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Hiroyuki Marusawa

Research Profile

Chemicals & Drugs

Disorders

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Anatomy

Hepatocytes

Physiology

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Liver Transplantation

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Publications

TOP 3
Yuji Eso; Hiroyuki Marusawa; Tsutomu Chiba
Platelet plays a role in the pathogenesis of hepatitis B virus-related hepatocellular carcinoma.
Yoshihide Ueda; Shinji Uemoto; Atsushi Yoshizawa; Yasuhiro Fujimoto; Hironori Haga; Koichiro Hata; Toshimi Kaido; Hiroyuki Marusawa; Aya Miyagawa-Hayashino; Kohei Ogawa; Yasuhiro Ogura; Satoshi Teramukai; Tsutomu Chiba
Pretransplant serum hepatitis C virus RNA levels predict response to antiviral treatment after living donor liver transplantation.
Yoshihide Ueda; Atsushi Yoshizawa; Tsutomu Chiba; Yasuhiro Fujimoto; Koichiro Hata; Toshimi Kaido; Hiroyuki Marusawa; N Nishijima; Kohei Ogawa; Yasuhiro Ogura; Shinji Uemoto
Efficacy and safety of prophylaxis with entecavir and hepatitis B immunoglobulin in preventing hepatitis B recurrence after living-donor liver transplantation.

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All Publications

2013: Yuji Eso; Hiroyuki Marusawa; Tsutomu Chiba
Platelet plays a role in the pathogenesis of hepatitis B virus-related hepatocellular carcinoma.
Gastroenterology 2013;144(5):1140-2.
2013: Yoshihide Ueda; Shinji Uemoto; Atsushi Yoshizawa; Yasuhiro Fujimoto; Hironori Haga; Koichiro Hata; Toshimi Kaido; Hiroyuki Marusawa; Aya Miyagawa-Hayashino; Kohei Ogawa; Yasuhiro Ogura; Satoshi Teramukai; Tsutomu Chiba
Pretransplant serum hepatitis C virus RNA levels predict response to antiviral treatment after living donor liver transplantation.
PloS one 2013;8(3):e58380.
2013: Yoshihide Ueda; Atsushi Yoshizawa; Tsutomu Chiba; Yasuhiro Fujimoto; Koichiro Hata; Toshimi Kaido; Hiroyuki Marusawa; N Nishijima; Kohei Ogawa; Yasuhiro Ogura; Shinji Uemoto
Efficacy and safety of prophylaxis with entecavir and hepatitis B immunoglobulin in preventing hepatitis B recurrence after living-donor liver transplantation.
Hepatology research : the official journal of the Japan Society of Hepatology 2013;43(1):67-71.
2012: Takahiro Shimizu; Hiroyuki Marusawa; Tsutomu Chiba
Recurrent somatic mutations in human gastric cancers identified by whole exome sequencing.
Gastroenterology 2012;143(5):1385-7.
2012: Tsutomu Chiba; Hiroyuki Marusawa; Yuko Matsumoto; Atsushi Takai
[Chronic inflammation and gastric cancer development].
Nihon rinsho. Japanese journal of clinical medicine 2012;70(10):1694-8.
2012: Yuji Eso; Hiroyuki Marusawa; Yoshihiro Okabe; Takehiko Tsumura; Yukio Osaki
Endoscopic ultrasonography-guided transgastric drainage of infectious biloma following radiofrequency ablation for hepatocellular carcinoma.
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2012;24(5):390.
2012: Tsutomu Chiba; Hiroyuki Marusawa; Toshikazu Ushijima
Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation.
Gastroenterology 2012;143(3):550-63.
2012: Takahiro Shimizu; Yoko Endo; Hiroyuki Marusawa; Tsutomu Chiba
Inflammation-mediated genomic instability: roles of activation-induced cytidine deaminase in carcinogenesis.
Cancer science 2012;103(7):1201-6.
