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Jean-Claude Martinou

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Alexis A Jourdain; Mirko Koppen; Robert N Lightowlers; Chris D Rodley; Mateusz Wydro; Zofia M Chrzanowska-Lightowlers; Jean-Claude Martinou
GRSF1 regulates RNA processing in mitochondrial RNA granules.
Syam Prakash Somasekharan; Poul H B Sorensen; Olivier Micheau; Alexandre Morizot; Ladislav Andera; Olivier Gaide; Michal Koc; Jean-Claude Martinou
TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis.
Tom Bender; Jean-Claude Martinou
Where killers meet--permeabilization of the outer mitochondrial membrane during apoptosis.

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2013: Alexis A Jourdain; Mirko Koppen; Robert N Lightowlers; Chris D Rodley; Mateusz Wydro; Zofia M Chrzanowska-Lightowlers; Jean-Claude Martinou
GRSF1 regulates RNA processing in mitochondrial RNA granules.
Cell metabolism 2013;17(3):399-410.
2013: Syam Prakash Somasekharan; Poul H B Sorensen; Olivier Micheau; Alexandre Morizot; Ladislav Andera; Olivier Gaide; Michal Koc; Jean-Claude Martinou
TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis.
Apoptosis : an international journal on programmed cell death 2013;18(3):324-36.
2013: Tom Bender; Jean-Claude Martinou
Where killers meet--permeabilization of the outer mitochondrial membrane during apoptosis.
Cold Spring Harbor perspectives in biology 2013;5(1):a011106.
2012: Friederike-Nora Vögtle; René P Zahedi; Sanjana Rao; Albert Sickmann; Julia M Burkhart; Agnieszka Chacinska; Carolin Gerbeth; Jens Hinrichs; Jean-Claude Martinou; Chris Meisinger
Intermembrane space proteome of yeast mitochondria.
Molecular & cellular proteomics : MCP 2012;11(12):1840-52.
2012: Sébastien Herzig; Edmund R S Kunji; Sylvie Montessuit; Etienne Raemy; Jean-Luc Veuthey; Benedikt Westermann; Nicola Zamboni; Jean-Claude Martinou
Identification and functional expression of the mitochondrial pyruvate carrier.
Science (New York, N.Y.) 2012;337(6090):93-6.
2012: Alexander Pintzas; Sylvie Robine; Boris Zhivotovsky; Juan Carlos Lacal; Spiros Linardopoulos; Jean-Claude Martinou; Georgios Nasioulas; Ladislav Andera
Sensitization of (colon) cancer cells to death receptor related therapies: a report from the FP6-ONCODEATH research consortium.
Cancer biology & therapy 2012;13(7):458-66.
2011: Karina von der Malsburg; Bettina Warscheid; Sebastian Wiese; Ralf M Zerbes; Marten Veenhuis; Thomas Becker; Maria Bohnert; Agnieszka Chacinska; Dana P Hutu; Paulina Kwiatkowska; Adrianna Loniewska-Lwowska; Jean-Claude Martinou; Chris Meisinger; Helmut E Meyer; Dusanka Milenkovic; Judith M Müller; Silke Oeljeklaus; Nikolaus Pfanner; Sanjana Rao; Peter Rehling; Sabine Rospert; Agnes Schulze-Specking; Ida J van der Klei; Martin van der Laan
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis.
Developmental cell 2011;21(4):694-707.
2011: Jean-Claude Martinou; Richard J Youle
Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.
Developmental cell 2011;21(1):92-101.
2011: Virginie Guillet; Naïg Gueguen; Romain Cartoni; Arnaud Chevrollier; Valérie Desquiret; Claire Angebault; Patrizia Amati-Bonneau; Vincent Procaccio; Dominique Bonneau; Jean-Claude Martinou; Pascal Reynier
Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(5):1618-27.
2011: Thomas Landes; Jean-Claude Martinou
Mitochondrial outer membrane permeabilization during apoptosis: the role of mitochondrial fission.
Biochimica et biophysica acta 2011;1813(4):540-5.
2010: Jean-Claude Martinou
[Mitochondrial dynamics: from geometry to function].
Médecine sciences : M/S 2010;26(10):783-5.
2010: Sylvie Montessuit; Syam Prakash Somasekharan; Oihana Terrones; Safa Lucken-Ardjomande; Sébastien Herzig; Robert Schwarzenbacher; Dietmar J Manstein; Ella Bossy-Wetzel; gorka basañez; Paolo Meda; Jean-Claude Martinou
Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization.
