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Bruce Markham

Research Profile

Chemicals & Drugs

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Myocardium

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Publications

TOP 3
Yan-Shan Dai; Peter Cserjesi; Bruce E Markham; Jeffery D Molkentin
The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism.
Qiangrong Liang; R J Wiese; Orlando F Bueno; Yan-Shan Dai; Bruce E Markham; Jeffery D Molkentin
The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes.
Yan-Shan Dai; Bruce E Markham
p300 Functions as a coactivator of transcription factor GATA-4.

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All Publications

2002: Yan-Shan Dai; Peter Cserjesi; Bruce E Markham; Jeffery D Molkentin
The transcription factors GATA4 and dHAND physically interact to synergistically activate cardiac gene expression through a p300-dependent mechanism.
The Journal of biological chemistry 2002;277(27):24390-8.
2001: Qiangrong Liang; R J Wiese; Orlando F Bueno; Yan-Shan Dai; Bruce E Markham; Jeffery D Molkentin
The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes.
Molecular and cellular biology 2001;21(21):7460-9.
2001: Yan-Shan Dai; Bruce E Markham
p300 Functions as a coactivator of transcription factor GATA-4.
The Journal of biological chemistry 2001;276(40):37178-85.
2001: Qiangrong Liang; Leon J De Windt; SA Witt; T R Kimball; Bruce E Markham; Jeffery D Molkentin
The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo.
The Journal of biological chemistry 2001;276(32):30245-53.
1998: Youngsook Lee; Tetsuo Shioi; Hideko Kasahara; SM Jobe; R J Wiese; Bruce E Markham; Seigo Izumo
The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression.
Molecular and cellular biology 1998;18(6):3120-9.
1997: K Hasegawa; S J Lee; SM Jobe; Bruce E Markham; Richard N Kitsis
cis-Acting sequences that mediate induction of beta-myosin heavy chain gene expression during left ventricular hypertrophy due to aortic constriction.
Circulation 1997;96(11):3943-53.
1997: T C Herzig; SM Jobe; H Aoki; Jeffery D Molkentin; A W Cowley; Seigo Izumo; Bruce E Markham
Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7543-8.
1996: J D Molkentin; S M Jobe; Bruce E Markham
Alpha-myosin heavy chain gene regulation: delineation and characterization of the cardiac muscle-specific enhancer and muscle-specific promoter.
Journal of molecular and cellular cardiology 1996;28(6):1211-25.
1994: J D Molkentin; Bruce E Markham
An M-CAT binding factor and an RSRF-related A-rich binding factor positively regulate expression of the alpha-cardiac myosin heavy-chain gene in vivo.
Molecular and cellular biology 1994;14(8):5056-65.
1994: J D Molkentin; Dhan V Kalvakolanu; Bruce E Markham
Transcription factor GATA-4 regulates cardiac muscle-specific expression of the alpha-myosin heavy-chain gene.
Molecular and cellular biology 1994;14(7):4947-57.
1993: J D Molkentin; Bruce E Markham
Myocyte-specific enhancer-binding factor (MEF-2) regulates alpha-cardiac myosin heavy chain gene expression in vitro and in vivo.
The Journal of biological chemistry 1993;268(26):19512-20.
1993: Richard J Roman; Y H Ma; Bruce Harold Frohlich; Bruce E Markham
Clofibrate prevents the development of hypertension in Dahl salt-sensitive rats.
Hypertension 1993;21(6 Pt 2):985-8.
1993: J D Molkentin; R S Brogan; S M Jobe; Bruce E Markham
Expression of the alpha-myosin heavy chain gene in the heart is regulated in part by an E-box-dependent mechanism.
The Journal of biological chemistry 1993;268(4):2602-9.