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Maria Lourdes Bastos

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Patrícia Silva Ferreira; Andreas Meisel; Tiago Bernandes Nogueira; Maria Lourdes Bastos; Paula Sério Branco; Félix Carvalho; Vera Marisa Costa; Eduarda Fernandes; Luísa Maria Ferreira; João Paulo Capela
Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
M S Monteiro; Maria Lourdes Bastos; M Carvalho; Paula Guedes de Pinho
Metabolomics analysis for biomarker discovery: advances and challenges.
M D Arbo; Maria Lourdes Bastos; Helena Carmo
Piperazine compounds as drugs of abuse.

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All Publications

2013: Patrícia Silva Ferreira; Andreas Meisel; Tiago Bernandes Nogueira; Maria Lourdes Bastos; Paula Sério Branco; Félix Carvalho; Vera Marisa Costa; Eduarda Fernandes; Luísa Maria Ferreira; João Paulo Capela
Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells.
Toxicology letters 2013;216(2-3):159-70.
2013: M S Monteiro; Maria Lourdes Bastos; M Carvalho; Paula Guedes de Pinho
Metabolomics analysis for biomarker discovery: advances and challenges.
Current medicinal chemistry 2013;20(2):257-71.
2012: M D Arbo; Maria Lourdes Bastos; Helena Carmo
Piperazine compounds as drugs of abuse.
Drug and alcohol dependence 2012;122(3):174-85.
2012: Pedro Nuno Moreira; Maria Teresa Baltazar; Maria Lourdes Bastos; Félix Carvalho; Paula Guedes de Pinho; Ricardo Jorge Dinis-Oliveira
Quantification of paraquat in postmortem samples by gas chromatography-ion trap mass spectrometry and review of the literature.
Biomedical chromatography : BMC 2012;26(3):338-49.
2011: M T Baltazar; Maria Lourdes Bastos; Ricardo J Dinis-Oliveira; José Duarte; Félix Carvalho
Antioxidant properties and associated mechanisms of salicylates.
Current medicinal chemistry 2011;18(21):3252-64.
2011: Maria João Valente; Rui Henrique; Vera L Costa; Carmen Jerónimo; Félix Carvalho; Maria Lourdes Bastos; Paula Guedes de Pinho; Márcia Carvalho
A rapid and simple procedure for the establishment of human normal and cancer renal primary cell cultures from surgical specimens.
PloS one 2011;6(5):e19337.
2010: Maria João Valente; Félix Carvalho; Maria Lourdes Bastos; Márcia Carvalho; Paula Guedes de Pinho
Development and validation of a gas chromatography/ion trap-mass spectrometry method for simultaneous quantification of cocaine and its metabolites benzoylecgonine and norcocaine: application to the study of cocaine metabolism in human primary cultured renal cells.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(30):3083-8.
2010: Helena Pontes; Paula Guedes de Pinho; Eduarda Fernandes; Paula Sério Branco; Luísa Maria Ferreira; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Metabolic interactions between ethanol and MDMA in primary cultured rat hepatocytes.
Toxicology 2010;270(2-3):150-7.
2010: Daniel Gomes da Silva; Paula Guedes de Pinho; Helena Pontes; Luísa Ferreira; Paula Branco; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos; Helena Carmo
Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(9-10):815-22.
2009: Carla Sousa; H Pontes; Helena Carmo; Ricardo J Dinis-Oliveira; Patrícia Valentão; Paula B Andrade; Fernando Remião; Maria Lourdes Bastos; Félix Carvalho
Water extracts of Brassica oleracea var. costata potentiate paraquat toxicity to rat hepatocytes in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(6):1131-8.
2009: João Paulo Capela; Helena Carmo; Fernando Remião; Maria Lourdes Bastos; Andreas Meisel; Félix Carvalho
Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.
Molecular neurobiology 2009;39(3):210-71.
2009: Ricardo J Dinis-Oliveira; H Pontes; Maria Lourdes Bastos; Fernando Remião; José Duarte; Félix Carvalho
An effective antidote for paraquat poisonings: the treatment with lysine acetylsalicylate.
Toxicology 2009;255(3):187-93.
