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Richard Mann
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Research Profile (preview)
Chemicals & Drugs
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Physiology
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Concepts & Ideas
Phenomena
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Network (preview)
9
Ryoo, Hyung Don
8
Chan, Siu-Kwong
7
Casares, Fernando
6
Culi, Joaquim
6
Abu-Shaar, Muna
5
Sosinsky, Alona
5
Honig, Barry
4
Wildonger, Jill
4
Affolter, Markus
4
Crickmore, Michael
4
Gebelein, Brian
4
Krumlauf, Robb
3
Hogness, David
3
Pöpperl, H
2
Morata, Ginés
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Publications
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All Publications
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2009: Rohs Remo; West Sean M; Sosinsky Alona; Liu Peng; Mann Richard S; Honig Barry
The role of DNA shape in protein-DNA recognition.
Nature 2009;461(7268):1248-53.
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2009: Peng H Wayne; Slattery Matthew; Mann Richard S
Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc.
Genes & development 2009;23(19):2307-19.
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2009: Crickmore Michael A; Ranade Vikram; Mann Richard S
Regulation of Ubx expression by epigenetic enhancer silencing in response to Ubx levels and genetic variation.
PLoS genetics 2009;5(9):e1000633.
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2009: Baek Myungin; Mann Richard S
Lineage and birth date specify motor neuron targeting and dendritic architecture in adult Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(21):6904-16.
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2009: McKay Daniel J; Estella Carlos; Mann Richard S
The origins of the Drosophila leg revealed by the cis-regulatory architecture of the Distalless gene.
Development (Cambridge, England) 2009;136(1):61-71.
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2009: Mann Richard S; Lelli Katherine M; Joshi Rohit
Hox specificity unique roles for cofactors and collaborators.
Current topics in developmental biology 2009;88():63-101.
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2008: Affolter Markus; Slattery Matthew; Mann Richard S
A lexicon for homeodomain-DNA recognition.
Cell 2008;133(7):1133-5.
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2008: Estella Carlos; Mann Richard S
Logic of Wg and Dpp induction of distal and medial fates in the Drosophila leg.
Development (Cambridge, England) 2008;135(4):627-36.
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2008: Estella Carlos; McKay Daniel J; Mann Richard S
Molecular integration of wingless, decapentaplegic, and autoregulatory inputs into Distalless during Drosophila leg development.
Developmental cell 2008;14(1):86-96.
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2007: Joshi Rohit; Passner Jonathan M; Rohs Remo; Jain Rinku; Sosinsky Alona; Crickmore Michael A; Jacob Vinitha; Aggarwal Aneel K; Honig Barry; Mann Richard S
Functional specificity of a Hox protein mediated by the recognition of minor groove structure.
Cell 2007;131(3):530-43.
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2007: Gebelein Brian; Mann Richard S
Compartmental modulation of abdominal Hox expression by engrailed and sloppy-paired patterns the fly ectoderm.
Developmental biology 2007;308(2):593-605.
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2007: Sosinsky Alona; Honig Barry; Mann Richard S; Califano Andrea
Discovering transcriptional regulatory regions in Drosophila by a nonalignment method for phylogenetic footprinting.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(15):6305-10.
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2007: Zirin Jonathan D; Mann Richard S
Nubbin and Teashirt mark barriers to clonal growth along the proximal-distal axis of the Drosophila wing.
Developmental biology 2007;304(2):745-58.
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2007: Stevens Katherine E; Mann Richard S
A balance between two nuclear localization sequences and a nuclear export sequence governs extradenticle subcellular localization.
Genetics 2007;175(4):1625-36.
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2007: Crickmore Michael A; Mann Richard S
Hox control of morphogen mobility and organ development through regulation of glypican expression.
Development (Cambridge, England) 2007;134(2):327-34.
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2006: Crickmore Michael A; Mann Richard S
Hox control of organ size by regulation of morphogen production and mobility.
Science (New York, N.Y.) 2006;313(5783):63-8.
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2006: Noro Barbara; Culi Joaquim; McKay Daniel J; Zhang Wen; Mann Richard S
Distinct functions of homeodomain-containing and homeodomain-less isoforms encoded by homothorax.
Genes & development 2006;20(12):1636-50.