Cell 2010;142(6):889-901.
2010: Romain Cartoni; Estelle Arnaud; Jean-Jacques Médard; Olivier Poirot; Delphine S Courvoisier; R Chrast; Jean-Claude Martinou
Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.
Brain : a journal of neurology 2010;133(Pt 5):1460-9.
2010: Alexis Jourdain; Jean-Claude Martinou
Mitochondrial dynamics: quantifying mitochondrial fusion in vitro.
BMC biology 2010;8():99.
2010: Sandrine Da Cruz; Umberto De Marchi; Maud Frieden; Philippe A Parone; Jean-Claude Martinou; Nicolas Demaurex
SLP-2 negatively modulates mitochondrial sodium-calcium exchange.
Cell calcium 2010;47(1):11-8.
2009: Sarah Ehses; Ines Lauria; Giuseppe Mancuso; Andrea Bernacchia; Stefan Geimer; Daniel Tondera; Jean-Claude Martinou; Benedikt Westermann; Elena I Rugarli; Thomas Langer
Regulation of OPA1 processing and mitochondrial fusion by m-AAA protease isoenzymes and OMA1.
The Journal of cell biology 2009;187(7):1023-36.
2009: Alexis Jourdain; Jean-Claude Martinou
Mitochondrial outer-membrane permeabilization and remodelling in apoptosis.
The international journal of biochemistry & cell biology 2009;41(10):1884-9.
2009: Jean-Claude Martinou; Guido Kroemer
Autophagy: evolutionary and pathophysiological insights.
Biochimica et biophysica acta 2009;1793(9):1395-6.
2009: Simona Chera; Luiza M GHILA; Kevin Dobretz; Yvan Wenger; Christoph Bauer; Wanda Buzgariu; Jean-Claude Martinou; Brigitte Galliot
Apoptotic cells provide an unexpected source of Wnt3 signaling to drive hydra head regeneration.
Developmental cell 2009;17(2):279-89.
2009: Romain Cartoni; Jean-Claude Martinou
Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A.
Experimental neurology 2009;218(2):268-73.
2009: Daniel Tondera; Stéphanie Grandemange; Alexis Jourdain; Mariusz Karbowski; Yves Mattenberger; Sébastien Herzig; Sandrine Da Cruz; Pascaline Clerc; Ines Lauria; Carsten Merkwirth; Sarah Ehses; Frank Krause; David C Chan; Christiane Alexander; Christoph Bauer; Richard Youle; Thomas Langer; Jean-Claude Martinou
SLP-2 is required for stress-induced mitochondrial hyperfusion.
The EMBO journal 2009;28(11):1589-600.
2009: Vincent Menuz; Kate S Howell; Sébastien Gentina; Sharon Epstein; Isabelle Riezman; Monique Fornallaz-Mulhauser; Michael O. Hengartner; Marie Gomez; Howard Riezman; Jean-Claude Martinou
Protection of C. elegans from anoxia by HYL-2 ceramide synthase.
Science (New York, N.Y.) 2009;324(5925):381-4.
2009: Stéphanie Grandemange; Sébastien Herzig; Jean-Claude Martinou
Mitochondrial dynamics and cancer.
Seminars in cancer biology 2009;19(1):50-6.
2008: Kyu-Sang Park; Andreas Wiederkehr; Clare Kirkpatrick; Yves Mattenberger; Jean-Claude Martinou; Piero Marchetti; Nicolas Demaurex; Claes B Wollheim
Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells.
The Journal of biological chemistry 2008;283(48):33347-56.
2008: Stefan Mohr; Stéphanie Grandemange; Paola Massimi; Gholamreza Darai; Lawrence Banks; Jean-Claude Martinou; Martin Zeier; Walter Muranyi
Targeting the retinoblastoma protein by MC007L, gene product of the molluscum contagiosum virus: detection of a novel virus-cell interaction by a member of the poxviruses.
Journal of virology 2008;82(21):10625-33.
2008: Dominic I James; Jean-Claude Martinou
Mitochondrial dynamics and apoptosis: a painful separation.
Developmental cell 2008;15(3):341-3.
2008: Safa Lucken-Ardjomande; Jean-Claude Martinou
Granzyme a, a stealth killer in the mitochondrion.
