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Edmund Maser

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Tereza Hartmanová; Juraj Lenčo; Edmund Maser; Claudia A Staab-Weijnitz; Vojtěch Tambor; Vladimír Wsól
S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.
Mingtang Li; Guangming Xiong; Edmund Maser
A novel transcriptional repressor PhaR for the steroid-inducible expression of the 3,17β-hydroxysteroid dehydrogenase gene in Comamonas testosteroni ATCC11996.
Tingdi Zhang; Guangming Xiong; Edmund Maser
Analysis and characterization of eight estradiol inducible genes and a strong promoter from the steroid degrading marine bacterial strain S19-1.

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2013: Tereza Hartmanová; Juraj Lenčo; Edmund Maser; Claudia A Staab-Weijnitz; Vojtěch Tambor; Vladimír Wsól
S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.
Chemico-biological interactions 2013;202(1-3):136-45.
2013: Mingtang Li; Guangming Xiong; Edmund Maser
A novel transcriptional repressor PhaR for the steroid-inducible expression of the 3,17β-hydroxysteroid dehydrogenase gene in Comamonas testosteroni ATCC11996.
Chemico-biological interactions 2013;202(1-3):116-25.
2013: Tingdi Zhang; Guangming Xiong; Edmund Maser
Analysis and characterization of eight estradiol inducible genes and a strong promoter from the steroid degrading marine bacterial strain S19-1.
Chemico-biological interactions 2013;202(1-3):159-67.
2013: Yanyan Han; Claudia A Staab-Weijnitz; Guangming Xiong; Edmund Maser
Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression.
The Journal of steroid biochemistry and molecular biology 2013;133():129-39.
2012: Wenjie Gong; Guangming Xiong; Edmund Maser
Oligomerization and negative autoregulation of the LysR-type transcriptional regulator HsdR from Comamonas testosteroni.
The Journal of steroid biochemistry and molecular biology 2012;132(3-5):203-11.
2012: Di-Xian Luo; Deliang Cao; Duan-Fang Liao; Sandeep Rajput; Di-Jun Tong; Chun Wang; Edmund Maser
Targeting acetyl-CoA carboxylases: small molecular inhibitors and their therapeutic potential.
Recent patents on anti-cancer drug discovery 2012;7(2):168-84.
2012: Petra Malátková; Bettina Ebert; Vladimír Wsól; Edmund Maser
Expression of human carbonyl reductase 3 (CBR3; SDR21C2) is inducible by pro-inflammatory stimuli.
Biochemical and biophysical research communications 2012;420(2):368-73.
2012: Edmund Maser; Tea Lanišnik Rižner
Steroids and microorganisms.
The Journal of steroid biochemistry and molecular biology 2012;129(1-2):1-3.
2012: Michael Kisiela; Bettina Ebert; Adam Skarka; Edmund Maser
Hydroxysteroid dehydrogenases (HSDs) in bacteria: a bioinformatic perspective.
The Journal of steroid biochemistry and molecular biology 2012;129(1-2):31-46.
2012: Yingying Sang; Guangming Xiong; Edmund Maser
Identification of a new steroid degrading bacterial strain H5 from the Baltic Sea and isolation of two estradiol inducible genes.
The Journal of steroid biochemistry and molecular biology 2012;129(1-2):22-30.
2012: Wenjie Gong; Guangming Xiong; Edmund Maser
Cloning, expression and characterization of a novel short-chain dehydrogenase/reductase (SDRx) in Comamonas testosteroni.
The Journal of steroid biochemistry and molecular biology 2012;129(1-2):15-21.
2012: Lars Radünz; Edmund Maser; Folker Westphal; Gertrud Rochholz
THCVA-A - a new additional marker for illegal cannabis consumption.
Forensic science international 2012;215(1-3):171-4.
2012: Edmund Maser
16th Carbonyl Metabolism Meeting: from enzymology to genomics.
Human genomics 2012;6():25.
2012: Andreas Blum; Christine Loerz; Hans-Joerg Martin; Claudia A Staab-Weijnitz; Edmund Maser
Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor.
The Journal of steroid biochemistry and molecular biology 2012;128(1-2):51-5.
2011: Michael Kisiela; Yasser El-Hawari; Hans-Jörg Martin; Edmund Maser
Bioinformatic and biochemical characterization of DCXR and DHRS2/4 from Caenorhabditis elegans.
