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Hari Manev

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Svetlana Dzitoyeva; Hu Chen; Hari Manev
Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.
Hu Chen; Svetlana Dzitoyeva; Hari Manev
Effect of valproic acid on mitochondrial epigenetics.
Hu Chen; Svetlana Dzitoyeva; Hari Manev
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.

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All Publications

2012: Svetlana Dzitoyeva; Hu Chen; Hari Manev
Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.
Neurobiology of aging 2012;33(12):2881-91.
2012: Hu Chen; Svetlana Dzitoyeva; Hari Manev
Effect of valproic acid on mitochondrial epigenetics.
European journal of pharmacology 2012;690(1-3):51-9.
2012: Hu Chen; Svetlana Dzitoyeva; Hari Manev
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus.
Restorative neurology and neuroscience 2012;30(3):237-45.
2011: Hu Chen; Hari Manev
Effects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient mice.
Neuropharmacology 2011;60(7-8):1058-63.
2011: Hari Manev; Hu Chen; Svetlana Dzitoyeva; Radmila Manev
Cyclooxygenases and 5-lipoxygenase in Alzheimer's disease.
Progress in neuro-psychopharmacology & biological psychiatry 2011;35(2):315-9.
2010: H Chen; S Dzitoyeva; Hari Manev
5-Lipoxygenase in mouse cerebellar Purkinje cells.
Neuroscience 2010;171(2):383-9.
2010: Hari Manev; Radmila Manev
Benefits of neuropsychiatric phenomics: example of the 5-lipoxygenase-leptin-Alzheimer connection.
Cardiovascular psychiatry and neurology 2010;2010():838164.
2010: Hari Manev; Svetlana Dzitoyeva
GABA-B receptors in Drosophila.
Advances in pharmacology (San Diego, Calif.) 2010;58():453-64.
2010: Hari Manev
Cardiovascular-CNS Comorbidity as a Means to Rationalize Serendipity in Drug Discovery and Advance Translational Research.
Cardiovascular psychiatry and neurology 2010;2010():318167.
2009: Marta Imbesi; Svetlana Dzitoyeva; L W Ng; Hari Manev
5-Lipoxygenase and epigenetic DNA methylation in aging cultures of cerebellar granule cells.
Neuroscience 2009;164(4):1531-7.
2009: Hari Manev; Radmila Manev
Interactions with GluR1 AMPA receptors could influence the therapeutic usefulness of minocycline in ALS.
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2009;10(5-6):416-7.
2009: Hu Chen; Tolga Uz; Hari Manev
Minocycline affects cocaine sensitization in mice.
Neuroscience letters 2009;452(3):258-61.
2009: Radmila Manev; Hari Manev
Minocycline, schizophrenia and GluR1 glutamate receptors.
Progress in neuro-psychopharmacology & biological psychiatry 2009;33(1):166; author reply 167.
2009: Marta Imbesi; S Yildiz; A Dirim Arslan; Rajiv P Sharma; Hari Manev; Tolga Uz
Dopamine receptor-mediated regulation of neuronal "clock" gene expression.
Neuroscience 2009;158(2):537-44.
2009: Svetlana Dzitoyeva; Marta Imbesi; Louisa W Ng; Hari Manev
5-Lipoxygenase DNA methylation and mRNA content in the brain and heart of young and old mice.
Neural plasticity 2009;2009():209596.
2009: Hari Manev
The heart-brain connection begets cardiovascular psychiatry and neurology.
Cardiovascular psychiatry and neurology 2009;2009():546737.
2009: Hari Manev
Hypotheses on mechanisms linking cardiovascular and psychiatric/neurological disorders.
Cardiovascular psychiatry and neurology 2009;2009():197132.
2009: Hari Manev; Tolga Uz
Dosing time-dependent actions of psychostimulants.
International review of neurobiology 2009;88():25-41.
2009: Marta Imbesi; Ahmet Dirim Arslan; Sevim Yildiz; Rajiv P Sharma; David Peter Gavin; Nguwah Tun; Hari Manev; Tolga Uz
The melatonin receptor MT1 is required for the differential regulatory actions of melatonin on neuronal 'clock' gene expression in striatal neurons in vitro.
Journal of pineal research 2009;46(1):87-94.
2008: Marta Imbesi; Tolga Uz; Radmila Manev; Rajiv P Sharma; Hari Manev
Minocycline increases phosphorylation and membrane insertion of neuronal GluR1 receptors.
Neuroscience letters 2008;447(2-3):134-7.
2008: Milos D Ikonomovic; Eric Abrahamson; Tolga Uz; Hari Manev; Steven T DeKosky
Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008;56(12):1065-73.
2008: Marta Imbesi; Tolga Uz; Hari Manev
Role of melatonin receptors in the effects of melatonin on BDNF and neuroprotection in mouse cerebellar neurons.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(11):1495-9.
2008: Marta Imbesi; Tolga Uz; Hari Manev
Melatonin receptor agonist ramelteon activates the extracellular signal-regulated kinase 1/2 in mouse cerebellar granule cells.
Neuroscience 2008;155(4):1160-4.
2008: Marta Imbesi; Tolga Uz; Svetlana Dzitoyeva; Pietro Giusti; Hari Manev
Melatonin signaling in mouse cerebellar granule cells with variable native MT1 and MT2 melatonin receptors.
Brain research 2008;1227():19-25.