Cell 2008;133(4):568-70.
2008: Sandrine Da Cruz; Philippe A Parone; Philippe Gonzalo; Willy V Bienvenut; Daniel Tondera; Alexis Jourdain; Manfredo Quadroni; Jean-Claude Martinou
SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.
Biochimica et biophysica acta 2008;1783(5):904-11.
2008: Safa Lucken-Ardjomande; Sylvie Montessuit; Jean-Claude Martinou
Contributions to Bax insertion and oligomerization of lipids of the mitochondrial outer membrane.
Cell death and differentiation 2008;15(5):929-37.
2008: Sébastien Herzig; Jean-Claude Martinou
Mitochondrial dynamics: to be in good shape to survive.
Current molecular medicine 2008;8(2):131-7.
2008: Safa Lucken-Ardjomande; Sylvie Montessuit; Jean-Claude Martinou
Bax activation and stress-induced apoptosis delayed by the accumulation of cholesterol in mitochondrial membranes.
Cell death and differentiation 2008;15(3):484-93.
2008: Philippe A Parone; Sandrine Da Cruz; Daniel Tondera; Yves Mattenberger; Dominic I James; Pierre Maechler; François Barja; Jean-Claude Martinou
Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA.
PloS one 2008;3(9):e3257.
2008: Sandrine Da Cruz; Jean-Claude Martinou
Purification and proteomic analysis of the mouse liver mitochondrial inner membrane.
Methods in molecular biology (Clifton, N.J.) 2008;432():101-16.
2007: Luiza K Sanjuán Szklarz; Vera Kozjak-Pavlovic; Friederike-Nora Vögtle; Agnieszka Chacinska; Dusanka Milenkovic; Sandra Vogel; Mark Dürr; Benedikt Westermann; bernard guiard; Jean-Claude Martinou; Christoph Borner; Nikolaus Pfanner; Chris Meisinger
Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins.
Journal of molecular biology 2007;368(1):44-54.
2007: Dominic James; Philippe A Parone; Olivier Terradillos; Safa Lucken-Ardjomande; Sylvie Montessuit; Jean-Claude Martinou
Mechanisms of mitochondrial outer membrane permeabilization.
Novartis Foundation symposium 2007;287():170-6; discussion 176-82.
2006: Emilie Alirol; Dominic James; Denise Huber; Andrea Marchetto; Lodovica Vergani; Jean-Claude Martinou; LUCA SCORRANO
The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis.
Molecular biology of the cell 2006;17(11):4593-605.
2006: Young-Sil Yoon; Dong-Sun Yoon; In Kyoung Lim; Soo-Han Yoon; Hae-Young Chung; Manuel Rojo; Florence Malka; Mei-Jie Jou; Jean-Claude Martinou; Gyesoon Yoon
Formation of elongated giant mitochondria in DFO-induced cellular senescence: involvement of enhanced fusion process through modulation of Fis1.
Journal of cellular physiology 2006;209(2):468-80.
2006: Philippe A Parone; Dominic I James; Sandrine Da Cruz; Yves Mattenberger; Olivier Donzé; François Barja; Jean-Claude Martinou
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
Molecular and cellular biology 2006;26(20):7397-408.
2006: Mark J Barsoum; Hua Yuan; Akos A Gerencser; Géraldine Liot; Yulia Kushnareva; Simone Gräber; Imre Kovacs; Wilson D Lee; Jenna Waggoner; Jiankun Cui; Andrew D White; Blaise Bossy; Jean-Claude Martinou; Richard J Youle; Stuart A Lipton; Mark H Ellisman; Guy A Perkins; Ella Bossy-Wetzel
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.
The EMBO journal 2006;25(16):3900-11.
2006: E Alirol; Jean-Claude Martinou
Mitochondria and cancer: is there a morphological connection?
Oncogene 2006;25(34):4706-16.
2006: Jean-Claude Martinou; R J Youle
Which came first, the cytochrome c release or the mitochondrial fission?
Cell death and differentiation 2006;13(8):1291-5.
2006: Philippe A Parone; Jean-Claude Martinou
Mitochondrial fission and apoptosis: an ongoing trial.
Biochimica et biophysica acta 2006;1763(5-6):522-30.
