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Giovanni Mann

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Sarah J Chapple; Richard C M Siow; Giovanni E Mann
Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging.
Cristiane Matsuura; Julia B Barbosa; Tatiana M C Brunini; Giovanni E Mann; Thalyta L Moraes; Monique Moss; Miguel Lemos Neto; Mariana A S Siqueira; Antônio C Mendes-Ribeiro
Nitric oxide activity in platelets of dengue haemorrhagic fever patients: the apparent paradoxical role of ADMA and l-NMMA.
Christopher Torrens; Kimberley D Bruce; Christopher D Byrne; Felino R A Cagampang; Priya Ethirajan; Mark A Hanson; Giovanni E Mann; Richard C M Siow; Geraldine F Clough
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice.

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All Publications

2012: Sarah J Chapple; Richard C M Siow; Giovanni E Mann
Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging.
The international journal of biochemistry & cell biology 2012;44(8):1315-20.
2012: Cristiane Matsuura; Julia B Barbosa; Tatiana M C Brunini; Giovanni E Mann; Thalyta L Moraes; Monique Moss; Miguel Lemos Neto; Mariana A S Siqueira; Antônio C Mendes-Ribeiro
Nitric oxide activity in platelets of dengue haemorrhagic fever patients: the apparent paradoxical role of ADMA and l-NMMA.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2012;106(3):174-9.
2012: Christopher Torrens; Kimberley D Bruce; Christopher D Byrne; Felino R A Cagampang; Priya Ethirajan; Mark A Hanson; Giovanni E Mann; Richard C M Siow; Geraldine F Clough
Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice.
PloS one 2012;7(12):e50671.
2011: Alessio Alfieri; Paul A Fraser; Michel Modo; Richard C M Siow; Salil Srivastava; Giovanni E Mann
Targeting the Nrf2-Keap1 antioxidant defence pathway for neurovascular protection in stroke.
The Journal of physiology 2011;589(Pt 17):4125-36.
2011: Alison C Brewer; Thomas V A Murray; Matthew Arno; Min Zhang; Narayana P Anilkumar; Giovanni E Mann; Ajay M Shah
Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.
Free radical biology & medicine 2011;51(1):205-15.
2011: Lopa Leach; Giovanni E Mann
Consequences of fetal programming for cardiovascular disease in adulthood.
Microcirculation (New York, N.Y. : 1994) 2011;18(4):253-5.
2011: Barbara Bonacasa; Richard C M Siow; Giovanni E Mann
Impact of dietary soy isoflavones in pregnancy on fetal programming of endothelial function in offspring.
Microcirculation (New York, N.Y. : 1994) 2011;18(4):270-85.
2011: David J Rowlands; Sarah Chapple; Richard C M Siow; Giovanni E Mann
Equol-stimulated mitochondrial reactive oxygen species activate endothelial nitric oxide synthase and redox signaling in endothelial cells: roles for F-actin and GPR30.
Hypertension 2011;57(4):833-40.
2011: M He; Richard C M Siow; D Sugden; L Gao; X Cheng; Giovanni E Mann
Induction of HO-1 and redox signaling in endothelial cells by advanced glycation end products: a role for Nrf2 in vascular protection in diabetes.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2011;21(4):277-85.
2011: Xinghua Cheng; Richard C M Siow; Giovanni E Mann
Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway.
Antioxidants & redox signaling 2011;14(3):469-87.
2010: Carmen R L Assumpção; Tatiana M C Brunini; Natália R Pereira; Amélio F Godoy-Matos; Mariana A S Siqueira; Giovanni E Mann; Antônio C Mendes-Ribeiro
Insulin resistance in obesity and metabolic syndrome: is there a connection with platelet l-arginine transport?
Blood cells, molecules & diseases 2010;45(4):338-42.
2010: Richard C M Siow; Giovanni E Mann
Dietary isoflavones and vascular protection: activation of cellular antioxidant defenses by SERMs or hormesis?
Molecular aspects of medicine 2010;31(6):468-77.
2010: Rika Sugimoto; Eiji Warabi; Satoru Katayanagi; Satoshi Sakai; Junya Uwayama; Toru Yanagawa; Ayaka Watanabe; Harumi Harada; Kiyoshi Kitamura; Noriko Noguchi; Hiroshi Yoshida; Richard C M Siow; Giovanni E Mann; Tetsuro Ishii
Enhanced neointimal hyperplasia and carotid artery remodelling in sequestosome 1 deficient mice.
