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Peter Marynen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Van Loo Peter; Marynen Peter
Computational methods for the detection of cis-regulatory modules.
Düwel Michael; Welteke Verena; Oeckinghaus Andrea; Baens Mathijs; Kloo Bernhard; Ferch Uta; Darnay Bryant G; Ruland Jürgen; Marynen Peter; Krappmann Daniel
A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.
Bossuyt Wouter; De Geest Natalie; Aerts Stein; Leenaerts Iris; Marynen Peter; Hassan Bassem A
The atonal proneural transcription factor links differentiation and tumor formation in Drosophila.

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All Publications

2009: Van Loo Peter; Marynen Peter
Computational methods for the detection of cis-regulatory modules.
Briefings in bioinformatics 2009;10(5):509-24.
2009: Düwel Michael; Welteke Verena; Oeckinghaus Andrea; Baens Mathijs; Kloo Bernhard; Ferch Uta; Darnay Bryant G; Ruland Jürgen; Marynen Peter; Krappmann Daniel
A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7718-28.
2009: Bossuyt Wouter; De Geest Natalie; Aerts Stein; Leenaerts Iris; Marynen Peter; Hassan Bassem A
The atonal proneural transcription factor links differentiation and tumor formation in Drosophila.
PLoS biology 2009;7(2):e40.
2009: Bossuyt Wouter; Kazanjian Avedis; De Geest Natalie; Van Kelst Sofie; De Hertogh Gert; Geboes Karel; Boivin Greg P; Luciani Judith; Fuks Francois; Chuah Marinee; VandenDriessche Thierry; Marynen Peter; Cools Jan; Shroyer Noah F; Hassan Bassem A
Atonal homolog 1 is a tumor suppressor gene.
PLoS biology 2009;7(2):e39.
2009: Noels Heidi; Somers Riet; Liu Hongxiang; Ye Hongtao; Du Ming-Qing; De Wolf-Peeters Christiane; Marynen Peter; Baens Mathijs
Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.
PloS one 2009;4(3):e4822.
2009: Lehnert Stefan; Van Loo Peter; Thilakarathne Pushpike J; Marynen Peter; Verbeke Geert; Schuit Frans C
Evidence for co-evolution between human microRNAs and Alu-repeats.
PloS one 2009;4(2):e4456.
2008: Bousquet Marina; Quelen Cathy; Rosati Roberto; Mansat-De Mas Véronique; La Starza Roberta; Bastard Christian; Lippert Eric; Talmant Pascaline; Lafage-Pochitaloff Marina; Leroux Dominique; Gervais Carine; Viguié Franck; Lai Jean-Luc; Terre Christine; Beverlo Berna; Sambani Costantina; Hagemeijer Anne; Marynen Peter; Delsol Georges; Dastugue Nicole; Mecucci Cristina; Brousset Pierre
Myeloid cell differentiation arrest by miR-125b-1 in myelodysplastic syndrome and acute myeloid leukemia with the t(2;11)(p21;q23) translocation.
The Journal of experimental medicine 2008;205(11):2499-506.
2008: Dewaele Barbara; Wasag Bartosz; Cools Jan; Sciot Raf; Prenen Hans; Vandenberghe Peter; Wozniak Agnieszka; Schöffski Patrick; Marynen Peter; Debiec-Rychter Maria
Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5749-58.
2008: Frints Suzanna Gerarda Maria; Lenzner Steffen; Bauters Mareike; Jensen Lars Riff; Van Esch Hilde; des Portes Vincent; Moog Ute; Macville Merryn Victor Erik; van Roozendaal Kees; Schrander-Stumpel Constance Theresia Rimbertha Maria; Tzschach Andreas; Marynen Peter; Fryns Jean-Pierre; Hamel Ben; van Bokhoven Hans; Chelly Jamel; Beldjord Chérif; Turner Gillian; Gecz Jozef; Moraine Claude; Raynaud Martine; Ropers Hans Hilger; Froyen Guy; Kuss Andreas Walter
MCT8 mutation analysis and identification of the first female with Allan-Herndon-Dudley syndrome due to loss of MCT8 expression.
European journal of human genetics : EJHG 2008;16(9):1029-37.
2008: De Keersmaecker Kim; Rocnik Jennifer L; Bernad Rafael; Lee Benjamin H; Leeman Dena; Gielen Olga; Verachtert Hanne; Folens Cedric; Munck Sebastian; Marynen Peter; Fornerod Maarten; Gilliland D Gary; Cools Jan
Kinase activation and transformation by NUP214-ABL1 is dependent on the context of the nuclear pore.
Molecular cell 2008;31(1):134-42.
2008: Bauters Marijke; Van Esch Hilde; Friez Michael J; Boespflug-Tanguy Odile; Zenker Martin; Vianna-Morgante Angela M; Rosenberg Carla; Ignatius Jaakko; Raynaud Martine; Hollanders Karen; Govaerts Karen; Vandenreijt Kris; Niel Florence; Blanc Pierre; Stevenson Roger E; Fryns Jean-Pierre; Marynen Peter; Schwartz Charles E; Froyen Guy
Nonrecurrent MECP2 duplications mediated by genomic architecture-driven DNA breaks and break-induced replication repair.
Genome research 2008;18(6):847-58.
2008: De Keersmaecker Kim; Lahortiga Idoya; Mentens Nicole; Folens Cedric; Van Neste Leander; Bekaert Sofie; Vandenberghe Peter; Odero Maria D; Marynen Peter; Cools Jan
In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
Haematologica 2008;93(4):533-42.
2008: Coornaert Beatrice; Baens Mathijs; Heyninck Karen; Bekaert Tine; Haegman Mira; Staal Jens; Sun Lijun; Chen Zhijian J; Marynen Peter; Beyaert Rudi
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20.
Nature immunology 2008;9(3):263-71.
2008: Lahortiga Idoya; Akin Cem; Cools Jan; Wilson Todd M; Mentens Nicole; Arthur Diane C; Maric Irina; Noel Pierre; Kocabas Can; Marynen Peter; Lessin Lawrence S; Wlodarska Iwona; Robyn Jamie; Metcalfe Dean D
Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion.
Haematologica 2008;93(1):49-56.
2008: Bauters M; Weuts A; Vandewalle J; Nevelsteen J; Marynen P; Van Esch H; Froyen G
Detection and validation of copy number variation in X-linked mental retardation.
Cytogenetic and genome research 2008;123(1-4):44-53.
2007: Froyen Guy; Van Esch Hilde; Bauters Marijke; Hollanders Karen; Frints Suzanna G M; Vermeesch Joris R; Devriendt Koen; Fryns Jean-Pierre; Marynen Peter
Detection of genomic copy number changes in patients with idiopathic mental retardation by high-resolution X-array-CGH: important role for increased gene dosage of XLMR genes.
Human mutation 2007;28(10):1034-42.
2007: Brems Hilde; Chmara Magdalena; Sahbatou Mourad; Denayer Ellen; Taniguchi Koji; Kato Reiko; Somers Riet; Messiaen Ludwine; De Schepper Sofie; Fryns Jean-Pierre; Cools Jan; Marynen Peter; Thomas Gilles; Yoshimura Akihiko; Legius Eric
Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.
Nature genetics 2007;39(9):1120-6.
2007: Pospisilova H; Baens M; Michaux L; Stul M; Van Hummelen P; Van Loo P; Vermeesch J; Jarosova M; Zemanova Z; Michalova K; Van den Berghe I; Alexander H D; Hagemeijer A; Vandenberghe P; Cools J; De Wolf-Peeters C; Marynen P; Wlodarska I
Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(9):2079-83.
2007: Crescenzi Barbara; La Starza Roberta; Nozzoli Chiara; Ciolli Stefania; Matteucci Caterina; Romoli Silvia; Rigacci Luigi; Gorello Paolo; Bosi Alberto; Martelli Massimo F; Marynen Peter; Mecucci Cristina
Molecular cytogenetic findings in a four-way t(1;12;5;12)(p36;p13;q33;q24) underlying the ETV6-PDGFRB fusion gene in chronic myelomonocytic leukemia.
Cancer genetics and cytogenetics 2007;176(1):67-71.
2007: Froyen Guy; Bauters Marijke; Boyle Jackie; Van Esch Hilde; Govaerts Karen; van Bokhoven Hans; Ropers Hans-Hilger; Moraine Claude; Chelly Jamel; Fryns Jean-Pierre; Marynen Peter; Gecz Jozef; Turner Gillian
Loss of SLC38A5 and FTSJ1 at Xp11.23 in three brothers with non-syndromic mental retardation due to a microdeletion in an unstable genomic region.
Human genetics 2007;121(5):539-47.
