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D M A Mann

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

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Foulds Penelope; McAuley Erica; Gibbons Linda; Davidson Yvonne; Pickering-Brown Stuart M; Neary David; Snowden Julie S; Allsop David; Mann David M A
TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.
Belbin O; Dunn J L; Chappell S; Ritchie A E; Ling Y; Morgan L; Pritchard A; Warden D R; Lendon C L; Lehmann D J; Mann D M A; Smith A D; Kalsheker N; Morgan K
A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.
Dreses-Werringloer Ute; Lambert Jean-Charles; Vingtdeux Valérie; Zhao Haitian; Vais Horia; Siebert Adam; Jain Ankit; Koppel Jeremy; Rovelet-Lecrux Anne; Hannequin Didier; Pasquier Florence; Galimberti Daniela; Scarpini Elio; Mann David; Lendon Corinne; Campion Dominique; Amouyel Philippe; Davies Peter; Foskett J Kevin; Campagne Fabien; Marambaud Philippe
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.

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All Publications

2008: Foulds Penelope; McAuley Erica; Gibbons Linda; Davidson Yvonne; Pickering-Brown Stuart M; Neary David; Snowden Julie S; Allsop David; Mann David M A
TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.
Acta neuropathologica 2008;116(2):141-6.
2008: Belbin O; Dunn J L; Chappell S; Ritchie A E; Ling Y; Morgan L; Pritchard A; Warden D R; Lendon C L; Lehmann D J; Mann D M A; Smith A D; Kalsheker N; Morgan K
A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.
Neurobiology of aging 2008;29(8):1167-76.
2008: Dreses-Werringloer Ute; Lambert Jean-Charles; Vingtdeux Valérie; Zhao Haitian; Vais Horia; Siebert Adam; Jain Ankit; Koppel Jeremy; Rovelet-Lecrux Anne; Hannequin Didier; Pasquier Florence; Galimberti Daniela; Scarpini Elio; Mann David; Lendon Corinne; Campion Dominique; Amouyel Philippe; Davies Peter; Foskett J Kevin; Campagne Fabien; Marambaud Philippe
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk.
Cell 2008;133(7):1149-61.
2008: Chapuis Julien; Hannequin Didier; Pasquier Florence; Bentham Peter; Brice Alexis; Leber Isabelle; Frebourg Thierry; Deleuze Jean-François; Cousin Emmanuelle; Thaker Uma; Amouyel Philippe; Mann David; Lendon Corinne; Campion Dominique; Lambert Jean-Charles
Association study of the GAB2 gene with the risk of developing Alzheimer's disease.
Neurobiology of disease 2008;30(1):103-6.
2008: Pickering-Brown Stuart M; Rollinson Sara; Du Plessis Daniel; Morrison Karen E; Varma Anoop; Richardson Anna M T; Neary David; Snowden Julie S; Mann David M A
Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations.
Brain : a journal of neurology 2008;131(Pt 3):721-31.
2008: Bowen D M; Procter A W; Mann D M A; Snowden J S; Esiri M M; Neary D; Francis P T
Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy.
Psychopharmacology 2008;196(4):603-10.
2007: Snowden Julie S; Pickering-Brown Stuart M; Du Plessis Daniel; Mackenzie Ian R A; Varma Anoop; Mann David M A; Neary David
Progressive anomia revisited: focal degeneration associated with progranulin gene mutation.
Neurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology 2007;13(5):366-77.
2007: Snowden Julie S; Stopford Cheryl L; Julien Camille L; Thompson Jennifer C; Davidson Yvonne; Gibbons Linda; Pritchard Antonia; Lendon Corinne L; Richardson Anna M; Varma Anoop; Neary David; Mann David
Cognitive phenotypes in Alzheimer's disease and genetic risk.
Cortex; a journal devoted to the study of the nervous system and behavior 2007;43(7):835-45.
2007: Doran Mark; du Plessis Daniel G; Ghadiali Eric J; Mann David M A; Pickering-Brown Stuart; Larner Andrew J
Familial early-onset dementia with tau intron 10 + 16 mutation with clinical features similar to those of Alzheimer disease.
Archives of neurology 2007;64(10):1535-9.
2007: Ishii Aasami; Nonaka Takashi; Taniguchi Sayuri; Saito Taro; Arai Tetsuaki; Mann David; Iwatsubo Takeshi; Hisanaga Shin-Ichi; Goedert Michel; Hasegawa Masato
Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.
FEBS letters 2007;581(24):4711-7.
2007: Rademakers Rosa; Baker Matt; Gass Jennifer; Adamson Jennifer; Huey Edward D; Momeni Parastoo; Spina Salvatore; Coppola Giovanni; Karydas Anna M; Stewart Heather; Johnson Nancy; Hsiung Ging-Yuek; Kelley Brendan; Kuntz Karen; Steinbart Ellen; Wood Elisabeth McCarty; Yu Chang-En; Josephs Keith; Sorenson Eric; Womack Kyle B; Weintraub Sandra; Pickering-Brown Stuart M; Schofield Peter R; Brooks William S; Van Deerlin Vivianna M; Snowden Julie; Clark Christopher M; Kertesz Andrew; Boylan Kevin; Ghetti Bernardino; Neary David; Schellenberg Gerard D; Beach Thomas G; Mesulam Marsel; Mann David; Grafman Jordan; Mackenzie Ian R; Feldman Howard; Bird Thomas; Petersen Ron; Knopman David; Boeve Bradley; Geschwind Dan H; Miller Bruce; Wszolek Zbigniew; Lippa Carol; Bigio Eileen H; Dickson Dennis; Graff-Radford Neill; Hutton Mike
Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative.
Lancet neurology 2007;6(10):857-68.
2007: Kumaran Ravindran; Kingsbury Ann; Coulter Ian; Lashley Tammaryn; Williams David; de Silva Rohan; Mann David; Revesz Tamas; Lees Andrew; Bandopadhyay Rina
DJ-1 (PARK7) is associated with 3R and 4R tau neuronal and glial inclusions in neurodegenerative disorders.
Neurobiology of disease 2007;28(1):122-32.
2007: Salem Sultan A; Allsop David; Mann David M A; Tokuda Takahiko; El-Agnaf Omar M A
An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid.
Brain research 2007;1170():103-11.
2007: Lambert J-C; Ferreira S; Gussekloo J; Christiansen L; Brysbaert G; Slagboom E; Cottel D; Petit T; Hauw J-J; DeKosky S T; Richard F; Berr C; Lendon C; Kamboh M Ilyas; Mann D; Christensen K; Westendorp R; Amouyel P
Evidence for the association of the S100beta gene with low cognitive performance and dementia in the elderly.
Molecular psychiatry 2007;12(9):870-80.
2007: Cairns Nigel J; Bigio Eileen H; Mackenzie Ian R A; Neumann Manuela; Lee Virginia M-Y; Hatanpaa Kimmo J; White Charles L; Schneider Julie A; Grinberg Lea Tenenholz; Halliday Glenda; Duyckaerts Charles; Lowe James S; Holm Ida E; Tolnay Markus; Okamoto Koichi; Yokoo Hideaki; Murayama Shigeo; Woulfe John; Munoz David G; Dickson Dennis W; Ince Paul G; Trojanowski John Q; Mann David M A;
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Acta neuropathologica 2007;114(1):5-22.
2007: Mann David
Frontotemporal lobar degeneration--a coming of age.
Acta neuropathologica 2007;114(1):1-4.
2007: Snowden Julie; Neary David; Mann David
Frontotemporal lobar degeneration: clinical and pathological relationships.
Acta neuropathologica 2007;114(1):31-8.
2007: Shepherd C E; Grace E M; Mann D M A; Halliday G M
Relationship between neuronal loss and 'inflammatory plaques' in early onset Alzheimer's disease.
Neuropathology and applied neurobiology 2007;33(3):328-33.
2007: Rollinson Sara; Snowden Julie S; Neary David; Morrison Karen E; Mann David M A; Pickering-Brown Stuart M
TDP-43 gene analysis in frontotemporal lobar degeneration.
Neuroscience letters 2007;419(1):1-4.
2007: Davidson Yvonne; Kelley Thomas; Mackenzie Ian R A; Pickering-Brown Stuart; Du Plessis Daniel; Neary David; Snowden Julie S; Mann David M A
Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43.
Acta neuropathologica 2007;113(5):521-33.
2007: McNeill R; Sare G M; Manoharan M; Testa H J; Mann D M A; Neary D; Snowden J S; Varma A R
Accuracy of single-photon emission computed tomography in differentiating frontotemporal dementia from Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2007;78(4):350-5.
2007: Boddaert Jacques; Kinugawa Kiyoka; Lambert Jean-Charles; Boukhtouche Fatiha; Zoll Joffrey; Merval Régine; Blanc-Brude Olivier; Mann David; Berr Claudine; Vilar José; Garabedian Béatrice; Journiac Nathalie; Charue Dominique; Silvestre Jean-Sébastien; Duyckaerts Charles; Amouyel Philippe; Mariani Jean; Tedgui Alain; Mallat Ziad
Evidence of a role for lactadherin in Alzheimer's disease.
The American journal of pathology 2007;170(3):921-9.
2007: Davidson Yvonne; Gibbons Linda; Pritchard Antonia; Hardicre Jayne; Wren Joanne; Stopford Cheryl; Julien Camille; Thompson Jennifer; Payton Antony; Pickering-Brown Stuart M; Pendleton Neil; Horan Michael A; Burns Alistair; Purandare Nitin; Lendon Corinne L; Neary David; Snowden Julie S; Mann David M A
Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease.
Dementia and geriatric cognitive disorders 2007;23(1):60-6.
2006: Momeni Parastoo; Bell Jason; Duckworth Jaime; Hutton Mike; Mann David; Brown Stuart Pickering; Hardy John
Sequence analysis of all identified open reading frames on the frontal temporal dementia haplotype on chromosome 3 fails to identify unique coding variants except in CHMP2B.
Neuroscience letters 2006;410(2):77-9.
2006: Arai Tetsuaki; Hasegawa Masato; Akiyama Haruhiko; Ikeda Kenji; Nonaka Takashi; Mori Hiroshi; Mann David; Tsuchiya Kuniaki; Yoshida Mari; Hashizume Yoshio; Oda Tatsuro
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Biochemical and biophysical research communications 2006;351(3):602-11.