Chemico-biological interactions 2011;191(1-3):75-82.
2011: Yingying Sang; Guangming Xiong; Edmund Maser
Steroid degradation and two steroid-inducible enzymes in the marine bacterium H5.
Chemico-biological interactions 2011;191(1-3):89-94.
2011: Claudia A Staab; Tereza Hartmanová; Yasser El-Hawari; Bettina Ebert; Michael Kisiela; Vladimir Wsol; Hans-Jörg Martin; Edmund Maser
Studies on reduction of S-nitrosoglutathione by human carbonyl reductases 1 and 3.
Chemico-biological interactions 2011;191(1-3):95-103.
2011: Claudia A Staab; Jochen P Stegk; Elisabeth Neiss; Ingolf Cascorbi; Bettina Ebert; Sierk Haenisch; Katrin Köbsch; Edmund Maser
Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method.
Chemico-biological interactions 2011;191(1-3):104-12.
2011: Bettina Ebert; Michael Kisiela; Vladimir Wsól; Edmund Maser
Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29.
Chemico-biological interactions 2011;191(1-3):239-49.
2011: Tingdi Zhang; Guangming Xiong; Edmund Maser
Characterization of the steroid degrading bacterium S19-1 from the Baltic Sea at Kiel, Germany.
Chemico-biological interactions 2011;191(1-3):83-8.
2011: Hans-Jörg Martin; Marta Ziemba; Michael Kisiela; José A Botella; Stephan Schneuwly; Edmund Maser
The Drosophila carbonyl reductase sniffer is an efficient 4-oxonon-2-enal (4ONE) reductase.
Chemico-biological interactions 2011;191(1-3):48-54.
2010: Sibylle Brenner; Michael Gülden; Edmund Maser; Hasso Seibert
Lasting effect of preceding culture conditions on the susceptibility of C6 cells to peroxide-induced oxidative stress.
Toxicology in vitro : an international journal published in association with BIBRA 2010;24(8):2090-6.
2010: Michael Gülden; Anne Jess; Julia Kammann; Edmund Maser; Hasso Seibert
Cytotoxic potency of H2O2 in cell cultures: impact of cell concentration and exposure time.
Free radical biology & medicine 2010;49(8):1298-305.
2010: Bettina Ebert; Michael Kisiela; Petra Malátková; Yasser El-Hawari; Edmund Maser
Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.
Biochemistry 2010;49(39):8499-511.
2010: Petra Malátková; Edmund Maser; Vladimír Wsól
Human carbonyl reductases.
Current drug metabolism 2010;11(8):639-58.
2010: Edmund Maser; Guangming Xiong
The Comamonas testosteroni steroid biosensor system (COSS)--reflection on other methods.
The Journal of steroid biochemistry and molecular biology 2010;121(3-5):633-40.
2010: Claudia Röhl; Elisabeth Armbrust; Eva Herbst; Anne Jess; Michael Gülden; Edmund Maser; Gerald Rimbach; Christine Bösch-Saadatmandi
Mechanisms involved in the modulation of astroglial resistance to oxidative stress induced by activated microglia: antioxidative systems, peroxide elimination, radical generation, lipid peroxidation.
Neurotoxicity research 2010;17(4):317-31.
2010: Claudia A Staab; Edmund Maser
11beta-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation.
The Journal of steroid biochemistry and molecular biology 2010;119(1-2):56-72.
2009: Milena Rüweler; Michael Gülden; Edmund Maser; Marek Murias; Hasso Seibert
Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro.
Chemico-biological interactions 2009;182(2-3):128-35.
2009: Claudia Röhl; M Grell; Edmund Maser
The organotin compounds trimethyltin (TMT) and triethyltin (TET) but not tributyltin (TBT) induce activation of microglia co-cultivated with astrocytes.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(8):1541-7.
2009: Lucie Skarydová; Adam Skarka; Romana Novotná; Lucie Zivná; Hans-Jörg Martin; Vladimír Wsól; Edmund Maser
Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin.
Toxicology 2009;264(1-2):52-60.
2009: J P Stegk; B Ebert; Hans-Jörg Martin; Edmund Maser
Expression profiles of human 11beta-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases.
Molecular and cellular endocrinology 2009;301(1-2):104-8.
