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Jose Marin

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R Rosales; Fermin Sanchez de Medina; J Vaquero; O Martinez-Augustin; Maria J Monte; P Requena; Marta R Romero; Jose J G Marin
FXR-dependent and -independent interaction of glucocorticoids with the regulatory pathways involved in the control of bile acid handling by the liver.
Ruben Rosales; Maria J Monte; Alba G Blazquez; Oscar Briz; Jose J G Marin
ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds.
Elisa Herraez; Jose J G Marin; Marta R Romero; Maria A Serrano; Javier Vaquero; Ester Gonzalez-Sanchez; Oscar Briz
Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.

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All Publications

2013: R Rosales; Fermin Sanchez de Medina; J Vaquero; O Martinez-Augustin; Maria J Monte; P Requena; Marta R Romero; Jose J G Marin
FXR-dependent and -independent interaction of glucocorticoids with the regulatory pathways involved in the control of bile acid handling by the liver.
Biochemical pharmacology 2013;85(6):829-38.
2012: Ruben Rosales; Maria J Monte; Alba G Blazquez; Oscar Briz; Jose J G Marin
ABCC2 is involved in the hepatocyte perinuclear barrier for small organic compounds.
Biochemical pharmacology 2012;84(12):1651-9.
2012: Elisa Herraez; Jose J G Marin; Marta R Romero; Maria A Serrano; Javier Vaquero; Ester Gonzalez-Sanchez; Oscar Briz
Cisplatin-induced chemoresistance in colon cancer cells involves FXR-dependent and FXR-independent up-regulation of ABC proteins.
Molecular pharmaceutics 2012;9(9):2565-76.
2012: P Martinez-Becerra; L Muñoz-Bellvis; M Pastor-Anglada; Marta R Romero; B Sangro; Maria A Serrano; J Vaquero; L Alvarez; C Anadon; N Grañé-Boladeras; E Lozano; Rocio I R Macias; Jose J G Marin
No correlation between the expression of FXR and genes involved in multidrug resistance phenotype of primary liver tumors.
Molecular pharmaceutics 2012;9(6):1693-704.
2012: Jose J G Marin; Olga Martinez-Augustin; Rosario Del Moral-Avila; Marta R Romero; Fermin Sanchez de Medina; Luis Bujanda; Beatriz Castaño; Oscar Briz
Chemoprevention, chemotherapy, and chemoresistance in colorectal cancer.
Drug metabolism reviews 2012;44(2):148-72.
2012: Alba G Blazquez; Oscar Briz; Doris Cassio; Rocio I R Macias; Maria J Monte; Marta R Romero; Ruben Rosales; Javier Vaquero; Jose J G Marin
Characterization of the role of ABCG2 as a bile acid transporter in liver and placenta.
Molecular pharmacology 2012;81(2):273-83.
2012: Maite G Fernández-Barrena; M Ujue Latasa; Jose J G Marin; Maria J Monte; Jesus Prieto; Carlos M Rodriguez-Ortigosa; Iker Uriarte; Eva Vicente; Carmen Berasain; Haisul C Y Chang; Ronald Oude Elferink; Matias A Ávila
Lack of Abcc3 expression impairs bile-acid induced liver growth and delays hepatic regeneration after partial hepatectomy in mice.
Journal of hepatology 2012;56(2):367-73.
2011: Rocio I R Macias; Susana Cuesta de Juan; Francisco Gonzalez-San Martin; Carlos Hierro; Felipe Jimenez; Jose J G Marin
Hepatic expression of sodium-dependent vitamin C transporters: ontogeny, subtissular distribution and effect of chronic liver diseases.
The British journal of nutrition 2011;106(12):1814-25.
2011: Raúl González; Pedro López-Cillero; Jose J G Marin; Javier Briceño; Adolfo Cruz; Manuel De la Mata; Gustavo Ferrín; Miguel A Gómez; Javier Padillo; Sebastian Rufian Peña; Jordi Muntané
Cytoprotective properties of rifampicin are related to the regulation of detoxification system and bile acid transporter expression during hepatocellular injury induced by hydrophobic bile acids.
Journal of hepato-biliary-pancreatic sciences 2011;18(5):740-50.
2011: Raúl González; Pedro López-Cillero; Jose J G Marin; Antonio Martínez-Ruiz; Manuel De la Mata; Javier Briceño; Adolfo Cruz; Rubén Fernández-Rodríguez; Gustavo Ferrín; Miguel A Gómez; Sebastián Rufián; Jordi Muntané
Nitric oxide mimics transcriptional and post-translational regulation during α-tocopherol cytoprotection against glycochenodeoxycholate-induced cell death in hepatocytes.
Journal of hepatology 2011;55(1):133-44.
