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Michael Baseler

Research Profile

Disorders

HIV Infections

Living Beings

HIV-1
HIV

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TOP 3
Xing Zhang; Terrence W Brann; Ming Zhou; Jun Yang; Raphael M Oguariri; Kristy B Lidie; Hiromi Imamichi; Da-Wei Huang; Richard A Lempicki; Michael Baseler; Timothy D Veenstra; Howard A Young; H Clifford Lane; Tomozumi Imamichi
Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.
Marta Catalfamo; Christopher Wilhelm; Lueng Tcheung; Michael A Proschan; Travis Friesen; Jung-Hyun Park; Joseph W Adelsberger; Michael Baseler; Frank Maldarelli; Richard Davey; Gregg Roby; Catherine A Rehm; Clifford Lane
CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, type I IFN, and IL-7.
Liubov Zaritskaya; Kimberly Shafer-Weaver; Melissa K Gregory; Susan L Strobl; Michael Baseler; Anatoli Malyguine
Application of a flow cytometric cytotoxicity assay for monitoring cancer vaccine trials.

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All Publications

2011: Xing Zhang; Terrence W Brann; Ming Zhou; Jun Yang; Raphael M Oguariri; Kristy B Lidie; Hiromi Imamichi; Da-Wei Huang; Richard A Lempicki; Michael Baseler; Timothy D Veenstra; Howard A Young; H Clifford Lane; Tomozumi Imamichi
Cutting edge: Ku70 is a novel cytosolic DNA sensor that induces type III rather than type I IFN.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4541-5.
2011: Marta Catalfamo; Christopher Wilhelm; Lueng Tcheung; Michael A Proschan; Travis Friesen; Jung-Hyun Park; Joseph W Adelsberger; Michael Baseler; Frank Maldarelli; Richard Davey; Gregg Roby; Catherine A Rehm; Clifford Lane
CD4 and CD8 T cell immune activation during chronic HIV infection: roles of homeostasis, HIV, type I IFN, and IL-7.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(4):2106-16.
2009: Liubov Zaritskaya; Kimberly Shafer-Weaver; Melissa K Gregory; Susan L Strobl; Michael Baseler; Anatoli Malyguine
Application of a flow cytometric cytotoxicity assay for monitoring cancer vaccine trials.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(2):186-94.
2008: Jeanette Higgins; Julia A Metcalf; Randy A Stevens; Michael Baseler; Michael Proschan; H Clifford Lane; Irini Sereti
Effects of delays in peripheral blood processing, including cryopreservation, on detection of CD31 expression on naive CD4 T cells.
Clinical and vaccine immunology : CVI 2008;15(7):1141-3.
2008: Tomozumi Imamichi; Jun Yang; Da-Wei Huang; Terrence W Brann; Brandie A Fullmer; Joseph W Adelsberger; Richard A Lempicki; Michael Baseler; H Clifford Lane
IL-27, a novel anti-HIV cytokine, activates multiple interferon-inducible genes in macrophages.
AIDS (London, England) 2008;22(1):39-45.
2007: Jeanette Higgins; Valerie Hill; Karen Lau; Virginia Simpson; Jean Roayaei; Rick Klabansky; Randy A Stevens; Julia A Metcalf; Michael Baseler
Evaluation of a single-platform technology for lymphocyte immunophenotyping.
Clinical and vaccine immunology : CVI 2007;14(10):1342-8.
2007: Véronique Pascal; Eriko Yamada; Maureen P Martin; Galit Alter; Marcus Altfeld; Julia A Metcalf; Michael Baseler; Joseph W Adelsberger; Mary Carrington; Stephen K Anderson; Daniel W McVicar
Detection of KIR3DS1 on the cell surface of peripheral blood NK cells facilitates identification of a novel null allele and assessment of KIR3DS1 expression during HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1625-33.
