martin Markowitz; Heiko Jessen; Anthony D Kelleher; Eric Rosenberg; John Kaldor; Yuko Yuki; Mary Carrington; Todd M Allen; Simon Mallal; Marcus Altfeld; David Heckerman; Bruce D Walker
Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection.
Journal of virology 2008;82(18):9216-27.
2008: Andri Rauch; David Nolan; Hansjakob Furrer; Elizabeth McKinnon; Mina John; Simon Mallal; Silvana Gaudieri; Huldrych F Günthard; Patrick Schmid; Manuel Battegay; Bernard Hirschel; Amalio Telenti; Ian James
HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(12):1921-5.
2008: Diana Chessman; Lyudmila Kostenko; Tessa Lethborg; Anthony W Purcell; Nicholas A Williamson; Zhenjun Chen; Lars Kjer-Nielsen; Nicole Mifsud; Brian D Tait; Rhonda Holdsworth; Coral-Ann Almeida; David Nolan; Whitney A Macdonald; Julia K Archbold; Anthony D Kellerher; Debbie Marriott; Simon Mallal; Mandvi Bharadwaj; Jamie Rossjohn; James McCluskey
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity.
Immunity 2008;28(6):822-32.
2008: Emma Hammond; Annalise Martin; David Nolan; Cecily Metcalf; Simon Mallal
Eruptive haemangioma associated with HIV therapy and mitochondrial pathology.
Pathology 2008;40(4):425-9.
2008: Michael Saag; Rukmini Balu; Elizabeth Phillips; Philip Brachman; Claudia Martorell; William Burman; Britt Stancil; Michael Mosteller; Cindy Brothers; Paul Wannamaker; Arlene Hughes; Denise Sutherland-Phillips; Simon Mallal; Mark Shaefer
High sensitivity of human leukocyte antigen-b*5701 as a marker for immunologically confirmed abacavir hypersensitivity in white and black patients.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(7):1111-8.
2008: Simon Mallal; Elizabeth Phillips; Giampiero Carosi; Jean-Michel Molina; Cassy Workman; Janez Tomazic; Eva Jägel-Guedes; Sorin Rugina; Oleg Kozyrev; Juan Flores Cid; Phillip Hay; David Nolan; Sara Hughes; Arlene Hughes; Susanna Ryan; Nicholas Fitch; Daren Thorborn; Alastair Benbow
HLA-B*5701 screening for hypersensitivity to abacavir.
The New England journal of medicine 2008;358(6):568-79.
2008: Elizabeth J Phillips; Simon Mallal
Pharmacogenetics and the potential for the individualization of antiretroviral therapy.
Current opinion in infectious diseases 2008;21(1):16-24.
2008: Andri Rauch; David Nolan; Christine Thurnheer; Christoph A Fux; Matthias Cavassini; Jean-Philippe Chave; Milos Opravil; Elizabeth Phillips; Simon Mallal; Hansjakob Furrer
Refining abacavir hypersensitivity diagnoses using a structured clinical assessment and genetic testing in the Swiss HIV Cohort Study.
Antiviral therapy 2008;13(8):1019-28.
2008: Coral-Ann Almeida; Annalise M Martin; David Nolan; Andrew Lucas; paul cameron; Ian James; Elizabeth Phillips; Simon Mallal
Cytokine profiling in abacavir hypersensitivity patients.
Antiviral therapy 2008;13(2):281-8.
2008: S Herrmann; Elizabeth J McKinnon; Mina John; N Hyland; O P Martinez; A Cain; K Turner; A Coombs; C Manolikos; Simon Mallal
Evidence-based, multifactorial approach to addressing non-adherence to antiretroviral therapy and improving standards of care.
Internal medicine journal 2008;38(1):8-15.
2007: Alexandre Harari; Cristina Cellerai; Felicitas Bellutti Enders; Josef Köstler; Laura Codarri; Gonzalo Tapia; Onur Boyman; Erika Castro; Silvana Gaudieri; Ian James; Mina John; Ralf Wagner; Simon Mallal; Giuseppe Pantaleo
Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(41):16233-8.
