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Régis Bataille

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Sylvanie Surget; Martine Amiot; Régis Bataille; David CHIRON; Géraldine Descamps; Patricia Gomez-Bougie; Steven Le Gouill; Emmanuelle Ménoret; Philippe Moreau; Catherine Pellat-Deceunynck
Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells.
David CHIRON; Géraldine Descamps; Bernard Klein; Steven Le Gouill; Sophie Maïga; Séverine Marionneau; Philippe Moreau; Jérôme Moreaux; Thibauld Ouiller; Martine Amiot; Régis Bataille; Catherine Pellat-Deceunynck
Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells.
David CHIRON; Steven Le Gouill; Sophie Maïga; Philippe Moreau; Martine Amiot; Régis Bataille; Sylvanie Surget; Catherine Pellat-Deceunynck
The peripheral CD138+ population but not the CD138- population contains myeloma clonogenic cells in plasma cell leukaemia patients.

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2012: Sylvanie Surget; Martine Amiot; Régis Bataille; David CHIRON; Géraldine Descamps; Patricia Gomez-Bougie; Steven Le Gouill; Emmanuelle Ménoret; Philippe Moreau; Catherine Pellat-Deceunynck
Cell death via DR5, but not DR4, is regulated by p53 in myeloma cells.
Cancer research 2012;72(17):4562-73.
2012: David CHIRON; Géraldine Descamps; Bernard Klein; Steven Le Gouill; Sophie Maïga; Séverine Marionneau; Philippe Moreau; Jérôme Moreaux; Thibauld Ouiller; Martine Amiot; Régis Bataille; Catherine Pellat-Deceunynck
Critical role of the NOTCH ligand JAG2 in self-renewal of myeloma cells.
Blood cells, molecules & diseases 2012;48(4):247-53.
2012: David CHIRON; Steven Le Gouill; Sophie Maïga; Philippe Moreau; Martine Amiot; Régis Bataille; Sylvanie Surget; Catherine Pellat-Deceunynck
The peripheral CD138+ population but not the CD138- population contains myeloma clonogenic cells in plasma cell leukaemia patients.
British journal of haematology 2012;156(5):679-83.
2011: Linda Bodet; Géraldine Descamps; Christelle Dousset; Patricia Gomez-Bougie; Steven Le Gouill; Sophie Maïga; Philippe Moreau; Catherine Pellat-Deceunynck; Cyrille Touzeau; Hervé Avet-Loiseau; Régis Bataille; Martine Amiot
ABT-737 is highly effective against molecular subgroups of multiple myeloma.
Blood 2011;118(14):3901-10.
2010: L Bodet; E Ménoret; Géraldine Descamps; Catherine Pellat-Deceunynck; Régis Bataille; Steven Le Gouill; Philippe Moreau; Martine Amiot; Patricia Gomez-Bougie
BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma.
British journal of cancer 2010;103(12):1808-14.
2009: David CHIRON; Catherine Pellat-Deceunynck; Mike Maillasson; Régis Bataille; G Jego
Phosphorothioate-modified TLR9 ligands protect cancer cells against TRAIL-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4371-7.
2009: Pascal Jézéquel; Mario Campone; Henri Roché; Wilfried Gouraud; Catherine Charbonnel; Gabriel Ricolleau; Florence Magrangeas; Stéphane Minvielle; Jean Genève; Anne-Laure Martin; Régis Bataille; Loïc Campion
A 38-gene expression signature to predict metastasis risk in node-positive breast cancer after systemic adjuvant chemotherapy: a genomic substudy of PACS01 clinical trial.
Breast cancer research and treatment 2009;116(3):509-20.
2009: David CHIRON; Catherine Pellat-Deceunynck; Martine Amiot; Régis Bataille; G Jego
TLR3 ligand induces NF-{kappa}B activation and various fates of multiple myeloma cells depending on IFN-{alpha} production.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4471-8.
2009: Mathilde Romagnoli; Céline Séveno; Soraya Wuillème-Toumi; Martine Amiot; Régis Bataille; Stéphane Minvielle; Sophie Barillé-Nion
The imbalance between Survivin and Bim mediates tumour growth and correlates with poor survival in patients with multiple myeloma.
British journal of haematology 2009;145(2):180-9.
2009: Géraldine Descamps; P Gomez-Bougie; Corinne Venot; Philippe Moreau; Régis Bataille; Martine Amiot
A humanised anti-IGF-1R monoclonal antibody (AVE1642) enhances Bortezomib-induced apoptosis in myeloma cells lacking CD45.
British journal of cancer 2009;100(2):366-9.
2009: Grégoire Desplanques; Nicola Giuliani; Roberto Delsignore; Vittorio Rizzoli; Régis Bataille; Sophie Barillé-Nion
Impact of XIAP protein levels on the survival of myeloma cells.
Haematologica 2009;94(1):87-93.
2008: Emmanuelle Ménoret; Sophie Maïga; Géraldine Descamps; Catherine Pellat-Deceunynck; Caroline Fraslon; Melania Cappellano; Philippe Moreau; Régis Bataille; Martine Amiot
IL-21 stimulates human myeloma cell growth through an autocrine IGF-1 loop.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6837-42.