2007: Lahortiga Idoya; De Keersmaecker Kim; Van Vlierberghe Pieter; Graux Carlos; Cauwelier Barbara; Lambert Frederic; Mentens Nicole; Beverloo H Berna; Pieters Rob; Speleman Frank; Odero Maria D; Bauters Marijke; Froyen Guy; Marynen Peter; Vandenberghe Peter; Wlodarska Iwona; Meijerink Jules P P; Cools Jan
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.
Nature genetics 2007;39(5):593-5.
2007: La Starza R; Rosati R; Roti G; Gorello P; Bardi A; Crescenzi B; Pierini V; Calabrese O; Baens M; Folens C; Cools J; Marynen P; Martelli M F; Mecucci C; Cuneo A
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(4):830-3.
2007: Noels Heidi; van Loo Geert; Hagens Sofie; Broeckx Vicky; Beyaert Rudi; Marynen Peter; Baens Mathijs
A Novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappaB activation by API2middle dotMALT1 fusions.
The Journal of biological chemistry 2007;282(14):10180-9.
2007: Crescenzi B; Chase A; Starza R La; Beacci D; Rosti V; Gallì A; Specchia G; Martelli M F; Vandenberghe P; Cools J; Jones A V; Cross N C P; Marynen P; Mecucci C
FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(3):397-402.
2007: Lierman Els; Lahortiga Idoya; Van Miegroet Helen; Mentens Nicole; Marynen Peter; Cools Jan
The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.
Haematologica 2007;92(1):27-34.
2006: Sagaert Xavier; Theys Tom; De Wolf-Peeters Christiane; Marynen Peter; Baens Mathijs
Splenic marginal zone lymphoma-like features in API2-MALT1 transgenic mice that are exposed to antigenic stimulation.
Haematologica 2006;91(12):1693-6.
2006: Raedt Thomas De; Stephens Matthew; Heyns Ine; Brems Hilde; Thijs Daisy; Messiaen Ludwine; Stephens Karen; Lazaro Conxi; Wimmer Katharina; Kehrer-Sawatzki Hildegard; Vidaud Dominique; Kluwe Lan; Marynen Peter; Legius Eric
Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion.
Nature genetics 2006;38(12):1419-23.
2006: de Raedt Thomas; Cools Jan; Debiec-Rychter Maria; Brems Hilde; Mentens Nicole; Sciot Raf; Himpens Jacques; de Wever Ivo; Schöffski Patrick; Marynen Peter; Legius Eric
Intestinal neurofibromatosis is a subtype of familial GIST and results from a dominant activating mutation in PDGFRA.
Gastroenterology 2006;131(6):1907-12.
2006: De Keersmaecker K; Lahortiga I; Graux C; Marynen P; Maertens J; Cools J; Vandenberghe P
Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(12):2202-4.
2006: Froyen Guy; Bauters Marijke; Voet Thierry; Marynen Peter
X-linked mental retardation and epigenetics.
Journal of cellular and molecular medicine 2006;10(4):808-25.
2006: Murga Penas Eva M; Kawadler Holli; Siebert Reiner; Frank Matthias; Ye Hongtao; Hinz Kristina; Becher Claudia; Hummel Michael; Barth Thomas F E; Bokemeyer Carsten; Stein Harald; Trümper Lorenz; Möller Peter; Marynen Peter; Du Ming-Qing; Yang Xiaolu; Hansmann Martin L; Dierlamm Judith
A novel fusion of the MALT1 gene and the microtubule-associated protein 4 (MAP4) gene occurs in diffuse large B-cell lymphoma.
Genes, chromosomes & cancer 2006;45(9):863-73.
2006: Lierman Els; Folens Cedric; Stover Elizabeth H; Mentens Nicole; Van Miegroet Helen; Scheers Werner; Boogaerts Marc; Vandenberghe Peter; Marynen Peter; Cools Jan
Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.
Blood 2006;108(4):1374-6.
2006: Menten B; Maas N; Thienpont B; Buysse K; Vandesompele J; Melotte C; de Ravel T; Van Vooren S; Balikova I; Backx L; Janssens S; De Paepe A; De Moor B; Moreau Y; Marynen P; Fryns J-P; Mortier G; Devriendt K; Speleman F; Vermeesch J R
Emerging patterns of cryptic chromosomal imbalance in patients with idiopathic mental retardation and multiple congenital anomalies: a new series of 140 patients and review of published reports.
Journal of medical genetics 2006;43(8):625-33.
2006: Janssen Hilde; Wlodarska Iwona; Mecucci Cristina; Hagemeijer Anne; Vandenberghe Peter; Marynen Peter; Cools Jan
Fusion of ETV6 to GOT1 in a case with myelodysplastic syndrome and t(10;12)(q24;p13).
Haematologica 2006;91(7):949-51.
2006: La Starza R; Aventin A; Matteucci C; Crescenzi B; Romoli S; Testoni N; Pierini V; Ciolli S; Sambani C; Locasciulli A; Di Bona E; Lafage-Pochitaloff M; Martelli M F; Marynen P; Mecucci C
Genomic gain at 6p21: a new cryptic molecular rearrangement in secondary myelodysplastic syndrome and acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2006;20(6):958-64.
2006: Baens Mathijs; Fevery Sabine; Sagaert Xavier; Noels Heidi; Hagens Sofie; Broeckx Vicky; Billiau An D; De Wolf-Peeters Christiane; Marynen Peter
Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitination.
Cancer research 2006;66(10):5270-7.
2006: Stover Elizabeth H; Chen Jing; Folens Cedric; Lee Benjamin H; Mentens Nicole; Marynen Peter; Williams Ifor R; Gilliland D Gary; Cools Jan
Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8078-83.
2006: Aerts Stein; Lambrechts Diether; Maity Sunit; Van Loo Peter; Coessens Bert; De Smet Frederik; Tranchevent Leon-Charles; De Moor Bart; Marynen Peter; Hassan Bassem; Carmeliet Peter; Moreau Yves
Gene prioritization through genomic data fusion.
Nature biotechnology 2006;24(5):537-44.
2006: Prenen Hans; Cools Jan; Mentens Nicole; Folens Cedric; Sciot Raf; Schöffski Patrick; Van Oosterom Allan; Marynen Peter; Debiec-Rychter Maria
Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2622-7.
2006: Janssen Hilde; Marynen Peter
Interaction partners for human ZNF384/CIZ/NMP4--zyxin as a mediator for p130CAS signaling?
Experimental cell research 2006;312(7):1194-204.
2006: Hu Shimin; Du Ming-Qing; Park Sun-Mi; Alcivar Allison; Qu Like; Gupta Sanjeev; Tang Jun; Baens Mathijs; Ye Hongtao; Lee Tae H; Marynen Peter; Riley James L; Yang Xiaolu
cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas.
The Journal of clinical investigation 2006;116(1):174-81.
2006: Baens Mathijs; Noels Heidi; Broeckx Vicky; Hagens Sofie; Fevery Sabine; Billiau An D; Vankelecom Hugo; Marynen Peter
The dark side of EGFP: defective polyubiquitination.
PloS one 2006;1():e54.
2005: Van Esch Hilde; Bauters Marijke; Ignatius Jaakko; Jansen Mieke; Raynaud Martine; Hollanders Karen; Lugtenberg Dorien; Bienvenu Thierry; Jensen Lars Riff; Gecz Jozef; Moraine Claude; Marynen Peter; Fryns Jean-Pierre; Froyen Guy
Duplication of the MECP2 region is a frequent cause of severe mental retardation and progressive neurological symptoms in males.
American journal of human genetics 2005;77(3):442-53.
2005: La Starza R; Aventin A; Crescenzi B; Gorello P; Specchia G; Cuneo A; Angioni A; Bilhou-Nabera C; Boqué C; Foà R; Uyttebroeck A; Talmant P; Cimino G; Martelli M F; Marynen P; Mecucci C; Hagemeijer A
CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(9):1696-9.
2005: De Keersmaecker Kim; Marynen Peter; Cools Jan
Genetic insights in the pathogenesis of T-cell acute lymphoblastic leukemia.
Haematologica 2005;90(8):1116-27.
2005: Wlodarska I; Veyt E; De Paepe P; Vandenberghe P; Nooijen P; Theate I; Michaux L; Sagaert X; Marynen P; Hagemeijer A; De Wolf-Peeters C
FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(8):1299-305.
2005: Bauters Marijke; Van Esch Hilde; Marynen Peter; Froyen Guy
X chromosome array-CGH for the identification of novel X-linked mental retardation genes.
European journal of medical genetics 2005;48(3):263-75.