2008: Morena Zusso; Patrizia Debetto; Diego Guidolin; Massimo Barbierato; Hari Manev; Pietro Giusti
Fluoxetine-induced proliferation and differentiation of neural progenitor cells isolated from rat postnatal cerebellum.
Biochemical pharmacology 2008;76(3):391-403.
2008: Hari Manev; Radmila Manev
Pharmacological probing of type 1 autism.
Journal of autism and developmental disorders 2008;38(7):1400-1.
2008: Marta Imbesi; Tolga Uz; Svetlana Dzitoyeva; Hari Manev
Stimulatory effects of a melatonin receptor agonist, ramelteon, on BDNF in mouse cerebellar granule cells.
Neuroscience letters 2008;439(1):34-6.
2008: Svetlana Dzitoyeva; Marta Imbesi; Tolga Uz; Nikola Dimitrijevic; Hari Manev; Radmila Manev
Caffeic acid attenuates the decrease of cortical BDNF transcript IV mRNA induced by swim stress in wild-type but not in 5-lipoxygenase-deficient mice.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(6):823-7.
2008: Hari Manev; Radmila Manev; Mladen Vidovich
Depression, inflammation, and cardiovascular disease: is 5-lipoxygenase the missing link?
Journal of the American College of Cardiology 2008;51(20):1990-1; author reply 1991.
2008: Tolga Uz; Nikola Dimitrijevic; Marta Imbesi; Hari Manev; Radmila Manev
Effects of MK-886, a 5-lipoxygenase activating protein (FLAP) inhibitor, and 5-lipoxygenase deficiency on the forced swimming behavior of mice.
Neuroscience letters 2008;436(2):269-72.
2008: Murat Kurtuncu; N Battista; Tolga Uz; A D'Agostino; Nikola Dimitrijevic; N Pasquariello; Radmila Manev; Mauro Maccarrone; Hari Manev
Effects of cocaine in 5-lipoxygenase-deficient mice.
Journal of neural transmission (Vienna, Austria : 1996) 2008;115(3):389-95.
2007: Hari Manev; Radmila Manev
5-lipoxygenase as a possible biological link between depressive symptoms and atherosclerosis.
Archives of general psychiatry 2007;64(11):1333.
2007: Marta Imbesi; Iris Zavoreo; Tolga Uz; Rajiv P Sharma; Nikola Dimitrijevic; Hari Manev; Radmila Manev
5-Lipoxygenase inhibitor MK-886 increases GluR1 phosphorylation in neuronal cultures in vitro and in the mouse cortex in vivo.
Brain research 2007;1147():148-53.
2007: Radmila Manev; Danijela Mrazovac; Hari Manev
Possible role for interactions between 5-lipoxygenase (5-LOX) and AMPA GluR1 receptors in depression and in antidepressant therapy.
Medical hypotheses 2007;69(5):1076-9.
2007: Eric Hirsch-Rodriguez; Marta Imbesi; Radmila Manev; Tolga Uz; Hari Manev
The pattern of melatonin receptor expression in the brain may influence antidepressant treatment.
Medical hypotheses 2007;69(1):120-4.
2006: Hari Manev; Radmila Manev
Olanzapine and S100 proteins.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(11):2567; author reply 2568-9.
2006: Hari Manev; Tolga Uz
Clock genes: influencing and being influenced by psychoactive drugs.
Trends in pharmacological sciences 2006;27(4):186-9.
2006: John Larson; Ruth E Jessen; Tolga Uz; Ahmet D Arslan; Murat Kurtuncu; Marta Imbesi; Hari Manev
Impaired hippocampal long-term potentiation in melatonin MT2 receptor-deficient mice.
Neuroscience letters 2006;393(1):23-6.
2006: Radmila Manev; Hari Manev
Could treatment with arundic acid (ONO-2506) increase vulnerability for depression?
Medical hypotheses 2006;67(5):1170-2.
2006: Hari Manev; Radmila Manev
Nomen est Omen: do antidepressants increase p11 or S100A10?
Journal of biomedical discovery and collaboration 2006;1():5.
2006: Hari Manev; Tolga Uz
Clock genes as a link between addiction and obesity.
European journal of human genetics : EJHG 2006;14(1):5.
2006: Hari Manev; Radmila Manev
5-Lipoxygenase (ALOX5) and FLAP (ALOX5AP) gene polymorphisms as factors in vascular pathology and Alzheimer's disease.
Medical hypotheses 2006;66(3):501-3.
2005: Murat Kurtuncu; Lance J Luka; Nikola Dimitrijevic; Tolga Uz; Hari Manev
Reliability assessment of an automated forced swim test device using two mouse strains.
Journal of neuroscience methods 2005;149(1):26-30.
2005: Nikola Dimitrijevic; Svetlana Dzitoyeva; Rosalba Satta; Marta Imbesi; Sevim Yildiz; Hari Manev
Drosophila GABA(B) receptors are involved in behavioral effects of gamma-hydroxybutyric acid (GHB).
European journal of pharmacology 2005;519(3):246-52.
2005: Svetlana Dzitoyeva; Alan Gutnov; Marta Imbesi; Nikola Dimitrijevic; Hari Manev
Developmental role of GABAB(1) receptors in Drosophila.
Brain research. Developmental brain research 2005;158(1-2):111-4.