2008: Olivier Decaux; Laurence Lodé; Florence Magrangeas; Catherine Charbonnel; Wilfried Gouraud; Pascal Jézéquel; Michel Attal; Jean-Luc Harousseau; Philippe Moreau; Régis Bataille; Loïc Campion; Hervé Avet-Loiseau; Stéphane Minvielle
Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: a study of the Intergroupe Francophone du Myélome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(29):4798-805.
2008: Mathilde Romagnoli; Céline Séveno; Régis Bataille; Sophie Barillé-Nion
[Survivin in cancerology : molecular aspects and therapeutic applications].
Médecine sciences : M/S 2008;24(10):821-7.
2008: Alexandrine Geffroy-Luseau; Gaëtan Jégo; Régis Bataille; Loïc Campion; Catherine Pellat-Deceunynck
Osteoclasts support the survival of human plasma cells in vitro.
International immunology 2008;20(6):775-82.
2008: Mario Campone; Loïc Campion; Henry Roché; Wilfried Gouraud; Catherine Charbonnel; Florence Magrangeas; Stéphane Minvielle; Jean Genève; Anne-Laure Martin; Régis Bataille; Pascal Jézéquel
Prediction of metastatic relapse in node-positive breast cancer: establishment of a clinicogenomic model after FEC100 adjuvant regimen.
Breast cancer research and treatment 2008;109(3):491-501.
2007: Mathilde Romagnoli; Grégoire Desplanques; Sophie Maïga; Steven Legouill; Michel Dreano; Régis Bataille; Sophie Barillé-Nion
Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6010-8.
2007: Soraya Wuillème-Toumi; Valérie Trichet; Patricia Gomez-Bougie; Catherine Gratas; Régis Bataille; Martine Amiot
Reciprocal protection of Mcl-1 and Bim from ubiquitin-proteasome degradation.
Biochemical and biophysical research communications 2007;361(4):865-9.
2007: Madeleine Collette; Géraldine Descamps; Catherine Pellat-Deceunynck; Régis Bataille; Martine Amiot
Crucial role of phosphatase CD45 in determining signaling and proliferation of human myeloma cells.
European cytokine network 2007;18(3):120-6.
2007: Patricia Gomez-Bougie; Soraya Wuillème-Toumi; Emmanuelle Ménoret; Valérie Trichet; Nelly Robillard; Moreau Philippe; Régis Bataille; Martine Amiot
Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
Cancer research 2007;67(11):5418-24.
2007: M Romagnoli; V Trichet; C David; M Clément; P Moreau; Régis Bataille; Sophie Barillé-Nion
Significant impact of survivin on myeloma cell growth.
Leukemia 2007;21(5):1070-8.
2007: Cyrille Touzeau; Catherine Pellat-Deceunynck; Thomas Gastinne; F Accard; G Jego; Hervé Avet-Loiseau; Nelly Robillard; Jean-Luc Harousseau; Régis Bataille; Philippe Moreau
Reactive plasmacytoses can mimick plasma cell leukemia: therapeutical implications.
Leukemia & lymphoma 2007;48(1):207-8.
2006: Géraldine Descamps; Soraya Wuillème-Toumi; Valérie Trichet; Corinne Venot; Laurent Debussche; Thierry Hercend; Madeleine Collette; Nelly Robillard; Régis Bataille; Martine Amiot
CD45neg but not CD45pos human myeloma cells are sensitive to the inhibition of IGF-1 signaling by a murine anti-IGF-1R monoclonal antibody, mAVE1642.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):4218-23.
2006: Régis Bataille; Gaëtan Jégo; Nelly Robillard; Sophie Barillé-Nion; Jean-Luc Harousseau; Philippe Moreau; Martine Amiot; Catherine Pellat-Deceunynck
The phenotype of normal, reactive and malignant plasma cells. Identification of "many and multiple myelomas" and of new targets for myeloma therapy.
Haematologica 2006;91(9):1234-40.
2006: Emmanuelle Menoret; Patricia Gomez-Bougie; Alexandrine Geffroy-Luseau; Sylvanne Daniels; Philippe Moreau; Steven Le Gouill; Jean-Luc Harousseau; Régis Bataille; Martine Amiot; Catherine Pellat-Deceunynck
Mcl-1L cleavage is involved in TRAIL-R1- and TRAIL-R2-mediated apoptosis induced by HGS-ETR1 and HGS-ETR2 human mAbs in myeloma cells.
Blood 2006;108(4):1346-52.
2006: Laurent Garderet; Christelle Mazurier; Catherine Pellat-Deceunynck; Abdul Karim; Bruno Baudin; Christian Funck-Brentano; Sandrine Bouchet; Alexandrine Geffroy; Régis Bataille; Norbert-Claude Gorin; Manuel Lopez
Poor ex vivo induction of T-cell responses to idiotype or tumor cell lysate-pulsed autologous dendritic cells in advanced pre-treated multiple myeloma.
Leukemia & lymphoma 2006;47(7):1340-7.
2006: G Jego; Régis Bataille; Alexandrine Geffroy-Luseau; Géraldine Descamps; Catherine Pellat-Deceunynck
Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors.
Leukemia 2006;20(6):1130-7.
2006: Philippe Moreau; Nelly Robillard; Gaétan Jégo; Catherine Pellat; Steven Le Gouill; Soraya Thoumi; Hervé Avet-Loiseau; Jean-Luc Harousseau; Régis Bataille
Lack of CD27 in myeloma delineates different presentation and outcome.