2007: Nicole Frahm; Karina Yusim; Todd J Suscovich; Sharon Adams; John Sidney; Peter T Hraber; Hannah S Hewitt; Caitlyn H Linde; Daniel G Kavanagh; Tonia Woodberry; Leah M Henry; Kellie Faircloth; Jennifer Listgarten; Carl Kadie; Nebojsa Jojic; Kaori Sango; Nancy V Brown; Eunice Pae; M Tauheed Zaman; Florian Bihl; Ashok Khatri; Mina John; Simon Mallal; Francesco M Marincola; Bruce D Walker; Alessandro Sette; David Heckerman; Bette T Korber; Christian Brander
Extensive HLA class I allele promiscuity among viral CTL epitopes.
European journal of immunology 2007;37(9):2419-33.
2007: Jacques Fellay; Kevin V Shianna; Dongliang Ge; Sara Colombo; bruno ledergerber; Mike Weale; Kunlin Zhang; Curtis Gumbs; Antonella Castagna; Andrea Cossarizza; Alessandro Cozzi-Lepri; Andrea De Luca; Philippa Easterbrook; Patrick Francioli; Simon Mallal; Javier Martinez-Picado; Jose M Miro; Niels Obel; Jason P Smith; Josiane Wyniger; Patrick Descombes; Stylianos E Antonarakis; Norman L Letvin; Andrew J McMichael; Barton F Haynes; Amalio Telenti; David B Goldstein
A whole-genome association study of major determinants for host control of HIV-1.
Science (New York, N.Y.) 2007;317(5840):944-7.
2007: Elizabeth Phillips; Simon Mallal
Drug hypersensitivity in HIV.
Current opinion in allergy and clinical immunology 2007;7(4):324-30.
2007: Emma Hammond; Cyril Mamotte; David Nolan; Simon Mallal
HLA-B*5701 typing: evaluation of an allele-specific polymerase chain reaction melting assay.
Tissue antigens 2007;70(1):58-61.
2007: Annalise M Martin; Coral-Ann Almeida; paul cameron; Anthony W Purcell; David Nolan; Ian James; James McCluskey; Elizabeth Phillips; Alan Landay; Simon Mallal
Immune responses to abacavir in antigen-presenting cells from hypersensitive patients.
AIDS (London, England) 2007;21(10):1233-44.
2007: Andrew Lucas; David Nolan; Simon Mallal
HLA-B*5701 screening for susceptibility to abacavir hypersensitivity.
The Journal of antimicrobial chemotherapy 2007;59(4):591-3.
2007: Tanmoy Bhattacharya; Marcus Daniels; David Heckerman; Brian Foley; Nicole Frahm; Carl Kadie; Jonathan Carlson; Karina Yusim; Ben McMahon; Brian Gaschen; Simon Mallal; James I Mullins; David C Nickle; Joshua Herbeck; Christine M Rousseau; Gerald Learn; Toshiyuki Miura; Christian Brander; Bruce Walker; Bette Korber
Founder effects in the assessment of HIV polymorphisms and HLA allele associations.
Science (New York, N.Y.) 2007;315(5818):1583-6.
2007: Elwyn Gabutero; Corey Moore; Simon Mallal; Graeme Stewart; Peter Williamson
Interaction between allelic variation in IL12B and CCR5 affects the development of AIDS: IL12B/CCR5 interaction and HIV/AIDS.
AIDS (London, England) 2007;21(1):65-9.
2007: Emma Hammond; Coral-Ann Almeida; Cyril Mamotte; David Nolan; Elizabeth Phillips; Tineke Asma Schollaardt; M John Gill; Jonathan B Angel; Doris Neurath; Jianping Li; Tony Giulivi; Cathy McIntyre; Galina Koultchitski; Betty Wong; Marciano Reis; Anita Rachlis; David E Cole; Choo Beng Chew; Stefan Neifer; Richard Lalonde; Michel Roger; Annie Jeanneau; Simon Mallal
External quality assessment of HLA-B*5701 reporting: an international multicentre survey.
Antiviral therapy 2007;12(7):1027-32.
2007: Jonathan Carlson; Carl Kadie; Simon Mallal; David Heckerman
Leveraging hierarchical population structure in discrete association studies.
PloS one 2007;2(7):e591.
2006: Silvana Gaudieri; Andri Rauch; Lawrence Park; Elizabeth M Freitas; Susan Herrmann; Gary Jeffrey; Wendy Cheng; Katja Pfafferott; Kiloshni Naidoo; Russell Chapman; Manuel Battegay; Rainer Weber; Amalio Telenti; Hansjakob Furrer; Ian James; Michaela Lucas; Simon Mallal
Evidence of viral adaptation to HLA class I-restricted immune pressure in chronic hepatitis C virus infection.