2011: Nikolaj S Nytofte; Maria A Serrano; Maria J Monte; Ester Gonzalez-Sanchez; Zeynep Tumer; Karin Ladefoged; Oscar Briz; Jose J G Marin
A homozygous nonsense mutation (c.214C->A) in the biliverdin reductase alpha gene (BLVRA) results in accumulation of biliverdin during episodes of cholestasis.
Journal of medical genetics 2011;48(4):219-25.
2011: Pablo Martinez-Becerra; Oscar Briz; Marta R Romero; Rocio I R Macias; Maria J Perez; Carlos Sancho-Mateo; Maria P Lostao; Jose M Fernandez-Abalos; Jose J G Marin
Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.
Molecular pharmacology 2011;79(3):596-607.
2011: Carolina Ghanem; Agostina Arias; Analia Novak; Griselda Delli Carpini; Silvina S M Villanueva; Alba G Blazquez; Jose J G Marin; Aldo D Mottino; Modesto C Rubio
Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell line.
Biochemical pharmacology 2011;81(2):244-50.
2010: Jose J G Marin; B Castaño; A G Blazquez; R Rosales; Thomas Efferth; Maria J Monte
Strategies for overcoming chemotherapy resistance in enterohepatic tumours.
Current molecular medicine 2010;10(5):467-85.
2010: Shadi Abu-Hayyeh; Pablo Martinez-Becerra; Siti H Sheikh Abdul Kadir; Clare Selden; Marta R Romero; Myrddin Rees; Hanns-Ulrich Marschall; Jose J G Marin; Catherine Williamson
Inhibition of Na+-taurocholate Co-transporting polypeptide-mediated bile acid transport by cholestatic sulfated progesterone metabolites.
The Journal of biological chemistry 2010;285(22):16504-12.
2009: Jose J G Marin; Marta R Romero; P Martinez-Becerra; E Herraez; Oscar Briz
Overview of the molecular bases of resistance to chemotherapy in liver and gastrointestinal tumours.
Current molecular medicine 2009;9(9):1108-29.
2009: Elisa Herraez; Rocio I R Macias; Jose Vazquez-Tato; Marta Vicens; Maria J Monte; Jose J G Marin
In vitro inhibition of OATP-mediated uptake of phalloidin using bile acid derivatives.
Toxicology and applied pharmacology 2009;239(1):13-20.
2009: Elisa Herraez; Rocio I R Macias; Jose Vazquez-Tato; Carlos Hierro; Maria J Monte; Jose J G Marin
Protective effect of bile acid derivatives in phalloidin-induced rat liver toxicity.
Toxicology and applied pharmacology 2009;239(1):21-8.
2009: Jose J G Marin; Marta R Romero; Alba G Blazquez; Elisa Herraez; Emma Keck; Oscar Briz
Importance and limitations of chemotherapy among the available treatments for gastrointestinal tumours.
Anti-cancer agents in medicinal chemistry 2009;9(2):162-84.
2009: Jose J G Marin; Oscar Briz; Maria J Perez; Marta R Romero; Maria J Monte
Hepatobiliary transporters in the pharmacology and toxicology of anticancer drugs.
Frontiers in bioscience : a journal and virtual library 2009;14():4257-80.
2008: Maria J Perez; Beatriz Castaño; Silvia Jimenez; Maria A Serrano; Jose M Gonzalez-Buitrago; Jose J G Marin
Role of vitamin C transporters and biliverdin reductase in the dual pro-oxidant and anti-oxidant effect of biliary compounds on the placental-fetal unit in cholestasis during pregnancy.
Toxicology and applied pharmacology 2008;232(2):327-36.
2008: Thomas Efferth; Marta R Romero; Dana G Wolf; Thomas Stamminger; Jose J G Marin; Manfred Marschall
The antiviral activities of artemisinin and artesunate.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(6):804-11.
2008: Maria J Monte; Ruben Rosales; Rocio I R Macias; Valeria Iannota; Almudena Martinez-Fernandez; Marta R Romero; Alan Hofmann; Jose J G Marin
Cytosol-nucleus traffic and colocalization with FXR of conjugated bile acids in rat hepatocytes.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(1):G54-G62.
2008: Jose J G Marin; Rocio I R Macias; Oscar Briz; Maria J Perez; Alba G Blazquez; Marco Arrese; Maria A Serrano
Molecular bases of the fetal liver-placenta-maternal liver excretory pathway for cholephilic compounds.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(4):435-54.
2008: Marco Arrese; Rocio I R Macias; Oscar Briz; Maria J Perez; Jose J G Marin
Molecular pathogenesis of intrahepatic cholestasis of pregnancy.
Expert reviews in molecular medicine 2008;10():e9.
