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Charlotte Manisty

Research Profile

Disorders

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Artificial Cardiac Pacing

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Publications

TOP 3
Justin E Davies; Anthony J Barron; Mohamad Hamady; Alun D Hughes; Charlotte H Manisty; Jamil Mayet; Ricardo Petraco; Peter S Sever; Paul A Sobotka; Beth Unsworth; Darrel P Francis
First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study.
Charlotte H Manisty; Alun D Hughes
Meta-analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index.
Justin E Davies; Rodney A Foale; Darrel P Francis; Nearchos Hadjiloizou; Alun D Hughes; Iqbal S Malik; Charlotte H Manisty; Jazmin Aguado-Sierra; Jordi Alastruey; Kim H Parker; Zachary I Whinnett; Keith Willson; Jamil Mayet
Attenuation of wave reflection by wave entrapment creates a "horizon effect" in the human aorta.

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All Publications

2013: Justin E Davies; Anthony J Barron; Mohamad Hamady; Alun D Hughes; Charlotte H Manisty; Jamil Mayet; Ricardo Petraco; Peter S Sever; Paul A Sobotka; Beth Unsworth; Darrel P Francis
First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study.
International journal of cardiology 2013;162(3):189-92.
2013: Charlotte H Manisty; Alun D Hughes
Meta-analysis of the comparative effects of different classes of antihypertensive agents on brachial and central systolic blood pressure, and augmentation index.
British journal of clinical pharmacology 2013;75(1):79-92.
2012: Justin E Davies; Rodney A Foale; Darrel P Francis; Nearchos Hadjiloizou; Alun D Hughes; Iqbal S Malik; Charlotte H Manisty; Jazmin Aguado-Sierra; Jordi Alastruey; Kim H Parker; Zachary I Whinnett; Keith Willson; Jamil Mayet
Attenuation of wave reflection by wave entrapment creates a "horizon effect" in the human aorta.
Hypertension 2012;60(3):778-85.
2012: Charlotte H Manisty; Jamil Mayet; Punam A Pabari; Beth Unsworth; Zachary I Whinnett; Ali Al-Hussaini; Resham Baruah; Alun HUGHES; Darrel P Francis
The acute effects of changes to AV delay on BP and stroke volume: potential implications for design of pacemaker optimization protocols.
Circulation. Arrhythmia and electrophysiology 2012;5(1):122-30.
2011: Zachary I Whinnett; Gemma Nott; Justin E R Davies; Keith Willson; Charlotte H Manisty; Prapa Kanagaratnam; Nicholas S Peters; D Wyn Davies; Alun D Hughes; Jamil Mayet; Darrel P Francis
Maximizing efficiency of alternation algorithms for hemodynamic optimization of the AV delay of cardiac resynchronization therapy.
Pacing and clinical electrophysiology : PACE 2011;34(2):217-25.
2010: Alberto Giannoni; Resham Baruah; Keith Willson; Yoseph Mebrate; Jamil Mayet; Michele Emdin; Alun D Hughes; Charlotte H Manisty; Darrel P Francis
Real-time dynamic carbon dioxide administration: a novel treatment strategy for stabilization of periodic breathing with potential application to central sleep apnea.
Journal of the American College of Cardiology 2010;56(22):1832-7.
2010: Charlotte H Manisty; Jamil Mayet; Robyn J Tapp; Kim H Parker; Peter S Sever; Neil R Poulter; Neil H Poulter; Simon A McG Thom; Alun HUGHES
Wave reflection predicts cardiovascular events in hypertensive individuals independent of blood pressure and other cardiovascular risk factors: an ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) substudy.
Journal of the American College of Cardiology 2010;56(1):24-30.
2010: Justin E Davies; John Baksi; Darrel P Francis; Nearchos Hadjiloizou; Zachary I Whinnett; Charlotte H Manisty; Jazmin Aguado-Sierra; Rodney A Foale; Iqbal S Malik; John V Tyberg; Kim H Parker; Jamil Mayet; Alun D Hughes
The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index.
American journal of physiology. Heart and circulatory physiology 2010;298(2):H580-6.
2009: Charlotte H Manisty; Jamil Mayet; Robyn J Tapp; Peter S Sever; Neil Poulter; Simon A McG Thom; Alun HUGHES
Atorvastatin treatment is associated with less augmentation of the carotid pressure waveform in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcome Trial (ASCOT).
Hypertension 2009;54(5):1009-13.
2009: Charlotte H Manisty; Andrew Zambanini; Kim H Parker; Justin E Davies; Darrel P Francis; Jamil Mayet; Simon A McG Thom; Alun HUGHES