British journal of haematology 2006;132(2):168-70.
2005: Patricia Gomez-Bougie; Lisa Oliver; Steven Le Gouill; Régis Bataille; Martine Amiot
Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex.
Oncogene 2005;24(54):8076-9.
2005: Alexandrine Geffroy-Luseau; Agnès Moreau-Aubry; Régis Bataille; Catherine Pellat-Deceunynck
Allogeneic T lymphocytes as a source of peptide-dependent T cells specific for myeloma cells.
International immunology 2005;17(9):1193-200.
2005: Soraya Wuillème-Toumi; Nelly Robillard; P Gomez; Philippe Moreau; Steven Le Gouill; Hervé Avet-Loiseau; Jean-Luc Harousseau; Martine Amiot; Régis Bataille
Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival.
Leukemia 2005;19(7):1248-52.
2005: Nelly Robillard; Catherine Pellat-Deceunynck; Régis Bataille
Phenotypic characterization of the human myeloma cell growth fraction.
Blood 2005;105(12):4845-8.
2005: Patricia Gomez-Bougie; Régis Bataille; Martine Amiot
Endogenous association of Bim BH3-only protein with Mcl-1, Bcl-xL and Bcl-2 on mitochondria in human B cells.
European journal of immunology 2005;35(3):971-6.
2004: Patricia Gomez-Bougie; Régis Bataille; Martine Amiot
The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells.
European journal of immunology 2004;34(11):3156-64.
2004: Géraldine Descamps; Catherine Pellat-Deceunynck; Yann Szpak; Régis Bataille; Nelly Robillard; Martine Amiot
The magnitude of Akt/phosphatidylinositol 3'-kinase proliferating signaling is related to CD45 expression in human myeloma cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):4953-9.
2004: Florence Magrangeas; Marie-Laure Cormier; Géraldine Descamps; Nadège Gouy; Laurence Lodé; Marie-Paule Mellerin; Jean-Luc Harousseau; Régis Bataille; Stéphane Minvielle; Hervé Avet-Loiseau
Light-chain only multiple myeloma is due to the absence of functional (productive) rearrangement of the IgH gene at the DNA level.
Blood 2004;103(10):3869-75.
2004: Philippe Moreau; Nelly Robillard; Hervé Avet-Loiseau; Danielle Pineau; Nadine Morineau; Noël Milpied; Jean-Luc Harousseau; Régis Bataille
Patients with CD45 negative multiple myeloma receiving high-dose therapy have a shorter survival than those with CD45 positive multiple myeloma.
Haematologica 2004;89(5):547-51.
2004: Nicola Giuliani; Simona Colla; Vittorio Rizzoli; Sophie Barillé-Nion; Régis Bataille
Do human myeloma cells directly produce the receptor activator of nuclear factor kappaB ligand (RANKL) or induce RANKL in the bone marrow microenvironment?
Cancer research 2004;64(2):772-3; author reply 774-5.
2003: Richard Garand; Hervé Avet-Loiseau; F Accard; Philippe Moreau; Jean-Luc Harousseau; Régis Bataille
t(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma.
Leukemia 2003;17(10):2032-5.
2003: Sophie Barillé-Nion; Régis Bataille
New insights in myeloma-induced osteolysis.
Leukemia & lymphoma 2003;44(9):1463-7.
2003: Régis Bataille; Nelly Robillard; Catherine Pellat-Deceunynck; Martine Amiot
A cellular model for myeloma cell growth and maturation based on an intraclonal CD45 hierarchy.
Immunological reviews 2003;194():105-11.
2003: Nelly Robillard; Hervé Avet-Loiseau; Richard Garand; Philippe Moreau; Danielle Pineau; Marie-Josée Rapp; Jean-Luc Harousseau; Régis Bataille
CD20 is associated with a small mature plasma cell morphology and t(11;14) in multiple myeloma.
Blood 2003;102(3):1070-1.
2003: Nicola Giuliani; Simona Colla; Mirca Lazzaretti; Roberto Sala; Giovanni Roti; Cristina Mancini; Sabrina Bonomini; Paolo Lunghi; Magda Hojden; Giovenzio Genestreti; Mirija Svaldi; Paolo Coser; Patrizia Fattori; Gabriella Sammarelli; Gian C Gazzola; Régis Bataille; Camillo Almici; Cecilia Caramatti; Lina Mangoni; Vittorio Rizzoli
Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis.
Blood 2003;102(2):638-45.
2003: Florence Magrangeas; Valéry Nasser; Hervé Avet-Loiseau; Béatrice Loriod; Olivier Decaux; Samuel Granjeaud; François Bertucci; Daniel Birnbaum; Catherine Nguyen; Jean-Luc Harousseau; Régis Bataille; Rémi Houlgatte; Stéphane Minvielle
Gene expression profiling of multiple myeloma reveals molecular portraits in relation to the pathogenesis of the disease.
Blood 2003;101(12):4998-5006.
2003: Hervé Avet-Loiseau; Richard Garand; Laurence Lodé; Nelly Robillard; Régis Bataille
14q32 Translocations discriminate IgM multiple myeloma from Waldenstrom's macroglobulinemia.
Seminars in oncology 2003;30(2):153-5.
