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Billy Martin
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50
Wiley, Jenny
42
Razdan, Raj
42
Damaj, Imad
41
Compton, DR
34
Lichtman, Aron
21
Huffman, John
19
Abood, Mary
17
Thomas, Brian
16
Glennon, Richard
11
Griffin, Graeme
11
Balster, Robert
11
Mahadevan, Anu
10
Welch, Sandra
10
Aceto, Mario
10
Delorenzo, Robert
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All Publications
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2009: Jackson Kia J; Walters Carrie L; Miles Michael F; Martin Billy R; Damaj M Imad
Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice.
Neuropharmacology 2009;57(4):347-55.
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2009: Blair Robert E; Deshpande Laxmikant S; Sombati Sompong; Elphick Maurice R; Martin Billy R; DeLorenzo Robert J
Prolonged exposure to WIN55,212-2 causes downregulation of the CB1 receptor and the development of tolerance to its anticonvulsant effects in the hippocampal neuronal culture model of acquired epilepsy.
Neuropharmacology 2009;57(3):208-18.
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2009: Vann Robert E; Warner Jonathan A; Bushell Kristen; Huffman John W; Martin Billy R; Wiley Jenny L
Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice.
European journal of pharmacology 2009;615(1-3):102-7.
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2009: Jackson K J; Kota D H; Martin B R; Damaj M I
The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion.
Neuropharmacology 2009;56(6-7):970-4.
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2009: Falenski Katherine W; Carter Dawn S; Harrison Anne J; Martin Billy R; Blair Robert E; DeLorenzo Robert J
Temporal characterization of changes in hippocampal cannabinoid CB(1) receptor expression following pilocarpine-induced status epilepticus.
Brain research 2009;1262():64-72.
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2008: Abdrakhmanova Galya R; Carroll F Ivy; Damaj M I; Martin Billy R
3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs.
Neuropharmacology 2008;55(8):1287-92.
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2008: Merritt Lisa L; Martin B R; Walters C; Lichtman A H; Damaj M Imad
The endogenous cannabinoid system modulates nicotine reward and dependence.
The Journal of pharmacology and experimental therapeutics 2008;326(2):483-92.
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2008: Kota D; Martin B R; Damaj M I
Age-dependent differences in nicotine reward and withdrawal in female mice.
Psychopharmacology 2008;198(2):201-10.
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2008: Raborn Erinn S; Marciano-Cabral Francine; Buckley Nancy E; Martin Billy R; Cabral Guy A
The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2008;3(2):117-29.
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2008: Vann Robert E; Gamage Thomas F; Warner Jonathan A; Marshall Ericka M; Taylor Nathan L; Martin Billy R; Wiley Jenny L
Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol.
Drug and alcohol dependence 2008;94(1-3):191-8.
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2008: Jackson K J; Martin B R; Changeux J P; Damaj M I
Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs.
The Journal of pharmacology and experimental therapeutics 2008;325(1):302-12.
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2008: McKinney Diana L; Cassidy Michael P; Collier Lauren M; Martin Billy R; Wiley Jenny L; Selley Dana E; Sim-Selley Laura J
Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol.
The Journal of pharmacology and experimental therapeutics 2008;324(2):664-73.
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2008: Huffman John W; Thompson Alicia L S; Wiley Jenny L; Martin Billy R
Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.
Bioorganic & medicinal chemistry 2008;16(1):322-35.
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2007: Niyuhire Floride; Varvel Stephen A; Martin Billy R; Lichtman Aron H
Exposure to marijuana smoke impairs memory retrieval in mice.
The Journal of pharmacology and experimental therapeutics 2007;322(3):1067-75.
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2007: Varvel Stephen A; Martin Billy R; Lichtman Aron H
Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine.
Psychopharmacology 2007;193(4):511-9.
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2007: Kota D; Martin B R; Robinson S E; Damaj M I
Nicotine dependence and reward differ between adolescent and adult male mice.
The Journal of pharmacology and experimental therapeutics 2007;322(1):399-407.
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2007: Damaj M I; Fonck C; Marks M J; Deshpande P; Labarca C; Lester H A; Collins A C; Martin B R
Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice.
The Journal of pharmacology and experimental therapeutics 2007;321(3):1161-9.
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2007: Falenski K W; Blair R E; Sim-Selley L J; Martin B R; DeLorenzo R J
Status epilepticus causes a long-lasting redistribution of hippocampal cannabinoid type 1 receptor expression and function in the rat pilocarpine model of acquired epilepsy.
Neuroscience 2007;146(3):1232-44.
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2007: Naidu Pattipati S; Varvel Stephen A; Ahn Kyunghye; Cravatt Benjamin F; Martin Billy R; Lichtman Aron H
Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality.
Psychopharmacology 2007;192(1):61-70.
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2007: Deshpande Laxmikant S; Blair Robert E; Nagarkatti Nisha; Sombati Sompong; Martin Billy R; DeLorenzo Robert J
Development of pharmacoresistance to benzodiazepines but not cannabinoids in the hippocampal neuronal culture model of status epilepticus.
Experimental neurology 2007;204(2):705-13.
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2007: Deshpande Laxmikant S; Blair Robert E; Ziobro Julie M; Sombati Sompong; Martin Billy R; DeLorenzo Robert J
Endocannabinoids block status epilepticus in cultured hippocampal neurons.
European journal of pharmacology 2007;558(1-3):52-9.
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2007: Wise Laura E; Shelton Christopher C; Cravatt Benjamin F; Martin Billy R; Lichtman Aron H
Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors.
European journal of pharmacology 2007;557(1):44-8.
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2007: Vann Robert E; Cook Charles D; Martin Billy R; Wiley Jenny L
Cannabimimetic properties of ajulemic acid.
The Journal of pharmacology and experimental therapeutics 2007;320(2):678-86.
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2007: Deshpande Laxmikant S; Sombati Sompong; Blair Robert E; Carter Dawn S; Martin Billy R; DeLorenzo Robert J
Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy.
Neuroscience letters 2007;411(1):11-6.
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2007: Damaj M I; Siu E C K; Sellers E M; Tyndale R F; Martin B R
Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice.
The Journal of pharmacology and experimental therapeutics 2007;320(1):250-7.
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2006: Wiley Jenny L; Razdan Raj K; Martin Billy R
Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice.
Life sciences 2006;80(1):24-35.
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2006: Huffman John W; Padgett Lea W; Isherwood Matthew L; Wiley Jenny L; Martin Billy R
1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors.
Bioorganic & medicinal chemistry letters 2006;16(20):5432-5.
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2006: Wilson David M; Varvel Stephan A; Harloe John P; Martin Billy R; Lichtman Aron H
SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice.
Pharmacology, biochemistry, and behavior 2006;85(1):105-13.
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2006: Sim-Selley Laura J; Schechter Nicole S; Rorrer W Kirk; Dalton George D; Hernandez Jerry; Martin Billy R; Selley Dana E
Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration.
Molecular pharmacology 2006;70(3):986-96.
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2006: Martin Billy R; Wiley Jenny L; Beletskaya Irina; Sim-Selley Laura J; Smith Forrest L; Dewey William L; Cottney Jean; Adams Julia; Baker James; Hill David; Saha Bijali; Zerkowski John; Mahadevan Anu; Razdan Raj K
Pharmacological characterization of novel water-soluble cannabinoids.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1230-9.
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2006: Damaj M Imad; Zheng Jianfeng; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain.
Peptides 2006;27(8):2019-23.