2007: Da Wei Huang; Brad T Sherman; Qina Tan; Joseph Kir; David Liu; David Bryant; Yongjian Guo; Robert Stephens; Michael Baseler; H Clifford Lane; Richard A Lempicki
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists.
Nucleic acids research 2007;35(Web Server issue):W169-75.
2007: Brad T Sherman; Da Wei Huang; Qina Tan; Yongjian Guo; Stephan Bour; David Liu; Robert Stephens; Michael Baseler; H Clifford Lane; Richard A Lempicki
DAVID Knowledgebase: a gene-centered database integrating heterogeneous gene annotation resources to facilitate high-throughput gene functional analysis.
BMC bioinformatics 2007;8():426.
2007: Da Wei Huang; Brad T Sherman; Qina Tan; Jack R Collins; W Gregory Alvord; Jean Roayaei; Robert Stephens; Michael Baseler; H Clifford Lane; Richard A Lempicki
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists.
Genome biology 2007;8(9):R183.
2007: Anatoli Malyguine; Susan Strobl; Liubov Zaritskaya; Michael Baseler; Kimberly Shafer-Weaver
New approaches for monitoring CTL activity in clinical trials.
Advances in experimental medicine and biology 2007;601():273-84.
2006: Kimberly Shafer-Weaver; STEVEN ROSENBERG; Susan Strobl; W Gregory Alvord; Michael Baseler; Anatoli Malyguine
Application of the granzyme B ELISPOT assay for monitoring cancer vaccine trials.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2006;29(3):328-35.
2005: Richard A Morgan; Robert E Walker; Charles S Carter; Ven Natarajan; Jorge A Tavel; Chris Bechtel; Betsey Herpin; Linda Muul; Zhili Zheng; Shyla Jagannatha; Bruce A Bunnell; Vicki Fellowes; Julia A Metcalf; Randy Stevens; Michael Baseler; Susan F Leitman; Elizabeth J Read; R. Michael Blaese; H Clifford Lane
Preferential survival of CD4+ T lymphocytes engineered with anti-human immunodeficiency virus (HIV) genes in HIV-infected individuals.
Human gene therapy 2005;16(9):1065-74.
2005: Joseph A Kovacs; Richard A Lempicki; Igor A Sidorov; Joseph W Adelsberger; Irini Sereti; William Sachau; Grace Kelly; Julia A Metcalf; Richard Davey; Judith Falloon; Michael A Polis; Jorge A Tavel; Randy Stevens; Laurie Lambert; Douglas A Hosack; Marjorie Bosche; Haleem J Issaq; Stephen D Fox; Susan F Leitman; Michael Baseler; Henry Masur; Michele Di Mascio; Dimiter S Dimitrov; H Clifford Lane
Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in HIV-infected patients.
The Journal of clinical investigation 2005;115(8):2139-48.
2005: Mark W Burkett; Kimberly Shafer-Weaver; Susan Strobl; Michael Baseler; Anatoli Malyguine
A novel flow cytometric assay for evaluating cell-mediated cytotoxicity.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2005;28(4):396-402.
2005: Jeanette Higgins; Julia A Metcalf; Randy A Stevens; Michael Baseler; Martha C Nason; H Clifford Lane; Irini Sereti
Effects of lymphocyte isolation and timing of processing on detection of CD127 expression on T cells in human immunodeficiency virus-infected patients.
Clinical and diagnostic laboratory immunology 2005;12(1):228-30.
2005: Ligia A Pinto; Matthew Trivett; Dora Wallace; Jeanette Higgins; Michael Baseler; Masaki Terabe; Igor M Belyakov; Jay A Berzofsky; Allan Hildesheim
Fixation and cryopreservation of whole blood and isolated mononuclear cells: Influence of different procedures on lymphocyte subset analysis by flow cytometry.
Cytometry. Part B, Clinical cytometry 2005;63(1):47-55.