2007: Doris Cassio; Rocio I R Macias; Brigitte Grosse; Jose J G Marin; Maria J Monte
Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3-1 and Can 10.
Cell and tissue research 2007;330(3):447-60.
2007: Maria J Perez; Beatriz Castaño; Jose M Gonzalez-Buitrago; Jose J G Marin
Multiple protective effects of melatonin against maternal cholestasis-induced oxidative stress and apoptosis in the rat fetal liver-placenta-maternal liver trio.
Journal of pineal research 2007;43(2):130-9.
2007: Marta R Romero; Maria A Serrano; Thomas Efferth; Marcelino Alvarez; Jose J G Marin
Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication.
Planta medica 2007;73(6):552-8.
2007: Susana Cuesta de Juan; Maria J Monte; Rocio I R Macias; Valérie Wauthier; Pedro Buc Calderon; Jose J G Marin
Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.
Journal of lipid research 2007;48(6):1362-70.
2007: Marta Vallejo; Maria A Castro; Manuel Medarde; Rocio I R Macias; Marta R Romero; Mohamad Y El-Mir; Maria J Monte; Oscar Briz; Maria A Serrano; Jose J G Marin
Novel bile acid derivatives (BANBs) with cytostatic activity obtained by conjugation of their side chain with nitrogenated bases.
Biochemical pharmacology 2007;73(9):1394-404.
2007: Oscar Briz; Doris Cassio; Alba G Blazquez; Brigitte Grosse; Maria A Serrano; Jose J G Marin
Characterization of WIF-B9/R cells as an in vitro model with hepatocyte-like polarity and enhanced expression of canalicular ABC transporters involved in phase III of hepatic detoxification.
Toxicology 2007;232(1-2):24-36.
2007: Marta Vicens; Manuel Medarde; Rocio I R Macias; Monica G Larena; Antonio Villafaina; Maria A Serrano; Jose J G Marin
Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake.
Bioorganic & medicinal chemistry 2007;15(6):2359-67.
2007: Marta Vicens; Rocio I R Macias; Oscar Briz; Alfonso Rodriguez; Mohamad Y El-Mir; Manuel Medarde; Jose J G Marin
Inhibition of the intestinal absorption of bile acids using cationic derivatives: mechanism and repercussions.
Biochemical pharmacology 2007;73(3):394-404.
2007: Maria A Serrano; Rocio I R Macias; Oscar Briz; Maria J Monte; A G Blazquez; C Williamson; R Kubitz; Jose J G Marin
Expression in human trophoblast and choriocarcinoma cell lines, BeWo, Jeg-3 and JAr of genes involved in the hepatobiliary-like excretory function of the placenta.
Placenta 2007;28(2-3):107-17.
2006: Oscar Briz; Marta R Romero; Pablo Martinez-Becerra; Rocio I R Macias; Maria J Perez; Felipe Jimenez; Francisco G San Martin; Jose J G Marin
OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes?
The Journal of biological chemistry 2006;281(41):30326-35.
2006: Marta R Romero; Maria A Serrano; Marta Vallejo; Thomas Efferth; Marcelino Alvarez; Jose J G Marin
Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV).
Planta medica 2006;72(13):1169-74.
2006: Maria R Ballestero; Maria J Monte; Oscar Briz; Felipe Jimenez; Francisco Gonzalez-San Martin; Jose J G Marin
Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps.
Biochemical pharmacology 2006;72(6):729-38.
2006: Maria J Perez; Elena Velasco; Maria J Monte; Jose M Gonzalez-Buitrago; Jose J G Marin
Maternal ethanol consumption during pregnancy enhances bile acid-induced oxidative stress and apoptosis in fetal rat liver.
Toxicology 2006;225(2-3):183-94.
2006: Rocio I R Macias; S Jimenez; Maria A Serrano; Maria J Monte; Jose J G Marin
Effect of maternal cholestasis and treatment with ursodeoxycholic acid on the expression of genes involved in the secretion of biliary lipids by the neonatal rat liver.
Life sciences 2006;79(10):1014-9.
2006: Marta Vallejo; Oscar Briz; Maria A Serrano; Maria J Monte; Jose J G Marin
Potential role of trans-inhibition of the bile salt export pump by progesterone metabolites in the etiopathogenesis of intrahepatic cholestasis of pregnancy.
Journal of hepatology 2006;44(6):1150-7.
2006: Oscar Briz; Rocio I R Macias; Maria J Perez; Maria A Serrano; Jose J G Marin
Excretion of fetal biliverdin by the rat placenta-maternal liver tandem.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(3):R749-56.
2006: Maria J Perez; Rocio I R Macias; Jose J G Marin
Maternal cholestasis induces placental oxidative stress and apoptosis. Protective effect of ursodeoxycholic acid.