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2006: Varvel S A; Wiley J L; Yang R; Bridgen D T; Long K; Lichtman A H; Martin B R
Interactions between THC and cannabidiol in mouse models of cannabinoid activity.
Psychopharmacology 2006;186(2):226-34.
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2006: Abdrakhmanova Galya R; Damaj M Imad; Carroll F Ivy; Martin Billy R
2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs.
Molecular pharmacology 2006;69(6):1945-52.
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2006: Blair Robert E; Deshpande Laxmikant S; Sombati Sompong; Falenski Katherine W; Martin Billy R; DeLorenzo Robert J
Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1072-8.
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2006: Marriott Karla-Sue C; Huffman John W; Wiley Jenny L; Martin Billy R
Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor.
Bioorganic & medicinal chemistry 2006;14(7):2386-97.
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2006: Grabus Sheri D; Martin Billy R; Brown Sharon E; Damaj M Imad
Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists.
Psychopharmacology 2006;184(3-4):456-63.
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2006: Ligresti Alessia; Cascio Maria Grazia; Pryce Gareth; Kulasegram Sanjitha; Beletskaya Irina; De Petrocellis Luciano; Saha Bijali; Mahadevan Anu; Visintin Cristina; Wiley Jenny L; Baker David; Martin Billy R; Razdan Raj K; Di Marzo Vincenzo
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis.
British journal of pharmacology 2006;147(1):83-91.
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2006: Huffman John W; Bushell Simon M; Joshi Sudhir N; Wiley Jenny L; Martin Billy R
Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
Bioorganic & medicinal chemistry 2006;14(1):247-62.
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2006: Marciano-Cabral Francine; Raborn Erinn S; Martin Billy R; Cabral Guy A
Delta-9-tetrahydrocannabinol, the major psychoactive component in marijuana, inhibits macrophage chemotaxis to Acanthamoeba.
The Journal of eukaryotic microbiology 2006;53 Suppl 1():S15-7.
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2005: Damaj M Imad; Wiley Jenny L; Martin Billy R; Papke Roger L
In vivo characterization of a novel inhibitor of CNS nicotinic receptors.
European journal of pharmacology 2005;521(1-3):43-8.
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2005: Huffman John W; Szklennik Paul V; Almond Amanda; Bushell Kristen; Selley Dana E; He Hengjun; Cassidy Michael P; Wiley Jenny L; Martin Billy R
1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles.
Bioorganic & medicinal chemistry letters 2005;15(18):4110-3.
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2005: Martin Billy R
Role of lipids and lipid signaling in the development of cannabinoid tolerance.
Life sciences 2005;77(14):1543-58.
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2005: Varvel S A; Bridgen D T; Tao Q; Thomas B F; Martin B R; Lichtman A H
Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice.
The Journal of pharmacology and experimental therapeutics 2005;314(1):329-37.
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2005: Wiley Jenny L; Burston James J; Leggett Darnica C; Alekseeva Olga O; Razdan Raj K; Mahadevan Anu; Martin Billy R
CB1 cannabinoid receptor-mediated modulation of food intake in mice.
British journal of pharmacology 2005;145(3):293-300.
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2005: Grabus Sheri D; Martin Billy R; Imad Damaj M
Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.
European journal of pharmacology 2005;515(1-3):90-3.
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2005: Grabus Sheri D; Martin Billy R; Batman Angela M; Tyndale Rachel F; Sellers Edward; Damaj M Imad
Nicotine physical dependence and tolerance in the mouse following chronic oral administration.
Psychopharmacology 2005;178(2-3):183-92.
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2005: Damaj M I; Flood P; Ho K K; May E L; Martin B R
Effect of dextrometorphan and dextrorphan on nicotine and neuronal nicotinic receptors: in vitro and in vivo selectivity.
The Journal of pharmacology and experimental therapeutics 2005;312(2):780-5.
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2005: Huffman John W; Zengin Gulay; Wu Ming-Jung; Lu Jianzhong; Hynd George; Bushell Kristen; Thompson Alicia L S; Bushell Simon; Tartal Cindy; Hurst Dow P; Reggio Patricia H; Selley Dana E; Cassidy Michael P; Wiley Jenny L; Martin Billy R
Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists.
Bioorganic & medicinal chemistry 2005;13(1):89-112.
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2005: Lichtman A H; Martin B R
Cannabinoid tolerance and dependence.
Handbook of experimental pharmacology 2005;(168):691-717.
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2004: Selley Dana E; Cassidy Michael P; Martin Billy R; Sim-Selley Laura J
Long-term administration of Delta9-tetrahydrocannabinol desensitizes CB1-, adenosine A1-, and GABAB-mediated inhibition of adenylyl cyclase in mouse cerebellum.
Molecular pharmacology 2004;66(5):1275-84.
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2004: Damaj M Imad; Hunter Richard G; Martin Billy R; Kuhar Michael J
Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice.
Brain research 2004;1024(1-2):146-9.
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2004: Damaj M Imad; Carroll F Ivy; Eaton J Brek; Navarro Hernan A; Blough Bruce E; Mirza Sadiq; Lukas Ronald J; Martin Billy R
Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors.
Molecular pharmacology 2004;66(3):675-82.
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2004: Wiley Jenny L; LaVecchia Kari L; Karp Natalie E; Kulasegram Sanjitha; Mahadevan Anu; Razdan Raj K; Martin Billy R
A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats.
Experimental and clinical psychopharmacology 2004;12(3):173-9.
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2004: Bass Caroline E; Welch Sandra P; Martin Billy R
Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors.
European journal of pharmacology 2004;496(1-3):99-108.
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2004: Martin Billy R; Wiley Jenny L
Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain.
The journal of supportive oncology 2004;2(4):305-14; discussion 314-6.
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2004: Dukat Malgorzata; Taroua Mohamed; Dahdouh Abdelaziz; Siripurapu Umamaheswar; Damaj M Imad; Martin Billy R; Glennon Richard A
(+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.
Bioorganic & medicinal chemistry letters 2004;14(14):3651-4.
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2004: Martin Billy R; Sim-Selley Laura J; Selley Dana E
Signaling pathways involved in the development of cannabinoid tolerance.
Trends in pharmacological sciences 2004;25(6):325-30.
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2004: Baskfield Cassandra Y; Martin Billy R; Wiley Jenny L
Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice.
The Journal of pharmacology and experimental therapeutics 2004;309(1):86-91.
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2004: Dogruer Deniz; Lee Mase; Dukat Malgorzata; Damaj M Imad; Martin Billy R; Glennon Richard A
3-(4-Aminobutyn-1-yl)pyridines: binding at alpha 4 beta 2 nicotinic cholinergic receptors.
Bioorganic & medicinal chemistry letters 2004;14(2):523-6.
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2003: Damaj M I; Kao W; Martin B R
Characterization of spontaneous and precipitated nicotine withdrawal in the mouse.
The Journal of pharmacology and experimental therapeutics 2003;307(2):526-34.
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2003: Wallace Melisa J; Blair Robert E; Falenski Katherine W; Martin Billy R; DeLorenzo Robert J
The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy.
The Journal of pharmacology and experimental therapeutics 2003;307(1):129-37.
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2003: Simsek Rahime; Chang-Fong Jean; Lee Mase; Dukat Malgorzata; Imad Damaj M; Martin Billy R; Glennon Richard A
Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents.
Bioorganic & medicinal chemistry letters 2003;13(17):2917-20.
