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Jamey Marth

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Chemicals & Drugs

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Glycosylation

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Publications

TOP 3
Sally L Orr; James C Paulson; Peter Sobieszczuk; Hua Tian; Xiaoqun Fang; Dzung Le; Jeffrey M Long; Bo Ma; Jamey D Marth; Nissi M Varki
A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.
Elizabeth R Sturgill; Michael Tiemeyer; KATARINA VAJN; Won Ho Yang; Kazuhiro Aoki; Daniel Colacurcio; Marija Heffer; Pablo H H Lopez; Ileana Lorenzini; Senka Majić; Jamey D Marth; Ronald Schnaar
Biosynthesis of the major brain gangliosides GD1a and GT1b.
Won Ho Yang; Prabhjit K Grewal; Jamey D Marth; Claudia Nussbaum; Markus Sperandio
Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands.

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2013: Sally L Orr; James C Paulson; Peter Sobieszczuk; Hua Tian; Xiaoqun Fang; Dzung Le; Jeffrey M Long; Bo Ma; Jamey D Marth; Nissi M Varki
A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins.
Glycobiology 2013;23(3):363-80.
2012: Elizabeth R Sturgill; Michael Tiemeyer; KATARINA VAJN; Won Ho Yang; Kazuhiro Aoki; Daniel Colacurcio; Marija Heffer; Pablo H H Lopez; Ileana Lorenzini; Senka Majić; Jamey D Marth; Ronald Schnaar
Biosynthesis of the major brain gangliosides GD1a and GT1b.
Glycobiology 2012;22(10):1289-301.
2012: Won Ho Yang; Prabhjit K Grewal; Jamey D Marth; Claudia Nussbaum; Markus Sperandio
Coordinated roles of ST3Gal-VI and ST3Gal-IV sialyltransferases in the synthesis of selectin ligands.
Blood 2012;120(5):1015-26.
2012: Camilla Luni; Jamey D Marth; Francis J Doyle
Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes.
PloS one 2012;7(12):e53130.
2011: Kazuaki Ohtsubo; Jerrold M Olefsky; Mark Z Chen; Jamey D Marth
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Nature medicine 2011;17(9):1067-75.
2011: Mohd Nazri Ismail; Erica L Stone; Maria Panico; Seung Ho Lee; Ying Luu; Kevin Ramirez; Samuel B Ho; Minoru Fukuda; Jamey D Marth; Stuart M Haslam; Anne Dell
High-sensitivity O-glycomic analysis of mice deficient in core 2 {beta}1,6-N-acetylglucosaminyltransferases.
Glycobiology 2011;21(1):82-98.
2010: Seung Ho Lee; Shin-Yi Yu; Jun Nakayama; Kai-Hooi Khoo; Erica L Stone; Michiko N Fukuda; Jamey D Marth; Minoru Fukuda
Core2 O-glycan structure is essential for the cell surface expression of sucrase isomaltase and dipeptidyl peptidase-IV during intestinal cell differentiation.
The Journal of biological chemistry 2010;285(48):37683-92.
2010: Shinobu Kitazume; Rie Imamaki; Kazuko Ogawa; Yusuke Komi; Satoshi Futakawa; Soichi Kojima; Yasuhiro Hashimoto; Jamey D Marth; James C Paulson; Naoyuki Taniguchi
Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling.
The Journal of biological chemistry 2010;285(9):6515-21.
2010: Shinji Takamatsu; Aristotelis Antonopoulos; Kazuaki Ohtsubo; David Ditto; Yasunori Chiba; Dzung T Le; Howard R Morris; Stuart M Haslam; Anne Dell; Jamey D Marth; Naoyuki Taniguchi
Physiological and glycomic characterization of N-acetylglucosaminyltransferase-IVa and -IVb double deficient mice.
Glycobiology 2010;20(4):485-97.
2009: Ajit Varki; Richard D Cummings; Jeffrey D Esko; Hudson H Freeze; Pamela Stanley; Jamey D Marth; Carolyn R Bertozzi; Gerald W Hart; Marilynn E Etzler
Symbol nomenclature for glycan representation.
