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David Mantle

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Muhammed A Gok; Brian K Shenton; Maurice Pelsers; A Whitwood; David Mantle; Chris Cornell; Robert Peaston; David A Rix; Bryon C Jaques; Naeem Soomro; Derek M Manas; David Talbot
Ischemia-reperfusion injury in cadaveric nonheart beating, cadaveric heart beating and live donor renal transplants.
Muhammed A Gok; Brian K Shenton; Maurice Pelsers; A Whitwood; David Mantle; Chris Cornell; Robert Peaston; David A Rix; Bryon C Jaques; Naeem Soomro; Derek M Manas; David Talbot
Reperfusion injury in renal transplantation: comparison of LD, HBD and NHBD renal transplants.
Muhammed A Gok; Maurice Pelzers; Jan F C Glatz; Brian K Shenton; Pamela E Buckley; Robert Peaston; Chris Cornell; David Mantle; Naeem Soomro; Bryon C Jaques; Derek M Manas; David Talbot
Do tissue damage biomarkers used to assess machine-perfused NHBD kidneys predict long-term renal function post-transplant?

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2006: Muhammed A Gok; Brian K Shenton; Maurice Pelsers; A Whitwood; David Mantle; Chris Cornell; Robert Peaston; David A Rix; Bryon C Jaques; Naeem Soomro; Derek M Manas; David Talbot
Ischemia-reperfusion injury in cadaveric nonheart beating, cadaveric heart beating and live donor renal transplants.
The Journal of urology 2006;175(2):641-7.
2004: Muhammed A Gok; Brian K Shenton; Maurice Pelsers; A Whitwood; David Mantle; Chris Cornell; Robert Peaston; David A Rix; Bryon C Jaques; Naeem Soomro; Derek M Manas; David Talbot
Reperfusion injury in renal transplantation: comparison of LD, HBD and NHBD renal transplants.
Annals of transplantation : quarterly of the Polish Transplantation Society 2004;9(2):33-4.
2003: Muhammed A Gok; Maurice Pelzers; Jan F C Glatz; Brian K Shenton; Pamela E Buckley; Robert Peaston; Chris Cornell; David Mantle; Naeem Soomro; Bryon C Jaques; Derek M Manas; David Talbot
Do tissue damage biomarkers used to assess machine-perfused NHBD kidneys predict long-term renal function post-transplant?
Clinica chimica acta; international journal of clinical chemistry 2003;338(1-2):33-43.
2003: David Mantle; Richard Wilkins; Muhammed A Gok
Comparison of antioxidant activity in commercial Ginkgo biloba preparations.
Journal of alternative and complementary medicine (New York, N.Y.) 2003;9(5):625-9.
2003: Muhammed A Gok; Maurice Pelsers; Jan F C Glatz; Aftab A Bhatti; Brian K Shenton; Robert Peaston; Chris Cornell; David Mantle; David Talbot
Comparison of perfusate activities of glutathione S-transferase, alanine aminopeptidase and fatty acid binding protein in the assessment of non-heart-beating donor kidneys.
Annals of clinical biochemistry 2003;40(Pt 3):252-8.
2003: Rajkumar Rajendram; Jaspaul S Marway; David Mantle; Timothy J Peters; Victor R Preedy
Skeletal muscle and jejunal protein synthesis in normal and ethanol-treated rats: the effect of the nitric oxide synthase inhibitors, L-omega-nitro-L-arginine methyl ester and N(G)-nitro-L-arginine in vivo.
Metabolism: clinical and experimental 2003;52(4):397-401.
2003: Muhammed A Gok; Brian K Shenton; Pamela E Buckley; Robert Peaston; Chris Cornell; E Leung; M F A El-Sheikh; David Mantle; Naeem Soomro; BC Jacques; Derek M Manas; David Talbot; Aftab A Bhatti
Use of thrombolytic streptokinase as a preflush in the NHBD procurement.
Transplantation proceedings 2003;35(2):769-70.
