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Claudia Martini

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Costa Barbara; Pini Stefano; Gabelloni Pamela; Abelli Marianna; Lari Lisa; Cardini Alessandra; Muti Matteo; Gesi Camilla; Landi Stefano; Galderisi Silvana; Mucci Armida; Lucacchini Antonio; Cassano Giovanni B; Martini Claudia
Oxytocin receptor polymorphisms and adult attachment style in patients with depression.
Tuccinardi Tiziano; Taliani Sabrina; Bellandi Marusca; Da Settimo Federico; Da Pozzo Eleonora; Martini Claudia; Martinelli Adriano
A virtual screening study of the 18 kDa translocator protein using pharmacophore models combined with 3D-QSAR studies.
Pugliese Anna Maria; Trincavelli Maria Letizia; Lecca Davide; Coppi Elisabetta; Fumagalli Marta; Ferrario Silvia; Failli Paola; Daniele Simona; Martini Claudia; Pedata Felicita; Abbracchio Maria P
Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells.

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All Publications

2009: Costa Barbara; Pini Stefano; Gabelloni Pamela; Abelli Marianna; Lari Lisa; Cardini Alessandra; Muti Matteo; Gesi Camilla; Landi Stefano; Galderisi Silvana; Mucci Armida; Lucacchini Antonio; Cassano Giovanni B; Martini Claudia
Oxytocin receptor polymorphisms and adult attachment style in patients with depression.
Psychoneuroendocrinology 2009;34(10):1506-14.
2009: Tuccinardi Tiziano; Taliani Sabrina; Bellandi Marusca; Da Settimo Federico; Da Pozzo Eleonora; Martini Claudia; Martinelli Adriano
A virtual screening study of the 18 kDa translocator protein using pharmacophore models combined with 3D-QSAR studies.
ChemMedChem 2009;4(10):1686-94.
2009: Pugliese Anna Maria; Trincavelli Maria Letizia; Lecca Davide; Coppi Elisabetta; Fumagalli Marta; Ferrario Silvia; Failli Paola; Daniele Simona; Martini Claudia; Pedata Felicita; Abbracchio Maria P
Functional characterization of two isoforms of the P2Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells.
American journal of physiology. Cell physiology 2009;297(4):C1028-40.
2009: Guerrini Gabriella; Ciciani Giovanna; Cambi Giovanni; Bruni Fabrizio; Selleri Silvia; Guarino Chiara; Melani Fabrizio; Montali Marina; Martini Claudia; Ghelardini Carla; Norcini Monica; Costanzo Annarella
Synthesis, in vivo evaluation, and molecular modeling studies of new pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide derivatives. Identification of a bifunctional hydrogen bond area related to the inverse agonism.
Journal of medicinal chemistry 2009;52(15):4668-82.
2009: Costa Barbara; Pini Stefano; Martini Claudia; Abelli Marianna; Gabelloni Pamela; Ciampi Osele; Muti Matteo; Gesi Camilla; Lari Lisa; Cardini Alessandra; Mucci Armida; Bucci Paola; Lucacchini Antonio; Cassano Giovanni Battista
Mutation analysis of oxytocin gene in individuals with adult separation anxiety.
Psychiatry research 2009;168(2):87-93.
2009: Taliani Sabrina; Cosimelli Barbara; Da Settimo Federico; Marini Anna Maria; La Motta Concettina; Simorini Francesca; Salerno Silvia; Novellino Ettore; Greco Giovanni; Cosconati Sandro; Marinelli Luciana; Salvetti Francesca; L'Abbate Gianluca; Trasciatti Silvia; Montali Marina; Costa Barbara; Martini Claudia
Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor.
Journal of medicinal chemistry 2009;52(12):3723-34.
2009: Costa Barbara; Pini Stefano; Martini Claudia; Abelli Marianna; Gabelloni Pamela; Landi Stefano; Muti Matteo; Gesi Camilla; Lari Lisa; Cardini Alessandra; Galderisi Silvana; Mucci Armida; Lucacchini Antonio; Cassano Giovanni Battista
Ala147Thr substitution in translocator protein is associated with adult separation anxiety in patients with depression.
Psychiatric genetics 2009;19(2):110-1.
2009: Colotta Vittoria; Lenzi Ombretta; Catarzi Daniela; Varano Flavia; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Ciampi Osele; Pugliese Anna Maria; Traini Chiara; Pedata Felicita; Morizzo Erika; Moro Stefano
Pyrido[2,3-e]-1,2,4-triazolo[4,3-a]pyrazin-1-one as a new scaffold to develop potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2009;52(8):2407-19.
2009: Taliani S; Da Settimo F; Da Pozzo E; Chelli B; Martini C
Translocator protein ligands as promising therapeutic tools for anxiety disorders.
Current medicinal chemistry 2009;16(26):3359-80.
2008: Chelli Beatrice; Salvetti Alessandra; Da Pozzo Eleonora; Rechichi Mariarosa; Spinetti Francesca; Rossi Leonardo; Costa Barbara; Lena Annalisa; Rainaldi Giuseppe; Scatena Fabrizio; Vanacore Renato; Gremigni Vittorio; Martini Claudia
PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells.
Journal of cellular biochemistry 2008;105(3):712-23.
2008: Tonazzini I; Trincavelli M L; Montali M; Martini C
Regulation of A1 adenosine receptor functioning induced by P2Y1 purinergic receptor activation in human astroglial cells.
Journal of neuroscience research 2008;86(13):2857-66.
2008: Da Settimo Federico; Simorini Francesca; Taliani Sabrina; La Motta Concettina; Marini Anna Maria; Salerno Silvia; Bellandi Marusca; Novellino Ettore; Greco Giovanni; Cosimelli Barbara; Da Pozzo Eleonora; Costa Barbara; Simola Nicola; Morelli Micaela; Martini Claudia
Anxiolytic-like effects of N,N-dialkyl-2-phenylindol-3-ylglyoxylamides by modulation of translocator protein promoting neurosteroid biosynthesis.
Journal of medicinal chemistry 2008;51(18):5798-806.
2008: Trincavelli M L; Cuboni S; Montali M; Santaguida S; Lucacchini A; Martini C
Norepinephrine-mediated regulation of 5HT1 receptor functioning in human platelets.
Neurochemical research 2008;33(7):1292-300.
2008: Colotta Vittoria; Catarzi Daniela; Varano Flavia; Lenzi Ombretta; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Ciampi Osele; Traini Chiara; Pugliese Anna Maria; Pedata Felicita; Morizzo Erika; Moro Stefano
Synthesis, ligand-receptor modeling studies and pharmacological evaluation of novel 4-modified-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as potent and selective human A3 adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2008;16(11):6086-102.
2008: Tuccinardi Tiziano; Schenone Silvia; Bondavalli Francesco; Brullo Chiara; Bruno Olga; Mosti Luisa; Zizzari Alessandra Tania; Tintori Cristina; Manetti Fabrizio; Ciampi Osele; Trincavelli Maria Letizia; Martini Claudia; Martinelli Adriano; Botta Maurizio
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model.
ChemMedChem 2008;3(6):898-913.
2008: Trincavelli Maria Letizia; Tonazzini Ilaria; Montali Marina; Abbracchio Maria Pia; Martini Claudia
Short-term TNF-Alpha treatment induced A2B adenosine receptor desensitization in human astroglial cells.
Journal of cellular biochemistry 2008;104(1):150-61.
2008: Guerrini Gabriella; Ciciani Giovanna; Cambi Giovanni; Bruni Fabrizio; Selleri Silvia; Melani Fabrizio; Montali Marina; Martini Claudia; Ghelardini Carla; Norcini Monica; Costanzo Annarella
Novel 3-aroylpyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 8-substituted, ligands at GABAA/benzodiazepine receptor complex: synthesis, pharmacological and molecular modeling studies.
Bioorganic & medicinal chemistry 2008;16(8):4471-89.