Proteomics 2009;9(24):5398-9.
2009: Viktoria Rumjantseva; Prabhjit K Grewal; Hans Wandall; Emma C Josefsson; Anne Louise Sørensen; Göran Larson; Jamey D Marth; John H Hartwig; Karin M Hoffmeister
Dual roles for hepatic lectin receptors in the clearance of chilled platelets.
Nature medicine 2009;15(11):1273-80.
2009: Marty L Montpetit; Patrick J Stocker; Tara A Schwetz; Jean M Harper; Sarah A Norring; Lana Schaffer; Simon J North; Jihye Jang-Lee; Timothy Gilmartin; Steven R Head; Stuart M Haslam; Anne Dell; Jamey D Marth; Eric S Bennett
Regulated and aberrant glycosylation modulate cardiac electrical signaling.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(38):16517-22.
2009: Huan Wang; Weiyu Zhang; Rong Tang; Robert P Hebbel; M Anna Kowalska; Chunxiang Zhang; Jamey D Marth; Minoru Fukuda; Chuhong Zhu; Yuqing Huo
Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(7):1053-9.
2009: Erica L Stone; Mohd Nazri Ismail; Seung Ho Lee; Ying Luu; Kevin Ramirez; Stuart M Haslam; Samuel B Ho; Anne Dell; Minoru Fukuda; Jamey D Marth
Glycosyltransferase function in core 2-type protein O glycosylation.
Molecular and cellular biology 2009;29(13):3770-82.
2009: Huan Wang; Rong Tang; Weiyu Zhang; Karine Amirikian; Zhen Geng; Jianguo Geng; Robert P Hebbel; Lijun Xia; Jamey D Marth; Minoru Fukuda; Shigeki Katoh; Yuqing Huo
Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(2):180-7.
2008: Jamey D Marth; Prabhjit K Grewal
Mammalian glycosylation in immunity.
Nature reviews. Immunology 2008;8(11):874-87.
2008: Jamey D Marth
A unified vision of the building blocks of life.
Nature cell biology 2008;10(9):1015-6.
2008: David Frommhold; Andreas Ludwig; M Gabriele Bixel; Alexander Zarbock; Inna Babushkina; Melitta Weissinger; Sandra Cauwenberghs; Lesley G Ellies; Jamey D Marth; Annette G Beck-Sickinger; Michael Sixt; Bärbel Lange-Sperandio; Alma Zernecke; Ernst Brandt; Christian Weber; Dietmar Vestweber; Klaus Ley; Markus Sperandio
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
The Journal of experimental medicine 2008;205(6):1435-46.
2008: Prabhjit K Grewal; Satoshi Uchiyama; David Ditto; Nissi Varki; DT Le; Victor Nizet; Jamey D Marth
The Ashwell receptor mitigates the lethal coagulopathy of sepsis.
Nature medicine 2008;14(6):648-55.
2008: Lorna Santos; Kevin E Draves; Mark Boton; Prabhjit K Grewal; Jamey D Marth; Edward A Clark
Dendritic cell-dependent inhibition of B cell proliferation requires CD22.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(7):4561-9.
2007: Mari Tenno; Kazuaki Ohtsubo; Fred K Hagen; David Ditto; Alexander Zarbock; Patrick Schaerli; Ulrich H von Andrian; Klaus Ley; Dzung Le; Lawrence Tabak; Jamey D Marth
Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity.
Molecular and cellular biology 2007;27(24):8783-96.
2007: Ichiro Sugimoto; Satoshi Futakawa; Ritsuko Oka; Kazuko Ogawa; Jamey D Marth; Eiji Miyoshi; Naoyuki Taniguchi; Yasuhiro Hashimoto; Shinobu Kitazume
Beta-galactoside alpha2,6-sialyltransferase I cleavage by BACE1 enhances the sialylation of soluble glycoproteins. A novel regulatory mechanism for alpha2,6-sialylation.
The Journal of biological chemistry 2007;282(48):34896-903.