2009: Andreas Blum; Angelo D Favia; Edmund Maser
11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds.
Molecular and cellular endocrinology 2009;301(1-2):132-6.
2009: Yasser El-Hawari; Angelo D Favia; Ewa S Pilka; Michael Kisiela; Udo Oppermann; Hans-Jörg Martin; Edmund Maser
Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.
Chemico-biological interactions 2009;178(1-3):234-41.
2009: Ganesaratnam K Balendiran; Hans-Jörg Martin; Yasser El-Hawari; Edmund Maser
Cancer biomarker AKR1B10 and carbonyl metabolism.
Chemico-biological interactions 2009;178(1-3):134-7.
2009: Guangming Xiong; Evelyn Draus; Yijing Luo; Edmund Maser
3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase as a tool for isolation and characterization of a new marine steroid degrading bacterial strain.
Chemico-biological interactions 2009;178(1-3):206-10.
2009: Hans-Jörg Martin; Edmund Maser
Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes.
Chemico-biological interactions 2009;178(1-3):145-50.
2009: Lucie Skarydová; Lucie Zivná; Guangming Xiong; Edmund Maser; Vladimír Wsól
AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids.
Chemico-biological interactions 2009;178(1-3):138-44.
2009: Guangming Xiong; Yijing Luo; Saihong Jin; Edmund Maser
Cis- and trans-regulatory elements of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase as biosensor system for steroid determination in the environment.
Chemico-biological interactions 2009;178(1-3):215-20.
2009: Ewa S Pilka; Frank H Niesen; Wen-Hwa Lee; Yasser El-Hawari; James E Dunford; Grazyna Kochan; Vladimir Wsol; Hans-Joerg Martin; Edmund Maser; Udo Oppermann
Structural basis for substrate specificity in human monomeric carbonyl reductases.
PloS one 2009;4(10):e7113.
2008: Romana Novotna; Vladimir Wsol; Guangming Xiong; Edmund Maser
Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3.
Toxicology letters 2008;181(1):1-6.
2008: Claudia Röhl; Elisabeth Armbrust; Karola Kolbe; Ralph Lucius; Edmund Maser; Simone Venz; Michael Gülden
Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in vitro.
Glia 2008;56(10):1114-26.
2008: Milena Rüweler; Anika Anker; Michael Gülden; Edmund Maser; Hasso Seibert
Inhibition of peroxide-induced radical generation by plant polyphenols in C6 astroglioma cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(5):1377-81.
2008: Arne Linden; Michael Gülden; Hans-Jörg Martin; Edmund Maser; Hasso Seibert
Peroxide-induced cell death and lipid peroxidation in C6 glioma cells.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(5):1371-6.
2008: André Göhler; Guangming Xiong; Simone Paulsen; Gabriele Trentmann; Edmund Maser
Testosterone-inducible regulator is a kinase that drives steroid sensing and metabolism in Comamonas testosteroni.
The Journal of biological chemistry 2008;283(25):17380-90.
2007: Mariann Plebuch; Michael Soldan; Christoph Hungerer; Lutz Koch; Edmund Maser
Increased resistance of tumor cells to daunorubicin after transfection of cDNAs coding for anthracycline inactivating enzymes.
Cancer letters 2007;255(1):49-56.
2007: Vladimir Wsol; Barbora Szotakova; Hans-Jörg Martin; Edmund Maser
Aldo-keto reductases (AKR) from the AKR1C subfamily catalyze the carbonyl reduction of the novel anticancer drug oracin in man.
Toxicology 2007;238(2-3):111-8.
2007: Frank Hoffmann; Christoph A Sotriffer; Andreas Evers; Guangming Xiong; Edmund Maser
Understanding oligomerization in 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: an in silico approach and evidence for an active protein.
Journal of biotechnology 2007;129(1):131-9.
2007: Frank Hoffmann; Edmund Maser
Carbonyl reductases and pluripotent hydroxysteroid dehydrogenases of the short-chain dehydrogenase/reductase superfamily.
Drug metabolism reviews 2007;39(1):87-144.
2006: Edmund Maser; Vladimir Wsol; Hans-Jörg Martin
11Beta-hydroxysteroid dehydrogenase type 1: purification from human liver and characterization as carbonyl reductase of xenobiotics.
Molecular and cellular endocrinology 2006;248(1-2):34-7.