2004: Mark Dybul; Elizabeth Nies-Kraske; Robin L Dewar; Frank Maldarelli; Claire W Hallahan; Marybeth Daucher; Stephen C Piscitelli; Linda Ehler; Ann Weigand; Sarah Palmer; Julia A Metcalf; Richard Davey; Diane Rock Kress; April Powers; Ingrid Beck; Lisa Frenkel; Michael Baseler; John M Coffin; Anthony Fauci
A proof-of-concept study of short-cycle intermittent antiretroviral therapy with a once-daily regimen of didanosine, lamivudine, and efavirenz for the treatment of chronic HIV infection.
The Journal of infectious diseases 2004;189(11):1974-82.
2003: Stephen D Fox; Richard A Lempicki; Douglas A Hosack; Michael Baseler; Joseph A Kovacs; H Clifford Lane; Timothy D Veenstra; Haleem J Issaq
A comparison of microLC/electrospray ionization-MS and GC/MS for the measurement of stable isotope enrichment from a [2H2]-glucose metabolic probe in T-cell genomic DNA.
Analytical chemistry 2003;75(23):6517-22.
2003: Jorge A Tavel; Irini Sereti; Robert E Walker; Barbara Hahn; Joseph A Kovacs; Shyla Jagannatha; Richard Davey; Judith Falloon; Michael A Polis; Henry Masur; Julia A Metcalf; Randy Stevens; Adam Rupert; Michael Baseler; H Clifford Lane
A randomized, double-blinded, placebo-controlled trial of intermittent administration of interleukin-2 and prednisone in subjects infected with human immunodeficiency virus.
The Journal of infectious diseases 2003;188(4):531-6.
2003: Ligia A Pinto; Jessica Edwards; Philip E Castle; Clayton D Harro; Douglas Lowy; John T Schiller; Dora Wallace; William Kopp; Joseph W Adelsberger; Michael Baseler; Jay A Berzofsky; Allan Hildesheim
Cellular immune responses to human papillomavirus (HPV)-16 L1 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles.
The Journal of infectious diseases 2003;188(2):327-38.
2003: Tomozumi Imamichi; Michael A Murphy; Joseph W Adelsberger; Jun Yang; Catherine M Watkins; Steve C Berg; Michael Baseler; Richard A Lempicki; Jianhui Guo; Judith G Levin; H Clifford Lane
Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression.
Journal of virology 2003;77(2):1011-20.
2002: Irini Sereti; Hector Martinez-Wilson; Julia A Metcalf; Michael Baseler; Claire W Hallahan; Barbara Hahn; Richard L Hengel; Richard Davey; Joseph A Kovacs; H Clifford Lane
Long-term effects of intermittent interleukin 2 therapy in patients with HIV infection: characterization of a novel subset of CD4(+)/CD25(+) T cells.
Blood 2002;100(6):2159-67.
2002: Ven Natarajan; Richard A Lempicki; Irini Sereti; Yunden Badralmaa; Joseph W Adelsberger; Julia A Metcalf; DaRue A Prieto; Randy Stevens; Michael Baseler; Joseph A Kovacs; H Clifford Lane
Increased peripheral expansion of naive CD4+ T cells in vivo after IL-2 treatment of patients with HIV infection.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10712-7.
2002: Anatoli Malyguine; Eric Derby; Alan Brooks; Vasavi Reddy; Michael Baseler; Thomas Sayers
Study of diverse mechanisms of cell-mediated cytotoxicity in gene-targeted mice using flow cytometric cytotoxicity assay.
Immunology letters 2002;83(1):55-9.
2001: Mark Dybul; Tae-Wook Chun; Christian Yoder; Bertha Hidalgo; Michael Belson; Kurt Hertogs; B Larder; Robin L Dewar; CH Fox; Claire W Hallahan; J Shawn Justement; Stephen A Migueles; Julia A Metcalf; Richard Davey; Marybeth Daucher; Punita Pandya; Michael Baseler; Douglas J Ward; Anthony Fauci
Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: effects on virologic, immunologic, and toxicity parameters.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15161-6.