2005: Tolga Uz; Ahmet D Arslan; Murat Kurtuncu; Marta Imbesi; Mustafa Akhisaroglu; Yogesh Dwivedi; Ghanshyam N Pandey; Hari Manev
The regional and cellular expression profile of the melatonin receptor MT1 in the central dopaminergic system.
Brain research. Molecular brain research 2005;136(1-2):45-53.
2005: Hari Manev; Nikola Dimitrijevic
Fruit flies for anti-pain drug discovery.
Life sciences 2005;76(21):2403-7.
2005: Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Ethanol injections in Drosophila.
Alcoholism, clinical and experimental research 2005;29(4):692; author reply 692.
2005: Mustafa Akhisaroglu; Murat Kurtuncu; Hari Manev; Tolga Uz
Diurnal rhythms in quinpirole-induced locomotor behaviors and striatal D2/D3 receptor levels in mice.
Pharmacology, biochemistry, and behavior 2005;80(3):371-7.
2005: Hari Manev; Radmila Manev
Possible genetic predisposition to cardiac effects.
The Medical journal of Australia 2005;182(4):198; author reply 199.
2005: Tolga Uz; Rehan Ahmed; Mustafa Akhisaroglu; Murat Kurtuncu; Marta Imbesi; A Dirim Arslan; Hari Manev
Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum.
Neuroscience 2005;134(4):1309-16.
2005: Radmila Manev; Hari Manev
5-Lipoxygenase as a putative mechanism of NSAID-related psychiatric adverse events.
Drugs 2005;65(4):577.
2005: Radmila Manev; Hari Manev
The meaning of mammalian adult neurogenesis and the function of newly added neurons: the "small-world" network.
Medical hypotheses 2005;64(1):114-7.
2004: Zhijing Zhang; Chang-qing Chen; Hari Manev
Enzymatic regional methylation assay for determination of CpG methylation density.
Analytical chemistry 2004;76(22):6829-32.
2004: Mustafa Akhisaroglu; Rehan Ahmed; Murat Kurtuncu; Hari Manev; Tolga Uz
Diurnal rhythms in cocaine sensitization and in Period1 levels are common across rodent species.
Pharmacology, biochemistry, and behavior 2004;79(1):37-42.
2004: Nikola Dimitrijevic; Svetlana Dzitoyeva; Hari Manev
An automated assay of the behavioral effects of cocaine injections in adult Drosophila.
Journal of neuroscience methods 2004;137(2):181-4.
2004: Hari Manev; Nikola Dimitrijevic
Drosophila model for in vivo pharmacological analgesia research.
European journal of pharmacology 2004;491(2-3):207-8.
2004: Murat Kurtuncu; Ahmet D Arslan; Mustafa Akhisaroglu; Hari Manev; Tolga Uz
Involvement of the pineal gland in diurnal cocaine reward in mice.
European journal of pharmacology 2004;489(3):203-5.
2004: Tolga Uz; Nikola Dimitrijevic; Mustafa Akhisaroglu; Marta Imbesi; Murat Kurtuncu; Hari Manev
The pineal gland and anxiogenic-like action of fluoxetine in mice.
Neuroreport 2004;15(4):691-4.
2004: Zhijing Zhang; Chang-qing Chen; Hari Manev
DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells.
Journal of neurochemistry 2004;88(6):1424-30.
2004: Radmila Manev; Hari Manev
5-Lipoxygenase as a putative link between cardiovascular and psychiatric disorders.
Critical reviews in neurobiology 2004;16(1-2):181-6.
2003: Tolga Uz; Mustafa Akhisaroglu; Rehan Ahmed; Hari Manev
The pineal gland is critical for circadian Period1 expression in the striatum and for circadian cocaine sensitization in mice.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(12):2117-23.
2003: Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Identification of a novel Drosophila gene, beltless, using injectable embryonic and adult RNA interference (RNAi).
BMC genomics 2003;4(1):33.
2003: Mustafa Akhisaroglu; Radmila Manev; Ezgi Akhisaroglu; Tolga Uz; Hari Manev
Both aging and chronic fluoxetine increase S100B content in the mouse hippocampus.
Neuroreport 2003;14(11):1471-3.
2003: Rosalba Satta; Nikola Dimitrijevic; Hari Manev
Drosophila metabolize 1,4-butanediol into gamma-hydroxybutyric acid in vivo.
European journal of pharmacology 2003;473(2-3):149-52.
2003: Emre Yildirim; Zhijing Zhang; Tolga Uz; Chang-qing Chen; Radmila Manev; Hari Manev
Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus.
Neuroscience letters 2003;345(2):141-3.
2003: Hari Manev; Tolga Uz; Radmila Manev
Glia as a putative target for antidepressant treatments.
Journal of affective disorders 2003;75(1):59-64.
2003: Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Gamma-aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5485-90.
2003: Hari Manev; Nikola Dimitrijevic; Svetlana Dzitoyeva
Techniques: fruit flies as models for neuropharmacological research.
Trends in pharmacological sciences 2003;24(1):41-3.
2002: Giorgia Miolo; Sergio Caffieri; Laura Levorato; Marta Imbesi; Pietro Giusti; Tolga Uz; Radmila Manev; Hari Manev
Photoisomerization of fluvoxamine generates an isomer that has reduced activity on the 5-hydroxytryptamine transporter and does not affect cell proliferation.
European journal of pharmacology 2002;450(3):223-9.
2002: Hari Manev; Tolga Uz
DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA.
European journal of pharmacology 2002;445(1-2):149-50.
