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CJ March

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

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Mouse

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Cloning, Molecular

Chemicals & Drugs

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Publications

TOP 3
Arie Zask; Y Gu; J Donald Albright; Xumei Du; M Hogan; Jeremy I Levin; James M Chen; Loran M Killar; Amy Sung; John F DiJoseph; Michele A Sharr; Catherine E Roth; S Skala; Guixian Jin; Rebecca Cowling; Ken Mohler; Dauphine Barone; Roy Black; CJ March; Jerauld S Skotnicki
Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors.
Jeremy I Levin; James M Chen; Mila T Du; Frances C Nelson; Loran M Killar; S Skala; Amy Sung; Guixian Jin; Rebecca Cowling; Dauphine Barone; CJ March; Ken Mohler; Roy A Black; Jerauld S Skotnicki
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 2: SAR of the acetylenic P1' group.
Jeremy I Levin; James M Chen; Mila T Du; Frances C Nelson; T Wehr; John F DiJoseph; Loran M Killar; S Skala; Amy Sung; Michele A Sharr; Catherine E Roth; Guixian Jin; Rebecca Cowling; L Di; M Sherman; Zhang B Xu; CJ March; Ken Mohler; Roy A Black; Jerauld S Skotnicki
The discovery of anthranilic acid-based MMP inhibitors. Part 3: incorporation of basic amines.

