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Lucia Manzoli
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Research Profile (preview)
Chemicals & Drugs
Anatomy
Living Beings
Disorders
Physiology
Phenomena
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Network (preview)
60
Cocco, Lucio
52
Martelli, Alberto
40
Billi, Anna Maria
23
Faenza, Irene
11
Matteucci, Alessandro
9
Gilmour, Stewart
9
Follo, Matilde
9
Tabellini, Giovanna
8
Rubbini, S
8
Bortul, Roberta
7
Falconi, Mirella
6
Falà, Federica
6
Fiume, Roberta
6
Mazzotti, Giovanni
6
Bareggi, Renato
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All Publications
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2009: Follo Matilde Y; Finelli Carlo; Mongiorgi Sara; Clissa Cristina; Bosi Costanza; Testoni Nicoletta; Chiarini Francesca; Ramazzotti Giulia; Baccarani Michele; Martelli Alberto M; Manzoli Lucia; Martinelli Giovanni; Cocco Lucio
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16811-6.
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2009: Martelli Alberto M; Evangelisti Camilla; Chiarini Francesca; Grimaldi Cecilia; Manzoli Lucia; McCubrey James A
Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
Expert opinion on investigational drugs 2009;18(9):1333-49.
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2009: Follo Matilde Y; Finelli Carlo; Clissa Cristina; Mongiorgi Sara; Bosi Costanza; Martinelli Giovanni; Baccarani Michele; Manzoli Lucia; Martelli Alberto M; Cocco Lucio
Phosphoinositide-phospholipase C beta1 mono-allelic deletion is associated with myelodysplastic syndromes evolution into acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(5):782-90.
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2009: Cocco Lucio; Faenza Irene; Follo Matilde Y; Billi Anna Maria; Ramazzotti Giulia; Papa Veronica; Martelli Alberto M; Manzoli Lucia
Nuclear inositides: PI-PLC signaling in cell growth, differentiation and pathology.
Advances in enzyme regulation 2009;49(1):2-10.
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2008: Ramazzotti Giulia; Faenza Irene; Gaboardi Gian Carlo; Piazzi Manuela; Bavelloni Alberto; Fiume Roberta; Manzoli Lucia; Martelli Alberto M; Cocco Lucio
Catalytic activity of nuclear PLC-beta(1) is required for its signalling function during C2C12 differentiation.
Cellular signalling 2008;20(11):2013-21.
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2008: Follo M Y; Finelli C; Bosi C; Martinelli G; Mongiorgi S; Baccarani M; Manzoli L; Blalock W L; Martelli A M; Cocco L
PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2008;22(1):198-200.
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2008: Cocco Lucio; Faenza Irene; Follo Matilde Y; Ramazzotti Giulia; Gaboardi Gian Carlo; Billi Anna Maria; Martelli Alberto M; Manzoli Lucia
Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes.
Advances in enzyme regulation 2008;48():2-9.
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2008: Faenza Irene; Bregoli Lisa; Ramazzotti Giulia; Gaboardi Giancarlo; Follo Matilde Y; Mongiorgi Sara; Billi Anna Maria; Manzoli Lucia; Martelli Alberto M; Cocco Lucio
Nuclear phospholipase C beta1 and cellular differentiation.
Frontiers in bioscience : a journal and virtual library 2008;13():2452-63.
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2007: Evangelisti Camilla; Tazzari Pier Luigi; Riccio Massimo; Fiume Roberta; Hozumi Yasukazu; Falà Federica; Goto Kaoru; Manzoli Lucia; Cocco Lucio; Martelli Alberto M
Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3297-307.
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2007: Martelli A M; Tazzari P L; Evangelisti C; Chiarini F; Blalock W L; Billi A M; Manzoli L; McCubrey J A; Cocco L
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
Current medicinal chemistry 2007;14(19):2009-23.
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2007: Martelli Alberto M; Evangelist Camilla; Billi Anna Maria; Manzoli Lucia; Papa Veronica; Cocco Lucio
Intranuclear 3'-phosphoinositide metabolism and apoptosis protection in PC12 cells.
Acta bio-medica : Atenei Parmensis 2007;78 Suppl 1():113-9.
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2007: Cocco Lucio; Follo Matilde Y; Faenza Irene; Bavelloni Alberto; Billi Anna Maria; Martelli Alberto M; Manzoli Lucia
Nuclear inositide signaling: an appraisal of phospholipase C beta 1 behavior in myelodysplastic and leukemia cells.