2005: Van Esch Hilde; Hollanders Karen; Badisco Liesbeth; Melotte Cindy; Van Hummelen Paul; Vermeesch Joris Robert; Devriendt Koen; Fryns Jean-Pierre; Marynen Peter; Froyen Guy
Deletion of VCX-A due to NAHR plays a major role in the occurrence of mental retardation in patients with X-linked ichthyosis.
Human molecular genetics 2005;14(13):1795-803.
2005: Cools Jan; Maertens Chantal; Marynen Peter
Resistance to tyrosine kinase inhibitors: calling on extra forces.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2005;8(3):119-29.
2005: De Keersmaecker Kim; Graux Carlos; Odero Maria D; Mentens Nicole; Somers Riet; Maertens Johan; Wlodarska Iwona; Vandenberghe Peter; Hagemeijer Anne; Marynen Peter; Cools Jan
Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).
Blood 2005;105(12):4849-52.
2005: La Starza Roberta; Specchia Giorgina; Cuneo Antonio; Beacci Donatella; Nozzoli Chiara; Luciano Luigiana; Aventin Anna; Sambani Constantina; Testoni Nicoletta; Foppoli Marco; Invernizzi Rosangela; Marynen Peter; Martelli Massimo F; Mecucci Cristina
The hypereosinophilic syndrome: fluorescence in situ hybridization detects the del(4)(q12)-FIP1L1/PDGFRA but not genomic rearrangements of other tyrosine kinases.
Haematologica 2005;90(5):596-601.
2005: Levine Ross L; Wadleigh Martha; Cools Jan; Ebert Benjamin L; Wernig Gerlinde; Huntly Brian J P; Boggon Titus J; Wlodarska Iwona; Clark Jennifer J; Moore Sandra; Adelsperger Jennifer; Koo Sumin; Lee Jeffrey C; Gabriel Stacey; Mercher Thomas; D'Andrea Alan; Fröhling Stefan; Döhner Konstanze; Marynen Peter; Vandenberghe Peter; Mesa Ruben A; Tefferi Ayalew; Griffin James D; Eck Michael J; Sellers William R; Meyerson Matthew; Golub Todd R; Lee Stephanie J; Gilliland D Gary
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Cancer cell 2005;7(4):387-97.
2005: Corveleyn Anniek; Wlodarska Iwona; Mecucci Cristina; Marynen Peter
The der(12)t(12;16) breakpoint in an acute leukaemia case targets a Sec7 domain containing protein.
International journal of oncology 2005;26(4):1111-20.
2005: Corveleyn Anniek; Janssen Hilde; Martini Alessandra; Somers Riet; Cools Jan; Marynen Peter
Cellular transformation of NIH3T3 fibroblasts by CIZ/NMP4 fusions.
Journal of cellular biochemistry 2005;94(6):1112-25.
2005: Vermeesch Joris R; Melotte Cindy; Froyen Guy; Van Vooren Steven; Dutta Binita; Maas Nicole; Vermeulen Stefan; Menten Björn; Speleman Frank; De Moor Bart; Van Hummelen Paul; Marynen Peter; Fryns Jean-Pierre; Devriendt Koen
Molecular karyotyping: array CGH quality criteria for constitutional genetic diagnosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):413-22.
2005: Speleman F; Cauwelier B; Dastugue N; Cools J; Verhasselt B; Poppe B; Van Roy N; Vandesompele J; Graux C; Uyttebroeck A; Boogaerts M; De Moerloose B; Benoit Y; Selleslag D; Billiet J; Robert A; Huguet F; Vandenberghe P; De Paepe A; Marynen P; Hagemeijer A
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(3):358-66.
2005: Debiec-Rychter Maria; Cools Jan; Dumez Herlinde; Sciot Raf; Stul Michel; Mentens Nicole; Vranckx Hilde; Wasag Bartosz; Prenen Hans; Roesel Johannes; Hagemeijer Anne; Van Oosterom Allan; Marynen Peter
Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants.
Gastroenterology 2005;128(2):270-9.
2005: Michaux L; Wlodarska I; Rack K; Stul M; Criel A; Maerevoet M; Marichal S; Demuynck H; Mineur P; Kargar Samani K; Van Hoof A; Ferrant A; Marynen P; Hagemeijer A
Translocation t(1;6)(p35.3;p25.2): a new recurrent aberration in "unmutated" B-CLL.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(1):77-82.
2004: Graux C; Cools J; Melotte C; Quentmeier H; Ferrando A; Levine R; Vermeesch J R; Stul M; Dutta B; Boeckx N; Bosly A; Heimann P; Uyttebroeck A; Mentens N; Somers R; MacLeod R A F; Drexler H G; Look A T; Gilliland D G; Michaux L; Vandenberghe P; Wlodarska I; Marynen Peter; Hagemeijer Anne
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
Nature genetics 2004;36(10):1084-9.
2004: Cools Jan; Mentens Nicole; Furet Pascal; Fabbro Doriano; Clark Jennifer J; Griffin James D; Marynen Peter; Gilliland D Gary
Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia.
Cancer research 2004;64(18):6385-9.
2004: Van Buggenhout G; Melotte C; Dutta B; Froyen G; Van Hummelen P; Marynen P; Matthijs G; de Ravel T; Devriendt K; Fryns J P; Vermeesch J R
Mild Wolf-Hirschhorn syndrome: micro-array CGH analysis of atypical 4p16.3 deletions enables refinement of the genotype-phenotype map.
Journal of medical genetics 2004;41(9):691-8.
2004: De Raedt Thomas; Brems Hilde; Lopez-Correa Catalina; Vermeesch Joris Robert; Marynen Peter; Legius Eric
Genomic organization and evolution of the NF1 microdeletion region.
Genomics 2004;84(2):346-60.
2004: Vandenberghe P; Wlodarska I; Michaux L; Zachée P; Boogaerts M; Vanstraelen D; Herregods M-C; Van Hoof A; Selleslag D; Roufosse F; Maerevoet M; Verhoef G; Cools J; Gilliland D G; Hagemeijer A; Marynen P
Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(4):734-42.
2004: Cools Jan; Quentmeier Hilmar; Huntly Brian J P; Marynen Peter; Griffin James D; Drexler Hans G; Gilliland D Gary
The EOL-1 cell line as an in vitro model for the study of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia.
Blood 2004;103(7):2802-5.
2004: Crescenzi Barbara; La Starza Roberta; Romoli Silvia; Beacci Donatella; Matteucci Caterina; Barba Gianluca; Aventin Ana; Marynen Peter; Ciolli Stefania; Nozzoli Chiara; Martelli Massimo Fabrizio; Mecucci Cristina
Submicroscopic deletions in 5q- associated malignancies.
Haematologica 2004;89(3):281-5.
2004: Cools Jan; Stover Elizabeth H; Wlodarska Iwona; Marynen Peter; Gilliland D Gary
The FIP1L1-PDGFRalpha kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia.
Current opinion in hematology 2004;11(1):51-7.
2004: Gilliland Gary; Cools Jan; Stover Elizabeth H; Wlodarska Iwona; Marynen Peter
FIP1L1-PDGFRalpha in hypereosinophilic syndrome and mastocytosis.
The hematology journal : the official journal of the European Haematology Association / EHA 2004;5 Suppl 3():S133-7.
2003: Voet Thierry; Schoenmakers Erik; Carpentier Sebastien; Labaere Charlotte; Marynen Peter
Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector.
Genomics 2003;82(6):596-605.
2003: Murga Penas E M; Hinz K; Röser K; Copie-Bergman C; Wlodarska I; Marynen P; Hagemeijer A; Gaulard P; Löning T; Hossfeld D K; Dierlamm J
Translocations t(11;18)(q21;q21) and t(14;18)(q32;q21) are the main chromosomal abnormalities involving MLT/MALT1 in MALT lymphomas.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2003;17(11):2225-9.
2003: Hoornaert Inge; Marynen Peter; Goris Jozef; Sciot Raf; Baens Mathijs
MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL-induced transformation.
Oncogene 2003;22(49):7728-36.
2003: Debiec-Rychter Maria; Marynen Peter; Hagemeijer Anne; Pauwels Patrick
ALK-ATIC fusion in urinary bladder inflammatory myofibroblastic tumor.
Genes, chromosomes & cancer 2003;38(2):187-90.
2003: De Paepe Pascale; Baens Mathijs; van Krieken Han; Verhasselt Bruno; Stul Michel; Simons Annet; Poppe Bruce; Laureys Geneviève; Brons Paul; Vandenberghe Peter; Speleman Frank; Praet Marleen; De Wolf-Peeters Chris; Marynen Peter; Wlodarska Iwona
ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma.
Blood 2003;102(7):2638-41.