2008: Chelli Beatrice; Pini Stefano; Abelli Marianna; Cardini Alessandra; Lari Lisa; Muti Matteo; Gesi Camilla; Cassano Giovanni B; Lucacchini Antonio; Martini Claudia
Platelet 18 kDa Translocator Protein density is reduced in depressed patients with adult separation anxiety.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2008;18(4):249-54.
2008: Cosimelli Barbara; Greco Giovanni; Ehlardo Marina; Novellino Ettore; Da Settimo Federico; Taliani Sabrina; La Motta Concettina; Bellandi Marusca; Tuccinardi Tiziano; Martinelli Adriano; Ciampi Osele; Trincavelli Maria Letizia; Martini Claudia
Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.
Journal of medicinal chemistry 2008;51(6):1764-70.
2008: Manetti Fabrizio; Brullo Chiara; Magnani Matteo; Mosci Francesca; Chelli Beatrice; Crespan Emmanuele; Schenone Silvia; Naldini Antonella; Bruno Olga; Trincavelli Maria Letizia; Maga Giovanni; Carraro Fabio; Martini Claudia; Bondavalli Francesco; Botta Maurizio
Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.
Journal of medicinal chemistry 2008;51(5):1252-9.
2008: Rechichi Mariarosa; Salvetti Alessandra; Chelli Beatrice; Costa Barbara; Da Pozzo Eleonora; Spinetti Francesca; Lena Annalisa; Evangelista Monica; Rainaldi Giuseppe; Martini Claudia; Gremigni Vittorio; Rossi Leonardo
TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells.
Biochimica et biophysica acta 2008;1782(2):118-25.
2008: Trincavelli Maria L; Melani Alessia; Guidi Sara; Cuboni Serena; Cipriani Sara; Pedata Felicita; Martini Claudia
Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain.
Journal of neurochemistry 2008;104(2):479-90.
2008: Piccinni Armando; Marazziti Donatella; Catena Mario; Domenici Luciano; Del Debbio Alessandro; Bianchi Carolina; Mannari Claudio; Martini Claudia; Da Pozzo Eleonora; Schiavi Elisa; Mariotti Alessandra; Roncaglia Isabella; Palla Agnese; Consoli Giorgio; Giovannini Luca; Massimetti Gabriele; Dell'Osso Liliana
Plasma and serum brain-derived neurotrophic factor (BDNF) in depressed patients during 1 year of antidepressant treatments.
Journal of affective disorders 2008;105(1-3):279-83.
2008: Lecca Davide; Trincavelli Maria Letizia; Gelosa Paolo; Sironi Luigi; Ciana Paolo; Fumagalli Marta; Villa Giovanni; Verderio Claudia; Grumelli Carlotta; Guerrini Uliano; Tremoli Elena; Rosa Patrizia; Cuboni Serena; Martini Claudia; Buffo Annalisa; Cimino Mauro; Abbracchio Maria P
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair.
PloS one 2008;3(10):e3579.
2007: Giannaccini Gino; Betti Laura; Pirone Andrea; Palego Lionella; Fabiani Ortenzio; Fabbrini Laura; Mascia Giovanni; Giusti Laura; Macchia Marco; Giusiani Mario; Martini Claudia; Lucacchini Antonio
Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.
Neurochemistry international 2007;51(8):496-506.
2007: Da Settimo Federico; Primofiore Giampaolo; Taliani Sabrina; Marini Anna Maria; La Motta Concettina; Simorini Francesca; Salerno Silvia; Sergianni Valentina; Tuccinardi Tiziano; Martinelli Adriano; Cosimelli Barbara; Greco Giovanni; Novellino Ettore; Ciampi Osele; Trincavelli Maria Letizia; Martini Claudia
5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.
Journal of medicinal chemistry 2007;50(23):5676-84.
2007: Tonazzini I; Trincavelli M L; Storm-Mathisen J; Martini C; Bergersen L H
Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus.
The European journal of neuroscience 2007;26(4):890-902.
2007: Colotta Vittoria; Catarzi Daniela; Varano Flavia; Capelli Francesca; Lenzi Ombretta; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Ciampi Osele; Pugliese Anna Maria; Pedata Felicita; Schiesaro Andrea; Morizzo Erika; Moro Stefano
New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2007;50(17):4061-74.
2007: Primofiore Giampaolo; Taliani Sabrina; Da Settimo Federico; Marini Anna Maria; La Motta Concettina; Simorini Francesca; Patrizi Maria Paola; Sergianni Valentina; Novellino Ettore; Greco Giovanni; Cosimelli Barbara; Calderone Vincenzo; Montali Marina; Besnard François; Martini Claudia
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
Journal of medicinal chemistry 2007;50(7):1627-34.
2007: Guerrini Gabriella; Ciciani Giovanna; Cambi Giovanni; Bruni Fabrizio; Selleri Silvia; Besnard François; Montali Marina; Martini Claudia; Ghelardini Carla; Galeotti Nicoletta; Costanzo Annarella
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.
Bioorganic & medicinal chemistry 2007;15(7):2573-86.
2007: Taliani Sabrina; Simorini Francesca; Sergianni Valentina; La Motta Concettina; Da Settimo Federico; Cosimelli Barbara; Abignente Enrico; Greco Giovanni; Novellino Ettore; Rossi Leonardo; Gremigni Vittorio; Spinetti Francesca; Chelli Beatrice; Martini Claudia
New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation.
Journal of medicinal chemistry 2007;50(2):404-7.
2007: Da Settimo F; Taliani S; Trincavelli M L; Montali M; Martini C
GABA A/Bz receptor subtypes as targets for selective drugs.
Current medicinal chemistry 2007;14(25):2680-701.
2006: Ciana Paolo; Fumagalli Marta; Trincavelli Maria Letizia; Verderio Claudia; Rosa Patrizia; Lecca Davide; Ferrario Silvia; Parravicini Chiara; Capra Valérie; Gelosa Paolo; Guerrini Uliano; Belcredito Silvia; Cimino Mauro; Sironi Luigi; Tremoli Elena; Rovati G Enrico; Martini Claudia; Abbracchio Maria P
The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.
The EMBO journal 2006;25(19):4615-27.
2006: Lenzi Ombretta; Colotta Vittoria; Catarzi Daniela; Varano Flavia; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Ciampi Osele; Varani Katia; Marighetti Federico; Morizzo Erika; Moro Stefano
4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2006;49(13):3916-25.
2006: Primofiore Giampaolo; Da Settimo Federico; Marini Anna Maria; Taliani Sabrina; La Motta Concettina; Simorini Francesca; Novellino Ettore; Greco Giovanni; Cosimelli Barbara; Ehlardo Marina; Sala Annalisa; Besnard François; Montali Marina; Martini Claudia
Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.
Journal of medicinal chemistry 2006;49(8):2489-95.
2006: Martini Claudia; Tuscano Daniela; Trincavelli Maria Letizia; Cerrai Elisa; Bianchi Maria; Ciapparelli Antonio; Alessio Lucioni; Novelli Letizia; Catena Mario; Lucacchini Antonio; Cassano Giovanni Battista; Dell'Osso Liliana
Upregulation of A2A adenosine receptors in platelets from patients affected by bipolar disorders under treatment with typical antipsychotics.
Journal of psychiatric research 2006;40(1):81-8.
2006: Guerrini Gabriella; Costanzo Annarella; Ciciani Giovanna; Bruni Fabrizio; Selleri Silvia; Costagli Camilla; Besnard François; Costa Barbara; Martini Claudia; De Siena Gaetano; Malmberg-Aiello Petra
Benzodiazepine receptor ligands. 8: synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: high affinity ligands endowed with inverse-agonist pharmacological efficacy.
Bioorganic & medicinal chemistry 2006;14(3):758-75.
2006: Costa Barbara; Salvetti Alessandra; Rossi Leonardo; Spinetti Francesca; Lena Annalisa; Chelli Beatrice; Rechichi Mariarosa; Da Pozzo Eleonora; Gremigni Vittorio; Martini Claudia
Peripheral benzodiazepine receptor: characterization in human T-lymphoma Jurkat cells.
Molecular pharmacology 2006;69(1):37-44.