Advances in enzyme regulation 2007;47():2-9.
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2006: Follo Matilde Y; Bosi Costanza; Finelli Carlo; Fiume Roberta; Faenza Irene; Ramazzotti Giulia; Gaboardi Gian Carlo; Manzoli Lucia; Cocco Lucio
Real-time PCR as a tool for quantitative analysis of PI-PLCbeta1 gene expression in myelodysplastic syndrome.
International journal of molecular medicine 2006;18(2):267-71.
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2006: Martelli Alberto M; Faenza Irene; Billi Anna Maria; Manzoli Lucia; Evangelisti Camilla; Falà Federica; Cocco Lucio
Intranuclear 3'-phosphoinositide metabolism and Akt signaling: new mechanisms for tumorigenesis and protection against apoptosis?
Cellular signalling 2006;18(8):1101-7.
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2005: Manzoli Lucia; Martelli Alberto M; Billi Anna Maria; Faenza Irene; Fiume Roberta; Cocco Lucio
Nuclear phospholipase C: involvement in signal transduction.
Progress in lipid research 2005;44(4):185-206.
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2005: Faenza Irene; Billi Anna Maria; Follo Matilde Yung; Fiume Roberta; Martelli Alberto Maria; Cocco Lucio; Manzoli Lucia
Nuclear phospholipase C signaling through type 1 IGF receptor and its involvement in cell growth and differentiation.
Anticancer research 2005;25(3B):2039-41.
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2005: Tabellini Giovanna; Cappellini Alessandra; Tazzari Pier Luigi; Falà Federica; Billi Anna Maria; Manzoli Lucia; Cocco Lucio; Martelli Alberto M
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
Journal of cellular physiology 2005;202(2):623-34.
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2005: Cocco Lucio; Manzoli Lucia; Palka Giandomenico; Martelli Alberto M
Nuclear phospholipase C beta1, regulation of the cell cycle and progression of acute myeloid leukemia.
Advances in enzyme regulation 2005;45():126-35.
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2004: Tabellini Giovanna; Billi Anna Maria; Falà Federica; Cappellini Alessandra; Evagelisti Camilla; Manzoli Lucia; Cocco Lucio; Martelli Alberto Maria
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells.
Cellular signalling 2004;16(11):1263-71.
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2004: Tabellini Giovanna; Tazzari Pier Luigi; Bortul Roberta; Billi Anna Maria; Conte Roberto; Manzoli Lucia; Cocco Lucio; Martelli Alberto M
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
British journal of haematology 2004;126(4):574-82.
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2004: Faenza Irene; Bavelloni Alberto; Fiume Roberta; Santi Patrizia; Martelli Alberto M; Maria Billi Anna; Lo Vasco Vincenza Rita; Manzoli Lucia; Cocco Lucio
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.
Journal of cellular physiology 2004;200(2):291-6.
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2004: Lo Vasco V R; Calabrese G; Manzoli L; Palka G; Spadano A; Morizio E; Guanciali-Franchi P; Fantasia D; Cocco L
Inositide-specific phospholipase c beta1 gene deletion in the progression of myelodysplastic syndrome to acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(6):1122-6.
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2004: Martelli A M; Falà F; Faenza I; Billi A M; Cappellini A; Manzoli L; Cocco L
Metabolism and signaling activities of nuclear lipids.
Cellular and molecular life sciences : CMLS 2004;61(10):1143-56.
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2004: Martelli Alberto M; Manzoli Lucia; Cocco Lucio
Nuclear inositides: facts and perspectives.
Pharmacology & therapeutics 2004;101(1):47-64.
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2004: Cocco Lucio; Manzoli Lucia; Barnabei Ottavio; Martelli Alberto M
Significance of subnuclear localization of key players of inositol lipid cycle.
Advances in enzyme regulation 2004;44():51-60.
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2004: Manzoli Lucia; Billi Anna Maria; Martelli Alberto Maria; Cocco Lucio
Regulation of nuclear phospholipase C activity.
Acta biochimica Polonica 2004;51(2):391-5.
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2003: Martelli A M; Faenza I; Billi A M; Falà F; Cocco L; Manzoli L
Nuclear protein kinase C isoforms: key players in multiple cell functions?
