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Ker Marshall

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TOP 3
Ashley J Warman; Martin J Warren; Andrew W Munro; Stephen E J Rigby; Jacob W Robinson; Myles R Cheesman; Andrew D Lawrence; Dominika Luciakova; Ker R Marshall; Kirsty J McLean
Characterization of Cupriavidus metallidurans CYP116B1--a thiocarbamate herbicide oxygenating P450-phthalate dioxygenase reductase fusion protein.
Rachel V Dunn; Ker R Marshall; Andrew W Munro; Nigel S Scrutton
The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex.
Min Gong; sam hay; Ker R Marshall; Andrew W Munro; Nigel S Scrutton
DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis.

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All Publications

2012: Ashley J Warman; Martin J Warren; Andrew W Munro; Stephen E J Rigby; Jacob W Robinson; Myles R Cheesman; Andrew D Lawrence; Dominika Luciakova; Ker R Marshall; Kirsty J McLean
Characterization of Cupriavidus metallidurans CYP116B1--a thiocarbamate herbicide oxygenating P450-phthalate dioxygenase reductase fusion protein.
The FEBS journal 2012;279(9):1675-93.
2008: Rachel V Dunn; Ker R Marshall; Andrew W Munro; Nigel S Scrutton
The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex.
The FEBS journal 2008;275(15):3850-8.
2007: Min Gong; sam hay; Ker R Marshall; Andrew W Munro; Nigel S Scrutton
DNA binding suppresses human AIF-M2 activity and provides a connection between redox chemistry, reactive oxygen species, and apoptosis.
The Journal of biological chemistry 2007;282(41):30331-40.
2007: Kirsten R Wolthers; Helen S Toogood; Thomas A Jowitt; Ker R Marshall; David Leys; Nigel S Scrutton
Crystal structure and solution characterization of the activation domain of human methionine synthase.
The FEBS journal 2007;274(3):738-50.
2006: Kirsty J McLean; Adrian J Dunford; Muna Sabri; Rajasekhar Neeli; Hazel M Girvan; Philip R Balding; David Leys; Harriet E Seward; Ker R Marshall; Andrew W Munro
CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen.
Biochemical Society transactions 2006;34(Pt 6):1178-82.
2006: Kirsty J McLean; Ashley J Warman; Harriet E Seward; Ker R Marshall; Hazel M Girvan; Myles R Cheesman; Michael R Waterman; Andrew W Munro
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.
Biochemistry 2006;45(27):8427-43.
2005: Ker R Marshall; Min Gong; Leigh Wodke; John H Lamb; Donald J L Jones; Peter B Farmer; Nigel S Scrutton; Andrew W Munro
The human apoptosis-inducing protein AMID is an oxidoreductase with a modified flavin cofactor and DNA binding activity.
The Journal of biological chemistry 2005;280(35):30735-40.
2005: Kirsty J McLean; Muna Sabri; Ker R Marshall; Rachel J Lawson; D G Lewis; D Clift; Philip R Balding; Adrian J Dunford; Ashley J Warman; J P McVey; A-M Quinn; Michael J Sutcliffe; Nigel S Scrutton; Andrew W Munro
Biodiversity of cytochrome P450 redox systems.
Biochemical Society transactions 2005;33(Pt 4):796-801.
2004: Adrian J Dunford; Ker R Marshall; Andrew W Munro; Nigel S Scrutton
Thermodynamic and kinetic analysis of the isolated FAD domain of rat neuronal nitric oxide synthase altered in the region of the FAD shielding residue Phe1395.
European journal of biochemistry / FEBS 2004;271(12):2548-60.
2004: Hazel M Girvan; Ker R Marshall; Rachel J Lawson; David Leys; M Gordon Joyce; John Clarkson; W Ewen Smith; Myles R Cheesman; Andrew W Munro
Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.
The Journal of biological chemistry 2004;279(22):23274-86.
2004: Mattias Gustafsson; Olivier Roitel; Ker R Marshall; Michael A Noble; Stephen K Chapman; Antonio Pessegueiro; Armand J Fulco; Myles R Cheesman; Claes von Wachenfeldt; Andrew W Munro
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Biochemistry 2004;43(18):5474-87.
2003: Andrew W Munro; Kirsty J McLean; Ker R Marshall; Ashley J Warman; G Lewis; Olivier Roitel; Michael J Sutcliffe; Carol A Kemp; S Modi; Nigel S Scrutton; David Leys
Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis.
Biochemical Society transactions 2003;31(Pt 3):625-30.
2002: Kirsty J McLean; Ker R Marshall; Alison Richmond; Iain S Hunter; Kay Fowler; Tobias Kieser; Sudagar S Gurcha; Gurdyal S Besra; Andrew W Munro
Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes.
Microbiology (Reading, England) 2002;148(Pt 10):2937-49.
2002: Ker R Marshall; Kate V Rowley; Angela Rinaldi; Iain P Nicholson; Alexander M Ishov; Gerd G Maul; Chris M Preston
Activity and intracellular localization of the human cytomegalovirus protein pp71.
The Journal of general virology 2002;83(Pt 7):1601-12.
2002: Andrew W Munro; David G Leys; Kirsty J McLean; Ker R Marshall; Tobias W B Ost; Simon Daff; Caroline S Miles; Stephen K Chapman; Dominikus Lysek; Christopher C Moser; Christopher C Page; P Leslie Dutton
P450 BM3: the very model of a modern flavocytochrome.
Trends in biochemical sciences 2002;27(5):250-7.
2000: Ker R Marshall; Robin H Lachmann; Stacey Efstathiou; Angela Rinaldi; Chris M Preston
Long-term transgene expression in mice infected with a herpes simplex virus type 1 mutant severely impaired for immediate-early gene expression.
Journal of virology 2000;74(2):956-64.
1999: Angela Rinaldi; Ker R Marshall; Chris M Preston
A non-cytotoxic herpes simplex virus vector which expresses Cre recombinase directs efficient site specific recombination.
Virus research 1999;65(1):11-20.