2003: Hervé Avet-Loiseau; Richard Garand; Laurence Lodé; Jean-Luc Harousseau; Régis Bataille
Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants.
Blood 2003;101(4):1570-1.
2003: Sophie Barillé-Nion; Bart Barlogie; Régis Bataille; P Leif Bergsagel; Joshua Epstein; Robert G Fenton; Joth Jacobson; W Michael Kuehl; John Shaughnessy; Guido Tricot
Advances in biology and therapy of multiple myeloma.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2003;():248-78.
2002: Nicola Giuliani; Simona Colla; Roberto Sala; Matteo Moroni; Mirca Lazzaretti; Silvia La Monica; Sabrina Bonomini; Magda Hojden; Gabriella Sammarelli; Sophie Barillè; Régis Bataille; Vittorio Rizzoli
Human myeloma cells stimulate the receptor activator of nuclear factor-kappa B ligand (RANKL) in T lymphocytes: a potential role in multiple myeloma bone disease.
Blood 2002;100(13):4615-21.
2002: Philippe Moreau; R Misbahi; Noël Milpied; Nadine Morineau; Béatrice Mahé; Magda Vigier; Marie-Josée Rapp; Régis Bataille; Jean-Luc Harousseau
Long-term results (12 years) of high-dose therapy in 127 patients with de novo multiple myeloma.
Leukemia 2002;16(9):1838-43.
2002: C Godon; J Proffitt; Nicole Dastugue; Marina Lafage-Pochitaloff; Marie-Joëlle Mozziconacci; Pascaline Talmant; M Hackbarth; Régis Bataille; Hervé Avet-Loiseau
Large deletions 5' to the ETO breakpoint are recurrent events in patients with t(8;21) acute myeloid leukemia.
Leukemia 2002;16(9):1752-4.
2002: Steven Le Gouill; Catherine Pellat-Deceunynck; Jean-Luc Harousseau; Marie-Josée Rapp; Nelly Robillard; Régis Bataille; Martine Amiot
Farnesyl transferase inhibitor R115777 induces apoptosis of human myeloma cells.
Leukemia 2002;16(9):1664-7.
2002: Philippe Moreau; Thierry Facon; Xavier Leleu; Nadine Morineau; Pauline Huyghe; Jean-Luc Harousseau; Régis Bataille; Hervé Avet-Loiseau
Recurrent 14q32 translocations determine the prognosis of multiple myeloma, especially in patients receiving intensive chemotherapy.
Blood 2002;100(5):1579-83.
2002: Stéphane Bezieau; Hervé Avet-Loiseau; Jean-Paul Moisan; Régis Bataille
Activating Ras mutations in patients with plasma-cell disorders: a reappraisal.
Blood 2002;100(3):1101-2; author reply 1103.
2002: Sophie Derenne; Brett P Monia; Nicholas Dean; Jennifer Taylor; Marie-Josée Rapp; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.
Blood 2002;100(1):194-9.
2002: Dominique Penther; Claude Preudhomme; Pascaline Talmant; Christophe Roumier; Alban Godon; Françoise Méchinaud; Noël Milpied; Régis Bataille; Hervé Avet-Loiseau
Amplification of AML1 gene is present in childhood acute lymphoblastic leukemia but not in adult, and is not associated with AML1 gene mutation.
Leukemia 2002;16(6):1131-4.
2002: Hervé Avet-Loiseau; Thierry Facon; Bernard Grosbois; Florence Magrangeas; Marie-Josée Rapp; Jean-Luc Harousseau; Stéphane Minvielle; Régis Bataille
Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation.
Blood 2002;99(6):2185-91.
2002: Patrice Chevallier; Dominique Penther; Hervé Avet-Loiseau; Nelly Robillard; Norbert Ifrah; Béatrice Mahé; Mohamed Hamidou; Hervé Maisonneuve; Philippe Moreau; Henri Jardel; Jean-Luc Harousseau; Régis Bataille; Richard Garand
CD38 expression and secondary 17p deletion are important prognostic factors in chronic lymphocytic leukaemia.
British journal of haematology 2002;116(1):142-50.
2001: Nicola Giuliani; Régis Bataille; Cristina Mancini; Mirca Lazzaretti; S Barillé
Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment.
Blood 2001;98(13):3527-33.
2001: Hervé Avet-Loiseau; F Gerson; Florence Magrangeas; Stéphane Minvielle; Jean-Luc Harousseau; Régis Bataille
Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors.
Blood 2001;98(10):3082-6.
2001: Stéphane Bezieau; Marie-Claire Devilder; Hervé Avet-Loiseau; Marie-Paule Mellerin; D Puthier; Erwan Pennarun; Marie-Josée Rapp; Jean-Luc Harousseau; Jean-Paul Moisan; Régis Bataille
High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis.
Human mutation 2001;18(3):212-24.
2001: W Thabard; Madeleine Collette; Régis Bataille; Martine Amiot
Protein kinase C delta and eta isoenzymes control the shedding of the interleukin 6 receptor alpha in myeloma cells.
The Biochemical journal 2001;358(Pt 1):193-200.
2001: W Thabard; Madeleine Collette; Marie-Paule Mellerin; D Puthier; S Barillé; Régis Bataille; Martine Amiot
IL-6 upregulates its own receptor on some human myeloma cell lines.
Cytokine 2001;14(6):352-6.
