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Ikuro Maruyama

Research Profile

Chemicals & Drugs

Living Beings

Rats
Mouse

Anatomy

Physiology

Blood Coagulation

Procedures

Immunohistochemistry

Disorders

Disseminated Intravascular Coagulation

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Publications

TOP 3
Naoki Miura; Noriaki Miyoshi; Tomoka Nagasato; Hisayo Shameshima; Akihide Tanimoto; Tomonobu Yamada; Takashi Ito; Hiroyuki Izumi; Hiroaki Kawaguchi; Ikuro Maruyama
Coagulation activity and white thrombus formation in the microminipig.
Kazuya Hosokawa; Takashi Ito; Takehiko Koide; Naoki Miura; Tomoko Ohnishi; Hisayo Sameshima; Ikuro Maruyama
Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions.
Hitoshi Yamahata; Hajime Yonezawa; Shunji Yunoue; Ryosuke Hanaya; Hirofumi Hirano; Prasanna Karki; Ko-ichi Kawahara; Ikuro Maruyama; Sei Sugata; Hiroshi Tokimura; Mai Tokudome; Kazunori Arita
Immunohistochemical expression of thrombomodulin in vestibular schwannoma.

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All Publications

2013: Naoki Miura; Noriaki Miyoshi; Tomoka Nagasato; Hisayo Shameshima; Akihide Tanimoto; Tomonobu Yamada; Takashi Ito; Hiroyuki Izumi; Hiroaki Kawaguchi; Ikuro Maruyama
Coagulation activity and white thrombus formation in the microminipig.
In vivo (Athens, Greece) 2013;27(3):357-61.
2013: Kazuya Hosokawa; Takashi Ito; Takehiko Koide; Naoki Miura; Tomoko Ohnishi; Hisayo Sameshima; Ikuro Maruyama
Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions.
Thrombosis and haemostasis 2013;109(1):102-11.
2013: Hitoshi Yamahata; Hajime Yonezawa; Shunji Yunoue; Ryosuke Hanaya; Hirofumi Hirano; Prasanna Karki; Ko-ichi Kawahara; Ikuro Maruyama; Sei Sugata; Hiroshi Tokimura; Mai Tokudome; Kazunori Arita
Immunohistochemical expression of thrombomodulin in vestibular schwannoma.
Brain tumor pathology 2013;30(1):28-33.
2012: Yasutaka Oda; Ryosuke Tsuruta; Ikuro Maruyama; Motoki Fujita; Tomonori Izumi; Kotaro Kaneda; Shunji Kasaoka; Yoshikatsu Kawamura; Tsuyoshi Maekawa
Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims: a pilot study.
Resuscitation 2012;83(8):1006-12.
2012: Ikuro Maruyama
[Polyol-, hexosamine pathway and protein C kinase activation in the pathogenesis of diabetic complications].
Nihon rinsho. Japanese journal of clinical medicine 2012;70 Suppl 5():227-30.
2012: Ko-ichi Tada; Teruto Hashiguchi; Ko-ichi Kawahara; Ikuro Maruyama; Shigeto Matsushita; Takuro Kanekura
MK615, a Prunus mume Steb. Et Zucc ('Ume') extract, attenuates the growth of A375 melanoma cells by inhibiting the ERK1/2-Id-1 pathway.
Phytotherapy research : PTR 2012;26(6):833-8.
2012: Masaaki Omichi; Ikuro Maruyama; Michiya Matsusaki; Mitsuru Akashi
Improvement of blood compatibility on polysulfone-polyvinylpyrrolidone blend films as a model membrane of dialyzer by physical adsorption of recombinant soluble human thrombomodulin (ART-123).
Journal of biomaterials science. Polymer edition 2012;23(5):593-608.
2011: Shinsuke Sugiura; Naomi Tanigawa; Hiroki Mizutani; Toshihide Noguchi; Makoto Hagiwara; Yuichi Ishihara; Yoshiko Kato; Ko-ichi Kawahara; Toshinori Komatsu; Ikuro Maruyama; Kenji Matsushita
Valproic acid increases susceptibility to endotoxin shock through enhanced release of high-mobility group box 1.
Shock (Augusta, Ga.) 2011;36(5):494-500.
2011: Narimasa Yoshinaga; Noboru Arimura; Teruto Hashiguchi; Ko-Ichi Kawahara; Ikuro Maruyama; Hiroki Otsuka; Taiji Sakamoto
NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway.
Laboratory investigation; a journal of technical methods and pathology 2011;91(9):1277-90.
2011: Naoko Mizukami; Kunitsugu Takasaki; Nami Ueya; Toshinori Yuasa; Hideto Chaen; Shuichi Hamasaki; Yoshihisa Horizoe; Yutaka Imoto; Akira Kisanuki; Eiji Kuwahara; Ikuro Maruyama; Chuwa Tei
Different flow patterns between left and right internal thoracic artery grafts influence the evaluation of severe graft stenosis by transthoracic Doppler echocardiography.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2011;24(7):768-74.
2011: Ikuro Maruyama
[HMGB1(High mobility group box 1 protein)].
Rinsho byori. The Japanese journal of clinical pathology 2011;Suppl 147():49-55.
2011: Ikuro Maruyama
[New insight in the concept on DIC].
Rinsho byori. The Japanese journal of clinical pathology 2011;Suppl 147():20-4.
2010: Kiyoshi Kikuchi; Ko-ichi Kawahara; Naohisa Miyagi; Hisaaki Uchikado; Terukazu Kuramoto; Yoko Morimoto; Salunya tancharoen; Naoki Miura; Kazunori Takenouchi; Yoko Oyama; Binita Shrestha; Fumiyo Matsuda; Yoshihiro Yoshida; Shin-ichiro Arimura; Kentaro Mera; Ko-ichi Tada; Narimasa Yoshinaga; Ryuichi Maenosono; Yoshiko Ohno; Teruto Hashiguchi; Ikuro Maruyama; Minoru Shigemori
Edaravone: a new therapeutic approach for the treatment of acute stroke.
Medical hypotheses 2010;75(6):583-5.
2010: Hiroki Otsuka; Noboru Arimura; Shozo Sonoda; Makoto Nakamura; Teruto Hashiguchi; Ikuro Maruyama; Shintaro Nakao; Ali Hafezi-Moghadam; Taiji Sakamoto
Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.
The American journal of pathology 2010;177(5):2268-77.
2010: Masaaki Omichi; Michiya Matsusaki; Shinya Kato; Ikuro Maruyama; Mitsuru Akashi
Enhancement of the blood compatibility of dialyzer membranes by the physical adsorption of human thrombomodulin (ART-123).
Journal of biomedical materials research. Part B, Applied biomaterials 2010;95(2):291-7.
2010: Motoki Fujita; Ryosuke Tsuruta; Tadashi Kaneko; Yohei Otsuka; Satoshi Kutsuna; Tomonori Izumi; Tetsuya Aoki; Masaki Shitara; Shunji Kasaoka; Ikuro Maruyama; Makoto Yuasa; Tsuyoshi Maekawa
Hyperoxia suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats: laboratory study.
Shock (Augusta, Ga.) 2010;34(3):299-305.
2010: Ikuro Maruyama
[HMGB1].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 7():137-40.
2010: Kentaro Mera; Ko-ichi Kawahara; Ko-ichi Tada; Kazuhiro Kawai; Teruto Hashiguchi; Ikuro Maruyama; Takuro Kanekura
ER signaling is activated to protect human HaCaT keratinocytes from ER stress induced by environmental doses of UVB.
Biochemical and biophysical research communications 2010;397(2):350-4.
2010: Shotaro Taniguchi; Teruto Hashiguchi; Tomoko Ono; Kazunori Takenouchi; Koujin Nakayama; Takahisa Kawano; Kaori Kato; Ryuji Matsushita; Masanao Nagatomo; Shuji Nakamura; Tomonori Nakashima; Ikuro Maruyama
Association between reduced ADAMTS13 and diabetic nephropathy.
Thrombosis research 2010;125(6):e310-6.
2010: Yoko Oyama; Teruto Hashiguchi; Noboru Taniguchi; Salunya tancharoen; Tomonori Uchimura; Kamal Krishna Biswas; Ko-Ichi Kawahara; Takao Nitanda; Yoshihisa Umekita; Martin Lotz; Ikuro Maruyama
High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy.
Laboratory investigation; a journal of technical methods and pathology 2010;90(6):853-66.
2010: Hideyuki Kawabata; Takao Setoguchi; Kazunori Yone; Masakazu Souda; Hiroki Yoshida; Ko-ichi Kawahara; Ikuro Maruyama; Setsuro Komiya
High mobility group box 1 is upregulated after spinal cord injury and is associated with neuronal cell apoptosis.
Spine 2010;35(11):1109-15.
2010: Sayaka Kozono; T Matsuyama; Kamal Krishna Biwasa; Ko-ichi Kawahara; Yumiko Nakajima; Takehiko Yoshimoto; Yutaka Yonamine; Hideshi Kadomatsu; Salunya tancharoen; Teruto Hashiguchi; Kazuyuki Noguchi; Ikuro Maruyama
Involvement of the endocannabinoid system in periodontal healing.
Biochemical and biophysical research communications 2010;394(4):928-33.
2010: Michiya Matsusaki; Masaaki Omichi; Koji Kadowaki; Bong Hoon Kim; Sang Ouk Kim; Ikuro Maruyama; Mitsuru Akashi
Protein nanoarrays on a highly-oriented lamellar surface.
Chemical communications (Cambridge, England) 2010;46(11):1911-3.
2010: Tetsu Yamamoto; Takashi Ono; Takashi Ito; Akira Yamanoi; Ikuro Maruyama; Tsuneo Tanaka
Hemoperfusion with a high-mobility group box 1 adsorption column can prevent the occurrence of hepatic ischemia-reperfusion injury in rats.
Critical care medicine 2010;38(3):879-85.
2010: Ryosuke Tsuruta; Motoki Fujita; Takeru Ono; Yoichi Koda; Yasutaka Koga; Takahiro Yamamoto; Masahiro Nanba; Masaki Shitara; Shunji Kasaoka; Ikuro Maruyama; Makoto Yuasa; Tsuyoshi Maekawa
Hyperglycemia enhances excessive superoxide anion radical generation, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats.
Brain research 2010;1309():155-63.
2010: Yoshiko Ohno; Teruto Hashiguchi; Ryuichi Maenosono; Hidetoshi Yamashita; Yukio Taira; Kazufumi Minowa; Yoshihito Yamashita; Yuko Kato; Ko-Ichi Kawahara; Ikuro Maruyama
The diagnostic value of endothelial function as a potential sensor of fatigue in health.
Vascular health and risk management 2010;6():135-44.
2010: Kentaro Ueno; Yuichi Nomura; Teruto Hashiguchi; Kiminori Masuda; Yasuko Morita; Daisuke Hazeki; Taisuke Eguchi; Ikuro Maruyama; Yoshifumi Kawano
Platelet vascular endothelial growth factor is a useful predictor for prognosis in Kawasaki syndrome.
British journal of haematology 2010;148(2):285-92.
2010: Hideo Wada; Hidesaku Asakura; Kohji Okamoto; Toshiaki Iba; Toshimasa Uchiyama; Kazuo Kawasugi; Shin Koga; Toshihiko Mayumi; Kaoru Koike; Satoshi Gando; Shigeki Kushimoto; Yoshinobu Seki; Seiji Madoiwa; Ikuro Maruyama; Akira Yoshioka
Expert consensus for the treatment of disseminated intravascular coagulation in Japan.
Thrombosis research 2010;125(1):6-11.
2009: Kiyoshi Kikuchi; Salunya tancharoen; Fumiyo Matsuda; Kamal Krishna Biswas; Takashi Ito; Yoko Morimoto; Yoko Oyama; Kazunori Takenouchi; Naoki Miura; Noboru Arimura; Yuko Nawa; Xiaojie Meng; Binita Shrestha; Shin-ichiro Arimura; Masahiro Iwata; Kentaro Mera; Hisayo Sameshima; Yoshiko Ohno; Ryuichi Maenosono; Yutaka Tajima; Hisaaki Uchikado; Terukazu Kuramoto; Kenji Nakayama; Minoru Shigemori; Yoshihiro Yoshida; Teruto Hashiguchi; Ikuro Maruyama; Ko-Ichi Kawahara
Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4.
