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Wim Martinet

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Veerle Matheeussen; Simon Scharpé; Pieter Van der Veken; Sebastiaan Van Goethem; Yannick Waumans; Koen Augustyns; Guido R Y De Meyer; Wim Martinet; Ingrid De Meester
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
Johanna T H van Langen; Guido R Y De Meyer; Paul Fransen; Wim Martinet; Dorien M Schrijvers; Cor E Van Hove; Hidde Bult
Contribution of α-adrenoceptor stimulation by phenylephrine to basal nitric oxide production in the isolated mouse aorta.
Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Hidde Bult; Guido R Y De Meyer
Immunohistochemical analysis of macroautophagy: recommendations and limitations.

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All Publications

2013: Veerle Matheeussen; Simon Scharpé; Pieter Van der Veken; Sebastiaan Van Goethem; Yannick Waumans; Koen Augustyns; Guido R Y De Meyer; Wim Martinet; Ingrid De Meester
Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis.
Basic research in cardiology 2013;108(3):350.
2013: Johanna T H van Langen; Guido R Y De Meyer; Paul Fransen; Wim Martinet; Dorien M Schrijvers; Cor E Van Hove; Hidde Bult
Contribution of α-adrenoceptor stimulation by phenylephrine to basal nitric oxide production in the isolated mouse aorta.
Journal of cardiovascular pharmacology 2013;61(4):318-23.
2013: Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Hidde Bult; Guido R Y De Meyer
Immunohistochemical analysis of macroautophagy: recommendations and limitations.
Autophagy 2013;9(3):386-402.
2013: Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Stefan Verheye; Inge De Meyer; Guido R Y De Meyer
Drug-induced macrophage autophagy in atherosclerosis: for better or worse?
Basic research in cardiology 2013;108(1):321.
2012: Johanna van Langen; Guido R Y De Meyer; Paul Fransen; Wim Martinet; Dorien M Schrijvers; Cor E Van Hove; Hidde Bult
Selective loss of basal but not receptor-stimulated relaxation by endothelial nitric oxide synthase after isolation of the mouse aorta.
European journal of pharmacology 2012;696(1-3):111-9.
2012: Inge De Meyer; Wim Martinet; Guido R Y De Meyer
Therapeutic strategies to deplete macrophages in atherosclerotic plaques.
British journal of clinical pharmacology 2012;74(2):246-63.
2012: Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Ilse Van Brussel; Stefan Verheye; Hidde Bult; Inge De Meyer; Guido R Y De Meyer
Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoid.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(5):1228-35.
2012: Wim Martinet; Dorien M Schrijvers; Guido R Y De Meyer
Molecular and cellular mechanisms of macrophage survival in atherosclerosis.
Basic research in cardiology 2012;107(6):297.
2012: Paul Fransen; Wim Martinet; Dorien M Schrijvers; Cor E Van Hove; Johanna van Langen; Guido R Y De Meyer; Hidde Bult
Contribution of transient and sustained calcium influx, and sensitization to depolarization-induced contractions of the intact mouse aorta.
BMC physiology 2012;12():9.
2012: Ilse Van Brussel; Christiaan J Vrints; Dirk Adriaensen; Johan M Bosmans; Paul Cos; Maartje Deschacht; Louis Maes; Wim Martinet; Isabel Pintelon; Kathy Schnorbusch; Dorien M Schrijvers; Hidde Bult
Transcript and protein analysis reveals better survival skills of monocyte-derived dendritic cells compared to monocytes during oxidative stress.
PloS one 2012;7(8):e43357.
2012: Inge De Meyer; Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Hidde Bult; Guido R Y De Meyer
Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques.
Basic research in cardiology 2012;107(3):269.
2011: Dorien M Schrijvers; Guido R Y De Meyer; Wim Martinet
Autophagy in atherosclerosis: a potential drug target for plaque stabilization.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(12):2787-91.