2001: G Jego; Régis Bataille; Catherine Pellat-Deceunynck
Interleukin-6 is a growth factor for nonmalignant human plasmablasts.
Blood 2001;97(6):1817-22.
2001: D Puthier; W Thabard; M Rapp; M Etrillard; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Interferon alpha extends the survival of human myeloma cells through an upregulation of the Mcl-1 anti-apoptotic molecule.
British journal of haematology 2001;112(2):358-63.
2001: Hervé Avet-Loiseau; A Daviet; Christophe Brigaudeau; E Callet-Bauchu; Christine Terré; Marina Lafage-Pochitaloff; F Désangles; S Ramond; Pascaline Talmant; Régis Bataille
Cytogenetic, interphase, and multicolor fluorescence in situ hybridization analyses in primary plasma cell leukemia: a study of 40 patients at diagnosis, on behalf of the Intergroupe Francophone du Myélome and the Groupe Français de Cytogénétique Hématologique.
Blood 2001;97(3):822-5.
2000: H Avet-Louseau; A Daviet; S Sauner; Régis Bataille
Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13.
British journal of haematology 2000;111(4):1116-7.
2000: S Barillé; Régis Bataille; Martine Amiot
The role of interleukin-6 and interleukin-6/interleukin-6 receptor-alpha complex in the pathogenesis of multiple myeloma.
European cytokine network 2000;11(4):546-51.
2000: C Godon; Pascaline Talmant; Richard Garand; F Accart; Régis Bataille; Hervé Avet-Loiseau
Deletion of 5q31 is observed in megakaryocytic cells in patients with myelodysplastic syndromes and a del(5q), including the 5q- syndrome.
Genes, chromosomes & cancer 2000;29(4):350-2.
2000: Nadine Morineau; X W Tang; Philippe Moreau; Noël Milpied; Béatrice Mahé; Régis Bataille; Jean-Luc Harousseau
Lack of benefit of CD34+ cell selected over non-selected peripheral blood stem cell transplantation in multiple myeloma: results of a single center study.
Leukemia 2000;14(10):1815-20.
2000: S Barillé; Madeleine Collette; W Thabard; Christophe Bleunven; Régis Bataille; Martine Amiot
Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells.
Cytokine 2000;12(9):1426-9.
2000: G Jego; Hervé Avet-Loiseau; Nelly Robillard; Philippe Moreau; Martine Amiot; Jean-Luc Harousseau; Catherine Pellat-Deceunynck; Régis Bataille
Reactive plasmacytoses in multiple myeloma during hematopoietic recovery with G- or GM-CSF.
Leukemia research 2000;24(7):627-30.
2000: Richard Garand; Surinder S Sahota; Hervé Avet-Loiseau; Pascaline Talmant; Nelly Robillard; Anne Moreau; Fanny Gaillard; F K Stevenson; Régis Bataille
IgG-secreting lymphoplasmacytoid leukaemia: a B-cell disorder with extensively mutated VH genes undergoing Ig isotype-switching frequently associated with trisomy 12.
British journal of haematology 2000;109(1):71-80.
2000: Steven Le Gouill; Pascaline Talmant; Noël Milpied; A Daviet; M Ancelot; Philippe Moreau; Jean-Luc Harousseau; Régis Bataille; Hervé Avet-Loiseau
Fluorescence in situ hybridization on peripheral-blood specimens is a reliable method to evaluate cytogenetic response in chronic myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(7):1533-8.
2000: Catherine Pellat-Deceunynck; Marie-Paule Mellerin; Nathalie Labarrière; G Jego; Agnès Moreau-Aubry; Jean-Luc Harousseau; Francine Jotereau; Régis Bataille
The cancer germ-line genes MAGE-1, MAGE-3 and PRAME are commonly expressed by human myeloma cells.
European journal of immunology 2000;30(3):803-9.
2000: Catherine Pellat-Deceunynck; G Jego; Nelly Robillard; F Accard; Martine Amiot; Régis Bataille
Reactive plasmacytoses, a model for studying the biology of human plasma cell progenitors and precursors.
The hematology journal : the official journal of the European Haematology Association / EHA 2000;1(6):362-6.
2000: Hervé Avet-Loiseau; Stéphane Minvielle; Marie-Paule Mellerin; Florence Magrangeas; Régis Bataille
14q32 chromosomal translocations: a hallmark of plasma cell dyscrasias?
The hematology journal : the official journal of the European Haematology Association / EHA 2000;1(5):292-4.
1999: Sophie Derenne; Martine Amiot; S Barillé; Madeleine Collette; Nelly Robillard; P Berthaud; Jean-Luc Harousseau; Régis Bataille
Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(12):2048-56.
1999: D Puthier; Régis Bataille; Martine Amiot
IL-6 up-regulates mcl-1 in human myeloma cells through JAK / STAT rather than ras / MAP kinase pathway.
European journal of immunology 1999;29(12):3945-50.
1999: S Barillé; Régis Bataille; Marie-Josée Rapp; Jean-Luc Harousseau; Martine Amiot
Production of metalloproteinase-7 (matrilysin) by human myeloma cells and its potential involvement in metalloproteinase-2 activation.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(10):5723-8.
1999: D Puthier; Sophie Derenne; S Barillé; Philippe Moreau; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Mcl-1 and Bcl-xL are co-regulated by IL-6 in human myeloma cells.