2012: Yukio Osaki; Sumio Saito; Azusa Sakamoto; Yoshihide Ueda; Yuji Eso; Shinichiro Henmi; Toru Kimura; Ryuichi Kita; Hiroyuki Marusawa; Jun Nakajima; Hiroki Nishikawa; Tsutomu Chiba
Decrease in alpha-fetoprotein levels predicts reduced incidence of hepatocellular carcinoma in patients with hepatitis C virus infection receiving interferon therapy: a single center study.
Journal of gastroenterology 2012;47(4):444-51.
2012: A Takai; G Tsujimoto; T Watanabe; Kazuo Kinoshita; Hiroyuki Marusawa; Y Minaki; Hiroshi Nakase; Tsutomu Chiba
Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation.
Oncogene 2012;31(13):1733-42.
2012: Shunsuke Okuyama; Atsushi Takai; Yoshihide Ueda; Yoko Endo; Hiroyuki Marusawa; Tomonori Matsumoto; Yuko Matsumoto; Tsutomu Chiba
Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.
International journal of cancer. Journal international du cancer 2012;130(6):1294-301.
2012: Hiroyuki Marusawa; Atsushi Takai; Tsutomu Chiba
[Genetic alterations leading to the development of colitis-associated colorectal cancers].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 1():651-5.
2012: Y Eso; Hiroyuki Marusawa; Y Osaki
Education and imaging. Hepatobiliary and Pancreatic: Detection of early hepatocellular carcinoma by enhanced magnetic resonance imaging.
Journal of gastroenterology and hepatology 2012;27(2):416.
2012: N Nishijima; Yukio Osaki; K Shimizu; Ken Takahashi; Soken Tsuchiya; Yoshihide Ueda; Shinji Uemoto; Shujiro Yazumi; Takeshi Fujiwara; Tadayuki Kou; Hiroyuki Marusawa; Akihiro Nasu; Tsutomu Chiba
Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing.
PloS one 2012;7(4):e35052.
2011: Shuko Morita; Shunsuke Okuyama; Koh Ono; Tsuneo Oyama; Akihisa Tomori; Yuji Amano; Tsutomu Chiba; Yoshikazu Kinoshita; Yoko Kitamura; Yuko Matsumoto; Hiroyuki Marusawa
Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma.
Carcinogenesis 2011;32(11):1706-12.
2011: Tsutomu Chiba; Hiroyuki Marusawa; Yuko Matsumoto; Atsushi Takai
[The cutting-edge of medicine; inflammation and development of gastrointestinal cancers].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2011;100(8):2269-74.
2011: Takahiro Shimizu; Hiroyuki Marusawa
[Role of inflammation in the development of gastrointestinal cancers].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 2011;108(8):1374-82.
2011: Hiroyuki Marusawa; Tsutomu Chiba
A marker for dormant cancer stem cells in human hepatocellular carcinoma.
Gastroenterology 2011;140(4):1353-5; discussion 1355.
2011: Hiroyuki Marusawa; Atsushi Takai; Tsutomu Chiba
Role of activation-induced cytidine deaminase in inflammation-associated cancer development.
Advances in immunology 2011;111():109-41.
2011: Akihiro Nasu; N Nishijima; Yukio Osaki; Fumiaki Sato; K Shimizu; Ken Takahashi; Takashi Tamada; Yoshihide Ueda; Yukitaka Yamashita; Takeshi Fujiwara; Tetsuro Inokuma; Hiroyuki Marusawa; Tsutomu Chiba
Genetic heterogeneity of hepatitis C virus in association with antiviral therapy determined by ultra-deep sequencing.
PloS one 2011;6(9):e24907.
2011: Yoshihide Ueda; Shinji Uemoto; Hiroto Egawa; Hiroyuki Marusawa; N Nishijima; Yasuhiro Ogura; Fumitaka Oike; Shinya Okamoto; Yasutsugu Takada; Tsutomu Chiba
De novo activation of HBV with escape mutations from hepatitis B surface antibody after living donor liver transplantation.
Antiviral therapy 2011;16(4):479-87.
2011: Akio Ido; Il-Deok Kim; Hiroyuki Marusawa; Akihiro Moriuchi; Toshinori Murayama; Masatsugu Numata; H Setoyama; Akira Shimizu; Satoshi Teramukai; Tsutomu Chiba; Masanori Fukushima; Shuji Higuchi; Naohisa Yamaji; Masayuki Yokode; Hirohito Tsubouchi
Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety.
