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Alberto Martelli

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William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Richard A Franklin; Michelle M LaHair; Alberto M Martelli; Kristin M Stadelman; Linda S Steelman; Steven L Abrams; James A McCubrey
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment.
Matilde Y Follo; Pietro Gobbi; Francesco A Manzoli; Sandra Marmiroli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Carlo Finelli; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C β1 signaling, epigenetics and treatments in MDS.
William H Chappell; Richard A Franklin; Michelle M LaHair; Massimo Libra; Alberto M Martelli; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Jerry Polesel; Linda Steelman; Agostino Tafuri; Renato Talamini; Steven L Abrams; Saverio Candido; Melchiorre Cervello; James A McCubrey
Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.

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2013: William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Richard A Franklin; Michelle M LaHair; Alberto M Martelli; Kristin M Stadelman; Linda S Steelman; Steven L Abrams; James A McCubrey
Increased NGAL (Lnc2) expression after chemotherapeutic drug treatment.
Advances in biological regulation 2013;53(1):146-55.
2013: Matilde Y Follo; Pietro Gobbi; Francesco A Manzoli; Sandra Marmiroli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Carlo Finelli; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C β1 signaling, epigenetics and treatments in MDS.
Advances in biological regulation 2013;53(1):2-7.
2012: William H Chappell; Richard A Franklin; Michelle M LaHair; Massimo Libra; Alberto M Martelli; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Jerry Polesel; Linda Steelman; Agostino Tafuri; Renato Talamini; Steven L Abrams; Saverio Candido; Melchiorre Cervello; James A McCubrey
Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.
Cell cycle (Georgetown, Tex.) 2012;11(23):4447-61.
2012: Matilde Y Follo; Lucia Manzoli; Alberto M Martelli; giovanni martinelli; S Mongiorgi; S Paolini; C Clissa; Carlo Finelli; G Fioravanti; Lucio Cocco
Activation of nuclear inositide signalling pathways during erythropoietin therapy in low-risk MDS patients.
Leukemia 2012;26(12):2474-82.
2012: C Simioni; Giovanna Tabellini; Pier Luigi Tazzari; D Bressanin; A Cani; S Capitani; Francesca Chiarini; Camilla Evangelisti; James A McCubrey; Fraia Melchionda; Luca M Neri; P Pagliaro; A Pession; Francesca Ricci; Alberto M Martelli
Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia.
Leukemia 2012;26(11):2336-42.
2012: William H Chappell; Massimo Libra; Alberto M Martelli; Steven L Abrams; Ralph Arlinghaus; Saverio Candido; Melchiorre Cervello; Giuseppe Montalto; Jerry Polesel; Linda Steelman; Renato Talamini; James A McCubrey
Effects of ectopic expression of NGAL on doxorubicin sensitivity.
Oncotarget 2012;3(10):1236-45.
2012: James A McCubrey; Sanja Mijatovic; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Linda Steelman; Agostino Tafuri; Maria Clorinda Mazzarino; Steven L Abrams; Jörg Bäsecke; Saverio Candido; Melchiorre Cervello; William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Paolo Fagone; Richard A Franklin; Massimo Libra; Danijela Maksimovic-Ivanic; Grazia Malaponte; Alberto M Martelli
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.
Oncotarget 2012;3(10):1068-111.
2012: James A McCubrey; Sanja Mijatovic; Michele Milella; Giuseppe Montalto; Ferdinando Nicoletti; Linda Steelman; Agostino Tafuri; Maria Clorinda Mazzarino; Steven L Abrams; Jörg Bäsecke; Saverio Candido; Melchiorre Cervello; William H Chappell; Francesca Chiarini; Lucio Cocco; Camilla Evangelisti; Paolo Fagone; Massimo Libra; Danijela Maksimovic-Ivanic; Grazia Malaponte; Alberto M Martelli
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.
Oncotarget 2012;3(9):954-87.
2012: Daniela Bressanin; Francesca Buontempo; Francesca Chiarini; Camilla Evangelisti; James A McCubrey; Fraia Melchionda; Pasqualepaolo Pagliaro; Andrea Pession; Francesca Ricci; Giovanna Tabellini; Pier Luigi Tazzari; Alberto M Martelli
Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: eliminating activity by targeting at different levels.
Oncotarget 2012;3(8):811-23.
2012: Francesca Buontempo; Francesca Chiarini; Milena Fini; James A McCubrey; Fraia Melchionda; Luca M Neri; Andrea Pession; Giovanna Tabellini; Daniela Bressanin; Alberto M Martelli
Activity of the selective IκB kinase inhibitor BMS-345541 against T-cell acute lymphoblastic leukemia: involvement of FOXO3a.
Cell cycle (Georgetown, Tex.) 2012;11(13):2467-75.
2012: Alberto M Martelli; Andrea Ognibene; Anna Maria Billi; Daniela Bressanin; Alessandra Cappellini; Francesca Chiarini; Camilla Evangelisti; Lucia Manzoli; James A McCubrey
Targeting the liver kinase B1/AMP-activated protein kinase pathway as a therapeutic strategy for hematological malignancies.
Expert opinion on therapeutic targets 2012;16(7):729-42.
2012: Matilde Y Follo; marco gobbi; Lucia Manzoli; Alberto M Martelli; S Mongiorgi; M Piazzi; D Russo; C Clissa; C Colombi; C Filì; Carlo Finelli; Lucio Cocco
Epigenetic regulation of nuclear PI-PLCbeta1 signaling pathway in low-risk MDS patients during azacitidine treatment.
Leukemia 2012;26(5):943-50.
2012: Alberto M Martelli; Daniela Bressanin; Francesca Buontempo; Alessandra Cappellini; Francesca Chiarini; Camilla Evangelisti; Milena Fini; James A McCubrey
Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment.
Oncotarget 2012;3(4):371-94.
2012: James A McCubrey; Sanja Mijatovic; Negin Misaghian; Giuseppeo Montalto; Ferdinando Nicoletti; Linda Steelman; Francac Stivala; Steven L Abrams; Jorg Basecke; Antonio Bonati; Melchiorre Cervello; William H Chappell; Lucio Cocco; Camilla Evangelisti; Piotr Laidler; Massimo Libra; Giovanni Ligresti; Danijela Maksimovic-Ivanic; Alberto M Martelli
Targeting the cancer initiating cell: the ultimate target for cancer therapy.
Current pharmaceutical design 2012;18(13):1784-95.
2012: Roberta Fiume; Matilde Y Follo; David R Jones; Willem Jan Keune; Alberto M Martelli; Giulia Ramazzotti; Lilly Somner; Yvette Bultsma; Nullin Divecha; Irene Faenza; Lucio Cocco
Nuclear phosphoinositides: location, regulation and function.
Sub-cellular biochemistry 2012;59():335-61.
2012: Matilde Y Follo; Alberto M Martelli; James A McCubrey; Sara Mongiorgi; Manuela Piazzi; Giulia Ramazzotti; Patrizia Santi; Irene Faenza; Carlo Finelli; Lucio Cocco
Nuclear PI-PLCβ1 and myelodysplastic syndromes: genetics and epigenetics.
Current pharmaceutical design 2012;18(13):1751-4.
2012: Alberto M Martelli; James A McCubrey; Francesca Ricci; Giovanna Tabellini; Roberta Bortul; Francesca Chiarini; Camilla Evangelisti; Francesco Antonio Manzoli
PI3K/AKT/mTORC1 and MEK/ERK signaling in T-cell acute lymphoblastic leukemia: new options for targeted therapy.
Advances in biological regulation 2012;52(1):214-27.
2012: Matilde Y Follo; Francesco Antonio Manzoli; Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Irene Faenza; Roberta Fiume; Lucio Cocco
Revisiting nuclear phospholipase C signalling in MDS.
Advances in biological regulation 2012;52(1):2-6.
2012: James A McCubrey; Kazuo Umezawa; Steven L Abrams; William H Chappell; Lucio Cocco; Richard A Franklin; Alberto M Martelli; Linda S Steelman
Novel approaches to target cancer initiating cells-eliminating the root of the cancer.
Advances in biological regulation 2012;52(1):249-64.
2011: James A McCubrey; Sanja Mijatovic; Giuseppe Montalto; Ferdinando Nicoletti; Linda Steelman; Franca Stivala; Steven L Abrams; Jörg Bäsecke; Melchiorre Cervello; William H Chappell; Lucio Cocco; C Ruth Kempf; Massimo Libra; Danijela Maksimovic-Ivanic; Graziella Malaponte; Alberto M Martelli
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways.
Journal of cellular physiology 2011;226(11):2762-81.
2011: Alberto M Martelli; James A McCubrey; Andrea Ognibene; Milena Fini; Kaoru Goto; Daniela Bressanin; Francesca Buontempo; Lucio Cocco; Camilla Evangelisti
Nuclear phosphoinositides and their roles in cell biology and disease.
Critical reviews in biochemistry and molecular biology 2011;46(5):436-57.
2011: Linda Steelman; Franca Stivala; Ellis W T Wong; Patrick Navolanic; Ferdinando Nicoletti; Steven L Abrams; William H Chappell; Lucio Cocco; Lyudmyla B Drobot; Richard A Franklin; Massimo Libra; Alberto M Martelli; James A McCubrey
Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells.
Cell cycle (Georgetown, Tex.) 2011;10(17):3003-15.
