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Naziha Marrakchi

Research Profile

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Publications

TOP 3
Raoudha Zouari-Kessentini; Najet Srairi-Abid; Amine Bazaa; Mohamed El Ayeb; Jose Luis; Naziha Marrakchi
Antitumoral potential of Tunisian snake venoms secreted phospholipases A2.
Maram Morjen; Houcemeddine Othman; Libia Sanz; Najet Srairi-Abid; Raoudha Zouari-Kessentini; Amine Bazaa; Juan José Calvete; Mohamed El Ayeb; Olfa Kallech-Ziri; José Luis; Kamel Mabrouk; Naziha Marrakchi
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells.
Jed Jebali; José Luis; Naziha Marrakchi; Sylvie Mathieu; Maram Morjen; Amine Bazaa; Mohamed El Ayeb; Ali Gargouri; Charlotte Jeanneau; Assou El-Battari
Expression of a functional recombinant C-type lectin-like protein lebecetin in the human embryonic kidney cells.

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All Publications

2013: Raoudha Zouari-Kessentini; Najet Srairi-Abid; Amine Bazaa; Mohamed El Ayeb; Jose Luis; Naziha Marrakchi
Antitumoral potential of Tunisian snake venoms secreted phospholipases A2.
BioMed research international 2013;2013():391389.
2013: Maram Morjen; Houcemeddine Othman; Libia Sanz; Najet Srairi-Abid; Raoudha Zouari-Kessentini; Amine Bazaa; Juan José Calvete; Mohamed El Ayeb; Olfa Kallech-Ziri; José Luis; Kamel Mabrouk; Naziha Marrakchi
PIVL, a new serine protease inhibitor from Macrovipera lebetina transmediterranea venom, impairs motility of human glioblastoma cells.
Matrix biology : journal of the International Society for Matrix Biology 2013;32(1):52-62.
2012: Jed Jebali; José Luis; Naziha Marrakchi; Sylvie Mathieu; Maram Morjen; Amine Bazaa; Mohamed El Ayeb; Ali Gargouri; Charlotte Jeanneau; Assou El-Battari
Expression of a functional recombinant C-type lectin-like protein lebecetin in the human embryonic kidney cells.
Biotechnology progress 2012;28(6):1560-5.
2012: Yosra Ayed; Manel Bousabbeh; Hazem Ben Mabrouk; Naziha Marrakchi; Maram Morjen; Hassen Bacha
Impairment of the cell-to-matrix adhesion and cytotoxicity induced by the Mediterranean jellyfish Pelagia noctiluca venom and its fractions in cultured glioblastoma cells.
Lipids in health and disease 2012;11():84.
2011: J Jebali; José Luis; S Mathieu; Amine Bazaa; Mohamed El Ayeb; Assou El-Battari; C Jeanneau; Naziha Marrakchi
[Selectins as adhesion molecules and potential therapeutic target].
Archives de l'Institut Pasteur de Tunis 2011;88(1-4):3-18.
2010: Raoudha Kessentini-Zouari; Jed Jebali; Salma Taboubi; Najet Srairi-Abid; Maram Morjen; Olfa Kallech-Ziri; Laboratoire Biochimie et Genie Enzymatique des Lipases; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi; José Luis
CC-PLA2-1 and CC-PLA2-2, two Cerastes cerastes venom-derived phospholipases A2, inhibit angiogenesis both in vitro and in vivo.
Laboratory investigation; a journal of technical methods and pathology 2010;90(4):510-9.
2010: Inès Limam; Amine Bazaa; Najet Srairi-Abid; Salma Taboubi; Jed Jebali; Raoudha Zouari-Kessentini; Olfa Kallech-Ziri; Hafedh Mejdoub; Asma Hammami; Mohamed El Ayeb; José Luis; Naziha Marrakchi
Leberagin-C, A disintegrin-like/cysteine-rich protein from Macrovipera lebetina transmediterranea venom, inhibits alphavbeta3 integrin-mediated cell adhesion.
Matrix biology : journal of the International Society for Matrix Biology 2010;29(2):117-26.
2010: I Limam; Mohamed El Ayeb; Naziha Marrakchi
[Snake venom metalloproteinases: structure, biosynthesis and function(s)].
Archives de l'Institut Pasteur de Tunis 2010;87(1-2):3-15.
2010: Amine Bazaa; Eddy Pasquier; Céline Defilles; Ines Limam; Raoudha Kessentini-Zouari; Olfa Kallech-Ziri; Assou El-Battari; Diane Braguer; Mohamed El Ayeb; Naziha Marrakchi; José Luis
MVL-PLA2, a snake venom phospholipase A2, inhibits angiogenesis through an increase in microtubule dynamics and disorganization of focal adhesions.