2001: Joseph A Kovacs; Richard A Lempicki; Igor A Sidorov; Joseph W Adelsberger; Betsey Herpin; Julia A Metcalf; Irini Sereti; Michael A Polis; Richard Davey; Jorge A Tavel; Judith Falloon; Randy Stevens; Laurie Lambert; Robin L Dewar; DJ Schwartzentruber; M R Anver; Michael Baseler; Henry Masur; Dimiter S Dimitrov; H Clifford Lane
Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV.
The Journal of experimental medicine 2001;194(12):1731-41.
2001: Daniel C Douek; Michael R Betts; Brenna J Hill; S J Little; Richard A Lempicki; Julia A Metcalf; Joseph P Casazza; Christian Yoder; Joseph W Adelsberger; Randy A Stevens; Michael Baseler; Philip H Keiser; Douglas D Richman; Richard Davey; Richard A Koup
Evidence for increased T cell turnover and decreased thymic output in HIV infection.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6663-8.
2001: Irini Sereti; Betsey Herpin; Julia A Metcalf; R Stevens; Michael Baseler; Claire W Hallahan; Joseph A Kovacs; Richard Davey; H Clifford Lane
CD4 T cell expansions are associated with increased apoptosis rates of T lymphocytes during IL-2 cycles in HIV infected patients.
AIDS (London, England) 2001;15(14):1765-75.
2001: Eric Derby; Vasavi Reddy; Michael Baseler; Anatoli Malyguine
Flow cytometric assay for the simultaneous analysis of cell-mediated cytotoxicity and effector cell phenotype.
BioTechniques 2001;31(3):660, 664-5.
2001: Susan Moir; Angela Malaspina; Kisani M Ogwaro; Eileen T Donoghue; Claire W Hallahan; Linda Ehler; Shiquan Liu; Joseph W Adelsberger; Réjean Lapointe; Patrick Hwu; Michael Baseler; Jan M Orenstein; Tae-Wook Chun; Jo Ann M Mican; Anthony Fauci
HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10362-7.
2001: Eric Derby; Vasavi Reddy; W Kopp; E Nelson; Michael Baseler; T Sayers; Anatoli Malyguine
Three-color flow cytometric assay for the study of the mechanisms of cell-mediated cytotoxicity.
Immunology letters 2001;78(1):35-9.
2001: Joseph A Kovacs; S Vogel; Julia A Metcalf; Michael Baseler; Randy Stevens; Joseph W Adelsberger; Richard A Lempicki; Richard L Hengel; Irini Sereti; Laurie Lambert; Robin L Dewar; Richard Davey; Robert E Walker; Judith Falloon; Michael A Polis; Henry Masur; H Clifford Lane
Interleukin-2 induced immune effects in human immunodeficiency virus-infected patients receiving intermittent interleukin-2 immunotherapy.
European journal of immunology 2001;31(5):1351-60.
2000: Richard A Lempicki; Joseph A Kovacs; Michael Baseler; Joseph W Adelsberger; Robin L Dewar; Ven Natarajan; Marjorie Bosche; Julia A Metcalf; Randy A Stevens; L A Lambert; W G Alvord; Michael A Polis; Richard Davey; Dimiter S Dimitrov; H Clifford Lane
Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(25):13778-83.
2000: JC Gea-Banacloche; L Martino; JoAnn M Mican; Claire W Hallahan; Michael Baseler; Randy Stevens; Laurie Lambert; Michael A Polis; H Clifford Lane; Mark Connors
Longitudinal changes in CD4+ T cell antigen receptor diversity and naive/memory cell phenotype during 9 to 26 months of antiretroviral therapy of HIV-infected patients.
AIDS research and human retroviruses 2000;16(17):1877-86.
2000: Joseph A Kovacs; Hiromi Imamichi; S Vogel; Julia A Metcalf; Robin L Dewar; Michael Baseler; Randy Stevens; Joseph W Adelsberger; Laurie Lambert; Richard Davey; Robert E Walker; Judith Falloon; Michael A Polis; Henry Masur; H Clifford Lane
Effects of intermittent interleukin-2 therapy on plasma and tissue human immunodeficiency virus levels and quasi-species expression.