Placenta 2006;27(1):34-41.
2005: Marta R Romero; Thomas Efferth; Maria A Serrano; Beatriz Castaño; Rocio I R Macias; Oscar Briz; Jose J G Marin
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system.
Antiviral research 2005;68(2):75-83.
2005: Maria J Monte; Maria R Ballestero; Oscar Briz; Maria J Perez; Jose J G Marin
Proapoptotic effect on normal and tumor intestinal cells of cytostatic drugs with enterohepatic organotropism.
The Journal of pharmacology and experimental therapeutics 2005;315(1):24-35.
2005: Maria J Perez; Rocio I R Macias; Cristina Duran; Maria J Monte; Jose M Gonzalez-Buitrago; Jose J G Marin
Oxidative stress and apoptosis in fetal rat liver induced by maternal cholestasis. Protective effect of ursodeoxycholic acid.
Journal of hepatology 2005;43(2):324-32.
2005: Maria J Monte; Maria Fernandez-Tagarro; Rocio I R Macias; Felipe Jimenez; Francisco Gonzalez-San Martin; Jose J G Marin
Changes in the expression of genes related to bile acid synthesis and transport by the rat liver during hepatocarcinogenesis.
Clinical science (London, England : 1979) 2005;109(2):199-207.
2005: Maria J Monte; Maria Fernandez-Tagarro; Jose J G Marin
Transient changes in the expression pattern of key enzymes for bile acid synthesis during rat liver regeneration.
Biochimica et biophysica acta 2005;1734(2):127-35.
2005: Francisco Jorquera; Maria J Monte; Jose Guerra; Sonia Sanchez-Campos; Jose A Merayo; Jose L Olcóz; Javier González-Gallego; Jose J G Marin
Usefulness of combined measurement of serum bile acids and ferritin as additional prognostic markers to predict failure to reach sustained response to antiviral treatment in chronic hepatitis C.
Journal of gastroenterology and hepatology 2005;20(4):547-54.
2005: Rocio I R Macias; Maria A Serrano; Maria J Monte; Silvia Jimenez; Belen Hernandez; Jose J G Marin
Long-term effect of treating pregnant rats with ursodeoxycholic acid on the congenital impairment of bile secretion induced in the pups by maternal cholestasis.
The Journal of pharmacology and experimental therapeutics 2005;312(2):751-8.
2004: Marie V St Pierre; Thomas Stallmach; A Freimoser Grundschober; J-F Dufour; Maria A Serrano; Jose J G Marin; Y Sugiyama; Peter J Meier Abt
Temporal expression profiles of organic anion transport proteins in placenta and fetal liver of the rat.
American journal of physiology. Regulatory, integrative and comparative physiology 2004;287(6):R1505-16.
2004: Jose J G Marin; Oscar Briz; Maria A Serrano
A review on the molecular mechanisms involved in the placental barrier for drugs.
Current drug delivery 2004;1(3):275-89.
2003: Maria J Monte; Gloria R Villanueva; Rocio I R Macias; David J Vazquez; Marta Toledo; Mercedes Dominguez; Jose J G Marin
Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring.
Clinical science (London, England : 1979) 2003;105(3):347-53.
2003: Jose J G Marin; Rocio I R Macias; Maria A Serrano
The hepatobiliary-like excretory function of the placenta. A review.
Placenta 2003;24(5):431-8.
2003: Oscar Briz; Rocio I R Macias; Maria A Serrano; Javier González-Gallego; JE Bayón; Jose J G Marin
Excretion of foetal bilirubin by the rat placenta-maternal liver tandem.
Placenta 2003;24(5):462-72.
2003: Maria A Serrano; Rocio I R Macias; Marta Vallejo; Oscar Briz; A Bravo; Maria J Pascual; Marie V St Pierre; Bruno Stieger; Peter J Meier Abt; Jose J G Marin
Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway.
The Journal of pharmacology and experimental therapeutics 2003;305(2):515-24.
2003: Oscar Briz; Maria A Serrano; Rocio I R Macias; Javier González-Gallego; Jose J G Marin
Role of organic anion-transporting polypeptides, OATP-A, OATP-C and OATP-8, in the human placenta-maternal liver tandem excretory pathway for foetal bilirubin.
The Biochemical journal 2003;371(Pt 3):897-905.
2003: Jose J G Marin; Daniel Mangas; Maria C Martinez-Diez; Mohamad Y El-Mir; Oscar Briz; Maria A Serrano
Sensitivity of bile acid transport by organic anion-transporting polypeptides to intracellular pH.
Biochimica et biophysica acta 2003;1611(1-2):249-57.
2003: Oscar Briz; Rocio I R Macias; Marta Vallejo; Augusto Silva; Maria A Serrano; Jose J G Marin
Usefulness of liposomes loaded with cytostatic bile acid derivatives to circumvent chemotherapy resistance of enterohepatic tumors.