2011: Melissa L Sokolosky; Kristin M Stadelman; Linda Steelman; Franca Stivala; Steven L Abrams; William H Chappell; Lyudmyla B Drobot; Richard A Franklin; Massimo Libra; Alberto M Martelli; Ferdinando Nicoletti; James A McCubrey
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy.
Oncotarget 2011;2(7):538-50.
2011: Linda Steelman; Franca Stivala; F Nicoletti; P Ruvolo; V Ruvolo; Steven L Abrams; Jörg Bäsecke; W Chappell; Marco Donia; Camilla Evangelisti; P Fagone; Richard A Franklin; C R Kempf; Massimo Libra; Alberto M Martelli; James A McCubrey
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Leukemia 2011;25(7):1080-94.
2011: Alberto M Martelli; F Nicoletti; P Ruvolo; V Ruvolo; Linda Steelman; Franca Stivala; Steven L Abrams; Jörg Bäsecke; W Chappell; Marco Donia; Camilla Evangelisti; P Fagone; C R Kempf; Massimo Libra; James A McCubrey
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Leukemia 2011;25(7):1064-79.
2011: Camilla Evangelisti; Francesca Ricci; Pier Luigi Tazzari; Giovanna Tabellini; Michela Battistelli; Elisabetta Falcieri; Francesca Chiarini; Roberta Bortul; Fraia Melchionda; P Pagliaro; Andrea Pession; James A McCubrey; Alberto M Martelli
Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Leukemia 2011;25(5):781-91.
2011: Camilla Evangelisti; Francesca Ricci; Pier Luigi Tazzari; Francesca Chiarini; Michela Battistelli; Elisabetta Falcieri; Andrea Ognibene; Pasqualepaolo Pagliaro; Lucio Cocco; James A McCubrey; Alberto M Martelli
Preclinical testing of the Akt inhibitor triciribine in T-cell acute lymphoblastic leukemia.
Journal of cellular physiology 2011;226(3):822-31.
2011: Matilde Y Follo; Carlo Finelli; S Mongiorgi; C Clissa; Francesca Chiarini; Giulia Ramazzotti; S Paolini; giovanni martinelli; Alberto M Martelli; Lucio Cocco
Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes.
Leukemia 2011;25(2):271-80.
2011: W L Blalock; Alberto Bavelloni; M Piazzi; F Tagliavini; Irene Faenza; Alberto M Martelli; Matilde Y Follo; Lucio Cocco
Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.
Leukemia 2011;25(2):236-45.
2011: Alberto M Martelli; James A McCubrey; Giulia Ramazzotti; Camilla Evangelisti; Milena Fini; M Y Follo; Roberto Giardino; Lamberto Manzoli; Lucio Cocco
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells.
Current medicinal chemistry 2011;18(18):2715-26.
2011: Lucio Cocco; Matilde Y Follo; Irene Faenza; Roberta Fiume; Giulia Ramazzotti; George Weber; Alberto M Martelli; Francesco Antonio Manzoli
Physiology and pathology of nuclear phospholipase C β1.
Advances in enzyme regulation 2011;51(1):2-12.
2010: Francesca Chiarini; Cecilia Grimaldi; Francesca Ricci; Pier Luigi Tazzari; Camilla Evangelisti; Andrea Ognibene; Michela Battistelli; Elisabetta Falcieri; Fraia Melchionda; Andrea Pession; Pasqualepaolo Pagliaro; James A McCubrey; Alberto M Martelli
Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against T-cell acute lymphoblastic leukemia.
Cancer research 2010;70(20):8097-107.
2010: Alberto M Martelli; Camilla Evangelisti; Francesca Chiarini; Cecilia Grimaldi; Alessandra Cappellini; Andrea Ognibene; James A McCubrey
The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis.
Biochimica et biophysica acta 2010;1803(9):991-1002.
2010: Alberto M Martelli; Camilla Evangelisti; Francesca Chiarini; James A McCubrey
The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.
Oncotarget 2010;1(2):89-103.
2010: Alberto M Martelli; Francesca Chiarini; Camilla Evangelisti; Cecilia Grimaldi; Andrea Ognibene; Lucia Manzoli; Anna Maria Billi; James A McCubrey
The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin signaling network and the control of normal myelopoiesis.
Histology and histopathology 2010;25(5):669-80.
2010: Matilde Y Follo; Sara Mongiorgi; Carlo Finelli; Cristina Clissa; Giulia Ramazzotti; Roberta Fiume; Irene Faenza; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Nuclear inositide signaling in myelodysplastic syndromes.
Journal of cellular biochemistry 2010;109(6):1065-71.
2010: Alberto M Martelli; Veronica Papa; Pier Luigi Tazzari; Francesca Ricci; Camilla Evangelisti; Francesca Chiarini; C Grimaldi; Alessandra Cappellini; giovanni martinelli; Emanuela Ottaviani; P Pagliaro; S Horn; J Bäsecke; L H Lindner; H Eibl; James A McCubrey
Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms.
Leukemia 2010;24(4):687-98.
2010: Camilla Evangelisti; Gian Carlo Gaboardi; Anna Maria Billi; Andrea Ognibene; Kaoru Goto; Pier Luigi Tazzari; James A McCubrey; Alberto M Martelli
Identification of a functional nuclear export sequence in diacylglycerol kinase-zeta.
Cell cycle (Georgetown, Tex.) 2010;9(2):384-8.
2010: A D'Emilio; L Biagiotti; Sabrina Burattini; Michela Battistelli; Barbara Canonico; C Evangelisti; Paola Ferri; Stefano Papa; Alberto M Martelli; Elisabetta Falcieri
Morphological and biochemical patterns in skeletal muscle apoptosis.
Histology and histopathology 2010;25(1):21-32.
2010: Lucio Cocco; Matilde Y Follo; Irene Faenza; Anna Maria Billi; Giulia Ramazzotti; Alberto M Martelli; Lucia Manzoli; George Weber
Inositide signaling in the nucleus: from physiology to pathology.
Advances in enzyme regulation 2010;50(1):2-11.
2009: William L Blalock; Cecilia Grimaldi; Federica Fala; Matilde Follo; Stefan Horn; Jorg Basecke; Giovanni Martinelli; Lucio Cocco; Alberto M Martelli
PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation.
Journal of cellular physiology 2009;221(1):232-41.
2009: Matilde Y Follo; Carlo Finelli; Sara Mongiorgi; Cristina Clissa; Costanza Bosi; Nicoletta Testoni; Francesca Chiarini; Giulia Ramazzotti; Michele Baccarani; Alberto M Martelli; Lucia Manzoli; Giovanni Martinelli; Lucio Cocco
Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16811-6.
2009: Alberto M Martelli; Camilla Evangelisti; Francesca Chiarini; Cecilia Grimaldi; Lucia Manzoli; James A McCubrey
Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia.
Expert opinion on investigational drugs 2009;18(9):1333-49.
2009: Lisa Bregoli; Francesca Chiarini; Andrea Gambarelli; Gianluca Sighinolfi; Antonietta M Gatti; Patrizia Santi; Alberto M Martelli; Lucio Cocco
Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines.
Toxicology 2009;262(2):121-9.
2009: Alessandra Cappellini; Francesca Chiarini; Andrea Ognibene; James A McCubrey; Alberto M Martelli
The cyclin-dependent kinase inhibitor roscovitine and the nucleoside analog sangivamycin induce apoptosis in caspase-3 deficient breast cancer cells independent of caspase mediated P-glycoprotein cleavage: implications for therapy of drug resistant breast cancers.
Cell cycle (Georgetown, Tex.) 2009;8(9):1421-5.
2009: Camilla Evangelisti; Annalisa Astolfi; Gian Carlo Gaboardi; Pier Luigi Tazzari; Andrea Pession; Kaoru Goto; Alberto M Martelli
TIS21/BTG2/PC3 and cyclin D1 are key determinants of nuclear diacylglycerol kinase-zeta-dependent cell cycle arrest.
Cellular signalling 2009;21(5):801-9.
2009: Francesca Chiarini; Federica Falà; Pier Luigi Tazzari; Francesca Ricci; Annalisa Astolfi; Andrea Pession; Pasqualepaolo Pagliaro; James A McCubrey; Alberto M Martelli
Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia.
Cancer research 2009;69(8):3520-8.
2009: Matilde Y Follo; Carlo Finelli; Cristina Clissa; Sara Mongiorgi; Costanza Bosi; giovanni martinelli; Michele Baccarani; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Phosphoinositide-phospholipase C beta1 mono-allelic deletion is associated with myelodysplastic syndromes evolution into acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(5):782-90.
2009: Lucio Cocco; Irene Faenza; Matilde Y Follo; Anna Maria Billi; Giulia Ramazzotti; Veronica Papa; Alberto M Martelli; Lucia Manzoli
Nuclear inositides: PI-PLC signaling in cell growth, differentiation and pathology.
Advances in enzyme regulation 2009;49(1):2-10.
2008: Pier Luigi Tazzari; Giovanna Tabellini; Francesca Ricci; Veronica Papa; Roberta Bortul; Francesca Chiarini; Camilla Evangelisti; giovanni martinelli; Andrea Bontadini; Lucio Cocco; James A McCubrey; Alberto M Martelli
Synergistic proapoptotic activity of recombinant TRAIL plus the Akt inhibitor Perifosine in acute myelogenous leukemia cells.
Cancer research 2008;68(22):9394-403.