Journal of cellular and molecular medicine 2010;14(6B):1546-54.
2010: Natália Rodrigues Pereira; Monique Bandeira Moss; Carmen Regina Assumpção; Cláudia B Cardoso; Giovanni E Mann; Tatiana M C Brunini; Antônio C Mendes-Ribeiro
Oxidative stress, l-arginine-nitric oxide and arginase pathways in platelets from adolescents with anorexia nervosa.
Blood cells, molecules & diseases 2010;44(3):164-8.
2010: Monique Moss; Mariana A S Siqueira; Giovanni E Mann; Tatiana M C Brunini; Antônio C Mendes-Ribeiro
Platelet aggregation in arterial hypertension: is there a nitric oxide-urea connection?
Clinical and experimental pharmacology & physiology 2010;37(2):167-72.
2009: Adrian T Churchman; Anila A Anwar; Francois Y L Li; Hideyo Sato; Tetsuro Ishii; Giovanni E Mann; Richard C M Siow
Transforming growth factor-beta1 elicits Nrf2-mediated antioxidant responses in aortic smooth muscle cells.
Journal of cellular and molecular medicine 2009;13(8B):2282-92.
2009: Joern Steinert; Amanda Wyatt; Ron Jacob; Giovanni E Mann
Redox modulation of Ca2+ signaling in human endothelial and smooth muscle cells in pre-eclampsia.
Antioxidants & redox signaling 2009;11(5):1149-63.
2009: Ling Gao; Giovanni E Mann
Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling.
Cardiovascular research 2009;82(1):9-20.
2009: Giovanni E Mann; Barbara Bonacasa; Tetsuro Ishii; Richard C M Siow
Targeting the redox sensitive Nrf2-Keap1 defense pathway in cardiovascular disease: protection afforded by dietary isoflavones.
Current opinion in pharmacology 2009;9(2):139-45.
2009: Antônio C Mendes-Ribeiro; Giovanni E Mann; L R de Meirelles; M B Moss; C Matsuura; Tatiana M C Brunini
The role of exercise on L-arginine nitric oxide pathway in chronic heart failure.
The open biochemistry journal 2009;3():55-65.
2008: Joanne L Rodford; Christopher Torrens; Richard C M Siow; Giovanni E Mann; Mark A Hanson; Geraldine F Clough
Endothelial dysfunction and reduced antioxidant protection in an animal model of the developmental origins of cardiovascular disease.
The Journal of physiology 2008;586(Pt 19):4709-20.
2007: Luisa R de Meirelles; Antônio C Mendes-Ribeiro; Marcelle M Santoro; Michely A P Mendes; Michele N S B da Silva; Giovanni E Mann; Tatiana M C Brunini
Inhibitory effects of endogenous L-arginine analogues on nitric oxide synthesis in platelets: role in platelet hyperaggregability in hypertension.
Clinical and experimental pharmacology & physiology 2007;34(12):1267-71.
2007: Giovanni E Mann; David J Rowlands; Francois Y L Li; Patricia de Winter; Richard C M Siow
Activation of endothelial nitric oxide synthase by dietary isoflavones: role of NO in Nrf2-mediated antioxidant gene expression.
Cardiovascular research 2007;75(2):261-74.
2007: Iram Afzal-Ahmed; Giovanni E Mann; Andrew H Shennan; Lucilla Poston; Richard Naftalin
Preeclampsia inactivates glucose-6-phosphate dehydrogenase and impairs the redox status of erythrocytes and fetal endothelial cells.
Free radical biology & medicine 2007;42(12):1781-90.
2007: Giovanni E Mann; Jörg Niehueser-Saran; Alan Watson; Ling Gao; Tetsuro Ishii; Patricia de Winter; Richard C M Siow
Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia.
Sheng li xue bao : [Acta physiologica Sinica] 2007;59(2):117-27.
2007: Richard C M Siow; Francois Y L Li; David J Rowlands; Patricia de Winter; Giovanni E Mann
Cardiovascular targets for estrogens and phytoestrogens: transcriptional regulation of nitric oxide synthase and antioxidant defense genes.
Free radical biology & medicine 2007;42(7):909-25.