2007: Kiyohiko Angata; Valerie Huckaby; Barbara Ranscht; Alexey Terskikh; Jamey D Marth; Minoru Fukuda
Polysialic acid-directed migration and differentiation of neural precursors are essential for mouse brain development.
Molecular and cellular biology 2007;27(19):6659-68.
2007: Ryan Green; Erica L Stone; Mari Tenno; Eero Lehtonen; Marilyn G Farquhar; Jamey D Marth
Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis.
Immunity 2007;27(2):308-20.
2007: Joseph D Hernandez; Jeffrey Klein; Steven J Van Dyken; Jamey D Marth; Linda G Baum
T-cell activation results in microheterogeneous changes in glycosylation of CD45.
International immunology 2007;19(7):847-56.
2007: Junya Mitoma; Xingfeng Bao; Bronislawa Petryanik; Patrick Schaerli; Jean-Marc Gauguet; Shin-Yi Yu; Hiroto Kawashima; Hideo Saito; Kazuaki Ohtsubo; Jamey D Marth; Kay-Hooi Khoo; Ulrich H von Andrian; John B Lowe; Minoru Fukuda
Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment.
Nature immunology 2007;8(4):409-18.
2007: Steven J Van Dyken; Ryan Green; Jamey D Marth
Structural and mechanistic features of protein O glycosylation linked to CD8+ T-cell apoptosis.
Molecular and cellular biology 2007;27(3):1096-111.
2007: Kazuaki Ohtsubo; Jamey D Marth
Conditional mutagenesis of the genome using site-specific DNA recombination.
CSH protocols 2007;2007():pdb.top12.
2007: Kazuaki Ohtsubo; Jamey D Marth
Cre Recombinase Gene Transfer In Vitro and Detection of loxP-Dependent Recombination.
CSH protocols 2007;2007():pdb.prot4762.
2007: Kazuaki Ohtsubo; Jamey D Marth
Genome Modification by Inclusion of loxP Transgene Sequences.
CSH protocols 2007;2007():pdb.prot4761.
2006: Markus Sperandio; David Frommhold; Inna Babushkina; Lesley G Ellies; Timothy S Olson; Michael L Smith; Benedikt Fritzsching; Eva Pauly; David F Smith; Rainer Nobiling; Otwin Linderkamp; Jamey D Marth; Klaus Ley
Alpha 2,3-sialyltransferase-IV is essential for L-selectin ligand function in inflammation.
European journal of immunology 2006;36(12):3207-15.
2006: Bin Zheng; Tingdong Tang; Nan Tang; Krystyna Kudlicka; Kazuaki Ohtsubo; Phuong Ma; Jamey D Marth; Marilyn G Farquhar; Eero Lehtonen
Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16776-81.
2006: Megumi Hato; Hiroaki Nakagawa; Masaki Kurogochi; Tomoya O Akama; Jamey D Marth; Michiko N Fukuda; Shin-Ichiro Nishimura
Unusual N-glycan structures in alpha-mannosidase II/IIx double null embryos identified by a systematic glycomics approach based on two-dimensional LC mapping and matrix-dependent selective fragmentation method in MALDI-TOF/TOF mass spectrometry.
Molecular & cellular proteomics : MCP 2006;5(11):2146-57.
2006: Kazuaki Ohtsubo; Jamey D Marth
Glycosylation in cellular mechanisms of health and disease.
Cell 2006;126(5):855-67.
2006: Prabhjit K Grewal; Mark Boton; Kevin Ramirez; Brian E Collins; Akira Saito; Ryan Green; Kazuaki Ohtsubo; Daniel Chui; Jamey D Marth
ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.
Molecular and cellular biology 2006;26(13):4970-81.
2006: Tomoya O Akama; Hiroaki Nakagawa; Nyet Kui Wong; Mark Sutton-Smith; Anne Dell; Howard R Morris; Jun Nakayama; Shin-Ichiro Nishimura; Ashok Pai; Kelley W Moremen; Jamey D Marth; Michiko N Fukuda
Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):8983-8.