2005: Novellino Ettore; Cosimelli Barbara; Ehlardo Marina; Greco Giovanni; Iadanza Manuela; Lavecchia Antonio; Rimoli Maria Grazia; Sala Annalisa; Da Settimo Antonio; Primofiore Giampaolo; Da Settimo Federico; Taliani Sabrina; La Motta Concettina; Klotz Karl-Norbert; Tuscano Daniela; Trincavelli Maria Letizia; Martini Claudia
2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.
Journal of medicinal chemistry 2005;48(26):8253-60.
2005: Catarzi Daniela; Colotta Vittoria; Varano Flavia; Lenzi Ombretta; Filacchioni Guido; Trincavelli Letizia; Martini Claudia; Montopoli Christian; Moro Stefano
1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.
Journal of medicinal chemistry 2005;48(25):7932-45.
2005: Manetti Fabrizio; Schenone Silvia; Bondavalli Francesco; Brullo Chiara; Bruno Olga; Ranise Angelo; Mosti Luisa; Menozzi Giulia; Fossa Paola; Trincavelli Maria Letizia; Martini Claudia; Martinelli Adriano; Tintori Cristina; Botta Maurizio
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.
Journal of medicinal chemistry 2005;48(23):7172-85.
2005: Selleri Silvia; Bruni Fabrizio; Costagli Camilla; Costanzo Annarella; Guerrini Gabriella; Ciciani Giovanna; Gratteri Paola; Besnard François; Costa Barbara; Montali Marina; Martini Claudia; Fohlin Jonna; De Siena Gaetano; Aiello Petra Malmberg
A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents.
Journal of medicinal chemistry 2005;48(21):6756-60.
2005: Amadio Susanna; D'Ambrosi Nadia; Trincavelli Maria Letizia; Tuscano Daniela; Sancesario Giuseppe; Bernadi Giorgio; Martini Claudia; Volonté Cinzia
Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons.
Neurochemistry international 2005;47(5):334-42.
2005: Pini Stefano; Martini Claudia; Abelli Marianna; Muti Matteo; Gesi Camilla; Montali Marina; Chelli Beatrice; Lucacchini Antonio; Cassano Giovanni B
Peripheral-type benzodiazepine receptor binding sites in platelets of patients with panic disorder associated to separation anxiety symptoms.
Psychopharmacology 2005;181(2):407-11.
2005: Da Settimo Federico; Primofiore Giampaolo; La Motta Concettina; Taliani Sabrina; Simorini Francesca; Marini Anna Maria; Mugnaini Laura; Lavecchia Antonio; Novellino Ettore; Tuscano Daniela; Martini Claudia
Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.
Journal of medicinal chemistry 2005;48(16):5162-74.
2005: Abelli Marianna; Martini Claudia; Pini Stefano; Gesi Camilla; Cassano Giovanni B
The role of newer antiglutamatergic agents as mood-stabilizers in bipolar disorder.
Current drug targets 2005;6(5):607-14.
2005: Selleri Silvia; Gratteri Paola; Costagli Camilla; Bonaccini Claudia; Costanzo Annarella; Melani Fabrizio; Guerrini Gabriella; Ciciani Giovanna; Costa Barbara; Spinetti Francesca; Martini Claudia; Bruni Fabrizio
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation.
Bioorganic & medicinal chemistry 2005;13(16):4821-34.
2005: Fossa Paola; Pestarino Marco; Menozzi Giulia; Mosti Luisa; Schenone Silvia; Ranise Angelo; Bondavalli Francesco; Trincavelli M Letizia; Lucacchini Antonio; Martini Claudia
New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies.
Organic & biomolecular chemistry 2005;3(12):2262-70.
2005: Chelli Beatrice; Rossi Leonardo; Da Pozzo Eleonora; Costa Barbara; Spinetti Francesca; Rechichi Mariarosa; Salvetti Alessandra; Lena Annalisa; Simorini Francesca; Vanacore Renato; Scatena Fabrizio; Da Settimo Federico; Gremigni Vittorio; Martini Claudia
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells.
Chembiochem : a European journal of chemical biology 2005;6(6):1082-8.
2005: Primofiore Giampaolo; Da Settimo Federico; Taliani Sabrina; Salerno Silvia; Novellino Ettore; Greco Giovanni; Cosimelli Barbara; Besnard François; Costa Barbara; Montali Marina; Martini Claudia
High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives.
Journal of medicinal chemistry 2005;48(8):2936-43.
2005: Primofiore Giampaolo; Da Settimo Federico; Marini Anna Maria; Simorini Francesca; La Motta Concettina; Taliani Sabrina; Laneri Sonia; Trincavelli Letizia; Martini Claudia
Synthesis and benzodiazepine receptor affinity of derivatives of the new tricyclic heteroaromatic system pyrido[3',2':5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one.
Archiv der Pharmazie 2005;338(2-3):126-32.
2005: Catarzi Daniela; Colotta Vittoria; Varano Flavia; Calabri Francesca Romana; Lenzi Ombretta; Filacchioni Guido; Trincavelli Letizia; Martini Claudia; Tralli Andrea; Montopoli Christian; Moro Stefano
2-aryl-8-chloro-1,2,4-triazolo[1,5-a]quinoxalin-4-amines as highly potent A1 and A3 adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2005;13(3):705-15.
2005: Bazzichi Laura; Trincavelli Letizia; Rossi Alessandra; De Feo Francesca; Lucacchini Antonio; Bombardieri Stefano; Martini Claudia
A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.
Arthritis research & therapy 2005;7(2):R189-95.
2004: Trincavelli Maria L; Marroni Matteo; Tuscano Daniela; Ceruti Stefania; Mazzola Alessia; Mitro Nico; Abbracchio Maria P; Martini Claudia
Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells.
Journal of neurochemistry 2004;91(5):1180-90.
2004: Marselli Lorella; Trincavelli Letizia; Santangelo Carmela; Lupi Roberto; Del Guerra Silvia; Boggi Ugo; Falleni Alessandra; Gremigni Vittorio; Mosca Franco; Martini Claudia; Dotta Francesco; Di Mario Umberto; Del Prato Stefano; Marchetti Piero
The role of peripheral benzodiazepine receptors on the function and survival of isolated human pancreatic islets.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(2):207-14.
2004: Colotta Vittoria; Catarzi Daniela; Varano Flavia; Calabri Francesca Romana; Lenzi Ombretta; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Deflorian Francesca; Moro Stefano
1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.
Journal of medicinal chemistry 2004;47(14):3580-90.
2004: Chelli Beatrice; Lena Annalisa; Vanacore Renato; Da Pozzo Eleonora; Costa Barbara; Rossi Leonardo; Salvetti Alessandra; Scatena Fabrizio; Ceruti Stefania; Abbracchio Maria P; Gremigni Vittorio; Martini Claudia
Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells.
Biochemical pharmacology 2004;68(1):125-34.
2004: Fumagalli Marta; Trincavelli Letizia; Lecca Davide; Martini Claudia; Ciana Paolo; Abbracchio Maria P
Cloning, pharmacological characterisation and distribution of the rat G-protein-coupled P2Y(13) receptor.
Biochemical pharmacology 2004;68(1):113-24.
2004: Martini Claudia; Trincavelli Maria Letizia; Tuscano Daniela; Carmassi Claudia; Ciapparelli Antonio; Lucacchini Antonio; Cassano Giovanni Battista; Dell'Osso Liliana
Serotonin-mediated phosphorylation of extracellular regulated kinases in platelets of patients with panic disorder versus controls.
Neurochemistry international 2004;44(8):627-39.
2004: Primofiore Giampaolo; Da Settimo Federico; Taliani Sabrina; Simorini Francesca; Patrizi Maria Paola; Novellino Ettore; Greco Giovanni; Abignente Enrico; Costa Barbara; Chelli Beatrice; Martini Claudia
N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor.
Journal of medicinal chemistry 2004;47(7):1852-5.