PloS one 2010;5(4):e10124.
2009: Amine Bazaa; José Luis; Najet Srairi-Abid; Olfa Kallech-Ziri; Raoudha Kessentini-Zouari; Céline Defilles; Jean-Claude Lissitzky; Mohamed El Ayeb; Naziha Marrakchi
MVL-PLA2, a phospholipase A2 from Macrovipera lebetina transmediterranea venom, inhibits tumor cells adhesion and migration.
Matrix biology : journal of the International Society for Matrix Biology 2009;28(4):188-93.
2009: Raoudha Zouari-Kessentini; José Luis; Aida Karray; Olfa Kallech-Ziri; Najet Srairi-Abid; Amine Bazaa; Erwann Loret; Laboratoire Biochimie et Genie Enzymatique des Lipases; Mohamed El Ayeb; Naziha Marrakchi
Two purified and characterized phospholipases A2 from Cerastes cerastes venom, that inhibit cancerous cell adhesion and migration.
Toxicon : official journal of the International Society on Toxinology 2009;53(4):444-53.
2009: Jed Jebali; Amine Bazaa; Sameh Sarray; Khemais Benhaj; Anis Karboul; Mohamed El Ayeb; Naziha Marrakchi; Ali Gargouri
C-type lectin protein isoforms of Macrovipera lebetina: cDNA cloning and genetic diversity.
Toxicon : official journal of the International Society on Toxinology 2009;53(2):228-37.
2008: Sameh Sarray; José Luis; Mohamed El Ayeb; Naziha Marrakchi
[Snake venoms C-type lectins and their receptors on platelets and cancerous cells].
Archives de l'Institut Pasteur de Tunis 2008;85(1-4):69-80.
2007: Anthony Pilorget; Magali Conesa; Sameh Sarray; Jonathan Michaud-Levesque; Salma Daoud; Kwang S Kim; Michel Demeule; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi; Richard Béliveau; José Luis
Lebectin, a Macrovipera lebetina venom-derived C-type lectin, inhibits angiogenesis both in vitro and in vivo.
Journal of cellular physiology 2007;211(2):307-15.
2007: Sameh Sarray; Estelle Delamarre; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi; José Luis
Lebectin and lebecetin, two C-type lectins from snake venom, inhibit alpha5beta1 and alphaV-containing integrins.
Matrix biology : journal of the International Society for Matrix Biology 2007;26(4):306-13.
2007: Amine Bazaa; Paula Juárez; Naziha Marrakchi; Zakaria Bel Lasfer; Mohamed El Ayeb; Robert A Harrison; Juan J Calvete; Libia Sanz
Loss of introns along the evolutionary diversification pathway of snake venom disintegrins evidenced by sequence analysis of genomic DNA from Macrovipera lebetina transmediterranea and Echis ocellatus.
Journal of molecular evolution 2007;64(2):261-71.
2007: O Kallech-Ziri; José Luis; Mohamed El Ayeb; Naziha Marrakchi
[Snake venom disintegrins: classification and therapeutic potential].
Archives de l'Institut Pasteur de Tunis 2007;84(1-4):29-37.
2006: Libia Sanz; Amine Bazaa; Naziha Marrakchi; Alicia Pérez; Mehdi Chenik; Zakaria Bel Lasfer; Mohamed El Ayeb; Juan J Calvete
Molecular cloning of disintegrins from Cerastes vipera and Macrovipera lebetina transmediterranea venom gland cDNA libraries: insight into the evolution of the snake venom integrin-inhibition system.
The Biochemical journal 2006;395(2):385-92.
2005: Amine Bazaa; Naziha Marrakchi; Mohamed El Ayeb; Libia Sanz; Juan J Calvete
Snake venomics: comparative analysis of the venom proteomes of the Tunisian snakes Cerastes cerastes, Cerastes vipera and Macrovipera lebetina.
Proteomics 2005;5(16):4223-35.
2004: Sameh Sarray; Virginie Berthet; Juan J Calvete; Jeannine Secchi; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi; José Luis
Lebectin, a novel C-type lectin from Macrovipera lebetina venom, inhibits integrin-mediated adhesion, migration and invasion of human tumour cells.
Laboratory investigation; a journal of technical methods and pathology 2004;84(5):573-81.
2003: Sameh Sarray; Najet Srairi; Mohamed Hatmi; José Luis; Hechmi Louzir; Imed Regaya; Hmida Slema; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi