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All Publications

2003: Arie Zask; Y Gu; J Donald Albright; Xumei Du; M Hogan; Jeremy I Levin; James M Chen; Loran M Killar; Amy Sung; John F DiJoseph; Michele A Sharr; Catherine E Roth; S Skala; Guixian Jin; Rebecca Cowling; Ken Mohler; Dauphine Barone; Roy Black; CJ March; Jerauld S Skotnicki
Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors.
Bioorganic & medicinal chemistry letters 2003;13(8):1487-90.
2002: Jeremy I Levin; James M Chen; Mila T Du; Frances C Nelson; Loran M Killar; S Skala; Amy Sung; Guixian Jin; Rebecca Cowling; Dauphine Barone; CJ March; Ken Mohler; Roy A Black; Jerauld S Skotnicki
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 2: SAR of the acetylenic P1' group.
Bioorganic & medicinal chemistry letters 2002;12(8):1199-202.
2001: Jeremy I Levin; James M Chen; Mila T Du; Frances C Nelson; T Wehr; John F DiJoseph; Loran M Killar; S Skala; Amy Sung; Michele A Sharr; Catherine E Roth; Guixian Jin; Rebecca Cowling; L Di; M Sherman; Zhang B Xu; CJ March; Ken Mohler; Roy A Black; Jerauld S Skotnicki
The discovery of anthranilic acid-based MMP inhibitors. Part 3: incorporation of basic amines.
Bioorganic & medicinal chemistry letters 2001;11(22):2975-8.
2001: Jeremy I Levin; J Chen; Mila Du; M Hogan; S Kincaid; Frances C Nelson; Aranapakam M Venkatesan; T Wehr; Arie Zask; John F DiJoseph; Loran M Killar; S Skala; Amy Sung; Michele A Sharr; C Roth; Guixian Jin; Rebecca Cowling; Ken Mohler; Roy A Black; CJ March; Jerauld S Skotnicki
The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups.
Bioorganic & medicinal chemistry letters 2001;11(16):2189-92.
1998: Jacques J Peschon; JL Slack; P Reddy; Kim L Stocking; Susan W Sunnarborg; David C Lee; William E Russell; Beverly J Castner; Richard S Johnson; JN Fitzner; R W Boyce; N Nelson; Carl J Kozlosky; Martin F Wolfson; Charles T Rauch; Douglas Pat Cerretti; Raymond J Paxton; CJ March; Roy A Black
An essential role for ectodomain shedding in mammalian development.
Science (New York, N.Y.) 1998;282(5392):1281-4.
1998: Klaus Maskos; Carlos Fernandez-Catalan; Robert Huber; Gleb P Bourenkov; Hans D Bartunik; G A Ellestad; P Reddy; Martin F Wolfson; Charles T Rauch; Beverly J Castner; R Davis; H R Clarke; M Petersen; JN Fitzner; Douglas Pat Cerretti; CJ March; Raymond J Paxton; Roy A Black; Wolfram Bode
Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3408-12.
1997: Roy A Black; Charles T Rauch; Carl J Kozlosky; Jacques J Peschon; JL Slack; Martin F Wolfson; Beverly J Castner; Kim L Stocking; P Reddy; S Srinivasan; N Nelson; Norman Boiani; Kenneth Schooley; Mary J Gerhart; R Davis; JN Fitzner; Richard S Johnson; Raymond J Paxton; CJ March; Douglas Pat Cerretti
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells.
Nature 1997;385(6618):729-33.
1996: R C Hoffman; Franklin J Moy; V Price; J Richardson; D Kaubisch; E A Frieden; J D Krakover; Beverly J Castner; J King; CJ March; Robert Powers
Resonance assignments for Oncostatin M, a 24-kDa alpha-helical protein.
Journal of biomolecular NMR 1996;7(4):273-82.
1996: Franklin O Smith; Charles T Rauch; D E Williams; CJ March; D Arthur; Joanne M Hilden; BC Lampkin; Jonathan D Buckley; C V Buckley; William G Woods; P A Dinndorf; P Sorensen; J Kersey; D Hammond; Irwin D Bernstein
The human homologue of rat NG2, a chondroitin sulfate proteoglycan, is not expressed on the cell surface of normal hematopoietic cells but is expressed by acute myeloid leukemia blasts from poor-prognosis patients with abnormalities of chromosome band 11q23.
Blood 1996;87(3):1123-33.
1995: Sucha Sudarsanam; R F DuBose; CJ March; S Srinivasan
Modeling protein loops using a phi i + 1, psi i dimer database.
Protein science : a publication of the Protein Society 1995;4(7):1412-20.
1995: R C Hoffman; Beverly J Castner; Mary J Gerhart; M G Gibson; B D Rasmussen; CJ March; J Weatherbee; M Tsang; Alla Gustchina; C Schalk-Hihi
Direct evidence of a heterotrimeric complex of human interleukin-4 with its receptors.
Protein science : a publication of the Protein Society 1995;4(3):382-6.
1994: Sucha Sudarsanam; CJ March; S Srinivasan
Homology modeling of divergent proteins.
Journal of molecular biology 1994;241(2):143-9.
1994: R C Hoffman; C Schalk-Hihi; Beverly J Castner; M G Gibson; B D Rasmussen; Alexander Zdanov; Alla Gustchina; CJ March; Alexander Wlodawer
Stoichiometry of the complex of human interleukin-4 with its receptor.
FEBS letters 1994;347(1):17-21.
1993: S Srinivasan; CJ March; Sucha Sudarsanam
Sequence into structure.
