FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Silvio Massa

Research Profile

Chemicals & Drugs

Concepts & Ideas

Living Beings

HIV-1
Mouse

Procedures

Microbial Sensitivity Tests

Phenomena

Occupations

Anatomy

Cell Line

Co-author Network

Publications

TOP 3
Cristina Tintori; Frauke Christ; zeger debyser; Jonas Demeulemeester; Luigi Franchi; Silvio Massa; Maurizio Botta
Discovery of small molecule HIV-1 integrase dimerization inhibitors.
Sergio Valente; Maria Tardugno; Mariarosaria Conte; Roberto Cirilli; Andrea Perrone; Rino Ragno; Silvia Simeoni; Anna Tramontano; Silvio Massa; Angela Nebbioso; Marco Miceli; Gianluigi Franci; Gerald Brosch; Lucia Altucci; Antonello Mai
Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity.
Marta Rinaldi; Cristina Tintori; Luigi Franchi; Giulia Vignaroli; Anna Innitzer; Silvio Massa; José A Esté; Encarna Gonzalo; Frauke Christ; zeger debyser; Maurizio Botta
A versatile and practical synthesis toward the development of novel HIV-1 integrase inhibitors.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Silvio Massa (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Cristina Tintori; Frauke Christ; zeger debyser; Jonas Demeulemeester; Luigi Franchi; Silvio Massa; Maurizio Botta
Discovery of small molecule HIV-1 integrase dimerization inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(9):3109-14.
2011: Sergio Valente; Maria Tardugno; Mariarosaria Conte; Roberto Cirilli; Andrea Perrone; Rino Ragno; Silvia Simeoni; Anna Tramontano; Silvio Massa; Angela Nebbioso; Marco Miceli; Gianluigi Franci; Gerald Brosch; Lucia Altucci; Antonello Mai
Novel cinnamyl hydroxyamides and 2-aminoanilides as histone deacetylase inhibitors: apoptotic induction and cytodifferentiation activity.
ChemMedChem 2011;6(4):698-712.
2011: Marta Rinaldi; Cristina Tintori; Luigi Franchi; Giulia Vignaroli; Anna Innitzer; Silvio Massa; José A Esté; Encarna Gonzalo; Frauke Christ; zeger debyser; Maurizio Botta
A versatile and practical synthesis toward the development of novel HIV-1 integrase inhibitors.
ChemMedChem 2011;6(2):343-52.
2009: Sergio Valente; Mariarosaria Conte; Maria Tardugno; Silvio Massa; Angela Nebbioso; Lucia Altucci; Antonello Mai
Pyrrole-based hydroxamates and 2-aminoanilides: histone deacetylase inhibition and cellular activities.
ChemMedChem 2009;4(9):1411-5.
2009: Suvi Rajamaki; Anna Innitzer; Chiara Falciani; Cristina Tintori; Frauke Christ; Myriam Witvrouw; zeger debyser; Silvio Massa; Maurizio Botta
Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(13):3615-8.
2009: Antonello Mai; Sergio Valente; Angela Nebbioso; Silvia Simeoni; Rino Ragno; Silvio Massa; Gerald Brosch; Floriana De Bellis; Fabio Manzo; Lucia Altucci
New pyrrole-based histone deacetylase inhibitors: binding mode, enzyme- and cell-based investigations.
The international journal of biochemistry & cell biology 2009;41(1):235-47.
2008: Antonello Mai; Andrea Perrone; Angela Nebbioso; Dante Rotili; Sergio Valente; Maria Tardugno; Silvio Massa; Floriana De Bellis; Lucia Altucci
Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities.
Bioorganic & medicinal chemistry letters 2008;18(8):2530-5.
2008: Rino Ragno; Silvia Simeoni; Dante Rotili; Antonella Caroli; Giorgia Botta; Gerald Brosch; Silvio Massa; Antonello Mai
Class II-selective histone deacetylase inhibitors. Part 2: alignment-independent GRIND 3-D QSAR, homology and docking studies.
European journal of medicinal chemistry 2008;43(3):621-32.
2007: Claudia Mugnaini; Maddalena Alongi; Andrea Togninelli; Harsukh Gevariya; Antonella Brizzi; Fabrizio Manetti; Cesare Bernardini; Lucilla Angeli; Andrea Tafi; Luca Bellucci; Federico Corelli; Silvio Massa; giovanni maga; Alberta Samuele; Marcella Facchini; Imma Clotet-Codina; Mercedes Armand-Ugón; José A Esté; Maurizio Botta
Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.
Journal of medicinal chemistry 2007;50(26):6580-95.
2007: Antonello Mai; Katija Jelicic; Dante Rotili; Antonella Di Noia; Elena Alfani; Sergio Valente; Lucia Altucci; Angela Nebbioso; Silvio Massa; Renzo Galanello; Gerald Brosch; Anna Rita Migliaccio; Giovanni Migliaccio
Identification of two new synthetic histone deacetylase inhibitors that modulate globin gene expression in erythroid cells from healthy donors and patients with thalassemia.