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2006: Culi Joaquim; Aroca Pilar; Modolell Juan; Mann Richard S
jing is required for wing development and to establish the proximo-distal axis of the leg in Drosophila melanogaster.
Genetics 2006;173(1):255-66.
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2005: Wildonger Jill; Mann Richard S
Evidence that nervy, the Drosophila homolog of ETO/MTG8, promotes mechanosensory organ development by enhancing Notch signaling.
Developmental biology 2005;286(2):507-20.
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2005: Ice Ryan J; Wildonger Jill; Mann Richard S; Hiebert Scott W
Comment on "Nervy links protein kinase A to plexin-mediated semaphorin repulsion".
Science (New York, N.Y.) 2005;309(5734):558; author reply 558.
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2005: Wildonger Jill; Sosinsky Alona; Honig Barry; Mann Richard S
Lozenge directly activates argos and klumpfuss to regulate programmed cell death.
Genes & development 2005;19(9):1034-9.
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2005: Mann Richard S; Culi Joaquim
Developmental biology: morphogens hitch a greasy ride.
Nature 2005;435(7038):30-3.
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2005: Wildonger Jill; Mann Richard S
The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor.
Development (Cambridge, England) 2005;132(10):2263-72.
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2004: Zirin Jonathan D; Mann Richard S
Differing strategies for the establishment and maintenance of teashirt and homothorax repression in the Drosophila wing.
Development (Cambridge, England) 2004;131(22):5683-93.
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2004: Gebelein Brian; McKay Daniel J; Mann Richard S
Direct integration of Hox and segmentation gene inputs during Drosophila development.
Nature 2004;431(7009):653-9.
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2004: Bonin Christopher P; Mann Richard S
A piggyBac transposon gene trap for the analysis of gene expression and function in Drosophila.
Genetics 2004;167(4):1801-11.
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2004: Culi Joaquim; Springer Timothy A; Mann Richard S
Boca-dependent maturation of beta-propeller/EGF modules in low-density lipoprotein receptor proteins.
The EMBO journal 2004;23(6):1372-80.
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2003: Sosinsky Alona; Bonin Christopher P; Mann Richard S; Honig Barry
Target Explorer: An automated tool for the identification of new target genes for a specified set of transcription factors.
Nucleic acids research 2003;31(13):3589-92.
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2003: Wang Zhaohui; Mann Richard S
Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis.
Development (Cambridge, England) 2003;130(13):2853-65.
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2003: Culi Joaquim; Mann Richard S
Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.
Cell 2003;112(3):343-54.
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2003: Kobayashi Masatomo; Fujioka Miki; Tolkunova Elena N; Deka Deepali; Abu-Shaar Muna; Mann Richard S; Jaynes James B
Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila.
Development (Cambridge, England) 2003;130(4):741-51.
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2002: Gebelein Brian; Culi Joaquim; Ryoo Hyung Don; Zhang Wen; Mann Richard S
Specificity of Distalless repression and limb primordia development by abdominal Hox proteins.
Developmental cell 2002;3(4):487-98.
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2002: Mann Richard S; Carroll Sean B
Molecular mechanisms of selector gene function and evolution.
Current opinion in genetics & development 2002;12(5):592-600.
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2002: Bessa Jose; Gebelein Brian; Pichaud Franck; Casares Fernando; Mann Richard S
Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt.
Genes & development 2002;16(18):2415-27.
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2002: Mann Richard S; Casares Fernando
Developmental biology: signalling legacies.
Nature 2002;418(6899):737-9.
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2001: Casares F; Mann R S
The ground state of the ventral appendage in Drosophila.
Science (New York, N.Y.) 2001;293(5534):1477-80.
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2000: Casares F; Mann R S
A dual role for homothorax in inhibiting wing blade development and specifying proximal wing identities in Drosophila.
Development (Cambridge, England) 2000;127(7):1499-508.
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2000: Mann R S; Morata G
The developmental and molecular biology of genes that subdivide the body of Drosophila.
Annual review of cell and developmental biology 2000;16():243-71.
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1999: Ryoo H D; Marty T; Casares F; Affolter M; Mann R S
Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex.
Development (Cambridge, England) 1999;126(22):5137-48.
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1999: Ryoo H D; Mann R S
The control of trunk Hox specificity and activity by Extradenticle.