The Journal of infectious diseases 2000;182(4):1063-9.
2000: Susan Moir; Angela Malaspina; Y Li; Tae-Wook Chun; T Lowe; Joseph W Adelsberger; Michael Baseler; Linda Ehler; Shiquan Liu; Richard Davey; Jo Ann M Mican; Anthony Fauci
B cells of HIV-1-infected patients bind virions through CD21-complement interactions and transmit infectious virus to activated T cells.
The Journal of experimental medicine 2000;192(5):637-46.
2000: Robert E Walker; Chris Bechtel; Ven Natarajan; Michael Baseler; Kristen M Hege; Julia A Metcalf; Randy Stevens; A Hazen; R. Michael Blaese; C C Chen; Susan F Leitman; J Palensky; J Wittes; Richard Davey; Judith Falloon; Michael A Polis; Joseph A Kovacs; David F Broad; B L Levine; MR Roberts; Henry Masur; H Clifford Lane
Long-term in vivo survival of receptor-modified syngeneic T cells in patients with human immunodeficiency virus infection.
Blood 2000;96(2):467-74.
1999: Richard Davey; Niranjan Bhat; Christian Yoder; Tae-Wook Chun; Julia A Metcalf; Robin L Dewar; Ven Natarajan; Richard A Lempicki; Joseph W Adelsberger; Kirk D Miller; Joseph A Kovacs; Michael A Polis; Robert E Walker; Judith Falloon; Henry Masur; Dennis Gee; Michael Baseler; Dimiter S Dimitrov; Anthony Fauci; H Clifford Lane
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15109-14.
1999: Susan Moir; Réjean Lapointe; Angela Malaspina; M Ostrowski; C E Cole; Tae-Wook Chun; Joseph W Adelsberger; Michael Baseler; Patrick Hwu; Anthony Fauci
CD40-Mediated induction of CD4 and CXCR4 on B lymphocytes correlates with restricted susceptibility to human immunodeficiency virus type 1 infection: potential role of B lymphocytes as a viral reservoir.
Journal of virology 1999;73(10):7972-80.
1999: Richard Davey; Doreen G Chaitt; J M Albert; Stephen C Piscitelli; Joseph A Kovacs; Robert E Walker; Judith Falloon; Michael A Polis; Julia A Metcalf; Henry Masur; Robin L Dewar; Michael Baseler; Gwendolyn Fyfe; M A Giedlin; H Clifford Lane
A randomized trial of high- versus low-dose subcutaneous interleukin-2 outpatient therapy for early human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1999;179(4):849-58.
1998: Stephen C Piscitelli; Stefanie N Vogel; William D Figg; Sangeeta Raje; A Forrest; Julia A Metcalf; Michael Baseler; Judith Falloon
Alteration in indinavir clearance during interleukin-2 infusions in patients infected with the human immunodeficiency virus.
Pharmacotherapy 1998;18(6):1212-6.
1998: Stephen C Piscitelli; A Forrest; S Vogel; Doreen G Chaitt; Julia Metcalf; R Stevens; Michael Baseler; Richard Davey; Joseph A Kovacs
Pharmacokinetic modeling of recombinant interleukin-2 in patients with human immunodeficiency virus infection.
Clinical pharmacology and therapeutics 1998;64(5):492-8.
1998: Robert E Walker; C S Carter; Linda Muul; Ven Natarajan; Betsey Herpin; Susan F Leitman; HARVEY KLEIN; Craig A Mullen; Julia A Metcalf; Michael Baseler; Judith Falloon; Richard Davey; Joseph A Kovacs; Michael A Polis; Henry Masur; R. Michael Blaese; H Clifford Lane
Peripheral expansion of pre-existing mature T cells is an important means of CD4+ T-cell regeneration HIV-infected adults.
Nature medicine 1998;4(7):852-6.