2006: Pickering-Brown Stuart M; Baker Matt; Gass Jenny; Boeve Bradley F; Loy Clement T; Brooks William S; Mackenzie Ian R A; Martins Ralph N; Kwok John B J; Halliday Glenda M; Kril Jillian; Schofield Peter R; Mann David M A; Hutton Mike
Mutations in progranulin explain atypical phenotypes with variants in MAPT.
Brain : a journal of neurology 2006;129(Pt 11):3124-6.
2006: Mackenzie Ian R A; Baborie Atik; Pickering-Brown Stuart; Du Plessis Daniel; Jaros Evelyn; Perry Robert H; Neary David; Snowden Julie S; Mann David M A
Heterogeneity of ubiquitin pathology in frontotemporal lobar degeneration: classification and relation to clinical phenotype.
Acta neuropathologica 2006;112(5):539-49.
2006: Snowden J S; Pickering-Brown S M; Mackenzie I R; Richardson A M T; Varma A; Neary D; Mann D M A
Progranulin gene mutations associated with frontotemporal dementia and progressive non-fluent aphasia.
Brain : a journal of neurology 2006;129(Pt 11):3091-102.
2006: Mackenzie Ian R A; Shi Jing; Shaw Catherine L; Duplessis Daniel; Neary David; Snowden Julie S; Mann David M A
Dementia lacking distinctive histology (DLDH) revisited.
Acta neuropathologica 2006;112(5):551-9.
2006: Purandare Nitin; Oude Voshaar Richard C; Davidson Yvonne; Gibbons Linda; Hardicre Jayne; Byrne Jane; McCollum Charles; Jackson Alan; Burns Alistair; Mann David M A
Deletion/insertion polymorphism of the angiotensin-converting enzyme gene and white matter hyperintensities in dementia: A pilot study.
Journal of the American Geriatrics Society 2006;54(9):1395-400.
2006: Chapuis Julien; Tian Jinzhou; Shi Jing; Bensemain Faiza; Cottel Dominique; Lendon Corinne; Amouyel Philippe; Mann David; Lambert Jean-Charles
Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease.
Neurobiology of aging 2006;27(9):1212-5.
2006: Shiarli A-M; Jennings R; Shi J; Bailey K; Davidson Y; Tian J; Bigio E H; Ghetti B; Murrell J R; Delisle M B; Mirra S; Crain B; Zolo P; Arima K; Iseki E; Murayama S; Kretzschmar H; Neumann M; Lippa C; Halliday G; Mackenzie J; Khan N; Ravid R; Dickson D; Wszolek Z; Iwatsubo T; Pickering-Brown S M; Mann D M A
Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease.
Neuropathology and applied neurobiology 2006;32(4):374-87.
2006: Liu Kangning; Solano Ingrid; Mann David; Lemere Cynthia; Mercken Marc; Trojanowski John Q; Lee Virginia M-Y
Characterization of Abeta11-40/42 peptide deposition in Alzheimer's disease and young Down's syndrome brains: implication of N-terminally truncated Abeta species in the pathogenesis of Alzheimer's disease.
Acta neuropathologica 2006;112(2):163-74.
2006: Baker Matt; Mackenzie Ian R; Pickering-Brown Stuart M; Gass Jennifer; Rademakers Rosa; Lindholm Caroline; Snowden Julie; Adamson Jennifer; Sadovnick A Dessa; Rollinson Sara; Cannon Ashley; Dwosh Emily; Neary David; Melquist Stacey; Richardson Anna; Dickson Dennis; Berger Zdenek; Eriksen Jason; Robinson Todd; Zehr Cynthia; Dickey Chad A; Crook Richard; McGowan Eileen; Mann David; Boeve Bradley; Feldman Howard; Hutton Mike
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.
Nature 2006;442(7105):916-9.
2006: Tian J; Shi J; Smallman R; Iwatsubo T; Mann D M A
Relationships in Alzheimer's disease between the extent of Abeta deposition in cerebral blood vessel walls, as cerebral amyloid angiopathy, and the amount of cerebrovascular smooth muscle cells and collagen.
Neuropathology and applied neurobiology 2006;32(3):332-40.
2006: Bensemain Faiza; Chapuis Julien; Tian Jinzhou; Shi Jing; Thaker Uma; Lendon Corinne; Iwatsubo Takeshi; Amouyel Philippe; Mann David; Lambert Jean-Charles
Association study of the Ubiquilin gene with Alzheimer's disease.
Neurobiology of disease 2006;22(3):691-3.
2006: Cannon Ashley; Baker Matthew; Boeve Brad; Josephs Keith; Knopman David; Petersen Ron; Parisi Joseph; Dickison Dennis; Adamson Jennifer; Snowden Julie; Neary David; Mann David; Hutton Mike; Pickering-Brown Stuart M
CHMP2B mutations are not a common cause of frontotemporal lobar degeneration.
Neuroscience letters 2006;398(1-2):83-4.
2006: de Silva Rohan; Lashley Tammaryn; Strand Catherine; Shiarli Anna-Maria; Shi Jing; Tian Jinzhou; Bailey Kathryn L; Davies Peter; Bigio Eileen H; Arima Kunimasa; Iseki Eizo; Murayama Shigeo; Kretzschmar Hans; Neumann Manuela; Lippa Carol; Halliday Glenda; MacKenzie James; Ravid Rivka; Dickson Dennis; Wszolek Zbigniew; Iwatsubo Takeshi; Pickering-Brown Stuart M; Holton Janice; Lees Andrew; Revesz Tamas; Mann David M A
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies.
Acta neuropathologica 2006;111(4):329-40.
2006: Davidson Y; Gibbons L; Pritchard A; Hardicre J; Wren J; Tian J; Shi J; Stopford C; Julien C; Thompson J; Payton A; Thaker U; Hayes A J; Iwatsubo T; Pickering-Brown S M; Pendleton N; Horan M A; Burns A; Purandare N; Lendon C L; Neary D; Snowden J S; Mann D M A
Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotype.
Journal of neurology, neurosurgery, and psychiatry 2006;77(4):515-7.
2006: Srinivasan R; Davidson Y; Gibbons L; Payton A; Richardson A M T; Varma A; Julien C; Stopford C; Thompson J; Horan M A; Pendleton N; Pickering-Brown S M; Neary D; Snowden J S; Mann D M A
The apolipoprotein E epsilon4 allele selectively increases the risk of frontotemporal lobar degeneration in males.
Journal of neurology, neurosurgery, and psychiatry 2006;77(2):154-8.
2006: van Leeuwen F W; van Tijn P; Sonnemans M A F; Hobo B; Mann D M A; Van Broeckhoven C; Kumar-Singh S; Cras P; Leuba G; Savioz A; Maat-Schieman M L C; Yamaguchi H; Kros J M; Kamphorst W; Hol E M; de Vos R A I; Fischer D F
Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies.
Neurology 2006;66(2 Suppl 1):S86-92.
2006: Shi Jing; Tian Jinzhou; Pritchard Antonia; Lendon Corinne; Lambert Jean-Charles; Iwatsubo Takeshi; Mann David M A
A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease.
Acta neuropathologica 2006;111(1):15-20.
2006: Davidson Yvonne; Gibbons Linda; Purandare Nitin; Byrne Jane; Hardicre Jayne; Wren Joanne; Payton Antony; Pendleton Neil; Horan Michael; Burns Alistair; Mann David M A
Apolipoprotein E epsilon4 allele frequency in vascular dementia.
Dementia and geriatric cognitive disorders 2006;22(1):15-9.
2005: Neary David; Snowden Julie; Mann David
Frontotemporal dementia.
Lancet neurology 2005;4(11):771-80.
2005: Shi Jing; Shaw Catherine L; Du Plessis Daniel; Richardson Anna M T; Bailey Kathryn L; Julien Camille; Stopford Cheryl; Thompson Jennifer; Varma Anoop; Craufurd David; Tian Jinzhou; Pickering-Brown Stuart; Neary David; Snowden Julie S; Mann David M A
Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation.
Acta neuropathologica 2005;110(5):501-12.
2005: Miyasaka Tomohiro; Watanabe Atsushi; Saito Yuko; Murayama Shigeo; Mann David M A; Yamazaki Mineo; Ravid Rivka; Morishima-Kawashima Maho; Nagashima Kazuo; Ihara Yasuo
Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads.
Journal of neuropathology and experimental neurology 2005;64(8):665-74.
2005: Lambert J-C; Mann D; Richard F; Tian J; Shi J; Thaker U; Merrot S; Harris J; Frigard B; Iwatsubo T; Lendon C; Amouyel P
Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?
Journal of neurology, neurosurgery, and psychiatry 2005;76(7):928-33.
2005: Pritchard Antonia; Harris Judith; Pritchard Colin W; St Clair David; Lemmon Helen; Lambert Jean-Charles; Chartier-Harlin Marie-Christine; Hayes Angela; Thaker Uma; Iwatsubo Takeshi; Mann David M A; Lendon Corinne
Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease.
Neuroscience letters 2005;382(3):221-6.
2005: Broe Melissa; Shepherd Claire E; Mann David M A; Milward Elizabeth A; Gai Wei-Ping; Thiel Emma; Halliday Glenda M
Insoluble alpha-synuclein in Alzheimer's disease without Lewy body formation.
Neurotoxicity research 2005;7(1-2):69-76.
2004: Tian J; Shi J; Mann D M A
Cerebral amyloid angiopathy and dementia.
Panminerva medica 2004;46(4):253-64.
2004: Hayes A; Green E K; Pritchard A; Harris J M; Zhang Y; Lambert J C; Chartier-Harlin M C; Pickering-Brown S M; Lendon C L; Mann D M A
A polymorphic variation in the interleukin 1A gene increases brain microglial cell activity in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2004;75(10):1475-7.
2004: Snowden J S; Neary D; Mann D M A
Autopsy proven sporadic frontotemporal dementia due to microvacuolar-type histology, with onset at 21 years of age.
Journal of neurology, neurosurgery, and psychiatry 2004;75(9):1337-9.