2006: Patrick J Brennan; Sandra J Saouaf; Steven J Van Dyken; Jamey D Marth; Bin LI; Avinash Bhandoola; Mark I Greene
Sialylation regulates peripheral tolerance in CD4+ T cells.
International immunology 2006;18(5):627-35.
2006: Kiyohiko Angata; Wenjau Lee; Junya Mitoma; Jamey D Marth; Minoru Fukuda
Cellular and molecular analysis of neural development of glycosyltransferase gene knockout mice.
Methods in enzymology 2006;417():25-37.
2005: Birgit Weinhold; Ralph Seidenfaden; Iris Röckle; Martina Mühlenhoff; Frank Schertzinger; Sidonie Conzelmann; Jamey D Marth; Rita Gerardy-Schahn; Herbert Hildebrandt
Genetic ablation of polysialic acid causes severe neurodevelopmental defects rescued by deletion of the neural cell adhesion molecule.
The Journal of biological chemistry 2005;280(52):42971-7.
2005: Kazuaki Ohtsubo; Shinji Takamatsu; Mari T Minowa; Aruto Yoshida; Makoto Takeuchi; Jamey D Marth
Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes.
Cell 2005;123(7):1307-21.
2005: Gregory H Underhill; Dimitrios G Zisoulis; K Pallav Kolli; Lesley G Ellies; Jamey D Marth; Geoffrey S Kansas
A crucial role for T-bet in selectin ligand expression in T helper 1 (Th1) cells.
Blood 2005;106(12):3867-73.
2004: Jean-Marc Gauguet; Steven D Rosen; Jamey D Marth; Ulrich H von Andrian
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes.
Blood 2004;104(13):4104-12.
2004: Shaolin Shi; Suzannah A Williams; Antti Seppo; Henry Kurniawan; Wei Chen; Zhengyi Ye; Jamey D Marth; Pamela Stanley
Inactivation of the Mgat1 gene in oocytes impairs oogenesis, but embryos lacking complex and hybrid N-glycans develop and implant.
Molecular and cellular biology 2004;24(22):9920-9.
2004: Petra May; Astrid Rohlmann; Hans H Bock; Kai Zurhove; Jamey D Marth; Eike D Schomburg; Jeffrey L Noebels; Uwe Beffert; J David Sweatt; Edwin J Weeber; Joachim Herz
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.
Molecular and cellular biology 2004;24(20):8872-83.
2004: Jamey D Marth
Unmasking connections in transmembrane immune signaling.
Nature immunology 2004;5(10):1008-10.
2004: Kiyohiko Angata; Jeffrey M Long; Olena Bukalo; Wenjau Lee; Alexander Dityatev; Anthony Wynshaw-Boris; Melitta Schachner; Minoru Fukuda; Jamey D Marth
Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior.
The Journal of biological chemistry 2004;279(31):32603-13.
2004: Natasha E Zachara; Niall O'Donnell; Win D Cheung; Jessica J Mercer; Jamey D Marth; Gerald W Hart
Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells.
The Journal of biological chemistry 2004;279(29):30133-42.
2004: Zhengyi Ye; Jamey D Marth
N-glycan branching requirement in neuronal and postnatal viability.
Glycobiology 2004;14(6):547-58.
2004: Brian E Collins; Ola Blixt; Alexis R DeSieno; Nicolai Bovin; Jamey D Marth; James C Paulson
Masking of CD22 by cis ligands does not prevent redistribution of CD22 to sites of cell contact.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(16):6104-9.
2004: Niall O'Donnell; Natasha E Zachara; Gerald W Hart; Jamey D Marth
Ogt-dependent X-chromosome-linked protein glycosylation is a requisite modification in somatic cell function and embryo viability.
Molecular and cellular biology 2004;24(4):1680-90.
2004: Nobuyoshi Hiraoka; Hiroto Kawashima; Bronislawa Petryniak; Jun Nakayama; Junya Mitoma; Jamey D Marth; John B Lowe; Minoru Fukuda
Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial venule-restricted sulfotransferase collaboratively control lymphocyte homing.
The Journal of biological chemistry 2004;279(4):3058-67.