Molecular pharmacology 2007;72(5):1111-23.
2007: Claudia Mugnaini; Suvi Rajamaki; Cristina Tintori; Federico Corelli; Silvio Massa; Myriam Witvrouw; zeger debyser; veljko veljkovic; Maurizio Botta
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.
Bioorganic & medicinal chemistry letters 2007;17(19):5370-3.
2007: Marco Radi; Lorenzo Contemori; Daniele Castagnolo; Raffaella Spinosa; José A Esté; Silvio Massa; Maurizio Botta
A versatile route to C-6 arylmethyl-functionalized S-DABO and related analogues.
Organic letters 2007;9(16):3157-60.
2007: Cristina Tintori; Fabrizio Manetti; Nevena Veljkovic; Vladimir Perovic; Jo Vercammen; Sean Hayes; Silvio Massa; Myriam Witvrouw; zeger debyser; veljko veljkovic; Maurizio Botta
Novel virtual screening protocol based on the combined use of molecular modeling and electron-ion interaction potential techniques to design HIV-1 integrase inhibitors.
Journal of chemical information and modeling 2007;47(4):1536-44.
2007: Antonello Mai; Dante Rotili; Silvio Massa; Gerald Brosch; Giovanna Simonetti; Claudio Passariello; Anna Teresa Palamara
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans.
Bioorganic & medicinal chemistry letters 2007;17(5):1221-5.
2007: Antonello Mai; Sergio Valente; Dante Rotili; Silvio Massa; Giorgia Botta; Gerald Brosch; Marco Miceli; Angela Nebbioso; Lucia Altucci
Novel pyrrole-containing histone deacetylase inhibitors endowed with cytodifferentiation activity.
The international journal of biochemistry & cell biology 2007;39(7-8):1510-22.
2006: Antonello Mai; Silvio Massa; Dante Rotili; Silvia Simeoni; Rino Ragno; Giorgia Botta; Angela Nebbioso; Marco Miceli; Lucia Altucci; Gerald Brosch
Synthesis and biological properties of novel, uracil-containing histone deacetylase inhibitors.
Journal of medicinal chemistry 2006;49(20):6046-56.
2006: Rino Ragno; Silvia Simeoni; Sergio Valente; Silvio Massa; Antonello Mai
3-D QSAR studies on histone deacetylase inhibitors. A GOLPE/GRID approach on different series of compounds.
Journal of chemical information and modeling 2006;46(3):1420-30.
2006: Fabrizio Manetti; Cristina Tintori; Mercedes Armand-Ugón; Imma Clotet-Codina; Silvio Massa; Rino Ragno; José A Esté; Maurizio Botta
A combination of molecular dynamics and docking calculations to explore the binding mode of ADS-J1, a polyanionic compound endowed with anti-HIV-1 activity.
Journal of chemical information and modeling 2006;46(3):1344-51.
2006: Antonello Mai; Silvio Massa; Sergio Valente; Silvia Simeoni; Rino Ragno; Patrizia Bottoni; Roberto Scatena; Gerald Brosch
Aroyl-pyrrolyl hydroxyamides: influence of pyrrole C4-phenylacetyl substitution on histone deacetylase inhibition.
ChemMedChem 2006;1(2):225-37.
2005: Fabrizio Manetti; José A Esté; Imma Clotet-Codina; Mercedes Armand-Ugón; giovanni maga; Emmanuele Crespan; Reynel Cancio; Claudia Mugnaini; Cesare Bernardini; Andrea Togninelli; Caterina Carmi; Maddalena Alongi; Elena Petricci; Silvio Massa; Federico Corelli; Maurizio Botta
Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.
Journal of medicinal chemistry 2005;48(25):8000-8.
2005: Antonello Mai; Silvio Massa; Siva Lavu; Riccardo Pezzi; Silvia Simeoni; Rino Ragno; Francesca Romana Mariotti; Francesco Chiani; Giorgio Camilloni; David A Sinclair
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.
Journal of medicinal chemistry 2005;48(24):7789-95.
2005: Antonello Mai; Silvio Massa; Dante Rotili; Riccardo Pezzi; Patrizia Bottoni; Roberto Scatena; Joachim Meraner; Gerald Brosch
Exploring the connection unit in the HDAC inhibitor pharmacophore model: novel uracil-based hydroxamates.
Bioorganic & medicinal chemistry letters 2005;15(21):4656-61.
2005: Antonello Mai; Silvio Massa; Riccardo Pezzi; Silvia Simeoni; Dante Rotili; Angela Nebbioso; Annamaria Scognamiglio; Lucia Altucci; Peter Loidl; Gerald Brosch
Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.
Journal of medicinal chemistry 2005;48(9):3344-53.
2005: Antonello Mai; Silvio Massa; Riccardo Pezzi; Sergio Valente; Peter Loidl; Gerald Brosch
Synthesis and biological evaluation of 2-, 3-, and 4-acylaminocinnamyl-N-hydroxyamides as novel synthetic HDAC inhibitors.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2005;1(3):245-54.