2004: Pritchard Antonia; St Clair David; Lemmon Helen; Mann David M A; Lendon Corinne
No association between polymorphisms in the lectin-like oxidised low density lipoprotein receptor (ORL1) gene on chromosome 12 and Alzheimer's disease in a UK cohort.
Neuroscience letters 2004;366(2):126-9.
2004: van Dijk R; Fischer D F; Sluijs J A; Sonnemans M A F; Hobo B; Mercken L; Mann D M A; Hol E M; van Leeuwen F W
Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.
Journal of neurochemistry 2004;90(3):712-23.
2004: Kowa Hisatomo; Sakakura Tomoko; Matsuura Yusuke; Wakabayashi Tomoko; Mann David M A; Duff Karen; Tsuji Shoji; Hashimoto Tadafumi; Iwatsubo Takeshi
Mostly separate distributions of CLAC- versus Abeta40- or thioflavin S-reactivities in senile plaques reveal two distinct subpopulations of beta-amyloid deposits.
The American journal of pathology 2004;165(1):273-81.
2004: Pickering-Brown S M; Baker M; Nonaka T; Ikeda K; Sharma S; Mackenzie J; Simpson S A; Moore J W; Snowden J S; de Silva R; Revesz T; Hasegawa M; Hutton M; Mann D M A
Frontotemporal dementia with Pick-type histology associated with Q336R mutation in the tau gene.
Brain : a journal of neurology 2004;127(Pt 6):1415-26.
2004: Zhang Yong; Hayes Angela; Pritchard Antonia; Thaker Uma; Haque M Sayeed; Lemmon Helen; Harris Judith; Cumming Alistair; Lambert Jean-Charles; Chartier-Harlin Marie-Christine; St Clair David; Iwatsubo Takeshi; Mann David M; Lendon Corinne L
Interleukin-6 promoter polymorphism: risk and pathology of Alzheimer's disease.
Neuroscience letters 2004;362(2):99-102.
2004: Tian J; Shi J; Bailey K; Lendon C L; Pickering-Brown S M; Mann D M A
Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2004;75(5):696-9.
2004: Umeda Yuri; Taniguchi Sayuri; Arima Kunimasa; Piao Yue-Shan; Takahashi Hitoshi; Iwatsubo Takeshi; Mann David; Hasegawa Masato
Alterations in human tau transcripts correlate with those of neurofilament in sporadic tauopathies.
Neuroscience letters 2004;359(3):151-4.
2004: Cook Lynnette J; Ho Luk W; Taylor Alison E; Brayne Carol; Evans John Grimley; Xuereb John; Cairns Nigel J; Pritchard Antonia; Lemmon Helen; Mann David; St Clair David; Turic Dragana; Hollingworth Paul; Moore Pamela J; Jehu Luke; Archer Nicola; Walter Sarah; Foy Catherine; Edmondson Amanda; Powell John; Lovestone Simon; Owen Michael J; Williams Julie; Lendon Corinne; Rubinsztein David C
Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.
Neuroscience letters 2004;358(2):142-6.
2004: Lambert J-C; Mann D; Harris J; Araria-Goumidi L; Chartier-Harlin M-C; Cottel D; Iwatsubo T; Amouyel P; Lendon C
Association study of Notch 4 polymorphisms with Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2004;75(3):377-81.
2004: Pickering-Brown Stuart; Baker Matt; Bird Thomas; Trojanowski John; Lee Virginia; Morris Huw; Rossor Martin; Janssen John C; Neary David; Craufurd David; Richardson Anna; Snowden Julie; Hardy John; Mann David; Hutton Mike
Evidence of a founder effect in families with frontotemporal dementia that harbor the tau +16 splice mutation.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;125B(1):79-82.
2004: Tian J; Shi J; Bailey K; Mann D M A
Relationships between arteriosclerosis, cerebral amyloid angiopathy and myelin loss from cerebral cortical white matter in Alzheimer's disease.
Neuropathology and applied neurobiology 2004;30(1):46-56.
2004: Taniguchi S; McDonagh A M; Pickering-Brown S M; Umeda Y; Iwatsubo T; Hasegawa M; Mann D M A
The neuropathology of frontotemporal lobar degeneration with respect to the cytological and biochemical characteristics of tau protein.
Neuropathology and applied neurobiology 2004;30(1):1-18.
2004: Tian J; Shi J; Bailey K; Harris J M; Pritchard A; Lambert J-C; Chartier-Harlin M-C; Pickering-Brown S M; Lendon C L; Mann D M A
A polymorphism in the angiotensin 1-converting enzyme gene is associated with damage to cerebral cortical white matter in Alzheimer's disease.
Neuroscience letters 2004;354(2):103-6.
2004: Busby Victoria; Goossens Steven; Nowotny Petra; Hamilton Gillian; Smemo Scott; Harold Denise; Turic Dragana; Jehu Luke; Myers Amanda; Womick Meredith; Woo Daniel; Compton Danielle; Doil Lisa M; Tacey Kristina M; Lau Kit F; Al-Saraj Safa; Killick Richard; Pickering-Brown Stuart; Moore Pamela; Hollingworth Paul; Archer Nicola; Foy Catherine; Walter Sarah; Lendon Corrine; Iwatsubo Takeshi; Morris John C; Norton Joanne; Mann David; Janssens Barbara; Hardy John; O'Donovan Michael; Jones Lesley; Williams Julie; Holmans Peter; Owen Michael J; Grupe Andrew; Powell John; van Hengel Jolanda; Goate Alison; Van Roy Frans; Lovestone Simon
Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease.
Neuromolecular medicine 2004;5(2):133-46.
2003: Tian J; Shi J; Bailey K; Mann D M A
Negative association between amyloid plaques and cerebral amyloid angiopathy in Alzheimer's disease.
Neuroscience letters 2003;352(2):137-40.
2003: El-Agnaf Omar M A; Salem Sultan A; Paleologou Katerina E; Cooper Leanne J; Fullwood Nigel J; Gibson Mark J; Curran Martin D; Court Jennifer A; Mann David M A; Ikeda Shu-ichi; Cookson Mark R; Hardy John; Allsop David
Alpha-synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1945-7.
2003: Fraser E; McDonagh A M; Head M; Bishop M; Ironside J W; Mann D M A
Neuronal and astrocytic responses involving the serotonergic system in human spongiform encephalopathies.
Neuropathology and applied neurobiology 2003;29(5):482-95.
2003: McCarron M O; Stewart J; McCarron P; Love S; Vinters H V; Ironside J W; Mann D M A; Graham D I; Nicoll J A R
Association between interleukin-1A polymorphism and cerebral amyloid angiopathy-related hemorrhage.
Stroke; a journal of cerebral circulation 2003;34(10):e193-5.
2003: Lambert J-C; Luedecking-Zimmer E; Merrot S; Hayes A; Thaker U; Desai P; Houzet A; Hermant X; Cottel D; Pritchard A; Iwatsubo T; Pasquier F; Frigard B; Conneally P M; Chartier-Harlin M-C; DeKosky S T; Lendon C; Mann D; Kamboh M I; Amouyel P
Association of 3'-UTR polymorphisms of the oxidised LDL receptor 1 (OLR1) gene with Alzheimer's disease.
Journal of medical genetics 2003;40(6):424-30.
2003: Hughes Alun; Mann David; Pickering-Brown Stuart
Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Experimental neurology 2003;181(1):12-6.
2003: Zhukareva Victoria; Sundarraj Sonali; Mann David; Sjogren Magnus; Blenow Kaj; Clark Christopher M; McKeel Daniel W; Goate Alison; Lippa Carol F; Vonsattel Jean-Paul; Growdon John H; Trojanowski John Q; Lee Virginia M-Y
Selective reduction of soluble tau proteins in sporadic and familial frontotemporal dementias: an international follow-up study.
Acta neuropathologica 2003;105(5):469-76.
2003: Thaker U; McDonagh A M; Iwatsubo T; Lendon C L; Pickering-Brown S M; Mann D M A
Tau load is associated with apolipoprotein E genotype and the amount of amyloid beta protein, Abeta40, in sporadic and familial Alzheimer's disease.
Neuropathology and applied neurobiology 2003;29(1):35-44.
2003: Huckvale C; Richardson A M T; Mann D M A; Pickering-Brown S M
Debrisoquine hydroxylase gene polymorphism (CYP2D6*4) in dementia with Lewy bodies.
Journal of neurology, neurosurgery, and psychiatry 2003;74(1):135-6.
2002: Snowden J S; Mann D M A; Neary D
Distinct neuropsychological characteristics in Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(6):686-94.
2002: Hasegawa Masato; Fujiwara Hideo; Nonaka Takashi; Wakabayashi Koichi; Takahashi Hitoshi; Lee Virginia M-Y; Trojanowski John Q; Mann David; Iwatsubo Takeshi
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions.
The Journal of biological chemistry 2002;277(50):49071-6.
2002: Hayes A; Thaker U; Iwatsubo T; Pickering-Brown S M; Mann D M A
Pathological relationships between microglial cell activity and tau and amyloid beta protein in patients with Alzheimer's disease.
Neuroscience letters 2002;331(3):171-4.
2002: Lendon C L; Thaker U; Harris J M; McDonagh A M; Lambert J-C; Chartier-Harlin M-C; Iwatsubo T; Pickering-Brown S M; Mann D M A
The angiotensin 1-converting enzyme insertion (I)/deletion (D) polymorphism does not influence the extent of amyloid or tau pathology in patients with sporadic Alzheimer's disease.
Neuroscience letters 2002;328(3):314-8.
2002: Lambert J-C; Araria-Goumidi L; Myllykangas L; Ellis C; Wang J C; Bullido M J; Harris J M; Artiga M J; Hernandez D; Kwon J M; Frigard B; Petersen R C; Cumming A M; Pasquier F; Sastre I; Tienari P J; Frank A; Sulkava R; Morris J C; St Clair D; Mann D M; Wavrant-DeVrièze F; Ezquerra-Trabalon M; Amouyel P; Hardy J; Haltia M; Valdivieso F; Goate A M; Pérez-Tur J; Lendon C L; Chartier-Harlin M-C
Contribution of APOE promoter polymorphisms to Alzheimer's disease risk.
Neurology 2002;59(1):59-66.