Journal of virology 2006;80(22):11094-104.
2006: Craig Pace; JEAN KELLER; David Nolan; Ian James; Silvana Gaudieri; Corey Moore; Simon Mallal
Population level analysis of human immunodeficiency virus type 1 hypermutation and its relationship with APOBEC3G and vif genetic variation.
Journal of virology 2006;80(18):9259-69.
2006: Catherine L Cherry; David Nolan; Ian R James; Elizabeth J McKinnon; Simon Mallal; Michelle E Gahan; Luxshimi Lal; justin charles mcarthur; Steven L Wesselingh
Tissue-specific associations between mitochondrial DNA levels and current treatment status in HIV-infected individuals.
Journal of acquired immune deficiency syndromes (1999) 2006;42(4):435-40.
2006: David Nolan; Silvana Gaudieri; Simon Mallal
Host genetics and viral infections: immunology taught by viruses, virology taught by the immune system.
Current opinion in immunology 2006;18(4):413-21.
2006: A Rauch; David Nolan; A Martin; Elizabeth J McKinnon; C Almeida; Simon Mallal
Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;43(1):99-102.
2006: Simon Mallal
Host genetics unplugged: removing the camouflage of viral adaptation.
Current opinion in HIV and AIDS 2006;1(3):218-9.
2006: Annalise M Martin; Romano Krueger; Coral-Ann Almeida; David Nolan; Elizabeth Phillips; Simon Mallal
A sensitive and rapid alternative to HLA typing as a genetic screening test for abacavir hypersensitivity syndrome.
Pharmacogenetics and genomics 2006;16(5):353-7.
2006: Florian Bihl; Nicole Frahm; Loriana Di Giammarino; John Sidney; Mina John; Karina Yusim; Tonia Woodberry; Kaori Sango; Hannah S Hewitt; Leah Henry; Caitlyn H Linde; John V Chisholm; Tauheed M Zaman; Eunice Pae; Simon Mallal; Bruce D Walker; Alessandro Sette; Bette T Korber; David Heckerman; Christian Brander
Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4094-101.
2006: David Nolan; Elizabeth Phillips; Simon Mallal
Efavirenz and CYP2B6 polymorphism: implications for drug toxicity and resistance.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2006;42(3):408-10.
2006: Nicole Frahm; Photini Kiepiela; Sharon Adams; Caitlyn H Linde; Hannah S Hewitt; Kaori Sango; Margaret E Feeney; Marylyn M Addo; Mathias Lichterfeld; Matthew P Lahaie; Eunice Pae; Alysse Wurcel; Timothy Roach; M Anne St John; Marcus Altfeld; Francesco M Marincola; Corey Moore; Simon Mallal; Mary Carrington; David Heckerman; Todd M Allen; James I Mullins; Bette T Korber; Philip J R Goulder; Bruce D Walker; Christian Brander
Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes.
Nature immunology 2006;7(2):173-8.
2006: Annalise Martin; David Nolan; Coral-Ann Almeida; Andri Rauch; Simon Mallal
Predicting and diagnosing abacavir and nevirapine drug hypersensitivity: from bedside to bench and back again.
Pharmacogenomics 2006;7(1):15-23.
2005: Francesc Vidal; Consuelo Viladés; Pere Domingo; Montserrat Broch; Enric Pedrol; David Dalmau; Hernando Knobel; Joaquim Peraire; Cristina Gutiérrez; Maria Antonia Sambeat; Angels Fontanet; Elisabet Deig; Mireia Cairó; Milagros Montero; Cristóbal Richart; Simon Mallal
Spanish HIV-1-infected long-term nonprogressors of more than 15 years have an increased frequency of the CX3CR1 249I variant allele.
Journal of acquired immune deficiency syndromes (1999) 2005;40(5):527-31.
2005: Silvana Gaudieri; D DeSantis; Elizabeth J McKinnon; C Moore; David Nolan; Campbell S Witt; Simon Mallal; Frank T Christiansen
Killer immunoglobulin-like receptors and HLA act both independently and synergistically to modify HIV disease progression.
Genes and immunity 2005;6(8):683-90.