1998: JC Gea-Banacloche; E E Weiskopf; Claire W Hallahan; J C López Bernaldo de Quirós; M Flanigan; JoAnn M Mican; Judith Falloon; Michael Baseler; Randy Stevens; H Clifford Lane; Mark Connors
Progression of human immunodeficiency virus disease is associated with increasing disruptions within the CD4+ T cell receptor repertoire.
The Journal of infectious diseases 1998;177(3):579-85.
1997: Tae-Wook Chun; Lieven Stuyver; SB Mizell; Linda Ehler; Jo Ann M Mican; Michael Baseler; A L Lloyd; M A Nowak; Anthony Fauci
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(24):13193-7.
1997: OJ Cohen; M Vaccarezza; G K Lam; BF Baird; K Wildt; Philip M Murphy; Peter Zimmerman; Thomas B Nutman; CH Fox; S Hoover; Joseph W Adelsberger; Michael Baseler; James Arthos; Richard Davey; Robin L Dewar; Julia Metcalf; DJ Schwartzentruber; Jan M Orenstein; Susan Buchbinder; Alfred J Saah; Roger Detels; John Phair; Charles Rinaldo; Joseph B Margolick; Giuseppe Pantaleo; Anthony Fauci
Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors.
The Journal of clinical investigation 1997;100(6):1581-9.
1997: S Lee; Harris Goldstein; Michael Baseler; Joseph W Adelsberger; Hana Golding
Human immunodeficiency virus type 1 infection of mature CD3hiCD8+ thymocytes.
Journal of virology 1997;71(9):6671-6.
1997: Mark Connors; Joseph A Kovacs; S Krevat; JC Gea-Banacloche; michael sneller; M Flanigan; Julia A Metcalf; Robert E Walker; Judith Falloon; Michael Baseler; IM Feuerstein; Henry Masur; H Clifford Lane
HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies.
Nature medicine 1997;3(5):533-40.
1996: Joseph A Kovacs; S Vogel; J M Albert; Judith Falloon; Richard Davey; Robert E Walker; Michael A Polis; K Spooner; Julia A Metcalf; Michael Baseler; Gwendolyn Fyfe; H Clifford Lane
Controlled trial of interleukin-2 infusions in patients infected with the human immunodeficiency virus.
The New England journal of medicine 1996;335(18):1350-6.
1996: Stephen C Piscitelli; M J Wells; Julia A Metcalf; Michael Baseler; R Stevens; Richard Davey
Pharmacokinetics and pharmacodynamics of subcutaneous interleukin-2 in HIV-infected patients.
Pharmacotherapy 1996;16(5):754-9.
1996: Robert E Walker; K M Spooner; G Kelly; R V McCloskey; J N Woody; Judith Falloon; Michael Baseler; Stephen C Piscitelli; Richard Davey; Michael A Polis; Joseph A Kovacs; Henry Masur; H Clifford Lane
Inhibition of immunoreactive tumor necrosis factor-alpha by a chimeric antibody in patients infected with human immunodeficiency virus type 1.
The Journal of infectious diseases 1996;174(1):63-8.
1996: Drew Weissman; J Daucher; T Barker; Joseph W Adelsberger; Michael Baseler; Anthony Fauci
Cytokine regulation of HIV replication induced by dendritic cell-CD4-positive T cell interactions.
AIDS research and human retroviruses 1996;12(9):759-67.
1996: Joseph A Kovacs; C Bechtel; Richard Davey; Judith Falloon; Michael A Polis; Robert E Walker; Julia A Metcalf; Victoria Davey; Stephen C Piscitelli; Michael Baseler; Robin L Dewar; N P Salzman; Henry Masur; H Clifford Lane
Combination therapy with didanosine and interferon-alpha in human immunodeficiency virus-infected patients: results of a phase I/II trial.
The Journal of infectious diseases 1996;173(4):840-8.