2003: Anne Marie Moody; Simon J North; Bruce Reinhold; Steven J Van Dyken; Mark E Rogers; Maria Panico; Anne Dell; Howard R Morris; Jamey D Marth; Ellis L Reinherz
Sialic acid capping of CD8beta core 1-O-glycans controls thymocyte-major histocompatibility complex class I interaction.
The Journal of biological chemistry 2003;278(9):7240-6.
2003: Yan Zhang; Hiroko Iwasaki; Han Wang; Takashi Kudo; Timothy B Kalka; Thierry Hennet; Tomomi Kubota; Lamei Cheng; Niro Inaba; Masanori Gotoh; Akira Togayachi; Jianming Guo; Hisashi Hisatomi; Kazuyuki Nakajima; Shoko Nishihara; Mitsuru Nakamura; Jamey D Marth; Hisashi Narimatsu
Cloning and characterization of a new human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase, designated pp-GalNAc-T13, that is specifically expressed in neurons and synthesizes GalNAc alpha-serine/threonine antigen.
The Journal of biological chemistry 2003;278(1):573-84.
2003: John B Lowe; Jamey D Marth
A genetic approach to Mammalian glycan function.
Annual review of biochemistry 2003;72():643-91.
2002: Yan Wang; Harry Schachter; Jamey D Marth
Mice with a homozygous deletion of the Mgat2 gene encoding UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,2-N-acetylglucosaminyltransferase II: a model for congenital disorder of glycosylation type IIa.
Biochimica et biophysica acta 2002;1573(3):301-11.
2002: Lesley G Ellies; Markus Sperandio; Gregory H Underhill; James Yousif; Michael Smith; John J Priatel; Geoffrey S Kansas; Klaus Ley; Jamey D Marth
Sialyltransferase specificity in selectin ligand formation.
Blood 2002;100(10):3618-25.
2002: Laura T Martin; Jamey D Marth; Ajit Varki; Nissi M Varki
Genetically altered mice with different sialyltransferase deficiencies show tissue-specific alterations in sialylation and sialic acid 9-O-acetylation.
The Journal of biological chemistry 2002;277(36):32930-8.
2002: Brian E Collins; Ola Blixt; Nicolai V Bovin; Claus-Peter Danzer; Daniel Chui; Jamey D Marth; Lars Nitschke; James C Paulson
Constitutively unmasked CD22 on B cells of ST6Gal I knockout mice: novel sialoside probe for murine CD22.
Glycobiology 2002;12(9):563-71.
2002: Elisabeth Mertsching; Andrea L Wurster; Carol D Katayama; Jeffrey Esko; Fred Ramsdell; Jamey D Marth; Stephen M Hedrick
A mouse strain defective for alphabeta versus gammadelta T cell lineage commitment.
International immunology 2002;14(9):1039-53.
2002: Lesley G Ellies; David Ditto; Gallia G Levy; Mark Wahrenbrock; David Ginsburg; Ajit Varki; Dzung T Le; Jamey D Marth
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10042-7.
2002: Thandi M Onami; Meei Yun Lin; Dawne M Page; Shirley A Reynolds; Carol D Katayama; Jamey D Marth; Tatsuro Irimura; Ajit Varki; Nissi M Varki; Stephen M Hedrick
Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins.
Molecular and cellular biology 2002;22(14):5173-81.
2001: Y Wang; J Tan; Mark Sutton-Smith; David Ditto; Maria Panico; R M Campbell; Nissi M Varki; J M Long; J Jaeken; S R Levinson; A Wynshaw-Boris; Howard R Morris; D Le; Anne Dell; H Schachter; Jamey D Marth
Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis.
Glycobiology 2001;11(12):1051-70.
2001: Anne Marie Moody; Daniel Chui; Pedro A Reche; John J Priatel; Jamey D Marth; Ellis L Reinherz
Developmentally regulated glycosylation of the CD8alphabeta coreceptor stalk modulates ligand binding.
Cell 2001;107(4):501-12.
