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Mahitosh Mandal

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TOP 3
Kacoli Sen; Mahitosh Mandal
Second generation liposomal cancer therapeutics: Transition from laboratory to clinic.
B Dinesh Kumar; Saravana Kumar Jaganathan; K Krishnakumar; Mahitosh Mandal
Effect of Mangiferin and Mahanimbine on Glucose Utilization in 3T3-L1 cells.
Shashi Rajput; Prasanna K. Santhekadur; Devanand Sarkar; Siddik Sarkar; Belal Azab; Subhasis Das; Swadesh K Das; Luni Emdad; Paul B Fisher; B N Prashanth Kumar; Mahitosh Mandal
Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer.

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All Publications

2013: Kacoli Sen; Mahitosh Mandal
Second generation liposomal cancer therapeutics: Transition from laboratory to clinic.
International journal of pharmaceutics 2013;448(1):28-43.
2013: B Dinesh Kumar; Saravana Kumar Jaganathan; K Krishnakumar; Mahitosh Mandal
Effect of Mangiferin and Mahanimbine on Glucose Utilization in 3T3-L1 cells.
Pharmacognosy magazine 2013;9(33):72-5.
2013: Shashi Rajput; Prasanna K. Santhekadur; Devanand Sarkar; Siddik Sarkar; Belal Azab; Subhasis Das; Swadesh K Das; Luni Emdad; Paul B Fisher; B N Prashanth Kumar; Mahitosh Mandal
Targeted Apoptotic Effects of Thymoquinone and Tamoxifen on XIAP Mediated Akt Regulation in Breast Cancer.
PloS one 2013;8(4):e61342.
2012: Ipsita Pal; Mahitosh Mandal
PI3K and Akt as molecular targets for cancer therapy: current clinical outcomes.
Acta pharmacologica Sinica 2012;33(12):1441-58.
2012: P Venkatesan; Devanand Sarkar; Abhay K Singh; Sujit K Bhutia; Koel Chaudhury; Swadesh K Das; Rupesh Dash; Paul B Fisher; Mahitosh Mandal
AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells.
Life sciences 2012;91(15-16):789-99.
2012: Shashi Rajput; Mahitosh Mandal
Antitumor promoting potential of selected phytochemicals derived from spices: a review.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2012;21(2):205-15.
2012: Subhasis Das; Kaushik Kumar Dey; Sukumar Maiti; Sujata MaitiChoudhury; Rashmi Bharti; Mahitosh Mandal
PKI 166 induced redox signalling and apoptosis through activation of p53, MAP kinase and caspase pathway in epidermoid carcinoma.
Journal of experimental therapeutics & oncology 2012;10(2):139-53.
2011: Sankar Ramachandran; Mahitosh Mandal
Induction of apoptosis of azurin synthesized from P. aeruginosa MTCC 2453 against Dalton's lymphoma ascites model.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2011;65(7):461-6.
2011: Saravana Kumar Jaganathan; Abhijit Mazumdar; Dilip Mondhe; Mahitosh Mandal
Apoptotic effect of eugenol in human colon cancer cell lines.
Cell biology international 2011;35(6):607-15.
2011: P Venkatesan; Nagaprasad Puvvada; Rupesh Dash; B N Prashanth Kumar; Devanand Sarkar; Belal Azab; Amita Pathak; Subhas C. Kundu; Paul B Fisher; Mahitosh Mandal
The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer.
Biomaterials 2011;32(15):3794-806.
2011: Pranabesh Dutta; Joykrishna Dey; Venkatesan Perumal; Mahitosh Mandal
Amino acid based amphiphilic copolymer micelles as carriers of non-steroidal anti-inflammatory drugs: solubilization, in vitro release and biological evaluation.
International journal of pharmaceutics 2011;407(1-2):207-16.
2011: Sarmistha Talukdar; Mahitosh Mandal; Dietmar W Hutmacher; Pamela J Russell; Carolina Soekmadji; Subhas C. Kundu
Engineered silk fibroin protein 3D matrices for in vitro tumor model.