2007: Sara V Duggan; Tamsin Lindstrom; Teresa Iglesias; Phillip R Bennett; Giovanni E Mann; Simon R Bartlett
Role of atypical protein kinase C isozymes and NF-kappaB in IL-1beta-induced expression of cyclooxygenase-2 in human myometrial smooth muscle cells.
Journal of cellular physiology 2007;210(3):637-43.
2007: Tatiana M C Brunini; Antônio C Mendes-Ribeiro; J Clive Ellory; Giovanni E Mann
Platelet nitric oxide synthesis in uremia and malnutrition: a role for L-arginine supplementation in vascular protection?
Cardiovascular research 2007;73(2):359-67.
2007: Mariana Alves de Sá Siqueira; Marcela Anjos Martins; Natália Rodrigues Pereira; Monique Bandeira Moss; Sergio Santos; Giovanni E Mann; Antônio C Mendes-Ribeiro; Tatiana M C Brunini
Modulation of the cationic amino acid transport system y+L by surface potential, ouabain and thrombin in human platelets: effects of uremia.
Nephron. Experimental nephrology 2007;107(4):e132-8.
2007: Richard C M Siow; Tetsuro Ishii; Giovanni E Mann
Modulation of antioxidant gene expression by 4-hydroxynonenal: atheroprotective role of the Nrf2/ARE transcription pathway.
Redox report : communications in free radical research 2007;12(1):11-5.
2006: Neil Ashman; Tatiana M C Brunini; Giovanni E Mann; Antônio C Mendes-Ribeiro; Muhammad M Yaqoob
Increased L-arginine transport via system b0,+ in human proximal tubular cells exposed to albumin.
Clinical science (London, England : 1979) 2006;111(6):389-99.
2006: Lindsay R Queen; Yong Ji; Biao Xu; Lora Young; Kang Yao; Amanda Wyatt; David J Rowlands; Richard C M Siow; Giovanni E Mann; Albert Ferro
Mechanisms underlying beta2-adrenoceptor-mediated nitric oxide generation by human umbilical vein endothelial cells.
The Journal of physiology 2006;576(Pt 2):585-94.
2006: Patrícia F Reis; Clarissa Demézio da Silva; Tatiana M C Brunini; Monique Moss; Mariana A S Siqueira; Sergio Santos; Norman B Roberts; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Plasma amino acid profile and L-arginine uptake in red blood cells from malnourished uremic patients.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 2006;16(4):325-31.
2006: Consuelo Borrás; Juan Gambini; Mari-Carmen Gómez-Cabrera; Juan Sastre; Federico V Pallardó; Giovanni E Mann; José Viña
Genistein, a soy isoflavone, up-regulates expression of antioxidant genes: involvement of estrogen receptors, ERK1/2, and NFkappaB.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(12):2136-8.
2006: Sheeja Joy; Richard C M Siow; David J Rowlands; Marko Becker; Amanda Wyatt; Philip I Aaronson; Clive W Coen; Imre Kallo; Ron Jacob; Giovanni E Mann
The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.
The Journal of biological chemistry 2006;281(37):27335-45.
2006: Greg A Knock; Katharina Mahn; Giovanni E Mann; Jeremy P T Ward; Philip I Aaronson
Dietary soy modulates endothelium-dependent relaxation in aged male rats: Increased agonist-induced endothelium-derived hyperpolarising factor and basal nitric oxide activity.
Free radical biology & medicine 2006;41(5):731-9.
2006: Tatiana M C Brunini; Muhammad M Yaqoob; Norman B Roberts; J Clive Ellory; Monique Moss; Mariana A S Siqueira; Giovanni E Mann; Antônio C Mendes-Ribeiro
Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx.
Clinical and experimental pharmacology & physiology 2006;33(8):702-7.
2006: Tatiana M C Brunini; Norman B Roberts; Muhammad M Yaqoob; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Activation of L-arginine transport in undialysed chronic renal failure and continuous ambulatory peritoneal dialysis patients.
Clinical and experimental pharmacology & physiology 2006;33(1-2):114-8.
2005: Clarissa Demézio da Silva; Tatiana M C Brunini; Patrícia F Reis; Monique Moss; Sergio Santos; Norman B Roberts; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Effects of nutritional status on the L-arginine-nitric oxide pathway in platelets from hemodialysis patients.
Kidney international 2005;68(5):2173-9.