2001: Markus Sperandio; S Bradley Forlow; Jayant Thatte; Lesley G Ellies; Jamey D Marth; Klaus Ley
Differential requirements for core2 glucosaminyltransferase for endothelial L-selectin ligand function in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(4):2268-74.
2001: Jiunn-Chern Yeh; Nobuyoshi Hiraoka; Bronislawa Petryniak; Jun Nakayama; Lesley G Ellies; David Rabuka; Ole Hindsgaul; Jamey D Marth; John B Lowe; Michiko N Fukuda
Novel sulfated lymphocyte homing receptors and their control by a Core1 extension beta 1,3-N-acetylglucosaminyltransferase.
Cell 2001;105(7):957-69.
2001: Markus Sperandio; A Thatte; DS Foy; Lesley G Ellies; Jamey D Marth; Klaus Ley
Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice.
Blood 2001;97(12):3812-9.
2001: Karen R. Snapp; C E Heitzig; Lesley G Ellies; Jamey D Marth; Geoffrey S Kansas
Differential requirements for the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase in biosynthesis of ligands for E-selectin and P-selectin.
Blood 2001;97(12):3806-11.
2001: D Chui; G Sellakumar; Ryan Green; Mark Sutton-Smith; T McQuistan; KW Marek; H Morris; Anne Dell; Jamey D Marth
Genetic remodeling of protein glycosylation in vivo induces autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(3):1142-7.
2000: JR Marszalek; Xinran Liu; Elizabeth A Roberts; Daniel Chui; Jamey D Marth; David S Williams; Lawrence S B Goldstein
Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptors.
Cell 2000;102(2):175-87.
2000: Tak W Mak; Anne Hakem; John Peter McPherson; Amro Shehabeldin; E Zablocki; Eva Migon; Gordon S Duncan; Denis Bouchard; Andrew Wakeham; A Cheung; Jana Karaskova; Ildiko Sarosi; Jeremy Squire; Jamey D Marth; Raza Hakem
Brca1 required for T cell lineage development but not TCR loci rearrangement.
Nature immunology 2000;1(1):77-82.
2000: R Shafi; Sai Prasad N Iyer; Lesley G Ellies; Niall O'Donnell; KW Marek; Daniel Chui; Gerald W Hart; Jamey D Marth
The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(11):5735-9.
2000: John J Priatel; Daniel Chui; N Hiraoka; C J Simmons; K B Richardson; Dawne M Page; M Fukuda; Nissi M Varki; Jamey D Marth
The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis.
Immunity 2000;12(3):273-83.
1999: K W Marek; I K Vijay; Jamey D Marth
A recessive deletion in the GlcNAc-1-phosphotransferase gene results in peri-implantation embryonic lethality.
Glycobiology 1999;9(11):1263-71.
1998: Lesley G Ellies; Shigeru Tsuboi; Bronislawa Petryniak; John B Lowe; Michiko N Fukuda; Jamey D Marth
Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation.
Immunity 1998;9(6):881-90.
1998: Richard Boyd; Ivona Kozieradzki; Ann P Chidgey; HW Mittrücker; Denis Bouchard; E Timms; K Kishihara; Christopher J Ong; Daniel Chui; Jamey D Marth; Tak W Mak; Josef M Penninger
Receptor-specific allelic exclusion of TCRV alpha-chains during development.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1718-27.
1998: Thierry Hennet; Daniel Chui; James C Paulson; Jamey D Marth
Immune regulation by the ST6Gal sialyltransferase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(8):4504-9.
1997: Daniel Chui; M Oh-Eda; Yung-Feng Liao; K Panneerselvam; A Lal; KW Marek; H H Freeze; Kelley W Moremen; M N Fukuda; Jamey D Marth
Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis.
Cell 1997;90(1):157-67.
1997: Christopher J Ong; Jan P Dutz; Daniel Chui; Hung-Sia Teh; Jamey D Marth
CD45 enhances positive selection and is expressed at a high level in large, cycling, positively selected CD4+CD8+ thymocytes.
Immunology 1997;91(1):95-103.