Biomaterials 2011;32(8):2149-59.
2011: Siddik Sarkar; Abhijit Mazumdar; Rupesh Dash; Devanand Sarkar; Paul B Fisher; Mahitosh Mandal
ZD6474 enhances paclitaxel antiproliferative and apoptotic effects in breast carcinoma cells.
Journal of cellular physiology 2011;226(2):375-84.
2011: Kruttibas Sethi; Subhasis Das; Adel K El-Naggar; Abhijit Mazumder; Biswanarayan Mohanty; Susmita Patra; Shashi Rajput; Bhaskar Roy; Siddik Sarkar; Mahitosh Mandal
Expressions of CK-19, NF-kappaB, E-cadherin, beta-catenin and EGFR as diagnostic and prognostic markers by immunohistochemical analysis in thyroid carcinoma.
Journal of experimental therapeutics & oncology 2011;9(3):187-99.
2010: Saravana Kumar Jaganathan; Mahitosh Mandal
Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis.
Investigational new drugs 2010;28(5):624-33.
2010: Saravana Kumar Jaganathan; Mandal Santi; Saikat Kumar Jana; Soumen Das; Mahitosh Mandal
Studies on the phenolic profiling, anti-oxidant and cytotoxic activity of Indian honey: in vitro evaluation.
Natural product research 2010;24(14):1295-306.
2010: A Sureshkumar; R Sankar; Mahitosh Mandal; Sudarsan Neogi
Effective bacterial inactivation using low temperature radio frequency plasma.
International journal of pharmaceutics 2010;396(1-2):17-22.
2010: Siddik Sarkar; Abhijit Mazumdar; Rupesh Dash; Devanand Sarkar; Paul B Fisher; Mahitosh Mandal
ZD6474, a dual tyrosine kinase inhibitor of EGFR and VEGFR-2, inhibits MAPK/ERK and AKT/PI3-K and induces apoptosis in breast cancer cells.
Cancer biology & therapy 2010;9(8):592-603.
2010: P Venkatesan; Soumen Das; M Muthu Rama Krishnan; Chandan Chakraborty; Koel Chaudhury; Mahitosh Mandal
Effect of AEE788 and/or Celecoxib on colon cancer cell morphology using advanced microscopic techniques.
Micron (Oxford, England : 1993) 2010;41(3):247-56.
2010: Kruttibas Sethi; Siddik Sarkar; Subhasis Das; Biswanarayan Mohanty; Mahitosh Mandal
Biomarkers for the diagnosis of thyroid cancer.
Journal of experimental therapeutics & oncology 2010;8(4):341-52.
2010: Mandal Santi; Satyahari Dey; Mahitosh Mandal; Simone Maria-Neto; Octavio L Franco
Comparative analyses of different surfactants on matrix-assisted laser desorption/ionization mass spectrometry peptide analysis.
European journal of mass spectrometry (Chichester, England) 2010;16(5):567-75.
2010: Saravana Kumar Jaganathan; Dilip Mondhe; Z A Wani; Harish C Pal; Mahitosh Mandal
Effect of honey and eugenol on Ehrlich ascites and solid carcinoma.
Journal of biomedicine & biotechnology 2010;2010():989163.
2009: Mandal Santi; Mahitosh Mandal; Bikas R Pati; Amit K Das; Ananta K Ghosh
Proteomics view of a Rhizobium isolate response to arsenite [As(III)] stress.
Acta microbiologica et immunologica Hungarica 2009;56(2):157-67.
2009: Mandal Santi; Mahitosh Mandal; Ananta K Ghosh; Satyahari Dey
Rapid determination of vitamin B2 and B12 in human urine by isocratic liquid chromatography.
Analytica chimica acta 2009;640(1-2):110-3.