2005: Antonello Mai; Silvio Massa; Dante Rotili; Ilaria Cerbara; Sergio Valente; Riccardo Pezzi; Silvia Simeoni; Rino Ragno
Histone deacetylation in epigenetics: an attractive target for anticancer therapy.
Medicinal research reviews 2005;25(3):261-309.
2005: Antonello Mai; Marino Artico; Rino Ragno; Gianluca Sbardella; Silvio Massa; Chiara Musiu; Massimo Mura; Flavia Marturana; Alessandra Cadeddu; giovanni maga; Paolo La Colla
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Bioorganic & medicinal chemistry 2005;13(6):2065-77.
2005: Rino Ragno; Simona Frasca; Fabrizio Manetti; Antonella Brizzi; Silvio Massa
HIV-reverse transcriptase inhibition: inclusion of ligand-induced fit by cross-docking studies.
Journal of medicinal chemistry 2005;48(1):200-12.
2004: Roberta Costi; Roberto Di Santo; Marino Artico; Alessandra Roux; Rino Ragno; Silvio Massa; Enzo Tramontano; Massimiliano La Colla; Roberta Loddo; Maria Elena Marongiu; Alessandra Pani; Paolo La Colla
6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays.
Bioorganic & medicinal chemistry letters 2004;14(7):1745-9.
2004: Antonello Mai; Ilaria Cerbara; Sergio Valente; Silvio Massa; Larry Walker; Babu L Tekwani
Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors.
Antimicrobial agents and chemotherapy 2004;48(4):1435-6.
2004: Rino Ragno; Antonello Mai; Silvio Massa; Ilaria Cerbara; Sergio Valente; Patrizia Bottoni; Roberto Scatena; Florian Jesacher; Peter Loidl; Gerald Brosch
3-(4-Aroyl-1-methyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 3. Discovery of novel lead compounds through structure-based drug design and docking studies.
Journal of medicinal chemistry 2004;47(6):1351-9.
2004: Antonello Mai; Silvio Massa; Ilaria Cerbara; Sergio Valente; Rino Ragno; Patrizia Bottoni; Roberto Scatena; Peter Loidl; Gerald Brosch
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.
Journal of medicinal chemistry 2004;47(5):1098-109.
2004: Rino Ragno; Antonello Mai; Gianluca Sbardella; Marino Artico; Silvio Massa; Chiara Musiu; Massimo Mura; Flavia Marturana; Alessandra Cadeddu; Paolo La Colla
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C variant.
Journal of medicinal chemistry 2004;47(4):928-34.
2004: Roberta Costi; Roberto Di Santo; Marino Artico; Silvio Massa; Rino Ragno; Roberta Loddo; Massimiliano La Colla; Enzo Tramontano; Paolo La Colla; Alessandra Pani
2,6-Bis(3,4,5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays.
Bioorganic & medicinal chemistry 2004;12(1):199-215.
2003: Antonello Mai; Silvio Massa; Riccardo Pezzi; Dante Rotili; Peter Loidl; Gerald Brosch
Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A.
Journal of medicinal chemistry 2003;46(23):4826-9.
2003: Romano Silvestri; Gabriella De Martino; Giuseppe La Regina; Marino Artico; Silvio Massa; Laura Vargiu; Massimo Mura; Anna Giulia Loi; Tiziana Marceddu; Paolo La Colla
Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.
Journal of medicinal chemistry 2003;46(12):2482-93.
2003: Antonello Mai; Marino Artico; Monica Esposito; Rino Ragno; Gianluca Sbardella; Silvio Massa
Synthesis and biological evaluation of enantiomerically pure pyrrolyl-oxazolidinones as a new class of potent and selective monoamine oxidase type A inhibitors.
Farmaco (Società chimica italiana : 1989) 2003;58(3):231-41.
2003: Antonello Mai; Silvio Massa; Rino Ragno; Ilaria Cerbara; Florian Jesacher; Peter Loidl; Gerald Brosch
3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. 1. Design, synthesis, biological evaluation, and binding mode studies performed through three different docking procedures.
Journal of medicinal chemistry 2003;46(4):512-24.
2002: Roberto Di Santo; Roberta Costi; Marino Artico; Silvio Massa; Rino Ragno; Garland R Marshall; Paolo La Colla
Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors.
Bioorganic & medicinal chemistry 2002;10(8):2511-26.
2002: Andrea Tafi; Roberta Costi; Maurizio Botta; Roberto Di Santo; Federico Corelli; Silvio Massa; Andrea Ciacci; Fabrizio Manetti; Marino Artico
Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies.
Journal of medicinal chemistry 2002;45(13):2720-32.
2002: Antonello Mai; Silvio Massa; Rino Ragno; Monica Esposito; Gianluca Sbardella; Giuseppina Nocca; Roberto Scatena; Florian Jesacher; Peter Loidl; Gerald Brosch
Binding mode analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation.