Bio/technology (Nature Publishing Company) 1993;11(13):1579-80.
1993: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
The high-resolution, three-dimensional solution structure of human interleukin-4 determined by multidimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1993;32(26):6744-62.
1993: W C Fanslow; Melanie Spriggs; Charles T Rauch; K N Clifford; B M Macduff; Steven F Ziegler; Kenneth Schooley; K M Mohler; CJ March; Richard J Armitage
Identification of a distinct low-affinity receptor for human interleukin-4 on pre-B cells.
Blood 1993;81(11):2998-3005.
1993: S Srinivasan; CJ March; Sucha Sudarsanam
An automated method for modeling proteins on known templates using distance geometry.
Protein science : a publication of the Protein Society 1993;2(2):277-89.
1993: M P Beckmann; R B Gayle; Douglas Pat Cerretti; CJ March; S Srinivasan; P R Sleath
Structural and functional characterization of the interleukin-8 receptors.
Advances in experimental medicine and biology 1993;351():155-69.
1992: S R Kronheim; A Mumma; T Greenstreet; P J Glackin; K Van Ness; CJ March; Roy A Black
Purification of interleukin-1 beta converting enzyme, the protease that cleaves the interleukin-1 beta precursor.
Archives of biochemistry and biophysics 1992;296(2):698-703.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy.
Science (New York, N.Y.) 1992;256(5064):1673-7.
1992: Sucha Sudarsanam; G D Virca; CJ March; S Srinivasan
An approach to computer-aided inhibitor design: application to cathepsin L.
Journal of computer-aided molecular design 1992;6(3):223-33.
1992: Daniel S Garrett; Robert Powers; CJ March; E A Frieden; G Marius Clore; Angela M Gronenborn
Determination of the secondary structure and folding topology of human interleukin-4 using three-dimensional heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4347-53.
1992: Robert Powers; Daniel S Garrett; CJ March; E A Frieden; Angela M Gronenborn; G Marius Clore
1H, 15N, 13C, and 13CO assignments of human interleukin-4 using three-dimensional double- and triple-resonance heteronuclear magnetic resonance spectroscopy.
Biochemistry 1992;31(17):4334-46.
1992: Douglas Pat Cerretti; Carl J Kozlosky; B Mosley; N Nelson; K Van Ness; T A Greenstreet; CJ March; S R Kronheim; Teresa Druck; Linda Cannizzaro
Molecular cloning of the interleukin-1 beta converting enzyme.
Science (New York, N.Y.) 1992;256(5053):97-100.
1992: James M Burns; Wayne Shreffler; D E Rosman; P R Sleath; CJ March; Steven G Reed
Identification and synthesis of a major conserved antigenic epitope of Trypanosoma cruzi.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1239-43.
1991: James M Burns; J M Scott; Edgar M Carvalho; DM Russo; CJ March; K P Van Ness; Steven G Reed
Characterization of a membrane antigen of Leishmania amazonensis that stimulates human immune responses.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(2):742-8.
1991: B M Curtis; Scott Presnell; S Srinivasan; H Sassenfeld; R Klinke; E Jeffery; D Cosman; CJ March; Fred Cohen
Experimental and theoretical studies of the three-dimensional structure of human interleukin-4.
Proteins 1991;11(2):111-9.
1990: Charles R Maliszewski; CJ March; MA Schoenborn; S Gimpel; L Shen
Expression cloning of a human Fc receptor for IgA.
The Journal of experimental medicine 1990;172(6):1665-72.
1990: A Larsen; T Davis; B M Curtis; S Gimpel; John E Sims; David Cosman; L Park; E Sorensen; CJ March; CA Smith
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
The Journal of experimental medicine 1990;172(6):1559-70.
1990: D M Anderson; S D Lyman; A Baird; J M Wignall; J Eisenman; Charles T Rauch; CJ March; H Scott Boswell; S D Gimpel; David Cosman
Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms.
Cell 1990;63(1):235-43.
1990: D E Williams; J Eisenman; A Baird; Charles T Rauch; K Van Ness; CJ March; L S Park; U Martin; D Y Mochizuki; H Scott Boswell
Identification of a ligand for the c-kit proto-oncogene.
Cell 1990;63(1):167-74.
1990: P R Sleath; Ronald Hendrickson; S R Kronheim; CJ March; Roy A Black
Substrate specificity of the protease that processes human interleukin-1 beta.
The Journal of biological chemistry 1990;265(24):14526-8.
1990: D Cosman; S D Lyman; R L Idzerda; M P Beckmann; L S Park; RG Goodwin; CJ March
A new cytokine receptor superfamily.
Trends in biochemical sciences 1990;15(7):265-70.
1990: RG Goodwin; D Friend; Steven F Ziegler; R Jerzy; B A Falk; S Gimpel; David Cosman; Steven K Dower; CJ March; A E Namen
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.
Cell 1990;60(6):941-51.