2009: Santi M Mandal; Santi Mandal; Mahitosh Mandal; Amit K Das; Amit Das; Bikas R Pati; Bikas Pati; Ananta K Ghosh; Ananta Ghosh
Stimulation of indoleacetic acid production in a Rhizobium isolate of Vigna mungo by root nodule phenolic acids.
Archives of microbiology 2009;191(4):389-93.
2009: Mandal Santi; Satyahari Dey; Mahitosh Mandal; Siddik Sarkar; Simone Maria-Neto; Octavio L Franco
Identification and structural insights of three novel antimicrobial peptides isolated from green coconut water.
Peptides 2009;30(4):633-7.
2009: Siddik Sarkar; Mahitosh Mandal
Growth factor receptors and apoptosis regulators: signaling pathways, prognosis, chemosensitivity and treatment outcomes of breast cancer.
Breast cancer : basic and clinical research 2009;3():47-60.
2009: Michael E Kupferman; Arumugam Jayakumar; Ge Zhou; Tong Xie; Yasemin Dakak-Yazici; Mei Zhao; Jun Ju; Mahitosh Mandal; Samar Jasser; Timothy Madden; Jeffrey N Myers; Waldemar Priebe
Therapeutic suppression of constitutive and inducible JAK\STAT activation in head and neck squamous cell carcinoma.
Journal of experimental therapeutics & oncology 2009;8(2):117-27.
2009: Saravana Kumar Jaganathan; Mahitosh Mandal
Antiproliferative effects of honey and of its polyphenols: a review.
Journal of biomedicine & biotechnology 2009;2009():830616.
2008: Mahitosh Mandal; Jeffery N Myers; Scott M Lippman; Faye M Johnson; Michelle D Williams; Suresh Rayala; Kazufumi Ohshiro; David I Rosenthal; Randal S Weber; Gary E Gallick; Adel K El-Naggar
Epithelial to mesenchymal transition in head and neck squamous carcinoma: association of Src activation with E-cadherin down-regulation, vimentin expression, and aggressive tumor features.
Cancer 2008;112(9):2088-100.
2007: Christopher N Prichard; Seungwon Kim; Yasemin D Yazici; Dao Doan; Samar A Jasser; Mahitosh Mandal; Jeffrey N Myers
Concurrent cetuximab and bevacizumab therapy in a murine orthotopic model of anaplastic thyroid carcinoma.
The Laryngoscope 2007;117(4):674-9.
2006: Seungwon Kim; Yasemin D Yazici; Samantha E Barber; Samar A Jasser; Mahitosh Mandal; B Nebiyou Bekele; Jeffrey N Myers
Growth inhibition of orthotopic anaplastic thyroid carcinoma xenografts in nude mice by PTK787/ZK222584 and CPT-11.
Head & neck 2006;28(5):389-99.
2006: Mahitosh Mandal; Maher N Younes; Eric A Swan; Samar A Jasser; Dao Doan; Orhan G Yigitbasi; Andrea McMurphey; James Ludwick; Adel K El-Naggar; Corazon D Bucana; Gordon B Mills; Jeffrey N Myers
The Akt inhibitor KP372-1 inhibits proliferation and induces apoptosis and anoikis in squamous cell carcinoma of the head and neck.
Oral oncology 2006;42(4):430-9.
2005: Maher N Younes; Seungwon Kim; Orhan G Yigitbasi; Mahitosh Mandal; Samar A Jasser; Yasemin Dakak Yazici; Bradley Schiff; Adel El-Naggar; B Nebiyou Bekele; Gordon B Mills; Jeffrey N Myers
Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer.
Molecular cancer therapeutics 2005;4(8):1146-56.
2005: Maher N Younes; Orhan G Yigitbasi; Young Wook Park; Sun-Jin Kim; Samar A Jasser; Valerie Stone Hawthorne; Yasemin D Yazici; Mahitosh Mandal; B Nebiyou Bekele; Corazon D Bucana; Isaiah J Fidler; Jeffrey N Myers
Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation.
Cancer research 2005;65(11):4716-27.