2005: Katharina Mahn; Consuelo Borrás; Greg A Knock; Paul Taylor; Imran Y Khan; David Sugden; Lucilla Poston; Jeremy P T Ward; Richard M Sharpe; José Viña; Philip I Aaronson; Giovanni E Mann
Dietary soy isoflavone induced increases in antioxidant and eNOS gene expression lead to improved endothelial function and reduced blood pressure in vivo.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1755-7.
2005: Anila A Anwar; Francois Y L Li; David S Leake; Tetsuro Ishii; Giovanni E Mann; Richard C M Siow
Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2.
Free radical biology & medicine 2005;39(2):227-36.
2005: Consuelo Borrás; Juan Gambini; Mari-Carmen Gómez-Cabrera; Juan Sastre; Federico V Pallardó; Giovanni E Mann; José Viña
17beta-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2[MAPK]/NFkappaB cascade.
Aging cell 2005;4(3):113-8.
2004: Bahaedin M Ben-Mahmud; Giovanni E Mann; Alessandro Datti; Antonio Orlacchio; Eva M Kohner; Rakesh Chibber
Tumor necrosis factor-alpha in diabetic plasma increases the activity of core 2 GlcNAc-T and adherence of human leukocytes to retinal endothelial cells: significance of core 2 GlcNAc-T in diabetic retinopathy.
Diabetes 2004;53(11):2968-76.
2004: Monique Moss; Tatiana M C Brunini; Roberto Soares de Moura; Lúcia E Novaes Malagris; Norman B Roberts; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Diminished L-arginine bioavailability in hypertension.
Clinical science (London, England : 1979) 2004;107(4):391-7.
2004: Tetsuro Ishii; Ken Itoh; Emilio Ruiz; David S Leake; Hiroyuki Unoki; Masayuki Yamamoto; Giovanni E Mann
Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages: activation by oxidatively modified LDL and 4-hydroxynonenal.
Circulation research 2004;94(5):609-16.
2004: Amanda Wyatt; Joern Steinert; Giovanni E Mann
Modulation of the L-arginine/nitric oxide signalling pathway in vascular endothelial cells.
Biochemical Society symposium 2004;(71):143-56.
2003: Samantha M Wileman; Giovanni E Mann; Jeremy Pearson; Anwar R Baydoun
Role of L-citrulline transport in nitric oxide synthesis in rat aortic smooth muscle cells activated with LPS and interferon-gamma.
British journal of pharmacology 2003;140(1):179-85.
2003: Rakesh Chibber; Bahaedin M Ben-Mahmud; Giovanni E Mann; Jin J Zhang; Eva M Kohner
Protein kinase C beta2-dependent phosphorylation of core 2 GlcNAc-T promotes leukocyte-endothelial cell adhesion: a mechanism underlying capillary occlusion in diabetic retinopathy.
Diabetes 2003;52(6):1519-27.
2003: Tatiana M C Brunini; Muhammad M Yaqoob; L E Novaes Malagris; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Increased nitric oxide synthesis in uraemic platelets is dependent on L-arginine transport via system y(+)L.
Pflügers Archiv : European journal of physiology 2003;445(5):547-50.
2003: Joern Steinert; Lucilla Poston; Giovanni E Mann; Ron Jacob
Abnormalities in intracellular Ca2+ regulation in fetal vascular smooth muscle in pre-eclampsia: enhanced sensitivity to arachidonic acid.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):307-9.
2003: Giovanni E Mann; David L Yudilevich; Luis Sobrevia
Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells.
Physiological reviews 2003;83(1):183-252.
2003: Emilio Ruiz; Richard C M Siow; Simon R Bartlett; Andrew M Jenner; Hideyo Sato; Shiro Bannai; Giovanni E Mann
Vitamin C inhibits diethylmaleate-induced L-cystine transport in human vascular smooth muscle cells.
Free radical biology & medicine 2003;34(1):103-10.
2002: Tatiana M C Brunini; Norman B Roberts; Muhammad M Yaqoob; Patrícia F Reis; J Clive Ellory; Giovanni E Mann; Antônio C Mendes-Ribeiro
Activation of L-arginine transport in peripheral blood mononuclear cells in chronic renal failure.
Pflügers Archiv : European journal of physiology 2002;445(1):147-51.