2005: Claudio Hetz; Pierre-Alain Vitte; Agnes Bombrun; Tatiana K Rostovtseva; Sylvie Montessuit; Agnes Hiver; Matthias K Schwarz; Dennis J Church; Stanley J Korsmeyer; Jean-Claude Martinou; Bruno Antonsson
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.
The Journal of biological chemistry 2005;280(52):42960-70.
2005: Muriel Priault; Bénédicte Salin; J Schaeffer; François M Vallette; Jean-Paul di Rago; Jean-Claude Martinou
Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast.
Cell death and differentiation 2005;12(12):1613-21.
2005: Sandrine Da Cruz; Philippe A Parone; Jean-Claude Martinou
Building the mitochondrial proteome.
Expert review of proteomics 2005;2(4):541-51.
2005: Silvia Campello; Umberto De Marchi; Ildikò Szabò; Francesco Tombola; Jean-Claude Martinou; Mario Zoratti
The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax.
FEBS letters 2005;579(17):3695-700.
2005: Safa Lucken-Ardjomande; Jean-Claude Martinou
Regulation of Bcl-2 proteins and of the permeability of the outer mitochondrial membrane.
Comptes rendus biologies 2005;328(7):616-31.
2005: Alexander Goonesinghe; Elizabeth S Mundy; Melanie Smith; Roya Khosravi-Far; Jean-Claude Martinou; Mauro Degli Esposti
Pro-apoptotic Bid induces membrane perturbation by inserting selected lysolipids into the bilayer.
The Biochemical journal 2005;387(Pt 1):109-18.
2005: Safa Lucken-Ardjomande; Jean-Claude Martinou
Newcomers in the process of mitochondrial permeabilization.
Journal of cell science 2005;118(Pt 3):473-83.
2005: Safa Lucken-Ardjomande; Sylvie Montessuit; Jean-Claude Martinou
[Changes in the outer mitochondrial membranes during apoptosis].
Journal de la Société de biologie 2005;199(3):207-10.
2004: Umberto De Marchi; Silvia Campello; Ildikò Szabò; Francesco Tombola; Jean-Claude Martinou; Mario Zoratti
Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.
The Journal of biological chemistry 2004;279(36):37415-22.
2004: Maud Frieden; Dominic James; Cyril Castelbou; Anne Danckaert; Jean-Claude Martinou; Nicolas Demaurex
Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1.
The Journal of biological chemistry 2004;279(21):22704-14.
2004: Delphine Poncet; Nathanael Larochette; Anne-Laure Pauleau; Marian Mellen; Abdelali JALIL; Pierre-Francois Cartron; François M Vallette; Céline Schnebelen; Laura M Bartle; Anna Skaletskaya; David Boutolleau; Jean-Claude Martinou; Victor S Goldmacher; Guido Kroemer; Naoufal Zamzami
An anti-apoptotic viral protein that recruits Bax to mitochondria.
The Journal of biological chemistry 2004;279(21):22605-14.
2004: Judith Henry-Mowatt; Caroline Dive; Jean-Claude Martinou; Dominic James
Role of mitochondrial membrane permeabilization in apoptosis and cancer.
Oncogene 2004;23(16):2850-60.
2004: Anne Crausaz Esseiva; Anne-Laure Chanez; Natacha Bochud-Allemann; Jean-Claude Martinou; Andrew Hemphill; André Schneider
Temporal dissection of Bax-induced events leading to fission of the single mitochondrion in Trypanosoma brucei.
EMBO reports 2004;5(3):268-73.
2004: Raquel F Epand; Jean-Claude Martinou; Sylvie Montessuit; Richard M Epand
Fatty acids enhance membrane permeabilization by pro-apoptotic Bax.
The Biochemical journal 2004;377(Pt 2):509-16.
2003: Raquel F Epand; Jean-Claude Martinou; Sylvie Montessuit; Richard M Epand
Transbilayer lipid diffusion promoted by Bax: implications for apoptosis.
Biochemistry 2003;42(49):14576-82.
2003: Paul Jolicoeur; Chunyan Hu; Tak W Mak; Jean-Claude Martinou; Denis George Kay
Protection against murine leukemia virus-induced spongiform myeloencephalopathy in mice overexpressing Bcl-2 but not in mice deficient for interleukin-6, inducible nitric oxide synthetase, ICE, Fas, Fas ligand, or TNF-R1 genes.
Journal of virology 2003;77(24):13161-70.