2002: Araria-Goumidi L; Lambert J C; Mann D M A; Lendon C; Frigard B; Iwatsubo T; Cottel D; Amouyel P; Chartier-Harlin M C
Association study of three polymorphisms of TGF-beta1 gene with Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 2002;73(1):62-4.
2002: Zhukareva Victoria; Mann David; Pickering-Brown Stuart; Uryu Kunihiro; Shuck Theresa; Shah Keyur; Grossman Murray; Miller Bruce L; Hulette Christine M; Feinstein Stuart C; Trojanowski John Q; Lee Virginia M-Y
Sporadic Pick's disease: a tauopathy characterized by a spectrum of pathological tau isoforms in gray and white matter.
Annals of neurology 2002;51(6):730-9.
2002: Green E K; Harris J M; Lemmon H; Lambert J C; Chartier-Harlin M C; St Clair D; Mann D M A; Iwatsubo T; Lendon C L
Are interleukin-1 gene polymorphisms risk factors or disease modifiers in AD?
Neurology 2002;58(10):1566-8.
2002: Green E K; Thaker U; McDonagh A M; Iwatsubo T; Lambert J-C; Chartier-Harlin M-C; Harris J M; Pickering-Brown S M; Lendon C L; Mann D M A
A polymorphism within intron 11 of the tau gene is not increased in frequency in patients with sporadic Alzheimer's disease, nor does it influence the extent of tau pathology in the brain.
Neuroscience letters 2002;324(2):113-6.
2002: Hashimoto Tadafumi; Wakabayashi Tomoko; Watanabe Atsushi; Kowa Hisatomo; Hosoda Ritsuko; Nakamura Atsushi; Kanazawa Ichiro; Arai Takao; Takio Koji; Mann David M A; Iwatsubo Takeshi
CLAC: a novel Alzheimer amyloid plaque component derived from a transmembrane precursor, CLAC-P/collagen type XXV.
The EMBO journal 2002;21(7):1524-34.
2002: Pickering-Brown S M; Richardson A M T; Snowden J S; McDonagh A M; Burns A; Braude W; Baker M; Liu W-K; Yen S-H; Hardy J; Hutton M; Davies Y; Allsop D; Craufurd D; Neary D; Mann D M A
Inherited frontotemporal dementia in nine British families associated with intronic mutations in the tau gene.
Brain : a journal of neurology 2002;125(Pt 4):732-51.
2002: Snowden Julie S; Neary David; Mann David M A
Frontotemporal dementia.
The British journal of psychiatry : the journal of mental science 2002;180():140-3.
2001: Mann D M; Takeuchi A; Sato S; Cairns N J; Lantos P L; Rossor M N; Haltia M; Kalimo H; Iwatsubo T
Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques.
Neuropathology and applied neurobiology 2001;27(3):189-96.
2001: Houlden H; Baker M; Morris H R; MacDonald N; Pickering-Brown S; Adamson J; Lees A J; Rossor M N; Quinn N P; Kertesz A; Khan M N; Hardy J; Lantos P L; St George-Hyslop P; Munoz D G; Mann D; Lang A E; Bergeron C; Bigio E H; Litvan I; Bhatia K P; Dickson D; Wood N W; Hutton M
Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype.
Neurology 2001;56(12):1702-6.
2001: Lambert J C; Harris J M; Mann D; Lemmon H; Coates J; Cumming A; St-Clair D; Lendon C
Are the estrogen receptors involved in Alzheimer's disease?
Neuroscience letters 2001;306(3):193-7.
2001: Mann D M; Pickering-Brown S M; Takeuchi A; Iwatsubo T;
Amyloid angiopathy and variability in amyloid beta deposition is determined by mutation position in presenilin-1-linked Alzheimer's disease.
The American journal of pathology 2001;158(6):2165-75.
2001: Lambert J C; Mann D M; Harris J M; Chartier-Harlin M C; Cumming A; Coates J; Lemmon H; StClair D; Iwatsubo T; Lendon C
The -48 C/T polymorphism in the presenilin 1 promoter is associated with an increased risk of developing Alzheimer's disease and an increased Abeta load in brain.
Journal of medical genetics 2001;38(6):353-5.
2001: Mann D M
Anosmia in dementia is associated with Lewy bodies rather than Alzheimer's pathology.
Journal of neurology, neurosurgery, and psychiatry 2001;70(6):720-1.
2001: Mann D M; McDonagh A M; Pickering-Brown S M; Kowa H; Iwatsubo T
Amyloid beta protein deposition in patients with frontotemporal lobar degeneration: relationship to age and apolipoprotein E genotype.
Neuroscience letters 2001;304(3):161-4.
2001: Lambert J C; Mann D; Goumidi L; Harris J; Amouyel P; Iwatsubo T; Lendon C; Chartier-Harlin M C
Effect of the APOE promoter polymorphisms on cerebral amyloid peptide deposition in Alzheimer's disease.
Lancet 2001;357(9256):608-9.
2001: Sieradzan K A; Mann D M
The selective vulnerability of nerve cells in Huntington's disease.
Neuropathology and applied neurobiology 2001;27(1):1-21.
2001: Russ C; Lovestone S; Baker M; Pickering-Brown S M; Andersen P M; Furlong R; Mann D; Powell J F
The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease.
Neuroscience letters 2001;299(1-2):156-8.
2001: Jefferson M F; Burlinson S; Burns A; Mann D; Pickering-Brown S; Owen F; Sriwardhana C; Pendleton N; Horan M A
Clinical features of dementia associated with apolipoprotein epsilon4: discrimination with a neural network genetic algorithm.
International journal of geriatric psychiatry 2001;16(1):77-81.
2000: Pickering-Brown S; Baker M; Yen S H; Liu W K; Hasegawa M; Cairns N; Lantos P L; Rossor M; Iwatsubo T; Davies Y; Allsop D; Furlong R; Owen F; Hardy J; Mann D; Hutton M
Pick's disease is associated with mutations in the tau gene.
Annals of neurology 2000;48(6):859-67.
2000: Neary D; Snowden J S; Mann D M
Cognitive change in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS).
Journal of the neurological sciences 2000;180(1-2):15-20.
2000: Lambert J C; Mann D; Goumidi L; Harris J; Pasquier F; Frigard B; Cottel D; Lendon C; Iwatsubo T; Amouyel P; Chartier-Harlin M C
A FE65 polymorphism associated with risk of developing sporadic late-onset alzheimer's disease but not with Abeta loading in brains.
Neuroscience letters 2000;293(1):29-32.
2000: Lambert J C; Goumidi L; Vrièze F W; Frigard B; Harris J M; Cummings A; Coates J; Pasquier F; Cottel D; Gaillac M; St Clair D; Mann D M; Hardy J; Lendon C L; Amouyel P; Chartier-Harlin M C
The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease.
Human molecular genetics 2000;9(15):2275-80.
2000: Takeuchi A; Irizarry M C; Duff K; Saido T C; Hsiao Ashe K; Hasegawa M; Mann D M; Hyman B T; Iwatsubo T
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss.
The American journal of pathology 2000;157(1):331-9.
2000: Pickering-Brown S M; Owen F; Isaacs A; Snowden J; Varma A; Neary D; Furlong R; Daniel S E; Cairns N J; Mann D M
Apolipoprotein E epsilon4 allele has no effect on age at onset or duration of disease in cases of frontotemporal dementia with pick- or microvacuolar-type histology.
Experimental neurology 2000;163(2):452-6.
2000: McCarron M O; Nicoll J A; Stewart J; Cole G M; Yang F; Ironside J W; Mann D M; Love S; Graham D I
Amyloid beta-protein length and cerebral amyloid angiopathy-related haemorrhage.
Neuroreport 2000;11(5):937-40.
2000: Corrigan F M; Wienburg C L; Shore R F; Daniel S E; Mann D
Organochlorine insecticides in substantia nigra in Parkinson's disease.
Journal of toxicology and environmental health. Part A 2000;59(4):229-34.
2000: Mann D M; McDonagh A M; Snowden J; Neary D; Pickering-Brown S M
Molecular classification of the dementias.
Lancet 2000;355(9204):626.
2000: McCarron M O; Nicoll J A; Stewart J; Ironside J W; Mann D M; Love S; Graham D I; Grubb A
Absence of cystatin C mutation in sporadic cerebral amyloid angiopathy-related hemorrhage.
Neurology 2000;54(1):242-4.
2000: Neary D; Snowden J S; Mann D M
Classification and description of frontotemporal dementias.
Annals of the New York Academy of Sciences 2000;920():46-51.
1999: Lippa C F; Ozawa K; Mann D M; Ishii K; Smith T W; Arawaka S; Mori H
Deposition of beta-amyloid subtypes 40 and 42 differentiates dementia with Lewy bodies from Alzheimer disease.
Archives of neurology 1999;56(9):1111-8.
1999: McGowan E; Sanders S; Iwatsubo T; Takeuchi A; Saido T; Zehr C; Yu X; Uljon S; Wang R; Mann D; Dickson D; Duff K
Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.
Neurobiology of disease 1999;6(4):231-44.
1999: Houlden H; Baker M; Adamson J; Grover A; Waring S; Dickson D; Lynch T; Boeve B; Petersen R C; Pickering-Brown S; Owen F; Neary D; Craufurd D; Snowden J; Mann D; Hutton M
Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia.
Annals of neurology 1999;46(2):243-8.
1999: Romero I; Jørgensen P; Bolwig G; Fraser P E; Rogaeva E; Mann D; Havsager A M; Jørgensen A L
A presenilin-1 Thr116Asn substitution in a family with early-onset Alzheimer's disease.
Neuroreport 1999;10(11):2255-60.
1999: Wu C; Singh S K; Dias P; Kumar S; Mann D M
Activated astrocytes display increased 5-HT2a receptor expression in pathological states.
Experimental neurology 1999;158(2):529-33.
1999: McCarron M O; Nicoll J A; Stewart J; Ironside J W; Mann D M; Love S; Graham D I; Dewar D
The apolipoprotein E epsilon2 allele and the pathological features in cerebral amyloid angiopathy-related hemorrhage.
Journal of neuropathology and experimental neurology 1999;58(7):711-8.