2011: Wim Martinet; Dorien M Schrijvers; Guido R Y De Meyer
Necrotic cell death in atherosclerosis.
Basic research in cardiology 2011;106(5):749-60.
2011: Wim Martinet; Dorien M Schrijvers; Guido R Y De Meyer
Pharmacological modulation of cell death in atherosclerosis: a promising approach towards plaque stabilization?
British journal of pharmacology 2011;164(1):1-13.
2011: Tim J L Van De Parre; Pieter-Jan D F Guns; Paul Fransen; Wim Martinet; Hidde Bult; Arnold G Herman; Guido De Meyer
Attenuated atherogenesis in apolipoprotein E-deficient mice lacking amyloid precursor protein.
Atherosclerosis 2011;216(1):54-8.
2011: Inge De Meyer; Wim Martinet; Cor E Van Hove; Dorien M Schrijvers; Vicky Y Hoymans; Luc Van Vaeck; Paul Fransen; Hidde Bult; Guido De Meyer
Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques.
British journal of pharmacology 2011;162(6):1410-23.
2011: Tim Van Assche; Jan Hendrickx; Herta M Crauwels; Pieter-Jan Guns; Wim Martinet; Paul Fransen; Martine Raes; Hidde Bult
Transcription profiles of aortic smooth muscle cells from atherosclerosis-prone and -resistant regions in young apolipoprotein E-deficient mice before plaque development.
Journal of vascular research 2011;48(1):31-42.
2010: Guido R Y De Meyer; Gilles W De Keulenaer; Wim Martinet
Role of autophagy in heart failure associated with aging.
Heart failure reviews 2010;15(5):423-30.
2010: Maartje Deschacht; Tessa Horemans; Wim Martinet; Hidde Bult; Louis Maes; Paul Cos
Comparative EPR study of different macrophage types stimulated for superoxide and nitric oxide production.
Free radical research 2010;44(7):763-72.
2010: Wim Martinet; Inge De Meyer; Nathalie Cools; Vincent Timmerman; Hidde Bult; Johan Bosmans; Guido De Meyer
Cell death-mediated cleavage of the attraction signal p43 in human atherosclerosis: implications for plaque destabilization.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1415-22.
2009: Guido De Meyer; Wim Martinet
Autophagy in the cardiovascular system.
Biochimica et biophysica acta 2009;1793(9):1485-95.
2009: Wim Martinet; Valerie Croons; Arnold G Herman; Guido De Meyer
Apoptosis does not mediate macrophage depletion in rabbit atherosclerotic plaques after dietary lipid lowering.
Annals of the New York Academy of Sciences 2009;1171():365-71.
2009: Wim Martinet; Patrizia Agostinis; Barbara Vanhoecke; Michael Dewaele; Guido De Meyer
Autophagy in disease: a double-edged sword with therapeutic potential.
Clinical science (London, England : 1979) 2009;116(9):697-712.
2009: Wim Martinet; Dorien M Schrijvers; Jean-Pierre Timmermans; Arnold G Herman; Guido De Meyer
Phagocytosis of bacteria is enhanced in macrophages undergoing nutrient deprivation.
The FEBS journal 2009;276(8):2227-40.
2009: Nathalie E Ruyssers; Benedicte Y De Winter; Joris G De Man; Alex Loukas; Mark S Pearson; Joel V Weinstock; RM Van Den Bossche; Wim Martinet; Paul A Pelckmans; Tom G Moreels
Therapeutic potential of helminth soluble proteins in TNBS-induced colitis in mice.
Inflammatory bowel diseases 2009;15(4):491-500.
2009: Wim Martinet; Guido De Meyer
Autophagy in atherosclerosis: a cell survival and death phenomenon with therapeutic potential.
Circulation research 2009;104(3):304-17.
2008: Wim Martinet; Guido De Meyer
Autophagy in atherosclerosis.
Current atherosclerosis reports 2008;10(3):216-23.