2002: Tolga Uz; Javaid I Javaid; Hari Manev
Circadian differences in behavioral sensitization to cocaine: putative role of arylalkylamine N-acetyltransferase.
Life sciences 2002;70(25):3069-75.
2002: Hari Manev; Svetlana Dzitoyeva; Nikola Dimitrijevic
The human genome: gene silencing.
The American journal of psychiatry 2002;159(5):720.
2002: Tolga Uz; Tingyu Qu; Kiminobu Sugaya; Hari Manev
Neuronal expression of arylalkylamine N-acetyltransferase (AANAT) mRNA in the rat brain.
Neuroscience research 2002;42(4):309-16.
2002: Ersin O Koylu; Tolga Uz; Hari Manev; Sakire Pogun
Nitric oxide synthase inhibition suppresses wet dog shakes and augments convulsions in rats.
The International journal of neuroscience 2002;112(3):291-300.
2002: Tolga Uz; Nikola Dimitrijevic; Patricia Tueting; Hari Manev
5-lipoxygenase (5LOX)-deficient mice express reduced anxiety-like behavior.
Restorative neurology and neuroscience 2002;20(1-2):15-20.
2002: Hari Manev; Radmila Manev
New antidepressant drugs that do not cross the blood-brain barrier.
Medical hypotheses 2002;58(1):83-4.
2001: Hari Manev; Radmila Manev
S100B: an old neurotrophic factor with putative new roles in psychiatric illnesses.
Journal of psychiatric research 2001;35(6):347-50.
2001: Svetlana Dzitoyeva; Nikola Dimitrijevic; Hari Manev
Intra-abdominal injection of double-stranded RNA into anesthetized adult Drosophila triggers RNA interference in the central nervous system.
Molecular psychiatry 2001;6(6):665-70.
2001: Tolga Uz; Yogesh Dwivedi; A Qeli; Marc Peters-Golden; Ghanshyam N Pandey; Hari Manev
Glucocorticoid receptors are required for up-regulation of neuronal 5-lipoxygenase (5LOX) expression by dexamethasone.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1792-4.
2001: Hari Manev; Tolga Uz; Radmila Manev; Zhijing Zhang
Neurogenesis and neuroprotection in the adult brain. A putative role for 5-lipoxygenase?
Annals of the New York Academy of Sciences 2001;939():45-51.
2001: Radmila Manev; Tolga Uz; Hari Manev
Fluoxetine increases the content of neurotrophic protein S100beta in the rat hippocampus.
European journal of pharmacology 2001;420(2-3):R1-2.
2001: Tolga Uz; Radmila Manev; Hari Manev
5-Lipoxygenase is required for proliferation of immature cerebellar granule neurons in vitro.
European journal of pharmacology 2001;418(1-2):15-22.
2001: Tolga Uz; Hari Manev
Prolonged swim-test immobility of serotonin N-acetyltransferase (AANAT)-mutant mice.
Journal of pineal research 2001;30(3):166-70.
2001: Neil R Smalheiser; Hari Manev; Erminio Costa
RNAi and brain function: was McConnell on the right track?
Trends in neurosciences 2001;24(4):216-8.
2001: Hari Manev; Tolga Uz; Neil R Smalheiser; Radmila Manev
Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.
European journal of pharmacology 2001;411(1-2):67-70.
2001: Radmila Manev; Hari Manev
Aminoglycoside antibiotics and autism: a speculative hypothesis.
BMC psychiatry 2001;1():5.
2001: Alejandro M S Mayer; M Hall; Michael Fay; Peter C Lamar; C Pearson; Walter C Prozialeck; V K Lehmann; PB Jacobson; A M Romanic; T Uz; Hari Manev
Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia.
BMC pharmacology 2001;1():7.
2001: Tingyu Qu; Radmila Manev; Hari Manev
5-Lipoxygenase (5-LOX) promoter polymorphism in patients with early-onset and late-onset Alzheimer's disease.
The Journal of neuropsychiatry and clinical neurosciences 2001;13(2):304-5.
2000: Hari Manev; Tolga Uz; Tingyu Qu
5-Lipoxygenase and cyclooxygenase mRNA expression in rat hippocampus:early response to glutamate receptor activation by kainate.
Experimental gerontology 2000;35(9-10):1201-9.
2000: Tingyu Qu; Tolga Uz; Hari Manev
Inflammatory 5-LOX mRNA and protein are increased in brain of aging rats.
Neurobiology of aging 2000;21(5):647-52.
2000: Hari Manev; Tolga Uz; Kiminobu Sugaya; Tingyu Qu
Putative role of neuronal 5-lipoxygenase in an aging brain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(10):1464-9.
2000: Kiminobu Sugaya; Tolga Uz; V Kumar; Hari Manev
New anti-inflammatory treatment strategy in Alzheimer's disease.
Japanese journal of pharmacology 2000;82(2):85-94.
2000: Hari Manev
5-Lipoxygenase gene polymorphism and onset of Alzheimer's disease.
Medical hypotheses 2000;54(1):75-6.
1999: Tolga Uz; Yogesh Dwivedi; P D Savani; F Impagnatiello; Ghanshyam N Pandey; Hari Manev
Glucocorticoids stimulate inflammatory 5-lipoxygenase gene expression and protein translocation in the brain.
Journal of neurochemistry 1999;73(2):693-9.