1995: M J Boyle; Mark Connors; M E Flanigan; S P Geiger; Harry Ford; Michael Baseler; Joseph W Adelsberger; Richard Davey; H Clifford Lane
The human HIV/peripheral blood lymphocyte (PBL)-SCID mouse. A modified human PBL-SCID model for the study of HIV pathogenesis and therapy.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6612-23.
1995: A Foli; MW Saville; Michael Baseler; Robert Yarchoan
Effects of the Th1 and Th2 stimulatory cytokines interleukin-12 and interleukin-4 on human immunodeficiency virus replication.
Blood 1995;85(8):2114-23.
1995: Joseph A Kovacs; Michael Baseler; R J Dewar; S Vogel; Richard Davey; Judith Falloon; Michael A Polis; Robert E Walker; R Stevens; N P Salzman
Increases in CD4 T lymphocytes with intermittent courses of interleukin-2 in patients with human immunodeficiency virus infection. A preliminary study.
The New England journal of medicine 1995;332(9):567-75.
1995: Drew Weissman; Y Li; J Ananworanich; L J Zhou; Joseph W Adelsberger; Thomas F Tedder; Michael Baseler; Anthony Fauci
Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):826-30.
1994: michael sneller; E M Eisenstein; Michael Baseler; H Clifford Lane; E T Donoghue; Judith Falloon
A unique syndrome of immunodeficiency and autoimmunity associated with absent T cell CD2 expression.
Journal of clinical immunology 1994;14(6):359-67.
1994: SM Schnittman; S Vogel; Michael Baseler; H Clifford Lane; Richard Davey
A phase I study of interferon-alpha 2b in combination with interleukin-2 in patients with human immunodeficiency virus infection.
The Journal of infectious diseases 1994;169(5):981-9.
1993: S K Stanley; Joseph M McCune; H Kaneshima; J S Justement; M Sullivan; E Boone; Michael Baseler; Joseph W Adelsberger; ML Bonyhadi; Jan M Orenstein
Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse.
The Journal of experimental medicine 1993;178(4):1151-63.
1993: Scott Koenig; Robert M Woods; Yambasu Albert Brewah; A J Newell; G M Jones; E Boone; Joseph W Adelsberger; Michael Baseler; S M Robinson; Steven Jacobson
Characterization of MHC class I restricted cytotoxic T cell responses to tax in HTLV-1 infected patients with neurologic disease.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(7):3874-83.
1993: Joseph A Kovacs; M B Vasudevachari; M Easter; Richard Davey; Judith Falloon; Michael A Polis; Julia A Metcalf; N Salzman; Michael Baseler; G E Smith
Induction of humoral and cell-mediated anti-human immunodeficiency virus (HIV) responses in HIV sero-negative volunteers by immunization with recombinant gp160.
The Journal of clinical investigation 1993;92(2):919-28.
1993: J J Zurlo; D O'Neill; Michael A Polis; J Manischewitz; Robert Yarchoan; Michael Baseler; H Clifford Lane; Henry Masur
Lack of clinical utility of cytomegalovirus blood and urine cultures in patients with HIV infection.
Annals of internal medicine 1993;118(1):12-7.
1992: Robin L Dewar; M D Sarmiento; E S Lawton; H M Clark; P E Kennedy; A Shah; Michael Baseler; Julia A Metcalf; H Clifford Lane; N P Salzman
Isolation of HIV-1 from plasma of infected individuals: an analysis of experimental conditions affecting successful virus propagation.
Journal of acquired immune deficiency syndromes 1992;5(8):822-8.
1991: Andrea De Maria; Giuseppe Pantaleo; SM Schnittman; J J Greenhouse; Michael Baseler; Jan M Orenstein; Anthony Fauci
Infection of CD8+ T lymphocytes with HIV. Requirement for interaction with infected CD4+ cells and induction of infectious virus from chronically infected CD8+ cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2220-6.
1991: Paolo Lusso; Andrea De Maria; M Malnati; Franco Lori; S E DeRocco; Michael Baseler; Robert C Gallo
Induction of CD4 and susceptibility to HIV-1 infection in human CD8+ T lymphocytes by human herpesvirus 6.