2003: Muhammed A Gok; Maurice Pelsers; Jan F C Glatz; Brian K Shenton; Pamela E Buckley; Chris Cornell; Robert Peaston; E Leung; M F A El-Sheikh; David Mantle; BC Jacques; Naeem Soomro; Derek M Manas; David Talbot
Creatinine clearance and viability biomarkers of machine perfused non-heart-beating donors: is there a correlation?
Transplantation proceedings 2003;35(2):768.
2003: Victor R Preedy; Kay Ohlendieck; Junko Adachi; Michael Koll; Alan Sneddon; Ross Hunter; Rajkumar Rajendram; David Mantle; Timothy J Peters
The importance of alcohol-induced muscle disease.
Journal of muscle research and cell motility 2003;24(1):55-63.
2002: Muhammed A Gok; Brian K Shenton; Robert Peaston; Chris Cornell; H J Gicquel; D Aitchison; David Mantle; J Dark; David Talbot
Use of streptokinase in a non-heart-beating donor animal model.
Transplantation proceedings 2002;34(7):2615-6.
2002: Muhammed A Gok; Brian K Shenton; Robert Peaston; Chris Cornell; Helen Robertson; Marie Mathers; Jonathan D Aitchison; John H Dark; David Mantle; David Talbot
Improving the quality of kidneys from non-heart-beating donors, using streptokinase: an animal model.
Transplantation 2002;73(12):1869-74.
2002: Victor R Preedy; Junko Adachi; Migiwa Asano; Michael Koll; David Mantle; Onni Niemela; Seppo Parkkila; Alistair G Paice; Timothy Peters; Rajkumar Rajendram; Helmut Seitz; Yasuhiro Ueno; Simon Worrall
Free radicals in alcoholic myopathy: indices of damage and preventive studies.
Free radical biology & medicine 2002;32(8):683-7.
2002: David Mantle; Victor R Preedy
Adverse and beneficial functions of proteolytic enzymes in skeletal muscle. An overview.
Adverse drug reactions and toxicological reviews 2002;21(1-2):31-49.
2002: Michael Koll; S Ahmed; David Mantle; T M Donohue; T Norman Palmer; Ulrich A Simanowski; H K Seltz; Timothy J Peters; Victor R Preedy
Effect of acute and chronic alcohol treatment and their superimposition on lysosomal, cytoplasmic, and proteosomal protease activities in rat skeletal muscle in vivo.
Metabolism: clinical and experimental 2002;51(1):97-104.
2001: Victor R Preedy; Junko Adachi; Yasuhiro Ueno; S Ahmed; David Mantle; N Mullatti; Rajkumar Rajendram; Timothy J Peters
Alcoholic skeletal muscle myopathy: definitions, features, contribution of neuropathy, impact and diagnosis.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2001;8(6):677-87.
2001: David Mantle; S Siddique; F Eddeb; David Mendelow
Comparison of protein carbonyl and antioxidant levels in brain tissue from intracerebral haemorrhage and control cases.
Clinica chimica acta; international journal of clinical chemistry 2001;312(1-2):185-90.
2001: Victor R Preedy; Wassif S Wassif; D Baldwin; J Jones; G Falkous; Jaspaul S Marway; David Mantle; David Scott
Skeletal muscle protein loss due to D-penicillamine results from reduced protein synthesis.
The international journal of biochemistry & cell biology 2001;33(10):1013-26.
2001: Victor R Preedy; Alistair G Paice; David Mantle; A S Dhillon; T Norman Palmer; Timothy J Peters
Alcoholic myopathy: biochemical mechanisms.
Drug and alcohol dependence 2001;63(3):199-205.
2001: David Mantle; Muhammed A Gok; T W J Lennard
Adverse and beneficial effects of plant extracts on skin and skin disorders.
Adverse drug reactions and toxicological reviews 2001;20(2):89-103.
2001: Shlokarth Balupuri; David Mantle; M Mohamed; Brian K Shenton; Muhammed A Gok; Naeem Soomro; Derek M Manas; J Kirby; David Talbot
Machine perfusion and viability assessment of non-heart-beating donor kidneys-a single-centre result.