1999: Tolga Uz; Hari Manev
Chronic fluoxetine administration increases the serotonin N-acetyltransferase messenger RNA content in rat hippocampus.
Biological psychiatry 1999;45(2):175-9.
1999: Hari Manev; Tolga Uz
Primary cultures of rat cerebellar granule cells as a model to study neuronal 5-lipoxygenase and FLAP gene expression.
Annals of the New York Academy of Sciences 1999;890():183-90.
1998: Hari Manev; Tolga Uz
Oral melatonin in neurologically disabled children.
Lancet 1998;351(9120):1963; author reply 1964.
1998: Hari Manev; Tolga Uz; Tingyu Qu
Early upregulation of hippocampal 5-lipoxygenase following systemic administration of kainate to rats.
Restorative neurology and neuroscience 1998;12(2-3):81-5.
1998: Hari Manev; Erminio Costa; Joseph A Flaherty
Restorative neurology and neuroscience. Preface.
Restorative neurology and neuroscience 1998;12(2-3):57-8.
1998: Hari Manev; Tolga Uz
The role of the light-dark cycle and melatonin in stroke outcome.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 1998;7(3):165-7.
1998: Tolga Uz; Christine Pesold; P Longone; Hari Manev
Aging-associated up-regulation of neuronal 5-lipoxygenase expression: putative role in neuronal vulnerability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(6):439-49.
1998: Tolga Uz; Hari Manev
Circadian expression of pineal 5-lipoxygenase mRNA.
Neuroreport 1998;9(5):783-6.
1998: Jin Yang Joo; T Uz; Hari Manev
Opposite effects of pinealectomy and melatonin administration on brain damage following cerebral focal ischemia in rat.
Restorative neurology and neuroscience 1998;13(3-4):185-91.
1997: Tolga Uz; P Longone; Hari Manev
Increased hippocampal 5-lipoxygenase mRNA content in melatonin-deficient, pinealectomized rats.
Journal of neurochemistry 1997;69(5):2220-3.
1997: Hari Manev; Tolga Uz; Pietro Giusti
Neuroprotective action of the pineal hormone melatonin against excitotoxicity. Receptor abuse-dependent antagonism (RADA).
Annals of the New York Academy of Sciences 1997;825():85-9.
1997: Pietro Giusti; M Lipartiti; Milena Gusella; Maura Floreani; Hari Manev
In vitro and in vivo protective effects of melatonin against glutamate oxidative stress and neurotoxicity.
Annals of the New York Academy of Sciences 1997;825():79-84.
1997: S Ikonomovic; Elena A Kharlamov; Hari Manev; Milos D Ikonomovic; Dennis Grayson
GABA and NMDA in the prevention of apoptotic-like cell death in vitro.
Neurochemistry international 1997;31(2):283-90.
1997: Hari Manev; C M Cagnoli
Ceramide-mediated and isoquinolinesulfonamide-sensitive pathways of neuronal death: anything in common?
Neurochemistry international 1997;31(2):203-6.
1997: Hari Manev; Elena A Kharlamov; Tolga Uz; R P Mason; C M Cagnoli
Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells.
Experimental neurology 1997;146(1):171-8.
1997: A Kharlamov; Jin Yang Joo; T Uz; Hari Manev
Cycloheximide reduces the size of lesion caused in rats by a photothrombotic model of brain injury.
Neurological research 1997;19(1):92-6.
1996: Hari Manev; Tolga Uz; A Kharlamov; Jin Yang Joo
Increased brain damage after stroke or excitotoxic seizures in melatonin-deficient rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(13):1546-51.
1996: D Pericić; Hari Manev; Maja Bujas-Bobanovic
Gonadal hormones and picrotoxin-induced convulsions in male and female rats.
Brain research 1996;736(1-2):174-9.
1996: A Kharlamov; Tolga Uz; Jin Yang Joo; Hari Manev
Pharmacological characterization of apoptotic cell death in a model of photothrombotic brain injury in rats.
Brain research 1996;734(1-2):1-9.
1996: Tolga Uz; Pietro Giusti; Davide Franceschini; A Kharlamov; Hari Manev
Protective effect of melatonin against hippocampal DNA damage induced by intraperitoneal administration of kainate to rats.
Neuroscience 1996;73(3):631-6.
1996: Pietro Giusti; M Lipartiti; Davide Franceschini; N Schiavo; Maura Floreani; Hari Manev
Neuroprotection by melatonin from kainate-induced excitotoxicity in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(8):891-6.
1996: Pietro Giusti; Davide Franceschini; M Petrone; Hari Manev; Maura Floreani
In vitro and in vivo protection against kainate-induced excitotoxicity by melatonin.
Journal of pineal research 1996;20(4):226-31.
1996: C Atabay; C M Cagnoli; Elena A Kharlamov; Milos D Ikonomovic; Hari Manev
Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: protection with antioxidants and glutamate receptor antagonists.
Journal of neuroscience research 1996;43(4):465-75.
1996: Hari Manev; T Uz; A Kharlamov; C M Cagnoli; D Franceschini; P Giusti
In vivo protection against kainate-induced apoptosis by the pineal hormone melatonin: effect of exogenous melatonin and circadian rhythm.
Restorative neurology and neuroscience 1996;9(4):251-6.