Histology and histopathology 2003;18(4):1301-12.
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2003: Martelli A M; Tazzari P L; Tabellini G; Bortul R; Billi A M; Manzoli L; Ruggeri A; Conte R; Cocco L
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(9):1794-805.
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2003: Bortul R; Tazzari P L; Cappellini A; Tabellini G; Billi A M; Bareggi R; Manzoli L; Cocco L; Martelli A M
Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(2):379-89.
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2003: Cocco Lucio; Manzoli Lucia; Barnabei Ottavio; Gilmour R Stewart; Martelli Alberto M
Re-examination of the significance of nuclear localization of PLCbeta1 in the likelihood of its involvement in neoplastic cell growth.
Advances in enzyme regulation 2003;43():1-13.
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2002: Martelli A M; Falcieri E; Zweyer M; Bortul R; Tabellini G; Cappellini A; Cocco L; Manzoli L
The controversial nuclear matrix: a balanced point of view.
Histology and histopathology 2002;17(4):1193-205.
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2002: Martelli Alberto M; Manzoli Lucia; Faenza Irene; Bortul Roberta; Billi Anna; Cocco Lucio
Nuclear inositol lipid signaling and its potential involvement in malignant transformation.
Biochimica et biophysica acta 2002;1603(1):11-7.
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2002: Peruzzi Daniela; Aluigi Michela; Manzoli Lucia; Billi Anna Maria; Di Giorgio Francesco Paolo; Morleo Manuela; Martelli Alberto M; Cocco Lucio
Molecular characterization of the human PLC beta1 gene.
Biochimica et biophysica acta 2002;1584(1):46-54.
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2002: Martelli A M; Bortul R; Tabellini G; Bareggi R; Manzoli L; Narducci P; Cocco L
Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways.
Cellular and molecular life sciences : CMLS 2002;59(7):1129-37.
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2002: Faenza Irene; Matteucci Alessandro; Bavelloni Alberto; Marmiroli Sandra; Martelli Alberto M; Gilmour R Stewart; Suh Pann-Ghill; Manzoli Lucia; Cocco Lucio
Nuclear PLCbeta(1) acts as a negative regulator of p45/NF-E2 expression levels in Friend erythroleukemia cells.
Biochimica et biophysica acta 2002;1589(3):305-10.
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2002: Martelli Alberto M; Bortul Roberta; Tabellini Giovanna; Faenza Irene; Cappellini Alessandra; Bareggi Renato; Manzoli Lucia; Cocco Lucio
Molecular characterization of protein kinase C-alpha binding to lamin A.
Journal of cellular biochemistry 2002;86(2):320-30.
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2001: Vitale M; Matteucci A; Manzoli L; Rodella L; Mariani A R; Zauli G; Falconi M; Billi A M; Martelli A M; Gilmour R S; Cocco L
Interleukin 2 activates nuclear phospholipase Cbeta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1789-91.
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2000: Martelli A M; Billi A M; Manzoli L; Faenza I; Aluigi M; Falconi M; De Pol A; Gilmour R S; Cocco L
Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation.
FEBS letters 2000;486(3):230-6.
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2000: Faenza I; Matteucci A; Manzoli L; Billi A M; Aluigi M; Peruzzi D; Vitale M; Castorina S; Suh P G; Cocco L
A role for nuclear phospholipase Cbeta 1 in cell cycle control.
The Journal of biological chemistry 2000;275(39):30520-4.
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2000: Peruzzi D; Calabrese G; Faenza I; Manzoli L; Matteucci A; Gianfrancesco F; Billi A M; Stuppia L; Palka G; Cocco L
Identification and chromosomal localisation by fluorescence in situ hybridisation of human gene of phosphoinositide-specific phospholipase C beta(1).
Biochimica et biophysica acta 2000;1484(2-3):175-82.
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2000: Martelli A M; Tabellini G; Bortul R; Manzoli L; Bareggi R; Baldini G; Grill V; Zweyer M; Narducci P; Cocco L
Enhanced nuclear diacylglycerol kinase activity in response to a mitogenic stimulation of quiescent Swiss 3T3 cells with insulin-like growth factor I.
Cancer research 2000;60(4):815-21.