2002: Amanda Wyatt; Joern Steinert; Caroline P D Wheeler-Jones; Anthony J Morgan; David Sugden; Jeremy Pearson; Luis Sobrevia; Giovanni E Mann
Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(12):1584-94.
2002: Joern Steinert; Amanda Wyatt; Lucilla Poston; Ron Jacob; Giovanni E Mann
Preeclampsia is associated with altered Ca2+ regulation and NO production in human fetal venous endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):721-3.
2002: Andrew M Jenner; J Emilio Ruiz; Christina Dunster; Barry Halliwell; Giovanni E Mann; Richard C M Siow
Vitamin C protects against hypochlorous Acid-induced glutathione depletion and DNA base and protein damage in human vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(4):574-80.
2001: Claudio Aguayo; Carlos Flores; Jorge Parodi; R Rojas; Giovanni E Mann; Jeremy Pearson; Luis Sobrevia
Modulation of adenosine transport by insulin in human umbilical artery smooth muscle cells from normal or gestational diabetic pregnancies.
The Journal of physiology 2001;534(Pt 1):243-54.
2001: Hideyo Sato; Kazumi Kuriyama-Matsumura; T Hashimoto; H Sasaki; Hongyu Wang; T Ishii; Giovanni E Mann; Shiro Bannai
Effect of oxygen on induction of the cystine transporter by bacterial lipopolysaccharide in mouse peritoneal macrophages.
The Journal of biological chemistry 2001;276(13):10407-12.
2001: Antônio C Mendes-Ribeiro; Tatiana M C Brunini; J Clive Ellory; Giovanni E Mann
Abnormalities in L-arginine transport and nitric oxide biosynthesis in chronic renal and heart failure.
Cardiovascular research 2001;49(4):697-712.
2000: Viviana Montecinos; Claudio Aguayo; Carlos Flores; Amanda Wyatt; Jeremy Pearson; Giovanni E Mann; Luis Sobrevia
Regulation of adenosine transport by D-glucose in human fetal endothelial cells: involvement of nitric oxide, protein kinase C and mitogen-activated protein kinase.
The Journal of physiology 2000;529 Pt 3():777-90.
2000: DO Ruehlmann; Giovanni E Mann
Rapid non-genomic vasodilator actions of oestrogens and sex steroids.
Current medicinal chemistry 2000;7(5):533-41.
2000: RD Rakhit; Richard J Edwards; JW Mockridge; Anwar R Baydoun; Amanda Wyatt; Giovanni E Mann; Michael S Marber
Nitric oxide-induced cardioprotection in cultured rat ventricular myocytes.
American journal of physiology. Heart and circulatory physiology 2000;278(4):H1211-7.
1999: Simon R Bartlett; Phillip R Bennett; JS Campa; William Dennes; Donna M Slater; Giovanni E Mann; Lucilla Poston; R Poston
Expression of nitric oxide synthase isoforms in pregnant human myometrium.
The Journal of physiology 1999;521 Pt 3():705-16.
1999: Anwar R Baydoun; S M Wileman; Caroline P D Wheeler-Jones; Michael S Marber; Giovanni E Mann; Jeremy Pearson; E I Closs
Transmembrane signalling mechanisms regulating expression of cationic amino acid transporters and inducible nitric oxide synthase in rat vascular smooth muscle cells.
The Biochemical journal 1999;344 Pt 1():265-72.
1999: Simon R Bartlett; R Sawdy; Giovanni E Mann
Induction of cyclooxygenase-2 expression in human myometrial smooth muscle cells by interleukin-1beta: involvement of p38 mitogen-activated protein kinase.
The Journal of physiology 1999;520 Pt 2():399-406.
1999: Richard C M Siow; J P Richards; K C Pedley; DS Leake; Giovanni E Mann
Vitamin C protects human vascular smooth muscle cells against apoptosis induced by moderately oxidized LDL containing high levels of lipid hydroperoxides.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(10):2387-94.
1999: Richard C M Siow; H Sato; DS Leake; T Ishii; Shiro Bannai; Giovanni E Mann
Induction of antioxidant stress proteins in vascular endothelial and smooth muscle cells: protective action of vitamin C against atherogenic lipoproteins.
Free radical research 1999;31(4):309-18.