British journal of haematology 1999;107(2):392-5.
1999: Hervé Avet-Loiseau; JY Li; Nadine Morineau; Thierry Facon; Christophe Brigaudeau; Jean-Luc Harousseau; B Grosbois; Régis Bataille
Monosomy 13 is associated with the transition of monoclonal gammopathy of undetermined significance to multiple myeloma. Intergroupe Francophone du Myélome.
Blood 1999;94(8):2583-9.
1999: Olivier Couturier; Alain Faivre-Chauvet; IV Filippovich; Philippe Thédrez; Catherine Saï-Maurel; Manuel Bardiès; A K Mishra; M Gauvrit; G Blain; Christos Apostolidis; Roger Molinet; J C Abbe; Régis Bataille; John Wijdenes; Jean-François Chatal; Michel Chérel
Validation of 213Bi-alpha radioimmunotherapy for multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3165s-3170s.
1999: W Thabard; S Barillé; Madeleine Collette; Jean-Luc Harousseau; Marie-Josée Rapp; Régis Bataille; Martine Amiot
Myeloma cells release soluble interleukin-6Ralpha in relation to disease progression by two distinct mechanisms: alternative splicing and proteolytic cleavage.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10):2693-7.
1999: Hervé Avet-Loiseau; C Godon; JY Li; A Daviet; Marie-Paule Mellerin; Pascaline Talmant; Jean-Luc Harousseau; Régis Bataille
Amplification of the 11q23 region in acute myeloid leukemia.
Genes, chromosomes & cancer 1999;26(2):166-70.
1999: Hervé Avet-Loiseau; Thierry Facon; A Daviet; C Godon; Marie-Josée Rapp; Jean-Luc Harousseau; Bernard Grosbois; Régis Bataille
14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome.
Cancer research 1999;59(18):4546-50.
1999: Hervé Avet-Loiseau; J Y Li; C Godon; Nadine Morineau; A Daviet; Jean-Luc Harousseau; T Facon; Régis Bataille
P53 deletion is not a frequent event in multiple myeloma.
British journal of haematology 1999;106(3):717-9.
1999: S Barillé; W Thabard; Nelly Robillard; Philippe Moreau; Danielle Pineau; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
CD130 rather than CD126 expression is associated with disease activity in multiple myeloma.
British journal of haematology 1999;106(2):532-5.
1999: Surinder S Sahota; Richard Garand; R Mahroof; A Smith; Nadine Juge-Morineau; Freda K Stevenson; Régis Bataille
V(H) gene analysis of IgM-secreting myeloma indicates an origin from a memory cell undergoing isotype switch events.
Blood 1999;94(3):1070-6.
1999: G Jego; Nelly Robillard; D Puthier; Martine Amiot; F Accard; Danielle Pineau; Jean-Luc Harousseau; Régis Bataille; Catherine Pellat-Deceunynck
Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells.
Blood 1999;94(2):701-12.
1999: Philippe Moreau; Noël Milpied; Béatrice Mahé; Nadine Juge-Morineau; Marie-Josée Rapp; Régis Bataille; Jean-Luc Harousseau
Melphalan 220 mg/m2 followed by peripheral blood stem cell transplantation in 27 patients with advanced multiple myeloma.
Bone marrow transplantation 1999;23(10):1003-6.
1999: JY Li; F Gaillard; A Moreau; Jean-Luc Harousseau; C Laboisse; Noël Milpied; Régis Bataille; Hervé Avet-Loiseau
Detection of translocation t(11;14)(q13;q32) in mantle cell lymphoma by fluorescence in situ hybridization.
The American journal of pathology 1999;154(5):1449-52.
1999: Catherine Pellat-Deceunynck; G Jego; Jean-Luc Harousseau; H Vié; Régis Bataille
Isolation of human lymphocyte antigens class I-restricted cytotoxic T lymphocytes against autologous myeloma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):705-9.
1999: D Puthier; Catherine Pellat-Deceunynck; S Barillé; Nelly Robillard; Marie-Josée Rapp; Nadine Juge-Morineau; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Differential expression of Bcl-2 in human plasma cell disorders according to proliferation status and malignancy.
Leukemia 1999;13(2):289-94.
1999: Hervé Avet-Loiseau; Christophe Brigaudeau; Nadine Morineau; Pascaline Talmant; J L Laï; A Daviet; JY Li; V Praloran; Marie-Josée Rapp; Jean-Luc Harousseau; Thierry Facon; Régis Bataille
High incidence of cryptic translocations involving the Ig heavy chain gene in multiple myeloma, as shown by fluorescence in situ hybridization.
Genes, chromosomes & cancer 1999;24(1):9-15.
1998: Hervé Avet-Loiseau; JY Li; Thierry Facon; Christophe Brigaudeau; Nadine Morineau; F Maloisel; Marie-Josée Rapp; Pascaline Talmant; Franck Trimoreau; Arnaud Jaccard; Jean-Luc Harousseau; Régis Bataille
High incidence of translocations t(11;14)(q13;q32) and t(4;14)(p16;q32) in patients with plasma cell malignancies.
Cancer research 1998;58(24):5640-5.