2008: Giulia Ramazzotti; Irene Faenza; Gian Carlo Gaboardi; Manuela Piazzi; Alberto Bavelloni; Roberta Fiume; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Catalytic activity of nuclear PLC-beta(1) is required for its signalling function during C2C12 differentiation.
Cellular signalling 2008;20(11):2013-21.
2008: Federica Falà; William L Blalock; Pier Luigi Tazzari; Alessandra Cappellini; Francesca Chiarini; giovanni martinelli; Agostino Tafuri; James A McCubrey; Lucio Cocco; Alberto M Martelli
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.
Molecular pharmacology 2008;74(3):884-95.
2008: Giovanna Baldini; Cristina Ponti; Roberta Bortul; Paola Narducci; Vittorio Grill; Alberto M Martelli
Sparc localizes to the blebs of hobit cells and human primary osteoblasts.
Journal of cellular biochemistry 2008;104(6):2310-23.
2008: Francesca Chiarini; M Del Sole; S Mongiorgi; Gian Carlo Gaboardi; Alessandra Cappellini; Irina Mantovani; Matilde Y Follo; JA McCubrey; Alberto M Martelli
The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism.
Leukemia 2008;22(6):1106-16.
2008: Nicoletta Zini; Alberto Bavelloni; Gina Lisignoli; Sonia Ghisu; Aurelio Valmori; Alberto M Martelli; Andrea Facchini; Nadir M Maraldi
PKC-zeta expression is lower in osteoblasts from arthritic patients: IL1-beta and TNF-alpha induce a similar decrease in non-arthritic human osteoblasts.
Journal of cellular biochemistry 2008;103(2):547-55.
2008: Lucio Cocco; Irene Faenza; Matilde Y Follo; Giulia Ramazzotti; Gian Carlo Gaboardi; Anna Maria Billi; Alberto M Martelli; Lucia Manzoli
Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes.
Advances in enzyme regulation 2008;48():2-9.
2008: Irene Faenza; Lisa Bregoli; Giulia Ramazzotti; Gian Carlo Gaboardi; Matilde Y Follo; Sara Mongiorgi; Anna Maria Billi; Lucia Manzoli; Alberto M Martelli; Lucio Cocco
Nuclear phospholipase C beta1 and cellular differentiation.
Frontiers in bioscience : a journal and virtual library 2008;13():2452-63.
2008: Veronica Papa; Pier Luigi Tazzari; Francesca Chiarini; Alessandra Cappellini; Francesca Ricci; Anna Maria Billi; Camilla Evangelisti; Emanuela Ottaviani; giovanni martinelli; Nicoletta Testoni; JA McCubrey; Alberto M Martelli
Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
Leukemia 2008;22(1):147-60.
2008: Matilde Y Follo; Carlo Finelli; Costanza Bosi; giovanni martinelli; S Mongiorgi; Michele Baccarani; Lucia Manzoli; W L Blalock; Alberto M Martelli; Lucio Cocco
PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes.
Leukemia 2008;22(1):198-200.
2007: Camilla Evangelisti; Pier Luigi Tazzari; Massimo Riccio; Roberta Fiume; Yasukazu Hozumi; Federica Falà; Kaoru Goto; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Nuclear diacylglycerol kinase-zeta is a negative regulator of cell cycle progression in C2C12 mouse myoblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(12):3297-307.
2007: Matilde Y Follo; Sara Mongiorgi; Costanza Bosi; Alessandra Cappellini; Carlo Finelli; Francesca Chiarini; Veronica Papa; Massimo Libra; giovanni martinelli; Lucio Cocco; Alberto M Martelli
The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
Cancer research 2007;67(9):4287-94.
2007: Pier Luigi Tazzari; Giovanna Tabellini; Roberta Bortul; Veronica Papa; Camilla Evangelisti; Tiziana Grafone; giovanni martinelli; JA McCubrey; Alberto M Martelli
The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.
Leukemia 2007;21(5):886-96.
2007: Camilla Evangelisti; Roberta Bortul; Federica Falà; Giovanna Tabellini; Kaoru Goto; Alberto M Martelli
Nuclear diacylglycerol kinases: emerging downstream regulators in cell signaling networks.
Histology and histopathology 2007;22(5):573-9.
2007: Pier Luigi Tazzari; Alessandra Cappellini; Francesca Ricci; Camilla Evangelisti; Veronica Papa; Tiziana Grafone; giovanni martinelli; Roberto Conte; Lucio Cocco; JA McCubrey; Alberto M Martelli
Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts.
Leukemia 2007;21(3):427-38.
2007: Irene Faenza; Giulia Ramazzotti; Alberto Bavelloni; Roberta Fiume; Gian Carlo Gaboardi; Matilde Y Follo; R Stewart Gilmour; Alberto M Martelli; Katya Ravid; Lucio Cocco
Inositide-dependent phospholipase C signaling mimics insulin in skeletal muscle differentiation by affecting specific regions of the cyclin D3 promoter.
Endocrinology 2007;148(3):1108-17.
2007: Stefania Laurent; Giulio L Palmisano; Alberto M Martelli; Tomohiro Kato; Pier Luigi Tazzari; Ivana Pierri; Marino Clavio; Beatrice Dozin; Giuseppe Balbi; Mauro Megna; Anna Morabito; Teresa Lamparelli; Andrea Bacigalupo; marco gobbi; Maria Pia Pistillo
CTLA-4 expressed by chemoresistant, as well as untreated, myeloid leukaemia cells can be targeted with ligands to induce apoptosis.
British journal of haematology 2007;136(4):597-608.
2007: Alberto M Martelli; Lucio Cocco; Silvano Capitani; Sebastiano Miscia; Stefano Papa; Francesco Antonio Manzoli
Nuclear phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3-kinase, Akt, and PTen: emerging key regulators of anti-apoptotic signaling and carcinogenesis.
European journal of histochemistry : EJH 2007;51 Suppl 1():125-31.
2007: Alberto M Martelli; Pier Luigi Tazzari; Camilla Evangelisti; Francesca Chiarini; W L Blalock; Anna Maria Billi; Lucia Manzoli; JA McCubrey; Lucio Cocco
Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
Current medicinal chemistry 2007;14(19):2009-23.
2007: Alberto M Martelli; Camilla Evangelist; Anna Maria Billi; Lucia Manzoli; Veronica Papa; Lucio Cocco
Intranuclear 3'-phosphoinositide metabolism and apoptosis protection in PC12 cells.
Acta bio-medica : Atenei Parmensis 2007;78 Suppl 1():113-9.
2007: Lucio Cocco; Matilde Y Follo; Irene Faenza; Alberto Bavelloni; Anna Maria Billi; Alberto M Martelli; Lucia Manzoli
Nuclear inositide signaling: an appraisal of phospholipase C beta 1 behavior in myelodysplastic and leukemia cells.
Advances in enzyme regulation 2007;47():2-9.
2006: Camilla Evangelisti; Massimo Riccio; Irene Faenza; Nicoletta Zini; Yasukazu Hozumi; Kaoru Goto; Lucio Cocco; Alberto M Martelli
Subnuclear localization and differentiation-dependent increased expression of DGK-zeta in C2C12 mouse myoblasts.
Journal of cellular physiology 2006;209(2):370-8.
2006: Alberto M Martelli; Irene Faenza; Anna Maria Billi; Lucia Manzoli; Camilla Evangelisti; Federica Falà; Lucio Cocco
Intranuclear 3'-phosphoinositide metabolism and Akt signaling: new mechanisms for tumorigenesis and protection against apoptosis?
Cellular signalling 2006;18(8):1101-7.
2006: Maria Nyåkern; Alessandra Cappellini; Irina Mantovani; Alberto M Martelli
Synergistic induction of apoptosis in human leukemia T cells by the Akt inhibitor perifosine and etoposide through activation of intrinsic and Fas-mediated extrinsic cell death pathways.
Molecular cancer therapeutics 2006;5(6):1559-70.
2006: Alberto M Martelli; Maria Nyåkern; Giovanna Tabellini; Roberta Bortul; Pier Luigi Tazzari; Camilla Evangelisti; Lucio Cocco
Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.
Leukemia 2006;20(6):911-28.
2006: Irina Mantovani; Alessandra Cappellini; Pier Luigi Tazzari; Veronica Papa; Lucio Cocco; Alberto M Martelli
Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells.
Journal of cellular physiology 2006;207(3):836-44.
2006: Alberto M Martelli; Camilla Evangelisti; Maria Nyakern; Francesco Antonio Manzoli
Nuclear protein kinase C.
Biochimica et biophysica acta 2006;1761(5-6):542-51.
2006: Maria Nyåkern; Pier Luigi Tazzari; Carlo Finelli; Costanza Bosi; Matilde Y Follo; Tiziana Grafone; Pier Paolo Piccaluga; giovanni martinelli; Lucio Cocco; Alberto M Martelli
Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients.
Leukemia 2006;20(2):230-8.
2006: Lucio Cocco; Alberto M Martelli; Roberta Fiume; Irene Faenza; Anna Maria Billi; Francesco Antonio Manzoli
Signal transduction within the nucleus: revisiting phosphoinositide inositide-specific phospholipase Cbeta1.
Advances in enzyme regulation 2006;46():2-11.
2006: Camilla Evangelisti; Roberta Bortul; Giovanna Tabellini; Veronica Papa; Lucio Cocco; Alberto M Martelli
Nuclear expression of diacylglycerol kinases: possible involvement in DNA replication.