1999: Sieradzan K A; Mechan A O; Jones L; Wanker E E; Nukina N; Mann D M
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein.
Experimental neurology 1999;156(1):92-9.
1999: Houlden H; Rizzu P; Stevens M; de Knijff P; van Duijn C M; van Swieten J C; Heutink P; Perez-Tur J; Thomas V; Baker M; Morris H; Rossor M; Jannsen J C; Petersen R C; Dodd P; Dark F; Boeve B; Dickson D; Davies P; Pickering-Brown S; Mann D; Adamson J; Lynch T; Payami H; Hardy J
Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations.
Neuroscience letters 1999;260(3):193-5.
1999: Varma A R; Snowden J S; Lloyd J J; Talbot P R; Mann D M; Neary D
Evaluation of the NINCDS-ADRDA criteria in the differentiation of Alzheimer's disease and frontotemporal dementia.
Journal of neurology, neurosurgery, and psychiatry 1999;66(2):184-8.
1998: Hosoda R; Saido T C; Otvos L; Arai T; Mann D M; Lee V M; Trojanowski J Q; Iwatsubo T
Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains.
Journal of neuropathology and experimental neurology 1998;57(11):1089-95.
1998: Lippa C F; Fujiwara H; Mann D M; Giasson B; Baba M; Schmidt M L; Nee L E; O'Connell B; Pollen D A; St George-Hyslop P; Ghetti B; Nochlin D; Bird T D; Cairns N J; Lee V M; Iwatsubo T; Trojanowski J Q
Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes.
The American journal of pathology 1998;153(5):1365-70.
1998: Lambert J C; Berr C; Pasquier F; Delacourte A; Frigard B; Cottel D; Pérez-Tur J; Mouroux V; Mohr M; Cécyre D; Galasko D; Lendon C; Poirier J; Hardy J; Mann D; Amouyel P; Chartier-Harlin M C
Pronounced impact of Th1/E47cs mutation compared with -491 AT mutation on neural APOE gene expression and risk of developing Alzheimer's disease.
Human molecular genetics 1998;7(9):1511-6.
1998: Sieradzan K A; Mann D M
On the pathological progression of Huntington's disease.
Annals of neurology 1998;44(1):148-9.
1998: Mann D M; Brown S M; Owen F; Baba M; Iwatsubo T
Amyloid beta protein (A beta) deposition in dementia with Lewy bodies: predominance of A beta 42(43) and paucity of A beta 40 compared with sporadic Alzheimer's disease.
Neuropathology and applied neurobiology 1998;24(3):187-94.
1998: Hutton M; Lendon C L; Rizzu P; Baker M; Froelich S; Houlden H; Pickering-Brown S; Chakraverty S; Isaacs A; Grover A; Hackett J; Adamson J; Lincoln S; Dickson D; Davies P; Petersen R C; Stevens M; de Graaff E; Wauters E; van Baren J; Hillebrand M; Joosse M; Kwon J M; Nowotny P; Che L K; Norton J; Morris J C; Reed L A; Trojanowski J; Basun H; Lannfelt L; Neystat M; Fahn S; Dark F; Tannenberg T; Dodd P R; Hayward N; Kwok J B; Schofield P R; Andreadis A; Snowden J; Craufurd D; Neary D; Owen F; Oostra B A; Hardy J; Goate A; van Swieten J; Mann D; Lynch T; Heutink P
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17.
Nature 1998;393(6686):702-5.
1998: Mann D M
Dementia of frontal type and dementias with subcortical gliosis.
Brain pathology (Zurich, Switzerland) 1998;8(2):325-38.
1998: Burlinson S; Burns A; Mann D; Pickering-Brown S; Owen F
Effect of apolipoprotein E status on clinical features of dementia.
International journal of geriatric psychiatry 1998;13(3):177-85.
1997: Lambert J C; Pérez-Tur J; Dupire M J; Galasko D; Mann D; Amouyel P; Hardy J; Delacourte A; Chartier-Harlin M C
Distortion of allelic expression of apolipoprotein E in Alzheimer's disease.
Human molecular genetics 1997;6(12):2151-4.
1997: Galvin J E; Lee V M; Baba M; Mann D M; Dickson D W; Yamaguchi H; Schmidt M L; Iwatsubo T; Trojanowski J Q
Monoclonal antibodies to purified cortical Lewy bodies recognize the mid-size neurofilament subunit.
Annals of neurology 1997;42(4):595-603.
1997: Mann D M
Molecular biology's impact on our understanding of aging.
BMJ (Clinical research ed.) 1997;315(7115):1078-81.
1997: Burns A; Tomlinson B E; Mann D M
Observations on the brains of demented old people. B.E. Tomlinson, G. Blessed and M. Roth, Journal of the Neurological Sciences (1970) 11, 205-242 and Observations on the brains of non-demented old people. B.E. Tomlinson, G. Blessed and M. Roth, Journal of Neurological Sciences (1968) 7, 331-356.
International journal of geriatric psychiatry 1997;12(8):785-90.
1997: Mann D M
A commentary on the diagnostic criteria for the neuropathological assessment of Alzheimer's disease.
Neurobiology of aging 1997;18(4 Suppl):S51-2.
1997: Sieradzan K; Mann D M; Dodge A
Clinical presentation and patterns of regional cerebral atrophy related to the length of trinucleotide repeat expansion in patients with adult onset Huntington's disease.
Neuroscience letters 1997;225(1):45-8.
1997: Mann D M; Pickering-Brown S M; Bayatti N N; Wright A E; Owen F; Iwatsubo T; Saido T C
An intronic polymorphism in the presenilin-1 gene does not influence the amount or molecular form of the amyloid beta protein deposited in Alzheimer's disease.
Neuroscience letters 1997;222(1):57-60.
1997: Mann D M; Iwatsubo T; Pickering-Brown S M; Owen F; Saido T C; Perry R H
Preferential deposition of amyloid beta protein (Abeta) in the form Abeta40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele.
Neuroscience letters 1997;221(2-3):81-4.
1997: Mann D M; Iwatsubo T; Nochlin D; Sumi S M; Levy-Lahad E; Bird T D
Amyloid (Abeta) deposition in chromosome 1-linked Alzheimer's disease: the Volga German families.
Annals of neurology 1997;41(1):52-7.
1996: Mann D M
Pyramidal nerve cell loss in Alzheimer's disease.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(4):423-7.
1996: Iwatsubo T; Saido T C; Mann D M; Lee V M; Trojanowski J Q
Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques.
The American journal of pathology 1996;149(6):1823-30.
1996: Barton A J; Crook B W; Karran E H; Brown F; Dewar D; Mann D M; Pearson R C; Graham D I; Hardy J; Hutton M; Duff K; Goate A M; Clark R F; Roberts G W
Alteration in brain presenilin 1 mRNA expression in early onset familial Alzheimer's disease.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(3):213-8.
1996: Cooper P N; Jackson M; Lennox G; Lowe L; Mann D M
Brain-stem inclusions in motor neuron disease-type dementia.
Archives of neurology 1996;53(9):836.
1996: Mann D M; Iwatsubo T; Cairns N J; Lantos P L; Nochlin D; Sumi S M; Bird T D; Poorkaj P; Hardy J; Hutton M; Prihar G; Crook R; Rossor M N; Haltia M
Amyloid beta protein (Abeta) deposition in chromosome 14-linked Alzheimer's disease: predominance of Abeta42(43).
Annals of neurology 1996;40(2):149-56.
1996: Mann D M; Iwatsubo T
Diffuse plaques in the cerebellum and corpus striatum in Down's syndrome contain amyloid beta protein (A beta) only in the form of A beta 42(43).
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1996;5(2):115-20.
1996: Cataldo A M; Barnett J L; Mann D M; Nixon R A
Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome.
Journal of neuropathology and experimental neurology 1996;55(6):704-15.
1996: Siddons M A; Pickering-Brown S M; Mann D M; Owen F; Cooper P N
Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis.
Neuroscience letters 1996;208(1):65-8.
1996: Mann D M; Iwatsubo T; Ihara Y; Cairns N J; Lantos P L; Bogdanovic N; Lannfelt L; Winblad B; Maat-Schieman M L; Rossor M N
Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene.
The American journal of pathology 1996;148(4):1257-66.
1996: Cooper P N; Siddons C A; Mann D M
Patterns of glial cell activity in fronto-temporal dementia (lobar atrophy).
Neuropathology and applied neurobiology 1996;22(1):17-22.
1996: Royston M C; Mann D; Pickering-Brown S; Owen F; Perry R; Ragbavan R; Khin-Nu C; Tyner S; Day K; Crook R; Hardy J; Roberts G W
ApoE2 allele, Down's syndrome, and dementia.
Annals of the New York Academy of Sciences 1996;777():255-9.
1996: Teller J K; Russo C; DeBusk L M; Angelini G; Zaccheo D; Dagna-Bricarelli F; Scartezzini P; Bertolini S; Mann D M; Tabaton M; Gambetti P
Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome.
Nature medicine 1996;2(1):93-5.
1996: Mann D M; Iwatsubo T; Snowden J S
Atypical amyloid (A beta) deposition in the cerebellum in Alzheimer's disease: an immunohistochemical study using end-specific A beta monoclonal antibodies.
Acta neuropathologica 1996;91(6):647-53.
1995: Cooper P N; Siddons M; Mann D M
Normal frontal cortex histology and immunohistochemistry in patients with motor neuron disease.
Journal of neurology, neurosurgery, and psychiatry 1995;59(6):644.
1995: Qume M; Misra A; Zeman S; Boddy J L; Cross A J; Francis P T; Procter A W; Mann D M; Bowen D M
Non-serotonergic profiles of lobar atrophies.
Biochemical Society transactions 1995;23(4):601S.
1995: Cooper P N; Jackson M; Lennox G; Lowe J; Mann D M
Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia.
Archives of neurology 1995;52(10):1011-5.
1995: Mann D M; Pickering-Brown S M; Siddons M A; Iwatsubo T; Ihara Y; Asami-Odaka A; Suzuki N
The extent of amyloid deposition in brain in patients with Down's syndrome does not depend upon the apolipoprotein E genotype.
Neuroscience letters 1995;196(1-2):105-8.