1999: Antônio C Mendes-Ribeiro; Tatiana M C Brunini; M Yaqoob; J K Aronson; Giovanni E Mann; J Clive Ellory
Identification of system y+L as the high-affinity transporter for L-arginine in human platelets: up-regulation of L-arginine influx in uraemia.
Pflügers Archiv : European journal of physiology 1999;438(4):573-5.
1999: J H Sweiry; I Shibuya; N Asada; K Niwa; K Doolabh; Y Habara; T Kanno; Giovanni E Mann
Acute oxidative stress modulates secretion and repetitive Ca2+ spiking in rat exocrine pancreas.
Biochimica et biophysica acta 1999;1454(1):19-30.
1999: Richard C M Siow; H Sato; Giovanni E Mann
Heme oxygenase-carbon monoxide signalling pathway in atherosclerosis: anti-atherogenic actions of bilirubin and carbon monoxide?
Cardiovascular research 1999;41(2):385-94.
1998: Hideyo Sato; Kazumi Kuriyama-Matsumura; Richard C M Siow; T Ishii; Shiro Bannai; Giovanni E Mann
Induction of cystine transport via system x-c and maintenance of intracellular glutathione levels in pancreatic acinar and islet cell lines.
Biochimica et biophysica acta 1998;1414(1-2):85-94.
1998: Richard C M Siow; H Sato; DS Leake; Jeremy Pearson; Shiro Bannai; Giovanni E Mann
Vitamin C protects human arterial smooth muscle cells against atherogenic lipoproteins: effects of antioxidant vitamins C and E on oxidized LDL-induced adaptive increases in cystine transport and glutathione.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(10):1662-70.
1998: DO Ruehlmann; Joern Steinert; M A Valverde; Ron Jacob; Giovanni E Mann
Environmental estrogenic pollutants induce acute vascular relaxation by inhibiting L-type Ca2+ channels in smooth muscle cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(7):613-9.
1998: T R Cannon; Giovanni E Mann; A R Baydoun
Mechanisms of acute vasodilator response to bacterial lipopolysaccharide in the rat coronary microcirculation.
British journal of pharmacology 1998;123(4):637-44.
1998: H Hanssen; Tatiana M C Brunini; Michael Conway; A P Banning; Norman B Roberts; Giovanni E Mann; J Clive Ellory; Antônio C Mendes-Ribeiro
Increased L-arginine transport in human erythrocytes in chronic heart failure.
Clinical science (London, England : 1979) 1998;94(1):43-8.
1998: Luis Sobrevia; David L Yudilevich; Giovanni E Mann
Elevated D-glucose induces insulin insensitivity in human umbilical endothelial cells isolated from gestational diabetic pregnancies.
The Journal of physiology 1998;506 ( Pt 1)():219-30.
1997: Antônio C Mendes-Ribeiro; H Hanssen; K Kiessling; Norman B Roberts; Giovanni E Mann; J Clive Ellory
Transport of L-arginine and the nitric oxide inhibitor NG-monomethyl-L-arginine in human erythrocytes in chronic renal failure.
Clinical science (London, England : 1979) 1997;93(1):57-64.
1997: Luis Sobrevia; Giovanni E Mann
Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia.
Experimental physiology 1997;82(3):423-52.
1997: H Sato; Richard C M Siow; S Bartlett; S Taketani; T Ishii; Shiro Bannai; Giovanni E Mann
Expression of stress proteins heme oxygenase-1 and -2 in acute pancreatitis and pancreatic islet betaTC3 and acinar AR42J cells.
FEBS letters 1997;405(2):219-23.
1997: M T Jay; S Chirico; Richard C M Siow; K Richard Bruckdorfer; M Jacobs; DS Leake; Jeremy Pearson; Giovanni E Mann
Modulation of vascular tone by low density lipoproteins: effects on L-arginine transport and nitric oxide synthesis.
Experimental physiology 1997;82(2):349-60.
1997: Luis Sobrevia; David L Yudilevich; Giovanni E Mann
Activation of A2-purinoceptors by adenosine stimulates L-arginine transport (system y+) and nitric oxide synthesis in human fetal endothelial cells.
The Journal of physiology 1997;499 ( Pt 1)():135-40.
1997: DO Ruehlmann; T R Cannon; Ron Jacob; Giovanni E Mann
Differential effects of steroids on vascular tone and smooth muscle cell Ca(2+)-homeostasis.
Biochemical Society transactions 1997;25(1):112S.