2008: Valerie Croons; Wim Martinet; Arnold G Herman; Guido De Meyer
Differential effect of the protein synthesis inhibitors puromycin and cycloheximide on vascular smooth muscle cell viability.
The Journal of pharmacology and experimental therapeutics 2008;325(3):824-32.
2008: Tim J L Van De Parre; Wim Martinet; Stefan Verheye; Mark M Kockx; Glenn Van Langenhove; Arnold G Herman; Guido De Meyer
Mitochondrial uncoupling protein 2 mediates temperature heterogeneity in atherosclerotic plaques.
Cardiovascular research 2008;77(2):425-31.
2007: Wim Martinet; Michiel Knaapen; Mark M Kockx; Guido De Meyer
Autophagy in cardiovascular disease.
Trends in molecular medicine 2007;13(11):482-91.
2007: Wim Martinet; V Croons; Jean-Pierre Timmermans; Arnold G Herman; Guido De Meyer
Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress.
British journal of pharmacology 2007;152(4):493-500.
2007: Elke Fordel; Liesbet Thijs; Wim Martinet; Dorien Schrijvers; Luc Moens; Sylvia Dewilde
Anoxia or oxygen and glucose deprivation in SH-SY5Y cells: a step closer to the unraveling of neuroglobin and cytoglobin functions.
Gene 2007;398(1-2):114-22.
2007: Tim J L Van De Parre; Wim Martinet; Stefan Verheye; Guido De Meyer
Uncoupling protein 2-mediated thermogenesis in vulnerable atherosclerotic plaques.
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2007;3(2):275-9.
2007: Wim Martinet; Stefan Verheye; Guido De Meyer
Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy.
Autophagy 2007;3(3):241-4.
2007: Wim Martinet; Guido De Meyer
Selective depletion of macrophages in atherosclerotic plaques: myth, hype, or reality?
Circulation research 2007;100(6):751-3.
2007: Valerie Croons; Wim Martinet; Arnold G Herman; Jean-Pierre Timmermans; Guido De Meyer
Selective clearance of macrophages in atherosclerotic plaques by the protein synthesis inhibitor cycloheximide.
The Journal of pharmacology and experimental therapeutics 2007;320(3):986-93.
2007: Stefan Verheye; Wim Martinet; Mark M Kockx; Michiel Knaapen; Koen Salu; Jean-Pierre Timmermans; Jeffrey T Ellis; deborah kilpatrick; Guido De Meyer
Selective clearance of macrophages in atherosclerotic plaques by autophagy.
Journal of the American College of Cardiology 2007;49(6):706-15.
2007: Wim Martinet; Stefan Verheye; Guido De Meyer
Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death.
Trends in cardiovascular medicine 2007;17(2):69-75.
2007: Dorien M Schrijvers; Guido De Meyer; Arnold G Herman; Wim Martinet
Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability.
Cardiovascular research 2007;73(3):470-80.
2007: Dorien M Schrijvers; Guido De Meyer; Mark M Kockx; Arnold G Herman; Wim Martinet
Comparison of apoptosis detection markers combined with macrophage immunostaining to study phagocytosis of apoptotic cells in situ.
Biomarker insights 2007;1():193-200.
2006: Elke Fordel; Liesbet Thijs; Wim Martinet; Marc Lenjou; Tilmann Laufs; Dirk R Van Bockstaele; Luc Moens; Sylvia Dewilde
Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death.
Neuroscience letters 2006;410(2):146-51.
2006: Wim Martinet; Dorien M Schrijvers; Arnold G Herman; Guido De Meyer
z-VAD-fmk-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization.
Autophagy 2006;2(4):312-4.
2006: Marie-Berthe Maes; Wim Martinet; Dorien M Schrijvers; Pieter Van der Veken; Guido De Meyer; Koen Augustyns; Anne-Marie Lambeir; Simon Scharpé; Ingrid De Meester
Dipeptidyl peptidase II and leukocyte cell death.