2004: Schenone Silvia; Bruno Olga; Bondavalli Francesco; Ranise Angelo; Mosti Luisa; Menozzi Giulia; Fossa Paola; Manetti Fabrizio; Morbidelli Lucia; Trincavelli Letizia; Martini Claudia; Lucacchini Antonio
Synthesis of 1-(2-chloro-2-phenylethyl)-6-methylthio-1H-pyrazolo[3,4-d]pyrimidines 4-amino substituted and their biological evaluation.
European journal of medicinal chemistry 2004;39(2):153-60.
2004: Colotta Vittoria; Catarzi Daniela; Varano Flavia; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Lucacchini Antonio; Colotta Vittoria
Synthesis and structure-activity relationships of 4-cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one derivatives as A1 and A3 adenosine receptor antagonists.
Archiv der Pharmazie 2004;337(1):35-41.
2004: Dell'Osso Liliana; Carmassi Claudia; Palego Lionella; Trincavelli Maria Letizia; Tuscano Daniela; Montali Marina; Sbrana Simone; Ciapparelli Antonio; Lucacchini Antonio; Cassano Giovanni Battista; Martini Claudia
Serotonin-mediated cyclic AMP inhibitory pathway in platelets of patients affected by panic disorder.
Neuropsychobiology 2004;50(1):28-36.
2003: Trincavelli Maria L; Falleni Alessandra; Chelli Beatrice; Tuscano Daniela; Costa Barbara; Gremigni Vittorio; Lucacchini Antonio; Martini Claudia
A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis.
Biochemical pharmacology 2003;66(10):1953-62.
2003: Primofiore Giampaolo; Da Settimo Federico; Taliani Sabrina; Marini Anna Maria; Simorini Francesca; Novellino Ettore; Greco Giovanni; Trincavelli Letizia; Martini Claudia
Geometrically constrained analogues of N-benzylindolylglyoxylylamides: [1, 2, 4]triazino[4, 3-a]benzimidazol-4(10H)-one derivatives as potential new ligands at the benzodiazepine receptor.
Archiv der Pharmazie 2003;336(9):413-21.
2003: Colotta Vittoria; Catarzi Daniela; Varano Flavia; Filacchioni Guido; Martini Claudia; Trincavelli Letizia; Lucacchini Antonio
Synthesis and structure-activity relationships of a new set of 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives as adenosine receptor antagonists.
Bioorganic & medicinal chemistry 2003;11(16):3541-50.
2003: Selleri Silvia; Bruni Fabrizio; Costagli Camilla; Costanzo Annarella; Guerrini Gabriella; Ciciani Giovanna; Gratteri Paola; Bonaccini Claudia; Malmberg Aiello Petra; Besnard François; Renard Stephane; Costa Barbara; Martini Claudia
Synthesis and benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. 3. New 6-(3-thienyl) series as alpha 1 selective ligands.
Journal of medicinal chemistry 2003;46(2):310-3.
2002: Martini Claudia; Chelli Beatrice; Betti Laura; Montali Marina; Mancuso Michelangelo; Giannaccini Gino; Rocchi Anna; Murri Luigi; Siciliano Gabriele
Peripheral benzodiazepine binding sites in platelets of patients affected by mitochondrial diseases and large scale mitochondrial DNA rearrangements.
Molecular medicine (Cambridge, Mass.) 2002;8(12):841-6.
2002: Costanzo Annarella; Guerrini Gabriella; Ciciani Giovanna; Bruni Fabrizio; Costagli Camilla; Selleri Silvia; Besnard François; Costa Barbara; Martini Claudia; Malmberg-Aiello Petra
Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents.
Journal of medicinal chemistry 2002;45(26):5710-20.
2002: Trincavelli M L; Tuscano D; Marroni M; Falleni A; Gremigni V; Ceruti S; Abbracchio M P; Jacobson K A; Cattabeni F; Martini C
A3 adenosine receptors in human astrocytoma cells: agonist-mediated desensitization, internalization, and down-regulation.
Molecular pharmacology 2002;62(6):1373-84.
2002: Novellino Ettore; Abignente Enrico; Cosimelli Barbara; Greco Giovanni; Iadanza Manuela; Laneri Sonia; Lavecchia Antonio; Rimoli Maria Grazia; Settimo Federico Da; Primofiore Giampaolo; Tuscano Daniela; Trincavelli Letizia; Martini Claudia
Design, synthesis and biological evaluation of novel N-alkyl- and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs) as novel A(1) adenosine receptor antagonists.
Journal of medicinal chemistry 2002;45(23):5030-6.
2002: Macchia Marco; Bertini Simone; Di Bussolo Valeria; Manera Clementina; Martini Claudia; Minutolo Filippo; Mori Claudio; Saccomanni Giuseppe; Tuscano Daniela; Ferrarini Pier Luigi
4-[6-(Dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor.
Farmaco (Società chimica italiana : 1989) 2002;57(10):783-6.
2002: Bondavalli Francesco; Botta Maurizio; Bruno Olga; Ciacci Andrea; Corelli Federico; Fossa Paola; Lucacchini Antonio; Manetti Fabrizio; Martini Claudia; Menozzi Giulia; Mosti Luisa; Ranise Angelo; Schenone Silvia; Tafi Andrea; Trincavellic Maria Letizia
Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.
Journal of medicinal chemistry 2002;45(22):4875-87.
2002: Trincavelli M Letizia; Tuscano Daniela; Marroni Matteo; Klotz Karl-Norbert; Lucacchini Antonio; Martini Claudia
Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation.
Biochimica et biophysica acta 2002;1591(1-3):55-62.
2002: Trincavelli Maria L; Costa Barbara; Tuscano Daniela; Lucacchini Antonio; Martini Claudia
Up-regulation of A(2A) adenosine receptors by proinflammatory cytokines in rat PC12 cells.
Biochemical pharmacology 2002;64(4):625-31.
2002: Macchia Bruno; Manera Clementina; Martinelli Adriano; Nencetti Susanna; Orlandini Elisabetta; Breschi Maria Cristina; Martini Claudia; Martinotti Enrica
Spirotetrahydronaphthalene analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1 (2H)-3'-piperidines].
The Journal of pharmacy and pharmacology 2002;54(5):649-60.
2002: Salvetti Francesca; Cecchetti Paolo; Janigro Damir; Lucacchini Antonio; Benzi Luca; Martini Claudia
Insulin permeability across an in vitro dynamic model of endothelium.
Pharmaceutical research 2002;19(4):445-50.
2002: Palego Lionella; Biondi Luciano; Giannaccini Gino; Sarno Nannina; Elmi Simona; Ciapparelli Antonio; Cassano Giovanni Battista; Lucacchini Antonio; Martini Claudia; Dell'Osso Liliana
Clozapine, norclozapine plasma levels, their sum and ratio in 50 psychotic patients: influence of patient-related variables.
Progress in neuro-psychopharmacology & biological psychiatry 2002;26(3):473-80.
2002: Trincavelli M Letizia; Marselli Lorella; Falleni Alessandra; Gremigni Vittorio; Ragge Esther; Dotta Francesco; Santangelo Carmela; Marchetti Piero; Lucacchini Antonio; Martini Claudia
Upregulation of mitochondrial peripheral benzodiazepine receptor expression by cytokine-induced damage of human pancreatic islets.
Journal of cellular biochemistry 2002;84(3):636-44.
2001: Macchia M; Salvetti F; Bertini S; Di Bussolo V; Gattuso L; Gesi M; Hamdan M; Klotz K N; Laragione T; Lucacchini A; Minutolo F; Nencetti S; Papi C; Tuscano D; Martini C
7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors.
Bioorganic & medicinal chemistry letters 2001;11(23):3023-6.
2001: Selleri S; Bruni F; Costagli C; Costanzo A; Guerrini G; Ciciani G; Costa B; Martini C
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands.
Bioorganic & medicinal chemistry 2001;9(10):2661-71.
2001: Schenone S; Bruno O; Fossa P; Ranise A; Menozzi G; Mosti L; Bondavalli F; Martini C; Trincavelli L
Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands.
Bioorganic & medicinal chemistry letters 2001;11(18):2529-31.