2009: Vera Marisa Costa; Lusa Maria Ferreira; Paula Sério Branco; Félix Carvalho; Maria Lourdes Bastos; Rui Albuquerque Carvalho; Márcia Carvalho; Fernando Remio
Cross-functioning between the extraneuronal monoamine transporter and multidrug resistance protein 1 in the uptake of adrenaline and export of 5-(glutathion-S-yl)adrenaline in rat cardiomyocytes.
Chemical research in toxicology 2009;22(1):129-135.
2008: Helena Pontes; Carla Sousa; Renata Silva; Eduarda Fernandes; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes.
Toxicology 2008;254(1-2):42-50.
2008: Helena Pontes; José Duarte; Paula Guedes de Pinho; Maria Elisa Soares; Eduarda Fernandes; Ricardo J Dinis-Oliveira; Carla Sousa; Renata Silva; Helena Carmo; Susana Casal; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 mice.
Toxicology 2008;252(1-3):64-71.
2008: João Paulo Capela; Marion Lautenschlager; Ulrich Dirnagl; Maria Lourdes Bastos; Félix Carvalho; Andreas Meisel
5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures.
European journal of pharmacology 2008;588(2-3):232-8.
2008: Helena Pontes; Maria João Santos-Marques; Eduarda Fernandes; José Duarte; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Effect of chronic ethanol exposure on the hepatotoxicity of ecstasy in mice: an ex vivo study.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(4):910-20.
2008: Helena Pontes; Márcia Carvalho; Paula Guedes de Pinho; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Ethanol, the forgotten artifact in cell culture.
Archives of toxicology 2008;82(3):197-8.
2008: Ricardo J Dinis-Oliveira; José Duarte; A Sánchez Navarro; Fernando Remião; Maria Lourdes Bastos; Félix Carvalho
Paraquat poisonings: mechanisms of lung toxicity, clinical features, and treatment.
Critical reviews in toxicology 2008;38(1):13-71.
2007: Estela Figueiredo; Maria Elisa Soares; Paula Baptista; Marisa Castro; Maria Lourdes Bastos
Validation of an electrothermal atomization atomic absorption spectrometry method for quantification of total chromium and chromium(VI) in wild mushrooms and underlying soils.
Journal of agricultural and food chemistry 2007;55(17):7192-8.
2007: Vera Marisa Costa; Renata Silva; Luísa Maria Ferreira; Paula Sério Branco; Félix Carvalho; Maria Lourdes Bastos; Rui Albuquerque Carvalho; Márcia Carvalho; Fernando Remião
Oxidation process of adrenaline in freshly isolated rat cardiomyocytes: formation of adrenochrome, quinoproteins, and GSH adduct.
Chemical research in toxicology 2007;20(8):1183-91.
2007: João Paulo Capela; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; Andreas Meisel; Félix Carvalho
Ecstasy induces apoptosis via 5-HT(2A)-receptor stimulation in cortical neurons.
Neurotoxicology 2007;28(4):868-75.
2007: Ricardo J Dinis-Oliveira; Carla Sousa; Fernando Remião; José Duarte; Rita Ferreira; A Sánchez Navarro; Maria Lourdes Bastos; Félix Carvalho
Sodium salicylate prevents paraquat-induced apoptosis in the rat lung.
Free radical biology & medicine 2007;43(1):48-61.
2007: João Paulo Capela; C Macedo; Paula Sério Branco; Luísa Maria Ferreira; Ana Maria Lobo; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; Ulrich Dirnagl; Andreas Meisel; Félix Carvalho
Neurotoxicity mechanisms of thioether ecstasy metabolites.
Neuroscience 2007;146(4):1743-57.
2007: Ricardo J Dinis-Oliveira; Carla Sousa; Fernando Remião; José Duarte; A Sánchez Navarro; Maria Lourdes Bastos; Félix Carvalho
Full survival of paraquat-exposed rats after treatment with sodium salicylate.
Free radical biology & medicine 2007;42(7):1017-28.
2006: Ricardo J Dinis-Oliveira; Fernando Remião; Helena Carmo; José Duarte; A Sánchez Navarro; Maria Lourdes Bastos; Félix Carvalho
Paraquat exposure as an etiological factor of Parkinson's disease.
Neurotoxicology 2006;27(6):1110-22.
2006: Ricardo J Dinis-Oliveira; Fernando Remião; José Duarte; Rita Ferreira; A Sánchez Navarro; Maria Lourdes Bastos; Félix Carvalho
P-glycoprotein induction: an antidotal pathway for paraquat-induced lung toxicity.