2005: Todd M Allen; Marcus Altfeld; Shaun C Geer; Elizabeth T Kalife; Corey Moore; Kristin M O'Sullivan; Ivna Desouza; Margaret E Feeney; Robert L Eldridge; Erica L Maier; Daniel E Kaufmann; Matthew P Lahaie; Laura L Reyor; Giancarlo O Tanzi; Mary N Johnston; Christian Brander; Rika Draenert; Jürgen K Rockstroh; Heiko Jessen; Eric S Rosenberg; Simon Mallal; Bruce D Walker
Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.
Journal of virology 2005;79(21):13239-49.
2005: Todd M Allen; Xu G Yu; Elizabeth T Kalife; Laura L Reyor; Mathias Lichterfeld; Mina John; Michael Cheng; Rachel L Allgaier; Stanley K Mui; Nicole Frahm; Galit Alter; Nancy V Brown; Mary N Johnston; Eric S Rosenberg; Simon Mallal; Christian Brander; Bruce D Walker; Marcus Altfeld
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection.
Journal of virology 2005;79(20):12952-60.
2005: Margaret E Feeney; Yanhua Tang; Katja Pfafferott; Kathleen A Roosevelt; Rika Draenert; Alicja Trocha; Xu G Yu; Cori L Verrill; Todd Allen; Corey Moore; Simon Mallal; Sandra K Burchett; Kenneth McIntosh; Stephen I Pelton; M Anne St John; Rohan Hazra; Paul Klenerman; Marcus Altfeld; Bruce D Walker; Philip J R Goulder
HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(12):7524-30.
2005: Elizabeth J Phillips; Gavin A E Wong; Rupert Kaul; Kamnoosh Shahabi; David Nolan; Sandra R Knowles; Annalise M Martin; Simon Mallal; Neil H Shear
Clinical and immunogenetic correlates of abacavir hypersensitivity.
AIDS (London, England) 2005;19(9):979-81.
2005: Melissa J Gillett; paul cameron; Huong V Nguyen; David M Hurley; Simon Mallal
Iatrogenic Cushing's syndrome in an HIV-infected patient treated with ritonavir and inhaled fluticasone.
AIDS (London, England) 2005;19(7):740-1.
2005: Alasdair Leslie; Daniel Kavanagh; Isobella Honeyborne; Katja Pfafferott; Charles Edwards; Tilly Pillay; Louise Hilton; Christina Thobakgale; Danni Ramduth; Rika Draenert; Sylvie Le Gall; Graz Luzzi; Anne Edwards; Christian Brander; Andrew K Sewell; Sarah Moore; James Mullins; Corey Moore; Simon Mallal; Nina Bhardwaj; Karina Yusim; Rodney Phillips; Paul Klenerman; Bette Korber; Photini Kiepiela; Bruce Walker; Philip J R Goulder
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.
The Journal of experimental medicine 2005;201(6):891-902.
2005: David Nolan; Ian James; Simon Mallal
HIV/AIDS. HIV: experiencing the pressures of modern life.
Science (New York, N.Y.) 2005;307(5714):1422-4.
2005: David Nolan; Peter Reiss; Simon Mallal
Adverse effects of antiretroviral therapy for HIV infection: a review of selected topics.
Expert opinion on drug safety 2005;4(2):201-18.
2005: Mina John; Simon Mallal
CTL responses to HIV and SIV: wrestling with smoke.
Nature immunology 2005;6(3):232-4.
2005: Silvana Gaudieri; David Nolan; Elizabeth J McKinnon; Campbell S Witt; Simon Mallal; Frank T Christiansen
Associations between KIR epitope combinations expressed by HLA-B/-C haplotypes found in an HIV-1 infected study population may influence NK mediated immune responses.
Molecular immunology 2005;42(4):557-60.
2005: Annalise M Martin; David Nolan; Ian James; paul cameron; JEAN KELLER; Corey Moore; Elizabeth Phillips; Frank T Christiansen; Simon Mallal
Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T-cell counts.
AIDS (London, England) 2005;19(1):97-9.
2005: David Nolan; Simon Mallal
Antiretroviral-therapy-associated lipoatrophy: current status and future directions.
Sexual health 2005;2(3):153-63.