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2003: Damaj M Imad; Martin Billy R; Kuhar Michael J
Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice.
Brain research 2003;983(1-2):233-6.
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2003: Wiley Jenny L; Martin Billy R
Cannabinoid pharmacological properties common to other centrally acting drugs.
European journal of pharmacology 2003;471(3):185-93.
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2003: Huffman John W; Miller John R A; Liddle John; Yu Shu; Thomas Brian F; Wiley Jenny L; Martin Billy R
Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols.
Bioorganic & medicinal chemistry 2003;11(7):1397-410.
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2003: Ferretti G; Dukat M; Giannella M; Piergentili A; Pigini M; Quaglia W; Damaj M I; Martin B R; Glennon R A
Binding of nicotine and homoazanicotine analogues at neuronal nicotinic acetylcholinergic (nACh) receptors.
Bioorganic & medicinal chemistry letters 2003;13(4):733-5.
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2003: Huffman John W; Mabon Ross; Wu Ming Jung; Lu Jianzhong; Hart Richard; Hurst Dow P; Reggio Patricia H; Wiley Jenny L; Martin Billy R
3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor.
Bioorganic & medicinal chemistry 2003;11(4):539-49.
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2003: Breivogel Christopher S; Scates Susan M; Beletskaya Irina O; Lowery Olivia B; Aceto Mario D; Martin Billy R
The effects of delta9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors.
European journal of pharmacology 2003;459(2-3):139-50.
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2003: Darmani Nissar A; Sim-Selley Laura J; Martin Billy R; Janoyan Jano J; Crim Jennifer L; Parekh Bavita; Breivogel Christopher S
Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation.
European journal of pharmacology 2003;459(1):83-95.
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2002: Wiley Jenny L; Martin Billy R
Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes.
Chemistry and physics of lipids 2002;121(1-2):57-63.
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2002: Huffman John W; Bushell Simon M; Miller John R A; Wiley Jenny L; Martin Billy R
1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor.
Bioorganic & medicinal chemistry 2002;10(12):4119-29.
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2002: Bass Caroline E; Griffin Graeme; Grier Mark; Mahadevan Anu; Razdan Raj K; Martin Billy R
SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study.
Pharmacology, biochemistry, and behavior 2002;74(1):31-40.
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2002: Lichtman Aron H; Martin Billy R
Marijuana withdrawal syndrome in the animal model.
Journal of clinical pharmacology 2002;42(11 Suppl):20S-27S.
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2002: Wallace Melisa J; Martin Billy R; DeLorenzo Robert J
Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity.
European journal of pharmacology 2002;452(3):295-301.
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2002: Dukat Malgorzata; El-Zahabi Mohamed; Ferretti Giovanni; Damaj M Imad; Martin Billy R; Young Richard; Glennon Richard A
(-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine.
Bioorganic & medicinal chemistry letters 2002;12(20):3005-7.
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2002: Sim-Selley Laura J; Martin Billy R
Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice.
The Journal of pharmacology and experimental therapeutics 2002;303(1):36-44.
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2002: Wiley Jenny L; Jefferson Reneé G; Griffin Graeme; Liddle John; Yu Shu; Huffman John W; Martin Billy R
Paradoxical pharmacological effects of deoxy-tetrahydrocannabinol analogs lacking high CB1 receptor affinity.
Pharmacology 2002;66(2):89-99.
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2002: McKallip Robert J; Lombard Catherine; Martin Billy R; Nagarkatti Mitzi; Nagarkatti Prakash S
Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 2002;302(2):451-65.
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2002: Wilson David M; Peart Joanne; Martin Billy R; Bridgen D Troy; Byron Peter R; Lichtman Aron H
Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler.
Drug and alcohol dependence 2002;67(3):259-67.
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2002: Martin Billy R
Medical marijuana--moving beyond the smoke.
Lancet 2002;360(9326):4-5.
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2002: McKallip Robert J; Lombard Catherine; Fisher Michael; Martin Billy R; Ryu Seongho; Grant Steven; Nagarkatti Prakash S; Nagarkatti Mitzi
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease.
Blood 2002;100(2):627-34.
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2002: Howlett A C; Barth F; Bonner T I; Cabral G; Casellas P; Devane W A; Felder C C; Herkenham M; Mackie K; Martin B R; Mechoulam R; Pertwee R G
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors.
Pharmacological reviews 2002;54(2):161-202.
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2002: Martin Billy R
Identification of the endogenous cannabinoid system through integrative pharmacological approaches.
The Journal of pharmacology and experimental therapeutics 2002;301(3):790-6.
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2002: Wiley Jenny L; Lavecchia Kari L; Martin Billy R; Damaj M Imad
Nicotine-like discriminative stimulus effects of bupropion in rats.
Experimental and clinical psychopharmacology 2002;10(2):129-35.
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2002: Wiley Jenny L; Beletskaya Irina D; Ng Edward W; Dai Zongmin; Crocker Peter J; Mahadevan Anu; Razdan Raj K; Martin Billy R
Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists.
The Journal of pharmacology and experimental therapeutics 2002;301(2):679-89.
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2002: Di Marzo Vincenzo; Griffin Graeme; De Petrocellis Luciano; Brandi Ines; Bisogno Tiziana; Williams William; Grier Mark C; Kulasegram Sanjitha; Mahadevan Anu; Razdan Raj K; Martin Billy R
A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid.
The Journal of pharmacology and experimental therapeutics 2002;300(3):984-91.
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2002: Lichtman A H; Varvel S A; Martin B R
Endocannabinoids in cognition and dependence.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(2-3):269-85.
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2002: Dukat Malgorzata; Damaj Imad M; Young Richard; Vann Robert; Collins Allan C; Marks Michael J; Martin Billy R; Glennon Richard A
Functional diversity among 5-substituted nicotine analogs; in vitro and in vivo investigations.
European journal of pharmacology 2002;435(2-3):171-80.
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2002: Martin Billy R; Jefferson Renee G; Winckler Ramona; Wiley Jenny L; Thomas Brian F; Crocker Peter J; Williams William; Razdan Raj K
Assessment of structural commonality between tetrahydrocannabinol and anandamide.
European journal of pharmacology 2002;435(1):35-42.
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2001: Huffman J W; Lu J; Hynd G; Wiley J L; Martin B R
A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor.
Bioorganic & medicinal chemistry 2001;9(11):2863-70.
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2001: Wallace M J; Wiley J L; Martin B R; DeLorenzo R J
Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects.
European journal of pharmacology 2001;428(1):51-7.
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2001: Lichtman A H; Sheikh S M; Loh H H; Martin B R
Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice.
The Journal of pharmacology and experimental therapeutics 2001;298(3):1007-14.
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2001: Breivogel C S; Griffin G; Di Marzo V; Martin B R
Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.
Molecular pharmacology 2001;60(1):155-63.
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2001: Lichtman A H; Poklis J L; Poklis A; Wilson D M; Martin B R
The pharmacological activity of inhalation exposure to marijuana smoke in mice.
Drug and alcohol dependence 2001;63(2):107-16.
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2001: Lichtman A H; Fisher J; Martin B R
Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine.
Pharmacology, biochemistry, and behavior 2001;69(1-2):181-8.
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2001: Selley D E; Rorrer W K; Breivogel C S; Zimmer A M; Zimmer A; Martin B R; Sim-Selley L J
Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G-protein activation.
Journal of neurochemistry 2001;77(4):1048-57.