Biochemical and biophysical research communications 2009;390(4):1121-5.
2009: Takeru Ono; Ryosuke Tsuruta; Motoki Fujita; Hiromi Shinagawa Aki; Satoshi Kutsuna; Yoshikatsu Kawamura; Jun Wakatsuki; Tetsuya Aoki; Chihiro Kobayashi; Shunji Kasaoka; Ikuro Maruyama; Makoto Yuasa; Tsuyoshi Maekawa
Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion.
Brain research 2009;1305():158-67.
2009: Takashi Nakahara; Ryosuke Tsuruta; Tadashi Kaneko; Susumu Yamashita; Motoki Fujita; Shunji Kasaoka; Teruto Hashiguchi; Michiyasu Suzuki; Ikuro Maruyama; Tsuyoshi Maekawa
High-mobility group box 1 protein in CSF of patients with subarachnoid hemorrhage.
Neurocritical care 2009;11(3):362-8.
2009: Yoko Morimoto; Kiyoshi Kikuchi; Takashi Ito; Masayuki Tokuda; T Matsuyama; Satoshi Noma; Teruto Hashiguchi; Mitsuo Torii; Ikuro Maruyama; Ko-Ichi Kawahara
MK615 attenuates Porphyromonas gingivalis lipopolysaccharide-induced pro-inflammatory cytokine release via MAPK inactivation in murine macrophage-like RAW264.7 cells.
Biochemical and biophysical research communications 2009;389(1):90-4.
2009: Natsumi Araya; Hitoshi Arimura; Ko-ichi Kawahara; Naoko Yagishita; Junji Ishida; Ryoji Fujii; Satoko Aratani; Hidetoshi Fujita; Tomoo Sato; Yoshihisa Yamano; Itsuro Higuchi; Mitsuhiro Osame; Kusuki Nishioka; Akiyoshi Fukamizu; Kimiyoshi Arimura; Ikuro Maruyama; Toshihiro Nakajima
Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase.
International journal of molecular medicine 2009;24(5):605-11.
2009: Teruto Hashiguchi; Kenji Tanaka; Lyang-Ja Lee; Ken Sasaki; Shoji Natsugoe; Ko-Ichi Kawahara; Kimiyoshi Arimura; Ikuro Maruyama
Diagnostic value of serum peptidome analyses for protease activated pathological conditions beyond cancer diagnosis.
Medical hypotheses 2009;73(5):760-3.
2009: Hiromi Shinagawa Aki; Motoki Fujita; Susumu Yamashita; Kenji Fujimoto; Kazumi Kumagai; Ryosuke Tsuruta; Shunji Kasaoka; Tetsuya Aoki; Masahiro Nanba; Hidenori Murata; Makoto Yuasa; Ikuro Maruyama; Tsuyoshi Maekawa
Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats.
Brain research 2009;1292():180-90.
2009: Xiaojie Meng; Ko-ichi Kawahara; Kenji Matsushita; Yuko Nawa; Binita Shrestha; Kiyoshi Kikuchi; Hisayo Sameshima; Teruto Hashiguchi; Ikuro Maruyama
Attenuation of LPS-induced iNOS expression by 1,5-anhydro-d-fructose.
Biochemical and biophysical research communications 2009;387(1):42-6.
2009: Megumi Inomata; Yuichi Ishihara; Takashi Matsuyama; Takahisa Imamura; Ikuro Maruyama; Toshihide Noguchi; Kenji Matsushita
Degradation of vascular endothelial thrombomodulin by arginine- and lysine-specific cysteine proteases from Porphyromonas gingivalis.
Journal of periodontology 2009;80(9):1511-7.
2009: Yuko Nawa; Ko-ichi Kawahara; Salunya tancharoen; Xiaojie Meng; Hisayo Sameshima; Takashi Ito; Yoshiki Masuda; Hitoshi Imaizumi; Teruto Hashiguchi; Ikuro Maruyama
Nucleophosmin may act as an alarmin: implications for severe sepsis.
Journal of leukocyte biology 2009;86(3):645-53.
2009: Kiyoshi Kikuchi; Ko-ichi Kawahara; Kamal Krishna Biswas; Takashi Ito; Salunya tancharoen; Yoko Morimoto; Fumiyo Matsuda; Yoko Oyama; Kazunori Takenouchi; Naoki Miura; Noboru Arimura; Yuko Nawa; Xiaojie Meng; Binita Shrestha; Shin-ichiro Arimura; Masahiro Iwata; Kentaro Mera; Hisayo Sameshima; Yoshiko Ohno; Ryuichi Maenosono; Yoshihiro Yoshida; Yutaka Tajima; Hisaaki Uchikado; Terukazu Kuramoto; Kenji Nakayama; Minoru Shigemori; Teruto Hashiguchi; Ikuro Maruyama
Minocycline attenuates both OGD-induced HMGB1 release and HMGB1-induced cell death in ischemic neuronal injury in PC12 cells.
Biochemical and biophysical research communications 2009;385(2):132-6.
2009: Kiyoshi Kikuchi; Ko-ichi Kawahara; Salunya tancharoen; Fumiyo Matsuda; Yoko Morimoto; Takashi Ito; Kamal Krishna Biswas; Kazunori Takenouchi; Naoki Miura; Yoko Oyama; Yuko Nawa; Noboru Arimura; Masahiro Iwata; Yutaka Tajima; Terukazu Kuramoto; Kenji Nakayama; Minoru Shigemori; Yoshihiro Yoshida; Teruto Hashiguchi; Ikuro Maruyama
The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.
The Journal of pharmacology and experimental therapeutics 2009;329(3):865-74.
2009: Noboru Arimura; Hiroki Otsuka; Keita Yamakiri; Yasushi Sonoda; Shintaro Nakao; Yoshihiro Noda; Teruto Hashiguchi; Ikuro Maruyama; Taiji Sakamoto
Vitreous mediators after intravitreal bevacizumab or triamcinolone acetonide in eyes with proliferative diabetic retinopathy.
Ophthalmology 2009;116(5):921-6.
2009: Ko-Ichi Kawahara; Teruto Hashiguchi; Kazuo Masuda; Abbi R Saniabadi; Kiyoshi Kikuchi; Salunya tancharoen; Takashi Ito; Naoki Miura; Yoko Morimoto; Kamal Krishna Biswas; Yuko Nawa; Xiaojie Meng; Yoko Oyama; Kazunori Takenouchi; Binita Shrestha; Hisayo Sameshima; Toshiaki Shimizu; Taro Adachi; Masakazu Adachi; Ikuro Maruyama
Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc.
International journal of molecular medicine 2009;23(5):615-20.
2009: Taisuke Eguchi; Yuichi Nomura; Teruto Hashiguchi; Kiminori Masuda; Michiko Arata; Daisuke Hazeki; Kentaro Ueno; Junichiro Nishi; Yoshifumi Kawano; Ikuro Maruyama
An elevated value of high mobility group box 1 is a potential marker for poor response to high-dose of intravenous immunoglobulin treatment in patients with Kawasaki syndrome.
The Pediatric infectious disease journal 2009;28(4):339-41.
2009: Xiaojie Meng; Ko-ichi Kawahara; Yuko Nawa; Naoki Miura; Binita Shrestha; Salunya tancharoen; Hisayo Sameshima; Teruto Hashiguchi; Ikuro Maruyama
1,5-Anhydro-D-fructose attenuates lipopolysaccharide-induced cytokine release via suppression of NF-kappaB p65 phosphorylation.
Biochemical and biophysical research communications 2009;380(2):343-8.
2009: Noboru Arimura; Yuya Ki-i; Teruto Hashiguchi; Ko-ichi Kawahara; Kamal K Biswas; Makoto Nakamura; Yasushi Sonoda; Keita Yamakiri; Akiko Okubo; Taiji Sakamoto; Ikuro Maruyama
Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.
Laboratory investigation; a journal of technical methods and pathology 2009;89(3):278-89.
2009: Toshihiko Izumi; Ryoji Fujii; Tomonori Izumi; Minako Nakazawa; Naoko Yagishita; Kaneyuki Tsuchimochi; Yoshihisa Yamano; Tomoo Sato; Hidetoshi Fujita; Satoko Aratani; Natsumi Araya; Kazuko Azakami; Daisuke Hasegawa; Shunji Kasaoka; Ryosuke Tsuruta; Masahiro Yokouti; Kosei Ijiri; Moroe Beppu; Ikuro Maruyama; Kusuki Nishioka; Tsuyoshi Maekawa; Setsuro Komiya; Toshihiro Nakajima
Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.
Arthritis and rheumatism 2009;60(1):63-72.
2008: Masahiro Iwata; Ko-Ichi Kawahara; Hisashi Kawabata; Takashi Ito; Kentaro Mera; Kamal Krishna Biswas; Salunya tancharoen; Yuko Higashi; Kiyoshi Kikuchi; Teruto Hashiguchi; Takuro Kanekura; Ikuro Maruyama
Thrombomodulin exerts cytoprotective effect on low-dose UVB-irradiated HaCaT cells.
Biochemical and biophysical research communications 2008;377(2):642-7.
2008: Nazgul A Omurzakova; Yoshihisa Yamano; Tomoo Sato; Toshihiko Izumi; Kazuko Azakami; Daisuke Hasegawa; Ryoji Fujii; Naoko Yagishita; Satoko Aratani; Zuhra S Kabaeva; Mirsaid M Mirrakhimov; Masahiro Kami; Ikuro Maruyama; Mitsuhiro Osame; Shunpei Yokota; Kusuki Nishioka; Toshihiro Nakajima
Increased prevalence of group A β-hemolytic streptococcus among an ethnic population in Kyrgyzstan detected by the rapid antigen detection test.
Molecular medicine reports 2008;1(6):869-74.
2008: Ko-Ichi Kawahara; Teruto Hashiguchi; Kiyoshi Kikuchi; Salunya tancharoen; Naoki Miura; Takashi Ito; Yoko Oyama; Yuko Nawa; Kamal Krishna Biswas; Xiaojie Meng; Yoko Morimoto; Binita Shrestha; Hisayo Sameshima; Ikuro Maruyama
Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells.
International journal of molecular medicine 2008;22(5):639-44.
2008: Takashi Ito; Ko-ichi Kawahara; Kohji Okamoto; Shingo Yamada; Minetsugu Yasuda; Hitoshi Imaizumi; Yuko Nawa; Xiaojie Meng; Binita Shrestha; Teruto Hashiguchi; Ikuro Maruyama
Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1825-30.
2008: Takashi Hamada; Motofumi Torikai; Ai Kuwazuru; Motoyuki Tanaka; Naoto Horai; Takeo Fukuda; Shingo Yamada; Shinichi Nagayama; Kanehisa Hashiguchi; Nobuhiko Sunahara; Koichiro Fukuzaki; Ryoichi Nagata; Setsuro Komiya; Ikuro Maruyama; Takeo Fukuda; Kazuhiro Abeyama
Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis.
Arthritis and rheumatism 2008;58(9):2675-85.
2008: Noboru Arimura; Yuya Ki-I; Teruto Hashiguchi; Taiji Sakamoto; Ikuro Maruyama
High-mobility group box 1 protein in endophthalmitis.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2008;246(7):1053-8.
2008: Ko-ichi Kawahara; Kamal Krishna Biswas; Masako Unoshima; Takashi Ito; Kiyoshi Kikuchi; Yoko Morimoto; Masahiro Iwata; Salunya tancharoen; Yoko Oyama; Kazunori Takenouchi; Yuko Nawa; Noboru Arimura; Meng Xiao Jie; Binita Shrestha; Naoki Miura; Toshiaki Shimizu; Kentaro Mera; Shin-ichiro Arimura; Noboru Taniguchi; Hideo Iwasaka; Sonshin Takao; Teruto Hashiguchi; Ikuro Maruyama
C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2008;17(3):129-38.
2008: Katsuhiko Ehi; Sumiya Ishigami; Izumi Masamoto; Yoshikazu Uenosono; Shoji Natsugoe; Takaaki Arigami; Hideo Arima; Yuko Kijima; Heiji Yoshinaka; Shigehiro Yanagita; Tsutomu Kozono; Yawara Funasako; Ikuro Maruyama; Takashi Aikou
Analysis of T-helper type 1 and 2 cells and T-cytotoxic type 1 and 2 cells of sentinel lymph nodes in breast cancer.
Oncology reports 2008;19(3):601-7.
2008: Kiyokazu Hiwatashi; Shinichi Ueno; Kazuhiro Abeyama; Fumitake Kubo; Masahiko Sakoda; Ikuro Maruyama; M Hamanoue; Shoji Natsugoe; Takashi Aikou
A novel function of the receptor for advanced glycation end-products (RAGE) in association with tumorigenesis and tumor differentiation of HCC.
Annals of surgical oncology 2008;15(3):923-33.
2008: Y Morimoto; Ko-ichi Kawahara; Salunya tancharoen; K Kikuchi; T Matsuyama; Teruto Hashiguchi; Yuichi Izumi; Ikuro Maruyama