2003: Voet Thierry; Liebe Bodo; Labaere Charlotte; Marynen Peter; Scherthan Harry
Telomere-independent homologue pairing and checkpoint escape of accessory ring chromosomes in male mouse meiosis.
The Journal of cell biology 2003;162(5):795-807.
2003: Debiec-Rychter Maria; Croes Romaric; De Vos Rita; Marynen Peter; Roskams Tania; Hagemeijer Anne; Lombaerts Rita; Sciot Raf
Complex genomic rearrangement of ALK loci associated with integrated human Epstein-Barr virus in a post-transplant myogenic liver tumor.
The American journal of pathology 2003;163(3):913-22.
2003: Frints Suzanna G M; Marynen Peter; Hartmann Dieter; Fryns Jean-Pierre; Steyaert Jean; Schachner Melitta; Rolf Bettina; Craessaerts Katleen; Snellinx An; Hollanders Karen; D'Hooge Rudi; De Deyn Peter P; Froyen Guy
CALL interrupted in a patient with non-specific mental retardation: gene dosage-dependent alteration of murine brain development and behavior.
Human molecular genetics 2003;12(13):1463-74.
2003: Frints Suzanna G M; Jun Lin; Fryns Jean-Pierre; Devriendt Koen; Teulingkx Rudi; Van den Berghe Lut; De Vos Bernice; Borghgraef Martine; Chelly Jamel; Des Portes Vincent; Van Bokhoven Hans; Hamel Ben; Ropers Hans-Hilger; Kalscheuer Vera; Raynaud Martine; Moraine Claude; Marynen Peter; Froyen Guy
Inv(X)(p21.1;q22.1) in a man with mental retardation, short stature, general muscle wasting, and facial dysmorphism: clinical study and mutation analysis of the NXF5 gene.
American journal of medical genetics. Part A 2003;119A(3):367-74.
2003: Sanchez-Izquierdo Dolors; Buchonnet Gerard; Siebert Reiner; Gascoyne Randy D; Climent Joan; Karran Loraine; Marin Miguel; Blesa David; Horsman Douglas; Rosenwald Andreas; Staudt Louis M; Albertson Donna G; Du Ming-Qing; Ye Hongtao; Marynen Peter; Garcia-Conde Javier; Pinkel Daniel; Dyer Martin J S; Martinez-Climent Jose Angel
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.
Blood 2003;101(11):4539-46.
2003: Cools Jan; Stover Elizabeth H; Boulton Christina L; Gotlib Jason; Legare Robert D; Amaral Sonia M; Curley David P; Duclos Nicole; Rowan Rebecca; Kutok Jeffery L; Lee Benjamin H; Williams Ifor R; Coutre Steven E; Stone Richard M; DeAngelo Daniel J; Marynen Peter; Manley Paul W; Meyer Thomas; Fabbro Doriano; Neuberg Donna; Weisberg Ellen; Griffin James D; Gilliland D Gary
PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRalpha-induced myeloproliferative disease.
Cancer cell 2003;3(5):459-69.
2003: Murga Penas Eva Maria; Cools Jan; Algenstaedt Petra; Hinz Kristina; Seeger Doris; Schafhausen Philippe; Schilling Georgia; Marynen Peter; Hossfeld Dieter K; Dierlamm Judith
A novel cryptic translocation t(12;17)(p13;p12-p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene.
Genes, chromosomes & cancer 2003;37(1):79-83.
2003: Cools Jan; DeAngelo Daniel J; Gotlib Jason; Stover Elizabeth H; Legare Robert D; Cortes Jorges; Kutok Jeffrey; Clark Jennifer; Galinsky Ilene; Griffin James D; Cross Nicholas C P; Tefferi Ayalew; Malone James; Alam Rafeul; Schrier Stanley L; Schmid Janet; Rose Michal; Vandenberghe Peter; Verhoef Gregor; Boogaerts Marc; Wlodarska Iwona; Kantarjian Hagop; Marynen Peter; Coutre Steven E; Stone Richard; Gilliland D Gary
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.
The New England journal of medicine 2003;348(13):1201-14.
2003: Longo I; Frints S G M; Fryns J-P; Meloni I; Pescucci C; Ariani F; Borghgraef M; Raynaud M; Marynen P; Schwartz C; Renieri A; Froyen G
A third MRX family (MRX68) is the result of mutation in the long chain fatty acid-CoA ligase 4 (FACL4) gene: proposal of a rapid enzymatic assay for screening mentally retarded patients.
Journal of medical genetics 2003;40(1):11-7.
2003: Vermeesch J R; Duhamel H; Raeymaekers P; Van Zand K; Verhasselt P; Fryns J P; Marynen P
A physical map of the chromosome 12 centromere.
Cytogenetic and genome research 2003;103(1-2):63-73.
2002: Frints S G M; Froyen G; Marynen P; Fryns J-P
X-linked mental retardation: vanishing boundaries between non-specific (MRX) and syndromic (MRXS) forms.
Clinical genetics 2002;62(6):423-32.
2002: Frints Suzanna G M; Froyen Guy; Marynen Peter; Willekens Diane; Legius Eric; Fryns Jean-Pierre
Re-evaluation of MRX36 family after discovery of an ARX gene mutation reveals mild neurological features of Partington syndrome.
American journal of medical genetics 2002;112(4):427-8.
2002: Frints Suzanna G M; Borghgraef Martine; Froyen Guy; Marynen Peter; Fryns Jean-Pierre
Clinical study and haplotype analysis in two brothers with Partington syndrome.
American journal of medical genetics 2002;112(4):361-8.
2002: Martini Alessandra; La Starza Roberta; Janssen Hilde; Bilhou-Nabera Chrystèle; Corveleyn Anniek; Somers Riet; Aventin Ana; Foà Robin; Hagemeijer Anne; Mecucci Christina; Marynen Peter
Recurrent rearrangement of the Ewing's sarcoma gene, EWSR1, or its homologue, TAF15, with the transcription factor CIZ/NMP4 in acute leukemia.
Cancer research 2002;62(19):5408-12.
2002: Dierlamm J; Murga Penas E M; Daibata M; Tagushi H; Hinz K; Baens M; Cools J; Schilling G; Michaux L; Marynen P; Miyoshi I; Hossfeld D K
The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(9):1863-4.
2002: Cools Jan; Wlodarska Iwona; Somers Riet; Mentens Nicole; Pedeutour Florence; Maes Brigitte; De Wolf-Peeters Christiane; Pauwels Patrick; Hagemeijer Anne; Marynen Peter
Identification of novel fusion partners of ALK, the anaplastic lymphoma kinase, in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor.
Genes, chromosomes & cancer 2002;34(4):354-62.
2002: Matteucci Caterina; La Starza Roberta; Crescenzi Barbara; Falzetti Daniela; Romoli Silvia; Emiliani Carla; Orlacchio Aldo; Marynen Peter; Martelli Massimo F; Mecucci Cristina
Interpretation of the complex karyotype and identification of a new 6p amplicon by integrated comparative genomic hybridization and fluorescence in situ hybridization on the U937-I cell line.
Cancer genetics and cytogenetics 2002;135(1):28-34.
2002: Cools Jan; Mentens Nicole; Odero Maria D; Peeters Pieter; Wlodarska Iwona; Delforge Michel; Hagemeijer Anne; Marynen Peter
Evidence for position effects as a variant ETV6-mediated leukemogenic mechanism in myeloid leukemias with a t(4;12)(q11-q12;p13) or t(5;12)(q31;p13).
Blood 2002;99(5):1776-84.
2002: La Starza Roberta; Testoni Nicoletta; Lafage-Pochitaloff Marina; Ruggeri Deborah; Ottaviani Emanuela; Perla Gianni; Martelli Massimo Fabrizio; Marynen Peter; Mecucci Cristina
Complex variant Philadelphia translocations involving the short arm of chromosome 6 in chronic myeloid leukemia.
Haematologica 2002;87(2):143-7.
2001: Veugelers M; De Cat B; Delande N; Esselens C; Bonk I; Vermeesch J; Marynen P; Fryns J P; David G
A 4-Mb BAC/PAC contig and complete genomic structure of the GPC5/GPC6 gene cluster on chromosome 13q32.
Matrix biology : journal of the International Society for Matrix Biology 2001;20(5-6):375-85.
2001: Jun L; Frints S; Duhamel H; Herold A; Abad-Rodrigues J; Dotti C; Izaurralde E; Marynen P; Froyen G
NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.
Current biology : CB 2001;11(18):1381-91.
2001: López-Correa C; Dorschner M; Brems H; Lázaro C; Clementi M; Upadhyaya M; Dooijes D; Moog U; Kehrer-Sawatzki H; Rutkowski J L; Fryns J P; Marynen P; Stephens K; Legius E
Recombination hotspot in NF1 microdeletion patients.