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2001: Wiley J L; Jefferson R G; Grier M C; Mahadevan A; Razdan R K; Martin B R
Novel pyrazole cannabinoids: insights into CB(1) receptor recognition and activation.
The Journal of pharmacology and experimental therapeutics 2001;296(3):1013-22.
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2001: Di Marzo V; Bisogno T; De Petrocellis L; Brandi I; Jefferson R G; Winckler R L; Davis J B; Dasse O; Mahadevan A; Razdan R K; Martin B R
Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands.
Biochemical and biophysical research communications 2001;281(2):444-51.
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2001: Griffin G; Williams S; Aung M M; Razdan R K; Martin B R; Abood M E
Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues.
British journal of pharmacology 2001;132(2):525-35.
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2000: Di Marzo V; Breivogel C S; Tao Q; Bridgen D T; Razdan R K; Zimmer A M; Zimmer A; Martin B R
Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain.
Journal of neurochemistry 2000;75(6):2434-44.
-
2000: Damaj M I; Meyer E M; Martin B R
The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model.
Neuropharmacology 2000;39(13):2785-91.
-
2000: Di Marzo V; Breivogel C; Bisogno T; Melck D; Patrick G; Tao Q; Szallasi A; Razdan R K; Martin B R
Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide.
European journal of pharmacology 2000;406(3):363-74.
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2000: Mahadevan A; Siegel C; Martin B R; Abood M E; Beletskaya I; Razdan R K
Novel cannabinol probes for CB1 and CB2 cannabinoid receptors.
Journal of medicinal chemistry 2000;43(20):3778-85.
-
2000: Slemmer J E; Martin B R; Damaj M I
Bupropion is a nicotinic antagonist.
The Journal of pharmacology and experimental therapeutics 2000;295(1):321-7.
-
2000: Martin B R; Beletskaya I; Patrick G; Jefferson R; Winckler R; Deutsch D G; Di Marzo V; Dasse O; Mahadevan A; Razdan R K
Cannabinoid properties of methylfluorophosphonate analogs.
The Journal of pharmacology and experimental therapeutics 2000;294(3):1209-18.
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2000: Wiley J L; Dewey M A; Jefferson R G; Winckler R L; Bridgen D T; Willoughby K A; Martin B R
Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects.
Life sciences 2000;67(13):1573-83.
-
2000: Aung M M; Griffin G; Huffman J W; Wu M; Keel C; Yang B; Showalter V M; Abood M E; Martin B R
Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding.
Drug and alcohol dependence 2000;60(2):133-40.
-
2000: Bass C E; Martin B R
Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice.
Drug and alcohol dependence 2000;60(2):113-9.
-
2000: Lichtman A H; Peart J; Poklis J L; Bridgen D T; Razdan R K; Wilson D M; Poklis A; Meng Y; Byron P R; Martin B R
Pharmacological evaluation of aerosolized cannabinoids in mice.
European journal of pharmacology 2000;399(2-3):141-9.
-
2000: Wiley J L; Patrick G S; Crocker P C; Saha B; Razdan R K; Martin B R
Antinociceptive effects of tetrahydrocannabinol side chain analogs: dependence upon route of administration.
European journal of pharmacology 2000;397(2-3):319-26.
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2000: Huffman J W; Lu J; Dai D; Kitaygorodskiy A; Wiley J L; Martin B R
Synthesis and pharmacology of a hybrid cannabinoid.
Bioorganic & medicinal chemistry 2000;8(2):439-47.
-
2000: Beardsley P M; Martin B R
Effects of the cannabinoid CB(1) receptor antagonist, SR141716A, after Delta(9)-tetrahydrocannabinol withdrawal.
European journal of pharmacology 2000;387(1):47-53.
-
2000: Keimowitz A R; Martin B R; Razdan R K; Crocker P J; Mascarella S W; Thomas B F
QSAR analysis of Delta(8)-THC analogues: relationship of side-chain conformation to cannabinoid receptor affinity and pharmacological potency.
Journal of medicinal chemistry 2000;43(1):59-70.
-
1999: Huffman J W; Liddle J; Yu S; Aung M M; Abood M E; Wiley J L; Martin B R
3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor.
Bioorganic & medicinal chemistry 1999;7(12):2905-14.
-
1999: Damaj M I; Glassco W; Dukat M; Martin B R
Pharmacological characterization of nicotine-induced seizures in mice.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1284-91.
-
1999: Járai Z; Wagner J A; Varga K; Lake K D; Compton D R; Martin B R; Zimmer A M; Bonner T I; Buckley N E; Mezey E; Razdan R K; Zimmer A; Kunos G
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):14136-41.
-
1999: Wiley J L; Martin B R
Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination.
Pharmacology, biochemistry, and behavior 1999;64(3):519-22.
-
1999: Griffin G; Wray E J; Martin B R; Abood M E
Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum.
British journal of pharmacology 1999;128(3):684-8.
-
1999: Damaj M I; Glassco W; Aceto M D; Martin B R
Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist.
The Journal of pharmacology and experimental therapeutics 1999;291(1):390-8.
-
1999: Martin B R; Jefferson R; Winckler R; Wiley J L; Huffman J W; Crocker P J; Saha B; Razdan R K
Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists.
The Journal of pharmacology and experimental therapeutics 1999;290(3):1065-79.
-
1999: Di Marzo V; Bisogno T; De Petrocellis L; Melck D; Martin B R
Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids.
Current medicinal chemistry 1999;6(8):721-44.
-
1999: Griffin G; Wray E J; Tao Q; McAllister S D; Rorrer W K; Aung M M; Martin B R; Abood M E
Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system.
European journal of pharmacology 1999;377(1):117-25.
-
1999: Ng E W; Aung M M; Abood M E; Martin B R; Razdan R K
Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas.
Journal of medicinal chemistry 1999;42(11):1975-81.
-
1999: Damaj M I; Slemmer J E; Carroll F I; Martin B R
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
The Journal of pharmacology and experimental therapeutics 1999;289(3):1229-36.
-
1999: Griffin G; Wray E J; Rorrer W K; Crocker P J; Ryan W J; Saha B; Razdan R K; Martin B R; Abood M E
An investigation into the structural determinants of cannabinoid receptor ligand efficacy.
British journal of pharmacology 1999;126(7):1575-84.
-
1999: Meng Y; Dukat M; Bridgen D T; Martin B R; Lichtman A H
Pharmacological effects of methamphetamine and other stimulants via inhalation exposure.
Drug and alcohol dependence 1999;53(2):111-20.
-
1999: Martin B R; Mechoulam R; Razdan R K
Discovery and characterization of endogenous cannabinoids.
Life sciences 1999;65(6-7):573-95.
-
1998: Martin B R; Lichtman A H
Cannabinoid transmission and pain perception.
Neurobiology of disease 1998;5(6 Pt B):447-61.
-
1998: Huffman J W; Liddle J; Duncan S G; Yu S; Martin B R; Wiley J L
Synthesis and pharmacology of the isomeric methylheptyl-delta8-tetrahydrocannabinols.
Bioorganic & medicinal chemistry 1998;6(12):2383-96.
-
1998: Aceto M D; Scates S M; Razdan R K; Martin B R
Anandamide, an endogenous cannabinoid, has a very low physical dependence potential.
The Journal of pharmacology and experimental therapeutics 1998;287(2):598-605.
-
1998: Singer M; Ryan W J; Saha B; Martin B R; Razdan R K
Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol.
Journal of medicinal chemistry 1998;41(22):4400-7.