2005: Mina John; Corey B Moore; Ian R James; Simon Mallal
Interactive selective pressures of HLA-restricted immune responses and antiretroviral drugs on HIV-1.
Antiviral therapy 2005;10(4):551-5.
2004: Photini Kiepiela; Alasdair Leslie; Isobella Honeyborne; Danni Ramduth; Christina Thobakgale; Senica Chetty; Prinisha Rathnavalu; Corey Moore; Katja Pfafferott; Louise Hilton; Peter Zimbwa; Sarah Moore; Todd Allen; Christian Brander; Marylyn M Addo; Marcus Altfeld; Ian James; Simon Mallal; Mike Bunce; Linda D Barber; James Szinger; Cheryl Day; Paul Klenerman; James Mullins; Bette Korber; Hoosen M Coovadia; Bruce D Walker; Philip J R Goulder
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.
Nature 2004;432(7018):769-75.
2004: David Nolan; Simon Mallal
Complications associated with NRTI therapy: update on clinical features and possible pathogenic mechanisms.
Antiviral therapy 2004;9(6):849-63.
2004: Annalise M Martin; David Nolan; Silvana Gaudieri; Elizabeth Phillips; Simon Mallal
Pharmacogenetics of antiretroviral therapy: genetic variation of response and toxicity.
Pharmacogenomics 2004;5(6):643-55.
2004: Allison Martin; Don Smith; Andrew Carr; Jennifer Hoy; John Chuah; Simon Mallal; Matthew Law; Mark Clements; David A Cooper
Progression of lipodystrophy (LD) with continued thymidine analogue usage: long-term follow-up from a randomized clinical trial (the PIILR study).
HIV clinical trials 2004;5(4):192-200.
2004: Todd M Allen; Marcus Altfeld; Xu G Yu; Kristin M O'Sullivan; Mathias Lichterfeld; Sylvie Le Gall; Mina John; Bianca R Mothe; Paul K Lee; Elizabeth T Kalife; Daniel E Cohen; Kenneth A Freedberg; Daryld Strick; Mary N Johnston; Alessandro Sette; Eric S Rosenberg; Simon Mallal; Philip J R Goulder; Christian Brander; Bruce D Walker
Selection, transmission, and reversion of an antigen-processing cytotoxic T-lymphocyte escape mutation in human immunodeficiency virus type 1 infection.
Journal of virology 2004;78(13):7069-78.
2004: David Nolan; Silvana Gaudieri; Mina John; Simon Mallal
Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground.
AIDS (London, England) 2004;18(9):1231-40.
2004: David Nolan; Simon Mallal
The role of nucleoside reverse transcriptase inhibitors in the fat redistribution syndrome.
Journal of HIV therapy 2004;9(2):34-40.
2004: Emma Hammond; David Nolan; Ian James; Cecily Metcalf; Simon Mallal
Reduction of mitochondrial DNA content and respiratory chain activity occurs in adipocytes within 6-12 months of commencing nucleoside reverse transcriptase inhibitor therapy.
AIDS (London, England) 2004;18(5):815-7.
2004: Annalise M Martin; David Nolan; Silvana Gaudieri; Coral-Ann Almeida; Richard Nolan; Ian James; Filipa Carvalho; Elizabeth Phillips; Frank T Christiansen; Anthony W Purcell; James McCluskey; Simon Mallal
Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4180-5.
2003: David Nolan; Emma Hammond; Ian James; Elizabeth J McKinnon; Simon Mallal
Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level.
Antiviral therapy 2003;8(6):617-26.
2003: David Nolan; G F Watts; S E Herrmann; M A French; M John; Simon Mallal
Endothelial function in HIV-infected patients receiving protease inhibitor therapy: does immune competence affect cardiovascular risk?
QJM : monthly journal of the Association of Physicians 2003;96(11):825-32.
2003: Craig Pace; Annalise M Martin; Emma L Hammond; Cyril Mamotte; David Nolan; Simon Mallal
Mitochondrial proliferation, DNA depletion and adipocyte differentiation in subcutaneous adipose tissue of HIV-positive HAART recipients.
Antiviral therapy 2003;8(4):323-31.
2003: John Miller; Andrew Carr; Sean Emery; Matthew Law; Simon Mallal; D Baker; Don Smith; John Kaldor; David A Cooper
HIV lipodystrophy: prevalence, severity and correlates of risk in Australia.