Tumor necrosis factor-alpha stimulates gingival epithelial cells to release high mobility-group box 1.
Journal of periodontal research 2008;43(1):76-83.
2008: Michiya Matsusaki; Masaaki Omichi; Ikuro Maruyama; Mitsuru Akashi
Physical adsorption of human thrombomodulin (ART-123) onto polymeric biomaterials for developing an antithrombogenic blood-contacting material.
Journal of biomedical materials research. Part A 2008;84(1):1-9.
2007: Yuya Ki-I; Noboru Arimura; Yoshihiro Noda; Keita Yamakiri; Norihito Doi; Teruto Hashiguchi; Ikuro Maruyama; Masahiko Shimura; Taiji Sakamoto
Stromal-derived factor-1 and inflammatory cytokines in retinal vein occlusion.
Current eye research 2007;32(12):1065-72.
2007: Ko-ichi Kawahara; Kentaro Setoyama; Kiyoshi Kikuchi; Kamal Krishna Biswas; Ryozo Kamimura; Masahiro Iwata; Takashi Ito; Yoko Morimoto; Teruto Hashiguchi; Sonshin Takao; Ikuro Maruyama
HMGB1 release in co-cultures of porcine endothelial and human T cells.
Xenotransplantation 2007;14(6):636-41.
2007: Kuriko Kimura; Teruto Hashiguchi; Takahisa Deguchi; Shuji Horinouchi; Tadashi Uto; Hiroko Oku; Shiro Setoyama; Ikuro Maruyama; Mitsuhiro Osame; Kimiyoshi Arimura
Serum VEGF--as a prognostic factor of atherosclerosis.
Atherosclerosis 2007;194(1):182-8.
2007: Takashi Kajiya; Ryuichiro Anan; Masahiro Kameko; Naoko Mizukami; Shinichi Minagoe; Shuichi Hamasaki; Ikuro Maruyama; Ryuzo Sakata; Chuwa Tei
Intracardiac thrombus, superior vena cava syndrome, and pulmonary embolism in a patient with Behçet's disease: a case report and literature review.
Heart and vessels 2007;22(4):278-83.
2007: Katsumi Inoue; Ko-ichi Kawahara; Kamal Krishna Biswas; Kenji Ando; Kazuaki Mitsudo; Masakiyo Nobuyoshi; Ikuro Maruyama
HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 2007;16(3):136-43.
2007: Tetsuhiko Taira; Wataru Matsuyama; Hideo Mitsuyama; Ko-ichi Kawahara; Ikkou Higashimoto; Ikuro Maruyama; Mitsuhiro Osame; Kimiyoshi Arimura
Increased serum high mobility group box-1 level in Churg-Strauss syndrome.
Clinical and experimental immunology 2007;148(2):241-7.
2007: Shin-ichiro Arimura; Ko-ichi Kawahara; Kamal Krishna Biswas; Kazuhiro Abeyama; Masashi Tabata; Toru Shimoda; Daisuke Ogomi; Michiya Matsusaki; Shinya Kato; Takashi Ito; Kazumasa Sugihara; Mitsuru Akashi; Teruto Hashiguchi; Ikuro Maruyama
Hydroxyapatite formed on/in agarose gel induces activation of blood coagulation and platelets aggregation.
Journal of biomedical materials research. Part B, Applied biomaterials 2007;81(2):456-61.
2007: Satoshi Noma; Wataru Matsuyama; Hideo Mitsuyama; Takayuki Suetsugu; Yoshimizu Koreeda; Keiko Mizuno; Ikkou Higashimoto; Yasuyuki Kakihana; Teruto Hashiguchi; Ikuro Maruyama; Mitsuhiro Osame; Kimiyoshi Arimura
Two cases of acute exacerbation of interstitial pneumonia treated with polymyxin B-immobilized fiber column hemoperfusion treatment.
Internal medicine (Tokyo, Japan) 2007;46(17):1447-54.
2007: T Ito; Ko-ichi Kawahara; T Nakamura; Shingo Yamada; T Nakamura; Kazuhiro Abeyama; Teruto Hashiguchi; Ikuro Maruyama
High-mobility group box 1 protein promotes development of microvascular thrombosis in rats.
Journal of thrombosis and haemostasis : JTH 2007;5(1):109-16.
2007: Ko-ichi Kawahara; Salunya tancharoen; Teruto Hashiguchi; Masako Unoshima; Takashi Ito; Kiyoshi Kikuchi; Yoko Morimoto; Toshiaki Shimizu; Yoko Oyama; Kazunori Takenouchi; Shin-ichiro Arimura; Noboru Taniguchi; Masahiro Iwata; Hideo Iwasaka; Ikuro Maruyama
Inhibition of HMGB1 by deep ocean water attenuates endotoxin-induced sepsis.
Medical hypotheses 2007;68(6):1429-30.
2006: Takuro Kanekura; Noriko Yoshii; Koichi Kawahara; Ikuro Maruyama; Tamotsu Kanzaki
Granulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2006;10(3):287-90.
2006: Takuro Kanekura; Katsuya Hiraishi; Koichi Kawahara; Ikuro Maruyama; Tamotsu Kanzaki
Granulocyte and monocyte adsorption apheresis (GCAP) for refractory skin diseases caused by activated neutrophils and psoriatic arthritis: evidence that GCAP removes Mac-1-expressing neutrophils.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2006;10(3):247-56.
2006: Kenji Matsushita; Takahisa Imamura; Salunya tancharoen; Syouko Tatsuyama; Munehiro Tomikawa; James Travis; Jan Potempa; Mitsuo Torii; Ikuro Maruyama
Selective inhibition of Porphyromonas gingivalis growth by a factor Xa inhibitor, DX-9065a.
Journal of periodontal research 2006;41(3):171-6.
2006: Kenji Matsushita; Takahisa Imamura; Munehiro Tomikawa; Salunya tancharoen; Syouko Tatsuyama; Ikuro Maruyama
DX-9065a inhibits proinflammatory events induced by gingipains and factor Xa.
Journal of periodontal research 2006;41(2):148-56.
2006: Ikuro Maruyama
[Molecular mechanisms of the therapeutic agents for kidney diseases: Anti-platelets/anti-coagulant medicines].
Nihon rinsho. Japanese journal of clinical medicine 2006;64 Suppl 2():652-6.
2006: Kunihiro Manago; Junichiro Nishi; Naoko Wakimoto; Hiroaki Miyanohara; Jav Sarantuya; Koichi Tokuda; Mayumi Iwashita; Kimie Yamamoto; Masao Yoshinaga; Ikuro Maruyama; Yoshifumi Kawano
Biofilm formation by and accessory gene regulator typing of methicillin-resistant Staphylococcus aureus strains recovered from patients with nosocomial infections.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2006;27(2):188-90.
2006: Kamal Krishna Biswas; Salunya tancharoen; Salunya Tancharon; Krishna Pada Sarker; Ko-ichi Kawahara; Teruto Hashiguchi; Ikuro Maruyama
Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.
FEBS letters 2006;580(2):703-10.
2006: Yumiko Nakajima; Yasushi Furuichi; Kamal Krishna Biswas; Teruto Hashiguchi; Ko-ichi Kawahara; Kazuyo Yamaji-Kegan; Tomonori Uchimura; Yuichi Izumi; Ikuro Maruyama
Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition.
FEBS letters 2006;580(2):613-9.
2005: Ikuro Maruyama
[Recent advances in cerebrovascular diseases from the view point of blood coagulation/fibrinolysis].
Rinshō shinkeigaku = Clinical neurology 2005;45(11):806-7.
2005: Ikuro Maruyama; Shingo Yamada
[HMGB1].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 8():125-7.
2005: Takuro Kanekura; Koichi Kawahara; Ikuro Maruyama; Tamotsu Kanzaki
Treatment of pyoderma gangrenosum with granulocyte and monocyte adsorption apheresis.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 2005;9(4):292-6.
2005: Shinichi Ueno; Dai Aoki; Fumitake Kubo; Kiyokazu Hiwatashi; Kenji Matsushita; Tohru Oyama; Ikuro Maruyama; Takashi Aikou
Roxithromycin inhibits constitutive activation of nuclear factor {kappa}B by diminishing oxidative stress in a rat model of hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5645-50.
2005: Salunya tancharoen; Krishna Pada Sarker; Takahisa Imamura; Kamal Krishna Biswas; Kenji Matsushita; Syouko Tatsuyama; James Travis; Jan Potempa; Mitsuo Torii; Ikuro Maruyama
Neuropeptide release from dental pulp cells by RgpB via proteinase-activated receptor-2 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5796-804.
2005: Kazuhiro Abeyama; David M Stern; Yuji Ito; Ko-ichi Kawahara; Yasushi Yoshimoto; Motoyuki Tanaka; Tomonori Uchimura; Nobuo Ida; Yoshiaki Yamazaki; Shingo Yamada; Yasuhiko Yamamoto; Hiroshi Yamamoto; Satoshi Iino; Noboru Taniguchi; Ikuro Maruyama
The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.
The Journal of clinical investigation 2005;115(5):1267-74.
2005: S Mori; Akira Mizoguchi; Masaharu Kawabata; Hidetomo Fukunaga; Koichiro Usuku; Ikuro Maruyama; Mitsuhiro Osame
Bronchoalveolar lymphocytosis correlates with human T lymphotropic virus type I (HTLV-I) proviral DNA load in HTLV-I carriers.
Thorax 2005;60(2):138-43.
2005: Krishna Pada Sarker; Kamal Krishna Biswas; Kazuyo Yamaji-Kegan; Munekazu Yamakuchi; Teruto Hashiguchi; Ki-Young Lee; Ikuro Maruyama
Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatroban.
Pathophysiology of haemostasis and thrombosis 2005;34(1):41-7.
2005: Dai Aoki; Shinichi Ueno; Fumitake Kubo; Tohru Oyama; Tetsuya Sakuta; Kenji Matsushita; Ikuro Maruyama; Takashi Aikou
Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production.
Anticancer research 2005;25(1A):133-8.
2005: Kazuyo Yamaji-Kegan; Yin Wang; Yan Liu; Kazuhiro Abeyama; Teruto Hashiguchi; Tomonori Uchimura; Kamal Krishna Biswas; Hisahiko Iwamoto; Ikuro Maruyama
Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.
Thrombosis research 2005;115(4):319-25.
2005: Yasue Haraguchi; Masao Yoshinaga; Jav Sarantuya; Atsushi Shimago; Junichiro Nishi; Yukiharu Kono; Yuichi Nomura; Rieko Kubo; Taisuke Eguchi; Satoru Tanaka; Sadamitsu Yanagi; Toshiro Fukushige; Ikuro Maruyama; Yoshifumi Kawano
Interval representative of transmural dispersion of repolarization in children and young adolescents with congenital long QT syndrome.
Circulation journal : official journal of the Japanese Circulation Society 2005;69(1):78-82.
2005: Yoshihiro Motomiya; Yukio Ando; Katsuki Haraoka; Xuguo Sun; Hiroyuki Morita; Izumi Amano; Tomonori Uchimura; Ikuro Maruyama
Studies on unfolded beta-microglobulin at C-terminal in dialysis-related amyloidosis.
Kidney international 2005;67(1):314-20.
2004: Ikuro Maruyama
[t-PA x PAI-1 complex].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 12():714-6.
2004: Ikuro Maruyama
[Prothrombin (factor II) and prothrombin fragment 1+2 (F1+2)].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 12():623-5.
2004: Kazuhiro Abeyama; Ikuro Maruyama
[Inflammation and its regulatory system].
Nihon rinsho. Japanese journal of clinical medicine 2004;62(12):2229-35.
2004: Masahiko Saigo; David D Waters; Satoshi Abe; Sadatoshi Biro; Shinichi Minagoe; Ikuro Maruyama; Chuwa Tei
Soluble fibrin, C-reactive protein, fibrinogen, factor VII, antithrombin, proteins C and S, tissue factor, D-dimer, and prothrombin fragment 1 + 2 in men with acute myocardial infarction
The American journal of cardiology 2004;94(11):1410-3.