-
1998: Lichtman A H; Wiley J L; LaVecchia K L; Neviaser S T; Arthur D B; Wilson D M; Martin B R
Effects of SR 141716A after acute or chronic cannabinoid administration in dogs.
European journal of pharmacology 1998;357(2-3):139-48.
-
1998: Liddle J; Huffman J W; Wiley J L; Martin B R
Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC.
Bioorganic & medicinal chemistry letters 1998;8(16):2223-6.
-
1998: Wiley J L; Ryan W J; Razdan R K; Martin B R
Evaluation of cannabimimetic effects of structural analogs of anandamide in rats.
European journal of pharmacology 1998;355(2-3):113-8.
-
1998: Cook S A; Lowe J A; Martin B R
CB1 receptor antagonist precipitates withdrawal in mice exposed to Delta9-tetrahydrocannabinol.
The Journal of pharmacology and experimental therapeutics 1998;285(3):1150-6.
-
1998: Wiley J L; Compton D R; Dai D; Lainton J A; Phillips M; Huffman J W; Martin B R
Structure-activity relationships of indole- and pyrrole-derived cannabinoids.
The Journal of pharmacology and experimental therapeutics 1998;285(3):995-1004.
-
1998: Griffin G; Atkinson P J; Showalter V M; Martin B R; Abood M E
Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes.
The Journal of pharmacology and experimental therapeutics 1998;285(2):553-60.
-
1998: Adams I B; Compton D R; Martin B R
Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain.
The Journal of pharmacology and experimental therapeutics 1998;284(3):1209-17.
-
1998: Damaj M I; Fei-Yin M; Dukat M; Glassco W; Glennon R A; Martin B R
Antinociceptive responses to nicotinic acetylcholine receptor ligands after systemic and intrathecal administration in mice.
The Journal of pharmacology and experimental therapeutics 1998;284(3):1058-65.
-
1997: Wiley J L; Golden K M; Ryan W J; Balster R L; Razdan R K; Martin B R
Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys.
Pharmacology, biochemistry, and behavior 1997;58(4):1139-43.
-
1997: Compton D R; Martin B R
The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity.
The Journal of pharmacology and experimental therapeutics 1997;283(3):1138-43.
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1997: Wagner J A; Varga K; Ellis E F; Rzigalinski B A; Martin B R; Kunos G
Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock.
Nature 1997;390(6659):518-21.
-
1997: Seltzman H H; Fleming D N; Thomas B F; Gilliam A F; McCallion D S; Pertwee R G; Compton D R; Martin B R
Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide.
Journal of medicinal chemistry 1997;40(22):3626-34.
-
1997: Reggio P H; Wang T; Brown A E; Fleming D N; Seltzman H H; Griffin G; Pertwee R G; Compton D R; Abood M E; Martin B R
Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs.
Journal of medicinal chemistry 1997;40(20):3312-8.
-
1997: Damaj M I; Glassco W; Marks M J; Slobe B; James J R; May E L; Rosecrans J A; Collins A C; Martin B R
Pharmacological investigation of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H-pyrrolo-[3,2-h]isoq uinoline, a bridged-nicotine analog.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1425-34.
-
1997: Dutta A K; Ryan W; Thomas B F; Singer M; Compton D R; Martin B R; Razdan R K
Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs).
Bioorganic & medicinal chemistry 1997;5(8):1591-600.
-
1997: Damaj M I; Patrick G S; Creasy K R; Martin B R
Pharmacology of lobeline, a nicotinic receptor ligand.
The Journal of pharmacology and experimental therapeutics 1997;282(1):410-9.
-
1997: Willoughby K A; Moore S F; Martin B R; Ellis E F
The biodisposition and metabolism of anandamide in mice.
The Journal of pharmacology and experimental therapeutics 1997;282(1):243-7.
-
1997: Lake K D; Compton D R; Varga K; Martin B R; Kunos G
Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.
The Journal of pharmacology and experimental therapeutics 1997;281(3):1030-7.
-
1997: Lichtman A H; Martin B R
The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats.
Pharmacology, biochemistry, and behavior 1997;57(1-2):7-12.
-
1997: Lake K D; Martin B R; Kunos G; Varga K
Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats.
Hypertension 1997;29(5):1204-10.
-
1997: Meng Y; Lichtman A H; Bridgen D T; Martin B R
Inhalation studies with drugs of abuse.
NIDA research monograph 1997;173():201-24.
-
1996: Meng Y; Lichtman A H; Bridgen D T; Martin B R
Pharmacological potency and biodisposition of phencyclidine via inhalation exposure in mice.
Drug and alcohol dependence 1996;43(1-2):13-22.
-
1996: Adams I B; Martin B R
Cannabis: pharmacology and toxicology in animals and humans.
Addiction (Abingdon, England) 1996;91(11):1585-614.
-
1996: Pertwee R G; Fernando S R; Griffin G; Ryan W; Razdan R K; Compton D R; Martin B R
Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations.
European journal of pharmacology 1996;315(2):195-201.
-
1996: Lichtman A H; Meng Y; Martin B R
Inhalation exposure to volatilized opioids produces antinociception in mice.
The Journal of pharmacology and experimental therapeutics 1996;279(1):69-76.
-
1996: Huffman J W; Yu S; Showalter V; Abood M E; Wiley J L; Compton D R; Martin B R; Bramblett R D; Reggio P H
Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.
Journal of medicinal chemistry 1996;39(20):3875-7.
-
1996: Aceto M D; Scates S M; Lowe J A; Martin B R
Dependence on delta 9-tetrahydrocannabinol: studies on precipitated and abrupt withdrawal.
The Journal of pharmacology and experimental therapeutics 1996;278(3):1290-5.
-
1996: Showalter V M; Compton D R; Martin B R; Abood M E
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.
The Journal of pharmacology and experimental therapeutics 1996;278(3):989-99.
-
1996: Lichtman A H; Martin B R
Delta 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism.
Psychopharmacology 1996;126(2):125-31.
-
1996: Compton D R; Aceto M D; Lowe J; Martin B R
In vivo characterization of a specific cannabinoid receptor antagonist (SR141716A): inhibition of delta 9-tetrahydrocannabinol-induced responses and apparent agonist activity.
The Journal of pharmacology and experimental therapeutics 1996;277(2):586-94.
-
1996: Damaj M I; Martin B R
Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice.
European journal of pharmacology 1996;300(1-2):51-7.
-
1996: Damaj M I; Welch S P; Martin B R
Characterization and modulation of acute tolerance to nicotine in mice.
The Journal of pharmacology and experimental therapeutics 1996;277(1):454-61.
-
1996: Shivachar A C; Martin B R; Ellis E F
Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride].
Biochemical pharmacology 1996;51(5):669-76.
-
1996: Lichtman A H; Cook S A; Martin B R
Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement.
The Journal of pharmacology and experimental therapeutics 1996;276(2):585-93.
-
1996: Fan F; Tao Q; Abood M; Martin B R
Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice.
Brain research 1996;706(1):13-20.
-
1996: Thomas B F; Adams I B; Mascarella S W; Martin B R; Razdan R K
Structure-activity analysis of anandamide analogs: relationship to a cannabinoid pharmacophore.
Journal of medicinal chemistry 1996;39(2):471-9.
-
1996: Wiley J L; Compton D R; Gordon P M; Siegel C; Singer M; Dutta A; Lichtman A H; Balster R L; Razdan R K; Martin B R
Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol.