Transplantation proceedings 2001;33(1-2):1119-20.
2000: Matthew Eliot Reilly; David Mantle; J Salisbury; Timothy J Peters; Victor R Preedy
Comparative effects of acute ethanol dosage on liver and muscle protein metabolism.
Biochemical pharmacology 2000;60(12):1773-85.
2000: R Koo-Ng; G Falkous; Matthew T Reilly; Timothy J Peters; David Mantle; Victor R Preedy
Carbonyl levels in type I and II fiber-rich muscles and their response to chronic ethanol feeding in vivo and hydroxyl and superoxide radicals in vitro.
Alcoholism, clinical and experimental research 2000;24(12):1862-8.
2000: Shlokarth Balupuri; P Buckley; M Mohamed; C Cornell; David Mantle; J Kirby; Derek M Manas; David Talbot
Assessment of non-heart-beating donor (NHBD) kidneys for viability on machine perfusion.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(11):1103-6.
2000: Shlokarth Balupuri; David Talbot; M F A El-Sheikh; Christopher P Snowden; Derek M Manas; J Kirby; David Mantle
Comparison of proteolytic enzymes and glutathione S-transferase levels in non-heart-beating donors' (NHBD) kidney perfusates.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2000;38(11):1099-102.
2000: David Mantle; F Eddeb; K Areni; Christopher P Snowden; David Mendelow
Comparative antioxidant potential of anaesthetics and perioperative drugs in vitro.
Clinica chimica acta; international journal of clinical chemistry 2000;301(1-2):41-53.
2000: David Mantle; F Eddeb; AT Pickering
Comparison of relative antioxidant activities of British medicinal plant species in vitro.
Journal of ethnopharmacology 2000;72(1-2):47-51.
2000: David Mantle; Vinood B Patel; HJ Why; S Ahmed; I Rahman; W MacNee; Wassif S Wassif; Peter J Richardson; Victor R Preedy
Effects of lisinopril and amlodipine on antioxidant status in experimental hypertension.
Clinica chimica acta; international journal of clinical chemistry 2000;299(1-2):1-10.
2000: Vinood B Patel; G Sandhu; M J Dunn; David Mantle; L M Rodrigues; J R Griffiths; Wassif S Wassif; Peter J Richardson; Victor R Preedy
Poor regression of myocardial hypertrophy following concomitant chronic alcohol ingestion and angiotensin converting enzyme (ACE) inhibition.
Life sciences 2000;67(12):1409-21.
2000: David Mantle; T W J Lennard; A T Pickering
Therapeutic applications of medicinal plants in the treatment of breast cancer: a review of their pharmacology, efficacy and tolerability.
Adverse drug reactions and toxicological reviews 2000;19(3):223-40.
2000: Shlokarth Balupuri; P Buckley; David Mantle; Christopher P Snowden; C Cornell; Derek M Manas; J Kirby; David Talbot
Non-heart-beating kidney donors.
Clinical transplantation 2000;14(3):266-7.
2000: M S Siddique; F Eddeb; David Mantle; David Mendelow
Extracts of Ginkgo biloba and Panax ginseng protect brain proteins from free radical induced oxidative damage in vitro.
Acta neurochirurgica. Supplement 2000;76():87-90.
2000: M Davis; David Mantle; David Mendelow
The role of proteolytic enzymes in focal ischaemic brain damage.
Acta neurochirurgica. Supplement 2000;76():261-4.
2000: Matthew Eliot Reilly; Godfrina McKoy; David Mantle; Timothy J Peters; Geoffrey Goldspink; Victor R Preedy
Protein and mRNA levels of the myosin heavy chain isoforms Ibeta, IIa, IIx and IIb in type I and type II fibre-predominant rat skeletal muscles in response to chronic alcohol feeding.
Journal of muscle research and cell motility 2000;21(8):763-73.
1999: David Mantle; V R Preedy
Free radicals as mediators of alcohol toxicity.
Adverse drug reactions and toxicological reviews 1999;18(4):235-52.