2004: Ikuro Maruyama
[Homocysteine].
Nihon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 11():620-2.
2004: Satoshi Iino; Kazuhiro Abeyama; Ko-Ichi Kawahara; Munekazu Yamakuchi; Teruto Hashiguchi; Sumika Matsukita; Suguru Yonezawa; Shotaro Taniguchi; Masanori Nakata; Sonshin Takao; Takashi Aikou; Ikuro Maruyama
The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 1):6179-88.
2004: Takuro Kanekura; Akira Gushi; Masahiro Iwata; Seita Fukumaru; Ryoko Sakamoto; Koichi Kawahara; Ikuro Maruyama; Tamotsu Kanzaki
Treatment of Behçet's disease with granulocyte and monocyte adsorption apheresis.
Journal of the American Academy of Dermatology 2004;51(2 Suppl):S83-7.
2004: Takuro Kanekura; Kenjiro Terasaki; Y Higashi; Noriko Yoshii; Koichi Kawahara; Ikuro Maruyama; Tamotsu Kanzaki
Improvement of adult Still's disease with granulocyte and monocyte adsorption apheresis.
Clinical and experimental dermatology 2004;29(4):410-2.
2004: Takefumi Kasai; Kazuhiro Abeyama; Teruto Hashiguchi; Hidetoshi Fukunaga; Mitsuhiro Osame; Ikuro Maruyama
Decreased total nitric oxide production in patients with duchenne muscular dystrophy.
Journal of biomedical science 2004;11(4):534-7.
2004: Masakazu Ogawa; Satoshi Abe; Sadatoshi Biro; Masahiko Saigo; Takashi Kihara; Shiro Setoyama; Tatsuru Matsuoka; Hitoshi Toda; Hiroyuki Torii; Yoshihiko Atsuchi; Yoshifumi Toyama; Shigeki Tateishi; Shinichi Minagoe; Ikuro Maruyama; Chuwa Tei
R353Q polymorphism, activated factor VII, and risk of premature myocardial infarction in Japanese men.
Circulation journal : official journal of the Japanese Circulation Society 2004;68(6):520-5.
2004: Sumiya Ishigami; Shoji Natsugoe; Futoshi Miyazono; Koki Tokuda; Akihiro Nakajo; Masataka Matsumoto; Hiroshi Okumura; Saburo Nakashima; Shuichi Hokita; Ikuro Maruyama; Takashi Aikou
CD3 zeta expression of regional lymph node and peripheral blood lymphocytes in gastric cancer.
Anticancer research 2004;24(3b):2123-6.
2004: Kazuyo Yamaji-Kegan; Krishna Pada Sarker; Kazuhiro Abeyama; Ikuro Maruyama
Anti-atherogenic effects of an egg yolk-enriched garlic supplement.
International journal of food sciences and nutrition 2004;55(1):61-6.
2004: Takashi Motobe; Teruto Hashiguchi; Tomonori Uchimura; Munekazu Yamakuchi; Noboru Taniguchi; Setsuro Komiya; Ikuro Maruyama
Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome.
Shock (Augusta, Ga.) 2004;21(1):8-12.
2003: Kozue Hasegawa; Yasushi Furuichi; Akihiro Shimotsu; Masahiro Nakamura; Mitsuhiro Yoshinaga; Masato Kamitomo; Masayuki Hatae; Ikuro Maruyama; Yuichi Izumi
Associations between systemic status, periodontal status, serum cytokine levels, and delivery outcomes in pregnant women with a diagnosis of threatened premature labor.
Journal of periodontology 2003;74(12):1764-70.
2003: Takashi Tokashiki; Teruto Hashiguchi; Kimiyoshi Arimura; Nobutaka Eiraku; Ikuro Maruyama; Mitsuhiro Osame
Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.
Internal medicine (Tokyo, Japan) 2003;42(12):1240-3.
2003: Krishna Pada Sarker; Kamal Krishna Biswas; Jesusa L Rosales; Kazuyo Yamaji-Kegan; Teruto Hashiguchi; Ki-Young Lee; Ikuro Maruyama
Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2.
Journal of neurochemistry 2003;87(6):1345-53.
2003: Takayo Arisato; Teruto Hashiguchi; Krishna Pada Sarker; Kimiyoshi Arimura; M Asano; K Matsuo; Mitsuhiro Osame; Ikuro Maruyama
Highly accumulated platelet vascular endothelial growth factor in coagulant thrombotic region.
Journal of thrombosis and haemostasis : JTH 2003;1(12):2589-93.
2003: Yoshihiro Motomiya; Yukio Ando; Katsuki Haraoka; Xuguo Sun; Hisahiko Iwamoto; Tomonori Uchimura; Ikuro Maruyama
Circulating level of alpha2-macroglobulin-beta2-microglobulin complex in hemodialysis patients.
Kidney international 2003;64(6):2244-52.
2003: Kamal Krishna Biswas; Krishna Pada Sarker; Kazuhiro Abeyama; Ko-ichi Kawahara; Satoshi Iino; Yasuharu Otsubo; Kazuhiko Saigo; Hiroyuki Izumi; Teruto Hashiguchi; Munekazu Yamakuchi; Kazuyo Yamaji-Kegan; Ryujin Endo; Kazuyuki Suzuki; Hitoshi Imaizumi; Ikuro Maruyama
Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis.
Hepatology (Baltimore, Md.) 2003;38(5):1167-77.
2003: Kazuhiro Abeyama; Ko-ichi Kawahara; Satoshi Iino; Takashi Hamada; Shin-ichiro Arimura; Kenji Matsushita; Toshihiro Nakajima; Ikuro Maruyama
Antibiotic cyclic AMP signaling by "primed" leukocytes confers anti-inflammatory cytoprotection.
Journal of leukocyte biology 2003;74(5):908-15.
2003: Takayo Arisato; Krishna Pada Sarker; K Kawahara; Masanori Nakata; Teruto Hashiguchi; Mitsuhiro Osame; Isao Kitajima; Ikuro Maruyama
The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells.
Cellular and molecular life sciences : CMLS 2003;60(8):1716-24.
2003: Krishna Pada Sarker; Ikuro Maruyama
Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts.
Cellular and molecular life sciences : CMLS 2003;60(6):1200-8.
2003: Ikuro Maruyama
[Ischemic heart disease and cytokines].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 5():827-30.
2003: Ikuro Maruyama
[Blood coagulation/fibrinolytic system in unstable angina].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 5():206-9.
2003: Kazuyo Yamaji-Kegan; Krishna Pada Sarker; Koichi Kawahara; Satoshi Iino; Munekazu Yamakuchi; Kazuhiro Abeyama; Teruto Hashiguchi; Ikuro Maruyama
Anandamide induces apoptosis in human endothelial cells: its regulation system and clinical implications.
Thrombosis and haemostasis 2003;89(5):875-84.
2003: Ikuro Maruyama
[Coronary thrombosis and coagulation/fibrinolytic system].
Nihon rinsho. Japanese journal of clinical medicine 2003;61 Suppl 4():101-6.
2003: Noboru Taniguchi; Ko-ichi Kawahara; Kazunori Yone; Teruto Hashiguchi; Munekazu Yamakuchi; Masamichi Goto; Keiichi Inoue; Shingo Yamada; Kosei Ijiri; Shunji Matsunaga; Toshihiro Nakajima; Setsuro Komiya; Ikuro Maruyama
High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine.
Arthritis and rheumatism 2003;48(4):971-81.
2003: Krishna Pada Sarker; Kamal Krishna Biswas; Munekazu Yamakuchi; Ki-Young Lee; Teruto Hahiguchi; Michael Kracht; Isao Kitajima; Ikuro Maruyama
ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death.
Journal of neurochemistry 2003;85(1):50-61.
2003: Masakazu Ogawa; Satoshi Abe; Masahiko Saigo; Sadatoshi Biro; Hitoshi Toda; Tatsuru Matsuoka; Hiroyuki Torii; Shinichi Minagoe; Ikuro Maruyama; Chuwa Tei
Homocysteine and hemostatic disorder as a risk factor for myocardial infarction at a young age.
Thrombosis research 2003;109(5-6):253-8.
2002: Soichi Obara; Masanori Nakata; Hideo Takeshima; Jun-ichi Kuratsu; Ikuro Maruyama; Isao Kitajima
Inhibition of migration of human glioblastoma cells by cerivastatin in association with focal adhesion kinase (FAK).
Cancer letters 2002;185(2):153-61.
2002: Junichiro Nishi; Masao Yoshinaga; Hiroaki Miyanohara; Motoshi Kawahara; Masaharu Kawabata; Toshiro Motoya; Tetsuhiro Owaki; Shigeru Oiso; Masayuki Kawakami; Shigeko Kamewari; Yumiko Koyama; Naoko Wakimoto; Koichi Tokuda; Kunihiro Manago; Ikuro Maruyama
An epidemiologic survey of methicillin-resistant Staphylococcus aureus by combined use of mec-HVR genotyping and toxin genotyping in a university hospital in Japan.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2002;23(9):506-10.
2002: Takahito Niiyama; Itsuro Higuchi; Masahito Suehara; Teruto Hashiguchi; Tadafumi Shiraishi; Masanori Nakagawa; Kimiyoshi Arimura; Ikuro Maruyama; Mitsuhiro Osame
Electron microscopic abnormalities of skeletal muscle in patients with collagen VI deficiency in Ullrich's disease.
Acta neuropathologica 2002;104(1):67-71.
2002: Tadahiro Kubo; Masaaki Miyata; Shinichi Minagoe; Shiro Setoyama; Ikuro Maruyama; Chuwa Tei
A simple oscillometric technique for determining new indices of arterial distensibility.
Hypertension research : official journal of the Japanese Society of Hypertension 2002;25(3):351-8.
2002: Hitoshi Yamahata; Hideo Takeshima; Jun-ichi Kuratsu; Krishna Pada Sarker; Koji Tanioka; Naruhito Wakimaru; Masanori Nakata; Isao Kitajima; Ikuro Maruyama
The role of thrombin in the neo-vascularization of malignant gliomas: an intrinsic modulator for the up-regulation of vascular endothelial growth factor.
International journal of oncology 2002;20(5):921-8.
2002: Tomonori Uchimura; Yoshihiro Motomiya; Haruki Okamura; Teruto Hashiguchi; Masakazu Miura; Yoshinori Uji; Hisahiko Iwamoto; Ikuro Maruyama
Marked increases in macrophage colony-stimulating factor and interleukin-18 in maintenance hemodialysis patients: comparative study of advanced glycation end products, carboxymethyllysine and pentosidine.
Nephron 2002;90(4):401-7.
2002: Hisashi Kawabata; Ko-ichi Kawahara; Takuro Kanekura; Natsumi Araya; Hiroaki Daitoku; Mitsutoki Hatta; Naoki Miura; Akiyoshi Fukamizu; Tamotsu Kanzaki; Ikuro Maruyama; Toshihiro Nakajima
Possible role of transcriptional coactivator P/CAF and nuclear acetylation in calcium-induced keratinocyte differentiation.
The Journal of biological chemistry 2002;277(10):8099-105.