Neuropharmacology 1996;35(12):1793-804.
-
1996: Abood M E; Martin B R
Molecular neurobiology of the cannabinoid receptor.
International review of neurobiology 1996;39():197-221.
-
1995: Wiley J L; Huffman J W; Balster R L; Martin B R
Pharmacological specificity of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rhesus monkeys.
Drug and alcohol dependence 1995;40(1):81-6.
-
1995: Wiley J L; Lowe J A; Balster R L; Martin B R
Antagonism of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rats and rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1995;275(1):1-6.
-
1995: Damaj M I; Creasy K R; Welch S P; Rosecrans J A; Aceto M D; Martin B R
Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist.
Psychopharmacology 1995;120(4):483-90.
-
1995: Aceto M D; Scates S M; Lowe J A; Martin B R
Cannabinoid precipitated withdrawal by the selective cannabinoid receptor antagonist, SR 141716A.
European journal of pharmacology 1995;282(1-3):R1-2.
-
1995: Adams I B; Ryan W; Singer M; Thomas B F; Compton D R; Razdan R K; Martin B R
Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1172-81.
-
1995: Lichtman A H; Dimen K R; Martin B R
Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats.
Psychopharmacology 1995;119(3):282-90.
-
1995: Mechoulam R; Ben-Shabat S; Hanus L; Ligumsky M; Kaminski N E; Schatz A R; Gopher A; Almog S; Martin B R; Compton D R
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors.
Biochemical pharmacology 1995;50(1):83-90.
-
1995: Wiley J L; Barrett R L; Lowe J; Balster R L; Martin B R
Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats.
Neuropharmacology 1995;34(6):669-76.
-
1995: Lichtman A H; Sathe P; Dimen K R; Martin B R
Acute tolerance to the cardiovascular effects of volatilized cocaine free base in rats.
Drug and alcohol dependence 1995;38(3):247-54.
-
1995: Varga K; Lake K; Martin B R; Kunos G
Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide.
European journal of pharmacology 1995;278(3):279-83.
-
1995: Woodward J J; Compton D M; Balster R L; Martin B R
In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter.
European journal of pharmacology 1995;277(1):7-13.
-
1995: Glennon R A; Young R; Martin B R; Dal Cason T A
Methcathione ("cat"): an enantiomeric potency comparison.
Pharmacology, biochemistry, and behavior 1995;50(4):601-6.
-
1995: Barrett R L; Wiley J L; Balster R L; Martin B R
Pharmacological specificity of delta 9-tetrahydrocannabinol discrimination in rats.
Psychopharmacology 1995;118(4):419-24.
-
1995: Martin B R; Compton D R; Prescott W R; Barrett R L; Razdan R K
Pharmacological evaluation of dimethylheptyl analogs of delta 9-THC: reassessment of the putative three-point cannabinoid-receptor interaction.
Drug and alcohol dependence 1995;37(3):231-40.
-
1995: Damaj M I; Welch S P; Martin B R
In vivo pharmacological effects of dihydro-beta-erythroidine, a nicotinic antagonist, in mice.
Psychopharmacology 1995;117(1):67-73.
-
1995: Cook S A; Welch S P; Lichtman A H; Martin B R
Evaluation of cAMP involvement in cannabinoid-induced antinociception.
Life sciences 1995;56(23-24):2049-56.
-
1995: Adams I B; Ryan W; Singer M; Razdan R K; Compton D R; Martin B R
Pharmacological and behavioral evaluation of alkylated anandamide analogs.
Life sciences 1995;56(23-24):2041-8.
-
1995: Ryan W; Singer M; Razdan R K; Compton D R; Martin B R
A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS.
Life sciences 1995;56(23-24):2013-20.
-
1994: Fan F; Compton D R; Ward S; Melvin L; Martin B R
Development of cross-tolerance between delta 9-tetrahydrocannabinol, CP 55,940 and WIN 55,212.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1383-90.
-
1994: Damaj M I; Creasy K R; Grove A D; Rosecrans J A; Martin B R
Pharmacological effects of epibatidine optical enantiomers.
Brain research 1994;664(1-2):34-40.
-
1994: Mechoulam R; Hanus L; Martin B R
Search for endogenous ligands of the cannabinoid receptor.
Biochemical pharmacology 1994;48(8):1537-44.
-
1994: May E L; Aceto M D; Bowman E R; Bentley C; Martin B R; Harris L S; Medzihradsky F; Mattson M V; Jacobson A E
Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties.
Journal of medicinal chemistry 1994;37(20):3408-18.
-
1994: Yan G; Yin D; Khanolkar A D; Compton D R; Martin B R; Makriyannis A
Synthesis and pharmacological properties of 11-hydroxy-3-(1',1'-dimethylheptyl)hexahydrocannabinol: a high-affinity cannabinoid agonist.
Journal of medicinal chemistry 1994;37(16):2619-22.
-
1994: McLaughlin C R; Martin B R; Compton D R; Abood M E
Cannabinoid receptors in developing rats: detection of mRNA and receptor binding.
Drug and alcohol dependence 1994;36(1):27-31.
-
1994: Smith P B; Compton D R; Welch S P; Razdan R K; Mechoulam R; Martin B R
The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice.
The Journal of pharmacology and experimental therapeutics 1994;270(1):219-27.
-
1994: Damaj M I; Welch S P; Martin B R
Nicotine-induced antinociception in mice: role of G-proteins and adenylate cyclase.
Pharmacology, biochemistry, and behavior 1994;48(1):37-42.
-
1994: Smith P B; Welch S P; Martin B R
Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.
The Journal of pharmacology and experimental therapeutics 1994;268(3):1381-7.
-
1994: Damaj M I; Glennon R A; Martin B R
Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice.
Brain research bulletin 1994;33(2):199-203.
-
1994: Martin B R; Welch S P; Abood M
Progress toward understanding the cannabinoid receptor and its second messenger systems.
Advances in pharmacology (San Diego, Calif.) 1994;25():341-97.
-
1993: Lichtman A H; Smith F L; Martin B R
Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature.
Pain 1993;55(3):283-95.
-
1993: Abood M E; Sauss C; Fan F; Tilton C L; Martin B R
Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain.
Pharmacology, biochemistry, and behavior 1993;46(3):575-9.
-
1993: Martin B R; Compton D R; Semus S F; Lin S; Marciniak G; Grzybowska J; Charalambous A; Makriyannis A
Pharmacological evaluation of iodo and nitro analogs of delta 8-THC and delta 9-THC.
Pharmacology, biochemistry, and behavior 1993;46(2):295-301.
-
1993: Glassco W; Suchocki J; George C; Martin B R; May E L
Synthesis, optical resolution, absolute configuration, and preliminary pharmacology of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H- pyrrolo-[3,2-h]isoquinoline, a structural analog of nicotine.
Journal of medicinal chemistry 1993;36(22):3381-5.
-
1993: Damaj M I; Welch S P; Martin B R
Involvement of calcium and L-type channels in nicotine-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1993;266(3):1330-8.
-
1993: Compton D R; Rice K C; De Costa B R; Razdan R K; Melvin L S; Johnson M R; Martin B R
Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.
The Journal of pharmacology and experimental therapeutics 1993;265(1):218-26.
-
1993: Wiley J L; Barrett R L; Britt D T; Balster R L; Martin B R
Discriminative stimulus effects of delta 9-tetrahydrocannabinol and delta 9-11-tetrahydrocannabinol in rats and rhesus monkeys.