Journal of translational medicine 2011;9():55.
2011: Yoko Endo; Hiroyuki Marusawa; Tsutomu Chiba
Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers.
Journal of gastroenterology 2011;46 Suppl 1():6-10.
2010: Yuko Matsumoto; Hiroyuki Marusawa; Kazuo Kinoshita; Yoko Niwa; Yoshiharu Sakai; Tsutomu Chiba
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer.
Gastroenterology 2010;139(6):1984-94.
2010: Takahiro Horie; Koh Ono; Masahito Horiguchi; Hitoo Nishi; Tomoyuki Nakamura; Kazuya Nagao; Minako Kinoshita; Yasuhide Kuwabara; Hiroyuki Marusawa; Yoshitaka Iwanaga; Koji Hasegawa; Masayuki Yokode; Takeshi Kimura; Toru Kita
MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17321-6.
2010: Yoshihide Ueda; Yasutsugu Takada; Hiroyuki Marusawa; Hiroto Egawa; Shinji Uemoto; Tsutomu Chiba
Individualized extension of pegylated interferon plus ribavirin therapy for recurrent hepatitis C genotype 1b after living-donor liver transplantation.
Transplantation 2010;90(6):661-5.
2010: Tomonori Matsumoto; Hiroyuki Marusawa; Miki Dogaki; Yoshiki Suginoshita; Tetsuro Inokuma
Adalimumab-induced lethal hepatitis B virus reactivation in an HBsAg-negative patient with clinically resolved hepatitis B virus infection.
Liver international : official journal of the International Association for the Study of the Liver 2010;30(8):1241-2.
2010: Takahiro Shimizu; Hiroyuki Marusawa; Yukitaka Yamashita
Image of the month. Diaphragm-like stricture of the small intestine related to cytomegalovirus infection.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2010;8(9):A21.
2010: Hiroyuki Marusawa; Tsutomu Chiba
Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis.
Current opinion in immunology 2010;22(4):442-7.
2010: Yoshihide Ueda; Yasutsugu Takada; Hiroyuki Marusawa; Hironori Haga; Tosiya Sato; Yuetsu Tanaka; Hiroto Egawa; Shinji Uemoto; Tsutomu Chiba
Clinical features of biochemical cholestasis in patients with recurrent hepatitis C after living-donor liver transplantation.
Journal of viral hepatitis 2010;17(7):481-7.
2010: Akihiro Nasu; Hiroyuki Marusawa; Yoshihide Ueda; Yuji Eso; Makoto Umeda; Tsutomu Chiba; Yukio Osaki
De novo hepatitis B virus infection in hepatocellular carcinoma following eradication of hepatitis C virus by interferon therapy.
Hepatology research : the official journal of the Japan Society of Hepatology 2010;40(6):661-5.
2010: Takahiro Shimizu; Hiroyuki Marusawa; Yukitaka Yamashita
Pneumothorax following esophageal perforation due to ingested fish bone.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2010;8(5):A24.
2010: A Ikeda; Hiroyuki Marusawa; J Nakajima; Y Osaki
Education and Imaging. Hepatobiliary and pancreatic: Delayed ileal perforation following radiofrequency ablation of hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2010;25(2):430.
2010: Hiroyuki Marusawa
[Mechanisms of H. pylori infection-induced gastric carcinogenesis].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(1):23-7.
2009: Tsutomu Chiba; Hiroyuki Marusawa; Yuko Matsumoto
[A novel mechanism for H. pylori-induced cell damage--induction of gene mutation by AID].
Nihon rinsho. Japanese journal of clinical medicine 2009;67(12):2265-70.
2009: Kyoko Ikeuchi; Hiroyuki Marusawa; Mikio Fujiwara; Yuko Matsumoto; Yoko Endo; Tomohiro Watanabe; Akio Iwai; Yoshiharu Sakai; Ryosuke Takahashi; Tsutomu Chiba
Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers.