2003: Sandrine Da Cruz; Ioannis Xenarios; James Langridge; Francis Vilbois; Philippe A Parone; Jean-Claude Martinou
Proteomic analysis of the mouse liver mitochondrial inner membrane.
The Journal of biological chemistry 2003;278(42):41566-71.
2003: Dominic I James; Philippe A Parone; Yves Mattenberger; Jean-Claude Martinou
hFis1, a novel component of the mammalian mitochondrial fission machinery.
The Journal of biological chemistry 2003;278(38):36373-9.
2003: Steven F Nothwehr; Jean-Claude Martinou
A retention factor keeps death at bay.
Nature cell biology 2003;5(4):281-3.
2003: Yves Mattenberger; Dominic I James; Jean-Claude Martinou
Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin.
FEBS letters 2003;538(1-3):53-9.
2003: Philippe A Parone; Muriel Priault; Dominic James; Steven F Nothwehr; Jean-Claude Martinou
Apoptosis: bombarding the mitochondria.
Essays in biochemistry 2003;39():41-51.
2002: Damien Arnoult; Philippe A Parone; Jean-Claude Martinou; Bruno Antonsson; Jérôme Estaquier; Jean-Claude Ameisen
Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli.
The Journal of cell biology 2002;159(6):923-9.
2002: Xavier Roucou; Sylvie Montessuit; Bruno Antonsson; Jean-Claude Martinou
Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.
The Biochemical journal 2002;368(Pt 3):915-21.
2002: Raquel F Epand; Jean-Claude Martinou; Sylvie Montessuit; Richard M Epand; Christopher M Yip
Direct evidence for membrane pore formation by the apoptotic protein Bax.
Biochemical and biophysical research communications 2002;298(5):744-9.
2002: Raquel F Epand; Jean-Claude Martinou; Sylvie Montessuit; Richard M Epand
Membrane perturbations induced by the apoptotic Bax protein.
The Biochemical journal 2002;367(Pt 3):849-55.
2002: Raquel F Epand; Jean-Claude Martinou; Monique Fornallaz-Mulhauser; Donald W Hughes; Richard M Epand
The apoptotic protein tBid promotes leakage by altering membrane curvature.
The Journal of biological chemistry 2002;277(36):32632-9.
2002: Olivier Terradillos; Sylvie Montessuit; David C S Huang; Jean-Claude Martinou
Direct addition of BimL to mitochondria does not lead to cytochrome c release.
FEBS letters 2002;522(1-3):29-34.
2002: Xavier Roucou; Tatiana K Rostovtseva; Sylvie Montessuit; Jean-Claude Martinou; Bruno Antonsson
Bid induces cytochrome c-impermeable Bax channels in liposomes.
The Biochemical journal 2002;363(Pt 3):547-52.
2002: Philippe A Parone; Dominic James; Jean-Claude Martinou
Mitochondria: regulating the inevitable.
Biochimie 2002;84(2-3):105-11.
2002: Jean-Luc PERFETTINI; John C Reed; Nicole Israël; Jean-Claude Martinou; Alice Dautry-Varsat; David M Ojcius
Role of Bcl-2 family members in caspase-independent apoptosis during Chlamydia infection.
Infection and immunity 2002;70(1):55-61.
2001: Solange Desagher; A Osen-Sand; Sylvie Montessuit; E Magnenat; Francis Vilbois; A Hochmann; Laurent Journot; Bruno Antonsson; Jean-Claude Martinou
Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.
Molecular cell 2001;8(3):601-11.
2001: Xavier Roucou; Jean-Claude Martinou
Conformational change of Bax: a question of life or death.
Cell death and differentiation 2001;8(9):875-7.
2001: Bruno Antonsson; Sylvie Montessuit; B Sanchez; Jean-Claude Martinou
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells.
The Journal of biological chemistry 2001;276(15):11615-23.
2001: Xavier Roucou; Bruno Antonsson; Jean-Claude Martinou
Involvement of mitochondria in apoptosis.
Cardiology clinics 2001;19(1):45-55.
2000: Solange Desagher; Jean-Claude Martinou
Mitochondria as the central control point of apoptosis.
Trends in cell biology 2000;10(9):369-77.
2000: Grzegorz Kudla; Sylvie Montessuit; R Eskes; Catherine Berrier; Jean-Claude Martinou; Alexandre Ghazi; Bruno Antonsson
The destabilization of lipid membranes induced by the C-terminal fragment of caspase 8-cleaved bid is inhibited by the N-terminal fragment.