2002: Kazuyo Yamaji-Kegan; Krishna Pada Sarker; Ikuro Maruyama; Susumu Hizukuri
Antioxidant effects of 1,5-anhydro-D-fructose, a new natural sugar, in vitro.
Planta medica 2002;68(1):16-9.
2001: Masahiko Saigo; Satoshi Abe; Masakazu Ogawa; T Yamashita; Sadatoshi Biro; Shinichi Minagoe; Ikuro Maruyama; Chuwa Tei
Imbalance of plasminogen activator inhibitor-I/ tissue plasminogen activator and tissue factor/tissue factor pathway inhibitor in young Japanese men with myocardial infarction.
Thrombosis and haemostasis 2001;86(5):1197-203.
2001: Yoshihiro Motomiya; Hisahiko Iwamoto; Yoshinori Uji; T Higashi; Tomonori Uchimura; Ikuro Maruyama
Potential value of CML-Hb in predicting the progression of bone cysts in dialysis-related amyloidosis.
Nephron 2001;89(3):286-90.
2001: Itsuro Higuchi; Tadafumi Shiraishi; Teruto Hashiguchi; Masahito Suehara; Takahito Niiyama; Masanori Nakagawa; Kimiyoshi Arimura; Ikuro Maruyama; Mitsuhiro Osame
Frameshift mutation in the collagen VI gene causes Ullrich's disease.
Annals of neurology 2001;50(2):261-5.
2001: Y Wang; Y Liu; Y Ito; Teruto Hashiguchi; Isao Kitajima; Munekazu Yamakuchi; H Shimizu; S Matsuo; H Imaizumi; Ikuro Maruyama
Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock.
Analytical biochemistry 2001;294(1):73-82.
2001: Y Liu; Y Wang; Munekazu Yamakuchi; S Masuda; T Tokioka; S Yamaoka; Ikuro Maruyama; Isao Kitajima
Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax.
Oncogene 2001;20(20):2514-26.
2001: Tomonori Uchimura; K Nakano; Teruto Hashiguchi; Hisahiko Iwamoto; K Miura; Y Yoshimura; Naohiro Hanyu; K Hirata; M Imakuma; Yoshihiro Motomiya; Ikuro Maruyama
Elevation of N-(carboxymethyl)valine residue in hemoglobin of diabetic patients. Its role in the development of diabetic nephropathy.
Diabetes care 2001;24(5):891-6.
2001: Y Liu; Y Wang; Munekazu Yamakuchi; Sumikazu Isowaki; Etsuro Nagata; Yuichi Kanmura; Isao Kitajima; Ikuro Maruyama
Upregulation of toll-like receptor 2 gene expression in macrophage response to peptidoglycan and high concentration of lipopolysaccharide is involved in NF-kappa b activation.
Infection and immunity 2001;69(5):2788-96.
2001: Tetsuya Sakuta; Kakushi Matsushita; N Yamaguchi; Tohru Oyama; R Motani; T Koga; Shigetaka Nagaoka; Kazuhiro Abeyama; Ikuro Maruyama; Haruhiko Takada; Mitsuo Torii
Enhanced production of vascular endothelial growth factor by human monocytic cells stimulated with endotoxin through transcription factor SP-1.
Journal of medical microbiology 2001;50(3):233-7.
2001: Akio Kishida; T Matsuyama; I Kitajima; Ikuro Maruyama; Mitsuru Akashi
Study of cell-material interaction by estimating NF-kappaB activation in HeLa S3 cells adhered onto hydrophilic substrates.
Biomaterials 2001;22(6):541-6.
2001: Ikuro Maruyama
[Abnormality of coagulation/fibrinolysis in hyperlipidemia].
Nihon rinsho. Japanese journal of clinical medicine 2001;59 Suppl 2():732-5.
2000: A Iguchi; Isao Kitajima; Munekazu Yamakuchi; S Ueno; Takashi Aikou; T Kubo; K Matsushima; N Mukaida; Ikuro Maruyama
PEA3 and AP-1 are required for constitutive IL-8 gene expression in hepatoma cells.
Biochemical and biophysical research communications 2000;279(1):166-71.
2000: Krishna Pada Sarker; M Nakata; Isao Kitajima; T Nakajima; Ikuro Maruyama
Inhibition of caspase-3 activation by SB 203580, p38 mitogen-activated protein kinase inhibitor in nitric oxide-induced apoptosis of PC-12 cells.
Journal of molecular neuroscience : MN 2000;15(3):243-50.
2000: Tohru Oyama; Tetsuya Sakuta; Kakushi Matsushita; Ikuro Maruyama; Shigetaka Nagaoka; Mitsuo Torii
Effects of roxithromycin on tumor necrosis factor-alpha-induced vascular endothelial growth factor expression in human periodontal ligament cells in culture.
Journal of periodontology 2000;71(10):1546-53.
2000: Masahiko Saigo; Satoshi Abe; Masakazu Ogawa; Sadatoshi Biro; Shinichi Minagoe; Ikuro Maruyama; Hitoshi Toda; K Kiyonaga; Yoshihiko Atsuchi; Minoru Tahara; Koshi Mawatari; Chuwa Tei
Plasma level of triglyceride-rich lipoprotein remnants is closely associated with the activation of coagulation factor VII in patients with myocardial infarction.
Thrombosis research 2000;100(1):9-17.
2000: Kakushi Matsushita; R Motani; Tetsuya Sakuta; N Yamaguchi; T Koga; K Matsuo; Shigetaka Nagaoka; Kazuhiro Abeyama; Ikuro Maruyama; Mitsuo Torii
The role of vascular endothelial growth factor in human dental pulp cells: induction of chemotaxis, proliferation, and differentiation and activation of the AP-1-dependent signaling pathway.
Journal of dental research 2000;79(8):1596-603.
2000: Munekazu Yamakuchi; Itsuro Higuchi; S Masuda; Y Ohira; T Kubo; Y Kato; Ikuro Maruyama; Isao Kitajima
Type I muscle atrophy caused by microgravity-induced decrease of myocyte enhancer factor 2C (MEF2C) protein expression.
FEBS letters 2000;477(1-2):135-40.
2000: Teruto Hashiguchi; Kimiyoshi Arimura; K Matsumuro; Reika Otsuka; Osamu Watanabe; Manabu Jonosono; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
Highly concentrated vascular endothelial growth factor in platelets in Crow-Fukase syndrome.
Muscle & nerve 2000;23(7):1051-6.
2000: Junichiro Nishi; Ikuro Maruyama
Increased expression of vascular endothelial growth factor (VEGF) in Castleman's disease: proposed pathomechanism of vascular proliferation in the affected lymph node.
Leukemia & lymphoma 2000;38(3-4):387-94.
2000: T Matsuyama; Yuichi Izumi; K Shibatate; Yukiharu Yotsumoto; H Obama; M Uemura; Ikuro Maruyama; T Sueda
Expression and activity of thrombomodulin in human gingival epithelium: in vivo and in vitro studies.
Journal of periodontal research 2000;35(3):146-57.
2000: Ikuro Maruyama; Masanori Nakata; Kazuyo Yamaji-Kegan
Effect of leptin in platelet and endothelial cells. Obesity and arterial thrombosis.
Annals of the New York Academy of Sciences 2000;902():315-9.
2000: Krishna Pada Sarker; S Obara; M Nakata; Isao Kitajima; Ikuro Maruyama
Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3.
FEBS letters 2000;472(1):39-44.
2000: Y Wang; Y Liu; Krishna Pada Sarker; M Nakashima; T Serizawa; A Kishida; M Akashi; M Nakata; Isao Kitajima; Ikuro Maruyama
Polymyxin B binds to anandamide and inhibits its cytotoxic effect.
FEBS letters 2000;470(2):151-5.
2000: A Kishida; M Nakashima; N Sakamoto; T Serizawa; Ikuro Maruyama; M Akashi
Study on complex formation between recombinant human thrombomodulin fragment and thrombin using surface plasmon resonance.
American journal of hematology 2000;63(3):136-40.
2000: H Ogawa; Suguru Yonezawa; Ikuro Maruyama; Y Matsushita; Y Tezuka; H Toyoyama; M Yanagi; Hitoshi Matsumoto; H Nishijima; T Shimotakahara; Takashi Aikou; Eiichi Sato
Expression of thrombomodulin in squamous cell carcinoma of the lung: its relationship to lymph node metastasis and prognosis of the patients.
Cancer letters 2000;149(1-2):95-103.
2000: Ikuro Maruyama
[Abnormality of red blood cells].
Ryōikibetsu shōkōgun shirīzu 2000;(29 Pt 4):187-90.
2000: S Kato; Akio Kishida; Naohiro Hanyu; Ikuro Maruyama; Mitsuru Akashi
Study of cellular responses to polymeric biomaterials using the differential display method.
Journal of biomaterials science. Polymer edition 2000;11(4):333-40.
1999: K Kawahara; S Watanabe; T Ohshima; Y Soejima; T Oishi; S Aratani; Masanori Nakata; M Shibata; K Inoue; T Amano; R Fujii; K Yanai; M Hagiwara; Akiyoshi Fukamizu; Ikuro Maruyama; Toshihiro Nakajima
Hypernuclear acetylation in atherosclerotic lesions and activated vascular smooth muscle cells.
Biochemical and biophysical research communications 1999;266(2):417-24.
1999: Masanori Nakata; N Uto; Ikuro Maruyama; Toshihiko Yada
Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6.
Cell structure and function 1999;24(6):451-5.
1999: Takahito Niiyama; Itsuro Higuchi; Ikuro Maruyama; Mitsuhiro Osame
Expression of thrombomodulin, caveolin-3, and desmin on muscle fibers in neuromuscular diseases.
Muscle & nerve 1999;22(12):1713-6.
1999: Krishna Pada Sarker; Hitoshi Yamahata; Masanori Nakata; Takayo Arisato; T Nakajima; Isao Kitajima; Ikuro Maruyama
Recombinant thrombomodulin inhibits thrombin-induced vascular endothelial growth factor production in neuronal cells.
Haemostasis 1999;29(6):343-52.
1999: Ikuro Maruyama
[t-PA-PAI-1 complex].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():688-90.
1999: Ikuro Maruyama
[Prothrombin (factor II) and fragment 1+2 (F1+2)].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():579-81.
1999: Krishna Pada Sarker; Kazuhiro Abeyama; Junichiro Nishi; Masanori Nakata; T Tokioka; T Nakajima; Isao Kitajima; Ikuro Maruyama
Inhibition of thrombin-induced neuronal cell death by recombinant thrombomodulin and E5510, a synthetic thrombin receptor signaling inhibitor.
Thrombosis and haemostasis 1999;82(3):1071-7.
1999: Ikuro Maruyama
Recombinant thrombomodulin and activated protein C in the treatment of disseminated intravascular coagulation.
Thrombosis and haemostasis 1999;82(2):718-21.
1999: Ikuro Maruyama
[Homocysteine].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():589-91.
1999: K Nakano; Ikuro Maruyama
