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Graeme Mardon

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Erin Haase Gilbert; Su-Jin Kwak; Rui Chen; Graeme Mardon
Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation.
Meng Jin; Barbara Jusiak; Zengliang Bai; Graeme Mardon
Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survival.
Barbara Jusiak; Abuduaini Abulimiti; Rui Chen; Nele Haelterman; Graeme Mardon
MAPK target sites of eyes absent are not required for eye development or survival in Drosophila.

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All Publications

2013: Erin Haase Gilbert; Su-Jin Kwak; Rui Chen; Graeme Mardon
Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation.
PloS one 2013;8(4):e60908.
2013: Meng Jin; Barbara Jusiak; Zengliang Bai; Graeme Mardon
Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survival.
PloS one 2013;8(3):e58818.
2012: Barbara Jusiak; Abuduaini Abulimiti; Rui Chen; Nele Haelterman; Graeme Mardon
MAPK target sites of eyes absent are not required for eye development or survival in Drosophila.
PloS one 2012;7(12):e50776.
2011: Xia Wang; Kun Zhang; Richard A Lewis; Emad B Abboud; Ali A Al-Rajhi; Ming Cao; Xianfeng Chen; Richard A Gibbs; Athurva Gore; Zhe Li; James R Lupski; Graeme Mardon; Donna Muzny; Claire Patenia; Hui Wang; Rui Chen
Whole-exome sequencing identifies ALMS1, IQCB1, CNGA3, and MYO7A mutations in patients with Leber congenital amaurosis.
Human mutation 2011;32(12):1450-9.
2011: Aimée E Anderson; Umesh C Karandikar; Kathryn L Pepple; Zhihong Chen; Andreas Bergmann; Graeme Mardon
The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development.
Development (Cambridge, England) 2011;138(10):1957-66.
2011: Wojciech Wiszniewski; Richard Alan Lewis; David Wayne Stockton; Jianlan Peng; Graeme Mardon; Rui Chen; James R Lupski
Potential involvement of more than one locus in trait manifestation for individuals with Leber congenital amaurosis.
Human genetics 2011;129(3):319-27.
2009: Mardelle Atkins; Graeme Mardon
Signaling in the third dimension: the peripodial epithelium in eye disc development.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(9):2139-48.
2009: Hui Wang; Anneke I den Hollander; Yalda Moayedi; Abuduaini Abulimiti; Yumei Li; Rob W J Collin; Carel B Hoyng; Irma Lopez; Emad B Abboud; Ali A Al-Rajhi; Molly S Bray; Richard Alan Lewis; James R Lupski; Graeme Mardon; Robert K Koenekoop; Rui Chen
Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa.
American journal of human genetics 2009;84(3):380-7.
2008: Kathryn L Pepple; Mardelle Atkins; Koen J T Venken; Kari Wellnitz; Mark Harding; Benjamin J Frankfort; Graeme Mardon
Two-step selection of a single R8 photoreceptor: a bistable loop between senseless and rough locks in R8 fate.
Development (Cambridge, England) 2008;135(24):4071-9.
2007: Kathryn L Pepple; Aimée E Anderson; Benjamin J Frankfort; Graeme Mardon
A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin.
Genetics 2007;175(1):125-41.
2006: Edwin J Ostrin; Yumei Li; Kristi Hoffman; Jing Liu; Keqing Wang; Li Zhang; Graeme Mardon; Rui Chen
Genome-wide identification of direct targets of the Drosophila retinal determination protein Eyeless.
Genome research 2006;16(4):466-76.
2006: Richard J Davis; Yakov Pesah; Mark Harding; Richard Paylor; Graeme Mardon
Mouse Dach2 mutants do not exhibit gross defects in eye development or brain function.
Genesis (New York, N.Y. : 2000) 2006;44(2):84-92.
2005: Patricia Purcell; Guillermo Oliver; Graeme Mardon; Amy L Donner; Richard L Maas
Pax6-dependence of Six3, Eya1 and Dach1 expression during lens and nasal placode induction.
Gene expression patterns : GEP 2005;6(1):110-8.
2005: Rui Chen; Graeme Mardon
Keeping an eye on the fly genome.
Developmental biology 2005;282(2):285-93.
2005: Kartik S Pappu; Edwin J Ostrin; Brooke W Middlebrooks; Beril Tavsanli Sili; Rui Chen; Mardelle R Atkins; Richard Gibbs; Graeme Mardon
Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund.
Development (Cambridge, England) 2005;132(12):2895-905.
2005: Yakov Pesah; Heather Burgess; Brooke W Middlebrooks; Kari Ronningen; Jude Prosser; Vijaya Tirunagaru; John Zysk; Graeme Mardon
Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila.
Genesis (New York, N.Y. : 2000) 2005;41(4):154-9.
2004: Pedro Domingos; Samara Brown; Rosa Barrio; Kajan Ratnakumar; Benjamin J Frankfort; Graeme Mardon; Hermann Steller; Bertrand Mollereau
Regulation of R7 and R8 differentiation by the spalt genes.
Developmental biology 2004;273(1):121-33.
2004: Beril C Tavsanli; Edwin J Ostrin; Heather Burgess; Brooke W Middlebrooks; Tony A Pham; Graeme Mardon