2006: Hans-Jörg Martin; Ursula Breyer-Pfaff; Vladimir Wsol; Simone Venz; Simone Block; Edmund Maser
Purification and characterization of akr1b10 from human liver: role in carbonyl reduction of xenobiotics.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(3):464-70.
2006: Edmund Maser
Neuroprotective role for carbonyl reductase?
Biochemical and biophysical research communications 2006;340(4):1019-22.
2004: Ursula Breyer-Pfaff; Hans-Jörg Martin; Michael Ernst; Edmund Maser
Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(9):915-22.
2003: Guangming Xiong; Hans-Jörg Martin; Edmund Maser
Identification and characterization of a novel translational repressor of the steroid-inducible 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni.
The Journal of biological chemistry 2003;278(48):47400-7.
2003: Andreas Blum; Andre Raum; Edmund Maser
Functional characterization of the human 11 beta-hydroxysteroid dehydrogenase 1B (11 beta-HSD 1B) variant.
Biochemistry 2003;42(14):4108-17.
2003: Andreas Blum; Edmund Maser
The critical role of the N-terminus of 11beta-hydroxysteroid dehydrogenase type 1, as being encoded by exon 1, for enzyme stabilization and activity.
Chemico-biological interactions 2003;143-144():469-80.
2003: Gudula Bannenberg; Hans-Jörg Martin; Iván Bélai; Edmund Maser
11beta-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone.
Chemico-biological interactions 2003;143-144():449-57.
2003: Edmund Maser; Jutta Friebertshäuser; Bernhard Völker
Purification, characterization and NNK carbonyl reductase activities of 11beta-hydroxysteroid dehydrogenase type 1 from human liver: enzyme cooperativity and significance in the detoxification of a tobacco-derived carcinogen.
Chemico-biological interactions 2003;143-144():435-48.
2003: Guangming Xiong; Hans-Jörg Martin; Edmund Maser
Characterization and recombinant expression of the translational repressor RepB of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni.
Chemico-biological interactions 2003;143-144():425-33.
2003: Guangming Xiong; Stefannie Markowetz; Edmund Maser
Regulation of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase in Comamonas testosteroni: function and relationship of two operators.
Chemico-biological interactions 2003;143-144():411-23.
2002: Dirk Skowasch; Eric Möbus; Edmund Maser
Identification of a novel Comamonas testosteroni gene encoding a steroid-inducible extradiol dioxygenase.
Biochemical and biophysical research communications 2002;294(3):560-6.
2002: Anja Möller; Claudius Malerczyk; Uwe Völker; Hubert Stöppler; Edmund Maser
Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis.
Proteomics 2002;2(6):697-705.
2002: Edmund Maser; Bernhard Völker; Jutta Friebertshäuser
11 Beta-hydroxysteroid dehydrogenase type 1 from human liver: dimerization and enzyme cooperativity support its postulated role as glucocorticoid reductase.
Biochemistry 2002;41(7):2459-65.
2001: Guangming Xiong; Edmund Maser
Regulation of the steroid-inducible 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni.
The Journal of biological chemistry 2001;276(13):9961-70.
2001: A Möller; Michael Soldan; Uwe Völker; Edmund Maser
Two-dimensional gel electrophoresis: a powerful method to elucidate cellular responses to toxic compounds.
Toxicology 2001;160(1-3):129-38.
2001: C Finckh; A Atalla; G Nagel; Benno Stinner; Edmund Maser
Expression and NNK reducing activities of carbonyl reductase and 11beta-hydroxysteroid dehydrogenase type 1 in human lung.
Chemico-biological interactions 2001;130-132(1-3):761-73.
2001: Andreas Blum; A Raum; H Martin; Edmund Maser
Human 11beta-hydroxysteroid dehydrogenase 1/carbonyl reductase: additional domains for membrane attachment?
Chemico-biological interactions 2001;130-132(1-3):749-59.
2001: A Atalla; Edmund Maser
Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta.
Chemico-biological interactions 2001;130-132(1-3):737-48.
2001: Guangming Xiong; H Martin; Andreas Blum; C Schäfers; Edmund Maser
A model on the regulation of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase expression in Comamonas testosteroni.
Chemico-biological interactions 2001;130-132(1-3):723-36.