Journal of medicinal chemistry 2002;45(9):1778-84.
2002: Romano Silvestri; Marino Artico; Gabriella De Martino; Rino Ragno; Silvio Massa; Roberta Loddo; Chiara Murgioni; Anna Giulia Loi; Paolo La Colla; Alessandra Pani
Synthesis, biological evaluation, and binding mode of novel 1-[2-(diarylmethoxy)ethyl]-2-methyl-5-nitroimidazoles targeted at the HIV-1 reverse transcriptase.
Journal of medicinal chemistry 2002;45(8):1567-76.
2002: Antonello Mai; Marino Artico; Monica Esposito; Gianluca Sbardella; Silvio Massa; Olivia Befani; Paola Turini; Valentina Giovannini; Bruno Mondovì
3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A.
Journal of medicinal chemistry 2002;45(6):1180-3.
2001: Antonello Mai; Gianluca Sbardella; Marino Artico; Rino Ragno; Silvio Massa; Ettore Novellino; G Greco; Antonio Lavecchia; Chiara Musiu; Massimiliano La Colla; Chiara Murgioni; Paolo La Colla; Roberta Loddo
Structure-based design, synthesis, and biological evaluation of conformationally restricted novel 2-alkylthio-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Journal of medicinal chemistry 2001;44(16):2544-54.
2001: Silvio Massa; Antonello Mai; Gianluca Sbardella; M Esposito; Rino Ragno; Peter Loidl; Gerald Brosch
3-(4-aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors.
Journal of medicinal chemistry 2001;44(13):2069-72.
2001: Maria Giovanna Quaglia; Antonello Mai; Gianluca Sbardella; Marino Artico; Rino Ragno; Silvio Massa; D del Piano; G Setzu; S Doratiotto; V Cotichini
Chiral resolution and molecular modeling investigation of rac-2-cyclopentylthio-6-[1-(2,6-difluorophenyl)ethyl]-3,4-dihydro-5-methylpyrimidin-4(3H)-one (MC-1047), a potent anti-HIV-1 reverse transcriptase agent of the DABO class.
Chirality 2001;13(2):75-80.
2001: Gianluca Sbardella; Antonello Mai; Marino Artico; Paola Chimenti; Silvio Massa; Roberta Loddo; Maria Elena Marongiu; P La Collat; Alessandra Pani
Structure-activity relationship studies on new DABOS: effect of substitutions at pyrimidine C-5 and C-6 positions on anti-HIV-1 activity.
Antiviral chemistry & chemotherapy 2001;12(1):37-50.
2000: Romano Silvestri; Marino Artico; Gabriella De Martino; Ettore Novellino; G Greco; Antonio Lavecchia; Silvio Massa; Anna Giulia Loi; S Doratiotto; Paolo La Colla
Computer-assisted design, synthesis and biological evaluation of novel pyrrolyl heteroaryl sulfones targeted at HIV-1 reverse transcriptase as non-nucleoside inhibitors.
Bioorganic & medicinal chemistry 2000;8(9):2305-9.
2000: Rino Ragno; Garland R Marshall; Roberto Di Santo; Roberta Costi; Silvio Massa; R Rompei; M Artico
Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies.
Bioorganic & medicinal chemistry 2000;8(6):1423-32.
2000: Marino Artico; Romano Silvestri; E Pagnozzi; B Bruno; Ettore Novellino; G Greco; Silvio Massa; A Ettorre; Anna Giulia Loi; F Scintu; Paolo La Colla
Structure-based design, synthesis, and biological evaluation of novel pyrrolyl aryl sulfones: HIV-1 non-nucleoside reverse transcriptase inhibitors active at nanomolar concentrations.
Journal of medicinal chemistry 2000;43(9):1886-91.
2000: Roberta Costi; Roberto Di Santo; Marino Artico; Silvio Massa; Antonio Lavecchia; Tiziana Marceddu; L Sanna; Paolo La Colla; Maria Elena Marongiu
Structure-activity relationship studies on potential non-nucleoside DABO-like inhibitors of HIV-1 reverse transcriptase.
Antiviral chemistry & chemotherapy 2000;11(2):117-33.
2000: Romano Silvestri; Marino Artico; Silvio Massa; Tiziana Marceddu; F De Montis; Paolo La Colla
1-[2-(Diphenylmethoxy)ethyl]-2-methyl-5-nitroimidazole: a potent lead for the design of novel NNRTIs.
Bioorganic & medicinal chemistry letters 2000;10(3):253-6.
1999: Marino Artico; Antonello Mai; Gianluca Sbardella; Silvio Massa; Chiara Musiu; S Lostia; F Demontis; Paolo La Colla
Nitroquinolones with broad-spectrum antimycobacterial activity in vitro.
Bioorganic & medicinal chemistry letters 1999;9(12):1651-6.
1999: Antonello Mai; Marino Artico; Gianluca Sbardella; Silvio Massa; Ettore Novellino; G Greco; Anna Giulia Loi; Enzo Tramontano; Maria Elena Marongiu; Paolo La Colla
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3, 4-dihydropyrimidin-4(3H)-ones: novel potent and selective dihydro-alkoxy-benzyl-oxopyrimidine derivatives.