European journal of histochemistry : EJH 2006;50(1):9-13.
2005: Alessandra Cappellini; Irina Mantovani; Pier Luigi Tazzari; Tiziana Grafone; giovanni martinelli; Lucio Cocco; Alberto M Martelli
Application of flow cytometry to molecular medicine: detection of tumor necrosis factor-related apoptosis-inducing ligand receptors in acute myeloid leukaemia blasts.
International journal of molecular medicine 2005;16(6):1041-8.
2005: Elisabetta Contardi; Giulio L Palmisano; Pier Luigi Tazzari; Alberto M Martelli; Federica Falà; Marina Fabbi; Tomohiro Kato; Enrico Lucarelli; Davide Donati; Letizia Polito; Andrea Bolognesi; Francesca Ricci; Sandra Salvi; Vittoria Gargaglione; Stefano Mantero; Marco Alberghini; Giovanni Battista Ferrara; Maria Pia Pistillo
CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction.
International journal of cancer. Journal international du cancer 2005;117(4):538-50.
2005: Alberto M Martelli; Roberta Fiume; Irene Faenza; Giovanna Tabellini; C Evangelista; Roberta Bortul; Matilde Y Follo; Federica Falà; Lucio Cocco
Nuclear phosphoinositide specific phospholipase C (PI-PLC)-beta 1: a central intermediary in nuclear lipid-dependent signal transduction.
Histology and histopathology 2005;20(4):1251-60.
2005: Alberto M Martelli; Matilde Y Follo; Camilla Evangelisti; Federica Falà; Roberta Fiume; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid metabolism: more than just second messenger generation?
Journal of cellular biochemistry 2005;96(2):285-92.
2005: Giovanna Tabellini; Pier Luigi Tazzari; Roberta Bortul; Camilla Evangelisti; Anna Maria Billi; Tiziana Grafone; giovanni martinelli; Michele Baccarani; Alberto M Martelli
Phosphoinositide 3-kinase/Akt inhibition increases arsenic trioxide-induced apoptosis of acute promyelocytic and T-cell leukaemias.
British journal of haematology 2005;130(5):716-25.
2005: Nicoletta Zini; Gina Lisignoli; Liliana Solimando; Alberto Bavelloni; Aurelio Valmori; Sandra Cristino; Alberto M Martelli; Andrea Facchini; Nadir M Maraldi
Quantitative immunodetection of key elements of polyphosphoinositide signal transduction in osteoblasts from arthritic patients shows a direct correlation with cell proliferation.
Histochemistry and cell biology 2005;124(2):131-7.
2005: Lucia Manzoli; Alberto M Martelli; Anna Maria Billi; Irene Faenza; Roberta Fiume; Lucio Cocco
Nuclear phospholipase C: involvement in signal transduction.
Progress in lipid research 2005;44(4):185-206.
2005: Roberta Fiume; Irene Faenza; Alessandro Matteucci; Annalisa Astolfi; Marco Vitale; Alberto M Martelli; Lucio Cocco
Nuclear phospholipase C beta1 (PLCbeta1) affects CD24 expression in murine erythroleukemia cells.
The Journal of biological chemistry 2005;280(25):24221-6.
2005: Roberta Bortul; Pier Luigi Tazzari; Anna Maria Billi; Giovanna Tabellini; Irina Mantovani; Alessandra Cappellini; Tiziana Grafone; giovanni martinelli; Roberto Conte; Alberto M Martelli
Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway.
British journal of haematology 2005;129(5):677-86.
2005: Irene Faenza; Anna Maria Billi; Matilde Y Follo; Roberta Fiume; Alberto M Martelli; Lucio Cocco; Lucia Manzoli
Nuclear phospholipase C signaling through type 1 IGF receptor and its involvement in cell growth and differentiation.
Anticancer research 2005;25(3B):2039-41.
2005: Giovanna Tabellini; Alessandra Cappellini; Pier Luigi Tazzari; Federica Falà; Anna Maria Billi; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
Journal of cellular physiology 2005;202(2):623-34.
2005: Lucio Cocco; Lucia Manzoli; Giandomenico Palka; Alberto M Martelli
Nuclear phospholipase C beta1, regulation of the cell cycle and progression of acute myeloid leukemia.
Advances in enzyme regulation 2005;45():126-35.
2005: Alessandra Cappellini; Pier Luigi Tazzari; Irina Mantovani; Anna Maria Billi; Cristina Tassi; Francesca Ricci; Roberto Conte; Alberto M Martelli
Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation.
Apoptosis : an international journal on programmed cell death 2005;10(1):141-52.
2005: Alberto M Martelli; Giovanna Tabellini; Roberta Bortul; Pier Luigi Tazzari; Alessandra Cappellini; Anna Maria Billi; Lucio Cocco
Involvement of the phosphoinositide 3-kinase/Akt signaling pathway in the resistance to therapeutic treatments of human leukemias.
Histology and histopathology 2005;20(1):239-52.
2004: Giovanna Tabellini; Anna Maria Billi; Federica Falà; Alessandra Cappellini; Camilla Evagelisti; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Nuclear diacylglycerol kinase-theta is activated in response to nerve growth factor stimulation of PC12 cells.
Cellular signalling 2004;16(11):1263-71.
2004: Pier Luigi Tazzari; Alessandra Cappellini; Tiziana Grafone; Irina Mantovani; Francesca Ricci; Anna Maria Billi; Emanuela Ottaviani; Roberto Conte; giovanni martinelli; Alberto M Martelli
Detection of serine 473 phosphorylated Akt in acute myeloid leukaemia blasts by flow cytometry.
British journal of haematology 2004;126(5):675-81.
2004: Giovanna Tabellini; Pier Luigi Tazzari; Roberta Bortul; Anna Maria Billi; Roberto Conte; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
British journal of haematology 2004;126(4):574-82.
2004: Irene Faenza; Alberto Bavelloni; Roberta Fiume; Patrizia Santi; Alberto M Martelli; Anna Maria Billi; Vincenza Rita Lo Vasco; Lucia Manzoli; Lucio Cocco
Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation.
Journal of cellular physiology 2004;200(2):291-6.
2004: Alberto M Martelli; Federica Falà; Irene Faenza; Anna Maria Billi; Alessandra Cappellini; Lucia Manzoli; Lucio Cocco
Metabolism and signaling activities of nuclear lipids.
Cellular and molecular life sciences : CMLS 2004;61(10):1143-56.
2004: Alberto M Martelli; Alessandra Cappellini; Pier Luigi Tazzari; Anna Maria Billi; Cristina Tassi; Francesca Ricci; Federica Falà; Roberto Conte
Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes.
Haematologica 2004;89(4):471-9.
2004: Lucio Cocco; Lucia Manzoli; Ottavio Barnabei; Alberto M Martelli
Significance of subnuclear localization of key players of inositol lipid cycle.
Advances in enzyme regulation 2004;44():51-60.
2004: Lucio Cocco; S Capitani; N M Maraldi; Alberto M Martelli; Giovanni Mazzotti; Francesco Antonio Manzoli
Significance of nuclear phospholipase C signaling through type 1 IGF receptor.
Journal of endocrinological investigation 2004;27(6 Suppl):143-5.
2004: Lucia Manzoli; Anna Maria Billi; Alberto M Martelli; Lucio Cocco
Regulation of nuclear phospholipase C activity.
Acta biochimica Polonica 2004;51(2):391-5.
2004: Alberto M Martelli; Giovanni Mazzotti; Silvano Capitani
Nuclear protein kinase C isoforms and apoptosis.
European journal of histochemistry : EJH 2004;48(1):89-94.
2004: Vanessa Nicolin; Maria A Sandrucci; Marisa Basa; Renato Bareggi; Alberto M Martelli; Paola Narducci; Vittorio Grill
Expression of protein kinase C (PKC) alpha, delta, epsilon, zeta in primary chick chondrocyte cultures: immunocytochemical study.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2004;109(1):55-65.
2004: Alberto M Martelli; Lucia Manzoli; Lucio Cocco
Nuclear inositides: facts and perspectives.
Pharmacology & therapeutics 2004;101(1):47-64.
2003: Alessandra Cappellini; Giovanna Tabellini; Margit Zweyer; Roberta Bortul; Pier Luigi Tazzari; Anna Maria Billi; Federica Falà; Lucio Cocco; Alberto M Martelli
The phosphoinositide 3-kinase/Akt pathway regulates cell cycle progression of HL60 human leukemia cells through cytoplasmic relocalization of the cyclin-dependent kinase inhibitor p27(Kip1) and control of cyclin D1 expression.
Leukemia 2003;17(11):2157-67.
2003: Elisabetta Falcieri; Sabrina Burattini; Roberta Bortul; Francesca Luchetti; Giovanna Tabellini; Pier Luigi Tazzari; Alessandra Cappellini; Lucio Cocco; Alberto M Martelli
Intranucleolar localization of DNA topoisomerase IIalpha is a distinctive feature of necrotic, but not of apoptotic, Jurkat T-cells.
Microscopy research and technique 2003;62(3):192-200.
2003: Alberto M Martelli; Irene Faenza; Anna Maria Billi; Federica Falà; Lucio Cocco; Lucia Manzoli
Nuclear protein kinase C isoforms: key players in multiple cell functions?
Histology and histopathology 2003;18(4):1301-12.