2001: Edmund Maser; Guangming Xiong; Clemens Grimm; Ralf Ficner; Klaus Reuter
3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni: biological significance, three-dimensional structure and gene regulation.
Chemico-biological interactions 2001;130-132(1-3):707-22.
2000: Clemens Grimm; Edmund Maser; Eric Möbus; Gerhard Klebe; Klaus Reuter; Ralf Ficner
The crystal structure of 3alpha -hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni shows a novel oligomerization pattern within the short chain dehydrogenase/reductase family.
The Journal of biological chemistry 2000;275(52):41333-9.
2000: Andreas Blum; Hans-Jörg Martin; Edmund Maser
Human 11beta-hydroxysteroid dehydrogenase type 1 is enzymatically active in its nonglycosylated form.
Biochemical and biophysical research communications 2000;276(2):428-34.
2000: A Atalla; Ursula Breyer-Pfaff; Edmund Maser
Purification and characterization of oxidoreductases-catalyzing carbonyl reduction of the tobacco-specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human liver cytosol.
Xenobiotica; the fate of foreign compounds in biological systems 2000;30(8):755-69.
2000: Edmund Maser; Eric Möbus; Guangming Xiong
Functional expression, purification, and characterization of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni.
Biochemical and biophysical research communications 2000;272(2):622-8.
2000: T Iffert; Michael Soldan; A Moeller; Edmund Maser
Modulation of daunorubicin toxicity by liposomal encapsulation and use of specific inhibitors in vitro.
Toxicology 2000;144(1-3):189-95.
2000: Andreas Blum; Hans-Jörg Martin; Edmund Maser
Human 11beta-hydroxysteroid dehydrogenase 1/carbonyl reductase: recombinant expression in the yeast Pichia pastoris and Escherichia coli.
Toxicology 2000;144(1-3):113-20.
2000: Udo Oppermann; Edmund Maser
Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions.
Toxicology 2000;144(1-3):71-81.
2000: Udo Oppermann; Eric Möbus; G Nagel; Edmund Maser
Heterogeneity of 11beta-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11beta-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site.
Toxicology 2000;144(1-3):63-9.
2000: Edmund Maser; Benno Stinner; A Atalla
Carbonyl reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytosolic enzymes in human liver and lung.
Cancer letters 2000;148(2):135-44.
2000: W Ax; Michael Soldan; Lutz Koch; Edmund Maser
Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction.
Biochemical pharmacology 2000;59(3):293-300.
1999: Eric Möbus; J J Rob Hermans; Edmund Maser
Characterization of 11β-hydroxysteroid dehydrogenase activities in the renal cell line LLC-PK(1) : Evidence for a third isoform?
Endocrine 1999;11(3):301-7.
1999: Eric Möbus; JJ Rob Hermans; Edmund Maser
Characterization of 11beta-hydroxysteroid dehydrogenase activities in the renal cell line LLC-PK1: evidence for a third isoform?
Endocrine 1999;11(3):301-7.
1999: A Atalla; Edmund Maser
Carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in cytosol of mouse liver and lung.
Toxicology 1999;139(1-2):155-66.
1999: Michael Soldan; G Nagel; M Losekam; M Ernst; Edmund Maser
Interindividual variability in the expression and NNK carbonyl reductase activity of 11beta-hydroxysteroid dehydrogenase 1 in human lung.
Cancer letters 1999;145(1-2):49-56.
1999: Lutz Koch; Edmund Maser; Michael Soldan
Alterations in the expression of daunorubicin phase-I metabolising enzymes in different carcinoma cell lines.
Advances in experimental medicine and biology 1999;463():545-51.
1999: Michael Soldan; W Ax; M Plebuch; Lutz Koch; Edmund Maser
Cytostatic drug resistance. Role of phase-I daunorubicin metabolism in cancer cells.
Advances in experimental medicine and biology 1999;463():529-38.
1999: Eric Möbus; Edmund Maser
Cloning and sequencing of a new Comamonas testosteroni gene encoding 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase.
Advances in experimental medicine and biology 1999;463():395-402.
1999: Edmund Maser
The protective role of 11 beta-hydroxysteroid dehydrogenase/carbonyl reductase against tobacco-smoke related lung cancer.
Advances in experimental medicine and biology 1999;463():379-87.
1998: Eric Möbus; Edmund Maser
Molecular cloning, overexpression, and characterization of steroid-inducible 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase from Comamonas testosteroni. A novel member of the short-chain dehydrogenase/reductase superfamily.
