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Flavius Martin

Research Profile

Living Beings

Anatomy

Physiology

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Genes, Immunoglobulin

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Publications

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David F Choy; Maxwell A Fung; Daniel K Hsu; Fu-Tong Liu; Flavius Martin; Zora Modrusan; Dhaya Seshasayee; Joseph R Arron
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.
Anwesha Dey; Omar Abdel-Wahab; Corey E Bakalarski; Margit Balazs; Mira S Chaurushiya; Ken Dong; Dorothy M French; Guillermo Garcia-Manero; Sarah G Hymowitz; Paula Katavolos; Donald S Kirkpatrick; Lindsay M LaFave; Ross L Levine; Jennie R Lill; Zhonghua Lin; Jinfeng Liu; Flavius Martin; Zora Modrusan; Kim Newton; Rajkumar Noubade; Victoria C Pham; Lilian Phu; Somasekar Seshagiri; Dhaya Seshasayee; Rowena Suriben; Jiansheng Wu; Vishva M Dixit
Loss of the tumor suppressor BAP1 causes myeloid transformation.
Flavius Martin; Vishva M Dixit
A20 edits ubiquitin and autoimmune paradigms.

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All Publications

2012: David F Choy; Maxwell A Fung; Daniel K Hsu; Fu-Tong Liu; Flavius Martin; Zora Modrusan; Dhaya Seshasayee; Joseph R Arron
Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.
The Journal of allergy and clinical immunology 2012;130(6):1335-43.e5.
2012: Anwesha Dey; Omar Abdel-Wahab; Corey E Bakalarski; Margit Balazs; Mira S Chaurushiya; Ken Dong; Dorothy M French; Guillermo Garcia-Manero; Sarah G Hymowitz; Paula Katavolos; Donald S Kirkpatrick; Lindsay M LaFave; Ross L Levine; Jennie R Lill; Zhonghua Lin; Jinfeng Liu; Flavius Martin; Zora Modrusan; Kim Newton; Rajkumar Noubade; Victoria C Pham; Lilian Phu; Somasekar Seshagiri; Dhaya Seshasayee; Rowena Suriben; Jiansheng Wu; Vishva M Dixit
Loss of the tumor suppressor BAP1 causes myeloid transformation.
Science (New York, N.Y.) 2012;337(6101):1541-6.
2011: Flavius Martin; Vishva M Dixit
A20 edits ubiquitin and autoimmune paradigms.
Nature genetics 2011;43(9):822-3.
2010: Amin Al-Shami; Carrie Wilkins; Jeannette Crisostomo; Dhaya Seshasayee; Flavius Martin; Nianhua Xu; Adisak Suwanichkul; Stephen J Anderson; Tamas Oravecz
The adaptor protein Sh2d3c is critical for marginal zone B cell development and function.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(1):327-34.
2008: Flavius Martin
Transplantation: it may take two to tango and to treat.
Immunology and cell biology 2008;86(2):107-8.
2007: Dhaya Seshasayee; Wyne P Lee; Meijuan Zhou; Jean Shu; Eric Suto; Juan Zhang; Lauri Diehl; Cary D Austin; Y Gloria Meng; Martha Tan; Sherron Bullens; Stefan Seeber; Maria E Fuentes; Aran F Labrijn; Yvo M F Graus; Lisa A Miller; Edward S Schelegle; Dallas M Hyde; Lawren C Wu; Sarah G Hymowitz; Flavius Martin
In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
The Journal of clinical investigation 2007;117(12):3868-78.
2007: Wei Yu Lin; Qian Gong; Dhaya Seshasayee; Zhonghua Lin; Qinglin Ou; Shiming Ye; Eric Suto; Jean Shu; Wyne P Lee; Ching-Wei V Lee; Germaine Fuh; Maya Leabman; Suhasini Iyer; Kathy Howell; Thomas Gelzleichter; Joseph Beyer; Dimitry M Danilenko; Sherry Yeh; Laura E DeForge; Allen Ebens; Jeffrey S Thompson; Christine Ambrose; Margit Balazs; Melissa A Starovasnik; Flavius Martin
Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.
Blood 2007;110(12):3959-67.
2006: Chingwei V Lee; Sarah G Hymowitz; Heidi J A Wallweber; Nathaniel C Gordon; Karen L Billeci; Siao Ping Tsai; Deanne M Compaan; Jianping Yin; Qian Gong; Robert F Kelley; Laura E DeForge; Flavius Martin; Melissa A Starovasnik; Germaine Fuh
Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood 2006;108(9):3103-11.
2006: Yulia Vugmeyster; Dhaya Seshasayee; Wesley Chang; Anahid Storn; Kathy Howell; Susan Sa; Tenea Nelson; Flavius Martin; Iqbal Grewal; Ellen Gilkerson; Ben Wu; Jeff Thompson; Barbara N Ehrenfels; Song Ren; An Song; Thomas Gelzleichter; Dimitry M Danilenko
A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys.
The American journal of pathology 2006;168(2):476-89.
2006: Flavius Martin; Andrew C Chan
B cell immunobiology in disease: evolving concepts from the clinic.
