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John Martin

Research Profile

Chemicals & Drugs

Anatomy

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Physiology

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Publications

TOP 3
Nalini H Kulkarni; Tao Wei; Amar Kumar; Ernst Dow; Trent R Stewart; Jianyong Shou; Mathias N'Cho; Diane L Sterchi; Bruce D Gitter; Richard E Higgs; David L Halladay; Thomas A Engler; T John Martin; Henry Bryant; Yanfei L Ma; Jude E Onyia
Changes in osteoblast, chondrocyte, and adipocyte lineages mediate the bone anabolic actions of PTH and small molecule GSK-3 inhibitor.
Nalini H Kulkarni; Jude E Onyia; Qingqiang Zeng; Xioayan Tian; Min Liu; David L Halladay; Charles A Frolik; Thomas A Engler; Tao Wei; Aidas Kriauciunas; T John Martin; Masahiko Sato; Henry Bryant; Yanfei L Ma
Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.
Nalini H Kulkarni; David L Halladay; Rebecca R Miles; L M Gilbert; Charles A Frolik; Rachelle J Sells Galvin; T John Martin; M T Gillespie; Jude E Onyia
Effects of parathyroid hormone on Wnt signaling pathway in bone.

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All Publications

2007: Nalini H Kulkarni; Tao Wei; Amar Kumar; Ernst Dow; Trent R Stewart; Jianyong Shou; Mathias N'Cho; Diane L Sterchi; Bruce D Gitter; Richard E Higgs; David L Halladay; Thomas A Engler; T John Martin; Henry Bryant; Yanfei L Ma; Jude E Onyia
Changes in osteoblast, chondrocyte, and adipocyte lineages mediate the bone anabolic actions of PTH and small molecule GSK-3 inhibitor.
Journal of cellular biochemistry 2007;102(6):1504-18.
2006: Nalini H Kulkarni; Jude E Onyia; Qingqiang Zeng; Xioayan Tian; Min Liu; David L Halladay; Charles A Frolik; Thomas A Engler; Tao Wei; Aidas Kriauciunas; T John Martin; Masahiko Sato; Henry Bryant; Yanfei L Ma
Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(6):910-20.
2005: Nalini H Kulkarni; David L Halladay; Rebecca R Miles; L M Gilbert; Charles A Frolik; Rachelle J Sells Galvin; T John Martin; M T Gillespie; Jude E Onyia
Effects of parathyroid hormone on Wnt signaling pathway in bone.
Journal of cellular biochemistry 2005;95(6):1178-90.
2004: Jude E Onyia; Rachelle J Sells Galvin; Yanfei L Ma; David L Halladay; Rebecca R Miles; Xuhao Yang; Tina Fuson; Ricky L Cain; Qing Qiang Zeng; Srinivasan Chandrasekhar; Renee Emkey; Yanping Xu; Kannan Thirunavukkarasu; Henry Bryant; T John Martin
Novel and selective small molecule stimulators of osteoprotegerin expression inhibit bone resorption.
The Journal of pharmacology and experimental therapeutics 2004;309(1):369-79.
2003: Enrique Alvarez; Michael Westmore; Rachelle J Sells Galvin; Crystal L Clapp; Eileen L Considine; Shawn J Smith; Kristan A Keyes; Philip W Iversen; Dawn M Delafuente; Shola Sulaimon; Carmen Zambrano; Linda Ma; Masahiko Sato; T John Martin; Beverly A Teicher; Elizabeth Galbreath
Properties of bisphosphonates in the 13762 rat mammary carcinoma model of tumor-induced bone resorption.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5705-13.
2002: Xuhao Yang; David L Halladay; Jude E Onyia; T John Martin; Srinivasan Chandrasekhar
Protein Kinase C is a mediator of the synthesis and secretion of osteoprotegerin in osteoblast-like cells.
Biochemical and biophysical research communications 2002;290(1):42-6.
2001: Kannan Thirunavukkarasu; Rebecca R Miles; David L Halladay; Xuhao Yang; Rachelle J Sells Galvin; Srinivasan Chandrasekhar; T John Martin; Jude E Onyia
Stimulation of osteoprotegerin (OPG) gene expression by transforming growth factor-beta (TGF-beta). Mapping of the OPG promoter region that mediates TGF-beta effects.
The Journal of biological chemistry 2001;276(39):36241-50.
2001: Yanfei L Ma; Ricky L Cain; David L Halladay; Xuhao Yang; Qingqiang Zeng; Rebecca R Miles; Srinivasan Chandrasekhar; T John Martin; Jude E Onyia
Catabolic effects of continuous human PTH (1--38) in vivo is associated with sustained stimulation of RANKL and inhibition of osteoprotegerin and gene-associated bone formation.
Endocrinology 2001;142(9):4047-54.
2001: David L Halladay; Rebecca R Miles; Kannan Thirunavukkarasu; Srinivasan Chandrasekhar; T John Martin; Jude E Onyia
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.
Journal of cellular biochemistry 2001;84(1):1-11.
2000: Kannan Thirunavukkarasu; David L Halladay; Rebecca R Miles; Xuhao Yang; Rachelle J Sells Galvin; Srinivasan Chandrasekhar; T John Martin; Jude E Onyia
The osteoblast-specific transcription factor Cbfa1 contributes to the expression of osteoprotegerin, a potent inhibitor of osteoclast differentiation and function.
The Journal of biological chemistry 2000;275(33):25163-72.
2000: Jude E Onyia; Rebecca R Miles; X Yang; David L Halladay; J Hale; A Glasebrook; D McClure; G Seno; L Churgay; Srinivasan Chandrasekhar; T John Martin
In vivo demonstration that human parathyroid hormone 1-38 inhibits the expression of osteoprotegerin in bone with the kinetics of an immediate early gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(5):863-71.