2001: Primofiore G; Settimo F D; Taliani S; Marini A M; Novellino E; Greco G; Lavecchia A; Besnard F; Trincavelli L; Costa B; Martini C
Novel N-(arylalkyl)indol-3-ylglyoxylylamides targeted as ligands of the benzodiazepine receptor: synthesis, biological evaluation, and molecular modeling analysis of the structure-activity relationships.
Journal of medicinal chemistry 2001;44(14):2286-97.
2001: Abbracchio M P; Camurri A; Ceruti S; Cattabeni F; Falzano L; Giammarioli A M; Jacobson K A; Trincavelli L; Martini C; Malorni W; Fiorentini C
The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins.
Annals of the New York Academy of Sciences 2001;939():63-73.
2001: Chelli B; Falleni A; Salvetti F; Gremigni V; Lucacchini A; Martini C
Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue.
Biochemical pharmacology 2001;61(6):695-705.
2001: Da Settimo F; Primofiore G; Taliani S; Marini A M; La Motta C; Novellino E; Greco G; Lavecchia A; Trincavelli L; Martini C
3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.
Journal of medicinal chemistry 2001;44(3):316-27.
2000: Trincavelli M L; Tuscano D; Cecchetti P; Falleni A; Benzi L; Klotz K N; Gremigni V; Cattabeni F; Lucacchini A; Martini C
Agonist-induced internalization and recycling of the human A(3) adenosine receptors: role in receptor desensitization and resensitization.
Journal of neurochemistry 2000;75(4):1493-501.
2000: Colotta V; Catarzi D; Varano F; Cecchi L; Filacchioni G; Martini C; Trincavelli L; Lucacchini A
Synthesis and structure-activity relationships of a new set of 2-arylpyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists.
Journal of medicinal chemistry 2000;43(16):3118-24.
2000: Gesi M; Pellegrini A; Lenzi P; Da Settimo F; Martini C; Salvetti F; Taliani S; Fornai F
Effects of newly-developed benzodiazepine ligands on noise-induced mitochondrial damage in the rat.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2000;182(4):311-8.
2000: Colotta V; Catarzi D; Varano F; Cecchi L; Filacchioni G; Martini C; Trincavelli L; Lucacchini A
1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists.
Journal of medicinal chemistry 2000;43(6):1158-64.
2000: Salvetti F; Chelli B; Gesi M; Pellegrini A; Giannaccini G; Lucacchini A; Martini C
Effect of noise exposure on rat cardiac peripheral benzodiazepine receptors.
Life sciences 2000;66(13):1165-75.
2000: Giannaccini G; Betti L; Martini C; Bistocchi M; Mascia G; Piccolino M; Lucacchini A
Autoradiographic distribution of peripheral benzodiazepine receptors in the retina of the albino rabbit, Lepus cunicula.
Neuroscience letters 2000;280(1):37-40.
2000: Primofiore G; Da Settimo F; Taliani S; Marini A M; La Motta C; Novellino E; Greco G; Gesi M; Trincavelli L; Martini C
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands.
Journal of medicinal chemistry 2000;43(1):96-102.
1999: Selleri S; Bruni F; Costagli C; Costanzo A; Guerrini G; Ciciani G; Costa B; Martini C
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. Part 1: study of the structural features for BZR recognition.
Bioorganic & medicinal chemistry 1999;7(12):2705-11.
1999: Falleni A; Trincavelli M L; Macchia M; Salvetti F; Hamdan M; Calvani F; Gremigni V; Lucacchini A; Martini C
A(1) adenosine receptors in human neutrophils: direct binding and electron microscope visualization.
Journal of cellular biochemistry 1999;75(2):235-44.
1999: Guerrini G; Costanzo A; Bruni F; Ciciani G; Selleri S; Gratteri P; Costa B; Martini C; Lucacchini A
Benzodiazepine receptor ligands. III. Synthesis and biological evaluation of 2- and/or 3-substituted pyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides.
Farmaco (Società chimica italiana : 1989) 1999;54(6):375-89.
1999: Costanzo A; Guerrini G; Ciciani G; Bruni F; Selleri S; Costa B; Martini C; Lucacchini A; Aiello P M; Ipponi A
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides.
Journal of medicinal chemistry 1999;42(12):2218-26.
1999: Colotta V; Catarzi D; Varano F; Cecchi L; Filacchioni G; Martini C; Trincavelli L; Lucacchini A
4-Amino-6-benzylamino-1,2-dihydro-2-phenyl-1,2,4-triazolo [4,3-alpha]-quinoxalin-1-one: a new A2A adenosine receptor antagonist with high selectivity versus A1 receptors.
Archiv der Pharmazie 1999;332(2):39-41.
1998: Macchia M; Salvetti F; Barontini S; Calvani F; Gesi M; Hamdan M; Lucacchini A; Pellegrini A; Soldani P; Martini C
Fluorescent probes for adenosine receptors: synthesis and biology of N6-dansylaminoalkyl-substituted NECA derivatives.
Bioorganic & medicinal chemistry letters 1998;8(22):3223-8.
1998: Giannaccini G; Lupi R; Trincavelli M L; Navalesi R; Betti L; Marchetti P; Lucacchini A; Del Guerra S; Martini C
Characterization of sulfonylurea receptors in isolated human pancreatic islets.
Journal of cellular biochemistry 1998;71(2):182-8.
1998: Da Settimo A; Primofiore G; Da Settimo F; Marini A M; Novellino E; Greco G; Gesi M; Martini C; Giannaccini G; Lucacchini A
N'-Phenylindol-3-ylglyoxylohydrazide derivatives: synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors.
Journal of medicinal chemistry 1998;41(20):3821-30.
1998: Bertelli L; Biagi G; Giorgi I; Livi O; Manera C; Scartoni V; Martini C; Giannaccini G; Trincavelli L; Barili P L
1,2,3-Triazolo[1,5-a][1,4]- and 1,2,3-triazolo[1,5-a]-[1,5]benzodiazepine derivatives: synthesis and benzodiazepine receptor binding.
Farmaco (Società chimica italiana : 1989) 1998;53(4):305-11.
1998: Costa B; Giusti L; Martini C; Lucacchini A
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5'-phosphate.
Neurochemistry international 1998;32(4):361-4.
1998: Colotta V; Catarzi D; Varano F; Melani F; Filacchioni G; Cecchi L; Trincavelli L; Martini C; Lucacchini A
Synthesis and A1 and A2A adenosine binding activity of some pyrano[2,3-c]pyrazol-4-ones.
Farmaco (Società chimica italiana : 1989) 1998;53(3):189-96.
1998: Martini C; Trincavelli L; Fiorini M; Salvetti F; Montali U; Falleni A; Gremigni V; Lucacchini A
A1 adenosine receptors in human neutrophils. Electron microscope localization.
Advances in experimental medicine and biology 1998;431():107-11.
1998: Martini C; Trincavelli L; Fiorini M; Nardi M; Bazzichi L; Lucacchini A
Effect of FMLP stimulation on [3H]-NECA binding to adenosine receptors in neutrophils membranes.
Advances in experimental medicine and biology 1998;431():89-94.
1997: Da Settimo A; Primofiore G; Marini A M; Da Settimo F; Nuti V; Martini C; Trincavelli L; Lucacchini A
Isosteric replacement of amide by ester function. Synthesis and benzodiazepine receptor affinity of indol-3-ylglyoxylyl ester derivatives.
Farmaco (Società chimica italiana : 1989) 1997;52(6-7):421-8.
1997: Martini C; Trincavelli L; Lucacchini A
Chemical modifications of striatal A2A adenosine receptors: a possible role for tyrosine at the ligand binding sites.
Biochimica et biophysica acta 1997;1326(1):67-74.
1997: Giusti L; Marchetti P; Trincavelli L; Lupi R; Martini C; Lucacchini A; Del Guerra S; Tellini C; Carmellini M; Navalesi R
Peripheral benzodiazepine receptors in isolated human pancreatic islets.
Journal of cellular biochemistry 1997;64(2):273-7.