The Journal of biological chemistry 2000;275(30):22713-8.
2000: B Antonsson; Jean-Claude Martinou
The Bcl-2 protein family.
Experimental cell research 2000;256(1):50-7.
2000: Jean-Claude Martinou; Solange Desagher; B Antonsson
Cytochrome c release from mitochondria: all or nothing.
Nature cell biology 2000;2(3):E41-3.
2000: R Eskes; Solange Desagher; Bruno Antonsson; Jean-Claude Martinou
Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane.
Molecular and cellular biology 2000;20(3):929-35.
2000: Bruno Antonsson; Sylvie Montessuit; S Lauper; R Eskes; Jean-Claude Martinou
Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria.
The Biochemical journal 2000;345 Pt 2():271-8.
1999: Solange Desagher; A Osen-Sand; Anthony Nichols; R Eskes; Sylvie Montessuit; S Lauper; Kinsey Maundrell; Bruno Antonsson; Jean-Claude Martinou
Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis.
The Journal of cell biology 1999;144(5):891-901.
1999: Isabelle Martinou; Solange Desagher; R Eskes; Bruno Antonsson; E André; S Fakan; Jean-Claude Martinou
The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event.
The Journal of cell biology 1999;144(5):883-9.
1998: R Eskes; Bruno Antonsson; A Osen-Sand; Sylvie Montessuit; C Richter; Rémy Sadoul; GJ Mazzei; Anthony Nichols; Jean-Claude Martinou
Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions.
The Journal of cell biology 1998;143(1):217-24.
1998: Anthony Nichols; Isabelle Martinou; Kinsey Maundrell; Jean-Claude Martinou
The p75 neurotrophin receptor: effects on neuron survival in vitro and interaction with death domain-containing adaptor proteins.
Apoptosis : an international journal on programmed cell death 1998;3(4):289-94.
1998: S Lewis; S S Bethell; S Patel; Jean-Claude Martinou; Bruno Antonsson
Purification and biochemical properties of soluble recombinant human Bax.
Protein expression and purification 1998;13(1):120-6.
1998: Isabelle Martinou; Marc Missotten; P A Fernandez; Rémy Sadoul; Jean-Claude Martinou
Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons.
Neuroreport 1998;9(1):15-9.
1997: Kinsey Maundrell; Bruno Antonsson; E Magnenat; Montserrat Camps; M Muda; Christian Chabert; Corine Gillieron; U Boschert; Elisabeth Vial-Knecht; Jean-Claude Martinou; Steve Arkinstall
Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.
The Journal of biological chemistry 1997;272(40):25238-42.
1997: Bruno Antonsson; F Conti; A Ciavatta; Sylvie Montessuit; S Lewis; Isabelle Martinou; lilia bernasconi; A Bernard; J J Mermod; GJ Mazzei; Kinsey Maundrell; F Gambale; Rémy Sadoul; Jean-Claude Martinou
Inhibition of Bax channel-forming activity by Bcl-2.
Science (New York, N.Y.) 1997;277(5324):370-2.
1997: S Estoppey; ivan rodriguez; Rémy Sadoul; Jean-Claude Martinou
Bcl-2 prevents activation of CPP32 cysteine protease and cleavage of poly (ADP-ribose) polymerase and U1-70 kD proteins in staurosporine-mediated apoptosis.
Cell death and differentiation 1997;4(1):34-8.
1996: Jean-Claude Martinou; Rémy Sadoul
ICE-like proteases execute the neuronal death program.
Current opinion in neurobiology 1996;6(5):609-14.
1996: B Allet; A Hochmann; Isabelle Martinou; A Berger; Marc Missotten; Bruno Antonsson; Rémy Sadoul; Jean-Claude Martinou; lilia bernasconi
Dissecting processing and apoptotic activity of a cysteine protease by mutant analysis.
The Journal of cell biology 1996;135(2):479-86.
1996: Rémy Sadoul; P A Fernandez; A L Quiquerez; Isabelle Martinou; M Maki; M Schröter; J D Becherer; M Irmler; Jürg Tschopp; Jean-Claude Martinou
Involvement of the proteasome in the programmed cell death of NGF-deprived sympathetic neurons.
The EMBO journal 1996;15(15):3845-52.