Molecular pharmacology 2003;63(3):742-50.
2003: Maria E Mendoza; Maria J Monte; Maria A Serrano; Marçal Pastor-Anglada; Bruno Stieger; Peter J Meier Abt; Manuel Medarde; Jose J G Marin
Physiological characteristics of allo-cholic acid.
Journal of lipid research 2003;44(1):84-92.
2002: Marta R Romero; Maria C Martinez-Diez; Monica G Larena; Rocio I R Macias; Mercedes Dominguez; Carmelo Garcia-Monzon; Maria A Serrano; Jose J G Marin
Evidence for dual effects of DNA-reactive bile acid derivatives (Bamets) on hepatitis B virus life cycle in an in vitro replicative system.
Antiviral chemistry & chemotherapy 2002;13(6):371-80.
2002: Felipe Jimenez; Maria J Monte; Mohamad Y El-Mir; Maria J Pascual; Jose J G Marin
Chronic renal failure-induced changes in serum and urine bile acid profiles.
Digestive diseases and sciences 2002;47(11):2398-406.
2002: Monica G Larena; Maria C Martinez-Diez; Rocio I R Macias; Maria F Dominguez; Maria A Serrano; Jose J G Marin
Relationship between tumor cell load and sensitivity to the cytostatic effect of two novel platinum-bile acid complexes, Bamet-D3 and Bamet-UD2.
Journal of drug targeting 2002;10(5):397-404.
2002: Maria A Serrano; JE Bayón; Lorella Pascolo; C Tiribelli; J Donald Ostrow; Javier González-Gallego; Jose J G Marin
Evidence for carrier-mediated transport of unconjugated bilirubin across plasma membrane vesicles from human placental trophoblast.
Placenta 2002;23(7):527-35.
2002: Maria J Pascual; Maria A Serrano; Mohamad Y El-Mir; Rocio I R Macias; Felipe Jiménez; Jose J G Marin
Relationship between asymptomatic hypercholanaemia of pregnancy and progesterone metabolism.
Clinical science (London, England : 1979) 2002;102(5):587-93.
2002: Maria J Monte; Maria C Martinez-Diez; Mohamad Y El-Mir; Maria E Mendoza; Pilar Bravo; Oriol Bachs; Jose J G Marin
Changes in the pool of bile acids in hepatocyte nuclei during rat liver regeneration.
Journal of hepatology 2002;36(4):534-42.
2002: Oscar Briz; Maria A Serrano; Noemi Rebollo; Bruno Hagenbuch; Peter J Meier Abt; Hermann Koepsell; Jose J G Marin
Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.
Molecular pharmacology 2002;61(4):853-60.
2002: Maria E Mendoza; Maria J Monte; Mohamad Y El-Mir; MD Badia; Jose J G Marin
Changes in the pattern of bile acids in the nuclei of rat liver cells during hepatocarcinogenesis.
Clinical science (London, England : 1979) 2002;102(2):143-50.
2001: Maria J Monte; MD Badia; Maria A Serrano; M P Sacristan; Doris Cassio; Jose J G Marin
Predominance of human versus rat phenotype in the metabolic pathways for bile acid synthesis by hybrid WIF-B9 cells.
Biochimica et biophysica acta 2001;1534(1):45-55.
2001: Maria J Pascual; Rocio I R Macias; J Garcia-Del-Pozo; Maria A Serrano; Jose J G Marin
Enhanced efficiency of the placental barrier to cisplatin through binding to glycocholic acid.
Anticancer research 2001;21(4A):2703-7.
2001: Monica G Larena; Maria C Martinez-Diez; Maria J Monte; Maria F Dominguez; Maria J Pascual; Jose J G Marin
Liver organotropism and biotransformation of a novel platinum-ursodeoxycholate derivative, Bamet-UD2, with enhanced antitumour activity.
Journal of drug targeting 2001;9(3):185-200.
2001: Maria F Dominguez; Rocio I R Macias; I Izco-Basurko; A de la Fuente; Maria J Pascual; Jose Maria Criado; Maria J Monte; Javier Yajeya; Jose J G Marin
Low in vivo toxicity of a novel cisplatin-ursodeoxycholic derivative (Bamet-UD2) with enhanced cytostatic activity versus liver tumors.
The Journal of pharmacology and experimental therapeutics 2001;297(3):1106-12.
2001: Mohamad Y El-Mir; MD Badia; N Luengo; Maria J Monte; Jose J G Marin
Increased levels of typically fetal bile acid species in patients with hepatocellular carcinoma.
Clinical science (London, England : 1979) 2001;100(5):499-508.