Genes & development 1999;13(13):1704-16.
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1999: Abu-Shaar M; Ryoo H D; Mann R S
Control of the nuclear localization of Extradenticle by competing nuclear import and export signals.
Genes & development 1999;13(8):935-45.
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1999: Passner J M; Ryoo H D; Shen L; Mann R S; Aggarwal A K
Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex.
Nature 1999;397(6721):714-9.
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1998: Abu-Shaar M; Mann R S
Generation of multiple antagonistic domains along the proximodistal axis during Drosophila leg development.
Development (Cambridge, England) 1998;125(19):3821-30.
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1998: Mann R S; Affolter M
Hox proteins meet more partners.
Current opinion in genetics & development 1998;8(4):423-9.
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1998: González-Crespo S; Abu-Shaar M; Torres M; Martínez-A C; Mann R S; Morata G
Antagonism between extradenticle function and Hedgehog signalling in the developing limb.
Nature 1998;394(6689):196-200.
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1998: Casares F; Mann R S
Control of antennal versus leg development in Drosophila.
Nature 1998;392(6677):723-6.
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1997: Grieder N C; Marty T; Ryoo H D; Mann R S; Affolter M
Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling.
The EMBO journal 1997;16(24):7402-10.
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1997: Rieckhof G E; Casares F; Ryoo H D; Abu-Shaar M; Mann R S
Nuclear translocation of extradenticle requires homothorax, which encodes an extradenticle-related homeodomain protein.
Cell 1997;91(2):171-83.
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1997: Mann R S
Why are Hox genes clustered?
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(8):661-4.
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1997: Maconochie M K; Nonchev S; Studer M; Chan S K; Pöpperl H; Sham M H; Mann R S; Krumlauf R
Cross-regulation in the mouse HoxB complex: the expression of Hoxb2 in rhombomere 4 is regulated by Hoxb1.
Genes & development 1997;11(14):1885-95.
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1997: Jaffe L; Ryoo H D; Mann R S
A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila.
Genes & development 1997;11(10):1327-40.
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1997: Chan S K; Ryoo H D; Gould A; Krumlauf R; Mann R S
Switching the in vivo specificity of a minimal Hox-responsive element.
Development (Cambridge, England) 1997;124(10):2007-14.
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1996: Mann R S; Abu-Shaar M
Nuclear import of the homeodomain protein extradenticle in response to Wg and Dpp signalling.
Nature 1996;383(6601):630-3.
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1996: Mann R S; Chan S K
Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins.
Trends in genetics : TIG 1996;12(7):258-62.
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1996: Chan S K; Pöpperl H; Krumlauf R; Mann R S
An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif.
The EMBO journal 1996;15(10):2476-87.
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1996: Chan S K; Mann R S
A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(11):5223-8.
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1995: Mann R S
The specificity of homeotic gene function.
BioEssays : news and reviews in molecular, cellular and developmental biology 1995;17(10):855-63.
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1995: Pöpperl H; Bienz M; Studer M; Chan S K; Aparicio S; Brenner S; Mann R S; Krumlauf R
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx.
Cell 1995;81(7):1031-42.
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1995: Feinstein P G; Kornfeld K; Hogness D S; Mann R S
Identification of homeotic target genes in Drosophila melanogaster including nervy, a proto-oncogene homologue.
Genetics 1995;140(2):573-86.
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1994: Mann R S
Engrailed-mediated repression of Ultrabithorax is necessary for the parasegment 6 identity in Drosophila.
Development (Cambridge, England) 1994;120(11):3205-12.
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1994: Chan S K; Jaffe L; Capovilla M; Botas J; Mann R S
The DNA binding specificity of Ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein.
Cell 1994;78(4):603-15.
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1993: Chan S K; Mann R S
The segment identity functions of Ultrabithorax are contained within its homeo domain and carboxy-terminal sequences.
Genes & development 1993;7(5):796-811.
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1993: Irvine K D; Botas J; Jha S; Mann R S; Hogness D S
Negative autoregulation by Ultrabithorax controls the level and pattern of its expression.
Development (Cambridge, England) 1993;117(1):387-99.
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1990: Mann R S; Hogness D S
Functional dissection of Ultrabithorax proteins in D. melanogaster.
Cell 1990;60(4):597-610.
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