1998: Catherine Pellat-Deceunynck; S Barillé; G Jego; D Puthier; Nelly Robillard; Danielle Pineau; Marie-Josée Rapp; Jean-Luc Harousseau; Martine Amiot; Régis Bataille
The absence of CD56 (NCAM) on malignant plasma cells is a hallmark of plasma cell leukemia and of a special subset of multiple myeloma.
Leukemia 1998;12(12):1977-82.
1998: Hervé Avet-Loiseau; Richard Garand; Fanny Gaillard; A Daviet; Marie-Paule Mellerin; Nelly Robillard; I Bouyge; S Arcot; M Batzer; Pascaline Talmant; Jean-Luc Harousseau; Noël Milpied; Régis Bataille
Detection of t(11;14) using interphase molecular cytogenetics in mantle cell lymphoma and atypical chronic lymphocytic leukemia.
Genes, chromosomes & cancer 1998;23(2):175-82.
1998: Nelly Robillard; G Jego; Catherine Pellat-Deceunynck; Danielle Pineau; D Puthier; Marie-Paule Mellerin; S Barillé; Marie-Josée Rapp; Jean-Luc Harousseau; Martine Amiot; Régis Bataille
CD28, a marker associated with tumoral expansion in multiple myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(6):1521-6.
1998: Surinder S Sahota; Richard Garand; Régis Bataille; A J Smith; Freda K Stevenson
VH gene analysis of clonally related IgM and IgG from human lymphoplasmacytoid B-cell tumors with chronic lymphocytic leukemia features and high serum monoclonal IgG.
Blood 1998;91(1):238-43.
1997: Sylvie Hermouet; A E Niaussat; A Briec; Danielle Pineau; Nelly Robillard; Régis Bataille; Noël Milpied; Jean-Luc Harousseau; Béatrice Mahé
Analysis of platelet recovery after autologous transplantation with G-CSF mobilized CD34+ cells purified from leukapheresis products.
Hematology and cell therapy 1997;39(6):317-25.
1997: M Paszek-Vigier; Pascaline Talmant; Françoise Méchinaud; Richard Garand; Jean-Luc Harousseau; Régis Bataille; Hervé Avet-Loiseau
Comparative genomic hybridization is a powerful tool, complementary to cytogenetics, to identify chromosomal abnormalities in childhood acute lymphoblastic leukaemia.
British journal of haematology 1997;99(3):589-96.
1997: S Barillé; C Akhoundi; Madeleine Collette; Marie-Paule Mellerin; Marie-Josée Rapp; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Metalloproteinases in multiple myeloma: production of matrix metalloproteinase-9 (MMP-9), activation of proMMP-2, and induction of MMP-1 by myeloma cells.
Blood 1997;90(4):1649-55.
1997: Hervé Avet-Loiseau; L E Andree-Ashley; D Moore; Marie-Paule Mellerin; James Feusner; Régis Bataille; Maria G Pallavicini
Molecular cytogenetic abnormalities in multiple myeloma and plasma cell leukemia measured using comparative genomic hybridization.
Genes, chromosomes & cancer 1997;19(2):124-33.
1997: Hervé Avet-Loiseau; Magda Vigier; Anne Moreau; Marie-Paule Mellerin; Fanny Gaillard; Jean-Luc Harousseau; Régis Bataille; Noël Milpied
Comparative genomic hybridization detects genomic abnormalities in 80% of follicular lymphomas.
British journal of haematology 1997;97(1):119-22.
1997: Nadine Juge-Morineau; Jean-Luc Harousseau; Martine Amiot; Régis Bataille
The retinoblastoma susceptibility gene RB-1 in multiple myeloma.
Leukemia & lymphoma 1997;24(3-4):229-37.
1997: Régis Bataille
New insights in the clinical biology of multiple myeloma.
Seminars in hematology 1997;34(1 Suppl 1):23-8.
1996: D Puthier; Régis Bataille; S Barillé; Marie-Paule Mellerin; Jean-Luc Harousseau; A Ponzio; Nelly Robillard; J Wijdenes; Martine Amiot
Myeloma cell growth arrest, apoptosis, and interleukin-6 receptor modulation induced by EB1089, a vitamin D3 derivative, alone or in association with dexamethasone.
Blood 1996;88(12):4659-66.
1996: Philippe Moreau; Marie-France Kergueris; Noël Milpied; S Le Tortorec; Béatrice Mahé; Claude-Eric Bulabois; Marie-Josée Rapp; C Larousse; Régis Bataille; Jean-Luc Harousseau
A pilot study of 220 mg/m2 melphalan followed by autologous stem cell transplantation in patients with advanced haematological malignancies: pharmacokinetics and toxicity.
British journal of haematology 1996;95(3):527-30.
1996: Hervé Avet-Loiseau; Marie-Claire Devilder; Richard Garand; I Bouyge; Marie-Josée Rapp; Noël Milpied; Jean-Luc Harousseau; Jean-Paul Moisan; Régis Bataille
13q14 deletions are not primary events in B-cell chronic lymphocytic leukemia: a study of 100 patients using fluorescence in situ hybridization.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(10):1673-7.
1996: Catherine Pellat-Deceunynck; Martine Amiot; Nelly Robillard; J Wijdenes; Régis Bataille
CD11a-CD18 and CD102 interactions mediate human myeloma cell growth arrest induced by CD40 stimulation.
Cancer research 1996;56(8):1909-16.