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1999: Manzoli L; Billi A M; Faenza I; Matteucci A; Martelli A M; Peruzzi D; Falconi M; Rhee S G; Gilmour R S; Cocco L
Nuclear phospholipase C: a novel aspect of phosphoinositide signalling.
Anticancer research 1999;19(5A):3753-6.
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1999: Cocco L; Rubbini S; Manzoli L; Billi A M; Faenza I; Peruzzi D; Matteucci A; Artico M; Gilmour R S; Rhee S G
Inositides in the nucleus: presence and characterisation of the isozymes of phospholipase beta family in NIH 3T3 cells.
Biochimica et biophysica acta 1999;1438(2):295-9.
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1998: Matteucci A; Faenza I; Gilmour R S; Manzoli L; Billi A M; Peruzzi D; Bavelloni A; Rhee S G; Cocco L
Nuclear but not cytoplasmic phospholipase C beta 1 inhibits differentiation of erythroleukemia cells.
Cancer research 1998;58(22):5057-60.
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1998: Mazzotti G; Gobbi P; Manzoli L; Falconi M
Nuclear morphology during the S phase.
Microscopy research and technique 1998;40(5):418-31.
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1997: Billi A M; Matteucci A; Faenza I; Manzoli L; Rubbini S; Gilmour R S; Rhee S G; Cocco L
Control of expression of PLCbeta1 by LAC repressor system: relationship between nuclear PLCbeta1 overexpression and growth factor stimulation.
Biochemical and biophysical research communications 1997;241(1):122-6.
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1997: Manzoli L; Billi A M; Rubbini S; Bavelloni A; Faenza I; Gilmour R S; Rhee S G; Cocco L
Essential role for nuclear phospholipase C beta1 in insulin-like growth factor I-induced mitogenesis.
Cancer research 1997;57(11):2137-9.
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1997: Rubbini S; Cocco L; Manzoli L; Lutterman J; Billi A M; Matteucci A; Wirtz K W
Phosphoinositide signalling in nuclei of Friend cells: DMSO-induced differentiation reduces the association of phosphatidylinositol-transfer protein with the nucleus.
Biochemical and biophysical research communications 1997;230(2):302-5.
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1996: Manzoli L; Gilmour R S; Martelli A M; Billi A M; Cocco L
Nuclear inositol lipid cycle: a new central intermediary in signal transduction.
Anticancer research 1996;16(6A):3283-6.
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1995: Manzoli L; Billi A M; Gilmour R S; Martelli A M; Matteucci A; Rubbini S; Weber G; Cocco L
Phosphoinositide signaling in nuclei of Friend cells: tiazofurin down-regulates phospholipase C beta 1.
Cancer research 1995;55(14):2978-80.
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1995: Rizzi E; Falconi M; Rizzoli R; Baratta B; Manzoli L; Galanzi A; Lattanzi G; Mazzotti G
High-resolution FEISEM detection of DNA centromeric probes in HeLa metaphase chromosomes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995;43(4):413-9.
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1995: Martelli A M; Cataldi A; Manzoli L; Billi A M; Rubbini S; Gilmour R S; Cocco L
Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation.
Cellular signalling 1995;7(1):53-6.
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1995: Martelli A M; Manzoli L; Rubbini S; Billi A M; Bareggi R; Cocco L
The protein composition of Friend cell nuclear matrix stabilized by various treatments. Different recovery of nucleolar proteins B23 and C23 and nuclear lamins.
Biology of the cell / under the auspices of the European Cell Biology Organization 1995;83(1):15-22.
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1994: Rizzoli R; Rizzi E; Falconi M; Galanzi A; Baratta B; Lattanzi G; Vitale M; Mazzotti G; Manzoli L
High resolution detection of uncoated metaphase chromosomes by means of field emission scanning electron microscopy.
Chromosoma 1994;103(6):393-400.
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1994: Neri L M; Billi A M; Manzoli L; Rubbini S; Gilmour R S; Cocco L; Martelli A M
Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF.
FEBS letters 1994;347(1):63-8.
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1994: Martelli A M; Billi A M; Gilmour R S; Neri L M; Manzoli L; Ognibene A; Cocco L
Phosphoinositide signaling in nuclei of Friend cells: phospholipase C beta down-regulation is related to cell differentiation.
Cancer research 1994;54(10):2536-40.