Journal of medicinal chemistry 1999;42(4):619-27.
1998: Roberto Di Santo; Roberta Costi; Marino Artico; Silvio Massa; Giorgio Lampis; Delia Deidda; Raffaello Pompei
Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 1998;8(20):2931-6.
1998: Marino Artico; Roberto Di Santo; Roberta Costi; Ettore Novellino; G Greco; Silvio Massa; Enzo Tramontano; Maria Elena Marongiu; A De Montis; Paolo La Colla
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling.
Journal of medicinal chemistry 1998;41(21):3948-60.
1998: Marino Artico; Antonello Mai; Gianluca Sbardella; Silvio Massa; Giorgio Lampis; Delia Deidda; Raffaello Pompei
N-[4-(1,1'-biphenyl)methyl]-4-(4-thiomorpholinylmethyl) benzenamines as non-oxazolidinone analogues of antimycobacterial U-100480.
Bioorganic & medicinal chemistry letters 1998;8(12):1493-8.
1998: Romano Silvestri; Marino Artico; B Bruno; Silvio Massa; Ettore Novellino; G Greco; Maria Elena Marongiu; Alessandra Pani; A De Montis; Paolo La Colla
Synthesis and biological evaluation of 5H-indolo [3,2-b][1,5]benzothiazepine derivatives, designed as conformationally constrained analogues of the human immunodeficiency virus type 1 reverse transcriptase inhibitor L-737,126.
Antiviral chemistry & chemotherapy 1998;9(2):139-48.
1998: Roberto Di Santo; Roberta Costi; Marino Artico; Silvio Massa; Maria Elena Marongiu; Anna Giulia Loi; A De Montis; Paolo La Colla
1,2,5-Benzothiadiazepine and pyrrolo[2,1-d]-[1,2,5]benzothiadiazepine derivatives with specific anti-human immunodeficiency virus type 1 activity.
Antiviral chemistry & chemotherapy 1998;9(2):127-37.
1997: Roberto Di Santo; Roberta Costi; Marino Artico; Silvio Massa
Heterocycles with a benzothiadiazepine moiety. 5. Derivatives of pyrrolo[2,1-d][1,2,5]benzothiadiazepine, a novel tricyclic ring.
Farmaco (Società chimica italiana : 1989) 1997;52(6-7):375-8.
1997: Antonello Mai; Marino Artico; Gianluca Sbardella; S Quartarone; Silvio Massa; Anna Giulia Loi; A De Montis; F Scintu; Marirosa Putzolu; Paolo La Colla
Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: novel non-nucleoside reverse transcriptase inhibitors of the S-DABO series.
Journal of medicinal chemistry 1997;40(10):1447-54.
1997: Romano Silvestri; Marino Artico; Silvio Massa; Giorgio Stefancich; Elena Congeddu; Marirosa Putzolu; Paolo La Colla
Sulfone derivatives with anti-HIV activity.
Farmaco (Società chimica italiana : 1989) 1997;52(5):323-9.
1996: Marino Artico; Maurizio Botta; Federico Corelli; Antonello Mai; Silvio Massa; Rino Ragno
Investigation on QSAR and binding mode of a new class of human rhinovirus-14 inhibitors by CoMFA and docking experiments.
Bioorganic & medicinal chemistry 1996;4(10):1715-24.
1996: Marino Artico; Romano Silvestri; E Pagnozzi; G Stefancich; Silvio Massa; Anna Giulia Loi; Marirosa Putzolu; S Corrias; M. Grazia Spiga; Paolo La Colla
5H-pyrrolo[1,2-b] [1,2,5]benzothiadiazepines (PBTDs): a novel class of non-nucleoside reverse transcriptase inhibitors.
Bioorganic & medicinal chemistry 1996;4(6):837-50.
1996: Romano Silvestri; Marino Artico; E Pagnozzi; G Stefancich; Silvio Massa; Paolo La Colla; Anna Giulia Loi; M. Grazia Spiga; S Corrias; D Lichino
Synthesis and anti-HIV activity of 10,11-dihydropyrrolo [1,2-b][1,2,5]benzothiadiazepine-11-acetic acid 5,5-dioxide derivatives and related compounds.
Farmaco (Società chimica italiana : 1989) 1996;51(6):425-30.
1996: Andrea Tafi; J Anastassopoulou; T Theophanides; Maurizio Botta; Federico Corelli; Silvio Massa; Marino Artico; Roberta Costi; Roberto Di Santo; Rino Ragno
Molecular modeling of azole antifungal agents active against Candida albicans. 1. A comparative molecular field analysis study.
Journal of medicinal chemistry 1996;39(6):1227-35.
1996: Marino Artico; Romano Silvestri; Silvio Massa; Anna Giulia Loi; S Corrias; G Piras; Paolo La Colla
2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.