Differences in the magnitude of wave reflection account for differential effects of amlodipine- versus atenolol-based regimens on central blood pressure: an Anglo-Scandinavian Cardiac Outcome Trial substudy.
Hypertension 2009;54(4):724-30.
2009: Yoseph Mebrate; Keith Willson; Charlotte H Manisty; Resham Baruah; Jamil Mayet; Alun D Hughes; Kim H Parker; Darrel P Francis
Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;107(3):696-706.
2009: Resham Baruah; Charlotte H Manisty; Alberto Giannoni; Keith Willson; Yoseph Mebrate; A John Baksi; Beth Unsworth; Nearchos Hadjiloizou; Richard Sutton; Jamil Mayet; Darrel P Francis
Novel use of cardiac pacemakers in heart failure to dynamically manipulate the respiratory system through algorithmic changes in cardiac output.
Circulation. Heart failure 2009;2(3):166-74.
2009: C E Raphael; Zachary I Whinnett; Justin E Davies; M Fontana; E A Ferenczi; Charlotte H Manisty; Jamil Mayet; Darrel P Francis
Quantifying the paradoxical effect of higher systolic blood pressure on mortality in chronic heart failure.
Heart (British Cardiac Society) 2009;95(1):56-62.
2008: Zachary I Whinnett; Justin E R Davies; Gemma Nott; Keith Willson; Charlotte H Manisty; Nicholas S Peters; Prapa Kanagaratnam; D Wyn Davies; Alun HUGHES; Jamil Mayet; Darrel P Francis
Efficiency, reproducibility and agreement of five different hemodynamic measures for optimization of cardiac resynchronization therapy.
International journal of cardiology 2008;129(2):216-26.
2008: Charlotte H Manisty; Keith Willson; Justin E R Davies; Zachary I Whinnett; Resham Baruah; Yoseph Mebrate; Prapa Kanagaratnam; Nicholas S Peters; Alun HUGHES; Jamil Mayet; Darrel P Francis
Induction of oscillatory ventilation pattern using dynamic modulation of heart rate through a pacemaker.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(1):R219-27.
2008: Charlotte H Manisty; Darrel P Francis
Ejection fraction: a measure of desperation?
Heart (British Cardiac Society) 2008;94(4):400-1.
2008: Zachary I Whinnett; Cathy Briscoe; Justin E R Davies; Keith Willson; Charlotte H Manisty; D Wyn Davies; Nicholas S Peters; Prapa Kanagaratnam; Alun HUGHES; Jamil Mayet; Darrel P Francis
The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements.
Heart rhythm : the official journal of the Heart Rhythm Society 2008;5(3):378-86.
2007: Claire Raphael; Cathy Briscoe; Justin Davies; Zachary Ian Whinnett; Charlotte H Manisty; Richard Sutton; Jamil Mayet; Darrel P Francis
Limitations of the New York Heart Association functional classification system and self-reported walking distances in chronic heart failure.
Heart (British Cardiac Society) 2007;93(4):476-82.
2007: Charlotte H Manisty; Darrel P Francis
Increased mechanoreceptor/metaboreceptor stimulation explains the exaggerated exercise pressor reflex seen in heart failure.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(1):501; author reply 504-5.
2006: Charlotte H Manisty; Keith Willson; Roland Wensel; Zachary I Whinnett; Justin E Davies; William L G Oldfield; Jamil Mayet; Darrel P Francis
Development of respiratory control instability in heart failure: a novel approach to dissect the pathophysiological mechanisms.
The Journal of physiology 2006;577(Pt 1):387-401.
2006: Zachary I Whinnett; J E R Davies; Keith Willson; Charlotte H Manisty; Anthony W C Chow; Rodney A Foale; D Wyn Davies; Alun HUGHES; Jamil Mayet; Darrel P Francis
Haemodynamic effects of changes in atrioventricular and interventricular delay in cardiac resynchronisation therapy show a consistent pattern: analysis of shape, magnitude and relative importance of atrioventricular and interventricular delay.
Heart (British Cardiac Society) 2006;92(11):1628-34.
2006: Justin E Davies; Zachary I Whinnett; Darrel P Francis; Charlotte H Manisty; Jazmin Aguado-Sierra; Keith Willson; Rodney A Foale; Iqbal S Malik; Alun HUGHES; Kim H Parker; Jamil Mayet
Evidence of a dominant backward-propagating "suction" wave responsible for diastolic coronary filling in humans, attenuated in left ventricular hypertrophy.
Circulation 2006;113(14):1768-78.
2003: Charlotte H Manisty; Jonathan Waxman
Doctors should not discuss resuscitation with terminally ill patients: FOR.
BMJ (Clinical research ed.) 2003;327(7415):614-5.