2000: Oscar Briz; Maria A Serrano; Rocio I R Macias; Jose J G Marin
Overcoming cisplatin resistance in vitro by a free and liposome-encapsulated bile acid derivative: BAMET-R2.
International journal of cancer. Journal international du cancer 2000;88(2):287-92.
2000: Marie V St Pierre; Maria A Serrano; Rocio I R Macias; U Dubs; M Hoechli; U Lauper; Peter J Meier Abt; Jose J G Marin
Expression of members of the multidrug resistance protein family in human term placenta.
American journal of physiology. Regulatory, integrative and comparative physiology 2000;279(4):R1495-503.
2000: Maria C Martinez-Diez; Monica G Larena; Maria A Serrano; Rocio I R Macias; I Izco-Basurko; Jose J G Marin
Relationship between DNA-reactivity and cytostatic effect of two novel bile acid-platinum derivatives, Bamet-UD2 and Bamet-D3.
Anticancer research 2000;20(5A):3315-21.
2000: Rocio I R Macias; Maria J Pascual; A Bravo; M P Alcalde; Monica G Larena; Marie V St Pierre; Maria A Serrano; Jose J G Marin
Effect of maternal cholestasis on bile acid transfer across the rat placenta-maternal liver tandem.
Hepatology (Baltimore, Md.) 2000;31(4):975-83.
2000: Maria C Martinez-Diez; Maria A Serrano; Maria J Monte; Jose J G Marin
Comparison of the effects of bile acids on cell viability and DNA synthesis by rat hepatocytes in primary culture.
Biochimica et biophysica acta 2000;1500(2):153-60.
2000: Maria J Monte; F Palomero; GR Sainz; M Domínguez; M Díez; Alfredo Toraño; Jose J G Marin
Bile acid secretion during rat liver carcinogenesis.
Life sciences 2000;66(12):1085-95.
1999: Julio J Criado; M C Garcia-Moreno; R R Macias; Jose J G Marin; Manuel Medarde; E Rodriguez-Fernandez
Synthesis and characterization of sodium cis-dichlorochenodeoxycholylglycinato(O,N) platinum(II)--cytostatic activity.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1999;12(3):281-8.
1999: Maria J Monte; S Dominguez; MF Palomero; Rocio I R Macias; Jose J G Marin
Further evidence of the usefulness of bile acids as molecules for shuttling cytostatic drugs toward liver tumors.
Journal of hepatology 1999;31(3):521-8.
1999: Rocio I R Macias; Mohamad Y El-Mir; Maria J Monte; Maria A Serrano; M J Garcia; Jose J G Marin
Cholephilic characteristics of a new cytostatic complex of cisplatin with glycocholate (Bamet-R2).
Journal of controlled release : official journal of the Controlled Release Society 1999;57(2):161-9.
1998: Jose J G Marin; Rocio I R Macias; Julio J Criado; A Bueno; Maria J Monte; Maria A Serrano
DNA interaction and cytostatic activity of the new liver organotropic complex of cisplatin with glycocholic acid: Bamet-R2.
International journal of cancer. Journal international du cancer 1998;78(3):346-52.
1998: MC Herrera; MF Palomero; Rocio I R Macias; Maria A Serrano; Jose J G Marin
Comparison of the effects of bischolylglycinatechloro-platinum(II) versus cisplatin on liver regeneration after partial hepatectomy.
Anticancer research 1998;18(5A):3555-63.
1998: Rocio I R Macias; Maria J Monte; Mohamad Y El-Mir; Gloria R Villanueva; Jose J G Marin
Transport and biotransformation of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate (Bamet-R2) by the rat liver.
Journal of lipid research 1998;39(9):1792-8.
1998: Jose J G Marin; MF Palomero; MC Herrera; Rocio I R Macias; Julio J Criado; Maria A Serrano
In vitro cytostatic activity and DNA-interaction of the new liver organotropic complex chloro-bis-cholylglycinate-platinum (II).
Anticancer research 1998;18(3A):1641-7.
1998: Maria A Serrano; Dora Brites; Monica G Larena; Maria J Monte; M P Bravo; N Oliveira; Jose J G Marin
Beneficial effect of ursodeoxycholic acid on alterations induced by cholestasis of pregnancy in bile acid transport across the human placenta.
Journal of hepatology 1998;28(5):829-39.
1998: Mohamad Y El-Mir; Maria A Serrano; Rocio I R Macias; Maria F Dominguez; Maria J Monte; Jose J G Marin
In vitro test to determine the effect of cytostatic drugs on co-cultured rat hepatocytes and hepatoma cells.
International journal of experimental pathology 1998;79(2):109-15.