1996: Rémy Sadoul; A L Quiquerez; Isabelle Martinou; P A Fernandez; Jean-Claude Martinou
p53 protein in sympathetic neurons: cytoplasmic localization and no apparent function in apoptosis.
Journal of neuroscience research 1996;43(5):594-601.
1996: M Muda; U Boschert; R Dickinson; Jean-Claude Martinou; Isabelle Martinou; Montserrat Camps; W Schlegel; Steve Arkinstall
MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase.
The Journal of biological chemistry 1996;271(8):4319-26.
1996: Rémy Sadoul; Michel Dubois-Dauphin; P A Fernandez; H Frankowski; A L Quiquerez; Isabelle Martinou; Marc Missotten; C Pietra; Jean-Claude Martinou
Mechanisms of neuronal cell death.
Advances in neurology 1996;71():419-23; discussion 423-4.
1995: Y Sagot; Michel Dubois-Dauphin; S A Tan; Fabienne de Bilbao; Patrick Aebischer; Jean-Claude Martinou; Ann C Kato
Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7727-33.
1995: H Frankowski; Marc Missotten; P A Fernandez; Isabelle Martinou; P Michel; Rémy Sadoul; Jean-Claude Martinou
Function and expression of the Bcl-x gene in the developing and adult nervous system.
Neuroreport 1995;6(14):1917-21.
1995: S N Farrow; J H White; Isabelle Martinou; T Raven; K T Pun; C J Grinham; Jean-Claude Martinou; R Brown
Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K.
Nature 1995;374(6524):731-3.
1995: Isabelle Martinou; P A Fernandez; Marc Missotten; E White; B Allet; Rémy Sadoul; Jean-Claude Martinou
Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation.
The Journal of cell biology 1995;128(1-2):201-8.
1994: Christoph Borner; R Olivier; Isabelle Martinou; C Mattmann; Jürg Tschopp; Jean-Claude Martinou
Dissection of functional domains in Bcl-2 alpha by site-directed mutagenesis.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(11-12):463-9.
1994: Jean-Claude Martinou; Michel Dubois-Dauphin; J K Staple; ivan rodriguez; H Frankowski; Marc Missotten; P Albertini; D Talabot; Stefan Catsicas; C Pietra
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia.
Neuron 1994;13(4):1017-30.
1994: Christoph Borner; Isabelle Martinou; C Mattmann; M Irmler; E Schaerer; Jean-Claude Martinou; Jürg Tschopp
The protein bcl-2 alpha does not require membrane attachment, but two conserved domains to suppress apoptosis.
The Journal of cell biology 1994;126(4):1059-68.
1994: Michel Dubois-Dauphin; H Frankowski; Y Tsujimoto; J Huarte; Jean-Claude Martinou
Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3309-13.
1994: M Chireux; J F Raynal; A Le Van Thai; H Cadas; C Bernard; Isabelle Martinou; Jean-Claude Martinou; Michel J Weber
Multiple promoters of human choline acetyltransferase and aromatic L-amino acid decarboxylase genes.
Journal of physiology, Paris 1994;88(4):215-27.
1994: Jean-Claude Martinou; H Frankowski; Marc Missotten; Isabelle Martinou; L Potier; Michel Dubois-Dauphin
Bcl-2 and neuronal selection during development of the nervous system.
Journal of physiology, Paris 1994;88(3):209-11.
1992: IRENE GARCIA; Isabelle Martinou; Y Tsujimoto; Jean-Claude Martinou
Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene.
Science (New York, N.Y.) 1992;258(5080):302-4.
1992: Jean-Claude Martinou; Isabelle Martinou; Ann C Kato
Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro.
Neuron 1992;8(4):737-44.
1990: Jean-Claude Martinou; A Le Van Thai; Annie Valette; Michel J Weber
Transforming growth factor beta 1 is a potent survival factor for rat embryo motoneurons in culture.
Brain research. Developmental brain research 1990;52(1-2):175-81.
1989: Jean-Claude Martinou; A Le Van Thai; G Cassar; Francis Roubinet; Michel J Weber
Characterization of two factors enhancing choline acetyltransferase activity in cultures of purified rat motoneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3645-56.
1989: Jean-Claude Martinou; F Bierer; A Le Van Thai; Michel J Weber
Influence of the culture substratum on the expression of choline acetyltransferase activity in purified motoneurons from rat embryos.
Brain research. Developmental brain research 1989;47(2):251-62.