Free radical biology & medicine 2006;41(8):1213-24.
2006: Ricardo J Dinis-Oliveira; José Duarte; Fernando Remião; A Sánchez Navarro; Maria Lourdes Bastos; Félix Carvalho
Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats.
Toxicology 2006;227(1-2):73-85.
2006: Ricardo J Dinis-Oliveira; M J De Jesús Valle; Maria Lourdes Bastos; Félix Carvalho; A Sánchez Navarro
Kinetics of paraquat in the isolated rat lung: Influence of sodium depletion.
Xenobiotica; the fate of foreign compounds in biological systems 2006;36(8):724-37.
2006: Ricardo J Dinis-Oliveira; António Sarmento; Paulo Reis; Augusta Amaro; Fernando Remião; Maria Lourdes Bastos; Félix Carvalho
Acute paraquat poisoning: report of a survival case following intake of a potential lethal dose.
Pediatric emergency care 2006;22(7):537-40.
2006: Maria Elisa Soares; José Pereira; Maria Lourdes Bastos
Validation of a method to quantify copper and other metals in olive fruit by ETAAS. Application to the residual metal control after olive tree treatments with different copper formulations.
Journal of agricultural and food chemistry 2006;54(11):3923-8.
2006: João Paulo Capela; Karsten Ruscher; Marion Lautenschlager; Dorette Freyer; Ulrich Dirnagl; A R Gaio; Maria Lourdes Bastos; Andreas Meisel; Félix Carvalho
Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia.
Neuroscience 2006;139(3):1069-81.
2006: João Paulo Capela; Andreas Meisel; Artur Abreu; Paula Sério Branco; Luísa Maria Ferreira; Ana Maria Lobo; Fernando Remião; Maria Lourdes Bastos; Félix Carvalho
Neurotoxicity of Ecstasy metabolites in rat cortical neurons, and influence of hyperthermia.
The Journal of pharmacology and experimental therapeutics 2006;316(1):53-61.
2005: José Duarte; Anabela Leão; José Magalhães; António Ascensão; Maria Lourdes Bastos; Francisco L Amado; Laura Vilarinho; Dulce Quelhas; Hans J Appell; Félix Carvalho
Strenuous exercise aggravates MDMA-induced skeletal muscle damage in mice.
Toxicology 2005;206(3):349-58.
2004: Fernando Remião; Daniel Rettori; Derick Han; Félix Carvalho; Maria Lourdes Bastos; Enrique Cadenas
Leucoisoprenochrome-o-semiquinone formation in freshly isolated adult rat cardiomyocytes.
Chemical research in toxicology 2004;17(12):1584-90.
2004: Patrícia Valentão; Márcia Carvalho; Félix Carvalho; Eduarda Fernandes; Ricardo Neves; M Lourdes Pereira; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Hypericum androsaemum infusion increases tert-butyl hydroperoxide-induced mice hepatotoxicity in vivo.
Journal of ethnopharmacology 2004;94(2-3):345-51.
2004: Márcia Carvalho; Fernando Remião; Nuno Milhazes; Fernanda Borges; Eduarda Fernandes; Félix Carvalho; Maria Lourdes Bastos
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Toxicology 2004;200(2-3):193-203.
2004: José Duarte; Félix Carvalho; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos; José Magalhães; Hans J Appell
D-amphetamine-induced hydrogen peroxide production in skeletal muscle is modulated by monoamine oxidase inhibition.
International journal of sports medicine 2004;25(6):446-9.
2004: Cristovao F Lima; Félix Carvalho; Eduarda Fernandes; Maria Lourdes Bastos; Paula C Santos-Gomes; Manuel Fernandes-Ferreira; Cristina Pereira-Wilson
Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2004;18(4):457-65.
2004: Márcia Carvalho; Fernando Remião; Nuno Milhazes; Fernanda Borges; Eduarda Fernandes; Maria do Céu Monteiro; Maria José Gonçalves; VITOR SEABRA; Francisco M L Amado; Félix Carvalho; Maria Lourdes Bastos
Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro.
Chemical research in toxicology 2004;17(5):623-32.
2004: Maria Elisa Soares; Márcia Carvalho; Helena Carmo; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos
Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis.