Annual review of immunology 2006;24():467-96.
2005: Flavius Martin; Xiaodong Huang
Unraveling TACIt functions.
Nature genetics 2005;37(8):793-4.
2005: Qian Gong; Qinglin Ou; Shiming Ye; Wyne P Lee; Jennine Cornelius; Lauri Diehl; Wei Yu Lin; Zhilan Hu; Yanmei Lu; Yongmei Chen; Yan Wu; Y Gloria Meng; Peter Gribling; Zhonghua Lin; Kathy Nguyen; Thanhvien Tran; Yifan Zhang; Hugh Rosen; Flavius Martin; Andrew C Chan
Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):817-26.
2004: Weimin Liu; Alexander Szalai; Limin Zhao; Di Liu; Flavius Martin; Robert P Kimberly; Tong Zhou; Robert H Carter
Control of spontaneous B lymphocyte autoimmunity with adenovirus-encoded soluble TACI.
Arthritis and rheumatism 2004;50(6):1884-96.
2004: Flavius Martin; Andrew C Chan
Pathogenic roles of B cells in human autoimmunity; insights from the clinic.
Immunity 2004;20(5):517-27.
2004: Eugene Varfolomeev; Frank Kischkel; Flavius Martin; Dhaya Seshasayee; Hua Wang; David Lawrence; Christine Olsson; Lucrece Tom; Sharon Erickson; Dorothy French; Peter Schow; Iqbal Grewal; Avi Ashkenazi
APRIL-deficient mice have normal immune system development.
Molecular and cellular biology 2004;24(3):997-1006.
2004: Kiminori Hasegawa; Flavius Martin; Guangming Huang; Dan Tumas; Lauri Diehl; Andrew C Chan
PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells.
Science (New York, N.Y.) 2004;303(5658):685-9.
2002: Margit Balázs; Flavius Martin; Tong Zhou; John Kearney
Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses.
Immunity 2002;17(3):341-52.
2002: Flavius Martin; John F Kearney
Marginal-zone B cells.
Nature reviews. Immunology 2002;2(5):323-35.
2001: Flavius Martin; Alyce M. Oliver; John F Kearney
Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens.
Immunity 2001;14(5):617-29.
2001: Flavius Martin; John F Kearney
B1 cells: similarities and differences with other B cell subsets.
Current opinion in immunology 2001;13(2):195-201.
2001: Xiaoli Li; Flavius Martin; Alyce M. Oliver; John F Kearney; Robert H Carter
Antigen receptor proximal signaling in splenic B-2 cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3122-9.
2000: Flavius Martin; John F Kearney
B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".
Immunological reviews 2000;175():70-9.
2000: Flavius Martin; John F Kearney
Selection in the mature B cell repertoire.
Current topics in microbiology and immunology 2000;252():97-105.
2000: Flavius Martin; John F Kearney
Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk.
Immunity 2000;12(1):39-49.
1999: Alyce M. Oliver; Flavius Martin; John F Kearney
IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(12):7198-207.
1999: Flavius Martin; John F Kearney
CD21high IgMhigh splenic B cells enriched in the marginal zone: distinct phenotypes and functions.
Current topics in microbiology and immunology 1999;246():45-50; discussion 51-2.
1998: Flavius Martin; Woong-Jai Won; John F Kearney
Generation of the germline peripheral B cell repertoire: VH81X-lambda B cells are unable to complete all developmental programs.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3748-58.
1997: Alyce M. Oliver; Flavius Martin; G Larry Gartland; Robert H Carter; John F Kearney
Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses.
European journal of immunology 1997;27(9):2366-74.
1997: Flavius Martin; X Chen; John F Kearney
Development of VH81X transgene-bearing B cells in fetus and adult: sites for expansion and deletion in conventional and CD5/B1 cells.
International immunology 1997;9(4):493-505.
1997: Alyce M. Oliver; Flavius Martin; John F Kearney
Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1108-15.
1997: John F Kearney; Woong-Jai Won; C Benedict; C Moratz; P Zimmer; Alyce M. Oliver; Flavius Martin; Fengyu Shu
B cell development in mice.
International reviews of immunology 1997;15(3-4):207-41.
1997: X Chen; Flavius Martin; Katherine Forbush; Roger M Perlmutter; John F Kearney
Evidence for selection of a population of multi-reactive B cells into the splenic marginal zone.
International immunology 1997;9(1):27-41.
1995: Flavius Martin; X Chen; F Shu; John F Kearney
Development of the mouse B-cell repertoire.
Annals of the New York Academy of Sciences 1995;764():207-21.