1995: Manaye K F; McIntire D D; Mann D M; German D C
Locus coeruleus cell loss in the aging human brain: a non-random process.
The Journal of comparative neurology 1995;358(1):79-87.
1995: Hyman B T; West H L; Rebeck G W; Lai F; Mann D M
Neuropathological changes in Down's syndrome hippocampal formation. Effect of age and apolipoprotein E genotype.
Archives of neurology 1995;52(4):373-8.
1995: Pickering-Brown S M; Mann D M; Owen F; Ironside J W; de Silva R; Roberts D A; Balderson D J; Cooper P N
Allelic variations in apolipoprotein E and prion protein genotype related to plaque formation and age of onset in sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 1995;187(2):127-9.
1995: Iwatsubo T; Mann D M; Odaka A; Suzuki N; Ihara Y
Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome.
Annals of neurology 1995;37(3):294-9.
1995: Pickering-Brown S M; Siddons M; Mann D M; Owen F; Neary D; Snowden J S
Apolipoprotein E allelic frequencies in patients with lobar atrophy.
Neuroscience letters 1995;188(3):205-7.
1995: Saido T C; Iwatsubo T; Mann D M; Shimada H; Ihara Y; Kawashima S
Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.
Neuron 1995;14(2):457-66.
1995: Mann D M; Iwatsubo T; Fukumoto H; Ihara Y; Odaka A; Suzuki N
Microglial cells and amyloid beta protein (A beta) deposition; association with A beta 40-containing plaques.
Acta neuropathologica 1995;90(5):472-7.
1995: Mann D M; Snowden J S
The topographic distribution of brain atrophy in cortical Lewy body disease: comparison with Alzheimer's disease.
Acta neuropathologica 1995;89(2):178-83.
1994: Royston M C; Mann D; Pickering-Brown S; Owen F; Perry R; Raghavan R; Khin-Nu C; Tyrer S; Day K; Crook R
Apolipoprotein E epsilon 2 allele promotes longevity and protects patients with Down's syndrome from dementia.
Neuroreport 1994;5(18):2583-5.
1994: Webster M T; Francis P T; Procter A W; Stratmann G C; Doshi R; Mann D M; Bowen D M
Postmortem brains reveal similar but not identical amyloid precursor protein-like immunoreactivity in Alzheimer compared with other dementias.
Brain research 1994;644(2):347-51.
1994: Mann D M
Pathological correlates of dementia in Alzheimer's disease.
Neurobiology of aging 1994;15(3):357-60; discussion 379-80.
1994: Pickering-Brown S M; Mann D M; Bourke J P; Roberts D A; Balderson D; Burns A; Byrne J; Owen F
Apolipoprotein E4 and Alzheimer's disease pathology in Lewy body disease and in other beta-amyloid-forming diseases.
Lancet 1994;343(8906):1155.
1994: Procter A W; Francis P T; Holmes C; Webster M T; Qume M; Stratmann G C; Doshi R; Mann D M; Harrison P J; Pearson R C
beta-Amyloid precursor protein isoforms show correlations with neurones but not with glia of demented subjects.
Acta neuropathologica 1994;88(6):545-52.
1993: Davies C A; Mann D M
Is the "preamyloid" of diffuse plaques in Alzheimer's disease really nonfibrillar?
The American journal of pathology 1993;143(6):1594-605.
1993: Clinton J; Mann D M; Roberts G W
Frontal lobe dementia is not a variant of prion disease.
Neuroscience letters 1993;164(1-2):1-4.
1993: Neary D; Snowden J S; Mann D M
Familial progressive aphasia: its relationship to other forms of lobar atrophy.
Journal of neurology, neurosurgery, and psychiatry 1993;56(10):1122-5.
1993: Mann D M; South P W; Snowden J S; Neary D
Dementia of frontal lobe type: neuropathology and immunohistochemistry.
Journal of neurology, neurosurgery, and psychiatry 1993;56(6):605-14.
1993: Neary D; Snowden J S; Mann D M
The clinical pathological correlates of lobar atrophy.
Dementia (Basel, Switzerland) 1993;4(3-4):154-9.
1993: Francis P T; Webster M T; Procter A W; Clarke N A; Bowen D M; Doshi R; Mann D M; Neary D
Soluble beta-amyloid precursor protein and pyramidal neuron loss.
Lancet 1993;341(8842):431.
1993: Mann D M; Oliver R; Snowden J S
The topographic distribution of brain atrophy in Huntington's disease and progressive supranuclear palsy.
Acta neuropathologica 1993;85(5):553-9.
1993: Mann D M; South P W
The topographic distribution of brain atrophy in frontal lobe dementia.
Acta neuropathologica 1993;85(3):334-40.
1992: German D C; Manaye K F; White C L; Woodward D J; McIntire D D; Smith W K; Kalaria R N; Mann D M
Disease-specific patterns of locus coeruleus cell loss.
Annals of neurology 1992;32(5):667-76.
1992: Hanger D P; Mann D M; Neary D; Anderton B H
Tau pathology in a case of familial Alzheimer's disease with a valine to glycine mutation at position 717 in the amyloid precursor protein.
Neuroscience letters 1992;145(2):178-80.
1992: Hanger D P; Mann D M; Neary D; Anderton B H
Molecular pathology of Alzheimer's disease in sporadic and familial Alzheimer's disease with mutations in the amyloid precursor protein.
Biochemical Society transactions 1992;20(3):642-5.
1992: Bowen D M; Francis P T; Procter A W; Halliwell J V; Mann D M; Neary D
Treatment strategy for the corticocortical neuron pathology of Alzheimer's disease.
Annals of neurology 1992;32(1):112.
1992: Wightman G; Anderson V E; Martin J; Swash M; Anderton B H; Neary D; Mann D; Luthert P; Leigh P N
Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia.
Neuroscience letters 1992;139(2):269-74.
1992: Mann D M; Jones D; Snowden J S; Neary D; Hardy J
Pathological changes in the brain of a patient with familial Alzheimer's disease having a missense mutation at codon 717 in the amyloid precursor protein gene.
Neuroscience letters 1992;137(2):225-8.
1992: Snowden J S; Neary D; Mann D M; Goulding P J; Testa H J
Progressive language disorder due to lobar atrophy.
Annals of neurology 1992;31(2):174-83.
1992: Mann D M; Purkiss M S; Bonshek R E; Jones D; Brown A M; Stoddart R W
Lectin histochemistry of cerebral microvessels in ageing, Alzheimer's disease and Down's syndrome.
Neurobiology of aging 1992;13(1):137-43.
1992: Davies D C; Horwood N; Isaacs S L; Mann D M
The effect of age and Alzheimer's disease on pyramidal neuron density in the individual fields of the hippocampal formation.
Acta neuropathologica 1992;83(5):510-7.
1992: Mann D M; Jones D; South P W; Snowden J S; Neary D
Deposition of amyloid beta protein in non-Alzheimer dementias: evidence for a neuronal origin of parenchymal deposits of beta protein in neurodegenerative disease.
Acta neuropathologica 1992;83(4):415-9.
1991: Mann D M
Is the pattern of nerve cell loss in aging and Alzheimer's disease a real, or only an apparent, selectivity?
Neurobiology of aging 1991;12(4):340-3; discussion 352-5.
1991: Guy S P; Jones D; Mann D M; Itzhaki R F
Human neuroblastoma cells treated with aluminium express an epitope associated with Alzheimer's disease neurofibrillary tangles.
Neuroscience letters 1991;121(1-2):166-8.
1991: Mann D M
The topographic distribution of brain atrophy in Alzheimer's disease.
Acta neuropathologica 1991;83(1):81-6.
1990: Mann D M; Royston M C; Ravindra C R
Some morphometric observations on the brains of patients with Down's syndrome: their relationship to age and dementia.
Journal of the neurological sciences 1990;99(2-3):153-64.
1990: Kobayashi K; Emson P C; Mountjoy C Q; Thornton S N; Lawson D E; Mann D M
Cerebral cortical calbindin D28K and parvalbumin neurones in Down's syndrome.
Neuroscience letters 1990;113(1):17-22.
1990: Flament S; Delacourte A; Mann D M
Phosphorylation of Tau proteins: a major event during the process of neurofibrillary degeneration. A comparative study between Alzheimer's disease and Down's syndrome.
Brain research 1990;516(1):15-9.
1990: Davies C A; Morroll D R; Prinja D; Mann D M; Gibbs A
A quantitative assessment of somatostatin-like and neuropeptide Y-like immunostained cells in the frontal and temporal cortex of patients with Alzheimer's disease.
Journal of the neurological sciences 1990;96(1):59-73.
1990: Mann D M; Brown A M; Prinja D; Jones D; Davies C A
A morphological analysis of senile plaques in the brains of non-demented persons of different ages using silver, immunocytochemical and lectin histochemical staining techniques.
Neuropathology and applied neurobiology 1990;16(1):17-25.
1990: Mann D M; Jones D
Deposition of amyloid (A4) protein within the brains of persons with dementing disorders other than Alzheimer's disease and Down's syndrome.
Neuroscience letters 1990;109(1-2):68-75.
1990: Neary D; Snowden J S; Mann D M; Northen B; Goulding P J; Macdermott N
Frontal lobe dementia and motor neuron disease.
Journal of neurology, neurosurgery, and psychiatry 1990;53(1):23-32.
1990: Gibb W R; Mann D M; Mountjoy C Q; Lees A J
A pathological study of the association between Lewy body disease and Alzheimer's disease.
Advances in neurology 1990;53():55-9.
1990: Mann D M; Jones D; Prinja D; Purkiss M S
The prevalence of amyloid (A4) protein deposits within the cerebral and cerebellar cortex in Down's syndrome and Alzheimer's disease.
Acta neuropathologica 1990;80(3):318-27.
1989: Allsop D; Haga S I; Haga C; Ikeda S I; Mann D M; Ishii T
Early senile plaques in Down's syndrome brains show a close relationship with cell bodies of neurons.
Neuropathology and applied neurobiology 1989;15(6):531-42.
1989: Mann D M; Prinja D; Davies C A; Ihara Y; Delacourte A; Défossez A; Mayer R J; Landon M
Immunocytochemical profile of neurofibrillary tangles in Down's syndrome patients of different ages.