Structure-function analysis of the Drosophila retinal determination protein Dachshund.
Developmental biology 2004;272(1):231-47.
2004: Yakov Pesah; Tuan Pham; Heather Burgess; Brooke W Middlebrooks; Patrik Verstreken; Yi Zhou; Mark Harding; Hugo J Bellen; Graeme Mardon
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress.
Development (Cambridge, England) 2004;131(9):2183-94.
2004: Benjamin J Frankfort; Kathryn L Pepple; Mark Mamlouk; Matthew F Rose; Graeme Mardon
Senseless is required for pupal retinal development in Drosophila.
Genesis (New York, N.Y. : 2000) 2004;38(4):182-94.
2004: Benjamin J Frankfort; Graeme Mardon
Senseless represses nuclear transduction of Egfr pathway activation.
Development (Cambridge, England) 2004;131(3):563-70.
2004: Kartik S Pappu; Graeme Mardon
Genetic control of retinal specification and determination in Drosophila.
The International journal of developmental biology 2004;48(8-9):913-24.
2003: Jayanagendra P Rayapureddi; Chandramohan Kattamuri; Brian D Steinmetz; Benjamin J Frankfort; Edwin J Ostrin; Graeme Mardon; Rashmi S Hegde
Eyes absent represents a class of protein tyrosine phosphatases.
Nature 2003;426(6964):295-8.
2003: Richard J Davis; Beril C Tavsanli; Cheryl Dittrich; Uwe Walldorf; Graeme Mardon
Drosophila retinal homeobox (drx) is not required for establishment of the visual system, but is required for brain and clypeus development.
Developmental biology 2003;259(2):272-87.
2003: Kartik S Pappu; Rui Chen; Brooke W Middlebrooks; Catherine Woo; Ulrike Heberlein; Graeme Mardon
Mechanism of hedgehog signaling during Drosophila eye development.
Development (Cambridge, England) 2003;130(13):3053-62.
2002: Yoshiko Inoue; Taro Mito; Katsuyuki Miyawaki; Kyoko Matsushima; Yohei Shinmyo; Tiffany A Heanue; Graeme Mardon; Hideyo Ohuchi; Sumihare Noji
Correlation of expression patterns of homothorax, dachshund, and Distal-less with the proximodistal segmentation of the cricket leg bud.
Mechanisms of development 2002;113(2):141-8.
2002: Benjamin J Frankfort; Graeme Mardon
R8 development in the Drosophila eye: a paradigm for neural selection and differentiation.
Development (Cambridge, England) 2002;129(6):1295-306.
2002: Tiffany A Heanue; Richard J Davis; David H Rowitch; Andreas Kispert; Andrew P McMahon; Graeme Mardon; Clifford J Tabin
Dach1, a vertebrate homologue of Drosophila dachshund, is expressed in the developing eye and ear of both chick and mouse and is regulated independently of Pax and Eya genes.
Mechanisms of development 2002;111(1-2):75-87.
2001: Benjamin J Frankfort; R Nolo; Z Zhang; Hugo J Bellen; Graeme Mardon
senseless repression of rough is required for R8 photoreceptor differentiation in the developing Drosophila eye.
Neuron 2001;32(3):403-14.
2001: Beril C Tavsanli; Kartik S Pappu; Sunil Q Mehta; Graeme Mardon
Dbest1, a Drosophila homolog of human Bestrophin, is not required for viability or photoreceptor integrity.
Genesis (New York, N.Y. : 2000) 2001;31(3):130-6.
2001: Richard J Davis; W Shen; Y I Sandler; Tiffany A Heanue; Graeme Mardon
Characterization of mouse Dach2, a homologue of Drosophila dachshund.
Mechanisms of development 2001;102(1-2):169-79.
2001: R J Davis; W Shen; Y I Sandler; M Amoui; Patricia Purcell; R Maas; Ching-Nan Ou; Hannes Vogel; Arthur L Beaudet; Graeme Mardon
Dach1 mutant mice bear no gross abnormalities in eye, limb, and brain development and exhibit postnatal lethality.
Molecular and cellular biology 2001;21(5):1484-90.
2000: S R Martini; Gregg Roman; S Meuser; Graeme Mardon; Ronald L Davis
The retinal determination gene, dachshund, is required for mushroom body cell differentiation.
Development (Cambridge, England) 2000;127(12):2663-72.
1999: Tiffany A Heanue; R Reshef; Richard J Davis; Graeme Mardon; G Oliver; S Tomarev; Andrew B Lassar; Clifford J Tabin
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation.
Genes & development 1999;13(24):3231-43.
1999: Richard J Davis; W Shen; Tiffany A Heanue; Graeme Mardon
Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs.
Development genes and evolution 1999;209(9):526-36.
1999: Rui Chen; Georg Halder; Zhen Zhang; Graeme Mardon
Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila.
Development (Cambridge, England) 1999;126(5):935-43.
1997: Rui Chen; M Amoui; Z Zhang; Graeme Mardon
Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila.
Cell 1997;91(7):893-903.
1997: W Shen; Graeme Mardon
Ectopic eye development in Drosophila induced by directed dachshund expression.
Development (Cambridge, England) 1997;124(1):45-52.