Human molecular genetics 2001;10(13):1387-92.
2001: Frints S G; Fryns J; Lagae L; Syrrou M; Marynen P; Devriendt K
Xp22.3; Yq11.2 chromosome translocation and its clinical manifestations.
Annales de génétique 2001;44(2):71-6.
2001: Cools J; Mentens N; Marynen P
A new family of small, palmitoylated, membrane-associated proteins, characterized by the presence of a cysteine-rich hydrophobic motif.
FEBS letters 2001;492(3):204-9.
2001: Van Limbergen H; Beverloo H B; van Drunen E; Janssens A; Hählen K; Poppe B; Van Roy N; Marynen P; De Paepe A; Slater R; Speleman F
Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia.
Genes, chromosomes & cancer 2001;30(3):274-82.
2001: Voet T; Vermeesch J; Carens A; Dürr J; Labaere C; Duhamel H; David G; Marynen P
Efficient male and female germline transmission of a human chromosomal vector in mice.
Genome research 2001;11(1):124-36.
2000: Baens M; Steyls A; Dierlamm J; De Wolf-Peeters C; Marynen P
Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type.
Genes, chromosomes & cancer 2000;29(4):281-91.
2000: Dierlamm J; Baens M; Stefanova-Ouzounova M; Hinz K; Wlodarska I; Maes B; Steyls A; Driessen A; Verhoef G; Gaulard P; Hagemeijer A; Hossfeld D K; De Wolf-Peeters C; Marynen P
Detection of t(11;18)(q21;q21) by interphase fluorescence in situ hybridization using API2 and MLT specific probes.
Blood 2000;96(6):2215-8.
2000: Vogels A; Devriendt K; Vermeesch J R; Van Dael R; Marynen P; Dewaele P; Hageman J; Holvoet M; Fryns J P
Cryptic translocation t(5;18) in familial mental retardation.
Annales de génétique 2000;43(3-4):117-23.
2000: López Correa C; Brems H; Lázaro C; Marynen P; Legius E
Unequal meiotic crossover: a frequent cause of NF1 microdeletions.
American journal of human genetics 2000;66(6):1969-74.
2000: Maes B; Baens M; Marynen P; De Wolf-Peeters C
The product of the t(11;18), an API2-MLT fusion, is an almost exclusive finding in marginal zone cell lymphoma of extranodal MALT-type.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(5):521-6.
2000: Baens M; Maes B; Steyls A; Geboes K; Marynen P; De Wolf-Peeters C
The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation.
The American journal of pathology 2000;156(4):1433-9.
2000: Falzetti D; Vermeesch J R; Matteucci C; Ciolli S; Martelli M F; Marynen P; Mecucci C
Microdissection and FISH investigations in acute myeloid leukemia: a step forward to full identification of complex karyotypic changes.
Cancer genetics and cytogenetics 2000;118(1):28-34.
1999: Vermeesch J R; Duhamel H; Petit P; Falzetti D; Fryns J P; Marynen P
Multiple small accessory marker chromosomes from different centromeric origin in a moderately mentally retarded male.
Human genetics 1999;105(6):611-8.
1999: La Starza R; Stella M; Testoni N; Di Bona E; Ciolli S; Marynen P; Martelli M F; Mandelli F; Mecucci C
Characterization of 12p molecular events outside ETV6 in complex karyotypes of acute myeloid malignancies.
British journal of haematology 1999;107(2):340-6.
1999: Veugelers M; De Cat B; Ceulemans H; Bruystens A M; Coomans C; Dürr J; Vermeesch J; Marynen P; David G
Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans.
The Journal of biological chemistry 1999;274(38):26968-77.
1999: Cools J; Bilhou-Nabera C; Wlodarska I; Cabrol C; Talmant P; Bernard P; Hagemeijer A; Marynen P
Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13).
Blood 1999;94(5):1820-4.
1999: Carrié A; Jun L; Bienvenu T; Vinet M C; McDonell N; Couvert P; Zemni R; Cardona A; Van Buggenhout G; Frints S; Hamel B; Moraine C; Ropers H H; Strom T; Howell G R; Whittaker A; Ross M T; Kahn A; Fryns J P; Beldjord C; Marynen P; Chelly J
A new member of the IL-1 receptor family highly expressed in hippocampus and involved in X-linked mental retardation.
Nature genetics 1999;23(1):25-31.
1999: Carrié A; Nepotes V; Billuart P; Beldjord C; Bienvenu T; Chelly J; Bruls T; Heilig R; Weissenbach J; Jun L; Marynen P
Construction of a highly annotated cosmid contig spanning 550Kb within the X-linked nonspecific mental retardation candidate region at Xp21.3-22.1.
American journal of medical genetics 1999;85(3):252-4.
1999: Dierlamm J; Baens M; Wlodarska I; Stefanova-Ouzounova M; Hernandez J M; Hossfeld D K; De Wolf-Peeters C; Hagemeijer A; Van den Berghe H; Marynen P
The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas.
Blood 1999;93(11):3601-9.
1999: Falzetti D; Vermeesch J R; Hood T L; Nacheva E P; Matteucci C; Martelli M F; Van den Berghe H; Marynen P; Mecucci C
Identification of multiple copies of a 20q-chromosome in a case of myelodysplastic syndrome: a FISH study.
Leukemia research 1999;23(4):407-13.
1999: Devriendt K; Matthijs G; Van Dael R; Gewillig M; Eyskens B; Hjalgrim H; Dolmer B; McGaughran J; Bröndum-Nielsen K; Marynen P; Fryns J P; Vermeesch J R
Delineation of the critical deletion region for congenital heart defects, on chromosome 8p23.1.
American journal of human genetics 1999;64(4):1119-26.
1999: Baens M; Wlodarska I; Corveleyn A; Hoornaert I; Hagemeijer A; Marynen P
A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).
Genomics 1999;56(1):40-50.
1999: Lopez Correa C; Brems H; Lázaro C; Estivill X; Clementi M; Mason S; Rutkowski J L; Marynen P; Legius E
Molecular studies in 20 submicroscopic neurofibromatosis type 1 gene deletions.
Human mutation 1999;14(5):387-93.
1999: Cools J; Peeters P; Voet T; Aventin A; Mecucci C; Grandchamp B; Marynen P
Genomic organization of human JAK2 and mutation analysis of its JH2-domain in leukemia.
Cytogenetics and cell genetics 1999;85(3-4):260-6.
1998: Veugelers M; Vermeesch J; Watanabe K; Yamaguchi Y; Marynen P; David G
GPC4, the gene for human K-glypican, flanks GPC3 on xq26: deletion of the GPC3-GPC4 gene cluster in one family with Simpson-Golabi-Behmel syndrome.
Genomics 1998;53(1):1-11.
1998: Ding H; Beckers M C; Plaisance S; Marynen P; Collen D; Belayew A
Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3 kb dispersed repeated elements.
Human molecular genetics 1998;7(11):1681-94.
1998: Schwaller J; Frantsve J; Aster J; Williams I R; Tomasson M H; Ross T S; Peeters P; Van Rompaey L; Van Etten R A; Ilaria R; Marynen P; Gilliland D G
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes.
The EMBO journal 1998;17(18):5321-33.
1998: La Starza R; Wlodarska I; Matteucci C; Falzetti D; Baens M; Martelli M F; Van den Berghe H; Marynen P; Mecucci C
Rearrangement between the MYH11 gene at 16p13 and D12S158 at 12p13 in a case of acute myeloid leukemia M1 (AML-M1).
Genes, chromosomes & cancer 1998;23(1):10-5.
1998: Hoornaert I; Marynen P; Baens M
CREBL2, a novel transcript from the chromosome 12 region flanked by ETV6 and CDKN1B.
Genomics 1998;51(1):154-7.
1998: Wlodarska I; La Starza R; Baens M; Dierlamm J; Uyttebroeck A; Selleslag D; Francine A; Mecucci C; Hagemeijer A; Van den Berghe H; Marynen P
Fluorescence in situ hybridization characterization of new translocations involving TEL (ETV6) in a wide spectrum of hematologic malignancies.
Blood 1998;91(4):1399-406.
1998: Dal Cin P; Dei Tos A P; Qi H; Giannini C; Furlanetto A; Longatti P L; Marynen P; Van den Berghe H
Immature teratoma of the pineal gland with isochromosome 12p.
Acta neuropathologica 1998;95(1):107-10.
1998: Vermeesch J R; Falzetti D; Van Buggenhout G; Fryns J P; Marynen P
Chromosome healing of constitutional chromosome deletions studied by microdissection.