2003: Alberto M Martelli; Pier Luigi Tazzari; Giovanna Tabellini; Roberta Bortul; Anna Maria Billi; Lucia Manzoli; A Ruggeri; Roberto Conte; Lucio Cocco
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
Leukemia 2003;17(9):1794-805.
2003: Giovanna Tabellini; Roberta Bortul; Spartaco Santi; Massimo Riccio; Giovanna Baldini; Alessandra Cappellini; Anna Maria Billi; Ronald Berezney; Alessandra Ruggeri; Lucio Cocco; Alberto M Martelli
Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.
Experimental cell research 2003;287(1):143-54.
2003: Paola Borgatti; Alberto M Martelli; Giovanna Tabellini; Alfonso Bellacosa; Silvano Capitani; Luca M Neri
Threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin.
Journal of cellular physiology 2003;196(1):79-88.
2003: Irene Faenza; Alberto Bavelloni; Roberta Fiume; Giovanna Lattanzi; Nadir M Maraldi; R Stewart Gilmour; Alberto M Martelli; Pann-Ghill Suh; Anna Maria Billi; Lucio Cocco
Up-regulation of nuclear PLCbeta1 in myogenic differentiation.
Journal of cellular physiology 2003;195(3):446-52.
2003: Alberto M Martelli; Giovanna Tabellini; Paola Borgatti; Roberta Bortul; Silvano Capitani; Luca M Neri
Nuclear lipids: new functions for old molecules?
Journal of cellular biochemistry 2003;88(3):455-61.
2003: Roberta Bortul; Pier Luigi Tazzari; Alessandra Cappellini; Giovanna Tabellini; Anna Maria Billi; Renato Bareggi; Lucia Manzoli; Lucio Cocco; Alberto M Martelli
Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.
Leukemia 2003;17(2):379-89.
2003: Lucio Cocco; Lucia Manzoli; Ottavio Barnabei; R Stewart Gilmour; Alberto M Martelli
Re-examination of the significance of nuclear localization of PLCbeta1 in the likelihood of its involvement in neoplastic cell growth.
Advances in enzyme regulation 2003;43():1-13.
2003: Luca M Neri; Paola Borgatti; Pier Luigi Tazzari; Roberta Bortul; Alessandra Cappellini; Giovanna Tabellini; Alfonso Bellacosa; Silvano Capitani; Alberto M Martelli
The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells.
Molecular cancer research : MCR 2003;1(3):234-46.
2002: Luca M Neri; Paola Borgatti; Silvano Capitani; Alberto M Martelli
The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system.
Biochimica et biophysica acta 2002;1584(2-3):73-80.
2002: Alberto M Martelli; Lucia Manzoli; Irene Faenza; Roberta Bortul; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid signaling and its potential involvement in malignant transformation.
Biochimica et biophysica acta 2002;1603(1):11-7.
2002: Luca M Neri; Paola Borgatti; Silvano Capitani; Alberto M Martelli
Protein kinase C isoforms and lipid second messengers: a critical nuclear partnership?
Histology and histopathology 2002;17(4):1311-6.
2002: Alberto M Martelli; Elisabetta Falcieri; Margit Zweyer; Roberta Bortul; Giovanna Tabellini; Alessandra Cappellini; Lucio Cocco; Lucia Manzoli
The controversial nuclear matrix: a balanced point of view.
Histology and histopathology 2002;17(4):1193-205.
2002: Giovanna Tabellini; Roberta Bortul; Michela Aluigi; Anna Maria Billi; Renato Bareggi; Vittorio Grill; Paola Narducci; Alberto M Martelli
Binding of elements of protein kinase C-alpha regulatory domain to lamin B1.
Cellular signalling 2002;14(10):819-27.
2002: Daniela Peruzzi; Michela Aluigi; Lucia Manzoli; Anna Maria Billi; Francesco Paolo Di Giorgio; Manuela Morleo; Alberto M Martelli; Lucio Cocco
Molecular characterization of the human PLC beta1 gene.
Biochimica et biophysica acta 2002;1584(1):46-54.
2002: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Renato Bareggi; Lucia Manzoli; Paola Narducci; Lucio Cocco
Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways.
Cellular and molecular life sciences : CMLS 2002;59(7):1129-37.
2002: Irene Faenza; Alessandro Matteucci; Alberto Bavelloni; Sandra Marmiroli; Alberto M Martelli; R Stewart Gilmour; Pann-Ghill Suh; Lucia Manzoli; Lucio Cocco
Nuclear PLCbeta(1) acts as a negative regulator of p45/NF-E2 expression levels in Friend erythroleukemia cells.
Biochimica et biophysica acta 2002;1589(3):305-10.
2002: Vittorio Grill; Maria A Sandrucci; Marisa Basa; Vanessa Nicolin; Paola Narducci; Renato Bareggi; Alberto M Martelli
Immunochemical and immunocytochemical expression of protein kinase c isoenzymes alpha, delta, epsilon and zeta in primary adherent cultures of chick chondrocytes.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2002;107(2):73-84.
2002: Luca M Neri; Roberta Bortul; Paola Borgatti; Giovanna Tabellini; Giovanna Baldini; Silvano Capitani; Alberto M Martelli
Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells.
Molecular biology of the cell 2002;13(3):947-64.
2002: Pier Luigi Tazzari; Alessandra Cappellini; Roberta Bortul; Francesca Ricci; Anna Maria Billi; Giovanna Tabellini; Roberto Conte; Alberto M Martelli
Flow cytometric detection of total and serine 473 phosphorylated Akt.
Journal of cellular biochemistry 2002;86(4):704-15.
2002: Lucio Cocco; Alberto M Martelli; Marco Vitale; Mirella Falconi; Ottavio Barnabei; R Stewart Gilmour; Francesco Antonio Manzoli
Inositides in the nucleus: regulation of nuclear PI-PLCbeta1.
Advances in enzyme regulation 2002;42():181-93.
2002: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Irene Faenza; Alessandra Cappellini; Renato Bareggi; Lucia Manzoli; Lucio Cocco
Molecular characterization of protein kinase C-alpha binding to lamin A.
Journal of cellular biochemistry 2002;86(2):320-30.
2002: Luca M Neri; Roberta Bortul; Giovanna Tabellini; Paola Borgatti; Giovanna Baldini; Claudio Celeghini; Silvano Capitani; Alberto M Martelli
Erythropoietin-induced erythroid differentiation of K562 cells is accompanied by the nuclear translocation of phosphatidylinositol 3-kinase and intranuclear generation of phosphatidylinositol (3,4,5) trisphosphate.
Cellular signalling 2002;14(1):21-9.
2001: Alberto M Martelli; Roberta Bortul; Giovanna Tabellini; Michela Aluigi; Daniela Peruzzi; Renato Bareggi; Paola Narducci; Lucio Cocco
Re-examination of the mechanisms regulating nuclear inositol lipid metabolism.
FEBS letters 2001;505(1):1-6.
2001: Marco Vitale; Alessandro Matteucci; Lucia Manzoli; Luigi Fabrizio Rodella; A R Mariani; giorgio zauli; Mirella Falconi; Anna Maria Billi; Alberto M Martelli; R Stewart Gilmour; Lucio Cocco
Interleukin 2 activates nuclear phospholipase Cbeta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(10):1789-91.
2001: Renato Bareggi; Maria A Sandrucci; Alberto M Martelli; A Forabosco; Paola Narducci; Vittorio Grill
Morphological features and measurements in a human fetus with karyotype 69, XXX: comparison with fetuses of the same CRL, without chromosomal anomalies.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(3):261-72.
2001: Giovanna Tabellini; Massimo Riccio; Giovanna Baldini; Renato Bareggi; Anna Maria Billi; Vittorio Grill; Paola Narducci; Alberto M Martelli
Further considerations on the intranuclear distribution of HMGI/Y proteins.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(3):251-60.
2001: Lucio Cocco; Alberto M Martelli; R Stewart Gilmour; SG Rhee; Francesco Antonio Manzoli
Nuclear phospholipase C and signaling.
Biochimica et biophysica acta 2001;1530(1):1-14.
2001: Giovanna Tabellini; Giovanna Baldini; G Baldini; Roberta Bortul; Renato Bareggi; Paola Narducci; Alberto M Martelli
Localization of the small monomeric GTPases Rab3D and Rab3A in the AtT-20 rat pituitary cell line.
European journal of histochemistry : EJH 2001;45(4):347-56.
2001: Roberta Bortul; Michela Aluigi; Pier Luigi Tazzari; Giovanna Tabellini; Giovanna Baldini; Renato Bareggi; Paola Narducci; Alberto M Martelli
Phosphoinositide-specific phospholipase Cbeta1 expression is not linked to nerve growth factor-induced differentiation, cell survival or cell cycle control in PC12 rat pheocromocytoma cells.
Journal of cellular biochemistry 2001;84(1):56-67.
2001: Lucio Cocco; Nadir M Maraldi; Silvano Capitani; Alberto M Martelli; Francesco Antonio Manzoli
Nuclear localization and signalling activity of inositol lipids.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2001;106(2 Suppl 1):31-43.
2001: Alberto M Martelli; Margit Zweyer; RL Ochs; Pier Luigi Tazzari; Giovanna Tabellini; Paola Narducci; Roberta Bortul
Nuclear apoptotic changes: an overview.
Journal of cellular biochemistry 2001;82(4):634-46.