1990: R L Idzerda; CJ March; B Mosley; S D Lyman; T Vanden Bos; S D Gimpel; W S Din; Kenneth H Grabstein; M B Widmer; L S Park
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
The Journal of experimental medicine 1990;171(3):861-73.
1989: John E Sims; R B Acres; C E Grubin; C J McMahan; J M Wignall; CJ March; Steven K Dower
Cloning the interleukin 1 receptor from human T cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8946-50.
1989: B Mosley; M P Beckmann; CJ March; R L Idzerda; S D Gimpel; T VandenBos; D Friend; A Alpert; D Anderson; J Jackson
The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms.
Cell 1989;59(2):335-48.
1989: Roy A Black; S R Kronheim; J E Merriam; CJ March; T P Hopp
A pre-aspartate-specific protease from human leukocytes that cleaves pro-interleukin-1 beta.
The Journal of biological chemistry 1989;264(10):5323-6.
1989: Byron Gallis; J Mehl; K S Prickett; J A Martin; J Merriam; CJ March; Douglas Pat Cerretti
Antimicrobial activity of synthetic bactenecin.
Biotechnology therapeutics 1989;1(4):335-46.
1988: R T Libby; David Cosman; M K Cooney; J E Merriam; CJ March; T P Hopp
Human rhinovirus 3C protease: cloning and expression of an active form in Escherichia coli.
Biochemistry 1988;27(17):6262-8.
1988: John E Sims; CJ March; David Cosman; M B Widmer; H R MacDonald; C J McMahan; C E Grubin; J M Wignall; J L Jackson; S M Call
cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily.
Science (New York, N.Y.) 1988;241(4865):585-9.
1988: Roy A Black; S R Kronheim; M Cantrell; M C Deeley; CJ March; K S Prickett; J Wignall; P J Conlon; David Cosman; T P Hopp
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.
The Journal of biological chemistry 1988;263(19):9437-42.
1988: A E Namen; S Lupton; K Hjerrild; J Wignall; D Y Mochizuki; A Schmierer; B Mosley; CJ March; D Urdal; S Gillis
Stimulation of B-cell progenitors by cloned murine interleukin-7.
Nature 1988;333(6173):571-3.
1988: A E Namen; A E Schmierer; CJ March; R W Overell; L S Park; D L Urdal; D Y Mochizuki
B cell precursor growth-promoting activity. Purification and characterization of a growth factor active on lymphocyte precursors.
The Journal of experimental medicine 1988;167(3):988-1002.
1987: R T Libby; G Braedt; S R Kronheim; CJ March; D L Urdal; T A Chiaverotti; R J Tushinski; D Y Mochizuki; T P Hopp; David Cosman
Expression and purification of native human granulocyte-macrophage colony-stimulating factor from an Escherichia coli secretion vector.
DNA (Mary Ann Liebert, Inc.) 1987;6(3):221-9.
1987: V Price; D Mochizuki; CJ March; David Cosman; M C Deeley; R Klinke; W Clevenger; S Gillis; P Baker; D Urdal
Expression, purification and characterization of recombinant murine granulocyte-macrophage colony-stimulating factor and bovine interleukin-2 from yeast.
Gene 1987;55(2-3):287-93.
1986: J D Watson; P S Crosier; CJ March; P J Conlon; D Y Mochizuki; S Gillis; D L Urdal
Purification to homogeneity of a human hematopoietic growth factor that stimulates the growth of a murine interleukin 3-dependent cell line.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(3):854-7.
1986: T P Hopp; S K Dower; CJ March
The molecular forms of interleukin-1.
Immunologic research 1986;5(4):271-80.
1985: Steven K Dower; S R Kronheim; CJ March; P J Conlon; T P Hopp; S Gillis; D L Urdal
Detection and characterization of high affinity plasma membrane receptors for human interleukin 1.
The Journal of experimental medicine 1985;162(2):501-15.
1985: P J Conlon; K H Luk; L S Park; CJ March; T P Hopp; D L Urdal
Generation of anti-peptide monoclonal antibodies which recognize mature CSF-2 alpha (IL 3) protein.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(1):328-32.
1985: CJ March; B Mosley; A Larsen; Douglas Pat Cerretti; G Braedt; V Price; S Gillis; C S Henney; S R Kronheim; K Grabstein
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs.
Nature 1985;315(6021):641-7.
1985: S R Kronheim; CJ March; S K Erb; P J Conlon; D Y Mochizuki; T P Hopp
Human interleukin 1. Purification to homogeneity.
The Journal of experimental medicine 1985;161(3):490-502.
1984: D L Urdal; CJ March; S Gillis; A Larsen; S K Dower
Purification and chemical characterization of the receptor for interleukin 2 from activated human T lymphocytes and from a human T-cell lymphoma cell line.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(20):6481-5.
1984: D L Urdal; D Mochizuki; P J Conlon; CJ March; M L Remerowski; J Eisenman; C Ramthun; S Gillis
Lymphokine purification by reversed-phase high-performance liquid chromatography.
Journal of chromatography 1984;296():171-9.