1998: Jose J G Marin; MC Herrera; MF Palomero; Rocio I R Macias; Maria J Monte; Mohamad Y El-Mir; Gloria R Villanueva
Rat liver transport and biotransformation of a cytostatic complex of bis-cholylglycinate and platinum (II).
Journal of hepatology 1998;28(3):417-25.
1998: Oscar Briz; Mohamad Y El-Mir; Pilar Bravo; Gloria R Villanueva; Jose J G Marin
Fetal excretion of the fluorescent bile acid derivative cholylglycylamido-fluorescein (FITC-GC) by the rat placenta-maternal liver tandem.
Placenta 1998;19(1):119-26.
1997: Maria A Serrano; Maria J Monte; Maria C Martinez-Diez; Jose J G Marin
Effect of maternal cholestasis on the kinetics of bile acid transport across the canalicular membrane of infant rat livers.
International journal of experimental pathology 1997;78(6):383-90.
1997: Maria J Monte; Mohamad Y El-Mir; GR Sainz; Pilar Bravo; Jose J G Marin
Bile acid secretion during synchronized rat liver regeneration.
Biochimica et biophysica acta 1997;1362(1):56-66.
1997: Mohamad Y El-Mir; Maria J Monte; Ana I Morales; Miguel Arevalo; Maria A Serrano; Jose J G Marin
Effect of maternal cholestasis on biliary lipid and bile acid secretion in the infant rat.
Hepatology (Baltimore, Md.) 1997;26(3):527-36.
1997: Julio J Criado; Rocio I R Macias; Manuel Medarde; Maria J Monte; Maria A Serrano; Jose J G Marin
Synthesis and characterization of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate.
Bioconjugate chemistry 1997;8(4):453-8.
1997: Julio J Criado; MC Herrera; MF Palomero; Manuel Medarde; E Rodriguez; Jose J G Marin
Synthesis and characterization of a new bile acid and platinum(II) complex with cytostatic activity.
Journal of lipid research 1997;38(5):1022-32.
1997: GR Sainz; Maria J Monte; E R Barbero; MC Herrera; Jose J G Marin
Bile secretion by the rat liver during synchronized regeneration.
International journal of experimental pathology 1997;78(2):109-16.
1997: Gloria R Villanueva; Maria E Mendoza; Mohamad Y El-Mir; Maria J Monte; MC Herrera; Jose J G Marin
Effect of bile acids on hepatobiliary transport of cisplatin by perfused rat liver.
Pharmacology & toxicology 1997;80(3):111-7.
1996: J M Monte; E R Barbero; Gloria R Villanueva; Maria A Serrano; Jose J G Marin
Role of rate-limiting enzymes of nucleotide metabolism in taurocholate-induced DNA synthesis inhibition.
Journal of hepatology 1996;25(2):191-9.
1996: Maria J Monte; Ana I Morales; M Arevalo; I Alvaro; Rocio I R Macias; Jose J G Marin
Reversible impairment of neonatal hepatobiliary function by maternal cholestasis.
Hepatology (Baltimore, Md.) 1996;23(5):1208-17.
1996: Gloria R Villanueva; Maria J Monte; E R Barbero; Maria A Serrano; Jose J G Marin
Evidence for dual effect of bile acids on thymidine anabolism and catabolism by the regenerating rat liver.
Biochimica et biophysica acta 1996;1289(1):136-44.
1995: P Bravo; Jose J G Marin; Mark Beveridge; Donald A Novak
Reconstitution and characterization of ATP-dependent bile acid transport in human and rat placenta.
The Biochemical journal 1995;311 ( Pt 2)():479-85.
1995: Maria J Monte; T Rodriguez-Bravo; Rocio I R Macias; P Bravo; Mohamad Y El-Mir; Maria A Serrano; A Lopez-Salva; Jose J G Marin
Relationship between bile acid transplacental gradients and transport across the fetal-facing plasma membrane of the human trophoblast.
Pediatric research 1995;38(2):156-63.
1995: E R Barbero; MC Herrera; Maria J Monte; Maria A Serrano; Jose J G Marin
Role of amidation in bile acid effect on DNA synthesis by regenerating mouse liver.
The American journal of physiology 1995;268(6 Pt 1):G1051-9.
1995: G R Villaneuva; L I Sanchez-Abarca; P Bravo; Mohamad Y El-Mir; Jose J G Marin
Assessment of hepatobiliary function and placental barrier integrity in pregnant rats by combination of bromosulphophthalein and fluorescein isothiocyanate plasma disappearance tests.
International journal of experimental pathology 1995;76(3):183-90.
1995: Jose J G Marin; P Bravo; Mohamad Y El-Mir; Maria A Serrano
ATP-dependent bile acid transport across microvillous membrane of human term trophoblast.
The American journal of physiology 1995;268(4 Pt 1):G685-94.