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1994: Martelli A M; Neri L M; Zamai L; Bareggi R; Manzoli L; Cocco L
6-Iodoacetamidofluorescein labelling to assess the state of sulphhydril groups after thermal stabilization of isolated nuclei.
The Histochemical journal 1994;26(2):179-88.
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1992: Martelli A M; Gilmour R S; Bertagnolo V; Neri L M; Manzoli L; Cocco L
Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells.
Nature 1992;358(6383):242-5.
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1992: Martelli A M; Billi A M; Gilmour R S; Manzoli L; Di Primio R; Cocco L
Mouse and human hemopoietic cell lines of erythroid lineage express lamins A,B and C.
Biochemical and biophysical research communications 1992;185(1):271-6.
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1992: Martelli A M; Falcieri E; Gobbi P; Manzoli L; Cataldi A; Rana R A; Cocco L
Further considerations on the thermal stabilization of the nuclear matrix in mouse erythroleukemia cells.
Cell biology international reports 1992;16(4):307-17.
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1992: Rizzoli R; Baratta B; Maraldi N M; Falconi M; Galanzi A; Papa S; Vitale M; Rizzi E; Manzoli L; Mazzotti G
DNA synthesis progression in 3T3 synchronized fibroblasts: a high resolution approach.
Histochemistry 1992;97(2):181-7.
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1991: Martelli A M; Falcieri E; Gobbi P; Manzoli L; Gilmour R S; Cocco L
Heat-induced stabilization of the nuclear matrix: a morphological and biochemical analysis in murine erythroleukemia cells.
Experimental cell research 1991;196(2):216-25.
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1991: Martelli A M; Gilmour R S; Neri L M; Manzoli L; Corps A N; Cocco L
Mitogen-stimulated events in nuclei of Swiss 3T3 cells. Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis.
FEBS letters 1991;283(2):243-6.
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1991: Vitale M; Rizzoli R; Mazzotti G; Zamai L; Galanzi A; Rizzi E; Manzoli L; Matteucci A; Papa S
Characterization and cell cycle kinetics of hepatocytes during rat liver regeneration: in vivo BrdUrd incorporation analysed by flow cytometry and electron microscopy.
Cell proliferation 1991;24(3):331-8.
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1991: Vitale M; Zamai L; Neri L M; Manzoli L; Facchini A; Papa S
Natural killer function in flow cytometry: identification of human lymphoid subsets able to bind to the NK sensitive target K562.
Cytometry 1991;12(8):717-22.
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1990: Rana R; Vitale M; Mazzotti G; Manzoli L; Papa S
Radiosensitivity of human natural killer cells: binding and cytotoxic activities of natural killer cell subsets.
Radiation research 1990;124(1):96-102.
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1990: Martelli A M; Billi A M; De Marchis C; Manzoli L; Cocco L
Probing the sulfhydryl groups of nuclear matrix proteins with 6-iodoacetamidofluorescein.
Cell biology international reports 1990;14(5):409-18.
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1990: Marinelli F; Falcieri E; Squarzoni S; Del Coco R; Zini N; Manzoli L; Maraldi N M
Image analysis of the chromatin organization in the nuclear domains of freeze fractured hepatocytes and lymphocytes.
Biology of the cell / under the auspices of the European Cell Biology Organization 1990;70(3):107-19.
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1989: Caramelli E; Papa S; Billi A M; Vitale M; Bartoletti A; Manzoli L; Capitani S
Liposome-nucleus interactions. Flow cytometric study on the role of the nuclear surface.
Cell biochemistry and function 1989;7(1):71-4.
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1989: Vitale M; Neri L M; Manzoli L; Galanzi A; Rana R; Antonucci A; Papa S
Improved bromodeoxyuridine/DNA analysis by anti-BudR monoclonal antibody versus right angle light scatter.
Histochemistry 1989;93(1):9-11.
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1988: Miscia S; Cataldi A; Ognibene A; Martelli A M; Manzoli L; Billi A M; De Marchis C; Cocco L
Evidence for a reduction of the replicative activity of matrix-bound DNA polymerase alpha following treatment with phospholipase C.
Cell biology international reports 1988;12(5):347-54.
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1987: Cocco L; Martelli A M; Billi A M; Cataldi A; Miscia S; Mottola M R; Manzoli L
Phospholipids as components of the nuclear matrix: their possible biological significance.
Basic and applied histochemistry 1987;31(3):413-9.
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