International journal of cancer. Journal international du cancer 2009;125(9):2029-35.
2009: Tsutomu Chiba; Hiroyuki Marusawa
A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction.
Journal of molecular medicine (Berlin, Germany) 2009;87(10):1023-7.
2009: N Nishijima; Hiroyuki Marusawa; R Kita; Y Osaki; Tsutomu Chiba
Education and Imaging. Hepatobiliary and pancreatic: spontaneous regression of hepatocellular cancer demonstrated by contrast-enhanced ultrasonography.
Journal of gastroenterology and hepatology 2009;24(6):1153.
2009: Michihiko Wada; Hiroyuki Marusawa; R Yamada; A Nasu; Y Osaki; Masatoshi Kudo; Motoshige Nabeshima; Y Fukuda; Tsutomu Chiba; Fumihiko MATSUDA
Association of genetic polymorphisms with interferon-induced haematologic adverse effects in chronic hepatitis C patients.
Journal of viral hepatitis 2009;16(6):388-96.
2009: Yoshihide Ueda; Hiroyuki Marusawa; Tatsuo Ichinohe; Norimitsu Kadowaki; Takashi Uchiyama; Tsutomu Chiba
Effective treatment for de novo hepatitis B with nucleotide analogue in patients with hematological malignancies.
American journal of hematology 2009;84(5):315-6.
2009: A Takai; T Toyoshima; M Uemura; Y Kitawaki; Hiroyuki Marusawa; Hiroshi Hiai; Shigehito Yamada; Il-mi Okazaki; Tasuku Honjo; Tsutomu Chiba; Kazuo Kinoshita
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
Oncogene 2009;28(4):469-78.
2008: Akio Ido; Kazuki Ikeda; Hiroyuki Marusawa; Akihiro Moriuchi; Masatsugu Numata; Makoto Oketani; H Setoyama; Tsutomu Chiba; Hiroshi Ida; Naohisa Yamaji; Hirohito Tsubouchi
Translational research on HGF: A phase I/II study of recombinant human HGF for the treatment of fulminant hepatic failure.
Hepatology research : the official journal of the Japan Society of Hepatology 2008;38 Suppl 1():S88-92.
2008: M Fujiwara; Hiroyuki Marusawa; H-Q Wang; Akio Iwai; K Ikeuchi; Yoichi Imai; Ayane Kataoka; Nobuyuki Nukina; Rei Takahashi; Tsutomu Chiba
Parkin as a tumor suppressor gene for hepatocellular carcinoma.
Oncogene 2008;27(46):6002-11.
2008: Yoko Endo; Hiroyuki Marusawa; Tadayuki Kou; Hiroshi Nakase; Shigehiko Fujii; Takahiro Fujimori; Kazuo Kinoshita; Tasuku Honjo; Tsutomu Chiba
Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.
Gastroenterology 2008;135(3):889-98, 898.e1-3.
2008: Tsutomu Chiba; Hiroyuki Marusawa; Hiroshi Seno; Norihiko Watanabe
Mechanism for gastric cancer development by Helicobacter pylori infection.
Journal of gastroenterology and hepatology 2008;23(8 Pt 1):1175-81.
2008: Yoshihide Ueda; Yasutsugu Takada; Hironori Haga; Motoshige Nabeshima; Hiroyuki Marusawa; Takashi Ito; Hiroto Egawa; Koichi Tanaka; Shinji Uemoto; Tsutomu Chiba
Limited benefit of biochemical response to combination therapy for patients with recurrent hepatitis C after living-donor liver transplantation.
Transplantation 2008;85(6):855-62.
2008: Junji Komori; Hiroyuki Marusawa; Takafumi Machimoto; Yoko Endo; Kazuo Kinoshita; Tadayuki Kou; Hironori Haga; Iwao Ikai; Shinji Uemoto; Tsutomu Chiba
Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.
Hepatology (Baltimore, Md.) 2008;47(3):888-96.
2008: Hiroyuki Marusawa
Aberrant AID expression and human cancer development.
The international journal of biochemistry & cell biology 2008;40(8):1399-402.