1997: DO Ruehlmann; Giovanni E Mann
Actions of oestrogen on vascular endothelial and smooth-muscle cells.
Biochemical Society transactions 1997;25(1):40-5.
1997: R Contreras; O Fuentes; Giovanni E Mann; Luis Sobrevia
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
The Journal of physiology 1997;498 ( Pt 3)():787-96.
1996: Luis Sobrevia; Angel Nadal; D L Yudilevich; Giovanni E Mann
Activation of L-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells.
The Journal of physiology 1996;490 ( Pt 3)():775-81.
1996: J H Sweiry; Giovanni E Mann
Role of oxidative stress in the pathogenesis of acute pancreatitis.
Scandinavian journal of gastroenterology. Supplement 1996;219():10-5.
1996: R G Bogle; A R Baydoun; Jeremy Pearson; Giovanni E Mann
Regulation of L-arginine transport and nitric oxide release in superfused porcine aortic endothelial cells.
The Journal of physiology 1996;490 ( Pt 1)():229-41.
1995: S M Wileman; Giovanni E Mann; A R Baydoun
Induction of L-arginine transport and nitric oxide synthase in vascular smooth muscle cells: synergistic actions of pro-inflammatory cytokines and bacterial lipopolysaccharide.
British journal of pharmacology 1995;116(8):3243-50.
1995: Luis Sobrevia; P Cesare; D L Yudilevich; Giovanni E Mann
Diabetes-induced activation of system y+ and nitric oxide synthase in human endothelial cells: association with membrane hyperpolarization.
The Journal of physiology 1995;489 ( Pt 1)():183-92.
1995: M Muñoz; J H Sweiry; Giovanni E Mann
Insulin stimulates cationic amino acid transport activity in the isolated perfused rat pancreas.
Experimental physiology 1995;80(5):745-53.
1995: Richard C M Siow; T Ishii; Hideyo Sato; S Taketani; DS Leake; J H Sweiry; Jeremy Pearson; Shiro Bannai; Giovanni E Mann
Induction of the antioxidant stress proteins heme oxygenase-1 and MSP23 by stress agents and oxidised LDL in cultured vascular smooth muscle cells.
FEBS letters 1995;368(2):239-42.
1995: J H Sweiry; J Sastre; J Viña; H P Elsässer; Giovanni E Mann
A role for gamma-glutamyl transpeptidase and the amino acid transport system xc- in cystine transport by a human pancreatic duct cell line.
The Journal of physiology 1995;485 ( Pt 1)():167-77.
1994: A R Baydoun; R G Bogle; Jeremy Pearson; Giovanni E Mann
Discrimination between citrulline and arginine transport in activated murine macrophages: inefficient synthesis of NO from recycling of citrulline to arginine.
British journal of pharmacology 1994;112(2):487-92.
1994: A R Baydoun; Giovanni E Mann
Selective targeting of nitric oxide synthase inhibitors to system y+ in activated macrophages.
Biochemical and biophysical research communications 1994;200(2):726-31.
1994: R G Bogle; Giovanni E Mann; Jeremy Pearson; D M Morgan
Endothelial polyamine uptake: selective stimulation by L-arginine deprivation or polyamine depletion.
The American journal of physiology 1994;266(3 Pt 1):C776-83.
1993: A R Baydoun; R G Bogle; Jeremy Pearson; Giovanni E Mann
Selective inhibition by dexamethasone of induction of NO synthase, but not of induction of L-arginine transport, in activated murine macrophage J774 cells.
British journal of pharmacology 1993;110(4):1401-6.
1993: A R Baydoun; R D Foale; Giovanni E Mann
Bacterial endotoxin rapidly stimulates prolonged endothelium-dependent vasodilatation in the rat isolated perfused heart.
British journal of pharmacology 1993;109(4):987-91.
1993: A R Baydoun; R G Bogle; Jeremy Pearson; Giovanni E Mann
Arginine uptake and metabolism in cultured murine macrophages.
Agents and actions 1993;38 Spec No():C127-9.
1992: R G Bogle; A R Baydoun; Jeremy Pearson; S Moncada; Giovanni E Mann
L-arginine transport is increased in macrophages generating nitric oxide.
The Biochemical journal 1992;284 ( Pt 1)():15-8.