Neuropharmacology 1993;32(4):359-65.
-
1993: Lu R; Hubbard J R; Martin B R; Kalimi M Y
Roles of sulfhydryl and disulfide groups in the binding of CP-55,940 to rat brain cannabinoid receptor.
Molecular and cellular biochemistry 1993;121(2):119-26.
-
1993: Damaj M I; Martin B R
Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility.
Drug and alcohol dependence 1993;32(1):73-9.
-
1993: Martin B R; Cabral G; Childers S R; Deadwyler S; Mechoulam R; Reggio P
International Cannabis Research Society meeting summary, Keystone, CO (June 19-20, 1992).
Drug and alcohol dependence 1993;31(3):219-27.
-
1993: Damaj M I; Martin B R
Is the dopaminergic system involved in the central effects of nicotine in mice?
Psychopharmacology 1993;111(1):106-8.
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1992: Thomas B F; Wei X; Martin B R
Characterization and autoradiographic localization of the cannabinoid binding site in rat brain using [3H]11-OH-delta 9-THC-DMH.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1383-90.
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1992: Compton D R; Gold L H; Ward S J; Balster R L; Martin B R
Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol.
The Journal of pharmacology and experimental therapeutics 1992;263(3):1118-26.
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1992: Kaminski N E; Abood M E; Kessler F K; Martin B R; Schatz A R
Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation.
Molecular pharmacology 1992;42(5):736-42.
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1992: Lichtman A H; Smith P B; Martin B R
The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity.
Pain 1992;51(1):19-26.
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1992: Martin B R; Prescott W R; Zhu M
Quantitation of rodent catalepsy by a computer-imaging technique.
Pharmacology, biochemistry, and behavior 1992;43(2):381-6.
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1992: Darmani N A; Martin B R; Glennon R A
Behavioral evidence for differential adaptation of the serotonergic system after acute and chronic treatment with (+/- )-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) or ketanserin.
The Journal of pharmacology and experimental therapeutics 1992;262(2):692-8.
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1992: Charalambous A; Yan G; Houston D B; Howlett A C; Compton D R; Martin B R; Makriyannis A
5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor.
Journal of medicinal chemistry 1992;35(16):3076-9.
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1992: Gold L H; Balster R L; Barrett R L; Britt D T; Martin B R
A comparison of the discriminative stimulus properties of delta 9-tetrahydrocannabinol and CP 55,940 in rats and rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1992;262(2):479-86.
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1992: Darmani N A; Schnoll S H; Pandey U; Martin B R
Chronic prenatal methadone exposure alters central opioid mu-receptor affinity in both fetal and maternal brain.
Neurotoxicology and teratology 1992;14(4):265-71.
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1992: Abood M E; Martin B R
Neurobiology of marijuana abuse.
Trends in pharmacological sciences 1992;13(5):201-6.
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1992: Johansson E K; Tucker S M; Ginn H B; Martin B R; Aceto M D
Functional and dispositional tolerance develops during continuous cocaine exposure.
European journal of drug metabolism and pharmacokinetics 1992;17(2):155-62.
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1992: Smith P B; Martin B R
Spinal mechanisms of delta 9-tetrahydrocannabinol-induced analgesia.
Brain research 1992;578(1-2):8-12.
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1992: Darmani N A; Martin B R; Glennon R A
Repeated administration of low doses of cocaine enhances the sensitivity of 5-HT2 receptor function.
Pharmacology, biochemistry, and behavior 1992;41(3):519-27.
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1992: Compton D R; Johnson M R; Melvin L S; Martin B R
Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents.
The Journal of pharmacology and experimental therapeutics 1992;260(1):201-9.
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1992: Prescott W R; Gold L H; Martin B R
Evidence for separate neuronal mechanisms for the discriminative stimulus and catalepsy induced by delta 9-THC in the rat.
Psychopharmacology 1992;107(1):117-24.
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1991: Thomas B F; Compton D R; Martin B R; Semus S F
Modeling the cannabinoid receptor: a three-dimensional quantitative structure-activity analysis.
Molecular pharmacology 1991;40(5):656-65.
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1991: Reggio P H; McGaughey G B; Odear D F; Seltzman H H; Compton D R; Martin B R
A rational search for the separation of psychoactivity and analgesia in cannabinoids.
Pharmacology, biochemistry, and behavior 1991;40(3):479-86.
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1991: Darmani N A; Saady J J; Schnoll S H; Martin B R
Demonstration of physical dependence following chronic continuous methadone delivery via osmotic minipumps in pregnant rats.
Neurotoxicology and teratology 1991;13(6):627-30.
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1991: Charalambous A; Lin S; Marciniak G; Banijamali A; Friend F L; Compton D R; Martin B R; Makriyannis A
Pharmacological evaluation of halogenated delta 8-THC analogs.
Pharmacology, biochemistry, and behavior 1991;40(3):509-12.
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1991: Martin B R; Compton D R; Thomas B F; Prescott W R; Little P J; Razdan R K; Johnson M R; Melvin L S; Mechoulam R; Ward S J
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs.
Pharmacology, biochemistry, and behavior 1991;40(3):471-8.
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1991: Compton D R; Prescott W R; Martin B R; Siegel C; Gordon P M; Razdan R K
Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol.
Journal of medicinal chemistry 1991;34(11):3310-6.
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1991: Lichtman A H; Martin B R
Cannabinoid-induced antinociception is mediated by a spinal alpha 2-noradrenergic mechanism.
Brain research 1991;559(2):309-14.
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1991: Lichtman A H; Martin B R
Spinal and supraspinal components of cannabinoid-induced antinociception.
The Journal of pharmacology and experimental therapeutics 1991;258(2):517-23.
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1991: Boni J P; Barr W H; Martin B R
Cocaine inhalation in the rat: pharmacokinetics and cardiovascular response.
The Journal of pharmacology and experimental therapeutics 1991;257(1):307-15.
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1991: Suchocki J A; May E L; Martin T J; George C; Martin B R
Synthesis of 2-exo- and 2-endo-mecamylamine analogues. Structure-activity relationships for nicotinic antagonism in the central nervous system.
Journal of medicinal chemistry 1991;34(3):1003-10.
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1991: Darmani N A; Martin B R; Pandey U; Glennon R A
Inhibition of 5-HT2 receptor-mediated head-twitch response by cocaine via indirect stimulation of adrenergic alpha 2 and serotonergic 5-HT1A receptors.
Pharmacology, biochemistry, and behavior 1991;38(2):353-7.
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1991: Darmani N A; Schnoll S H; Fuchs B; Martin B R
Does chronic prenatal methadone exposure affect beta-receptor subtypes in placental, fetal and maternal brain homogenates?
Neurotoxicology and teratology 1991;13(1):43-8.
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1991: Glennon R A; Darmani N A; Martin B R
Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents.
Life sciences 1991;48(26):2493-8.
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1991: Little P J; Martin B R
The effects of delta 9-tetrahydrocannabinol and other cannabinoids on cAMP accumulation in synaptosomes.
Life sciences 1991;48(12):1133-41.
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1990: Reggio P H; Seltzman H H; Compton D R; Prescott W R; Martin B R
Investigation of the role of the phenolic hydroxyl in cannabinoid activity.
Molecular pharmacology 1990;38(6):854-62.
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1990: Thomas B F; Compton D R; Martin B R
Characterization of the lipophilicity of natural and synthetic analogs of delta 9-tetrahydrocannabinol and its relationship to pharmacological potency.