2005: Mahitosh Mandal; S Kim; Maher N Younes; Samar A Jasser; Adel K El-Naggar; Gordon B Mills; Jeffrey N Myers
The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells.
British journal of cancer 2005;92(10):1899-905.
2005: Seungwon Kim; Bradley Schiff; Orhan G Yigitbasi; Dao Doan; Samar A Jasser; B Nebiyou Bekele; Mahitosh Mandal; Jeffrey N Myers
Targeted molecular therapy of anaplastic thyroid carcinoma with AEE788.
Molecular cancer therapeutics 2005;4(4):632-40.
2005: Seungwon Kim; Young-Wook Park; Bradley Schiff; Dao Doan; Yasemin D Yazici; Samar A Jasser; Maher N Younes; Mahitosh Mandal; B Nebiyou Bekele; Jeffrey N Myers
An orthotopic model of anaplastic thyroid carcinoma in athymic nude mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(5):1713-21.
2004: Bradley Schiff; Andrea B McMurphy; Samar A Jasser; Maher N Younes; Dao Doan; Orhan G Yigitbasi; Seungwon Kim; Ge Zhou; Mahitosh Mandal; B Nebiyou Bekele; F Christopher Holsinger; Steven I Sherman; Sai-Ching Jim Yeung; Adel K El-Naggar; Jeffrey N Myers
Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8594-602.
2003: Christopher J Barnes; Rozita Bagheri-Yarmand; Mahitosh Mandal; Zhibo Yang; Gary L Clayman; Waun Ki Hong; Rakesh Kumar
Suppression of epidermal growth factor receptor, mitogen-activated protein kinase, and Pak1 pathways and invasiveness of human cutaneous squamous cancer cells by the tyrosine kinase inhibitor ZD1839 (Iressa).
Molecular cancer therapeutics 2003;2(4):345-51.
2003: Amjad H Talukder; Sandip K Mishra; Mahitosh Mandal; Seetharaman Balasenthil; Sonal Mehta; Aysegul A Sahin; Christopher J Barnes; Rakesh Kumar
MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions.
The Journal of biological chemistry 2003;278(13):11676-85.
2002: Rakesh Kumar; Rui-An Wang; Abhijit Mazumdar; Amjad H Talukder; Mahitosh Mandal; Zhibo Yang; Rozita Bagheri-Yarmand; Aysegul Sahin; Gabriel Hortobagyi; Liana Adam; Christopher J Barnes; Ratna K Vadlamudi
A naturally occurring MTA1 variant sequesters oestrogen receptor-alpha in the cytoplasm.
Nature 2002;418(6898):654-7.
2002: Feng Li; Liana Adam; Ratna K Vadlamudi; Hongyi Zhou; Subrata Sen; Jonathan Chernoff; Mahitosh Mandal; Rakesh Kumar
p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells.
EMBO reports 2002;3(8):767-73.
2002: Feng Li; Mahitosh Mandal; Sandip K Mishra; Christopher J Barnes; Rakesh Kumar
Heregulin promotes expression and subcellular redistribution of ADP-ribosylation factor 3.
FEBS letters 2002;524(1-3):49-53.
2002: Mahitosh Mandal; Feng Li; Rakesh Kumar
Heregulin up-regulates heat shock protein-70 expression in breast cancer cells.
Anticancer research 2002;22(4):1965-9.
2002: Christopher J Barnes; Feng Li; Mahitosh Mandal; Zhibo Yang; Aysegul A Sahin; Rakesh Kumar
Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors.
Cancer research 2002;62(5):1251-5.
2001: Feng Li; Mahitosh Mandal; Christopher J Barnes; Ratna K Vadlamudi; Rakesh Kumar
Growth factor regulation of the molecular chaperone calnexin.
Biochemical and biophysical research communications 2001;289(3):725-32.
2001: Sandip K Mishra; Mahitosh Mandal; Abhijit Mazumdar; Rakesh Kumar
Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells.
FEBS letters 2001;507(1):88-94.