Cytogenetics and cell genetics 1998;81(1):68-72.
1997: Baens M; Marynen P
A human homologue (BICD1) of the Drosophila bicaudal-D gene.
Genomics 1997;45(3):601-6.
1997: Peeters P; Raynaud S D; Cools J; Wlodarska I; Grosgeorge J; Philip P; Monpoux F; Van Rompaey L; Baens M; Van den Berghe H; Marynen P
Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia.
Blood 1997;90(7):2535-40.
1997: Van Rompaey L; Ayoubi T; Van De Ven W; Marynen P
Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered alpha 2-macroglobulin containing a furin recognition sequence in the bait region.
The Biochemical journal 1997;326 ( Pt 2)():507-14.
1997: Vanhooren J C; Marynen P; Mannaerts G P; Van Veldhoven P P
Evidence for the existence of a pristanoyl-CoA oxidase gene in man.
The Biochemical journal 1997;325 ( Pt 3)():593-9.
1997: Vermeesch J R; Petit P; Speleman F; Devriendt K; Fryns J P; Marynen P
Interstitial telomeric sequences at the junction site of a jumping translocation.
Human genetics 1997;99(6):735-7.
1997: Devriendt K; Petit P; Matthijs G; Vermeesch J R; Holvoet M; De Muelenaere A; Marynen P; Cassiman J J; Fryns J P
Trisomy 15 rescue with jumping translocation of distal 15q in Prader-Willi syndrome.
Journal of medical genetics 1997;34(5):395-9.
1997: Wlodarska I; Aventín A; Inglés-Esteve J; Falzetti D; Criel A; Cassiman J J; Mecucci C; Van den Berghe H; Marynen P
A new subtype of pre-B acute lymphoblastic leukemia with t(5;12)(q31q33;p12), molecularly and cytogenetically distinct from t(5;12) in chronic myelomonocytic leukemia.
Blood 1997;89(5):1716-22.
1997: Veugelers M; Vermeesch J; Reekmans G; Steinfeld R; Marynen P; David G
Characterization of glypican-5 and chromosomal localization of human GPC5, a new member of the glypican gene family.
Genomics 1997;40(1):24-30.
1997: Peeters P; Wlodarska I; Baens M; Criel A; Selleslag D; Hagemeijer A; Van den Berghe H; Marynen P
Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in myeloproliferative disorders.
Cancer research 1997;57(4):564-9.
1997: Vermeesch J R; Petit P; Kermouni A; Renauld J C; Van Den Berghe H; Marynen P
The IL-9 receptor gene, located in the Xq/Yq pseudoautosomal region, has an autosomal origin, escapes X inactivation and is expressed from the Y.
Human molecular genetics 1997;6(1):1-8.
1996: Fransen M; Marynen P; Baumgart E; Vanhooren J C; Mannaerts G P; Van Veldhoven P P
Further characterization of the human peroxisomal C-terminal targeting signal protein import receptor.
Annals of the New York Academy of Sciences 1996;804():672-3.
1996: Baumgart E; Vanhooren J C; Fransen M; Marynen P; Puype M; Vandekerckhove J; Leunissen J A; Fahimi H D; Mannaerts G P; van Veldhoven P P
Molecular characterization of the human peroxisomal branched-chain acyl-CoA oxidase: cDNA cloning, chromosomal assignment, tissue distribution, and evidence for the absence of the protein in Zellweger syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(24):13748-53.
1996: Wlodarska I; Mecucci C; Baens M; Marynen P; van den Berghe H
ETV6 gene rearrangements in hematopoietic malignant disorders.
Leukemia & lymphoma 1996;23(3-4):287-95.
1996: Dal Cin P; Marynen P; Moerman P; Vergot I; Van den Berghe H
Ovarian germ cell tumor with chromosome 12 anomaly but without i(12p).
Cancer genetics and cytogenetics 1996;91(1):61-4.
1996: Claes S; Gu X X; Legius E; Lorenzetti E; Marynen P; Fryns J P; Cassiman J J; Raeymaekers P
Linkage analysis in three families with nonspecific X-linked mental retardation.
American journal of medical genetics 1996;64(1):137-46.
1996: Raynaud S D; Baens M; Grosgeorge J; Rodgers K; Reid C D; Dainton M; Dyer M; Fuzibet J G; Gratecos N; Taillan B; Ayraud N; Marynen P
Fluorescence in situ hybridization analysis of t(3; 12)(q26; p13): a recurring chromosomal abnormality involving the TEL gene (ETV6) in myelodysplastic syndromes.
Blood 1996;88(2):682-9.
1996: Ding H; Descheemaeker K; Marynen P; Nelles L; Carvalho T; Carmo-Fonseca M; Collen D; Belayew A
Characterization of a helicase-like transcription factor involved in the expression of the human plasminogen activator inhibitor-1 gene.
DNA and cell biology 1996;15(6):429-42.
1996: Wlodarska I; Baens M; Peeters P; Aerssens J; Mecucci C; Brock P; Marynen P; Van den Berghe H
Biallelic alterations of both ETV6 and CDKN1B genes in a t(12;21) childhood acute lymphoblastic leukemia case.
Cancer research 1996;56(11):2655-61.
1996: Baens M; Peeters P; Guo C; Aerssens J; Marynen P
Genomic organization of TEL: the human ETS-variant gene 6.
Genome research 1996;6(5):404-13.
1996: Raynaud S; Cave H; Baens M; Bastard C; Cacheux V; Grosgeorge J; Guidal-Giroux C; Guo C; Vilmer E; Marynen P; Grandchamp B
The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia.
Blood 1996;87(7):2891-9.
1996: Gu X X; Decorte R; Marynen P; Fryns J P; Cassiman J J; Raeymaekers P
Localisation of a new gene for non-specific mental retardation to Xq22-q26 (MRX35).
Journal of medical genetics 1996;33(1):52-5.
1996: Wlodarska I; Marynen P; La Starza R; Mecucci C; Van den Berghe H
The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignancies.
Cytogenetics and cell genetics 1996;72(2-3):229-35.
1996: Vermeesch J R; De Meurichy W; Van Den Berghe H; Marynen P; Petit P
Differences in the distribution and nature of the interstitial telomeric (TTAGGG)n sequences in the chromosomes of the Giraffidae, okapai (Okapia johnstoni), and giraffe (Giraffa camelopardalis): evidence for ancestral telomeres at the okapi polymorphic rob(5;26) fusion site.
Cytogenetics and cell genetics 1996;72(4):310-5.
1995: Marynen P; Fransen M; Raeymaekers P; Mannaerts G P; Van Veldhoven P P
The gene for the peroxisomal targeting signal import receptor (PXR1) is located on human chromosome 12p13, flanked by TPI1 and D12S1089.
Genomics 1995;30(2):366-8.
1995: Van Rompaey L; Proost P; Van den Berghe H; Marynen P
Design of a new protease inhibitor by the manipulation of the bait region of alpha 2-macroglobulin: inhibition of the tobacco etch virus protease by mutant alpha 2-macroglobulin.
The Biochemical journal 1995;312 ( Pt 1)():191-5.
1995: Van Rompaey L; Van den Berghe H; Marynen P
Synthesis of a Cys949Tyr alpha 2-macroglobulin thiol ester mutant: co-transfection with wild-type alpha 2-macroglobulin in an episomal expression system.
The Biochemical journal 1995;312 ( Pt 1)():183-90.
1995: Baens M; Aerssens J; van Zand K; Van den Berghe H; Marynen P
Isolation and regional assignment of human chromosome 12p cDNAs.
Genomics 1995;29(1):44-52.
1995: Raeymaekers P; Van Zand K; Jun L; Höglund M; Cassiman J J; Van den Berghe H; Marynen P
A radiation hybrid map with 60 loci covering the entire short arm of chromosome 12.
Genomics 1995;29(1):170-8.
1995: Ruiz J C; Cuppens H; Legius E; Fryns J P; Glover T; Marynen P; Cassiman J J
Mutations in L1-CAM in two families with X linked complicated spastic paraplegia, MASA syndrome, and HSAS.
Journal of medical genetics 1995;32(7):549-52.
1995: Ghabanbasani M Z; Gu X X; Spaepen M; Vandevyver C; Raus J; Marynen P; Carton H; Cassiman J J
Importance of HLA-DRB1 and DQA1 genes and of the amino acid polymorphisms in the functional domain of DR beta 1 chain in multiple sclerosis.
Journal of neuroimmunology 1995;59(1-2):77-82.