1996: S Barille; Catherine Pellat-Deceunynck; Régis Bataille; Martine Amiot
Ectopic secretion of osteocalcin, the major non-collagenous bone protein, by the myeloma cell line NCI-H929.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(4):466-71.
1996: Béatrice Mahé; Noël Milpied; Sylvie Hermouet; Nelly Robillard; Philippe Moreau; S Letortorec; Marie-Josée Rapp; Régis Bataille; Jean-Luc Harousseau
G-CSF alone mobilizes sufficient peripheral blood CD34+ cells for positive selection in newly diagnosed patients with myeloma.
British journal of haematology 1996;92(2):263-8.
1995: Nadine Juge-Morineau; Marie-Paule Mellerin; S Francois; Marie-Josée Rapp; Jean-Luc Harousseau; Martine Amiot; Régis Bataille
High incidence of deletions but infrequent inactivation of the retinoblastoma gene in human myeloma cells.
British journal of haematology 1995;91(3):664-7.
1995: S Barillé; Madeleine Collette; Régis Bataille; Martine Amiot
Myeloma cells upregulate interleukin-6 secretion in osteoblastic cells through cell-to-cell contact but downregulate osteocalcin.
Blood 1995;86(8):3151-9.
1995: Michel Chérel; M Sorel; B Lebeau; S Dubois; Jean-François Moreau; Régis Bataille; Stéphane Minvielle; Yannick Jacques
Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11.
Blood 1995;86(7):2534-40.
1995: Catherine Pellat-Deceunynck; S Barillé; D Puthier; Marie-Josée Rapp; Jean-Luc Harousseau; Régis Bataille; Martine Amiot
Adhesion molecules on human myeloma cells: significant changes in expression related to malignancy, tumor spreading, and immortalization.
Cancer research 1995;55(16):3647-53.
1995: Régis Bataille
The mechanisms of bone lesions in human plasmacytomas.
Stem cells (Dayton, Ohio) 1995;13 Suppl 2():40-7.
1995: Régis Bataille; D Chappard; M Basle
Excessive bone resorption in human plasmacytomas: direct induction by tumour cells in vivo.
British journal of haematology 1995;90(3):721-4.
1995: Nadine Juge-Morineau; S François; D Puthier; A Godard; Régis Bataille; Martine Amiot
The gp 130 family cytokines IL-6, LIF and OSM but not IL-11 can reverse the anti-proliferative effect of dexamethasone on human myeloma cells.
British journal of haematology 1995;90(3):707-10.
1995: Marie-Claire Devilder; S François; C Bosic; A Moreau; M P Mellerin; D Le Paslier; Régis Bataille; Jean-Paul Moisan
Deletion cartography around the D13S25 locus in B cell chronic lymphocytic leukemia and accurate mapping of the involved tumor suppressor gene.
Cancer research 1995;55(6):1355-7.
1994: Catherine Pellat-Deceunynck; Régis Bataille; Nelly Robillard; Jean-Luc Harousseau; Marie-Josée Rapp; Nadine Juge-Morineau; J Wijdenes; Martine Amiot
Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells.
Blood 1994;84(8):2597-603.
1994: Richard Garand; Nelly Robillard; Régis Bataille
CD72 is constantly expressed in chronic lymphocytic leukemia and other B-cell lymphoproliferative disorders.
Leukemia research 1994;18(8):651-2.
1993: Régis Bataille; B Klein
[Human plasmacytoma from biology to clinical practice].
Nouvelle revue française d'hématologie 1993;35(3):179-82.
1991: Régis Bataille; Daniel Chappard; C Marcelli; P Dessauw; P Baldet; J Sany; Christian Alexandre
Recruitment of new osteoblasts and osteoclasts is the earliest critical event in the pathogenesis of human multiple myeloma.
The Journal of clinical investigation 1991;88(1):62-6.
1990: X G Zhang; Régis Bataille; M Jourdan; Sem Saeland; Jacques Banchereau; Patrice Mannoni; Bernard Klein
Granulocyte-macrophage colony-stimulating factor synergizes with interleukin-6 in supporting the proliferation of human myeloma cells.
Blood 1990;76(12):2599-605.
1990: Régis Bataille; Daniel Chappard; C Marcelli; J F Rossi; P Dessauw; P Baldet; J Sany; Christian Alexandre
Osteoblast stimulation in multiple myeloma lacking lytic bone lesions.
British journal of haematology 1990;76(4):484-7.
1989: Régis Bataille; M Jourdan; X G Zhang; Bernard Klein
Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.
The Journal of clinical investigation 1989;84(6):2008-11.
1989: Régis Bataille; Daniel Chappard; C Marcelli; P Dessauw; J Sany; P Baldet; Christian Alexandre
Mechanisms of bone destruction in multiple myeloma: the importance of an unbalanced process in determining the severity of lytic bone disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(12):1909-14.
1988: C Marcelli; Daniel Chappard; J F Rossi; J Jaubert; Christian Alexandre; P Dessauw; P Baldet; Régis Bataille
Histologic evidence of an abnormal bone remodeling in B-cell malignancies other than multiple myeloma.
Cancer 1988;62(6):1163-70.
1986: Régis Bataille; D Chappard; C Alexandre; P Dessauw; J Sany
Importance of quantitative histology of bone changes in monoclonal gammopathy.
British journal of cancer 1986;53(6):805-10.