Biomedical chromatography : BMC 2004;18(2):125-31.
2004: Márcia Carvalho; Nuno Milhazes; Fernando Remião; Fernanda Borges; Eduarda Fernandes; Francisco M L Amado; Terrence J Monks; Félix Carvalho; Maria Lourdes Bastos
Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates.
Archives of toxicology 2004;78(1):16-24.
2003: Patrícia Valentão; Alberto Dias; Manuel Ferreira; Branca M Silva; Paula B Andrade; Maria Lourdes Bastos; Rosa M Seabra
Variability in phenolic composition of Hypericum androsaemum.
Natural product research 2003;17(2):135-40.
2003: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Hydroxyl radical and hypochlorous acid scavenging activity of small centaury (Centaurium erythraea) infusion. A comparative study with green tea (Camellia sinensis).
Phytomedicine : international journal of phytotherapy and phytopharmacology 2003;10(6-7):517-22.
2003: Fernando Remião; Nuno Milhazes; Fernanda Borges; Félix Carvalho; Maria Lourdes Bastos; Francisco Lemos-Amado; Pedro Domingues; António J Ferrer-Correia
Synthesis and analysis of aminochromes by HPLC-photodiode array. Adrenochrome evaluation in rat blood.
Biomedical chromatography : BMC 2003;17(1):6-13.
2002: Márcia Carvalho; Gabrielle Hawksworth; Nuno Milhazes; Fernanda Borges; Terrence J Monks; Eduarda Fernandes; Félix Carvalho; Maria Lourdes Bastos
Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells.
Archives of toxicology 2002;76(10):581-8.
2002: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid.
Journal of agricultural and food chemistry 2002;50(17):4989-93.
2002: Fernando Remião; Márcia Carvalho; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
Cu2+-induced isoproterenol oxidation into isoprenochrome in adult rat calcium-tolerant cardiomyocytes.
Chemical research in toxicology 2002;15(6):861-9.
2002: Patrícia Valentão; Paula B Andrade; Eurico Silva; Ana Vicente; Henrique Santos; Maria Lourdes Bastos; Rosa M Seabra
Methoxylated xanthones in the quality control of small centaury (Centaurium erythraea) flowering tops.
Journal of agricultural and food chemistry 2002;50(3):460-3.
2001: Maria Elisa Soares; Félix Carvalho; Maria Lourdes Bastos
Determination of amphetamine and its metabolite p-hydroxyamphetamine in rat urine by reversed-phase high-performance liquid chromatography after dabsyl derivatization.
Biomedical chromatography : BMC 2001;15(7):452-6.
2001: Félix Carvalho; José Duarte; Maria J Neuparth; Helena Carmo; Eduarda Fernandes; Fernando Remião; Maria Lourdes Bastos
Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition.
Archives of toxicology 2001;75(8):465-9.
2001: Fernando Remião; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
The study of oxidative stress in freshly isolated Ca(2+)-tolerant cardiomyocytes from the adult rat.
Toxicology in vitro : an international journal published in association with BIBRA 2001;15(4-5):283-7.
2001: Patrícia Valentão; Eduarda Fernandes; Félix Carvalho; Paula B Andrade; Rosa M Seabra; Maria Lourdes Bastos
Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity.
Journal of agricultural and food chemistry 2001;49(7):3476-9.
2001: Márcia Carvalho; Félix Carvalho; Maria Lourdes Bastos
Is hyperthermia the triggering factor for hepatotoxicity induced by 3,4-methylenedioxymethamphetamine (ecstasy)? An in vitro study using freshly isolated mouse hepatocytes.
Archives of toxicology 2001;74(12):789-93.
2001: Fernando Remião; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
Copper enhances isoproterenol toxicity in isolated rat cardiomyocytes: effects on oxidative stress.
Cardiovascular toxicology 2001;1(3):195-204.
2001: Francisco Lemos-Amado; Pedro Domingues; António J Ferrer-Correia; Fernando Remião; Nuno Milhazes; Fernanda Borges; Félix Carvalho; Maria Lourdes Bastos
Electrospray tandem mass spectrometry of aminochromes.
Rapid communications in mass spectrometry : RCM 2001;15(24):2466-71.
2001: Fernando Remião; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
Cardiotoxicity studies using freshly isolated calcium-tolerant cardiomyocytes from adult rat.