[Essential requirement in clinical laboratory system for the development of evidence-based medicine (EBM)].
Nihon rinsho. Japanese journal of clinical medicine 1999;57 Suppl():11-7.
1999: Kakushi Matsushita; R Motani; Tetsuya Sakuta; Shigetaka Nagaoka; Takami Matsuyama; Kazuhiro Abeyama; Ikuro Maruyama; Haruhiko Takada; Mitsuo Torii
Lipopolysaccharide enhances the production of vascular endothelial growth factor by human pulp cells in culture.
Infection and immunity 1999;67(4):1633-9.
1999: H Obama; Kosuke Obama; M Takemoto; Y Soejima; Tsutomu Shirahama; Yasuyo Ohi; H Yoshida; M Qzawa; T Muramatsu; Ikuro Maruyama
Expression of Thrombomodulin in the epithelium of the urinary bladder: a possible source of urinary thrombomodulin.
Anticancer research 1999;19(2A):1143-7.
1999: F Ukaji; Isao Kitajima; T Kubo; C Shimizu; T Nakajima; Ikuro Maruyama
Serum samples of patients with rheumatoid arthritis contain a specific autoantibody to "denatured" aldolase A in the osteoblast-like cell line, MG-63.
Annals of the rheumatic diseases 1999;58(3):169-74.
1999: Junichiro Nishi; Kimiyoshi Arimura; Atae Utsunomiya; S Yonezawa; K Kawakami; Nobuaki Maeno; Osamu Ijichi; Naoaki Ikarimoto; M Nakata; I Kitajima; Toshiro Fukushige; Hideo Takamatsu; Koichiro Miyata; Ikuro Maruyama
Expression of vascular endothelial growth factor in sera and lymph nodes of the plasma cell type of Castleman's disease.
British journal of haematology 1999;104(3):482-5.
1999: M Tabata; Kazumasa Sugihara; R Matsui; Suguru Yonezawa; Kazuhiro Abeyama; Ikuro Maruyama
Angiosarcoma of the tongue: report of a case with immunohistochemical findings.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1999;28(2):92-5.
1999: H Shin; Isao Kitajima; T Nakajima; Q Shao; T Tokioka; I Takasaki; N Hanyu; T Kubo; Ikuro Maruyama
Thrombin receptor mediated signals induce expressions of interleukin 6 and granulocyte colony stimulating factor via NF-kappa B activation in synovial fibroblasts.
Annals of the rheumatic diseases 1999;58(1):55-60.
1998: Kenji Matsushita; T Tajima; K Tomita; Kazuhiro Abeyama; Ikuro Maruyama; Haruhiko Takada; Shigetaka Nagaoka
Inflammatory cytokine production and specific antibody responses against possible causative bacteria in patients with multilesional periapical periodontitis.
Journal of endodontics 1998;24(12):817-21.
1998: K Nakano; Ikuro Maruyama
[Our challenge in Kagoshima University Hospital--development of more useful clinical laboratory].
Rinsho byori. The Japanese journal of clinical pathology 1998;46(11):1089-96.
1998: Osamu Watanabe; Ikuro Maruyama; Kimiyoshi Arimura; Isao Kitajima; H Arimura; M Hanatani; K Matsuo; Takayo Arisato; Mitsuhiro Osame
Overproduction of vascular endothelial growth factor/vascular permeability factor is causative in Crow-Fukase (POEMS) syndrome.
Muscle & nerve 1998;21(11):1390-7.
1998: Ikuro Maruyama
[Coagulation/fibrinolytic system and platelet in acute coronary syndrome].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(10):2488-92.
1998: Yoshihiro Motomiya; N Oyama; Hisahiko Iwamoto; Tomonori Uchimura; Ikuro Maruyama
N epsilon-(carboxymethyl)lysine in blood from maintenance hemodialysis patients may contribute to dialysis-related amyloidosis.
Kidney international 1998;54(4):1357-66.
1998: Y Matsushita; Kiyotaka Yoshiie; Y Imamura; H Ogawa; H Imamura; Sonshin Takao; Suguru Yonezawa; Takashi Aikou; Ikuro Maruyama; Eiichi Sato
A subcloned human esophageal squamous cell carcinoma cell line with low thrombomodulin expression showed increased invasiveness compared with a high thrombomodulin-expressing clone--thrombomodulin as a possible candidate for an adhesion molecule of squamous cell carcinoma.
Cancer letters 1998;127(1-2):195-201.
1998: Masanori Nakata; S Kanekura; Ikuro Maruyama
DX9065a, an Xa inhibitor, inhibits prothrombin-induced A549 lung adenocarcinoma cell proliferation.
Cancer letters 1998;122(1-2):127-33.
1998: Ikuro Maruyama
Biology of endothelium.
Lupus 1998;7 Suppl 2():S41-3.
1997: Isao Kitajima; Naohiro Hanyu; Ko-ichi Kawahara; Y Soejima; T Kubo; R Yamada; Y Kaneda; Ikuro Maruyama
Ribozyme-based gene cleavage approach to chronic arthritis associated with human T cell leukemia virus type I: induction of apoptosis in synoviocytes by ablation of HTLV-I tax protein.
Arthritis and rheumatism 1997;40(12):2118-27.
1997: Munekazu Yamakuchi; Masanori Nakata; K Kawahara; Isao Kitajima; Ikuro Maruyama
New quinolones, ofloxacin and levofloxacin, inhibit telomerase activity in transitional cell carcinoma cell lines.
Cancer letters 1997;119(2):213-9.
1997: Isao Kitajima; Naohiro Hanyu; Y Soejima; R Hirano; S Arahira; S Yamaoka; R Yamada; Ikuro Maruyama; Y Kaneda
Efficient transfer of synthetic ribozymes into cells using hemagglutinating virus of Japan (HVJ)-cationic liposomes. Application for ribozymes that target human t-cell leukemia virus type I tax/rex mRNA.
The Journal of biological chemistry 1997;272(43):27099-106.
1997: M Tabata; Kazumasa Sugihara; Suguru Yonezawa; S Yamashita; Ikuro Maruyama
An immunohistochemical study of thrombomodulin in oral squamous cell carcinoma and its association with invasive and metastatic potential.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1997;26(6):258-64.
1997: Masanori Nakata; Toshihiko Yada; S Nakagawa; Keiko Kobayashi; Ikuro Maruyama
Citrulline-argininosuccinate-arginine cycle coupled to Ca2+-signaling in rat pancreatic beta-cells.
Biochemical and biophysical research communications 1997;235(3):619-24.
1997: Ikuro Maruyama; K Shigeta; H Miyahara; T Nakajima; H Shin; S Ide; I Kitajima
Thrombin activates NF-kappa B through thrombin receptor and results in proliferation of vascular smooth muscle cells: role of thrombin in atherosclerosis and restenosis.
Annals of the New York Academy of Sciences 1997;811():429-36.
1997: K Tezono; Ikuro Maruyama
[Recent advances in laboratory test of blood coagulation/fibrinolysis, and its perspectives].
Nihon rinsho. Japanese journal of clinical medicine 1997;55 Suppl 1():123-8.
1997: Kimiyoshi Arimura; Osamu Watanabe; Isao Kitajima; Masahito Suehara; S Minato; Yoshito Sonoda; Itsuro Higuchi; S Takenaga; Ikuro Maruyama; Mitsuhiro Osame
Antibodies to potassium channels of PC12 in serum of Isaacs' syndrome: Western blot and immunohistochemical studies.
Muscle & nerve 1997;20(3):299-305.
1997: N Sakamoto; Akio Kishida; Ikuro Maruyama; Mitsuru Akashi
The mechanism of anticoagulant activity of a novel heparinoid sulfated glucoside-bearing polymer.
Journal of biomaterials science. Polymer edition 1997;8(7):545-53.
1997: G Yamada; K Sugimura; S Nakamura; M O Yamada; Y Tohno; Ikuro Maruyama; Isao Kitajima; T Minami
Trace element composition and histological analysis of rat bones from the space shuttle.
Life sciences 1997;60(9):635-42.
1997: Junichiro Nishi; S Kanekura; Syuji Takei; I Kitajima; T Nakajima; Rezwanul Wahid; Kiminori Masuda; Masao Yoshinaga; Ikuro Maruyama; Koichiro Miyata
B cell epitope mapping of the bacterial superantigen staphylococcal enterotoxin B: the dominant epitope region recognized by intravenous IgG.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):247-54.
1996: Isao Kitajima; Y Soejima; I Takasaki; H Beppu; T Tokioka; Ikuro Maruyama
Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts.
Bone 1996;19(3):263-70.
1996: I Kitajima; Ichiro Semba; T Noikura; K Kawano; Y Iwashita; I Takasaki; Ikuro Maruyama; Hiroyuki Arikawa; Katsuichiro Inoue; N Shinohara; S Nagaoka; Y Ohira
Vertebral growth disturbance in rapidly growing rats during 14 days of spaceflight.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(1):156-63.
1996: Isao Kitajima; K Kawahara; N Hanyu; H Shin; T Tokioka; Y Soejima; J Tsutsui; Masayuki Ozawa; T Shimayama; Ikuro Maruyama
Enhanced E-cadherin expression and increased calcium-dependent cell-cell adhesion in human T-cell leukemia virus type I Tax-expressing PC12 cells.
Journal of cell science 1996;109 ( Pt 3)():609-17.
1996: S Kanekura; Isao Kitajima; Junichiro Nishi; Masao Yoshinaga; Koichiro Miyata; Ikuro Maruyama
Low shed L-selectin levels in Kawasaki disease with coronary artery lesions: comment on the article by Furukawa et al.
Arthritis and rheumatism 1996;39(3):534.
1996: Isao Kitajima; T Nakajima; T Imamura; I Takasaki; K Kawahara; T Okano; T Tokioka; Y Soejima; Kazuhiro Abeyama; Ikuro Maruyama
Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(2):200-10.
1996: T Furuzono; Akio Kishida; M Yanagi; T Matsumoto; T Kanda; T Nakamura; Takashi Aiko; Ikuro Maruyama; Mitsuru Akashi
Novel functional polymers: poly(dimethylsiloxane)-polyamide multiblock copolymer. V. The interaction between biomolecules and the surface of aramid-silicone resins.
Journal of biomaterials science. Polymer edition 1996;7(10):871-80.
1995: M Tabata; Suguru Yonezawa; Kazumasa Sugihara; S Yamashita; Ikuro Maruyama
The use of thrombomodulin to study epithelial cell differentiation in neoplastic and non-neoplastic oral lesions.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1995;24(10):443-9.