1996: Costa B; Giusti L; Martini C; Lucacchini A
2,3-Butanedione inactivates the [3H]nitrendipine binding sites, whereas diethylpyrocarbonate does not.
Neurochemistry international 1996;29(6):623-7.
1996: Da Settimo A; Primofiore G; Da Settimo F; Marini A M; Novellino E; Greco G; Martini C; Giannaccini G; Lucacchini A
Synthesis, structure-activity relationships, and molecular modeling studies of N-(indol-3-ylglyoxylyl)benzylamine derivatives acting at the benzodiazepine receptor.
Journal of medicinal chemistry 1996;39(26):5083-91.
1996: Chiellini G; Giannaccini G; Martini C; Lucacchini A
Binding of beta 1-adrenoceptor antagonist [3H]CGP 26505 in rat cerebral cortex and sinus atrial node.
Neurochemical research 1996;21(10):1149-53.
1996: Marchetti P; Trincavelli L; Giannarelli R; Giusti L; Coppelli A; Martini C; Navalesi R; Lucacchini A
Characterization of peripheral benzodiazepine receptors in purified large mammal pancreatic islets.
Biochemical pharmacology 1996;51(11):1437-42.
1996: Costa B; Giusti L; Martini C; Lucacchini A
Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain.
Neurochemical research 1996;21(5):537-40.
1996: Grandolini G; Ambrogi V; Perioli L; Giannaccini G; Lucacchini A; Martini C
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. X--Synthesis and inhibition of benzodiazepine receptor binding of new 1,4-thiazine and 1,5-thiazepine polycondensed heterocycles with steroidal structure.
Farmaco (Società chimica italiana : 1989) 1996;51(3):203-7.
1996: Da Settimo A; Primofiore G; Da Settimo F; Novellino E; Greco G; Martini C; Senatore G; Lucacehini A
Indole derivatives as probes to study the benzodiazepine binding site in GABA receptor complex.
Advances in experimental medicine and biology 1996;398():677-83.
1996: Marazziti D; Giannaccini G; Martini C; Simoncini M; Dell'Osso L; Lucacchini A; Cassano G B
Benzodiazepine binding inhibitory activity: new supportive findings on its presence in psychiatric patients and further biochemical analyses.
Neuropsychobiology 1996;34(1):9-13.
1995: Selleri S; Bruni F; Costanzo A; Guerrini G; Casilli M L; Giusti L; Lucacchini A; Martini C
New 2,3-substituted 4,7-dihydro-6-(1'H-pyrazol-3'-yl)pyrazolo[1,5-a] pyrimidin-7-ones and related compounds: synthesis and benzodiazepine receptor binding study.
Farmaco (Società chimica italiana : 1989) 1995;50(10):679-87.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Breschi C; Martini C; Scatizzi R
N(6) or N(9) substituted 2-phenyl-8-azaadenines: affinity for A1 adenosine receptors. VII.
Farmaco (Società chimica italiana : 1989) 1995;50(10):659-67.
1995: Catarzi D; Cecchi L; Colotta V; Filacchioni G; Varano F; Martini C; Giousti L; Lucacchini A
Synthesis of some 2-aryl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-ones as tools to define the essential pharmacophoric descriptors of a benzodiazepine receptor ligand.
Journal of medicinal chemistry 1995;38(12):2196-201.
1995: Da Settimo A; Primofiore G; Da Settimo F; Marini A M; Novellino E; Greco G; Martini C; Senatore G; Lucacchini A
Synthesis of 3-(2'-furoyl)indole derivatives as potential new ligands at the benzodiazepine receptor, structurally more restrained analogues of indoleglyoxylylamides.
Farmaco (Società chimica italiana : 1989) 1995;50(5):311-20.
1995: Catarzi D; Cecchi L; Colotta V; Filacchioni G; Martini C; Tacchi P; Lucacchini A
Tricyclic heteroaromatic systems. Synthesis and A1 and A2a adenosine binding activities of some 1-aryl-1,4-dihydro-3-methyl[1]benzopyrano[2,3-c] pyrazol-4-ones, 1-aryl-4,9-dihydro-3-methyl-1H-pyrazolo[3,4-b]quinolin-4- ones, and 1-aryl-1H-imidazo[4,5-b]quinoxalines.
Journal of medicinal chemistry 1995;38(8):1330-6.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Velo S; Martini C; Senatore G; Barili P L
1,2,3-triazole[4,5-d]pyridazines--IV. Preparation and adenosine receptor binding of new 4 and/or 7 aminoderivatives.
Farmaco (Società chimica italiana : 1989) 1995;50(2):99-105.
1995: Primofiore G; Da Settimo F; Marini A M; La Motta C; Martini C; Senatore G; Lucacchini A
N-(indol-3-ylglyoxylyl)amino acid ester derivatives. Synthesis and interaction properties at the benzodiazepine receptor.
Farmaco (Società chimica italiana : 1989) 1995;50(1):5-12.
1995: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
Synthesis of new N(6)-substituted 2-phenyl-8-azaadenosines. Their affinity for adenosine A1 and A2 receptors. A comparison with the corresponding 2-phenyl-9-benzyl-8-azaadenines. VI.
Farmaco (Società chimica italiana : 1989) 1995;50(1):13-9.
1995: Breschi M C; Martini C; Scatizzi R; Cristofani R; Giannaccini G; Martinotti E; Lucacchini A
Benzodiazepine agonists reverse the effects of noise exposure on central benzodiazepine receptors and cardiac responsiveness.
Life sciences 1995;57(11):1131-40.
1994: Rotondo A; Giannaccini G; Quattrone C; Marazziti D; Martini C; Cassano G B; Lucacchini A
Solubilization and characterization of [3H]imipramine and [3H]paroxetine binding sites from calf striatum.
Neurochemical research 1994;19(10):1295-300.
1994: Catarzi D; Cecchi L; Colotta V; Melani F; Filacchioni G; Martini C; Giusti L; Lucacchini A
Structure-activity relationships of 1,2,4-triazolo[1,5-a] quinoxalines and their 1-deaza analogues imidazo[1,2-a]quinoxalines at the benzodiazepine receptor.
Journal of medicinal chemistry 1994;37(18):2846-50.
1994: Giusti L; Trincavelli L; Martini C; Lucacchini A
Characterization of peripheral-type benzodiazepine binding sites from rat and pig pancreas.
Biochemical pharmacology 1994;48(3):583-6.
1994: Da Settimo A; Primofiore G; Da Settimo F; Simorini F; Barili P L; Senatore G; Martini C; Lucacchini A
Synthesis and benzodiazepine receptor activity of some 4,5-dihydro-1H-pyrazolo[4,3-c][1,8]naphthyridine derivatives.
Drug design and discovery 1994;11(4):307-28.
1994: Macchia B; Balsamo A; Breschi M C; Chiellini G; Macchia M; Martinelli A; Martini C; Nardini C; Nencetti S; Rossello A
The [(methyloxy)imino]methyl moiety as a bioisoster of aryl. A novel class of completely aliphatic beta-adrenergic receptor antagonists.
Journal of medicinal chemistry 1994;37(10):1518-25.
1994: Perioli L; Ambrogi V; Grandolini G; Giusti L; Lucacchini A; Martini C
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. VIII-Synthesis and inhibition of benzodiazepine receptor binding of some derivatives of triazino[3,4-c]-1,4-benzothiazine and triazino[3,4-d]-1,5-benzothiazepine, two new heterocyclic ring systems.
Farmaco (Società chimica italiana : 1989) 1994;49(4):245-51.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
N(6)-substituted 2-phenyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. A comparison with 2-N-butyl analogous derivatives. V.
Farmaco (Società chimica italiana : 1989) 1994;49(3):187-91.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
N(6)-substituted 2-N-butyl-9-benzyl-8-azaadenines. Affinity for adenosine A1 and A2 receptors. IV.
Farmaco (Società chimica italiana : 1989) 1994;49(3):183-6.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Martini C; Tacchi P; Merlino S; Pasero M
1,2,3-Triazole[4,5-d]pyridazines--II. New derivatives tested on adenosine receptors.