1995: Wlodarska I; Mecucci C; Marynen P; Guo C; Franckx D; La Starza R; Aventin A; Bosly A; Martelli M F; Cassiman J J
TEL gene is involved in myelodysplastic syndromes with either the typical t(5;12)(q33;p13) translocation or its variant t(10;12)(q24;p13).
Blood 1995;85(10):2848-52.
1995: Ghabanbasani M Z; Spaepen M; Buyse I; Legius E; Decorte R; Bex M; Marynen P; Bouillon R; Cassiman J J
Increased and decreased relative risk for non-insulin-dependent diabetes mellitus conferred by HLA class II and by CD4 alleles.
Clinical genetics 1995;47(5):225-30.
1995: Guo C; Van Damme B; Vanrenterghem Y; Devriendt K; Cassiman J J; Marynen P
Severe alport phenotype in a woman with two missense mutations in the same COL4A5 gene and preponderant inactivation of the X chromosome carrying the normal allele.
The Journal of clinical investigation 1995;95(4):1832-7.
1995: Legius E; Wu R; Eyssen M; Marynen P; Fryns J P; Cassiman J J
Encephalocraniocutaneous lipomatosis with a mutation in the NF1 gene.
Journal of medical genetics 1995;32(4):316-9.
1995: Vermeesch J R; Mertens G; David G; Marynen P
Assignment of the human glypican gene (GPC1) to 2q35-q37 by fluorescence in situ hybridization.
Genomics 1995;25(1):327-9.
1995: Chaffanet M; Baens M; Aerssens J; Schoenmakers E; Cassiman J J; Marynen P
Mapping of an ordered set of 14 cosmids to human chromosome 12p by two-color in situ hybridization.
Cytogenetics and cell genetics 1995;69(1-2):27-32.
1995: Aerssens J; Guo C; Vermeesch J; Baens M; Browne D; Litt M; Van Den Berghe H; Marynen P
A physical map of the region spanning the chromosome 12 translocation breakpoint in a mesothelioma with a t(X;12)(q22;p13).
Cytogenetics and cell genetics 1995;71(3):268-75.
1994: Zamani M G; De Hert M; Spaepen M; Hermans M; Marynen P; Cassiman J J; Peuskens J
Study of the possible association of HLA class II, CD4, and CD3 polymorphisms with schizophrenia.
American journal of medical genetics 1994;54(4):372-7.
1994: Ghabanbasani M Z; Buyse I; Legius E; Decorte R; Marynen P; Bouillon R; Cassiman J J
Possible association of CD3 and CD4 polymorphisms with insulin-dependent diabetes mellitus (IDDM).
Clinical and experimental immunology 1994;97(3):517-21.
1994: Ruiz J C; Legius E; Cuppens H; Moens P; Marynen P; Cassiman J J
Exclusion of linkage to 14q23-24 in a family with Holt-Oram syndrome.
Clinical genetics 1994;46(3):257-9.
1994: Van Rompaey L; Marynen P
Temperature-dependent biosynthesis of thiol esters in baculovirus recombinant alpha 2M and PZP.
Annals of the New York Academy of Sciences 1994;737():506-9.
1994: Matthijs G; Marynen P
The promoter of the human alpha 2-macroglobulin gene binds HNF-4 or a related nuclear factor for its expression in hepatocytes and lung fibroblasts.
Annals of the New York Academy of Sciences 1994;737():472-5.
1994: Buyse I; Sandkuyl L A; Zamani Ghabanbasani M; Gu X X; Bouillon R; Bex M; Dooms L; Emonds M P; Duhamel M; Marynen P
Association of particular HLA class II alleles, haplotypes and genotypes with susceptibility to IDDM in the Belgian population.
Diabetologia 1994;37(8):808-17.
1994: Legius E; Dierick H; Wu R; Hall B K; Marynen P; Cassiman J J; Glover T W
TP53 mutations are frequent in malignant NF1 tumors.
Genes, chromosomes & cancer 1994;10(4):250-5.
1994: De Meirsman C; Schollen E; Jaspers M; Ongena K; Matthijs G; Marynen P; Cassiman J J
Cloning and characterization of the promoter region of the murine alpha-4 integrin subunit.
DNA and cell biology 1994;13(7):743-54.
1994: Matthijs G; Cassiman J J; Van den Berghe H; Marynen P
Characterization of the human alpha 2-macroglobulin gene promoter: identification of a novel, triple TRE/RARE/ERE response element.
Biochemical and biophysical research communications 1994;202(1):65-72.
1994: Baens M; Chaffanet M; Aerssens J; Cassiman J J; Marynen P
Assignment of the gene for the human proliferating cell nucleolar protein P120 (NOL1) to chromosome 12p13 by fluorescence in situ hybridization and polymerase chain reaction with somatic cell hybrids.
Genomics 1994;21(1):296-7.
1994: Legius E; de Die-Smulders C E; Verbraak F; Habex H; Decorte R; Marynen P; Fryns J P; Cassiman J J
Genetic heterogeneity in Rieger eye malformation.
Journal of medical genetics 1994;31(4):340-1.
1994: Aly M S; Dal Cin P; Jiskoot P; Deneffe G; Marynen P; Van den Berghe H
Competitive in situ hybridization in a mediastinal germ cell tumor.
Cancer genetics and cytogenetics 1994;73(1):53-6.
1994: Decorte R; Wu R; Marynen P; Cassiman J J
Identification of internal variation in the pseudoautosomal VNTR DXYS17, with nonrandom distribution of the alleles on the X and the Y chromosomes.
American journal of human genetics 1994;54(3):506-15.
1994: Aerssens J; Chaffanet M; Baens M; Matthijs G; Van den Berghe H; Cassiman J J; Marynen P
Regional assignment of seven loci to 12p13.2-pter by PCR analysis of somatic cell hybrids containing the der(12) or the der(X) chromosome from a mesothelioma showing t(X;12)(q22;p13).
Genomics 1994;20(1):119-21.
1994: Kools P F; Roebroek A J; Van de Velde H J; Marynen P; Bullerdiek J; Van de Ven W J
Regional mapping of the human NSP gene to chromosome region 14q21-->q22 by fluorescence in situ hybridization analysis.
Cytogenetics and cell genetics 1994;66(1):48-50.
1994: Legius E; Cuppens H; Dierick H; Van Zandt K; Dom R; Fryns J P; Evers-Kiebooms G; Decruyenaere M; Demyttenaere K; Marynen P
Limited expansion of the (CAG)n repeat of the Huntington gene: a premutation (?).
European journal of human genetics : EJHG 1994;2(1):44-50.
1994: Zamani Ghabanbasani M; Spaepen M; Buyse I; Marynen P; Bex M; Bouillon R; Cassiman J J
Improved risk assessment for insulin-dependent diabetes mellitus by analysis of amino acids in HLA-DQ and DRB1 loci.
European journal of human genetics : EJHG 1994;2(3):177-84.
1993: Guo C; Van Damme B; Van Damme-Lombaerts R; Van den Berghe H; Cassiman J J; Marynen P
Differential splicing of COL4A5 mRNA in kidney and white blood cells: a complex mutation in the COL4A5 gene of an Alport patient deletes the NC1 domain.
Kidney international 1993;44(6):1316-21.
1993: Wu R; Cuppens H; Buyse I; Decorte R; Marynen P; Gordts S; Cassiman J J
Co-amplification of the cystic fibrosis delta F508 mutation with the HLA DQA1 sequence in single cell PCR: implications for improved assessment of polar bodies and blastomeres in preimplantation diagnosis.
Prenatal diagnosis 1993;13(12):1111-22.
1993: Cuppens H; Marynen P; De Boeck C; Cassiman J J
Detection of 98.5% of the mutations in 200 Belgian cystic fibrosis alleles by reverse dot-blot and sequencing of the complete coding region and exon/intron junctions of the CFTR gene.
Genomics 1993;18(3):693-7.
1993: David G; Bai X M; Van der Schueren B; Marynen P; Cassiman J J; Van den Berghe H
Spatial and temporal changes in the expression of fibroglycan (syndecan-2) during mouse embryonic development.
Development (Cambridge, England) 1993;119(3):841-54.
1993: Dierick H; Stul M; De Kelver W; Marynen P; Cassiman J J
Incorporation of dITP or 7-deaza dGTP during PCR improves sequencing of the product.
Nucleic acids research 1993;21(18):4427-8.
1993: Guo C; Marynen P; Cassiman J J
A rapid, semiautomated method for apolipoprotein E genotyping.
PCR methods and applications 1993;2(4):348-50.
1993: Devriendt K; Massa G; de Zegher F; Vanderschueren-Lodeweyckx M; Cassiman J J; Van den Berghe H; Marynen P
Opposite effects of growth hormone and estrogens on the pregnancy zone protein serum levels in children and adolescents.