1995: Yasuhiro Ishidou; Isao Kitajima; H Obama; Ikuro Maruyama; F Murata; T Imamura; N Yamada; P ten Dijke; K Miyazono; Takashi Sakou
Enhanced expression of type I receptors for bone morphogenetic proteins during bone formation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(11):1651-9.
1995: M Arai; Satoshi Mochida; Akihiko Ohno; Itsuro Ogata; H Obama; Ikuro Maruyama; Kenji Fujiwara
Blood coagulation equilibrium in rat liver microcirculation as evaluated by endothelial cell thrombomodulin and macrophage tissue factor.
Thrombosis research 1995;80(2):113-23.
1995: Y Tezuka; Suguru Yonezawa; Ikuro Maruyama; Y Matsushita; T Shimizu; H Obama; M Sagara; Kazusada Shirao; Chikara Kusano; Shoji Natsugoe
Expression of thrombomodulin in esophageal squamous cell carcinoma and its relationship to lymph node metastasis.
Cancer research 1995;55(18):4196-200.
1995: H Shin; T Nakajima; Isao Kitajima; K Shigeta; Kazuhiro Abeyama; T Imamura; T Okano; K Kawahara; T Nakamura; Ikuro Maruyama
Thrombin receptor-mediated synovial proliferation in patients with rheumatoid arthritis.
Clinical immunology and immunopathology 1995;76(3 Pt 1):225-33.
1995: Kazuhiro Abeyama; S Oh; K Kawano; T Nakajima; Y Soejima; K Nakano; Ikuro Maruyama
Nonionic contrast agents produce thrombotic effect by inducing adhesion of leukocytes on human endothelium.
Biochemical and biophysical research communications 1995;212(3):776-83.
1995: Akio Kishida; Y Akatsuka; M Yanagi; Takashi Aikou; Ikuro Maruyama; Mitsuru Akashi
In vivo and ex vivo evaluation of the antithrombogenicity of human thrombomodulin immobilized biomaterials.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1995;41(3):M369-74.
1995: Junichiro Nishi; H Miyanohara; T Nakajima; Isao Kitajima; Masao Yoshinaga; Ikuro Maruyama; Koichiro Miyata
Molecular typing of the methicillin resistance determinant (mec) of clinical strains of Staphylococcus based on mec hypervariable region length polymorphisms.
The Journal of laboratory and clinical medicine 1995;126(1):29-35.
1995: Yuji Takebayashi; Katsushi Yamada; Ikuro Maruyama; R Fujii; S Akiyama; Takashi Aikou
The expression of thymidine phosphorylase and thrombomodulin in human colorectal carcinomas.
Cancer letters 1995;92(1):1-7.
1995: Kazuhiro Abeyama; K Kawano; T Nakajima; I Takasaki; Isao Kitajima; Ikuro Maruyama
Interleukin 6 mediated differentiation and rescue of cell redox in PC12 cells exposed to ionizing radiation.
FEBS letters 1995;364(3):298-300.
1995: Takuro Kanekura; Tamotsu Kanzaki; S Kanekura; K Kawahara; T Nakashima; Isao Kitajima; Ikuro Maruyama
p53 gene mutations in skin cancers with underlying disorders.
Journal of dermatological science 1995;9(3):209-14.
1994: Junichiro Nishi; H Miyanohara; T Nakajima; Isao Kitajima; Masao Yoshinaga; Ikuro Maruyama; Koichiro Miyata
[Molecular typing of the methicillin resistance determinant (mec) of clinical strains of Staphylococcus based on mec hypervariable region length polymorphisms].
Rinsho byori. The Japanese journal of clinical pathology 1994;42(12):1227-33.
1994: Satoshi Abe; Ikuro Maruyama; S Arima; H Yamaguchi; H Okino; Shuichi Hamasaki; T Yamashita; K Nomoto; Minoru Tahara; Yoshihiko Atsuchi
Increased heparin-releasable platelet factor 4 and D dimer in patients one month after the onset of acute myocardial infarction: persistent activation of platelets and the coagulation/fibrinolytic system.
International journal of cardiology 1994;47(1 Suppl):S7-12.
1994: M Take; J Tsutsui; H Obama; Masayuki Ozawa; T Nakayama; Ikuro Maruyama; T Arima; Takashi Muramatsu
Identification of nucleolin as a binding protein for midkine (MK) and heparin-binding growth associated molecule (HB-GAM).
Journal of biochemistry 1994;116(5):1063-8.
1994: Akio Kishida; Y Ueno; Ikuro Maruyama; Mitsuru Akashi
Immobilization of human thrombomodulin on biomaterials: evaluation of the activity of immobilized human thrombomodulin.
Biomaterials 1994;15(14):1170-4.
1994: T Nakajima; Isao Kitajima; H Shin; I Takasaki; K Shigeta; Kazuhiro Abeyama; Y Yamashita; T Tokioka; Y Soejima; Ikuro Maruyama
Involvement of NF-kappa B activation in thrombin-induced human vascular smooth muscle cell proliferation.
Biochemical and biophysical research communications 1994;204(2):950-8.
1994: Isao Kitajima; K Kawahara; T Nakajima; Y Soejima; T Matsuyama; Ikuro Maruyama
Nitric oxide-mediated apoptosis in murine mastocytoma.
Biochemical and biophysical research communications 1994;204(1):244-51.
1994: T Nakajima; Isao Kitajima; H Shin; W Matsumoto; Y Soejima; Ikuro Maruyama
E5510 antagonizes thrombin receptor signals by inhibiting NF-kappa B activation.
Biochemical and biophysical research communications 1994;203(2):1181-7.
1994: K Matsumuro; Shuji Izumo; Fujio Umehara; Takayo Arisato; Ikuro Maruyama; Suguru Yonezawa; H Shirahama; Eiichi Sato; Mitsuhiro Osame
Paraneoplastic vasculitic neuropathy: immunohistochemical studies on a biopsied nerve and post-mortem examination.
Journal of internal medicine 1994;236(2):225-30.
1994: Akio Kishida; Y Ueno; N Fukudome; E Yashima; Ikuro Maruyama; Mitsuru Akashi
Immobilization of human thrombomodulin onto poly(ether urethane urea) for developing antithrombogenic blood-contacting materials.
Biomaterials 1994;15(10):848-52.
1994: Ikuro Maruyama
[Markers of coagulation/fibrinolysis in angitis].
Nihon rinsho. Japanese journal of clinical medicine 1994;52(8):2024-8.
1994: Akio Kishida; Y Ueno; Ikuro Maruyama; Mitsuru Akashi
Immobilization of human thrombomodulin onto biomaterials. Comparison of immobilization methods and evaluation of antithrombogenicity.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1994;40(3):M840-5.
1994: Ikuro Maruyama; K Shinmyozu
[Soluble thrombomodulin: as a marker of endothelial injury].
Rinsho byori. The Japanese journal of clinical pathology 1994;42(6):563-8.
1994: T Furuzono; T Nakajima; Isao Kitajima; Mitsuru Akashi; T Kamada; S Setoyama; Ikuro Maruyama
[The diagnosis of a mutation of the insulin receptor by non-radioisotropical RT-PCR-SSCP analysis].
Rinsho byori. The Japanese journal of clinical pathology 1994;42(6):600-4.
1994: Y Maruyama; Ikuro Maruyama; Y Soejima
Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells.
Biochemical and biophysical research communications 1994;199(3):1262-9.
1994: Ikuro Maruyama; K Shigeta
[Regulation of the endothelial function by thrombomodulin and/or thrombin receptor].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1994;35(3):234-7.
1993: Shinji Ijichi; Shuji Izumo; Nobutaka Eiraku; K Machigashira; Ryuji Kubota; Masahiro Nagai; N Ikegami; N Kashio; Fujio Umehara; Ikuro Maruyama
An autoaggressive process against bystander tissues in HTLV-I-infected individuals: a possible pathomechanism of HAM/TSP.
Medical hypotheses 1993;41(6):542-7.
1993: Ikuro Maruyama; Y Maruyama; T Nakajima; Isao Kitajima; Mitsuhiro Osame; J Q Zhao; I S Chen; S Nakai; M Ikeda; Y Yabu-uchi
Vesnarinone inhibits production of HIV-1 in cultured cells.
Biochemical and biophysical research communications 1993;195(3):1264-71.
1993: Wataru Matsumoto; Ikuro Maruyama
[Platelet functions in atherosclerosis].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(8):1993-7.
1993: T Yamashita; Satoshi Abe; S Arima; K Nomoto; M Miyata; Ikuro Maruyama; Hitoshi Toda; H Okino; Yoshihiko Atsuchi; Minoru Tahara
Myocardial infarct size can be estimated from serial plasma myoglobin measurements within 4 hours of reperfusion.
Circulation 1993;87(6):1840-9.
1993: Satoshi Abe; K Nomoto; S Arima; M Miyata; T Yamashita; Ikuro Maruyama; Hitoshi Toda; H Okino; Yoshihiko Atsuchi; Minoru Tahara
Detection of reperfusion 30 and 60 minutes after coronary recanalization by a rapid new assay of creatine kinase isoforms in acute myocardial infarction.
American heart journal 1993;125(3):649-56.
1993: Ryuji Kubota; Toshinobu Fujiyoshi; Shuji Izumo; Shinji Yashiki; Ikuro Maruyama; Mitsuhiro Osame; Shunro Sonoda
Fluctuation of HTLV-I proviral DNA in peripheral blood mononuclear cells of HTLV-I-associated myelopathy.
Journal of neuroimmunology 1993;42(2):147-54.
1993: Satoshi Abe; S Arima; K Nomoto; Ikuro Maruyama; M Miyata; H Yamaguchi; H Okino; T Yamashita; Yoshihiko Atsuchi; Minoru Tahara
Early detection of coronary reperfusion by rapid assessment of plasma myoglobin.
International journal of cardiology 1993;38(1):33-40.
1993: Ikuro Maruyama
[Therapeutic strategy of newly developing medicines for disseminated intravascular coagulation--activated protein C and thrombomodulin].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(1):99-106.
1993: T Furuzono; E Yashima; Akio Kishida; Ikuro Maruyama; T Matsumoto; Mitsuru Akashi
A novel biomaterial: poly(dimethylsiloxane)-polyamide multiblock copolymer I. Synthesis and evaluation of blood compatibility.
Journal of biomaterials science. Polymer edition 1993;5(1-2):89-98.
1992: M Ueyama; Ikuro Maruyama; M Osame; Y Sawada
Marked increase in plasma interleukin-6 in burn patients.
The Journal of laboratory and clinical medicine 1992;120(5):693-8.