Journal of medicinal chemistry 1996;39(2):522-30.
1995: Marino Artico; Roberto Di Santo; Roberta Costi; Silvio Massa; A Retico; M Artico; G Apuzzo; G Simonetti; V Strippoli
Antifungal agents. 9. 3-Aryl-4-[alpha-(1H-imidazol-1-yl)arylmethyl]pyrroles: a new class of potent anti-Candida agents.
Journal of medicinal chemistry 1995;38(21):4223-33.
1995: Antonello Mai; Marino Artico; Gianluca Sbardella; Silvio Massa; Anna Giulia Loi; Enzo Tramontano; P Scano; Paolo La Colla
Synthesis and anti-HIV-1 activity of thio analogues of dihydroalkoxybenzyloxopyrimidines.
Journal of medicinal chemistry 1995;38(17):3258-63.
1995: Romano Silvestri; E Pagnozzi; F Troccoli; G Stefancich; Silvio Massa; G Apuzzo; M E Perazzi; Marino Artico; G Simonetti
Antifungal agents. 10. Synthesis and antifungal activities of aryl-(1H-imidazol-1-yl)-(isoquinolin-1-yl) methane derivatives.
Farmaco (Società chimica italiana : 1989) 1995;50(4):227-38.
1995: Silvio Massa; Federico Corelli; Marino Artico; Antonello Mai; Rino Ragno; A De Montis; Anna Giulia Loi; S Corrias; Maria Elena Marongiu; Paolo La Colla
[[[(Thienylcarbonyl)alkyl]oxy]phenyl]- and [[[(pyrrylcarbonyl)alkyl]oxy]phenyl]oxazoline derivatives with potent and selective antihuman rhinovirus activity.
Journal of medicinal chemistry 1995;38(5):803-9.
1995: Marino Artico; Romano Silvestri; G Stefancich; Silvio Massa; E Pagnozzi; D Musu; F Scintu; E Pinna; E Tinti; Paolo La Colla
Synthesis of pyrryl aryl sulfones targeted at the HIV-1 reverse transcriptase.
Archiv der Pharmazie 1995;328(3):223-9.
1994: Enzo Tramontano; Maria Elena Marongiu; A De Montis; Anna Giulia Loi; Marino Artico; Silvio Massa; Antonello Mai; Paolo La Colla
Characterization of the anti-HIV-1 activity of 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs), new non-nucleoside reverse transcriptase inhibitors.
The new microbiologica 1994;17(4):269-79.
1994: Roberto Di Santo; Silvio Massa; Roberta Costi; G Simonetti; A Retico; G Apuzzo; F Troccoli
Antifungal agents. VIII. Synthesis and antifungal activities of bipyrryl analogues of bifonazole.
Farmaco (Società chimica italiana : 1989) 1994;49(4):229-36.
1994: Silvio Massa; Antonello Mai; Rino Ragno; Giulio Cesare Porretta; A Retico; G Simonetti; Marino Artico
Antifungal agents. 7. Dichlorophenylpyrrylimidazolylmethane derivatives: synthesis and antifungal activities.
Farmaco (Società chimica italiana : 1989) 1994;49(1):51-5.
1993: Silvio Massa; Rino Ragno; Giulio Cesare Porretta; Antonello Mai; A Retico; Marino Artico; N Simonetti
Antifungal agents, II: Synthesis and antifungal activities of aryl-1H-pyrrol-2-yl-1H-imidazol-1-yl-methane derivatives with unsaturated chains.
Archiv der Pharmazie 1993;326(9):539-46.
1993: Silvio Massa; Roberto Di Santo; Roberta Costi; G Simonetti; A Retico; G Apuzzo; Marino Artico
Antifungal agents. III. Naphthyl and thienyl derivatives of 1H-imidazol-1-yl-4-phenyl-1H-pyrrol-3-ylmethane.
Farmaco (Società chimica italiana : 1989) 1993;48(6):725-36.
1992: Silvio Massa; Marino Artico; Antonello Mai; Federico Corelli; Maurizio Botta; Andrea Tafi; Giancarlo Pantaleoni; R Giorgi; M F Coppolino; Alfredo Cagnotto
Pyrrolobenzodiazepines and related systems. 2. Synthesis and biological properties of isonoraptazepine derivatives.
Journal of medicinal chemistry 1992;35(24):4533-41.
1992: Silvio Massa; Roberto Di Santo; Antonello Mai; Marino Artico; Giancarlo Pantaleoni; R Giorgi; M F Coppolino
Pyrrylphenylethanones related to cathinone and lefetamine: synthesis and pharmacological activities.
Archiv der Pharmazie 1992;325(7):403-9.
1990: Silvio Massa; Marino Artico; Antonello Mai; Federico Corelli; Giancarlo Pantaleoni; R Giorgi; D Ottaviani; Alfredo Cagnotto
Pyrrolobenzodiazepine and related systems. I. Synthesis and pharmacological evaluation of new 5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepine derivatives.
Farmaco (Società chimica italiana : 1989) 1990;45(12):1265-81.
