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Lara Mangravite

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Robert M Plenge; Eli A Stahl; Anne Barton; S Louis Bridges; Marieke J H Coenen; Niek de Vries; Jonathan M J Derry; Stephen H Friend; Jeffrey D Greenberg; Peter K Gregersen; Henk-Jan Guchelaar; Tom W J Huizinga; Lars Klareskog; Lara M Mangravite; Xavier Mariette; Larry W Moreland; Leonid Padyukov; Gustavo Stolovitzky
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
Adam A Margolin; Brigham H Mecham; Thea C Norman; Lars Ottestad; Daehoon Park; Tyler Pirtle; Oscar M Rueda; Hege G Russnes; Ben Sauerwine; Xavier Schildwachter; Gustavo Stolovitzky; Veronica O Vang; Hans Kristian Moen Vollan; Lamia Youseff; Carlos Caldas; Craig Citro; Christina Curtis; Nicole A Deflaux; Stephen H Friend; Matthew D Furia; Justin Guinney; Joseph Hellerstein; Bruce Hoff; Erich Huang; Michael R Kellen; Vessela N Kristensen; Lara M Mangravite; Samuel Aparicio; Erhan Bilal; Anne-Lise Børresen-Dale
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.
Chad C Brown; Tammy M Havener; Ronald M Krauss; Lara M Mangravite; Howard L McLeod; Marisa W Medina; Todd Auman; Alison A Motsinger-Reif
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.