1997: Ivona Kozieradzki; TM Kündig; K Kishihara; Christopher J Ong; D Chiu; V A Wallace; K Kawai; E Timms; J Ionescu; Pamela S Ohashi; Jamey D Marth; Tak W Mak; Josef M Penninger
T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(7):3130-9.
1997: John J Priatel; M Sarkar; H Schachter; Jamey D Marth
Isolation, characterization and inactivation of the mouse Mgat3 gene: the bisecting N-acetylglucosamine in asparagine-linked oligosaccharides appears dispensable for viability and reproduction.
Glycobiology 1997;7(1):45-56.
1996: Eldad Zacksenhaus; Z Jiang; D Chung; Jamey D Marth; R A Phillips; Brenda L Gallie
pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.
Genes & development 1996;10(23):3051-64.
1996: Jamey D Marth
Complexity in O-linked oligosaccharide biosynthesis engendered by multiple polypeptide N-acetylgalactosaminyltransferases.
Glycobiology 1996;6(7):701-5.
1996: Jamey D Marth
Recent advances in gene mutagenesis by site-directed recombination.
The Journal of clinical investigation 1996;97(9):1999-2002.
1996: D Phaneuf; N Wakamatsu; Jing-Qi Huang; A Borowski; Alan Peterson; S R Fortunato; G Ritter; Suleiman A Igdoura; Carlos R Morales; G Benoit; BR Akerman; Daniel Leclerc; N Hanai; Jamey D Marth; Jacquetta M Trasler; Roy A Gravel
Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases.
Human molecular genetics 1996;5(1):1-14.
1995: T Hennet; F K Hagen; Lawrence Tabak; Jamey D Marth
T-cell-specific deletion of a polypeptide N-acetylgalactosaminyl-transferase gene by site-directed recombination.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12070-4.
1995: Maria Granovsky; C Fode; Charles E Warren; R M Campbell; Jamey D Marth; James Michael Pierce; Nevis Fregien; James W Dennis
GlcNAc-transferase V and core 2 GlcNAc-transferase expression in the developing mouse embryo.
Glycobiology 1995;5(8):797-806.
1995: R M Campbell; M Metzler; Maria Granovsky; James W Dennis; Jamey D Marth
Complex asparagine-linked oligosaccharides in Mgat1-null embryos.
Glycobiology 1995;5(5):535-43.
1995: ME Lewis; I J Forsythe; Jamey D Marth; J D Brunzell; Michael R Hayden; R Keith Humphries
Retroviral-mediated gene transfer and expression of human lipoprotein lipase in somatic cells.
Human gene therapy 1995;6(7):853-63.
1995: Jamal Nasir; Stan B Floresco; John R O'Kusky; V M Diewert; Joy M Richman; J Zeisler; A Borowski; Jamey D Marth; Anthony G Phillips; Michael R Hayden
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes.
Cell 1995;81(5):811-23.
1995: Jan P Dutz; Christopher J Ong; Jamey D Marth; Hung-Sia Teh
Distinct differentiative stages of CD4+CD8+ thymocyte development defined by the lack of coreceptor binding in positive selection.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2588-99.
1995: Douglas A Carlow; Jamey D Marth; Ian Clark-Lewis; Hung-Sia Teh
Isolation of a gene encoding a developmentally regulated T cell-specific protein with a guanine nucleotide triphosphate-binding motif.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(4):1724-34.
1994: H Gu; Jamey D Marth; P C Orban; H Mossmann; Klaus Rajewsky
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting.
Science (New York, N.Y.) 1994;265(5168):103-6.
1994: M Metzler; A Gertz; Mohan Sarkar; Harry Schachter; J W Schrader; Jamey D Marth
Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development.
The EMBO journal 1994;13(9):2056-65.
1994: Christopher J Ong; Daniel Chui; Hung-Sia Teh; Jamey D Marth
Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(8):3793-805.
1994: Daniel Chui; Christopher J Ong; Pauline Johnson; Hung-Sia Teh; Jamey D Marth
Specific CD45 isoforms differentially regulate T cell receptor signaling.
The EMBO journal 1994;13(4):798-807.