1993: Jose J G Marin; E R Barbero; MC Herrera; Arantxa Tabernero; Maria J Monte
Bile acid-induced modifications in DNA synthesis by the regenerating perfused rat liver.
Hepatology (Baltimore, Md.) 1993;18(5):1182-92.
1993: Maria A Serrano; P Bravo; Mohamad Y El-Mir; Jose J G Marin
Influence of hydroxylation and conjugation in cross-inhibition of bile acid transport across the human trophoblast basal membrane.
Biochimica et biophysica acta 1993;1151(1):28-34.
1993: Gloria R Villanueva; Mohamad Y El-Mir; F Perez-Barriocanal; P Bravo; Jose J G Marin
Effect of insulin and glucose load on bile lactate secretion by the isolated rat liver. Role of hepatic parenchyma heterogeneity.
Biochimica et biophysica acta 1993;1158(1):8-14.
1993: P Bravo; Mohamad Y El-Mir; Maria A Serrano; R Boyd; Jose J G Marin
Interaction between cholephilic anions and bile acid transport across basal membrane of human trophoblast.
The American journal of physiology 1993;265(2 Pt 1):G242-50.
1993: Maria J Monte; M D Badia; F Palomero; Mohamad Y El-Mir; J R Alonso; Jose J G Marin
Effects of selective zonal injury on bile acid-induced bile flow in the isolated rat liver.
The American journal of physiology 1993;264(6 Pt 1):G1103-11.
1992: Nélida Eleno; C A R Boyd; Jose J G Marin
Substrate-specific differences in the rate of bile acid carrier reorientation: studies on human placental basal vesicles.
Biochimica et biophysica acta 1992;1111(1):139-41.
1992: MC Herrera; Mohamad Y El-Mir; Maria J Monte; F Perez-Barriocanal; Jose J G Marin
Further evaluation of the interrelationship between the hepatocellular transport of bile acids and endocytosed proteins.
International journal of experimental pathology 1992;73(2):203-14.
1991: Jose J G Marin; P Bravo; F Perez Barriocanal; Mohamad Y El-Mir; Gloria R Villanueva
Hyperglycemia-induced cholestasis in the isolated perfused rat liver.
Hepatology (Baltimore, Md.) 1991;14(1):184-91.
1991: Mohamad Y El-Mir; Nélida Eleno; Maria A Serrano; P Bravo; Jose J G Marin
Bicarbonate-induced activation of taurocholate transport across the basal plasma membrane of human term trophoblast.
The American journal of physiology 1991;260(6 Pt 1):G887-94.
1990: Jose J G Marin; Maria A Serrano; Mohamad Y El-Mir; Nélida Eleno; C A Boyd
Bile acid transport by basal membrane vesicles of human term placental trophoblast.
Gastroenterology 1990;99(5):1431-8.
1990: F Perez Barriocanal; Jose J G Marin; M Dumont; S Erlinger
Influence of backward perfusion on ursodeoxycholate-induced choleresis in isolated in situ rat liver.
Journal of hepatology 1990;11(2):165-71.
1990: Gloria R Villanueva; M Herreros; F Perez-Barriocanal; J P Bolaños; P Bravo; Jose J G Marin
Enhancement of bile acid-induced biliary lipid secretion by streptozotocin in rats: role of insulin deficiency.
The Journal of laboratory and clinical medicine 1990;115(4):441-8.
1990: Jose J G Marin; M Herreros; Gloria R Villanueva; F Perez-Barriocanal; Mohamad Y El-Mir; José M Medina
Effect of streptozotocin-induced diabetes on sex differences in biliary lipid secretion in the rat.
Biochimica et biophysica acta 1990;1043(1):106-12.
1990: F Perez-Barriocanal; J C Perez-Antona; P Regueiro; Gloria R Villanueva; Jose J G Marin
Biliary lipid secretion during the prereplicative phase of rat liver regeneration.
Journal of experimental pathology (Oxford, England) 1990;71(1):63-8.
1990: Gloria R Villanueva; M Herreros; F Perez-Barriocanal; E Fernandez; Jose J G Marin
Effect of acute insulin administration on biliary lipid secretion by the diabetic rat.
Journal of experimental pathology (Oxford, England) 1990;71(1):89-94.
1989: F Perez-Barriocanal; J G Redondo-Torres; Gloria R Villanueva; E Arteche; M M Berenson; Jose J G Marin
Protoporphyrin IX-induced impairment of biliary lipid secretion in the rat.
Clinical science (London, England : 1979) 1989;77(5):473-8.
1987: M M Berenson; Jose J G Marin; R Larsen; D Avner
Effect of bile acids on hepatic protoporphyrin metabolism in perfused rat liver.
Gastroenterology 1987;93(5):1086-93.