Biochemical pharmacology 2006;72(1):70-9.
2006: Wim Martinet; Guido De Meyer; Jean-Pierre Timmermans; Arnold G Herman; Mark M Kockx
Macrophages but not smooth muscle cells undergo benzyloxycarbonyl-Val-Ala-DL-Asp(O-Methyl)-fluoromethylketone-induced nonapoptotic cell death depending on receptor-interacting protein 1 expression: implications for the stabilization of macrophage-rich atherosclerotic plaques.
The Journal of pharmacology and experimental therapeutics 2006;317(3):1356-64.
2006: Dominique M Jans; Wim Martinet; T J L Van De Parre; Arnold G Herman; Hidde Bult; Mark M Kockx; Guido De Meyer
Processing of amyloid precursor protein as a biochemical link between atherosclerosis and Alzheimer's disease.
Cardiovascular & hematological disorders drug targets 2006;6(1):21-34.
2006: Wim Martinet; Guido De Meyer; Luc Andries; Arnold G Herman; Mark M Kockx
Detection of autophagy in tissue by standard immunohistochemistry: possibilities and limitations.
Autophagy 2006;2(1):55-7.
2006: Wim Martinet; Guido De Meyer; Luc Andries; Arnold G Herman; Mark M Kockx
In situ detection of starvation-induced autophagy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(1):85-96.
2005: Wim Martinet; Guido De Meyer; Arnold G Herman; Mark M Kockx
Amino acid deprivation induces both apoptosis and autophagy in murine C2C12 muscle cells.
Biotechnology letters 2005;27(16):1157-63.
2005: Dorien M Schrijvers; Guido De Meyer; Mark M Kockx; Arnold G Herman; Wim Martinet
Phagocytosis of apoptotic cells by macrophages is impaired in atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(6):1256-61.
2005: Tim J L Van De Parre; Wim Martinet; Dorien M Schrijvers; Arnold G Herman; Guido De Meyer
mRNA but not plasmid DNA is efficiently transfected in murine J774A.1 macrophages.
Biochemical and biophysical research communications 2005;327(1):356-60.
2005: Wim Martinet; Guido De Meyer; Arnold G Herman; Mark M Kockx
RNA damage in human atherosclerosis: pathophysiological significance and implications for gene expression studies.
RNA biology 2005;2(1):4-7.
2004: Wim Martinet; Martine De Bie; Dorien M Schrijvers; Guido De Meyer; Arnold G Herman; Mark M Kockx
7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2296-301.
2004: Vicky Y Hoymans; Johan M Bosmans; Dominique Ursi; Wim Martinet; Floris L Wuyts; Eric Van Marck; Martin Altwegg; Christiaan Vrints; Margareta Ieven
Immunohistostaining assays for detection of Chlamydia pneumoniae in atherosclerotic arteries indicate cross-reactions with nonchlamydial plaque constituents.
Journal of clinical microbiology 2004;42(7):3219-24.
2004: Wim Martinet; Guido De Meyer; A G Herman; M M Kockx
Reactive oxygen species induce RNA damage in human atherosclerosis.
European journal of clinical investigation 2004;34(5):323-7.
2004: Dorien M Schrijvers; Wim Martinet; Guido De Meyer; Luc Andries; Arnold G Herman; Mark M Kockx
Flow cytometric evaluation of a model for phagocytosis of cells undergoing apoptosis.
Journal of immunological methods 2004;287(1-2):101-8.
2004: Dominique M Jans; Wim Martinet; Marianne Fillet; Mark M Kockx; Marie-Paule Merville; Hidde Bult; Arnold G Herman; Guido De Meyer
Effect of non-steroidal anti-inflammatory drugs on amyloid-beta formation and macrophage activation after platelet phagocytosis.
Journal of cardiovascular pharmacology 2004;43(3):462-70.