Journal of the neurological sciences 1989;92(2-3):247-60.
1989: Mann D M
Cerebral amyloidosis, ageing and Alzheimer's disease; a contribution from studies on Down's syndrome.
Neurobiology of aging 1989;10(5):397-9; discussion 412-4.
1989: Mann D M; Brown A; Prinja D; Davies C A; Landon M; Masters C L; Beyreuthers K
An analysis of the morphology of senile plaques in Down's syndrome patients of different ages using immunocytochemical and lectin histochemical techniques.
Neuropathology and applied neurobiology 1989;15(4):317-29.
1989: Gibb W R; Mountjoy C Q; Mann D M; Lees A J
A pathological study of the association between Lewy body disease and Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1989;52(6):701-8.
1989: Simpson M D; Slater P; Cross A J; Mann D M; Royston M C; Deakin J F; Reynolds G P
Reduced D-[3H]aspartate binding in Down's syndrome brains.
Brain research 1989;484(1-2):273-8.
1989: Mann D M
Neuropathology of Alzheimer's disease: towards an understanding of the pathogenesis.
Biochemical Society transactions 1989;17(1):73-5.
1989: Gibb W R; Mountjoy C Q; Mann D M; Lees A J
The substantia nigra and ventral tegmental area in Alzheimer's disease and Down's syndrome.
Journal of neurology, neurosurgery, and psychiatry 1989;52(2):193-200.
1989: Mann D M; Esiri M M
The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome.
Journal of the neurological sciences 1989;89(2-3):169-79.
1989: Marcyniuk B; Mann D M; Yates P O
The topography of nerve cell loss from the locus caeruleus in elderly persons.
Neurobiology of aging 1989;10(1):5-9.
1989: Mann D M
The site and nature of the primary lesions in Alzheimer's disease.
Progress in clinical and biological research 1989;317():303-11.
1989: Mann D M
The pathogenesis and progression of the pathological changes of Alzheimer's disease.
Annals of medicine 1989;21(2):133-6.
1989: Mann D M; Brandt P; Sisken B; Vanaman T C
Identification of a synaptic membrane-localized isoform of the calcium-pumping ATPase.
Advances in experimental medicine and biology 1989;255():71-8.
1989: Mann D M; Brown A; Wilks D P; Davies C A
Immunocytochemical and lectin histochemical studies of plaques and tangles in Down's syndrome patients at different ages.
Progress in clinical and biological research 1989;317():849-56.
1989: Mann D M
Subcortical afferent projection systems in Huntington's chorea.
Acta neuropathologica 1989;78(5):551-4.
1988: Davies D C; Wilmott A C; Mann D M
Senile plaques are concentrated in the subicular region of the hippocampal formation in Alzheimer's disease.
Neuroscience letters 1988;94(1-2):228-33.
1988: Mann D M; Yates P O; Marcyniuk B
Pathologic heterogeneity of Alzheimer's disease.
Archives of general psychiatry 1988;45(10):962-3.
1988: Simpson M D; Royston M C; Deakin J F; Cross A J; Mann D M; Slater P
Regional changes in [3H]D-aspartate and [3H]TCP binding sites in Alzheimer's disease brains.
Brain research 1988;462(1):76-82.
1988: Mayes A R; Meudell P R; Mann D; Pickering A
Location of lesions in Korsakoff's syndrome: neuropsychological and neuropathological data on two patients.
Cortex; a journal devoted to the study of the nervous system and behavior 1988;24(3):367-88.
1988: Mann D M
Alzheimer's disease and Down's syndrome.
Histopathology 1988;13(2):125-37.
1988: Mann D M; Marcyniuk B; Yates P O; Neary D; Snowden J S
The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy.
Neuropathology and applied neurobiology 1988;14(3):177-95.
1988: Mann D M
The pathological association between Down syndrome and Alzheimer disease.
Mechanisms of ageing and development 1988;43(2):99-136.
1988: Mann D M; Esiri M M
The site of the earliest lesions of Alzheimer's disease.
The New England journal of medicine 1988;318(12):789-90.
1988: Mann D M; Bonshek R E; Marcyniuk B; Stoddart R W; Torgerson E
Saccharides of senile plaques and neurofibrillary tangles in Alzheimer's disease.
Neuroscience letters 1988;85(2):277-82.
1988: Mann D M; Tucker C M; Yates P O
Alzheimer's disease: an olfactory connection?
Mechanisms of ageing and development 1988;42(1):1-15.
1988: Marcyniuk B; Mann D M; Yates P O; Ravindra C R
Topography of nerve cell loss from the locus caeruleus in middle aged persons with Down's syndrome.
Journal of the neurological sciences 1988;83(1):15-24.
1988: Mann D M
Calcification of the basal ganglia in Down's syndrome and Alzheimer's disease.
Acta neuropathologica 1988;76(6):595-8.
1987: Mann D M
Neuronal loss in old people: the effects of ageing or disease?
Neurobiology of aging 1987;8(6):550-1.
1987: Mann D M; Yates P O; Marcyniuk B; Ravindra C R
Loss of neurones from cortical and subcortical areas in Down's syndrome patients at middle age. Quantitative comparisons with younger Down's patients and patients with Alzheimer's disease.
Journal of the neurological sciences 1987;80(1):79-89.
1987: Palmer A M; Francis P T; Bowen D M; Benton J S; Neary D; Mann D M; Snowden J S
Catecholaminergic neurones assessed ante-mortem in Alzheimer's disease.
Brain research 1987;414(2):365-75.
1987: Mann D M; Yates P O
The perforant pathway in Down's syndrome.
Annals of neurology 1987;21(6):613-4.
1987: Davies C A; Mann D M; Sumpter P Q; Yates P O
A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.
Journal of the neurological sciences 1987;78(2):151-64.
1987: Mann D M; Tucker C M; Yates P O
The topographic distribution of senile plaques and neurofibrillary tangles in the brains of non-demented persons of different ages.
Neuropathology and applied neurobiology 1987;13(2):123-39.
1987: Francis P T; Bowen D M; Lowe S L; Neary D; Mann D M; Snowden J S
Somatostatin content and release measured in cerebral biopsies from demented patients.
Journal of the neurological sciences 1987;78(1):1-16.
1987: Mann D M; Yates P O; Marcyniuk B
Dopaminergic neurotransmitter systems in Alzheimer's disease and in Down's syndrome at middle age.
Journal of neurology, neurosurgery, and psychiatry 1987;50(3):341-4.
1987: Palmer A M; Francis P T; Benton J S; Sims N R; Mann D M; Neary D; Snowden J S; Bowen D M
Presynaptic serotonergic dysfunction in patients with Alzheimer's disease.
Journal of neurochemistry 1987;48(1):8-15.
1987: Mann D; Vanaman T C
Specific chemical modification as a probe of calmodulin function.
Methods in enzymology 1987;139():417-33.
1987: Mann D M; Sumpter P Q; Davies C A; Yates P O
Glycogen accumulations in the cerebral cortex in Alzheimer's disease.
Acta neuropathologica 1987;73(2):181-4.
1986: Marcyniuk B; Mann D M; Yates P O
The topography of cell loss from locus caeruleus in Alzheimer's disease.
Journal of the neurological sciences 1986;76(2-3):335-45.
1986: Hardy J A; Mann D M; Wester P; Winblad B
An integrative hypothesis concerning the pathogenesis and progression of Alzheimer's disease.
Neurobiology of aging 1986;7(6):489-502.
1986: Mann D M; Eaves N R; Marcyniuk B; Yates P O
Quantitative changes in cerebral cortical microvasculature in ageing and dementia.
Neurobiology of aging 1986;7(5):321-30.
1986: Mann D M; Yates P O; Marcyniuk B; Ravindra C R
The topography of plaques and tangles in Down's syndrome patients of different ages.
Neuropathology and applied neurobiology 1986;12(5):447-57.
1986: Sumpter P Q; Mann D M; Davies C A; Neary D; Snowden J S; Yates P O
A quantitative study of the ultrastructure of pyramidal neurons of the cerebral cortex in Alzheimer's disease in relationship to the degree of dementia.
Neuropathology and applied neurobiology 1986;12(3):321-9.
1986: Sumpter P Q; Mann D M; Davies C A; Yates P O; Snowden J S; Neary D
An ultrastructural analysis of the effects of accumulation of neurofibrillary tangle in pyramidal neurons of the cerebral cortex in Alzheimer's disease.
Neuropathology and applied neurobiology 1986;12(3):305-19.
1986: Marcyniuk B; Mann D M; Yates P O
Loss of nerve cells from locus coeruleus in Alzheimer's disease is topographically arranged.
Neuroscience letters 1986;64(3):247-52.
1986: Mann D M; Yates P O; Marcyniuk B
A comparison of nerve cell loss in cortical and subcortical structures in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1986;49(3):310-2.
1986: Neary D; Snowden J S; Mann D M; Bowen D M; Sims N R; Northen B; Yates P O; Davison A N
Alzheimer's disease: a correlative study.
Journal of neurology, neurosurgery, and psychiatry 1986;49(3):229-37.
1986: Neary D; Snowden J S; Bowen D M; Sims N R; Mann D M; Yates P O; Davison A N
Cerebral biopsy in the investigation of presenile dementia due to cerebral atrophy.
Journal of neurology, neurosurgery, and psychiatry 1986;49(2):157-62.
1986: Neary D; Snowden J S; Bowen D M; Sims N R; Mann D M; Benton J S; Northen B; Yates P O; Davison A N
Neuropsychological syndromes in presenile dementia due to cerebral atrophy.
Journal of neurology, neurosurgery, and psychiatry 1986;49(2):163-74.
1986: Mann D M; Yates P O; Marcyniuk B
The nucleus basalis of Meynert in multi-infarct (vascular) dementia.
Acta neuropathologica 1986;71(3-4):332-7.
1986: Mann D M; Yates P O
Neurotransmitter deficits in Alzheimer's disease and in other dementing disorders.
Human neurobiology 1986;5(3):147-58.
1985: Mann D M
The neuropathology of Alzheimer's disease: a review with pathogenetic, aetiological and therapeutic considerations.
Mechanisms of ageing and development 1985;31(3):213-55.