Nature 1991;349(6309):533-5.
1990: SM Schnittman; S M Denning; J J Greenhouse; J S Justement; Michael Baseler; J Kurtzberg; Barton F Haynes; Anthony Fauci
Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta + and TCR gamma delta + to human immunodeficiency virus infection: a mechanism for CD4+ (T4) lymphocyte depletion.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7727-31.
1990: SM Schnittman; J J Greenhouse; M C Psallidopoulos; Michael Baseler; N P Salzman; Anthony Fauci; H Clifford Lane
Increasing viral burden in CD4+ T cells from patients with human immunodeficiency virus (HIV) infection reflects rapidly progressive immunosuppression and clinical disease.
Annals of internal medicine 1990;113(6):438-43.
1990: SM Schnittman; H Clifford Lane; J Greenhouse; J S Justement; Michael Baseler; Anthony Fauci
Preferential infection of CD4+ memory T cells by human immunodeficiency virus type 1: evidence for a role in the selective T-cell functional defects observed in infected individuals.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(16):6058-62.
1990: Giuseppe Pantaleo; Andrea De Maria; Scott Koenig; Luca Butini; Bernard Moss; Michael Baseler; H Clifford Lane; Anthony Fauci
CD8+ T lymphocytes of patients with AIDS maintain normal broad cytolytic function despite the loss of human immunodeficiency virus-specific cytotoxicity.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4818-22.
1990: Carlo Federico Perno; Michael Baseler; S Broder; Robert Yarchoan
Infection of monocytes by human immunodeficiency virus type 1 blocked by inhibitors of CD4-gp120 binding, even in the presence of enhancing antibodies.
The Journal of experimental medicine 1990;171(4):1043-56.
1990: Giuseppe Pantaleo; Scott Koenig; Michael Baseler; H Clifford Lane; Anthony Fauci
Defective clonogenic potential of CD8+ T lymphocytes in patients with AIDS. Expansion in vivo of a nonclonogenic CD3+CD8+DR+CD25- T cell population.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1696-704.
1990: SM Schnittman; S M Denning; J J Greenhouse; J S Justement; Michael Baseler; Barton F Haynes; Anthony Fauci
Evidence for susceptibility of intrathymic T cell precursors to human immunodeficiency virus infection: a mechanism for T4 (CD4) lymphocyte depletion.
Transactions of the Association of American Physicians 1990;103():96-101.
1989: M C Psallidopoulos; SM Schnittman; L M Thompson; Michael Baseler; Anthony Fauci; H Clifford Lane; N P Salzman
Integrated proviral human immunodeficiency virus type 1 is present in CD4+ peripheral blood lymphocytes in healthy seropositive individuals.
Journal of virology 1989;63(11):4626-31.
1989: SM Schnittman; M C Psallidopoulos; H Clifford Lane; L Thompson; Michael Baseler; F Massari; C H Fox; N P Salzman; Anthony Fauci
The reservoir for HIV-1 in human peripheral blood is a T cell that maintains expression of CD4.
Science (New York, N.Y.) 1989;245(4915):305-8.
1989: H Clifford Lane; Judith Falloon; Robert E Walker; L Deyton; Joseph A Kovacs; Henry Masur; S Banks; L E Kirk; Michael Baseler; N P Salzman
Zidovudine in patients with human immunodeficiency virus (HIV) infection and Kaposi sarcoma. A phase II randomized, placebo-controlled trial.
Annals of internal medicine 1989;111(1):41-50.
1988: H Clifford Lane; Joseph A Kovacs; J Feinberg; B Herpin; Victoria Davey; Robert E Walker; L Deyton; Julia A Metcalf; Michael Baseler; N Salzman
Anti-retroviral effects of interferon-alpha in AIDS-associated Kaposi's sarcoma.
Lancet 1988;2(8622):1218-22.