1999: Richard Wilkins; S Ahmed; David Mantle
Comparative effect of fenitrothion treatment on intracellular protease activities in insecticide-resistant and susceptible strains of Musca domestica L.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1999;124(3):337-43.
1999: Victor R Preedy; Vinood B Patel; Matthew Eliot Reilly; Peter J Richardson; G Falkous; David Mantle
Oxidants, antioxidants and alcohol: implications for skeletal and cardiac muscle.
Frontiers in bioscience : a journal and virtual library 1999;4():e58-66.
1999: David Mantle; G Falkous; Elaine K Perry
Effect of flavonoids on protease activities in human skeletal muscle tissue in vitro.
Clinica chimica acta; international journal of clinical chemistry 1999;285(1-2):13-20.
1999: David Mantle; G Falkous; D Walker
Quantification of protease activities in synovial fluid from rheumatoid and osteoarthritis cases: comparison with antioxidant and free radical damage markers.
Clinica chimica acta; international journal of clinical chemistry 1999;284(1):45-58.
1999: David Mantle; G Falkous; Timothy J Peters; Victor R Preedy
Effect of ethanol and acetaldehyde on intracellular protease activities in human liver, brain and muscle tissues in vitro.
Clinica chimica acta; international journal of clinical chemistry 1999;281(1-2):101-8.
1998: S Ahmed; Richard Wilkins; David Mantle
Effect of DDT exposure on protease activities in Musca domestica.
Biochemical Society transactions 1998;26(4):S357.
1998: S Ahmed; Richard Wilkins; David Mantle
Effects of organophosphate pesticides on protease activities in M. domestica and man.
Biochemical Society transactions 1998;26(4):S356.
1998: S Ahmed; Richard Wilkins; David Mantle
Effect of gamma irradiation on proteases activities in Musca domestica.
Biochemical Society transactions 1998;26(4):S355.
1998: F Eddeb; David Mendelow; D Turnbull; David Mantle
Differential susceptibility of brain proteins to oxidative damage.
Biochemical Society transactions 1998;26(4):S335.
1998: A Brown; M Wyatt; F Eddeb; David Mantle
Plasma lipid peroxidation during vascular surgery.
Biochemical Society transactions 1998;26(4):S334.
1998: F Eddeb; A Brown; AT Pickering; David Mendelow; David Mantle
Effect of antioxidant plant extracts on oxidative protein damage in brain tissue.
Biochemical Society transactions 1998;26(4):S333.
1998: S Ahmed; Richard Wilkins; David Mantle
Comparison of proteolytic enzyme activities in adults of insecticide resistant and susceptible strains of the housefly M. domestica L.
Insect biochemistry and molecular biology 1998;28(9):629-39.
1998: A Brown; S Dugdill; M Wyatt; P Cooper; David Mantle
Free radical analysis via ESR spectroscopy during vascular surgery.
Biochemical Society transactions 1998;26(2):S140.
1998: A Brown; S Dugdill; M Wyatt; David Mantle
Serum total antioxidant status during vascular surgery.
Biochemical Society transactions 1998;26(2):S127.
1998: M A Saleem; F M Williams; Richard Wilkins; A R Shakoori; David Mantle
Effect of Tri-O-cresyl phosphate (TOCP) on proteolytic enzyme activities in mouse liver in vivo.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 1998;17(1):69-73.
1997: Matthew Eliot Reilly; David Mantle; Peter J Richardson; J Salisbury; J Jones; Timothy J Peters; Victor R Preedy
Studies on the time-course of ethanol's acute effects on skeletal muscle protein synthesis: comparison with acute changes in proteolytic activity.
Alcoholism, clinical and experimental research 1997;21(5):792-8.
1997: David Mantle; M A Saleem; F M Williams; Richard Wilkins; A R Shakoori
Effect of pirimiphos-methyl on proteolytic enzyme activities in rat heart, kidney, brain and liver tissues in vivo.
Clinica chimica acta; international journal of clinical chemistry 1997;262(1-2):89-97.