HIV medicine 2003;4(3):293-301.
2003: David Nolan; Emma Hammond; Annalise Martin; Louise Taylor; Susan Herrmann; Elizabeth J McKinnon; Cecily Metcalf; Bruce Latham; Simon Mallal
Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy.
AIDS (London, England) 2003;17(9):1329-38.
2003: David Nolan; Silvana Gaudieri; Simon Mallal
Pharmacogenetics: a practical role in predicting antiretroviral drug toxicity?
Journal of HIV therapy 2003;8(2):36-41.
2003: Mina John; Elizabeth J McKinnon; Ian R James; David Nolan; Susan E Herrmann; Corey B Moore; Alex J White; Simon Mallal
Randomized, controlled, 48-week study of switching stavudine and/or protease inhibitors to combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients.
Journal of acquired immune deficiency syndromes (1999) 2003;33(1):29-33.
2003: Emma L Hammond; David C Sayer; David Nolan; Ulrich A Walker; Anthony de Ronde; Julio S G Montaner; Helene C F Cote; Michelle E Gahan; Catherine L Cherry; Steven L Wesselingh; Peter Reiss; Simon Mallal
Assessment of precision and concordance of quantitative mitochondrial DNA assays: a collaborative international quality assurance study.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2003;27(1):97-110.
2003: Annalise M Martin; Emma Hammond; David Nolan; Craig Pace; Marion Den Boer; Louise Taylor; Hannah Moore; Olga Patricia Martinez; Frank T Christiansen; Simon Mallal
Accumulation of mitochondrial DNA mutations in human immunodeficiency virus-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors.
American journal of human genetics 2003;72(3):549-60.
2003: Elizabeth J McKinnon; Ian R James; Mina John; Simon Mallal
Viral load detectability profiles for HIV infection.
Statistics in medicine 2003;22(3):385-96.
2003: David Nolan; Simon Mallal
Thymidine analogue-sparing highly active antiretroviral therapy (HAART).
Journal of HIV therapy 2003;8(1):2-6.
2003: David Nolan; Corey Moore; Alison Castley; David C Sayer; Cyril Mamotte; Mina John; Ian James; Simon Mallal
Tumour necrosis factor-alpha gene -238G/A promoter polymorphism associated with a more rapid onset of lipodystrophy.
AIDS (London, England) 2003;17(1):121-3.
2002: Corey B Moore; Mina John; Ian R James; Frank T Christiansen; Campbell S Witt; Simon Mallal
Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level.
Science (New York, N.Y.) 2002;296(5572):1439-43.
2002: Simon Mallal; David Nolan; Campbell Witt; G Masel; Annalise M Martin; Corey Moore; David C Sayer; Alison Castley; Cyril Mamotte; D Maxwell; Ian James; Frank T Christiansen
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.
Lancet 2002;359(9308):727-32.
2002: Mina John; Simon Mallal
Hyperlactatemia syndromes in people with HIV infection.
Current opinion in infectious diseases 2002;15(1):23-9.
2001: Andrew Carr; Jeff Hudson; John Chuah; Simon Mallal; Matthew Law; Jennifer Hoy; Nicholas Doong; Martyn French; Don Smith; David A Cooper
HIV protease inhibitor substitution in patients with lipodystrophy: a randomized, controlled, open-label, multicentre study.
AIDS (London, England) 2001;15(14):1811-22.
2001: David Nolan; Mina John; Simon Mallal
Antiretoviral therapy and the lipodystrophy syndrome, part 2: concepts in aetiopathogenesis.
Antiviral therapy 2001;6(3):145-60.
2001: David Nolan; R Upton; Elizabeth J McKinnon; Mina John; Ian James; B Adler; G Roff; S Vasikaran; Simon Mallal
Stable or increasing bone mineral density in HIV-infected patients treated with nelfinavir or indinavir.
AIDS (London, England) 2001;15(10):1275-80.
2001: David Nolan; Simon Mallal
Effects of sex and race on lipodystrophy pathogenesis.
Journal of HIV therapy 2001;6(2):32-6.
2001: Mina John; Corey B Moore; Ian R James; David Nolan; R P Upton; Elizabeth J McKinnon; Simon Mallal
Chronic hyperlactatemia in HIV-infected patients taking antiretroviral therapy.
AIDS (London, England) 2001;15(6):717-23.