2001: Rozita Bagheri-Yarmand; Mahitosh Mandal; A H Taludker; Rui-An Wang; Ratna K Vadlamudi; Hsing-Jien Kung; Rakesh Kumar
Etk/Bmx tyrosine kinase activates Pak1 and regulates tumorigenicity of breast cancer cells.
The Journal of biological chemistry 2001;276(31):29403-9.
2001: Mahitosh Mandal; Ratna K Vadlamudi; Diep Nguyen; Rui-An Wang; L Costa; Rozita Bagheri-Yarmand; John Mendelsohn; Rakesh Kumar
Growth factors regulate heterogeneous nuclear ribonucleoprotein K expression and function.
The Journal of biological chemistry 2001;276(13):9699-704.
2001: Amjad H Talukder; HF Jorgensen; Mahitosh Mandal; Sandip K Mishra; Ratna K Vadlamudi; Brian F C Clark; John Mendelsohn; Rakesh Kumar
Regulation of elongation factor-1alpha expression by growth factors and anti-receptor blocking antibodies.
The Journal of biological chemistry 2001;276(8):5636-42.
2001: Mahitosh Mandal; D J Olson; T Sharma; Ratna K Vadlamudi; Rakesh Kumar
Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells.
Gastroenterology 2001;120(1):71-8.
2001: Abhijit Mazumdar; Rui-An Wang; Sandip K Mishra; Liana Adam; Rozita Bagheri-Yarmand; Mahitosh Mandal; Ratna K Vadlamudi; Rakesh Kumar
Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor.
Nature cell biology 2001;3(1):30-7.
2000: Rakesh Kumar; Mahitosh Mandal; Ratna K Vadlamudi
New insights into anti-HER-2 receptor monoclonal antibody research.
Seminars in oncology 2000;27(6 Suppl 11):84-91; discussion 92-100.
2000: Ratna K Vadlamudi; Liana Adam; Rui-An Wang; Mahitosh Mandal; Diep Nguyen; Aysegul Sahin; Jonathan Chernoff; Mien-Chie Hung; Rakesh Kumar
Regulatable expression of p21-activated kinase-1 promotes anchorage-independent growth and abnormal organization of mitotic spindles in human epithelial breast cancer cells.
The Journal of biological chemistry 2000;275(46):36238-44.
2000: Liana Adam; Ratna K Vadlamudi; Mahitosh Mandal; Jonathan Chernoff; Rakesh Kumar
Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1.
The Journal of biological chemistry 2000;275(16):12041-50.
2000: Amjad H Talukder; Ratna K Vadlamudi; Mahitosh Mandal; Rakesh Kumar
Heregulin induces expression, DNA binding activity, and transactivating functions of basic leucine zipper activating transcription factor 4.
Cancer research 2000;60(2):276-81.
1999: Mahitosh Mandal; Liana Adam; Rakesh Kumar
Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis.
Biochemical and biophysical research communications 1999;260(3):775-80.
1999: Ratna K Vadlamudi; Mahitosh Mandal; Liana Adam; G Steinbach; John Mendelsohn; Rakesh Kumar
Regulation of cyclooxygenase-2 pathway by HER2 receptor.
Oncogene 1999;18(2):305-14.
1998: Mahitosh Mandal; Liana Adam; John Mendelsohn; Rakesh Kumar
Nuclear targeting of Bax during apoptosis in human colorectal cancer cells.
Oncogene 1998;17(8):999-1007.
1998: D Bandyopadhyay; Mahitosh Mandal; Liana Adam; John Mendelsohn; Rakesh Kumar
Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells.
The Journal of biological chemistry 1998;273(3):1568-73.
1998: Mahitosh Mandal; D Bandyopadhyay; T M Goepfert; Rakesh Kumar
Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK).
Oncogene 1998;16(2):217-25.
1997: Mahitosh Mandal; Rakesh Kumar
Bcl-2 modulates telomerase activity.
The Journal of biological chemistry 1997;272(22):14183-7.