1996: Hari Manev; T Uz; A Kharlamov; C M Cagnoli; D Franceschini; P Giusti
Corrigendum to "In vivo protection against kainate-induced apoptosis by the pineal hormone melatonin: effect of exogenous melatonin and circadian rhythm" [Restor. Neurol. Neurosci. 9 (1996) 251].
Restorative neurology and neuroscience 1996;10(2):121.
1996: M Lipartiti; Davide Franceschini; R Zanoni; Milena Gusella; Pietro Giusti; C M Cagnoli; A Kharlamov; Hari Manev
Neuroprotective effects of melatonin.
Advances in experimental medicine and biology 1996;398():315-21.
1996: C M Cagnoli; Elena A Kharlamov; C Atabay; Tolga Uz; Hari Manev
Apoptosis induced in neuronal cultures by either the phosphatase inhibitor okadaic acid or the kinase inhibitor staurosporine is attenuated by isoquinolinesulfonamides H-7, H-8, and H-9.
Journal of molecular neuroscience : MN 1996;7(1):65-76.
1996: C M Cagnoli; C Atabay; Hari Manev
Protective action of isoquinolinesulfonamides in in vitro models of neuronal apoptosis.
Life sciences 1996;58(19):PL295-301.
1995: Elena A Kharlamov; C M Cagnoli; C Atabay; S Ikonomović; Dennis Grayson; Hari Manev
Opposite effect of protein synthesis inhibitors on potassium deficiency-induced apoptotic cell death in immature and mature neuronal cultures.
Journal of neurochemistry 1995;65(3):1395-8.
1995: Hari Manev; C M Cagnoli; C Atabay; Elena A Kharlamov; M D Ikonomović; Dennis Grayson
Neuronal apoptosis in an in vitro model of photochemically induced oxidative stress.
Experimental neurology 1995;133(2):198-206.
1995: C M Cagnoli; C Atabay; E Kharlamova; Hari Manev
Melatonin protects neurons from singlet oxygen-induced apoptosis.
Journal of pineal research 1995;18(4):222-6.
1995: Pietro Giusti; Milena Gusella; M Lipartiti; D Milani; W Zhu; Stefano Vicini; Hari Manev
Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity.
Experimental neurology 1995;131(1):39-46.
1994: Hari Manev; A Kharlamov; D M Armstrong
Photochemical brain injury in rats triggers DNA fragmentation, p53 and HSP72.
Neuroreport 1994;5(18):2661-4.
1994: R Siliprandi; M Lipartiti; E Fadda; R Arban; Alan P Kozikowski; Hari Manev
A derivative of a rigid glutamate analog protects the retina from excitotoxicity.
Neuroreport 1994;5(10):1227-9.
1994: N Gabellini; Radmila Manev; Hari Manev
Is the heterologous expression of metabotropic glutamate receptors (mGluRs) an appropriate method to study the mGluR function? Experience with human embryonic kidney 293 cells transfected with mGluR1.
Neurochemistry international 1994;24(6):533-9.
1994: A Lazzaro; M S Seren; T Koga; R Zanoni; N Schiavo; Hari Manev
GM1 reduces infarct volume after focal cerebral ischemia.
Experimental neurology 1994;125(2):278-85.
1994: M S Seren; A Lazzaro; C L Yang; R Canella; M Bassan; R Zanoni; Hari Manev
Orally administered glycolipid derivative LIGA20 reduces infarct volume and behavioral impairment after focal cerebral ischemia.
The Journal of pharmacology and experimental therapeutics 1994;268(1):460-5.
1994: Erminio Costa; D M Armstrong; Alessandro Guidotti; A Kharlamov; Lech Kiedrowski; Hari Manev; A Polo; Jarda T Wroblewski
Gangliosides in the protection against glutamate excitotoxicity.
Progress in brain research 1994;101():357-73.
1993: Stephen Skaper; E Fadda; Laura Facci; Hari Manev
A semisynthetic glycosphingolipid (LIGA20) reduces 2,4, 5-trihydroxyphenylalanine neurotoxicity in primary neuronal cultures.
European journal of pharmacology 1993;243(1):91-3.
1993: Hari Manev; M Favaron; P Candeo; E Fadda; M Lipartiti; D Milani
Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate.
Brain research 1993;624(1-2):331-5.
1993: Alan P Kozikowski; Werner Tückmantel; Y Liao; Hari Manev; S Ikonomovic; Jarda T Wroblewski
Synthesis and metabotropic receptor activity of the novel rigidified glutamate analogues (+)- and (-)-trans-azetidine-2,4-dicarboxylic acid and their N-methyl derivatives.
Journal of medicinal chemistry 1993;36(18):2706-8.
1993: M Favaron; Radmila Manev; J M Rimland; P Candeo; M Beccaro; Hari Manev
NMDA-stimulated expression of BDNF mRNA in cultured cerebellar granule neurones.
Neuroreport 1993;4(10):1171-4.
1993: M Favaron; Radmila Manev; P Candeo; R Arban; N Gabellini; Alan P Kozikowski; Hari Manev
Trans-azetidine-2,4-dicarboxylic acid activates neuronal metabotropic receptors.
Neuroreport 1993;4(7):967-70.
1993: M C Comelli; D Guidolin; M S Seren; R Zanoni; R Canella; R Rubini; Hari Manev
Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke.
Neuroscience 1993;55(2):473-90.
1993: Radmila Manev; N Gabellini; Hari Manev
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
Neuroreport 1993;4(6):830-2.