2000: Simon Mallal; Mina John; Corey B Moore; Ian R James; Elizabeth J McKinnon
Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection.
AIDS (London, England) 2000;14(10):1309-16.
2000: Martyn A French; Nat P Lenzo; Mina John; Simon Mallal; Elizabeth J McKinnon; Ian R James; Patricia Price; James P Flexman; Mei-Ling Tay-Kearney
Immune restoration disease after the treatment of immunodeficient HIV-infected patients with highly active antiretroviral therapy.
HIV medicine 2000;1(2):107-15.
1999: Patricia Price; Campbell Witt; Richard J N Allcock; David C Sayer; Michael J Garlepp; CC Kok; Martyn French; Simon Mallal; Frank T Christiansen
The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases.
Immunological reviews 1999;167():257-74.
1998: Martyn French; N Lenzo; M John; Simon Mallal; Patricia Price
Highly active antiretroviral therapy.
Lancet 1998;351(9108):1056-7; author reply 1058-9.
1998: Simon Mallal
The Western Australian HIV Cohort Study, Perth, Australia.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;17 Suppl 1():S23-7.
1997: Gregory J Dore; Jennifer Hoy; Simon Mallal; Yueming Li; Anne Mijch; Martyn A French; David A Cooper; John M Kaldor
Trends in incidence of AIDS illnesses in Australia from 1983 to 1994: the Australian AIDS cohort.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997;16(1):39-43.
1996: Gregory J Dore; Yueming Li; Andrew E Grulich; Jennifer Hoy; Simon Mallal; Anne Mijch; Martyn A French; David A Cooper; John M Kaldor
Declining incidence and later occurrence of Kaposi's sarcoma among persons with AIDS in Australia: the Australian AIDS cohort.
AIDS (London, England) 1996;10(12):1401-6.
1995: J R Dyer; Martyn A French; Simon Mallal
Cerebral mass lesions due to cytomegalovirus in patients with AIDS: report of two cases.
The Journal of infection 1995;30(2):147-51.
1995: Guan K Tay; Campbell S Witt; Frank T Christiansen; D Charron; D Baker; R Herrmann; L K Smith; D Diepeveen; Simon Mallal; J McCluskey
Matching for MHC haplotypes results in improved survival following unrelated bone marrow transplantation.
Bone marrow transplantation 1995;15(3):381-5.
1994: Simon Mallal; I R James; Martyn A French
Detection of subclinical Mycobacterium avium intracellulare complex infection in immunodeficient HIV-infected patients treated with zidovudine.
AIDS (London, England) 1994;8(9):1263-9.
1994: Simon Mallal; O P Martinez; Martyn A French; I R James; Roger L Dawkins
Severity and outcome of Pneumocystis carinii pneumonia (PCP) in patients of known and unknown HIV status.
Journal of acquired immune deficiency syndromes 1994;7(2):148-53.
1992: D F Mallon; W Shearwood; Simon Mallal; Martyn A French; Roger L Dawkins
Exposure to blood borne infections in health care workers.
The Medical journal of Australia 1992;157(9):592-5.
1992: Martyn A French; Simon Mallal; Roger L Dawkins
Zidovudine-induced restoration of cell-mediated immunity to mycobacteria in immunodeficient HIV-infected patients.
AIDS (London, England) 1992;6(11):1293-7.
1992: S J Gillieatt; Simon Mallal; Martyn A French; Roger L Dawkins
Epidemiology of late presentation of HIV infection in Western Australia.
The Medical journal of Australia 1992;157(2):117-8.
1991: Frank T Christiansen; W J Zhang; M Griffiths; Simon Mallal; Roger L Dawkins
Major histocompatibility complex (MHC) complement deficiency, ancestral haplotypes and systemic lupus erythematosus (SLE): C4 deficiency explains some but not all of the influence of the MHC.
The Journal of rheumatology 1991;18(9):1350-8.
1990: paul cameron; Simon Mallal; Martyn A French; Roger L Dawkins
Major histocompatibility complex genes influence the outcome of HIV infection. Ancestral haplotypes with C4 null alleles explain diverse HLA associations.
Human immunology 1990;29(4):282-95.
1990: Simon Mallal; paul cameron; M A French; Roger L Dawkins
MHC genes and HIV infection.
Lancet 1990;335(8705):1591-2.