The Journal of biological chemistry 1998;273(47):30888-96.
1998: Udo Oppermann; G Nagel; I Belai; J E Bueld; S Genti-Raimondi; J Koolman; K J Netter; Edmund Maser
Carbonyl reduction of an anti-insect agent imidazole analogue of metyrapone in soil bacteria, invertebrate and vertebrate species.
Chemico-biological interactions 1998;114(3):211-24.
1998: Edmund Maser
11Beta-hydroxysteroid dehydrogenase responsible for carbonyl reduction of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes.
Cancer research 1998;58(14):2996-3003.
1997: Edmund Maser; Udo Oppermann
Role of type-1 11beta-hydroxysteroid dehydrogenase in detoxification processes.
European journal of biochemistry / FEBS 1997;249(2):365-9.
1997: Eric Möbus; M Jahn; R Schmid; Dieter Jahn; Edmund Maser
Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.
Journal of bacteriology 1997;179(18):5951-5.
1997: Edmund Maser
Stress, hormonal changes, alcohol, food constituents and drugs: factors that advance the incidence of tobacco smoke-related cancer?
Trends in pharmacological sciences 1997;18(8):270-5.
1997: D Pröpper; Edmund Maser
Carbonyl reduction of daunorubicin in rabbit liver and heart.
Pharmacology & toxicology 1997;80(5):240-5.
1997: T Niepel; Edmund Maser; JJ Rob Hermans
The effect of amiloride and sodium chloride on rat renal and hepatic 11 beta-hydroxysteroid dehydrogenase activities.
Pharmacology & toxicology 1997;80(3):127-31.
1997: Michael Soldan; Edmund Maser
Metabolic inactivation and efflux of daunorubicin as complementary mechanisms in tumor cell resistance.
Advances in experimental medicine and biology 1997;414():537-44.
1996: Eleni A Rekka; Michael Soldan; I Belai; K J Netter; Edmund Maser
Biotransformation and detoxification of insecticidal metyrapone analogues by carbonyl reduction in the human liver.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(12):1221-9.
1996: Udo Oppermann; Edmund Maser
Characterization of a 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase from the gram-negative bacterium Comamonas testosteroni.
European journal of biochemistry / FEBS 1996;241(3):744-9.
1996: Edmund Maser; E Richter; J Friebertshäuser
The identification of 11 beta-hydroxysteroid dehydrogenase as carbonyl reductase of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
European journal of biochemistry / FEBS 1996;238(2):484-9.
1996: Udo Oppermann; I Belai; Edmund Maser
Antibiotic resistance and enhanced insecticide catabolism as consequences of steroid induction in the gram-negative bacterium Comamonas testosteroni.
The Journal of steroid biochemistry and molecular biology 1996;58(2):217-23.
1996: Michael Soldan; K J Netter; Edmund Maser
Induction of daunorubicin carbonyl reducing enzymes by daunorubicin in sensitive and resistant pancreas carcinoma cells.
Biochemical pharmacology 1996;51(2):117-23.
1995: JJ Rob Hermans; B Steckel; Henk H W Thijssen; B J Janssen; K J Netter; Edmund Maser
Comparison of 11 beta-hydroxysteroid dehydrogenase in spontaneously hypertensive and Wistar-Kyoto rats.
Steroids 1995;60(11):773-9.
1995: Edmund Maser
Xenobiotic carbonyl reduction and physiological steroid oxidoreduction. The pluripotency of several hydroxysteroid dehydrogenases.
Biochemical pharmacology 1995;49(4):421-40.
1995: Udo Oppermann; K J Netter; Edmund Maser
Cloning and primary structure of murine 11 beta-hydroxysteroid dehydrogenase/microsomal carbonyl reductase.
European journal of biochemistry / FEBS 1995;227(1-2):202-8.
1995: Edmund Maser; Udo Oppermann
Molecular cloning and sequencing of mouse hepatic 11 beta-hydroxysteroid dehydrogenase/carbonyl reductase. A member of the short chain dehydrogenase superfamily.
Advances in experimental medicine and biology 1995;372():211-21.
1994: Edmund Maser; G Bannenberg
11 beta-hydroxysteroid dehydrogenase mediates reductive metabolism of xenobiotic carbonyl compounds.