1996: John Haycock; P Jones; J B Harris; David Mantle
Differential susceptibility of human skeletal muscle proteins to free radical induced oxidative damage: a histochemical, immunocytochemical and electron microscopical study in vitro.
Acta neuropathologica 1996;92(4):331-40.
1996: Pamela J Shaw; Paul Geoffrey Ince; G Falkous; David Mantle
Cytoplasmic, lysosomal and matrix protease activities in spinal cord tissue from amyotrophic lateral sclerosis (ALS) and control patients.
Journal of the neurological sciences 1996;139 Suppl():71-5.
1996: David Mantle; G Falkous; S Ishiura; P J Blanchard; Elaine K Perry
Comparison of proline endopeptidase activity in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Clinica chimica acta; international journal of clinical chemistry 1996;249(1-2):129-39.
1996: John Haycock; G Falkous; CA Maltin; MI Delday; David Mantle
Effect of prednisone on protease activities and structural protein levels in rat muscles in vivo.
Clinica chimica acta; international journal of clinical chemistry 1996;249(1-2):47-58.
1996: M A Faiz; G Falkous; J B Harris; David Mantle
Comparison of protease and related enzyme activities in snake venoms.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1996;113(1):199-204.
1995: Pamela J Shaw; Paul Geoffrey Ince; G Falkous; David Mantle
Oxidative damage to protein in sporadic motor neuron disease spinal cord.
Annals of neurology 1995;38(4):691-5.
1995: G Falkous; J B Harris; David Mantle
Effect of neurotoxic metal ions in vitro on proteolytic enzyme activities in human cerebral cortex.
Clinica chimica acta; international journal of clinical chemistry 1995;238(2):125-35.
1995: David Mantle; G Falkous; S Ishiura; Robert H Perry; Elaine K Perry
Comparison of cathepsin protease activities in brain tissue from normal cases and cases with Alzheimer's disease, Lewy body dementia, Parkinson's disease and Huntington's disease.
Journal of the neurological sciences 1995;131(1):65-70.
1995: M Abul Faiz; J B Harris; CA Maltin; David Mantle
Comparison of structural protein and proteolytic enzyme levels in degenerating and regenerating rat muscle induced by Notechis scutatus venom.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 1995;110(1):241-53.
1994: Paul Geoffrey Ince; Pamela J Shaw; J M Candy; David Mantle; L Tandon; WD Ehmann; William R Markesbery
Iron, selenium and glutathione peroxidase activity are elevated in sporadic motor neuron disease.
Neuroscience letters 1994;182(1):87-90.
1993: CA Maltin; P Jones; David Mantle
Effect of protease inhibitors and clenbuterol on the in vitro degradation of dystrophin by endogenous proteases in human skeletal muscle.
Bioscience reports 1993;13(3):159-67.
1993: P Blanchard; M Ellis; CA Maltin; G Falkous; J B Harris; David Mantle
Effect of growth promoters on pig muscle structural protein and proteolytic enzyme levels in vivo and in vitro.
Biochimie 1993;75(10):839-47.
1992: David Mantle; MI Delday; CA Maltin
Effect of clenbuterol on protease activities and protein levels in rat muscle.
Muscle & nerve 1992;15(4):471-8.
1991: A M Gibson; J A Biggins; BL Lauffart; David Mantle; J R McDermott
Human brain leucyl aminopeptidase: isolation, characterization and specificity against some neuropeptides.
Neuropeptides 1991;19(3):163-8.
1991: David Mantle; Elaine K Perry
Comparison of Ca(2+)-activated proteinase enzyme and endogenous inhibitor activity in brain tissue from normal and Alzheimer's disease cases.
Journal of the neurological sciences 1991;102(2):220-4.
1991: T Lees; David Mantle
Analysis of plasma lactate levels following ischemic exercise in patients with suspected metabolic myopathy.
Biochemical Society transactions 1991;19(2):216S.
1991: T Lees; CA Maltin; David Mantle
Effect of clenbuterol on the activity of proteolytic enzymes partially purified from rat skeletal muscle.
Biochemical Society transactions 1991;19(2):214S.