2007: Yoko Endo; Hiroyuki Marusawa; Kazuo Kinoshita; Toshiyuki Morisawa; T Sakurai; Il-mi Okazaki; Koichi Watashi; Kunitada Shimotohno; Tasuku Honjo; Tsutomu Chiba
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling.
Oncogene 2007;26(38):5587-95.
2007: Kazuki Ikeda; Hiroyuki Marusawa; Yukio Osaki; Takefumi Nakamura; Naoto Kitajima; Yukitaka Yamashita; Masatoshi Kudo; Tosiya Sato; Tsutomu Chiba
Antibody to hepatitis B core antigen and risk for hepatitis C-related hepatocellular carcinoma: a prospective study.
Annals of internal medicine 2007;146(9):649-56.
2007: Toshiyuki Morisawa; Hiroyuki Marusawa; Shigeki Ono
Spontaneous rupture of intrahepatic aneurysm.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2007;5(4):A30.
2007: Yuko Matsumoto; Hiroyuki Marusawa; Kazuo Kinoshita; Yoko Endo; Tadayuki Kou; Toshiyuki Morisawa; Takeshi Azuma; Il-mi Okazaki; Tasuku Honjo; Tsutomu Chiba
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium.
Nature medicine 2007;13(4):470-6.
2007: Tadayuki Kou; Hiroyuki Marusawa; Kazuo Kinoshita; Yoko Endo; Il-mi Okazaki; Yoshihide Ueda; Yuzo Kodama; Hironori Haga; Iwao Ikai; Tsutomu Chiba
Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.
International journal of cancer. Journal international du cancer 2007;120(3):469-76.
2006: M Umeda; Hiroyuki Marusawa; Michiko Ueda; Yasutsugu Takada; Hiroto Egawa; Shinji Uemoto; T Chiba
Beneficial effects of short-term lamivudine treatment for de novo hepatitis B virus reactivation after liver transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(11):2680-5.
2006: Ryoji Fujii; Changjun Zhu; Yunfei Wen; Hiroyuki Marusawa; Beatrice Bailly-Maitre; Shu-ichi Matsuzawa; Hong Zhang; Youngsoo Kim; C Frank Bennett; Wei Jiang; John C Reed
HBXIP, cellular target of hepatitis B virus oncoprotein, is a regulator of centrosome dynamics and cytokinesis.
Cancer research 2006;66(18):9099-107.
2006: A Iwai; Hiroyuki Marusawa; Yasutsugu Takada; Hiroto Egawa; Kazuo Ikeda; Motoshige Nabeshima; Shinji Uemoto; Tsutomu Chiba
Identification of novel defective HCV clones in liver transplant recipients with recurrent HCV infection.
Journal of viral hepatitis 2006;13(8):523-31.
2006: Chihiro Yamasaki; Chise Tateno; Akio Aratani; Chimoto Ohnishi; Shigeru Katayama; Toshihiko Kohashi; Hiroshi Hino; Hiroyuki Marusawa; Toshimasa Asahara; Katsutoshi Yoshizato
Growth and differentiation of colony-forming human hepatocytes in vitro.
Journal of hepatology 2006;44(4):749-57.
2006: Yuichi Tanaka; Hiroyuki Marusawa; Hiroshi Seno; Yuko Matsumoto; Yoshihide Ueda; Yuzo Kodama; Yoko Endo; Junichi Yamauchi; Tomonori Matsumoto; Akifumi Takaori-Kondo; Iwao Ikai; Tsutomu Chiba
Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.
Biochemical and biophysical research communications 2006;341(2):314-9.
2006: Tomonori Matsumoto; Hiroyuki Marusawa; Yoko Endo; Yoshihide Ueda; Yuko Matsumoto; Tsutomu Chiba
Expression of APOBEC2 is transcriptionally regulated by NF-kappaB in human hepatocytes.
FEBS letters 2006;580(3):731-5.
2006: Tsutomu Chiba; Hiroshi Seno; Hiroyuki Marusawa; Yoshio Wakatsuki; Kazuichi Okazaki
Host factors are important in determining clinical outcomes of Helicobacter pylori infection.