Farmaco (Società chimica italiana : 1989) 1994;49(3):175-81.
1994: Biagi G; Giorgi I; Livi O; Scartoni V; Lucacchini A; Martini C; Tacchi P
2-Aryl-8-azaadenosines: structure-activity relationships in the binding with A1 and A2 receptors. A comparison with the corresponding 9-benzyl-8-azaadenines. III.
Farmaco (Società chimica italiana : 1989) 1994;49(2):93-6.
1994: Catarzi D; Cecchi L; Colotta V; Filacchioni; Martini C; Giusti L; Lucacchini A; Valle G
Tricyclic heteroaromatic systems. 2-Phenyl-1,2,4-triazolo[1,5-c][1,3]benzoxazin-5-one: a novel benzodiazepine receptor ligand.
Farmaco (Società chimica italiana : 1989) 1994;49(2):89-92.
1994: Polidori R; Tacchi P; Azzará A; Martini C; Lucacchini A; Ferrara M P; Ambrogi F
3H-NECA binding to polymorphonuclear membrane: effect of sera from patients with Hodgkin's disease.
Cancer investigation 1994;12(2):132-7.
1994: Marazziti D; Rotondo A; Martini C; Giannaccini G; Lucacchini A; Pancioli-Guadagnucci M L; Diamond B I; Borison R; Cassano G B
Changes in peripheral benzodiazepine receptors in patients with panic disorder and obsessive-compulsive disorder.
Neuropsychobiology 1994;29(1):8-11.
1994: Martini C; Tacchi P; Bazzichi L; Fiorini M; Bondi F; Ciompi M L; Lucacchini A
A2 adenosine receptors in neutrophils from healthy volunteers and patients with rheumatoid arthritis.
Advances in experimental medicine and biology 1994;370():407-10.
1994: Martini C; Montali U; Giusti L; Fiorini M; Falleni A; Gremigni V; Lucacchini A
A1 adenosine receptors in human neutrophils: electron microscope localization using a colloidal CHA-gold-albumin probe.
Advances in experimental medicine and biology 1994;370():401-5.
1993: Mazzoni M R; Martini C; Lucacchini A
Regulation of agonist binding to A2A adenosine receptors: effects of guanine nucleotides (GDP[S] and GTP[S]) and Mg2+ ion.
Biochimica et biophysica acta 1993;1220(1):76-84.
1993: Giannaccini G; Martini C; Lucacchini A; Strettoi E; Piccolino M
The peripheral-type benzodiazepine receptor ligands [3H]Ro 5-4864 and [3H]PK 11195 bind to the retina of rabbit, but not of turtle.
Journal of neurochemistry 1993;61(4):1263-9.
1993: Macchia B; Balsamo A; Breschi M C; Chiellini G; Lapucci A; Macchia M; Manera C; Martinelli A; Martini C; Scatizzi R
Conformationally restrained analogs of sympathomimetic catecholamines. Synthesis, conformational analysis, and adrenergic activity of isochroman derivatives.
Journal of medicinal chemistry 1993;36(21):3077-86.
1993: Biagi G; Giorgi I; Livi O; Lucacchini A; Martini C; Scartoni V
Studies on specific inhibition of benzodiazepine receptor binding by some C-benzoyl-1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1993;82(9):893-6.
1993: Catarzi D; Cecchi L; Colotta V; Melani F; Filacchioni G; Martini C; Giusti L; Lucacchini A
Tricyclic heteroaromatic systems 1,2,4-triazolo[1,5-a]quinoxalines: synthesis and benzodiazepine receptor activity.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1065-78.
1993: Colotta V; Cecchi L; Catarzi D; Conti G; Filacchioni G; Martini C; Giusti L; Lucacchini A
Tricyclic heteroaromatic systems pyrazolo[1,5-a]quinoxalines: synthesis and benzodiazepine receptor activity.
Farmaco (Società chimica italiana : 1989) 1993;48(8):1051-63.
1993: Ambrogi V; Grandolini G; Perioli L; Giusti L; Lucacchini A; Martini C
Studies on annelated 1,4-benzothiazines and 1,5-benzothiazepines. VII. Synthesis and inhibition of benzodiazepine receptor binding of some 4,5-dihydro-tetrazolo[5,1-d]-1,5-benzothiazepines and 5-phenyl-s-triazolo[3,4-d]-1,5-benzothiazepines.
Farmaco (Società chimica italiana : 1989) 1993;48(5):665-76.
1993: Catarzi D; Cecchi L; Colotta V; Conti G; Melani F; Filacchioni G; Martini C; Giusti L; Lucacchini A
Reaction of 1-aminophthalazines with alpha-halocarbonyl compounds: imidazo[2,1-a]phthalazines and their benzodiazepine receptor activities.
Farmaco (Società chimica italiana : 1989) 1993;48(4):447-57.
1993: Giusti L; Belfiore M S; Martini C; Lucacchini A
3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
The Journal of steroid biochemistry and molecular biology 1993;45(4):309-14.
1993: Bruni F; Costanzo A; Selleri S; Guerrini G; Giusti L; Martini C; Lucacchini A
Synthesis of 7-(2-dimethylaminovinyl) derivatives of pyrazolo[1,5-a] pyrimidines, as precursors of new tricyclic series. Binding studies of BDZ receptor.
Farmaco (Società chimica italiana : 1989) 1993;48(2):309-19.
1993: Da Settimo A; Primofiore G; Da Settimo F; Lucacchini A; Martini C; Senatore G
Benzodiazepine receptor affinity and interaction of new indole derivatives.
Farmaco (Società chimica italiana : 1989) 1993;48(2):285-95.
1993: Da Settimo A; Primofiore G; Da Settimo F; Bianucci A; Martini C; Senatore G; Lucacchini A
Synthesis and benzodiazepine receptor affinity of N-(indol-3-ylglyoxylyl)-dipeptide derivatives. Structural requirements for inverse agonist/antagonist receptor interactions.
Drug design and discovery 1993;10(3):199-211.
1993: Colotta V; Cecchi L; Catarzi D; Melani F; Filacchioni G; Martini C; Tacchi P; Lucacchini A
Novel adenosine receptor ligands: 1,3-disubstituted[1]benzopyrano[2,3-c]pyrazol-4-ones. Synthesis and structure-activity relationships.
Receptors & channels 1993;1(2):111-9.
1992: Colotta V; Cecchi L; Melani F; Catarzi D; Filacchioni G; Martini C; Giannaccini G; Tonelli M; Lucacchini A
Tricyclic heteroaromatic systems. Synthesis and benzodiazepine binding activity of 1-substituted-3-methyl- and 3-phenylpyrazolo[4,5-c]quinolin-4-ones.
Drug design and discovery 1992;8(4):325-39.
1992: Biagi G; Livi O; Lucacchini A; Martini C; Scartoni V
Specific inhibition of binding to benzodiazepine receptors by 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1992;81(6):543-5.
1992: Bianucci A M; Da Settimo A; Da Settimo F; Primofiore G; Martini C; Giannaccini G; Lucacchini A
Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.
Journal of medicinal chemistry 1992;35(12):2214-20.
1992: Macchia B; Balsamo A; Breschi M C; Lapucci A; Lucacchini A; Macchia F; Manera C; Martinelli A; Martini C; Martinotti E
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of alpha- and beta-adrenergic receptors.
Journal of medicinal chemistry 1992;35(6):1009-18.
1992: Giannaccini G; Giacomelli M; Martini C; Lucacchini A; Piccolino M
Binding of the benzodiazepine ligand [3H]-RO 15-1788 to membrane preparations of the rabbit and turtle retina.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1992;101(2):337-42.
1992: Giusti L; Belfiore S; Martini C; Lucacchini A
Sex steroid hormones and GABAA receptor complex modulation.
Advances in biochemical psychopharmacology 1992;47():133-41.
1991: Colotta V; Cecchi L; Melani F; Filacchioni G; Martini C; Gelli S; Lucacchini A
Tricyclic heteroaromatic systems. Synthesis of 1,3 and 1,2 disubstituted [1]benzopyrano[4,3-b]pyrrol-4-ones and structure-activity relationships as benzodiazepine receptor ligands.