1994: Jamey D Marth
Will the transgenic mouse serve as a Rosetta Stone to glycoconjugate function?
Glycoconjugate journal 1994;11(1):3-8.
1994: Jamey D Marth; Christopher J Ong; Daniel Chui
Specific CD45 isoforms regulate T cell ontogeny and are functionally distinct in modifying immune activation.
Advances in experimental medicine and biology 1994;365():149-66.
1992: P C Orban; Daniel Chui; Jamey D Marth
Tissue- and site-specific DNA recombination in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6861-5.
1992: S Pownall; C A Kozak; K Schappert; Mohan Sarkar; E Hull; Harry Schachter; Jamey D Marth
Molecular cloning and characterization of the mouse UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene.
Genomics 1992;12(4):699-704.
1992: Julian D Watts; G M Wilson; E Ettenhadieh; Ian Clark-Lewis; C A Kubanek; Caroline R Astell; Jamey D Marth; Ruedi Aebersold
Purification and initial characterization of the lymphocyte-specific protein-tyrosyl kinase p56lck from a baculovirus expression system.
The Journal of biological chemistry 1992;267(2):901-7.
1991: KM Abraham; Steven D Levin; Jamey D Marth; Katherine Forbush; Roger M Perlmutter
Delayed thymocyte development induced by augmented expression of p56lck.
The Journal of experimental medicine 1991;173(6):1421-32.
1991: KM Abraham; Steven D Levin; Jamey D Marth; Katherine Forbush; Roger M Perlmutter
Thymic tumorigenesis induced by overexpression of p56lck.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(9):3977-81.
1989: Jamey D Marth; David B Lewis; M P Cooke; E D Mellins; M E Gearn; L E Samelson; C B Wilson; A D Miller; Roger M Perlmutter
Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck).
Journal of immunology (Baltimore, Md. : 1950) 1989;142(7):2430-7.
1989: Roger M Perlmutter; Jamey D Marth; Steven F Ziegler; A M Garvin; S Pawar; M P Cooke; KM Abraham
Specialized protein tyrosine kinase proto-oncogenes in hematopoietic cells.
Biochimica et biophysica acta 1989;948(3):245-62.
1988: R R Louie; C S King; A MacAuley; Jamey D Marth; R M Perlmutter; W Eckhart; Jonathan A Cooper
p56lck protein-tyrosine kinase is cytoskeletal and does not bind to polyomavirus middle T antigen.
Journal of virology 1988;62(12):4673-9.
1988: Roger M Perlmutter; Jamey D Marth; David B Lewis; R Peet; Steven F Ziegler; C B Wilson
Structure and expression of lck transcripts in human lymphoid cells.
Journal of cellular biochemistry 1988;38(2):117-26.
1988: A M Garvin; S Pawar; Jamey D Marth; Roger M Perlmutter
Structure of the murine lck gene and its rearrangement in a murine lymphoma cell line.
Molecular and cellular biology 1988;8(8):3058-64.
1988: Jamey D Marth; R W Overell; K E Meier; Edwin G Krebs; Roger M Perlmutter
Translational activation of the lck proto-oncogene.
Nature 1988;332(6160):171-3.
1988: Jamey D Marth; J A Cooper; C S King; Steven F Ziegler; D A Tinker; R W Overell; Edwin G Krebs; Roger M Perlmutter
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck).
Molecular and cellular biology 1988;8(2):540-50.
1987: Jamey D Marth; David B Lewis; C B Wilson; M E Gearn; Edwin G Krebs; Roger M Perlmutter
Regulation of pp56lck during T-cell activation: functional implications for the src-like protein tyrosine kinases.
The EMBO journal 1987;6(9):2727-34.
1987: Steven F Ziegler; Jamey D Marth; David B Lewis; Roger M Perlmutter
Novel protein-tyrosine kinase gene (hck) preferentially expressed in cells of hematopoietic origin.
Molecular and cellular biology 1987;7(6):2276-85.
1985: Jamey D Marth; R Peet; Edwin G Krebs; Roger M Perlmutter
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.
Cell 1985;43(2 Pt 1):393-404.