1993: Radmila Manev; M Favaron; N Gabellini; P Candeo; Hari Manev
Functional evidence for a L-AP3-sensitive metabotropic receptor different from glutamate metabotropic receptor mGluR1.
Neuroscience letters 1993;155(1):73-6.
1993: N Gabellini; Radmila Manev; P Candeo; M Favaron; Hari Manev
Carboxyl domain of glutamate receptor directs its coupling to metabolic pathways.
Neuroreport 1993;4(5):531-4.
1993: G Lombardi; A M Szekely; L A Bristol; Alessandro Guidotti; Hari Manev
Induction of ornithine decarboxylase by N-methyl-D-aspartate receptor activation is unrelated to potentiation of glutamate excitotoxicity by polyamines in cerebellar granule neurons.
Journal of neurochemistry 1993;60(4):1317-24.
1993: M Lipartiti; E Fadda; G Savoini; R Siliprandi; Jürgen Sautter; R Arban; Hari Manev
In rats, the metabotropic glutamate receptor-triggered hippocampal neuronal damage is strain-dependent.
Life sciences 1993;52(10):PL85-90.
1993: Hari Manev; Alessandro Guidotti; Erminio Costa
Protection by gangliosides against glutamate excitotoxicity.
Advances in lipid research 1993;25():269-88.
1993: D Milani; P Candeo; M Favaron; C D Blackstone; Hari Manev
A subpopulation of cerebellar granule neurons in culture expresses a functional mGluR1 metabotropic glutamate receptor: effect of depolarizing growing conditions.
Receptors & channels 1993;1(3):243-50.
1992: Hari Manev
Experimental therapy of acute brain neurodegeneration.
Minerva anestesiologica 1992;58(10):935-6.
1992: M Lipartiti; A Lazzaro; Hari Manev
Ganglioside derivative LIGA20 reduces NMDA neurotoxicity in neonatal rat brain.
Neuroreport 1992;3(10):919-21.
1992: P Candeo; M Favaron; Imre Lengyel; Radmila Manev; J M Rimland; Hari Manev
Pathological phosphorylation causes neuronal death: effect of okadaic acid in primary culture of cerebellar granule cells.
Journal of neurochemistry 1992;59(4):1558-61.
1992: R Siliprandi; M Lipartiti; E Fadda; Jürgen Sautter; Hari Manev
Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity.
European journal of pharmacology 1992;219(1):173-4.
1992: M C Comelli; M S Seren; D Guidolin; Radmila Manev; M Favaron; J M Rimland; R Canella; Alessandro Negro; Hari Manev
Photochemical stroke and brain-derived neurotrophic factor (BDNF) mRNA expression.
Neuroreport 1992;3(6):473-6.
1992: M Favaron; J M Rimland; Hari Manev
Depolarization- and agonist-regulated expression of neuronal metabotropic glutamate receptor 1 (mGluR1).
Life sciences 1992;50(22):PL189-94.
1991: Lech Kiedrowski; Hari Manev; Erminio Costa; Jarda T Wroblewski
Inhibition of glutamate-induced cell death by sodium nitroprusside is not mediated by nitric oxide.
Neuropharmacology 1991;30(11):1241-3.
1991: Hari Manev; M Favaron; R Siman; Alessandro Guidotti; Erminio Costa
Glutamate neurotoxicity is independent of calpain I inhibition in primary cultures of cerebellar granule cells.
Journal of neurochemistry 1991;57(4):1288-95.
1991: Hari Manev; S Caredda; Dennis Grayson
Nonselective inhibition by antisense oligonucleotides of cytosine arabinoside action.
Neuroreport 1991;2(10):589-92.
1990: Hari Manev; M Bertolino; G DeErausquin
Amiloride blocks glutamate-operated cationic channels and protects neurons in culture from glutamate-induced death.
Neuropharmacology 1990;29(12):1103-10.
1990: Gabriel de Erausquin; Hari Manev; Alessandro Guidotti; Erminio Costa; Gary Brooker
Gangliosides normalize distorted single-cell intracellular free Ca2+ dynamics after toxic doses of glutamate in cerebellar granule cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8017-21.
1990: Hari Manev; Erminio Costa; Jarda T Wroblewski; Alessandro Guidotti
Abusive stimulation of excitatory amino acid receptors: a strategy to limit neurotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(10):2789-97.
1990: M Favaron; Hari Manev; R Siman; M Bertolino; A M Szekely; G DeErausquin; Alessandro Guidotti; Erminio Costa
Down-regulation of protein kinase C protects cerebellar granule neurons in primary culture from glutamate-induced neuronal death.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1983-7.
1990: Hari Manev; M Favaron; G De Erausquin; Alessandro Guidotti; Gary Brooker; Erminio Costa
Destabilization of ionized Ca2+ homeostasis in excitatory amino acid neurotoxicity: antagonism by glycosphingolipids.
Cell biology international reports 1990;14(1):3-14.
1990: D Pericić; Hari Manev
Dual species dependent effect of dihydroergosine on the convulsions induced by GABA antagonists.
Journal of neural transmission. General section 1990;79(1-2):125-9.
1990: Hari Manev; M Favaron; Stefano Vicini; Alessandro Guidotti
Ganglioside-mediated protection from glutamate-induced neuronal death.
Acta neurobiologiae experimentalis 1990;50(4-5):475-88.