1985: Mann D M; Yates P O; Marcyniuk B
Some morphometric observations on the cerebral cortex and hippocampus in presenile Alzheimer's disease, senile dementia of Alzheimer type and Down's syndrome in middle age.
Journal of the neurological sciences 1985;69(3):139-59.
1985: Mann D M; Yates P O; Marcyniuk B; Ravindra C R
Pathological evidence for neurotransmitter deficits in Down's syndrome of middle age.
Journal of mental deficiency research 1985;29 ( Pt 2)():125-35.
1985: Mann D M; Yates P O; Marcyniuk B
Correlation between senile plaque and neurofibrillary tangle counts in cerebral cortex and neuronal counts in cortex and subcortical structures in Alzheimer's disease.
Neuroscience letters 1985;56(1):51-5.
1985: Mann D M; Yates P O; Marcyniuk B
Changes in Alzheimer's disease in the magnocellular neurones of the supraoptic and paraventricular nuclei of the hypothalamus and their relationship to the noradrenergic deficit.
Clinical neuropathology 1985;4(3):127-34.
1984: Mann D M; Yates P O; Marcyniuk B
Monoaminergic neurotransmitter systems in presenile Alzheimer's disease and in senile dementia of Alzheimer type.
Clinical neuropathology 1984;3(5):199-205.
1984: Mann D M; Yates P O; Marcyniuk B
Alzheimer's presenile dementia, senile dementia of Alzheimer type and Down's syndrome in middle age form an age related continuum of pathological changes.
Neuropathology and applied neurobiology 1984;10(3):185-207.
1984: Mann D M; Yates P O; Marcyniuk B
Changes in nerve cells of the nucleus basalis of Meynert in Alzheimer's disease and their relationship to ageing and to the accumulation of lipofuscin pigment.
Mechanisms of ageing and development 1984;25(1-2):189-204.
1984: Mann D M; Yates P O; Marcyniuk B
A comparison of changes in the nucleus basalis and locus caeruleus in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1984;47(2):201-3.
1984: Mann D M; Yates P O; Marcynuik B
Age and Alzheimer's disease.
Lancet 1984;1(8371):281-2.
1984: Mann D M; Yates P O; Marcyniuk B
Relationship between pigment accumulation and age in Alzheimer's disease and Down syndrome.
Acta neuropathologica 1984;63(1):72-7.
1983: Mann D M
The locus coeruleus and its possible role in ageing and degenerative disease of the human central nervous system.
Mechanisms of ageing and development 1983;23(1):73-94.
1983: Mann D M; Yates P O
Patterns of sleep and the noradrenergic neurotransmitter system in the elderly and the demented.
Journal of the American Geriatrics Society 1983;31(7):450-1.
1983: Mann D M; Yates P O
Possible role of neuromelanin in the pathogenesis of Parkinson's disease.
Mechanisms of ageing and development 1983;21(2):193-203.
1983: Mann D M; Yates P O
Serotonin nerve cells in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1983;46(1):96.
1983: Mann D M; Yates P O
Pathological basis for neurotransmitter changes in Parkinson's disease.
Neuropathology and applied neurobiology 1983;9(1):3-19.
1983: Mann D M; Tinkler A M; Yates P O
Neurological disease and herpes simplex virus. An immunohistochemical study.
Acta neuropathologica 1983;60(1-2):24-8.
1983: Mann D M; Yates P O; Hawkes J
The pathology of the human locus ceruleus.
Clinical neuropathology 1983;2(1):1-7.
1982: Mann D M; Yates P O
Is the loss of cerebral cortical choline acetyl transferase activity in Alzheimer's disease due to degeneration of ascending cholinergic nerve cells.
Journal of neurology, neurosurgery, and psychiatry 1982;45(10):936.
1982: Mann D M; Yates P O
Pathogenesis of Parkinson's disease.
Archives of neurology 1982;39(9):545-9.
1982: Mann D M; Yates P O; Hawkes J
Plaques and tangles and transmitter deficiencies in dementia.
Journal of neurology, neurosurgery, and psychiatry 1982;45(6):563-4.
1982: Mann D M
Nerve cell protein metabolism and degenerative disease.
Neuropathology and applied neurobiology 1982;8(3):161-76.
1982: Mann D M; Yates P O; Hawkes J
The noradrenergic system in Alzheimer and multi-infarct dementias.
Journal of neurology, neurosurgery, and psychiatry 1982;45(2):113-9.
1982: Mann D M; Yates P O
Accumulation of lipoprotein pigments in nerve cells of British and Sri Lankan nationals.
Mechanisms of ageing and development 1982;18(2):151-8.
1982: Mann D M; Davies J S; Hawkes J; Yates P O
Immunohistochemical staining of senile plaques.
Neuropathology and applied neurobiology 1982;8(1):55-61.
1981: Mann D M; Yates P O
The relationship between formation of senile plaques and neurofibrillary tangles and changes in nerve cell metabolism in Alzheimer type dementia.
Mechanisms of ageing and development 1981;17(4):395-401.
1981: Murakami T; Mastaglia F L; Mann D M; Bradley W G
Abnormal RNA metabolism in spinal motor neurons in the wobbler mouse.
Muscle & nerve 1981;4(5):407-12.
1981: Mann D M; Yates P O; Davies J S; Hawkes J
Viruses, Parkinsonism and Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1981;44(7):651.
1981: Mann D M; Yates P O
Levodopa: long-term impact on Parkinson's disease.
British medical journal (Clinical research ed.) 1981;282(6268):985-6.
1981: Scholtz C L; Swettenham K; Brown A; Mann D M
A histoquantitative study of the striate cortex and lateral geniculate body in normal, blind and demented subjects.
Neuropathology and applied neurobiology 1981;7(2):103-14.
1981: Mann D M; Yates P O
Dementia and cerebral noradrenergic innervation.
British medical journal (Clinical research ed.) 1981;282(6262):474-5.
1981: Mann D M; Neary D; Yates P O; Lincoln J; Snowden J S; Stanworth P
Alterations in protein synthetic capability of nerve cells in Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1981;44(2):97-102.
1981: Mann D M; Yates P O; Bansal D V; Marshall D J
Hypothalamus and dementia.
Lancet 1981;1(8216):393-4.
1981: Mann D M; Neary D; Yates P O; Lincoln J; Snowden J S; Stanworth P
Neurofibrillary pathology and protein synthetic capability in nerve cells in Alzheimer's disease.
Neuropathology and applied neurobiology 1981;7(1):37-47.
1980: Mann D M; Lincoln J; Yates P O; Brennan C M
Monoamine metabolism in Down syndrome.
Lancet 1980;2(8208-8209):1366-7.
1980: Toper S; Bannister C M; Lincoln J; Mann D M; Yates P O
Nuclear inclusions in Alzheimer's disease.
Neuropathology and applied neurobiology 1980;6(4):245-53.
1980: Mann D M; Lincoln J; Yates P O; Stamp J E; Toper S
Changes in the monoamine containing neurones of the human CNS in senile dementia.
The British journal of psychiatry : the journal of mental science 1980;136():533-41.
1980: Mann D M; Stamp J E; Yates P O; Bannister C M
The fine structure of the axonal torpedo in Purkinje cells of the human cerebellum.
Neurological research 1980;1(4):369-78.
1979: Mann D M; Yates P O
The effects of ageing on the pigmented nerve cells of the human locus caeruleous and substantia nigra.
Acta neuropathologica 1979;47(2):93-7.
1979: Mann D M; Yates P O
A quantitative study of the glia of the Purkinje cell layer of the cerebellum in mammals.
Neuropathology and applied neurobiology 1979;5(1):71-6.
1978: Mann D M; Yates P O; Barton C M
The DNA content of Purkinje cells in mammals.
The Journal of comparative neurology 1978;180(2):345-7.
1978: Mann D M; Yates P O; Stamp J E
The relationship between lipofuscin pigment and ageing in the human nervous system.
Journal of the neurological sciences 1978;37(1-2):83-93.
1978: Mann D M
Granulovacuolar degeneration in pyramidal cells of the hippocampus.
Acta neuropathologica 1978;42(2):149-51.
1978: Mann D M; Sinclair K G
The quantitative assessment of lipofuscin pigment, cytoplasmic RNA and nucleolar volume in senile dementia.
Neuropathology and applied neurobiology 1978;4(2):129-35.
1978: Mann D M; Barton C M; Davies J S
Post-mortem changes in human central nervous tissue and the effects on quantitation of nucleic acids and enzymes.
The Histochemical journal 1978;10(2):127-35.
1977: Mann D M; Yates P O; Barton C M
Cytophotometric mapping of neuronal changes in senile dementia.
Journal of neurology, neurosurgery, and psychiatry 1977;40(3):299-302.
1977: Mann D M; Yates P O; Barton C M
Neuromelanin and RNA in cells of substantia nigra.
Journal of neuropathology and experimental neurology 1977;36(2):379-83.
1977: Mann D M; Yates P O; Barton C M
Variations in melanin content with age in the human substantia nigra.
Biochemistry and experimental biology 1977;13(2):137-9.
1974: Mann D M; Yates P O
Lipoprotein pigments--their relationship to ageing in the human nervous system. II. The melanin content of pigmented nerve cells.
Brain : a journal of neurology 1974;97(3):489-98.
1974: Mann D M; Yates P O
Lipoprotein pigments--their relationship to ageing in the human nervous system. I. The lipofuscin content of nerve cells.
Brain : a journal of neurology 1974;97(3):481-8.
1973: Timperley W R; Mann D M; Neary D; Davies S
Creutzfeldt-Jakob disease: a histochemical study with microdensitometric assay of some enzymes.
Acta neuropathologica 1973;26(3):207-15.
1973: Yates P O; Mann D M
Polyploidy in the human nervous system.
The Journal of pathology 1973;110(3):Pvii.
1973: Mann D M; Yates P O
Polyploidy in the human nervous system. 2. Studies of the glial cell populations of the Purkinje cell layer of the human cerebellum.
Journal of the neurological sciences 1973;18(2):197-205.
1973: Mann D M; Yates P O
Polyploidy in the human nervous system. 1. The DNA content of neurones and glia of the cerebellum.
Journal of the neurological sciences 1973;18(2):183-96.

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