1992: Ikuro Maruyama
[Therapeutic evaluation of recombinant thrombomodulin].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(10):2561-7.
1992: Mitsuru Akashi; Ikuro Maruyama; N Fukudome; E Yashima
Immobilization of human thrombomodulin on glass beads and its anticoagulant activity.
Bioconjugate chemistry 1992;3(5):363-5.
1992: Ikuro Maruyama; S Mori; Masaharu Kawabata; Mitsuhiro Osame
[Bronchopneumonopathy in HTLV-1 associated myelopathy (HAM) and non-HAM HTLV-1 carriers].
Nihon Kyōbu Shikkan Gakkai zasshi 1992;30(5):775-9.
1992: K Shinmyozu; N Machigashira; T Itoyama; Ikuro Maruyama; Mitsuhiro Osame
[Markedly elevated serum neopterin levels in patients with hemophagocytic histiocytosis].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1992;33(4):545-7.
1991: K Shinmyozu; Ikuro Maruyama
[Antithrombotic effect of recombinant human thrombomodulin on experimentally induced thrombosis in rats].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1991;32(5):497-503.
1991: F Usuki; H Ohtani; T Okadome; K Shinmyozu; Ikuro Maruyama; T Sakimoto; M Atsuji; Mitsuhiro Osame
Immunocytochemical study on endothelial markers with the cerebral vessel from a patient with familial moyamoya disease.
Thrombosis and haemostasis 1991;65(4):335-8.
1991: F Usuki; Itsuro Higuchi; Y Soejima; M Hattori; Ikuro Maruyama; Mitsuhiro Osame
Human acid maltase-deficient myogenic cell transformation with origin-defective SV40: characterization of a cloned line.
Muscle & nerve 1991;14(3):245-52.
1991: K Shimmyozu; N Machigashira; T Itoyama; Mitsutoshi Tara; Ikuro Maruyama; Mitsuhiro Osame
[Plasma concentrations of plasminogen activator inhibitor 2 in patients with hematological malignancies and their clinical significance].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1991;32(2):173-5.
1991: Ikuro Maruyama; Y Soejima; Mitsuhiro Osame; T Ito; K Ogawa; S Yamamoto; W A Dittman; H Saito
Increased expression of thrombomodulin on the cultured human umbilical vein endothelial cells and mouse hemangioma cells by cyclic AMP.
Thrombosis research 1991;61(3):301-10.
1991: K Shinmyozu; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame; Mitsutoshi Tara
[A study on the frequency of von Willebrand factor deficiency state].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1991;32(1):67-8.
1991: Shinji Ijichi; M Mishima; Takemasa Matsuda; T Izumihara; K Kojima; T Niimura; Ikuro Maruyama; Mitsuhiro Osame
Concentration of activated T lymphocytes in extracorporeal blood circulation for plasma separation.
Journal of clinical apheresis 1991;6(2):88-9.
1991: Satoshi Abe; S Arima; H Yamaguchi; Yoshihiko Atsuchi; Minoru Tahara; Shoichiro Nakao; H Tanaka; Ikuro Maruyama; K Nomoto; M Ueno
[Non-invasive evaluation of coronary reperfusion using myoglobin: significance of quantitative and semi-quantitative latex agglutination methods].
Journal of cardiology 1991;21(4):847-55.
1990: K Shinmyozu; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
[A family with von Willebrand disease and hypofibrinogenemia].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(9):1463-7.
1990: Shinji Ijichi; Takemasa Matsuda; Ikuro Maruyama; T Izumihara; K Kojima; T Niimura; Y Maruyama; Shunro Sonoda; A Yoshida; Mitsuhiro Osame
Arthritis in a human T lymphotropic virus type I (HTLV-I) carrier.
Annals of the rheumatic diseases 1990;49(9):718-21.
1990: K Shimmyozu; Mitsutoshi Tara; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
[Pure red cell aplasia with monoclonal gammopathy and von Willebrand disease].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(9):1468-73.
1990: T Ijichi; Ikuro Maruyama; S Mori; M Nomoto; Mitsuhiro Osame
[Two cases of HTLV-I associated myelopathy (HAM) complicated with Sjögren's syndrome, T-lymphocyte alveolitis and arthropathy].
Rinshō shinkeigaku = Clinical neurology 1990;30(7):765-70.
1990: K Shimmyozu; N Kadokura; T Itoyama; Mitsutoshi Tara; Ikuro Maruyama; Mitsuhiro Osame
[Increase of serum acidic isoferritins in patients with hemophagocytic histiocytosis].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(7):1036-7.
1990: K Shimmyozu; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame; Mitsutoshi Tara
[Fetal survival after the corticosteroid and low-dose aspirin regimen in a case of anti-phospholipid antibody syndrome].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(7):1034-5.
1990: Ikuro Maruyama
[Synthetic anticoagulant].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(6):776-81.
1990: K Shimmyozu; N Kadokura; Mitsutoshi Tara; Ikuro Maruyama; Mitsuhiro Osame
[Effects of danazol on plasma levels of protein S C4b-binding protein].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(6):860-1.
1990: K Shinmyozu; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame; Mitsutoshi Tara
[Occurrence of subdural hematoma closely associated with danazol administration in a patient with refractory ITP].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(5):674-5.
1990: K Shinmyozu; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
[Occurrence of hemophilia A and von Willebrand disease in the same family].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(5):665-8.
1990: K Shinmyozu; M Kuriyama; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
[Collagen adhesion-aggregation abnormality (2nd report)--congenital platelet membrane glycoprotein VI deficiency].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(5):660-4.
1990: K Shimmyozu; T Okadome; Y Maruyama; N Kadokura; Ikuro Maruyama; Mitsuhiro Osame; Mitsutoshi Tara
[Clinical characteristics of anti-phospholipid antibodies].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(5):633-8.
1990: K Shinmyozu; Mitsutoshi Tara; T Okadome; Y Maruyama; Ikuro Maruyama; Mitsuhiro Osame
[Coincidental occurrence of idiopathic thrombocytopenic purpura in a patient with familial von Willebrand disease].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(4):443-7.
1990: Shinji Ijichi; Y Sano; F Une; Ikuro Maruyama; Mitsuhiro Osame
[Accessory use of protease-inhibiting agents for disease remission in a patient with autoimmune hemolytic anemia associated with B-CLL].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(2):219-23.
1990: K Shimmyozu; N Kadokura; T Itoyama; Mitsutoshi Tara; Ikuro Maruyama; Mitsuhiro Osame
[Peculiar increase of plasma plasminogen activator inhibitor 1 levels in patients with hemophagocytic histiocytosis].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1990;31(1):127-8.
1990: Satoshi Abe; Ikuro Maruyama; S Arima; H Yamaguchi; H Okino; Shuichi Hamasaki; K Nomoto; Yoshihiko Atsuchi; Minoru Tahara; H Tanaka
[Platelet activation during thrombolysis and percutaneous transluminal coronary angioplasty in the acute phase of myocardial infarction].
Journal of cardiology 1990;20(4):849-59.
1989: Shinji Ijichi; Nobutaka Eiraku; Mitsuhiro Osame; Shuji Izumo; Ryuji Kubota; Ikuro Maruyama; M Matsumoto; T Niimura; Shunro Sonoda
Activated T lymphocytes in cerebrospinal fluid of patients with HTLV-I-associated myelopathy (HAM/TSP).
Journal of neuroimmunology 1989;25(2-3):251-4.
1989: I Kitajima; Ikuro Maruyama; Y Maruyama; Shinji Ijichi; Nobutaka Eiraku; Y Mimura; M Osame
Polyarthritis in human T lymphotropic virus type I-associated myelopathy.
Arthritis and rheumatism 1989;32(10):1342-4.
1989: Isao Kitajima; Ikuro Maruyama; H Matsubara; Mitsuhiro Osame; A Igata
Immune dysfunction in hypophosphatemic vitamin D-resistant rickets: immunoregulatory reaction of 1 alpha(OH) vitamin D3.
Clinical immunology and immunopathology 1989;53(1):24-31.
1989: Shinji Ijichi; Nobutaka Eiraku; Mitsuhiro Osame; Shuji Izumo; Ryuji Kubota; Ikuro Maruyama; M Matsumoto; Shunro Sonoda
In vitro modulation of lymphocyte proliferation by prednisolone and interferon-alpha in patients with HTLV-I-associated myelopathy (HAM).
Journal of neuroimmunology 1989;23(2):175-8.
1989: Norio Ohba; M Matsumoto; Munefumi Sameshima; Y Kabayama; Kumiko Nakao; Kazuhiko Unoki; Fumiyuki Uehara; K Kawano; Ikuro Maruyama; Mitsuhiro Osame
Ocular manifestations in patients infected with human T-lymphotropic virus type I.
Japanese journal of ophthalmology 1989;33(1):1-12.
1988: Suguru Yonezawa; Ikuro Maruyama; S Tanaka; T Nakamura; Eiichi Sato
Immunohistochemical localization of thrombomodulin in chorionic diseases of the uterus and choriocarcinoma of the stomach. A comparative study with the distribution of human chorionic gonadotropin.
Cancer 1988;62(3):569-76.
1987: Suguru Yonezawa; Ikuro Maruyama; K Sakae; A Igata; P W Majerus; Eiichi Sato
Thrombomodulin as a marker for vascular tumors. Comparative study with factor VIII and Ulex europaeus I lectin.
American journal of clinical pathology 1987;88(4):405-11.
1983: K Shinmyozu; T Okadome; Ikuro Maruyama; A Igata
[Abdominal aortic aneurysm associated with chronic consumption coagulopathy and cerebral hemorrhage].
[Rinshō ketsueki] The Japanese journal of clinical hematology 1983;24(11):1521-7.

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