2001: Roberta Bortul; Margit Zweyer; Anna Maria Billi; Giovanna Tabellini; RL Ochs; Renato Bareggi; Lucio Cocco; Alberto M Martelli
Nuclear changes in necrotic HL-60 cells.
Journal of cellular biochemistry. Supplement 2001;Suppl 36():19-31.
2001: Lucio Cocco; Alberto M Martelli; Ottavio Barnabei; Francesco Antonio Manzoli
Nuclear inositol lipid signaling.
Advances in enzyme regulation 2001;41():361-84.
2000: Alberto M Martelli; Anna Maria Billi; Lucia Manzoli; Irene Faenza; Michela Aluigi; Mirella Falconi; Anto De Pol; R Stewart Gilmour; Lucio Cocco
Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation.
FEBS letters 2000;486(3):230-6.
2000: Vittorio Grill; Maria A Sandrucci; Roberto Di Lenarda; Milena Cadenaro; Paola Narducci; Renato Bareggi; Alberto M Martelli
Biocompatibility evaluation of dental metal alloys in vitro: expression of extracellular matrix molecules and its relationship to cell proliferation rates.
Journal of biomedical materials research 2000;52(3):479-87.
2000: Alberto M Martelli; Giovanna Baldini; Giovanna Tabellini; Darshan K Koticha; Renato Bareggi; G Baldini
Rab3A and Rab3D control the total granule number and the fraction of granules docked at the plasma membrane in PC12 cells.
Traffic (Copenhagen, Denmark) 2000;1(12):976-86.
2000: Vittorio Grill; Maria A Sandrucci; Roberto Di Lenarda; Marisa Basa; Paola Narducci; Alberto M Martelli; Renato Bareggi
In vitro evaluation of the biocompatibility of dental alloys: fibronectin expression patterns and relationships to cellular proliferation rates.
Quintessence international (Berlin, Germany : 1985) 2000;31(10):741-7.
2000: Alberto M Martelli; Paola Borgatti; Roberta Bortul; Massimiliano Manfredini; Leo Massari; Silvano Capitani; Luca M Neri
Phosphatidylinositol 3-kinase translocates to the nucleus of osteoblast-like MC3T3-E1 cells in response to insulin-like growth factor I and platelet-derived growth factor but not to the proapoptotic cytokine tumor necrosis factor alpha.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(9):1716-30.
2000: Paola Borgatti; Alberto M Martelli; Alfonso Bellacosa; R Casto; Leo Massari; Silvano Capitani; Luca M Neri
Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors.
FEBS letters 2000;477(1-2):27-32.
2000: Alberto M Martelli; I Robuffo; Roberta Bortul; RL Ochs; Francesca Luchetti; Lucio Cocco; Margit Zweyer; Renato Bareggi; E Falcieri
Behavior of nucleolar proteins during the course of apoptosis in camptothecin-treated HL60 cells.
Journal of cellular biochemistry 2000;78(2):264-77.
2000: Vittorio Grill; Marisa Basa; Maria A Sandrucci; Paola Narducci; Renato Bareggi; Alberto M Martelli
Immunocytochemical expression of protein kinase C isoenzymes alpha, delta, epsilon and zeta in differentiating chick chondrocytes in vitro.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 2000;105(2):97-108.
2000: Vittorio Grill; Maria A Sandrucci; Roberto Di Lenarda; E Dorigo; Paola Narducci; Alberto M Martelli; Renato Bareggi
Cell proliferation rates and fibronectin arrangement as parameters for biocompatibility evaluation of dental metal alloys in vitro.
Journal of oral science 2000;42(1):1-7.
2000: Alberto M Martelli; Giovanna Tabellini; Roberta Bortul; Lucia Manzoli; Renato Bareggi; Giovanna Baldini; V Grill; Margit Zweyer; Paola Narducci; Lucio Cocco
Enhanced nuclear diacylglycerol kinase activity in response to a mitogenic stimulation of quiescent Swiss 3T3 cells with insulin-like growth factor I.
Cancer research 2000;60(4):815-21.
2000: Alberto M Martelli; Pier Luigi Tazzari; Roberta Bortul; M Riccio; Giovanna Tabellini; S Santi; Flavia Frabetti; D Musiani; Renato Bareggi; Roberto Conte
Nuclear matrix protein is released from apoptotic white cells during cold (1-6 degrees C) storage of concentrated red cell units and might induce antibody response in multiply transfused patients.
Transfusion 2000;40(2):169-77.
2000: Lucio Cocco; Alberto M Martelli; Giovanni Mazzotti; Ottavio Barnabei; Francesco Antonio Manzoli
Inositides and the nucleus: phospholipase Cbeta family localization and signaling activity.
Advances in enzyme regulation 2000;40():83-95.
1999: Luca M Neri; Alberto M Martelli; Paola Borgatti; Maria Luisa Colamussi; Marco Marchisio; Silvano Capitani
Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(15):2299-310.
1999: Luca M Neri; Y Raymond; Antonio Giordano; Paola Borgatti; Marco Marchisio; Silvano Capitani; Alberto M Martelli
Spatial distribution of lamin A and B1 in the K562 cell nuclear matrix stabilized with metal ions.
Journal of cellular biochemistry 1999;75(1):36-45.
1999: Alberto M Martelli; N Sang; Paola Borgatti; Silvano Capitani; Luca M Neri
Multiple biological responses activated by nuclear protein kinase C.
Journal of cellular biochemistry 1999;74(4):499-521.
1999: Lucia Manzoli; Anna Maria Billi; Irene Faenza; Alessandro Matteucci; Alberto M Martelli; Daniela Peruzzi; Mirella Falconi; SG Rhee; R Stewart Gilmour; Lucio Cocco
Nuclear phospholipase C: a novel aspect of phosphoinositide signalling.
Anticancer research 1999;19(5A):3753-6.
1999: Alberto M Martelli; Roberta Bortul; Renato Bareggi; Giovanna Tabellini; V Grill; Giovanna Baldini; Paola Narducci
The pro-apoptotic drug camptothecin stimulates phospholipase D activity and diacylglycerol production in the nucleus of HL-60 human promyelocytic leukemia cells.
Cancer research 1999;59(16):3961-7.
1999: Alberto M Martelli; Silvano Capitani; Luca M Neri
The generation of lipid signaling molecules in the nucleus.
Progress in lipid research 1999;38(4):273-308.
1999: Alberto M Martelli; Roberta Bortul; Renato Bareggi; V Grill; Paola Narducci; Margit Zweyer
Biochemical and morphological changes in the nuclear matrix prepared from apoptotic HL-60 cells: effect of different stabilizing procedures.
Journal of cellular biochemistry 1999;74(1):99-110.
1999: Luca M Neri; Roberta Bortul; Margit Zweyer; Giovanna Tabellini; Paola Borgatti; Marco Marchisio; Renato Bareggi; Silvano Capitani; Alberto M Martelli
Influence of different metal ions on the ultrastructure, biochemical properties, and protein localization of the K562 cell nuclear matrix.
Journal of cellular biochemistry 1999;73(3):342-54.
1999: Alberto M Martelli; Lucio Cocco; Renato Bareggi; Giovanna Tabellini; R Rizzoli; M D Ghibellini; Paola Narducci
Insulin-like growth factor-I-dependent stimulation of nuclear phospholipase C-beta1 activity in Swiss 3T3 cells requires an intact cytoskeleton and is paralleled by increased phosphorylation of the phospholipase.
Journal of cellular biochemistry 1999;72(3):339-48.
1999: Luca M Neri; Y Raymond; Antonio Giordano; Silvano Capitani; Alberto M Martelli
Lamin A is part of the internal nucleoskeleton of human erythroleukemia cells.
Journal of cellular physiology 1999;178(3):284-95.
1999: Alberto M Martelli; Roberta Bortul; Frank Fackelmayer; Pier Luigi Tazzari; Renato Bareggi; Paola Narducci; Margit Zweyer
Biochemical and morphological characterization of the nuclear matrix from apoptotic HL-60 cells.
Journal of cellular biochemistry 1999;72(1):35-46.
1999: Luca M Neri; Silvano Capitani; Paola Borgatti; Alberto M Martelli
Lipid signaling and cell responses at the nuclear level.
Histology and histopathology 1999;14(1):321-35.
1998: Luca M Neri; Paola Borgatti; Silvano Capitani; Alberto M Martelli
Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.
The Journal of biological chemistry 1998;273(45):29738-44.
1998: Renato Bareggi; F Bratina; Vittorio Grill; Paola Narducci; Alberto M Martelli
Atypical isoenzymes of PKC-iota, -lambda, -mu: relative distribution in mouse foetal and neonatal organs.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia 1998;103(4):127-43.
1998: Alberto M Martelli; Silvano Capitani; Luca M Neri
Prereplicative increase of nuclear matrix-bound DNA polymerase-alpha and primase activities in HeLa S3 cells following dilution of long-term cultures.
Journal of cellular biochemistry 1998;71(1):11-20.
1997: Luca M Neri; Margit Zweyer; Elisabetta Falcieri; Roberta Bortul; Alberto M Martelli
Changes in the subnuclear distribution of two RNA metabolism-related proteins can be detected in nuclear scaffold or matrix prepared by different techniques.
Histochemistry and cell biology 1997;108(6):525-36.