Journal of gastroenterology 2006;41(1):1-9.
2005: Makoto Umeda; Hiroyuki Marusawa; Hiroshi Seno; Akira Katsurada; Motoshige Nabeshima; Hiroto Egawa; Shinji Uemoto; Yukihiro Inomata; Koichi Tanaka; Tsutomu Chiba
Hepatitis B virus infection in lymphatic tissues in inactive hepatitis B carriers.
Journal of hepatology 2005;42(6):806-12.
2005: Yuichi Tanaka; Hironori Haga; Hiroto Egawa; Tomoko Okuno; Aya Miyagawa-Hayashino; Tsuruyama Tatsuaki; Michiyo Kambe; Hiroyuki Marusawa; Tsutomu Chiba; Toshiaki Manabe
Intragraft expression of recipient-type ABO blood group antigens: long-term follow-up and histological features after liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005;11(5):547-54.
2004: H Ali; Hiroto Egawa; Kenji Uryuhara; Kohei Ogawa; Mureo Kasahara; Michiko Ueda; Hiroyuki Marusawa; Motoshige Nabeshima; Kiyoji Tanaka
Prevention of hepatitis B virus recurrence after living donor liver transplantation.
Transplantation proceedings 2004;36(9):2764-7.
2004: Akio Iwai; Hiroyuki Marusawa; Shu-ichi Matsuzawa; Toru Fukushima; Makoto Hijikata; John C Reed; Kunitada Shimotohno; Tsutomu Chiba
Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.
Oncogene 2004;23(45):7593-600.
2004: Masahiko Kondo; Hiroyuki Marusawa; Yoshihide Ueda; Akira Katsurada; Chie Kawasome; Satoshi Takami; Moritoshi Kinoshita; Iwao Ikai; Yoshio Yamaoka; Tsutomu Chiba
Diverse p53 gene aberration in hepatocellular carcinoma detected by dual-color fluorescence in situ hybridization.
Journal of gastroenterology and hepatology 2004;19(9):1066-73.
2004: Takehiko Dohi; Kazuya Okada; Fang Xia; Casey E Wilford; Temesgen Samuel; Kate Welsh; Hiroyuki Marusawa; Hua Zou; Robert Armstrong; Shu-ichi Matsuzawa; Guy S Salvesen; John C Reed; Dario C Altieri
An IAP-IAP complex inhibits apoptosis.
The Journal of biological chemistry 2004;279(33):34087-90.
2004: Naoki Kanda; Hiroshi Seno; Yoshitaka Konda; Hiroyuki Marusawa; Masashi Kanai; Toshio Nakajima; Tomoko Kawashima; Apichart Nanakin; Tateo Sawabu; Yoshito Uenoyama; Akira Sekikawa; Mayumi Kawada; Katsumasa Suzuki; Takahisa Kayahara; Hirokazu Fukui; Mitsutaka Sawada; Tsutomu Chiba
STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.
Oncogene 2004;23(28):4921-9.
2003: Koichi Watashi; Makoto Hijikata; Ayako Tagawa; Takahiro Doi; Hiroyuki Marusawa; Kunitada Shimotohno
Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus.
Molecular and cellular biology 2003;23(21):7498-509.
2003: Hiroyuki Marusawa; Shu-ichi Matsuzawa; Kate Welsh; Hua Zou; Robert Armstrong; Ingo Tamm; John C Reed
HBXIP functions as a cofactor of survivin in apoptosis suppression.
The EMBO journal 2003;22(11):2729-40.
2003: John C Reed; Kutbuddin Doctor; Ana Rojas; Juan M Zapata; Christian Stehlik; Loredana Fiorentino; Jason S Damiano; Wilfried Roth; Shu-ichi Matsuzawa; Ruchi Newman; Shinichi Takayama; Hiroyuki Marusawa; Famming Xu; Guy S Salvesen; Adam Godzik
Comparative analysis of apoptosis and inflammation genes of mice and humans.
Genome research 2003;13(6B):1376-88.
2003: Akio Iwai; Hiroyuki Marusawa; Tetsuya Kiuchi; Hiroaki Higashitsuji; Koichi Tanaka; Jun Fujita; Tsutomu Chiba
Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferation.