1990: Alessandro Guidotti; Hari Manev; M Favaron; Gary Brooker; Erminio Costa
Protection by natural and semisynthetic gangliosides from Ca2(+)-dependent neurotoxicity caused by excitatory amino acid (EAA) neurotransmitters.
Advances in experimental medicine and biology 1990;268():135-44.
1990: M Boranić; D Pericić; M Poljak-Blazi; Hari Manev; Visnja Sverko; J Gabrilovac; M Radacić; Nela Pivac; G Miljenović
Immune response of stressed rats treated with drugs affecting serotoninergic and adrenergic transmission.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1990;44(7):381-7.
1990: Hari Manev; M Favaron; Stefano Vicini; Alessandro Guidotti; Erminio Costa
Glutamate-induced neuronal death in primary cultures of cerebellar granule cells: protection by synthetic derivatives of endogenous sphingolipids.
The Journal of pharmacology and experimental therapeutics 1990;252(1):419-27.
1989: Hari Manev; M Favaron; Alessandro Guidotti; Erminio Costa
Delayed increase of Ca2+ influx elicited by glutamate: role in neuronal death.
Molecular pharmacology 1989;36(1):106-12.
1989: Hari Manev; D Pericić; Dorotea Mück-Seler
Inhibitory influence of dihydroergosine on the aggressiveness of rats and mice.
Pharmacology, biochemistry, and behavior 1989;32(1):111-5.
1989: N Zarković; Hari Manev; D Pericić; K Skala; M Jurin; A Persin; M Kubović
Effect of semiconductor GaAs laser irradiation on pain perception in mice.
Lasers in surgery and medicine 1989;9(1):63-6.
1988: M Favaron; Hari Manev; Hannu Alho; M Bertolino; B Ferret; Alessandro Guidotti; Erminio Costa
Gangliosides prevent glutamate and kainate neurotoxicity in primary neuronal cultures of neonatal rat cerebellum and cortex.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7351-5.
1988: D Pericić; Hari Manev
Behavioural evidence for simultaneous dual changes of 5-HT receptor subtypes: mode of antidepressant action?
Life sciences 1988;42(25):2593-601.
1988: Hari Manev; Danka Pericic
Effects of the potential antidepressant dihydroergosine in rats forced to swim: influence on plasma corticosterone.
Psychoneuroendocrinology 1988;13(6):465-9.
1987: Hari Manev; D Pericić
Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats.
Pharmacology, biochemistry, and behavior 1987;28(4):443-6.
1987: D Pericić; Hari Manev
Serotoninergic neurons: long-lasting activation by a possible antidepressant dihydroergosine.
European journal of pharmacology 1987;137(1):123-5.
1987: Hari Manev; D Pericić
Sex difference in the turnover of GABA in the rat substantia nigra.
Journal of neural transmission 1987;70(3-4):321-8.
1987: D Pericić; Hari Manev; M Boranić; M Poljak-Blazi; N Lakić
Effect of diazepam on brain neurotransmitters, plasma corticosterone, and the immune system of stressed rats.
Annals of the New York Academy of Sciences 1987;496():450-8.
1987: Hari Manev; D Pericić; S Anić-Stojiljković
Sex differences in the sensitivity of CBA mice to convulsions induced by GABA antagonists are age-dependent.
Psychopharmacology 1987;91(2):226-9.
1986: D Pericić; Hari Manev; J Geber
Sex related differences in the response of mice, rats and cats to administration of picrotoxin.
Life sciences 1986;38(10):905-13.
1986: N Lakić; D Pericić; Hari Manev
Mechanisms by which picrotoxin and a high dose of diazepam elevate plasma corticosterone level.
Neuroendocrinology 1986;43(3):331-5.
1986: D Pericić; Hari Manev; S Levanat; B Jernej; D Vujić; N Djordjević
Effect of dihydroergosine (DHESN) on the serotoninergic system and behaviour: is DHESN a new antidepressive agent?
Psychopharmacology 1986;90(1):112-8.
1985: Hari Manev; D Pericić
Hypophysial GABA after ether stress, dexamethasone or inhibition of GABA catabolism.
Pharmacology, biochemistry, and behavior 1985;23(5):697-700.
1985: D Pericić; Hari Manev; N Lakić
Sex differences in the response of rats to drugs affecting GABAergic transmission.
Life sciences 1985;36(6):541-7.
1984: D Pericić; N Lakić; Hari Manev
Effect of diazepam on plasma corticosterone levels.
Psychopharmacology 1984;83(1):79-81.
1983: Hari Manev; D Pericić
Hypothalamic GABA system and plasma corticosterone in ether stressed rats.
Pharmacology, biochemistry, and behavior 1983;18(6):847-50.
1983: D Pericić; Hari Manev
Effect of phenoxybenzamine on the GABA system and on convulsive activity.
Neuropsychobiology 1983;10(1):23-8.
1983: D Pericić; Hari Manev
Effect of dihydroergotoxine on the susceptibility of rats to convulsions produced by different convulsant agents.
Psychopharmacology 1983;80(2):171-3.
1982: Danka Pericic; Hari Manev; Milivoj Boranic; M Poljak-Blazi
Brain monoamines and plasma corticosterone in stressed rats treated with dextroamphetamine or propranolol.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1982;36(6-7):291-6.
1982: Milivoj Boranic; M Poljak-Blazi; Danka Pericic; Hari Manev
Immune response of stressed rats treated with dextro-amphetamine or propranolol.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1982;36(4):203-5.