Acta endocrinologica 1993;128(4):334-8.
1993: Baens M; Chaffanet M; Cassiman J J; van den Berghe H; Marynen P
Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid.
Genomics 1993;16(1):214-8.
1993: Buyse I; Decorte R; Baens M; Cuppens H; Semana G; Emonds M P; Marynen P; Cassiman J J
Rapid DNA typing of class II HLA antigens using the polymerase chain reaction and reverse dot blot hybridization.
Tissue antigens 1993;41(1):1-14.
1993: Buyse I; Emonds M P; Bouillon R; Marynen P; Cassiman J J
Novel class II HLA-DRB4 and DPB1 alleles found in the Belgian population.
Immunogenetics 1993;38(5):380.
1992: Spaepen M; Angulo A F; Marynen P; Cassiman J J
Detection of bacterial and mycoplasma contamination in cell cultures by polymerase chain reaction.
FEMS microbiology letters 1992;78(1):89-94.
1992: David G; van der Schueren B; Marynen P; Cassiman J J; van den Berghe H
Molecular cloning of amphiglycan, a novel integral membrane heparan sulfate proteoglycan expressed by epithelial and fibroblastic cells.
The Journal of cell biology 1992;118(4):961-9.
1992: Cuppens H; Loumi O; Marynen P; Cassiman J J
Identification of a new frameshift mutation and a duplication polymorphism in the CFTR gene in the Algerian population.
Human molecular genetics 1992;1(4):283-4.
1992: Wlodarska I; Mecucci C; Vandenberghe E; De Wolf-Peeters C; Thomas J; Hilliker C; Schoenmakers E; Stul M; Marynen P; Cassiman J J
dup(12)(q13----qter) in two t(14;18)-negative follicular B-non-Hodgkin's lymphomas.
Genes, chromosomes & cancer 1992;4(4):302-8.
1992: Matthijs G; Devriendt K; Cassiman J J; Van den Berghe H; Marynen P
Structure of the human alpha-2 macroglobulin gene and its promotor.
Biochemical and biophysical research communications 1992;184(2):596-603.
1992: Cuppens H; Buyse I; Baens M; Marynen P; Cassiman J J
Simultaneous screening for 11 mutations in the cystic fibrosis transmembrane conductance regulator gene by multiplex amplification and reverse dot-blot.
Molecular and cellular probes 1992;6(1):33-9.
1992: Loumi O; Cuppens H; Bakour R; Benabadji M; Baghriche M; Marynen P; Cassiman J J
An Algerian child homozygous for the M470V polymorphism and for a deletion of two nucleotides in exon 10 of the CFTR gene, shows severe cystic fibrosis symptoms.
Genetic counseling (Geneva, Switzerland) 1992;3(4):205-7.
1991: Zhang Z H; Vekemans S; Aly M S; Jaspers M; Marynen P; Cassiman J J
The gene for the alpha 4 subunit of the VLA-4 integrin maps to chromosome 2Q31-32.
Blood 1991;78(9):2396-9.
1991: Jaspers M; Marynen P; Aly M S; Cuppens H; Hilliker C; Cassiman J J
Localization of the gene encoding the alpha 2 subunit of the human VLA-2 receptor to chromosome 5q23-31.
Somatic cell and molecular genetics 1991;17(5):505-11.
1991: Matthijs G; Marynen P
A deletion polymorphism in the human alpha-2-macroglobulin (A2M) gene.
Nucleic acids research 1991;19(18):5102.
1991: Hilliker C E; Darville M I; Aly M S; Chikri M; Szpirer C; Marynen P; Rousseau G G; Cassiman J J
Human and rat chromosomal localization of two genes for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by analysis of somatic cell hybrids and in situ hybridization.
Genomics 1991;10(4):867-73.
1991: Devriendt K; Van den Berghe H; Cassiman J J; Marynen P
Primary structure of pregnancy zone protein. Molecular cloning of a full-length PZP cDNA clone by the polymerase chain reaction.
Biochimica et biophysica acta 1991;1088(1):95-103.
1990: David G; Lories V; Decock B; Marynen P; Cassiman J J; Van den Berghe H
Molecular cloning of a phosphatidylinositol-anchored membrane heparan sulfate proteoglycan from human lung fibroblasts.
The Journal of cell biology 1990;111(6 Pt 2):3165-76.
1990: Cuppens H; Marynen P; De Boeck C; De Baets F; Eggermont E; Van den Berghe H; Cassiman J J
A child, homozygous for a stop codon in exon 11, shows milder cystic fibrosis symptoms than her heterozygous nephew.
Journal of medical genetics 1990;27(11):717-9.
1990: Cuppens H; Legius E; Cabello P; Marynen P; De Boeck C; Decorte R; Fryns J P; Eggermont E; Van den Berghe H; Cassiman J J
Association between XV2c/CS7/KM19/D9 haplotypes and the delta F508 mutation. A study of 57 Belgian families.
Human genetics 1990;85(4):402-3.
1990: Legius E; Baten E; Stul M; Marynen P; Cassiman J J
Sporadic late onset ornithine transcarbamylase deficiency in a boy with somatic mosaicism for an intragenic deletion.
Clinical genetics 1990;38(2):155-9.
1990: Decorte R; Cuppens H; Marynen P; Cassiman J J
Rapid detection of hypervariable regions by the polymerase chain reaction technique.
DNA and cell biology 1990;9(6):461-9.
1990: Decorte R; Hilliker C; Marynen P; Cassiman J J
Rapid and simple detection of minisatellite regions in forensic DNA samples by the polymerase chain reaction combined with a chemiluminescence method.
Trends in genetics : TIG 1990;6(6):172-3.
1990: Zhang J; Devriendt K; Marynen P; Van den Berghe H; Cassiman J J
Chromosome mapping using polymerase chain reaction on somatic cell hybrids.
Cancer genetics and cytogenetics 1990;45(2):217-21.
1990: Marynen P; Devriendt K; Van den Berghe H; Cassiman J J
A genetic polymorphism in a functional domain of human pregnancy zone protein: the bait region. Genomic structure of the bait domains of human pregnancy zone protein and alpha 2 macroglobulin.
FEBS letters 1990;262(2):349-52.
1989: Zhang J; Marynen P; Devriendt K; Fryns J P; Van den Berghe H; Cassiman J J
Molecular analysis of the isochromosome 12P in the Pallister-Killian syndrome. Construction of a mouse-human hybrid cell line containing an i(12p) as the sole human chromosome.
Human genetics 1989;83(4):359-63.
1989: Devriendt K; Zhang J; van Leuven F; van den Berghe H; Cassiman J J; Marynen P
A cluster of alpha 2-macroglobulin-related genes (alpha 2 M) on human chromosome 12p: cloning of the pregnancy-zone protein gene and an alpha 2M pseudogene.
Gene 1989;81(2):325-34.
1989: Marynen P; Zhang J; Cassiman J J; Van den Berghe H; David G
Partial primary structure of the 48- and 90-kilodalton core proteins of cell surface-associated heparan sulfate proteoglycans of lung fibroblasts. Prediction of an integral membrane domain and evidence for multiple distinct core proteins at the cell surface of human lung fibroblasts.
The Journal of biological chemistry 1989;264(12):7017-24.
1988: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Mapping of structure-function relationships in proteins with a panel of monoclonal antibodies. A study on human alpha 2 macroglobulin.
Journal of immunological methods 1988;111(1):39-49.
1988: Deichmann K; Marynen P; Van den Berghe H; Cassiman J J
Rat hemoglobin interferes with DNA migration in agarose gels.
Nucleic acids research 1988;16(7):3110.
1988: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Proteolysis of human alpha 2-macroglobulin without hydrolysis of the internal thiolesters or expression of the receptor recognition site.
The Journal of biological chemistry 1988;263(1):468-71.
1988: Zhang J; Dirckx L; Marynen P; Rombauts W; Delaey B; Van den Berghe H; Cassiman J J
Mapping of rat prostatic binding protein genes C1, C2, and C3 to rat chromosome 5 by in situ hybridization.
Cytogenetics and cell genetics 1988;48(2):121-3.
1987: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
A mouse monoclonal antibody to human alpha 2-macroglobulin (alpha 2M) crossreacts with alpha 2M from mouse: epitope mapping and characterization of subunit structure of murine alpha 2M.
Journal of biochemistry 1987;101(5):1181-9.
1981: Van Leuven F; Marynen P; Cassiman J J; Van den Berghe H
Receptor-mediated endocytosis of alpha 2macroglobulin-protease complexes by fibroblasts in culture. Competitive inhibition by bacitracin.
FEBS letters 1981;134(1):83-7.

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