Lebecetin, a potent antiplatelet C-type lectin from Macrovipera lebetina venom.
Biochimica et biophysica acta 2003;1651(1-2):30-40.
2003: Hafedh Dekhil; Anne Wisner; Naziha Marrakchi; Mohamed El Ayeb; Cassian Bon; Habib Karoui
Molecular cloning and expression of a functional snake venom serine proteinase, with platelet aggregating activity, from the Cerastes cerastes viper.
Biochemistry 2003;42(36):10609-18.
2002: Naziha Marrakchi; Sameh Sarray; Jacques Marvaldi; Mohamed El Ayeb; José Luis
[Effect of Macrovipera lebetina and Cerastes cerastes venoms on adherence to integrins of cancerous cells (IGR39, HT29-D4 and IGROV1)].
Archives de l'Institut Pasteur de Tunis 2002;79(1-4):3-9.
2001: Naziha Marrakchi; Kamel Mabrouk; Imed Regaya; Sameh Sarray; Mohamed Fathallah; Hervé Rochat; Mohamed El Ayeb
Lebetin peptides: potent platelet aggregation inhibitors.
Haemostasis 2001;31(3-6):207-10.
2001: Sameh Sarray; Najet Srairi; José Luis; Jacques Marvaldi; Mohamed El Ayeb; Naziha Marrakchi
Lebecetin, a C-lectin protein from the venom of Macrovipera lebetina that inhibits platelet aggregation and adhesion of cancerous cells.
Haemostasis 2001;31(3-6):173-6.
1998: Mohamed Naceur Krifi; Naziha Marrakchi; Mohamed El Ayeb; Koussay Dellagi
Effect of some variables on the in vivo determination of scorpion and viper venom toxicities.
Biologicals : journal of the International Association of Biological Standardization 1998;26(4):277-88.
1998: Rym Barbouche; Naziha Marrakchi; Kamel Mabrouk; Mohamed Naceur Krifi; Jurphaas van Rietschoten; Emmanuel Fenouillet; Mohamed El Ayeb; Hervé Rochat
Anti-platelet activity of the peptides composing the lebetin 1 family, a new class of inhibitors of platelet aggregation.
Toxicon : official journal of the International Society on Toxinology 1998;36(12):1939-47.
1998: Naziha Marrakchi; Mohamed El Ayeb
[Thrombin-like serine proteases in Cerasted venoms (Cerasted cerastes and Cerastes vipera)].
Archives de l'Institut Pasteur de Tunis 1998;75(1-2):3-8.
1997: Naziha Marrakchi; Rym Barbouche; S Guermazi; Habib Karoui; Cassian Bon; Mohamed El Ayeb
Cerastotin, a serine protease from Cerastes cerastes venom, with platelet-aggregating and agglutinating properties.
European journal of biochemistry / FEBS 1997;247(1):121-8.
1997: Naziha Marrakchi; Rym Barbouche; S Guermazi; Cassian Bon; Mohamed El Ayeb
Procoagulant and platelet-aggregating properties of cerastocytin from Cerastes cerastes venom.
Toxicon : official journal of the International Society on Toxinology 1997;35(2):261-72.
1997: Naziha Marrakchi; S Guermazi; Mohamed El Ayeb
[The anti-platelet aggregation drugs: new approaches based on snake venom polypeptides].
Archives de l'Institut Pasteur de Tunis 1997;74(1-2):9-15.
1997: Naziha Marrakchi; Rym Barbouche; Cassian Bon; Mohamed El Ayeb
Cerastatin, a new potent inhibitor of platelet aggregation from the venom of the Tunisian viper, Cerastes cerastes.
Toxicon : official journal of the International Society on Toxinology 1997;35(1):125-35.
1996: Rym Barbouche; Naziha Marrakchi; Pascal Mansuelle; Mohamed Naceur Krifi; Emmanuel Fenouillet; Hervé Rochat; Mohamed El Ayeb
Novel anti-platelet aggregation polypeptides from Vipera lebetina venom: isolation and characterization.
FEBS letters 1996;392(1):6-10.
1995: Naziha Marrakchi; Russolina B Zingali; Habib Karoui; Cassian Bon; Mohamed El Ayeb
Cerastocytin, a new thrombin-like platelet activator from the venom of the Tunisian viper Cerastes cerastes.
Biochimica et biophysica acta 1995;1244(1):147-56.
1994: Naziha Marrakchi; Rym Barbouche; L Zinghali; Mohamed Naceur Krifi; Cassian Bon; Mohamed El Ayeb
[Biochemical and pharmacologic properties of platelet aggregants and platelet antiaggregants of viper venoms in Tunisia].
Archives de l'Institut Pasteur de Tunis 1994;71(3-4):487-91.