Farmaco (Società chimica italiana : 1989) 1991;46(10):1139-54.
1991: Colotta V; Cecchi L; Melani F; Filacchioni G; Martini C; Gelli S; Lucacchini A
Tricyclic heteroaromatic systems: [1]benzopyrano-pyrazol-4-ones as benzodiazepine receptor ligands.
Journal of pharmaceutical sciences 1991;80(3):276-9.
1991: Bonuccelli U; Nuti A; Del Dotto P; Piccini P; Martini C; Giannaccini G; Lucacchini A; Muratorio A
Platelet peripheral benzodiazepine receptors are decreased in Parkinson's disease.
Life sciences 1991;48(12):1185-90.
1991: Martini C; Di Sacco S; Tacchi P; Bazzichi L; Soletti A; Bondi F; Ciompi M L; Lucacchini A
A2 adenosine receptors in neutrophils from healthy volunteers and patients with rheumatic disease.
Advances in experimental medicine and biology 1991;309A():459-62.
1991: Martini C; Montali U; Giusti L; Giannaccini G; Falleni A; Gremigni V; Lucacchini A
A ferritin-cyclohexyladenosine probe for electron microscope localization of A1 adenosine receptor.
Advances in experimental medicine and biology 1991;309A():451-4.
1990: Colotta V; Cecchi L; Melani F; Filacchioni G; Martini C; Giannaccini G; Lucacchini A
Tricyclic heteroaromatic systems. [1]benzopyranopyrrol-4-ones and [1]benzopyrano-1,2,3-triazol-4-ones as benzodiazepine receptor ligands. Synthesis and structure-activity relationships.
Journal of medicinal chemistry 1990;33(9):2646-51.
1990: Primofiore G; Marini A M; Da Settimo F; Salvadori C; Martini C; Lucacchini A; Giannaccini G
Specific inhibition of benzodiazepine receptor binding by some N-(2-methyl or 1,2-dimethylindol-3-ylglyoxylyl)amino acid derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(3):341-51.
1990: Marazziti D; Michelini S; Giannaccini G; Martini C; Castrogiovanni P; Cassano G B; Lucacchini A
Stress-related changes of benzodiazepine binding inhibitory activity (B.B.I.A.) in humans.
Life sciences 1990;46(25):1833-6.
1990: Marazziti D; Michelini S; Martini C; Giannaccini G; Cassano G B; Lucacchini A
Benzodiazepine binding inhibitory activity (B.B.I.A.) in human plasma.
Advances in biochemical psychopharmacology 1990;46():213-20.
1989: Primofiore G; Marini A M; Da Settimo F; Martini C; Bardellini A; Giannaccini G; Lucacchini A
Specific inhibition of benzodiazepine receptor binding by some N-(indol-3-ylglyoxylyl)amino acid derivatives: stereoselective interactions.
Journal of medicinal chemistry 1989;32(12):2514-8.
1989: Melani F; Cecchi L; Colotta V; Filacchioni G; Martini C; Giannaccini G; Lucacchini A
Dipyrazolo[5,4-b:3',4'-d]pyridines. Synthesis, inhibition of benzodiazepine receptor binding and structure-activity relationships.
Farmaco (Società chimica italiana : 1989) 1989;44(6):585-94.
1989: Cecchi L; Colotta V; Melani F; Palazzino G; Filacchioni G; Martini C; Giannaccini G; Lucacchini A
Synthesis of 1,5-diaryl-3-methyl-1H-pyrazolo[4,5-c]isoquinolines and studies of binding to specific peripheral benzodiazepine binding sites.
Journal of pharmaceutical sciences 1989;78(6):437-42.
1989: Colotta V; Cecchi L; Melani F; Palazzino G; Filacchioni G; Martini C; Giannaccini G; Lucacchini A
Tricyclic heteroaromatic systems: synthesis, [3H]flunitrazepam brain membrane binding inhibition, and structure-activity relationships of 2,3-dihydro-2-aryl-4-R-[1]benzopyrano[4,3-c]pyrazole-3-ones.
Journal of pharmaceutical sciences 1989;78(3):239-42.
1989: Mazzoni M R; Giannaccini G; Lena F; Martini C; Bazzichi L; Ciompi M L; Lucacchini A
Urate binding globulin, interactions with immunoglobulins.
Advances in experimental medicine and biology 1989;253A():233-7.
1989: Martini C; Giannaccini G; Lucacchini A; Bazzichi L; Soletti A; Ciompi M L
A1 and A2 adenosine receptors in synovial cells from patients with rheumatic diseases.
Advances in experimental medicine and biology 1989;253B():429-33.
1989: Giannaccini G; Gammarota S; Martini C; Lucacchini A; Piccolino M
Binding of [3H] muscimol to the retina of rabbit and turtle.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1989;94(1):271-5.
1989: Marazziti D; Michelini S; Martini C; Giannaccini G; Lucacchini A; Cassano G B
Further investigation on benzodiazepine binding inhibitory activity in patients with major depression or panic disorder and in healthy volunteers.
Neuropsychobiology 1989;21(1):14-6.
1988: Martini C; Marrucci W; Lucacchini A; Biagi G; Livi O
Specific inhibition of benzodiazepine receptor binding by some 1,2,3-triazole derivatives.
Journal of pharmaceutical sciences 1988;77(11):977-80.
1988: Macchia B; Balsamo A; Lapucci A; Macchia F; Manera C; Nencetti S; Breschi M C; Lucacchini A; Martini C; Martinotti E
An anomalous effect of N-isopropyl substitution in determining beta-adrenergic activity.
Drug design and delivery 1988;2(4):257-62.
1988: Colotta V; Cecchi L; Filacchioni G; Melani F; Palazzino G; Martini C; Giannaccini G; Lucacchini A
Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands.
Journal of medicinal chemistry 1988;31(1):1-3.
1987: Palazzino G; Cecchi L; Melani F; Colotta V; Filacchioni G; Martini C; Lucacchini A
1,3-Diarylpyrazolo[4,5-c]- and -[5,4-c]quinolin-4-ones. 4. Synthesis and specific inhibition of benzodiazepine receptor binding.
Journal of medicinal chemistry 1987;30(10):1737-42.
1987: Balsamo A; Giorgi I; Lapucci A; Lucacchini A; Macchia B; Macchia F; Martini C; Rossi A
3-[(2-ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity.
Journal of medicinal chemistry 1987;30(1):222-5.
1987: Marazziti D; Pietrini P; Martini C; Giannaccini G; Perugi G; Placidi G F; Cassano G B; Lucacchini A
A 3H-flunitrazepam binding inhibitor is present in psychiatric patients' sera.
Neuropsychobiology 1987;18(2):74-6.
1986: Melani F; Cecchi L; Palazzino G; Filacchioni G; Martini C; Pennacchi E; Lucacchini A
Pyrazolo[4,5-c]quinolines. 3. Synthesis, receptor binding, and 13C NMR study.
Journal of pharmaceutical sciences 1986;75(12):1175-9.
1986: Melani F; Cecchi L; Palazzino G; Filacchioni G; Martini C; Pennacchi E; Lucacchini A
Pyrazolo[4,5-c]quinolines. 2. Synthesis and specific inhibition of benzodiazepine receptor binding.
Journal of medicinal chemistry 1986;29(2):291-5.
1985: Cecchi L; Melani F; Palazzino G; Filacchioni G; Martini C; Pennacchi E; Lucacchini A
Synthesis and binding studies of 1-arylpyrazolo[4,5-c]- and 2-arylpyrazolo[4,3-c]quinolin-4-ones. I.
Il Farmaco; edizione scientifica 1985;40(7):509-16.
1985: Martini C; Gervasio T; Lucacchini A; Da Settimo A; Primofiore G; Marini A M
Specific inhibition of benzodiazepine receptor binding by some N-(indol-3-ylglyoxylyl)amino acid derivatives.
Journal of medicinal chemistry 1985;28(4):506-9.

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