Biochemical pharmacology 1994;47(10):1805-12.
1994: Edmund Maser; J Friebertshäuser; S A Mangoura
Ontogenic pattern of carbonyl reductase activity of 11 beta-hydroxysteroid dehydrogenase in mouse liver and kidney.
Xenobiotica; the fate of foreign compounds in biological systems 1994;24(2):109-17.
1994: Edmund Maser; G Bannenberg
The purification of 11 beta-hydroxysteroid dehydrogenase from mouse liver microsomes.
The Journal of steroid biochemistry and molecular biology 1994;48(2-3):257-63.
1993: C T Oppermann; K J Netter; Edmund Maser
Carbonyl reduction by 3 alpha-HSD from Comamonas testosteroni--new properties and its relationship to the SCAD family.
Advances in experimental medicine and biology 1993;328():379-90.
1993: Edmund Maser
The purification and properties of a novel carbonyl reducing enzyme from mouse liver microsomes.
Advances in experimental medicine and biology 1993;328():339-50.
1992: T Ahlers; Hans-Peter Bode; K J Netter; Edmund Maser
A novel membrane associated carbonyl reducing enzyme is present in smooth endoplasmic reticulum of mouse liver.
Biochemical and biophysical research communications 1992;189(2):736-42.
1992: Udo Oppermann; Edmund Maser; JJ Rob Hermans; J Koolman; K J Netter
Homologies between enzymes involved in steroid and xenobiotic carbonyl reduction in vertebrates, invertebrates and procaryonts.
The Journal of steroid biochemistry and molecular biology 1992;43(7):665-75.
1992: T Gebel; Edmund Maser
Characterization of carbonyl reducing activity in continuous cell lines of human and rodent origin.
Biochemical pharmacology 1992;44(10):2005-12.
1992: Edmund Maser; J G Hoffmann; J Friebertshäuser; K J Netter
High carbonyl reductase activity in adrenal gland and ovary emphasizes its role in carbonyl compound detoxication.
Toxicology 1992;74(1):45-56.
1992: Edmund Maser; Udo Oppermann; G Bannenberg; K J Netter
Functional and immunological relationships between metyrapone reductase from mouse liver microsomes and 3 alpha-hydroxysteroid dehydrogenase from Pseudomonas testosteroni.
FEBS letters 1992;297(1-2):196-200.
1991: Udo Oppermann; Edmund Maser; S A Mangoura; K J Netter
Heterogeneity of carbonyl reduction in subcellular fractions and different organs in rodents.
Biochemical pharmacology 1991;42 Suppl():S189-95.
1991: Edmund Maser; T Gebel; K J Netter
Carbonyl reduction of metyrapone in human liver.
Biochemical pharmacology 1991;42 Suppl():S93-8.
1991: Edmund Maser; K J Netter
Reductive metabolism of metyrapone by a quercitrin-sensitive ketone reductase in mouse liver cytosol.
Biochemical pharmacology 1991;41(11):1595-9.
1991: T Gebel; Edmund Maser; K J Netter
The occurrence of carbonyl reduction in continuous cell lines emphasizes the essentiality of this metabolic pathway.
FEBS letters 1991;282(2):359-62.
1991: Edmund Maser; B Hahnemann; W Legrum; Udo Oppermann; K J Netter
The influence of cytochrome P-450 inducers on carbonyl reduction in mouse liver.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1991;14():188-92.
1989: Edmund Maser; K J Netter
Purification and properties of a metyrapone-reducing enzyme from mouse liver microsomes--this ketone is reduced by an aldehyde reductase.
Biochemical pharmacology 1989;38(18):3049-54.
1989: Edmund Maser
Characterization of microsomal and cytoplasmic metyrapone reducing enzymes from mouse liver.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():271-4.
1987: M Brüch; L Kling; W Legrum; Edmund Maser
The 14CO2 breath test: facilities and limitations of a rapid and noninvasive method for in vivo evaluation of modified hepatic cytochrome P-450--a critique.
Archives of toxicology 1987;60(1-3):81-5.
1985: Edmund Maser; W Legrum
Alteration of the inhibitory effect of metyrapone by reduction to metyrapol during the metabolism of methacetin in vivo in mice.
Naunyn-Schmiedeberg's archives of pharmacology 1985;331(2-3):283-9.