1997: Luca M Neri; B M Riederer; A Valmori; S Capitani; Alberto M Martelli
Different concentrations of Mg++ ions affect nuclear matrix protein distribution during thermal stabilization of isolated nuclei.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(10):1317-28.
1997: Vittorio Grill; Maria A Sandrucci; Marisa Basa; Roberto Di Lenarda; E Dorigo; Paola Narducci; Alberto M Martelli; Giorgio Delbello; Renato Bareggi
The influence of dental metal alloys on cell proliferation and fibronectin arrangement in human fibroblast cultures.
Archives of oral biology 1997;42(9):641-7.
1997: Alberto M Martelli; Renato Bareggi; Roberta Bortul; V Grill; Paola Narducci; Margit Zweyer
The nuclear matrix and apoptosis.
Histochemistry and cell biology 1997;108(1):1-10.
1997: Luca M Neri; Frank Fackelmayer; Margit Zweyer; T Kohwi-Shigematsu; Alberto M Martelli
Subnuclear localization of S/MAR-binding proteins is differently affected by in vitro stabilization with heat or Cu2+.
Chromosoma 1997;106(2):81-93.
1997: Luca M Neri; Alberto M Martelli; N M Maraldi
Redistribution of DNA topoisomerase II beta after in vitro stabilization of human erythroleukemic nuclei by heat or Cu++ revealed by confocal microscopy.
Microscopy research and technique 1997;36(3):179-87.
1997: Margit Zweyer; B M Riederer; RL Ochs; Frank Fackelmayer; T Kohwi-Shigematsu; Renato Bareggi; Paola Narducci; Alberto M Martelli
Association of nuclear matrix proteins with granular and threaded nuclear bodies in cell lines undergoing apoptosis.
Experimental cell research 1997;230(2):325-36.
1997: Luca M Neri; B M Riederer; R A Marugg; S Capitani; Alberto M Martelli
Nuclear scaffold proteins are differently sensitive to stabilizing treatment by heat or Cu++.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(2):295-305.
1996: Lucia Manzoli; R S Gilmour; Alberto M Martelli; Anna Maria Billi; Lucio Cocco
Nuclear inositol lipid cycle: a new central intermediary in signal transduction.
Anticancer research 1996;16(6A):3283-6.
1996: Renato Bareggi; V Grill; Margit Zweyer; M A Sandrucci; Alberto M Martelli; Paola Narducci; A Forabosco
On the assessment of the growth patterns in human fetal limbs: longitudinal measurements and allometric analysis.
Early human development 1996;45(1-2):11-25.
1996: Alberto M Martelli; S Lach; V Grill; R S Gilmour; L Cocco; Paola Narducci; Renato Bareggi
Expression and immunohistochemical localization of eight phospholipase C isoforms in adult male mouse cerebellar cortex.
Acta histochemica 1996;98(2):131-41.
1996: V Grill; M A Sandrucci; M Basa; R Di Lenarda; E Dorigo; Alberto M Martelli; Renato Bareggi; Paola Narducci
The presence of implant materials influences fibronectin arrangement and cell growth in fibroblast cultures.
Bollettino della Società italiana di biologia sperimentale 1996;72(3-4):87-94.
1996: Alberto M Martelli; Renato Bareggi; L Cocco; Francesco Antonio Manzoli
Stimulation of nuclear polyphosphoinositide synthesis by GTP-gamma-S: a potential regulatory role for nuclear GTP-binding proteins.
Biochemical and biophysical research communications 1996;218(1):182-6.
1996: Renato Bareggi; Paola Narducci; V Grill; S Lach; Alberto M Martelli
Selective distribution of multiple protein kinase C isoforms in mouse cerebellar cortex.
Biology of the cell / under the auspices of the European Cell Biology Organization 1996;87(1-2):55-63.
1995: Luca M Neri; Beat M Riederer; R A Marugg; Silvano Capitani; Alberto M Martelli
Analysis by confocal microscopy of the behavior of heat shock protein 70 within the nucleus and of a nuclear matrix polypeptide during prolonged heat shock response in HeLa cells.
Experimental cell research 1995;221(2):301-10.
1995: Margit Zweyer; Renato Bareggi; V Grill; M R Soranzo; R A Marugg; Beat M Riederer; Paola Narducci; Alberto M Martelli
Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells.
Experimental cell research 1995;221(1):27-40.
1995: Lucia Manzoli; Anna Maria Billi; R S Gilmour; Alberto M Martelli; Alessandro Matteucci; S Rubbini; G Weber; Lucio Cocco
Phosphoinositide signaling in nuclei of Friend cells: tiazofurin down-regulates phospholipase C beta 1.
Cancer research 1995;55(14):2978-80.
1995: Luca M Neri; Beat M Riederer; R A Marugg; Silvano Capitani; Alberto M Martelli
The effect of sodium tetrathionate stabilization on the distribution of three nuclear matrix proteins in human K562 erythroleukemia cells.
Histochemistry and cell biology 1995;104(1):29-36.
1995: Nicoletta Zini; Alberto M Martelli; Luca M Neri; Alberto Bavelloni; Patrizia Sabatelli; Spartaco Santi; Nadir M Maraldi
Immunocytochemical evaluation of protein kinase C translocation to the inner nuclear matrix in 3T3 mouse fibroblasts after IGF-I treatment.
Histochemistry and cell biology 1995;103(6):447-57.
1995: V Grill; Alberto M Martelli; Renato Bareggi; Spartaco Santi; M Basa; Margit Zweyer; L Cocco; Paola Narducci
Protein kinase C isoenzymes in mouse harderian gland. Differential expression of the alpha- and epsilon-isoforms during pregnancy. Protein kinase C-OC.
Histochemistry and cell biology 1995;103(4):255-62.
1995: Renato Bareggi; Alberto M Martelli; V Grill; M A Sandrucci; Margit Zweyer; Paola Narducci
Protein kinase C (PKC) isoenzymes exhibit specific expression in the vertebral column of human fetuses.
Bollettino della Società italiana di biologia sperimentale 1995;71(3-4):83-90.
1995: V Grill; Margit Zweyer; Renato Bareggi; Alberto M Martelli; M Basa; Paola Narducci
A simple and rapid staining technique for plastic embedded cartilage and bone.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1995;70(2):75-80.
1995: Giovanni Mazzotti; Nicoletta Zini; E Rizzi; R Rizzoli; A Galanzi; Andrea Ognibene; Spartaco Santi; Alessandro Matteucci; Alberto M Martelli; Nadir M Maraldi
Immunocytochemical detection of phosphatidylinositol 4,5-bisphosphate localization sites within the nucleus.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995;43(2):181-91.
1995: Alberto M Martelli; A Cataldi; Lucia Manzoli; Anna Maria Billi; S Rubbini; R S Gilmour; Lucio Cocco
Inositides in nuclei of Friend cells: changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation.
Cellular signalling 1995;7(1):53-6.
1995: Alberto M Martelli; Lucia Manzoli; S Rubbini; Anna Maria Billi; Renato Bareggi; Lucio Cocco
The protein composition of Friend cell nuclear matrix stabilized by various treatments. Different recovery of nucleolar proteins B23 and C23 and nuclear lamins.
Biology of the cell / under the auspices of the European Cell Biology Organization 1995;83(1):15-22.
1995: Lucio Cocco; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; R S Gilmour; Francesco Antonio Manzoli
Nuclear inositol lipid cycle and differentiation.
Advances in enzyme regulation 1995;35():23-33.
1995: Nadir M Maraldi; Nicoletta Zini; Andrea Ognibene; Alberto M Martelli; M Barbieri; Giovanni Mazzotti; Francesco Antonio Manzoli
Immunocytochemical detection of the intranuclear variations of phosphatidylinositol 4,5-bisphosphate amount associated with changes of activity and amount of phospholipase C beta 1 in cells exposed to mitogenic or differentiating agonists.
Biology of the cell / under the auspices of the European Cell Biology Organization 1995;83(2-3):201-10.
1994: V Grill; Margit Zweyer; M Basa; Renato Bareggi; Alberto M Martelli; F Bratina; Paola Narducci
Histochemical and ultrastructural investigation on the cytotypes in the mouse Harderian gland.
Bollettino della Società italiana di biologia sperimentale 1994;70(8-9):199-206.
1994: Luca M Neri; Spartaco Santi; R A Marugg; Beat M Riederer; Silvano Capitani; Amelia Cataldi; Alberto M Martelli
In vitro heat exposure induces a redistribution of nuclear matrix proteins in human K562 erythroleukemia cells.
Experimental cell research 1994;213(1):275-85.
1994: Lucio Cocco; Alberto M Martelli; R S Gilmour
Inositol lipid cycle in the nucleus.
Cellular signalling 1994;6(5):481-5.
1994: Luca M Neri; Anna Maria Billi; Lucia Manzoli; S Rubbini; R S Gilmour; Lucio Cocco; Alberto M Martelli
Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF.
FEBS letters 1994;347(1):63-8.
1994: Alberto M Martelli; Renato Bareggi; Paola Narducci
Catalytic properties of DNA polymerase alpha activity associated with the heart-stabilized nuclear matrix prepared from HeLa S3 cells.
Cell biochemistry and function 1994;12(2):129-35.
1994: Alberto M Martelli; Anna Maria Billi; R S Gilmour; Luca M Neri; Lucia Manzoli; Andrea Ognibene; Lucio Cocco
Phosphoinositide signaling in nuclei of Friend cells: phospholipase C beta down-regulation is related to cell differentiation.