2004: Wim Martinet; Vanessa Abbeloos; Nathalie Van Acker; Guido De Meyer; Arnold G Herman; Mark M Kockx
Western blot analysis of a limited number of cells: a valuable adjunct to proteome analysis of paraffin wax-embedded, alcohol-fixed tissue after laser capture microdissection.
The Journal of pathology 2004;202(3):382-8.
2004: Wim Martinet; Dorien M Schrijvers; Guido De Meyer; Arnold G Herman; Mark M Kockx
Cytosolic prostaglandin E2 synthase/p23 but not apoptosis-linked gene 2 is downregulated in human atherosclerotic plaques.
Cardiovascular research 2004;61(2):360-1.
2004: Wim Martinet; Mark M Kockx
Apoptosis in atheroclerosis: implications for plaque destabilization.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2004;66(1):61-79.
2003: Cheikh I Seye; Guido De Meyer; Wim Martinet; Michiel Knaapen; Hidde Bult; Arnold G Herman; Mark M Kockx
Upregulation and formation of SDS-resistant oligomers of the proapoptotic factor Bax in experimental atherosclerosis.
Annals of the New York Academy of Sciences 2003;1010():738-41.
2003: Wim Martinet; Dorien M Schrijvers; Guido De Meyer; Arnold G Herman; Mark M Kockx
Western array analysis of human atherosclerotic plaques: downregulation of apoptosis-linked gene 2.
Cardiovascular research 2003;60(2):259-67.
2003: Wim Martinet; Dorien M Schrijvers; Mark M Kockx
Nucleofection as an efficient nonviral transfection method for human monocytic cells.
Biotechnology letters 2003;25(13):1025-9.
2003: Guido De Meyer; Mark M Kockx; Michiel Knaapen; Wim Martinet; Dieter M M De Cleen; Hidde Bult; Arnold G Herman
Nitric oxide donor molsidomine favors features of atherosclerotic plaque stability during cholesterol lowering in rabbits.
Journal of cardiovascular pharmacology 2003;41(6):970-8.
2003: Wim Martinet; Michiel Knaapen; Guido De Meyer; Arnold G Herman; Mark M Kockx
Overexpression of the anti-apoptotic caspase-2 short isoform in macrophage-derived foam cells of human atherosclerotic plaques.
The American journal of pathology 2003;162(3):731-6.
2002: Wim Martinet; Dorien M Schrijvers; Guido De Meyer; Jeff Thielemans; Michiel Knaapen; Arnold G Herman; Mark M Kockx
Gene expression profiling of apoptosis-related genes in human atherosclerosis: upregulation of death-associated protein kinase.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(12):2023-9.
2002: Wim Martinet; Michiel Knaapen; Guido De Meyer; Arnold G Herman; Mark M Kockx
Elevated levels of oxidative DNA damage and DNA repair enzymes in human atherosclerotic plaques.
Circulation 2002;106(8):927-32.
2002: Guido De Meyer; Dieter M M De Cleen; Susan Cooper; Michiel Knaapen; Dominique M Jans; Wim Martinet; Arnold G Herman; Hidde Bult; Mark M Kockx
Platelet phagocytosis and processing of beta-amyloid precursor protein as a mechanism of macrophage activation in atherosclerosis.
Circulation research 2002;90(11):1197-204.
2001: Wim Martinet; Mark M Kockx
Apoptosis in atherosclerosis: focus on oxidized lipids and inflammation.
Current opinion in lipidology 2001;12(5):535-41.
2001: Michiel Knaapen; M J Davies; M De Bie; A J Haven; Wim Martinet; Mark M Kockx
Apoptotic versus autophagic cell death in heart failure.
Cardiovascular research 2001;51(2):304-12.
2001: Wim Martinet; Michiel Knaapen; Guido De Meyer; Arnold G Herman; Mark M Kockx
Oxidative DNA damage and repair in experimental atherosclerosis are reversed by dietary lipid lowering.
Circulation research 2001;88(7):733-9.