The Journal of pharmacology and experimental therapeutics 1990;255(2):624-30.
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1990: Thomas B F; Martin B R
In vitro metabolism of (-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl) phenyl]-trans-4-(3-hydroxypropyl) cyclohexanol, a synthetic bicyclic cannabinoid analog.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):1046-54.
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1990: Darmani N A; Martin B R; Glennon R A
Withdrawal from chronic treatment with (+/-)-DOI causes super-sensitivity to 5-HT2 receptor-induced head-twitch behaviour in mice.
European journal of pharmacology 1990;186(1):115-8.
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1990: Darmani N A; Martin B R; Pandey U; Glennon R A
Pharmacological characterization of ear-scratch response in mice as a behavioral model for selective 5-HT2-receptor agonists and evidence for 5-HT1B- and 5-HT2-receptor interactions.
Pharmacology, biochemistry, and behavior 1990;37(1):95-9.
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1990: Darmani N A; Martin B R; Pandey U; Glennon R A
Do functional relationships exist between 5-HT1A and 5-HT2 receptors?
Pharmacology, biochemistry, and behavior 1990;36(4):901-6.
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1990: Martin T J; Suchocki J; May E L; Martin B R
Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine.
The Journal of pharmacology and experimental therapeutics 1990;254(1):45-51.
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1990: Onaivi E S; Green M R; Martin B R
Pharmacological characterization of cannabinoids in the elevated plus maze.
The Journal of pharmacology and experimental therapeutics 1990;253(3):1002-9.
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1990: Compton D R; Little P J; Martin B R; Gilman J W; Saha J K; Jorapur V S; Sard H P; Razdan R K
Synthesis and pharmacological evaluation of amino, azido, and nitrogen mustard analogues of 10-substituted cannabidiol and 11- or 12-substituted delta 8-tetrahydrocannabinol.
Journal of medicinal chemistry 1990;33(5):1437-43.
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1990: Gennings C; Carter W H; Campbell E D; Staniswalis J G; Martin T J; Martin B R; White K L
Isobolographic characterization of drug interactions incorporating biological variability.
The Journal of pharmacology and experimental therapeutics 1990;252(1):208-17.
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1990: Darmani N A; Hadfield M G; Carter W H; Martin B R
Acute and chronic effects of cocaine on isolation-induced aggression in mice.
Psychopharmacology 1990;102(1):37-40.
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1990: Compton D R; Martin B R
Pharmacological evaluation of water soluble cannabinoids and related analogs.
Life sciences 1990;46(22):1575-85.
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1990: Martin B R; Boni J
Pyrolysis and inhalation studies with phencyclidine and cocaine.
NIDA research monograph 1990;99():141-58.
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1990: Compton D R; Dewey W L; Martin B R
Cannabis dependence and tolerance production.
Advances in alcohol & substance abuse 1990;9(1-2):129-47.
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1990: Todd S L; Balster R L; Martin B R
Affinity of the enantiomers of alpha- and beta-cyclazocine for binding to the phencyclidine and mu opioid receptors.
Life sciences 1990;46(12):895-901.
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1990: Lichtman A H; Martin B R
Spinal action of cannabinoid-induced antinociception.
NIDA research monograph 1990;105():422-4.
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1990: Prescott W R; Martin B R
The evaluation of synthetic cannabimimetic congeners for discriminative stimulus and cataleptogenic effects in rats.
NIDA research monograph 1990;105():421.
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1990: Compton D R; Prescott W R; Siegel C S; Gordon P M; Razdan R K; Martin B R
Evaluation of ether and free hydroxyl analogs of delta-8, delta-9, 11-THC as cannabinoid antagonists.
NIDA research monograph 1990;105():297-8.
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1989: Onaivi E S; Todd S; Martin B R
Behavioral effects in the mouse during and following withdrawal from ethanol ingestion and/or nicotine administration.
Drug and alcohol dependence 1989;24(3):205-11.
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1989: Martin B R; Onaivi E S; Martin T J
What is the nature of mecamylamine's antagonism of the central effects of nicotine?
Biochemical pharmacology 1989;38(20):3391-7.
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1989: Martin B R; Lue L P; Boni J P
Pyrolysis and volatilization of cocaine.
Journal of analytical toxicology 1989;13(3):158-62.
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1989: Little P J; Compton D R; Mechoulam R; Martin B R
Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs.
Pharmacology, biochemistry, and behavior 1989;32(3):661-6.
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1989: Suchocki J A; Martin T J; May E L; Martin B R
Synthesis of exo and endo mecamylamine analogs for nicotinic antagonism in the CNS.
NIDA research monograph 1989;95():546-7.
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1989: Martin T J; Suchocki J; May E L; Martin B R
Structural requirements for nicotinic antagonists in the CNS.
NIDA research monograph 1989;95():514-5.
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1989: Thomas B F; Martin B R
Identification of metabolites of CP-55,940 formed in-vitro by mouse livers.
NIDA research monograph 1989;95():287-8.
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1989: Onaivi E S; Martin B R
Neuropharmacological and physiological validation of a computer-controlled two-compartment black and white box for the assessment of anxiety.
Progress in neuro-psychopharmacology & biological psychiatry 1989;13(6):963-76.
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1989: Little P J; Martin B R
Cannabinoid modulation of cyclic AMP accumulation in synaptosomes.
NIDA research monograph 1989;95():282-3.
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1988: Little P J; Compton D R; Johnson M R; Melvin L S; Martin B R
Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.
The Journal of pharmacology and experimental therapeutics 1988;247(3):1046-51.
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1988: Scimeca J A; Martin B R
The effect of acute dyflos (DFP) treatment on [3H]nicotine binding to mouse brain homogenate.
The Journal of pharmacy and pharmacology 1988;40(11):793-7.
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1988: Scimeca J A; Martin B R
The disposition of [3H]diisopropylfluorophosphate in guinea pigs after inhalation.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(4):534-9.
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1988: Little P J; Scimeca J A; Martin B R
Distribution of [3H]diisopropylfluorophosphate, [3H]soman, [3H]sarin, and their metabolites in mouse brain.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(4):515-20.
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1988: Lyddane J E; Thomas B F; Compton D R; Martin B R
Modification of phencyclidine intoxification and biodisposition by charcoal and other treatments.
Pharmacology, biochemistry, and behavior 1988;30(2):371-7.
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1988: Lue L P; Scimeca J A; Thomas B F; Martin B R
Pyrolytic fate of piperidinocyclohexanecarbonitrile, a contaminant of phencyclidine, during smoking.
Journal of analytical toxicology 1988;12(2):57-61.
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1987: Martin B R; Compton D R; Little P J; Martin T J; Beardsley P M
Pharmacological evaluation of agonistic and antagonistic activity of cannabinoids.
NIDA research monograph 1987;79():108-22.
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1986: Lue L P; Scimeca J A; Thomas B F; Martin B R
Identification and quantification of phencyclidine pyrolysis products formed during smoking.
Journal of analytical toxicology 1986;10(3):81-6.
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1981: Freeman A S; Martin B R
Quantification of phencyclidine in mainstream smoke and identification of phenylcyclohex-1-ene as pyrolysis product.
Journal of pharmaceutical sciences 1981;70(9):1002-4.
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1980: Vincek W C; Martin B R; Aceto M D; Bowman E R
Synthesis and preliminary binding studies of 4,4-ditritio-(-)-nicotine of high specific activity.
Journal of medicinal chemistry 1980;23(8):960-2.
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