Cancer research 1994;54(10):2536-40.
1994: Alberto M Martelli; Renato Bareggi; Beat M Riederer; R A Marugg; Paola Narducci
The effect of in vitro heating on the distribution of nuclear matrix polypeptides in HeLa cells.
Cell biology international 1994;18(3):151-8.
1994: Alberto M Martelli; L M Neri; Loris Zamai; Renato Bareggi; Lucia Manzoli; L Cocco
6-Iodoacetamidofluorescein labelling to assess the state of sulphhydril groups after thermal stabilization of isolated nuclei.
The Histochemical journal 1994;26(2):179-88.
1994: Alberto M Martelli; Lucio Cocco
No discrete complexes containing DNA polymerase alpha activity can be solubilized from the heat-stabilized nuclear matrix prepared from HeLa S3 cells.
Cell biochemistry and function 1994;12(1):37-44.
1994: Margit Zweyer; M Basa; Alberto M Martelli; Renato Bareggi
Morphological and ultrastructural observations on mouse embryo chondrocytes cultured in vitro with and without ascorbic acid.
Bollettino della Società italiana di biologia sperimentale 1994;70(1-2):11-7.
1993: Alberto M Martelli
On the association of DNA primase activity with the nuclear matrix in HeLa S3 cells.
Cell biochemistry and function 1993;11(4):287-90.
1993: Nicoletta Zini; Alberto M Martelli; Lucio Cocco; Francesco Antonio Manzoli; Nadir M Maraldi
Phosphoinositidase C isoforms are specifically localized in the nuclear matrix and cytoskeleton of Swiss 3T3 cells.
Experimental cell research 1993;208(1):257-69.
1993: Anna Maria Billi; Lucio Cocco; Alberto M Martelli; R S Gilmour; G Weber
Tiazofurin-induced changes in inositol lipid cycle in nuclei of Friend erythroleukemia cells.
Biochemical and biophysical research communications 1993;195(1):8-12.
1993: Lucio Cocco; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; Giovanni Mazzotti; Ottavio Barnabei; Francesco Antonio Manzoli
Nuclear phosphoinositidase C during growth factor stimulation.
Advances in enzyme regulation 1993;33():157-69.
1992: Elisabetta Falcieri; P Gobbi; Patrizia Sabatelli; Spartaco Santi; Fulvia Farabegoli; Rosa Alba Rana; Amelia Cataldi; Nadir M Maraldi; Alberto M Martelli
A combined ultrastructural approach to the study of nuclear matrix thermal stabilization.
Histochemistry 1992;98(2):121-9.
1992: Alberto M Martelli; R S Gilmour; R Bareggi; Lucio Cocco
The effect of in vitro heat exposure on the recovery of nuclear matrix-bound DNA polymerase alpha activity during the different phases of the cell cycle in synchronized HeLa S3 cells.
Experimental cell research 1992;201(2):470-6.
1992: Luca M Neri; Alberto M Martelli; Maurizio Previati; Aurelio Valmori; Silvano Capitani
From two dimensional (2D) to three dimensional (3D) analysis by confocal microscopy.
Liver 1992;12(4 Pt 2):268-79.
1992: Luca M Neri; Giovanni Mazzotti; Silvano Capitani; Nadir M Maraldi; Caterina Cinti; N Baldini; Rosa Alba Rana; Alberto M Martelli
Nuclear matrix-bound replicational sites detected in situ by 5-bromodeoxyuridine.
Histochemistry 1992;98(1):19-32.
1992: Alberto M Martelli; R S Gilmour; Valeria Bertagnolo; Luca M Neri; Lucia Manzoli; Lucio Cocco
Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells.
Nature 1992;358(6383):242-5.
1992: P Santi; Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Rosa Alba Rana; Amelia Cataldi; G Lattanzi; Renato Bareggi; Lucio Cocco
Changes in polyphosphoinositide levels in rat liver nuclei in response to prolactin, a known hepatic mitogen.
Cellular signalling 1992;4(4):385-91.
1992: Alberto M Martelli; Anna Maria Billi; R S Gilmour; Lucia Manzoli; Di Primio Roberto; Lucio Cocco
Mouse and human hemopoietic cell lines of erythroid lineage express lamins A,B and C.
Biochemical and biophysical research communications 1992;185(1):271-6.
1992: M Mazzoni; C Carini; Alessandro Matteucci; Alberto M Martelli; Valeria Bertagnolo; Maurizio Previati; Rosa Alba Rana; Amelia Cataldi; Silvano Capitani
Increased phosphorylation of nuclear substrates for rat brain protein kinase C in regenerating rat liver nuclei.
Cellular signalling 1992;4(3):313-9.
1992: Alberto M Martelli; Elisabetta Falcieri; P Gobbi; Lucia Manzoli; Amelia Cataldi; Rosa Alba Rana; Lucio Cocco
Further considerations on the thermal stabilization of the nuclear matrix in mouse erythroleukemia cells.
Cell biology international reports 1992;16(4):307-17.
1992: Lucio Cocco; Alberto M Martelli; R S Gilmour; Rosa Alba Rana; Ottavio Barnabei; Francesco Antonio Manzoli
Changes in inositol lipid metabolism and protein kinase C translocation in nuclei of mitogen stimulated Swiss 3T3 cells.
Advances in enzyme regulation 1992;32():91-103.
1991: Alberto M Martelli; Elisabetta Falcieri; P Gobbi; Lucia Manzoli; R S Gilmour; Lucio Cocco
Heat-induced stabilization of the nuclear matrix: a morphological and biochemical analysis in murine erythroleukemia cells.
Experimental cell research 1991;196(2):216-25.
1991: Alberto M Martelli; C Carini; Sandra Marmiroli; M Mazzoni; P J Barker; R S Gilmour; Silvano Capitani
Nuclear protein kinases in rat liver: evidence for increased histone H1 phosphorylating activity during liver regeneration.
Experimental cell research 1991;195(1):255-62.
1991: Alberto M Martelli; R S Gilmour; Luca M Neri; Lucia Manzoli; A N Corps; Lucio Cocco
Mitogen-stimulated events in nuclei of Swiss 3T3 cells. Evidence for a direct link between changes of inositol lipids, protein kinase C requirement and the onset of DNA synthesis.
FEBS letters 1991;283(2):243-6.
1991: Alberto M Martelli; Luca M Neri; R S Gilmour; P J Barker; N S Huskisson; Francesco Antonio Manzoli; Lucio Cocco
Temporal changes in intracellular distribution of protein kinase C in Swiss 3T3 cells during mitogenic stimulation with insulin-like growth factor I and bombesin: translocation to the nucleus follows rapid changes in nuclear polyphosphoinositides.
Biochemical and biophysical research communications 1991;177(1):480-7.
1991: Alberto M Martelli; Lucio Cocco; Francesco Antonio Manzoli
On the association of DNA polymerase alpha activity with the nuclear matrix in HeLa cells.
Cell biology international reports 1991;15(2):131-40.
1990: Alberto M Martelli; R S Gilmour; Francesco Antonio Manzoli; Lucio Cocco
Calcium free inositol (1,4,5)-trisphosphate stimulates protein kinase C dependent protein phosphorylation in nuclei isolated from mitogen-treated Swiss 3T3 cells.
Biochemical and biophysical research communications 1990;173(1):149-55.
1990: Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Francesco Antonio Manzoli; Lucio Cocco
Temperature-dependent association of DNA polymerase alpha activity with the nuclear matrix.
Experimental cell research 1990;190(2):227-32.
1990: Alberto M Martelli; Anna Maria Billi; C De Marchis; Lucia Manzoli; Lucio Cocco
Probing the sulfhydryl groups of nuclear matrix proteins with 6-iodoacetamidofluorescein.
Cell biology international reports 1990;14(5):409-18.
1989: Alberto M Martelli; R S Gilmour; Elisabetta Falcieri; Francesco Antonio Manzoli; Lucio Cocco
Mitogen-stimulated phosphorylation of nuclear proteins in Swiss 3T3 cells: evidence for a protein kinase C requirement.
Experimental cell research 1989;185(1):191-202.
1989: Francesco Antonio Manzoli; Alberto M Martelli; Silvano Capitani; Nadir M Maraldi; R Rizzoli; Ottavio Barnabei; Lucio Cocco
Nuclear polyphosphoinositides during cell growth and differentiation.
Advances in enzyme regulation 1989;28():25-34.
1988: Lucio Cocco; S Papa; Nadir M Maraldi; P Santi; Alberto M Martelli; R Rizzoli; Francesco Antonio Manzoli
Chromatin structural transitions following histone H1 displacement by phosphatidylserine vesicles and low pH treatment. A multiparametric analysis involving flow cytometry, electron microscopy, and nuclease digestion.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1988;36(1):65-71.
1987: S Papa; Silvano Capitani; Alessandro Matteucci; M Vitale; P Santi; Alberto M Martelli; Nadir M Maraldi; Francesco Antonio Manzoli
Flow cytometric analysis of isolated rat liver nuclei during growth.
Cytometry 1987;8(6):595-601.
1987: Lucio Cocco; Alberto M Martelli; Anna Maria Billi; A Cataldi; Sebastiano Miscia; M R Mottola; Lucia Manzoli
Phospholipids as components of the nuclear matrix: their possible biological significance.
Basic and applied histochemistry 1987;31(3):413-9.