1992: R G Bogle; S Moncada; Jeremy Pearson; Giovanni E Mann
Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell L-arginine transporter.
British journal of pharmacology 1992;105(4):768-70.
1991: J H Sweiry; P W Emery; M Muñoz; K Doolabh; Giovanni E Mann
Influx and incorporation into protein of L-phenylalanine in the perfused rat pancreas: effects of amino acid deprivation and carbachol.
Biochimica et biophysica acta 1991;1070(1):135-42.
1991: J H Sweiry; Giovanni E Mann
Pancreatic microvascular permeability in caerulein-induced acute pancreatitis.
The American journal of physiology 1991;261(4 Pt 1):G685-92.
1991: J H Sweiry; M Muñoz; Giovanni E Mann
Cis-inhibition and trans-stimulation of cationic amino acid transport in the perfused rat pancreas.
The American journal of physiology 1991;261(3 Pt 1):C506-14.
1991: J Sastre; J H Sweiry; K Doolabh; J Viña; Giovanni E Mann
Significance of gamma-glutamyltranspeptidase in exocrine pancreatic amino acid transport.
Biochimica et biophysica acta 1991;1065(2):213-6.
1990: A R Baydoun; P W Emery; J D Pearson; Giovanni E Mann
Substrate-dependent regulation of intracellular amino acid concentrations in cultured bovine aortic endothelial cells.
Biochemical and biophysical research communications 1990;173(3):940-8.
1990: R G Bogle; D M Morgan; Jeremy Pearson; Giovanni E Mann
Transport of polyamines in perfused porcine aortic endothelial cell microcarrier cultures.
Biochemical Society transactions 1990;18(6):1222-3.
1989: Giovanni E Mann; P S Norman; I C Smith
Amino acid efflux in the isolated perfused rat pancreas: trans-stimulation by extracellular amino acids.
The Journal of physiology 1989;416():485-502.
1989: P S Norman; Y Habara; Giovanni E Mann
Paradoxical effects of endogenous and exogenous insulin on amino acid transport activity in the isolated rat pancreas: somatostatin-14 inhibits insulin action.
Diabetologia 1989;32(3):177-84.
1989: Giovanni E Mann; M Muñoz
Adaptation of pancreatic amino acid transport in rats after treatment with the synthetic protease inhibitor camostat mesilate.
Pancreas 1989;4(5):601-5.
1988: M Muñoz; P W Emery; S Peran; Giovanni E Mann
Dietary regulation of amino acid transport activity in the exocrine pancreatic epithelium.
Biochimica et biophysica acta 1988;945(2):273-80.
1988: P S Norman; Giovanni E Mann
Secretagogue-induced changes in system A amino acid transport in the rat exocrine pancreas: stimulation of 2-methylaminoisobutyric acid efflux by carbachol.
Biochimica et biophysica acta 1988;943(3):541-6.
1988: Giovanni E Mann; M Munoz; S Peran
Ethanol-induced alterations in exocrine pancreatic amino acid transport and secretion.
Alcohol (Fayetteville, N.Y.) 1988;5(5):359-65.
1988: Giovanni E Mann; S A Smith; P S Norman; P W Emery
Fasting, refeeding and diabetes modulate free amino acid concentrations in the rat exocrine pancreas: role of transstimulation in amino acid efflux.
Pancreas 1988;3(1):67-76.
1986: Giovanni E Mann; M Muñoz; S Peran
Fasting and refeeding modulate neutral amino acid transport activity in the basolateral membrane of the rat exocrine pancreatic epithelium: fasting-induced insulin insensitivity.
Biochimica et biophysica acta 1986;862(1):119-26.
1986: Giovanni E Mann; S Peran
Basolateral amino acid transport systems in the perfused exocrine pancreas: sodium-dependency and kinetic interactions between influx and efflux mechanisms.
Biochimica et biophysica acta 1986;858(2):263-74.
1986: Giovanni E Mann; Y Habara; S Peran
Characteristics of L-glutamine transport in the perfused rat exocrine pancreas: lack of sensitivity to insulin and streptozotocin-induced experimental diabetes.
Pancreas 1986;1(3):239-45.
1981: J C Bustamante; Giovanni E Mann; D L Yudilevich
Specificity of neutral amino acid uptake at the basolateral side of the epithelium in the cat salivary gland in situ.
The Journal of physiology 1981;313():65-79.