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All Publications

2013: Robert M Plenge; Eli A Stahl; Anne Barton; S Louis Bridges; Marieke J H Coenen; Niek de Vries; Jonathan M J Derry; Stephen H Friend; Jeffrey D Greenberg; Peter K Gregersen; Henk-Jan Guchelaar; Tom W J Huizinga; Lars Klareskog; Lara M Mangravite; Xavier Mariette; Larry W Moreland; Leonid Padyukov; Gustavo Stolovitzky
Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
Nature genetics 2013;45(5):468-9.
2013: Adam A Margolin; Brigham H Mecham; Thea C Norman; Lars Ottestad; Daehoon Park; Tyler Pirtle; Oscar M Rueda; Hege G Russnes; Ben Sauerwine; Xavier Schildwachter; Gustavo Stolovitzky; Veronica O Vang; Hans Kristian Moen Vollan; Lamia Youseff; Carlos Caldas; Craig Citro; Christina Curtis; Nicole A Deflaux; Stephen H Friend; Matthew D Furia; Justin Guinney; Joseph Hellerstein; Bruce Hoff; Erich Huang; Michael R Kellen; Vessela N Kristensen; Lara M Mangravite; Samuel Aparicio; Erhan Bilal; Anne-Lise Børresen-Dale
Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer.
Science translational medicine 2013;5(181):181re1.
2012: Chad C Brown; Tammy M Havener; Ronald M Krauss; Lara M Mangravite; Howard L McLeod; Marisa W Medina; Todd Auman; Alison A Motsinger-Reif
A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT.
Pharmacogenetics and genomics 2012;22(11):796-802.
2012: Nastaran Faghihnia; N Bergeron; S Chiu; Lara M Mangravite; Ronald M Krauss
Effects of dietary saturated fat on LDL subclasses and apolipoprotein CIII in men.
European journal of clinical nutrition 2012;66(11):1229-33.
2012: Jonathan M J Derry; Brian Bot; Matthew D Furia; David Henderson; Jonathan Izant; Michael R Kellen; Lara M Mangravite; Xavier Schildwachter; Solveig K Sieberts; Christine Suver; Stephen H Friend
Developing predictive molecular maps of human disease through community-based modeling.
Nature genetics 2012;44(2):127-30.
2012: Marisa W Medina; Devesh Naidoo; Kristen Stevens; Elizabeth Theusch; Frederick Bauzon; Yu-Lin Kuang; Lara M Mangravite; Ronald M Krauss
RHOA is a modulator of the cholesterol-lowering effects of statin.
PLoS genetics 2012;8(11):e1003058.
2011: Lara M Mangravite; Robin S Rawlings; Kathleen Wojnoonski; Nathalie Bergeron; Sally Chiu; Ronald M Krauss
Changes in atherogenic dyslipidemia induced by carbohydrate restriction in men are dependent on dietary protein source.
The Journal of nutrition 2011;141(12):2180-5.
2010: Lara M Mangravite; Marisa Wong Medina; Jinrui Cui; Sheila Pressman; Joshua D Smith; Mark J Rieder; Xiuqing Guo; Deborah A Nickerson; Jerome I Rotter; Ronald M Krauss
Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1485-92.
2010: Mathew J Barber; Lara M Mangravite; Craig L Hyde; Daniel I Chasman; Joshua D Smith; Catherine A McCarty; Xiaohui Li; Russell A Wilke; Mark J Rieder; Paul T Williams; Paul M Ridker; Aurobindo Chatterjee; Jerome I Rotter; Deborah A Nickerson; Matthew Stephens; Ronald M Krauss
Genome-wide association of lipid-lowering response to statins in combined study populations.
PloS one 2010;5(3):e9763.
2009: Marleen Welsh; Lara M Mangravite; Marisa Wong Medina; Kelan Tantisira; Wei Zhang; R Stephanie Huang; howard mcleod; M Eileen Dolan
Pharmacogenomic discovery using cell-based models.
Pharmacological reviews 2009;61(4):413-29.
2008: Maxwell A Ruby; Daniel Nomura; Carolyn S S Hudak; Lara M Mangravite; Sally Chiu; John E Casida; Ronald M Krauss
Overactive endocannabinoid signaling impairs apolipoprotein E-mediated clearance of triglyceride-rich lipoproteins.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14561-6.
2008: Ronald M Krauss; Lara M Mangravite; Joshua D Smith; Marisa W Medina; Dai Wang; Xiuqing Guo; Mark J Rieder; Joel A Simon; Steven B Hulley; David Waters; Mohammed Saad; Paul T Williams; Kent D Taylor; Huiying Yang; Deborah A Nickerson; Jerome I Rotter
Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment.
Circulation 2008;117(12):1537-44.
2007: Lara M Mangravite; Kevin Dawson; Ryan R Davis; Jeffrey P Gregg; Ronald M Krauss
Fatty acid desaturase regulation in adipose tissue by dietary composition is independent of weight loss and is correlated with the plasma triacylglycerol response.
The American journal of clinical nutrition 2007;86(3):759-67.
2007: Lara M Mangravite; Ronald M Krauss
Pharmacogenomics of statin response.
Current opinion in lipidology 2007;18(4):409-14.
2006: Andrew R Erdman; Lara M Mangravite; Thomas J Urban; Leah L Lagpacan; Richard A Castro; Melanie de la Cruz; Wendy Chan; Conrad C Huang; Susan J Johns; Michiko Kawamoto; Doug Stryke; Travis R Taylor; Elaine J Carlson; Thomas E Ferrin; Claire M Brett; Esteban González Burchard; Kathleen M Giacomini
The human organic anion transporter 3 (OAT3; SLC22A8): genetic variation and functional genomics.
American journal of physiology. Renal physiology 2006;290(4):F905-12.
2004: Yan Shu; Maya K Leabman; Bo Feng; Lara M Mangravite; Conrad C Huang; Doug Stryke; Michiko Kawamoto; Susan J Johns; Joseph DeYoung; Elaine Carlson; Thomas E Ferrin; Ira Herskowitz; Kathleen M Giacomini
PharmGKB update: III. Genetic variants of SLC22A1, solute carrier family 22 (organic cation transporter), member 1.
Pharmacological reviews 2004;56(2):161.
2004: Jennifer H Gray; Lara M Mangravite; Ryan P Owen; Thomas J Urban; Wendy Chan; Elaine J Carlson; Conrad C Huang; Michiko Kawamoto; Susan J Johns; Doug Stryke; Thomas E Ferrin; Kathleen M Giacomini
Functional and genetic diversity in the concentrative nucleoside transporter, CNT1, in human populations.
Molecular pharmacology 2004;65(3):512-9.
2003: Lara M Mangravite; Ilaria Badagnani; Kathleen M Giacomini
Nucleoside transporters in the disposition and targeting of nucleoside analogs in the kidney.
European journal of pharmacology 2003;479(1-3):269-81.
2003: Yan Shu; Maya K Leabman; Bo Feng; Lara M Mangravite; Conrad C Huang; Doug Stryke; Michiko Kawamoto; Susan J Johns; Joseph DeYoung; Elaine Carlson; Thomas E Ferrin; Ira Herskowitz; Kathleen M Giacomini
Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5902-7.
2003: Lara M Mangravite; Guangqing Xiao; Kathleen M Giacomini
Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells.
American journal of physiology. Renal physiology 2003;284(5):F902-10.
2003: Lara M Mangravite; Kathleen M Giacomini
Sorting of rat SPNT in renal epithelium is independent of N-glycosylation.
Pharmaceutical research 2003;20(2):319-23.
2001: Yan Shu; C L Bello; Lara M Mangravite; B Feng; Kathleen M Giacomini
Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells.
The Journal of pharmacology and experimental therapeutics 2001;299(1):392-8.
2001: Carolyn L Cummins; Lara M Mangravite; Leslie Z Benet
Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Pharmaceutical research 2001;18(8):1102-9.
2001: Lara M Mangravite; Joshua H Lipschutz; Keith E Mostov; Kathleen M Giacomini
Localization of GFP-tagged concentrative nucleoside transporters in a renal polarized epithelial cell line.
American journal of physiology. Renal physiology 2001;280(5):F879-85.