1991: T Lees; David Mantle; D Walker; P Jones; D Blake
Identification of aminopeptidases in sinovial fluid from rheumatoid arthritis patients.
Biochemical Society transactions 1991;19(2):215S.
1991: David Mantle; BL Lauffart; A Gibson
Purification and characterization of leucyl aminopeptidase and pyroglutamyl aminopeptidase from human skeletal muscle.
Clinica chimica acta; international journal of clinical chemistry 1991;197(1):35-45.
1991: David Mantle
Characterization of dipeptidyl and tripeptidyl aminopeptidases in human kidney soluble fraction.
Clinica chimica acta; international journal of clinical chemistry 1991;196(2-3):135-42.
1990: T Lees; David Mendelow; David Mantle
Analysis of ventricular fluid proteins in head-injured patients via SDS/polyacrylamide-gel electrophoresis.
Biochemical Society transactions 1990;18(4):668-9.
1990: T Lees; BL Lauffart; J McDermott; A Gibson; David Mantle
Purification and characterization of tripeptidyl-aminopeptidase from human cerebral cortex.
Biochemical Society transactions 1990;18(4):667.
1990: T Lees; BL Lauffart; A Hodson; A Skillen; David Mantle
Characterization of aminopeptidases in human kidney and urine.
Biochemical Society transactions 1990;18(4):666-7.
1990: David Mantle; Elaine K Perry
Comparison of aminopeptidase, dipeptidyl aminopeptidase and tripeptidyl aminopeptidase activities in brain tissue from normal and Alzheimer's disease cases.
Journal of the neurological sciences 1990;98(1):13-20.
1990: David Mantle; BL Lauffart; J McDermott; A Gibson
Characterization of aminopeptidases in human kidney soluble fraction.
Clinica chimica acta; international journal of clinical chemistry 1990;187(2):105-13.
1989: A M Gibson; J R McDermott; BL Lauffart; David Mantle
Specificity of action of human brain alanyl aminopeptidase on Leu-enkephalin and dynorphin-related peptides.
Neuropeptides 1989;13(4):259-62.
1989: David Mantle; BL Lauffart; Elaine K Perry; Robert H Perry
Comparison of major cortical aminopeptidase activity in normal brain and brain from patients with Alzheimer's disease.
Journal of the neurological sciences 1989;89(2-3):227-34.
1988: BL Lauffart; David Mantle
Rationalization of aminopeptidase activities in human skeletal muscle soluble extract.
Biochimica et biophysica acta 1988;956(3):300-6.
1988: J R McDermott; David Mantle; BL Lauffart; A M Gibson; J A Biggins
Purification and characterization of two soluble Cl(-)-activated arginyl aminopeptidases from human brain and their endopeptidase action on neuropeptides.
Journal of neurochemistry 1988;50(1):176-82.
1987: David Mantle; BL Lauffart; J Atack; R J Lane
Absence of biochemical heterogeneity in McArdle's disease. A high resolution SDS-polyacrylamide gel electrophoresis study.
Journal of the neurological sciences 1987;78(1):63-70.
1985: J R McDermott; David Mantle; BL Lauffart; A M Kidd
Purification and characterization of a neuropeptide-degrading aminopeptidase from human brain.
Journal of neurochemistry 1985;45(3):752-9.
1985: J R McDermott; David Mantle; J A Biggins; A M Kidd; K Davison; BL Lauffart; R J Pennington
Specificity of neuropeptide degradation by two calcium-activated neutral proteases from human skeletal muscle.
Life sciences 1985;37(8):725-30.
1985: David Mantle; BL Lauffart; J R McDermott; A M Kidd; R J Pennington
Purification and characterization of two Cl- -activated aminopeptidases hydrolysing basic termini from human skeletal muscle.
European journal of biochemistry / FEBS 1985;147(2):307-12.
1983: David Mantle; M F Hardy; BL Lauffart; J R McDermott; A I Smith; R J Pennington
Purification and characterization of the major aminopeptidase from human skeletal muscle.
The Biochemical journal 1983;211(3):567-73.