Journal of gastroenterology 2003;38(8):751-8.
2002: José M Cuezva; Maryla Krajewska; Miguel Lopez de Heredia; Stanislaw Krajewski; Gorane Santamaría; Hoguen Kim; Juan M Zapata; Hiroyuki Marusawa; Margarita Chamorro; John C Reed
The bioenergetic signature of cancer: a marker of tumor progression.
Cancer research 2002;62(22):6674-81.
2002: Kunitada Shimotohno; Koichi Watashi; Katsuya Tsuchihara; Katsuhiko Fukuda; Hiroyuki Marusawa; Makoto Hijikata
Hepatitis C virus and its roles in cell proliferation.
Journal of gastroenterology 2002;37 Suppl 13():50-4.
2001: Hiroyuki Marusawa; S Imoto; Y Ueda; Tsutomu Chiba
Reactivation of latently infected hepatitis B virus in a leukemia patient with antibodies to hepatitis B core antigen.
Journal of gastroenterology 2001;36(9):633-6.
2001: N Pathan; Hiroyuki Marusawa; Maryla Krajewska; Shu-ichi Matsuzawa; H Kim; K Okada; S Torii; Shinichi Kitada; Stan Krajewski; Kate Welsh; frederic pio; Adam Godzik; John C Reed
TUCAN, an antiapoptotic caspase-associated recruitment domain family protein overexpressed in cancer.
The Journal of biological chemistry 2001;276(34):32220-9.
2001: Koichi Watashi; Makoto Hijikata; Hiroyuki Marusawa; Takahiro Doi; Kunitada Shimotohno
Cytoplasmic localization is important for transcription factor nuclear factor-kappa B activation by hepatitis C virus core protein through its amino terminal region.
Virology 2001;286(2):391-402.
2001: Hiroyuki Marusawa; Makoto Hijikata; Koichi Watashi; Tsutomu Chiba; Kunitada Shimotohno
Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte derived cell lines.
Microbiology and immunology 2001;45(6):483-9.
2000: Hiroyuki Marusawa; Shinji Uemoto; Makoto Hijikata; Y Ueda; Kiyoji Tanaka; Kunitada Shimotohno; Tsutomu Chiba
Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen.
Hepatology (Baltimore, Md.) 2000;31(2):488-95.
2000: Kazuya Iwai; Masaro Tashima; Mitsuru Itoh; Toshiro Okazaki; Kokichi Yamamoto; Hitoshi Ohno; Hiroyuki Marusawa; Y Ueda; Takefumi Nakamura; Tsutomu Chiba; Takashi Uchiyama
Fulminant hepatitis B following bone marrow transplantation in an HBsAg-negative, HBsAb-positive recipient; reactivation of dormant virus during the immunosuppressive period.
Bone marrow transplantation 2000;25(1):105-8.
1999: Makoto Hijikata; Katsuya Tsuchihara; Hiroyuki Marusawa; Kunitada Shimotohno
[Regulation of cell proliferation by hepatitis C virus].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(11):1543-51.
1999: Hiroyuki Marusawa; Y Osaki; T Kimura; K Ito; Y Yamashita; T Eguchi; Masatoshi Kudo; Y Yamamoto; H Kojima; Hiroshi Seno; F Moriyasu; Tsutomu Chiba
High prevalence of anti-hepatitis B virus serological markers in patients with hepatitis C virus related chronic liver disease in Japan.
Gut 1999;45(2):284-8.
1999: Hiroyuki Marusawa; Makoto Hijikata; Tsutomu Chiba; Kunitada Shimotohno
Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation.
Journal of virology 1999;73(6):4713-20.
1998: Shinji Uemoto; K Sugiyama; Hiroyuki Marusawa; Yukihiro Inomata; Katsuhiro Asonuma; Hiroto Egawa; Tetsuya Kiuchi; Y Miyake; Kiyoji Tanaka; Tsutomu Chiba
Transmission of hepatitis B virus from hepatitis B core antibody-positive donors in living related liver transplants.
Transplantation 1998;65(4):494-9.