In vitro cellular & developmental biology. Animal 2001;37(1):1-4.
2000: Fernando Remião; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
Simultaneous determination of reduced and oxidized glutathione in freshly isolated rat hepatocytes and cardiomyocytes by HPLC with electrochemical detection.
Biomedical chromatography : BMC 2000;14(7):468-73.
2000: Fernando Remião; Helena Carmo; Félix Carvalho; Maria Lourdes Bastos
Inhibition of glutathione reductase by isoproterenol oxidation products.
Journal of enzyme inhibition 2000;15(1):47-61.
2000: Maria Elisa Soares; Maria Lourdes Bastos; M Ferreira
Selective determination of chromium (VI) in powdered milk infant formulas by electrothermal atomization atomic absorption spectrometry after ion exchange.
Journal of AOAC International 2000;83(1):220-3.
1998: J Lameiras; Maria Elisa Soares; Maria Lourdes Bastos; M Ferreira
Quantification of total chromium and hexavalent chromium in UHT milk by ETAAS.
The Analyst 1998;123(10):2091-5.
1997: Maria Lourdes Bastos; Félix Carvalho; Fernando Remião; M E Mendes; M A Ferreira; Maria Elisa Soares; J A Timbrell
Changes in taurine levels in response to repeated administration of the beta 2-agonist salbutamol in lambs.
Journal of veterinary pharmacology and therapeutics 1997;20(1):33-7.
1997: Félix Carvalho; Fernando Remião; Maria Elisa Soares; Rita I L Catarino; Glória Queiroz; Maria Lourdes Bastos
d-Amphetamine-induced hepatotoxicity: possible contribution of catecholamines and hyperthermia to the effect studied in isolated rat hepatocytes.
Archives of toxicology 1997;71(7):429-36.
1997: Hans J Appell; José Duarte; S Glöser; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos; José M C Soares
Administration of tourniquet. II. Prevention of postischemic oxidative stress can reduce muscle edema.
Archives of orthopaedic and trauma surgery 1997;116(1-2):101-5.
1997: José Duarte; S Glöser; Fernando Remião; Félix Carvalho; Maria Lourdes Bastos; José M C Soares; Hans J Appell
Administration of tourniquet. I. Are edema and oxidative stress related to each other and to the duration of ischemia in reperfused skeletal muscle?
Archives of orthopaedic and trauma surgery 1997;116(1-2):97-100.
1996: Félix Carvalho; Fernando Remião; F Amado; Pedro Domingues; A J Correia; Maria Lourdes Bastos
d-Amphetamine interaction with glutathione in freshly isolated rat hepatocytes.
Chemical research in toxicology 1996;9(6):1031-6.
1995: E R Fernandes; Félix Carvalho; Fernando Remião; Maria Lourdes Bastos; M M Pinto; O R Gottlieb
Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes--comparison with silybin.
Pharmaceutical research 1995;12(11):1756-60.
1995: Maria Elisa Soares; Maria Lourdes Bastos; M Ferreira
Determination of arsenic, cadmium and lead in porcine and bovine kidneys by electrothermal atomic absorption spectrometry.
The Analyst 1995;120(9):2367-70.
1994: Félix Carvalho; Fernando Remião; P Vale; John A Timbrell; Maria Lourdes Bastos; M A Ferreira
Glutathione and cysteine measurement in biological samples by HPLC with a glassy carbon working detector.
Biomedical chromatography : BMC 1994;8(3):134-6.
1994: Maria Lourdes Bastos; Félix Carvalho; Maria Elisa Soares; J Fernandes; M Ferreira
Bioavailability of residues of diazepam and its metabolites.
Bollettino chimico farmaceutico 1994;133(1):27-31.
1994: José Duarte; Félix Carvalho; Maria Lourdes Bastos; José M C Soares; Hans J Appell
Do invading leucocytes contribute to the decrease in glutathione concentrations indicating oxidative stress in exercised muscle, or are they important for its recovery?
European journal of applied physiology and occupational physiology 1994;68(1):48-53.
1993: José Duarte; Hans J Appell; Félix Carvalho; Maria Lourdes Bastos; José M C Soares
Endothelium-derived oxidative stress may contribute to exercise-induced muscle damage.
International journal of sports medicine 1993;14(8):440-3.