1990: Silvio Massa; Marino Artico; Federico Corelli; Antonello Mai; Roberto Di Santo; S Cortes; Maria Elena Marongiu; Alessandra Pani; Paolo La Colla
Synthesis and antimicrobial and cytotoxic activities of pyrrole-containing analogues of trichostatin A.
Journal of medicinal chemistry 1990;33(10):2845-9.
1990: Silvio Massa; Roberto Di Santo; Antonello Mai; Maurizio Botta; Marino Artico; S Panico; G Simonetti
Research on antibacterial and antifungal agents. XIII. Synthesis and antimicrobial activity of 1-arylmethyl-4-aryl-1H-pyrrole-3-carboxylic acids.
Farmaco (Società chimica italiana : 1989) 1990;45(7-8):833-46.
1989: Silvio Massa; Federico Corelli; Antonello Mai; Marino Artico; S Panico; N Simonetti
Research on antibacterial and antifungal agents. XI. New antibacterial quinolones related to pirfloxacin.
Farmaco (Società chimica italiana : 1989) 1989;44(9):779-93.
1989: Silvio Massa; G Stefancich; Marino Artico; Federico Corelli; Romano Silvestri; Giancarlo Pantaleoni; D Fanini; G Palumbo; R Giorgi
Synthesis, neuropsychopharmacological effects and analgesic-antiinflammatory activities of pyrrole analogues of lefetamine.
Farmaco (Società chimica italiana : 1989) 1989;44(9):763-77.
1989: Silvio Massa; G Stefancich; Federico Corelli; Romano Silvestri; Antonello Mai; Marino Artico; S Panico; N Simonetti
Researches on antibacterial and antifungal agents, X. Synthesis and antifungal activities of 1-(p-methyl-alpha-[4-(1H-pyrrol-1-yl)phenyl]benzyl)azoles and some related products.
Archiv der Pharmazie 1989;322(6):369-73.
1989: Silvio Massa; Federico Corelli; Marino Artico; Antonello Mai; Romano Silvestri; Giancarlo Pantaleoni; G Palumbo; D Fanini; R Giorgi
[5-Aroyl-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepin-4-carboxylic acids: synthesis and analgesic and neurobehavioral activity].
Farmaco (Società chimica italiana : 1989) 1989;44(2):109-23.
1988: Laura Morpurgo; Olivia Befani; S Sabatini; Bruno Mondovì; Marino Artico; Federico Corelli; Silvio Massa; G Stefancich; Luciana Avigliano
Spectroscopic studies of the reaction between bovine serum amine oxidase (copper-containing) and some hydrazides and hydrazines.
The Biochemical journal 1988;256(2):565-70.
1988: Silvio Massa; G Stefancich; Federico Corelli; Romano Silvestri; S Panico; Marino Artico; N Simonetti
Researches on antibacterial and antifungal agents. IX--Pyrrole analogues of bifonazole with potent antifungal activities.
Il Farmaco; edizione scientifica 1988;43(9):693-704.
1988: Marino Artico; Federico Corelli; Silvio Massa; G Stefancich; Luciana Avigliano; Olivia Befani; Giordana Marcozzi; S Sabatini; Bruno Mondovi
Inhibition of copper-dependent amine oxidases by some hydrazides of pyrrol-1-ylbenzoic and pyrrol-1-ylphenylacetic acids.
Journal of medicinal chemistry 1988;31(4):802-6.
1988: Federico Corelli; Silvio Massa; G Stefancich; Romano Silvestri; Marino Artico; Giancarlo Pantaleoni; G Palumbo; D Fanini; R Giorgi
[Nonsteroidal anti-inflammatory agents. V. Synthesis of 1-aryl-5-(1-pyrryl)-pyrazolyl-4-acetic acids with potential anti-inflammatory action].
Il Farmaco; edizione scientifica 1988;43(3):251-65.
1987: Federico Corelli; Silvio Massa; G Stefancich; Antonello Mai; Marino Artico; S Panico; N Simonetti
[Antibacterial and antifungal compounds. VIII. Synthesis and antifungal activity of pyrrol derivatives similar to trichostatin A].
Il Farmaco; edizione scientifica 1987;42(12):893-903.
1987: Federico Corelli; Silvio Massa; G Stefancich; Marino Artico; Romano Silvestri
Potential antitumor agents. II. Lappin intramolecular cyclization of diethyl 3-carbazolylaminomethylenemalonate: a structure assignment.
Il Farmaco; edizione scientifica 1987;42(9):641-7.
1987: Silvio Massa; G Stefancich; Marino Artico; Federico Corelli; Romano Silvestri
Potential antitumor agents. I. Synthesis of pyrroloindazole derivatives related to the pyrroloindole moieties of the antitumor antibiotic CC-1065.
Il Farmaco; edizione scientifica 1987;42(8):567-74.
1987: G Stefancich; Federico Corelli; Silvio Massa; Romano Silvestri; S Panico; Marino Artico; N Simonetti
[Research on antibacterial and antifungal agents. VII. Synthesis of (1-pyrryl)methylquinolines acids].
Il Farmaco; edizione scientifica 1987;42(1):3-16.
1986: Marino Artico; Federico Corelli; Silvio Massa; G Stefancich; S Panico; N Simonetti
[Antibacterial and antifungal agents. VI. Pirfloxacin and related compounds: synthetic and microbiological studies].
Il Farmaco; edizione scientifica 1986;41(5):366-80.
1986: Silvio Massa; G Stefancich; Marino Artico; Federico Corelli; Giancarlo Pantaleoni; G Palumbo; D Fanini; R Giorgi
[Non-steroidal anti-inflammatory agents. IV. Synthesis and pharmacologic activity of aroylthiopheneacetic acids with a pyrrole group].
Il Farmaco; edizione scientifica 1986;41(4):281-91.
1985: G Stefancich; Marino Artico; Federico Corelli; Silvio Massa; Giancarlo Pantaleoni; G Palumbo; D Fanini; R Giorgi
[New psychotropic agents. 2. Synthesis and pharmacologic activity of derivatives of 5H-pyrrolo[1,2-b][1,2,5]benzotriazepines].
Il Farmaco; edizione scientifica 1985;40(12):930-41.
1985: Federico Corelli; Silvio Massa; G Stefancich; Marino Artico; S Panico; N Simonetti
[Antibacterial and antifungal compounds. V. Synthesis and antimicrobial activity of N-(2-arylethylaminophenyl)-1H-pyrryl-1-amine and 1-(1H-pyrrol-1-yl)-2-arylmethylbenzimidazole)].
Il Farmaco; edizione scientifica 1985;40(7):501-8.
1985: Federico Corelli; Silvio Massa; G Stefancich; G Ortenzi; V Strippoli; Marino Artico; N Simonetti
[Antibacterial and antifungal agents. IV. Synthesis and antifungal activity of econazole analogs with pyrrole structure].
Il Farmaco; edizione scientifica 1985;40(5):315-24.
1985: G Stefancich; Marino Artico; Federico Corelli; Silvio Massa; S Panico; N Simonetti
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1H-pyrrol-1-yl)-quinoline-3-carb oxylic acid, a new fluorinated compounds of oxacin family with high broad-spectrum antibacterial activities.
Il Farmaco; edizione scientifica 1985;40(4):237-48.
1984: Marino Artico; Federico Corelli; Silvio Massa; G Stefancich; S Panico; N Simonetti
Research on antibacterial and antifungal agents. III. Synthesis of 1-ethyl-1,4-dihydro-4-oxo-7-(1-pyrryl)quinoline-3-carboxylic acid and of some 6-derivatives.
Il Farmaco; edizione scientifica 1984;39(11):910-24.
1984: G Stefancich; Marino Artico; Federico Corelli; Silvio Massa; Giancarlo Pantaleoni; G Palumbo; D Fanini; G Giorgi
[Non-steroidal anti-inflammatory agents. III. Synthesis and analgesic-anti-inflammatory activity of 4-(pyrrol-1-yl)phenylacetamides and 4-(pyrrol-1-yl)phenethylamines].
Il Farmaco; edizione scientifica 1984;39(9):752-64.
1984: Federico Corelli; Silvio Massa; Giancarlo Pantaleoni; G Palumbo; D Fanini
[Heterocyclic systems. V. Synthesis and CNS activity of derivatives of 6H-pyrrolo (1,2-a) (1,4)-benzodiazepine].
Il Farmaco; edizione scientifica 1984;39(8):707-17.
1984: Federico Corelli; Silvio Massa; G Stefancich; Marino Artico; S Panico; N Simonetti
Researches on antibacterial and antifungal agents. II - Synthesis of 1-ethyl-1,4-dihydro-4-oxo-7-(1-pyrrolidinyl)quinoline-3-carboxylic acid, a novel highly active, broad-spectrum antibacterial agent related to piromidic acid.
Il Farmaco; edizione scientifica 1984;39(2):95-109.
1983: Silvio Massa; Federico Corelli; Giancarlo Pantaleoni; G Palumbo
[Heterocyclic systems. IV. Synthesis and CNS activity of derivatives of 4H,6H-pyrrolo[1,2-a][4,1]-benzoxazepine].
Il Farmaco; edizione scientifica 1983;38(11):893-903.
1983: Federico Corelli; Silvio Massa; G Stefancich; Marino Artico; S Panico; N Simonetti
Researches on antibacterial and antifungal agents. I. Analogs of nalidixic acid with a pyrrole moiety.
Il Farmaco; edizione scientifica 1983;38(4):219-31.
1981: Silvio Massa; Federico Corelli; G De Martino; Giancarlo Pantaleoni; D Fanini; G Palumbo
[Heterocyclic systems. III. Synthesis and CNS activity of derivatives of pyrrole(2,1-c) (1,4)benzodiazocine].
Il Farmaco; edizione scientifica 1981;36(6):425-31.