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Massimo Masserini

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Chemicals & Drugs

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Alzheimer's Disease

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Francesca Re; Maria Gregori; Massimo Masserini
Nanotechnology for neurodegenerative disorders.
Francesca Re; Maria Gregori; Massimo Masserini
Nanotechnology for neurodegenerative disorders.
Benjamin Le Droumaguet; Noiray Magali; Andrei Maksimenko; Massimo Masserini; Simona Mura; Julien Nicolas; Francesco Nicotra; Elisa Salvati; Wiep Scheper; Cristiano Zona; Cristina Airoldi; Karine Andrieux; Davide Brambilla; Mara Canovi; Line De Kimpe; Orfeu Flores; Marco Gobbi; Barbara La Ferla; Patrick Couvreur
Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease.

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2012: Francesca Re; Maria Gregori; Massimo Masserini
Nanotechnology for neurodegenerative disorders.
Nanomedicine : nanotechnology, biology, and medicine 2012;8 Suppl 1():S51-8.
2012: Francesca Re; Maria Gregori; Massimo Masserini
Nanotechnology for neurodegenerative disorders.
Maturitas 2012;73(1):45-51.
2012: Benjamin Le Droumaguet; Noiray Magali; Andrei Maksimenko; Massimo Masserini; Simona Mura; Julien Nicolas; Francesco Nicotra; Elisa Salvati; Wiep Scheper; Cristiano Zona; Cristina Airoldi; Karine Andrieux; Davide Brambilla; Mara Canovi; Line De Kimpe; Orfeu Flores; Marco Gobbi; Barbara La Ferla; Patrick Couvreur
Versatile and efficient targeting using a single nanoparticulate platform: application to cancer and Alzheimer's disease.
ACS nano 2012;6(7):5866-79.
2012: Alessandra Bulbarelli; Emanuela Cazzaniga; Carlo Ferrarese; Elena Lonati; Massimo Masserini; Antonina Orlando; Fabrizio Piazza; Anna Brambilla; Giulio Sancini
Aβ42 production in brain capillary endothelial cells after oxygen and glucose deprivation.
Molecular and cellular neurosciences 2012;49(4):415-22.
2011: Francesca Re; Roberta Rigolio; Mario Salmona; Alfredo Cagnotto; Ilaria Cambianica; Gianluigi Forloni; Maria Gregori; Barbara La Ferla; Massimo Masserini; Francesco Nicotra; Silvia Sesana; Cristiano Zona; Giulio Sancini
Functionalization of liposomes with ApoE-derived peptides at different density affects cellular uptake and drug transport across a blood-brain barrier model.
Nanomedicine : nanotechnology, biology, and medicine 2011;7(5):551-9.
2011: Emanuela Cazzaniga; Alessandra Bulbarelli; Elena Lonati; Antonina Orlando; Francesca Re; Maria Gregori; Massimo Masserini
Abeta peptide toxicity is reduced after treatments decreasing phosphatidylethanolamine content in differentiated neuroblastoma cells.
Neurochemical research 2011;36(5):863-9.
2011: I Rivolta; A Panariti; B Lettiero; S Sesana; P Gasco; M R Gasco; Massimo Masserini; G Miserocchi
Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticles.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(1):45-53.
2010: Cristina Airoldi; Dario Aurilia; Laura Colombo; Maria Gregori; Massimo Masserini; Massimo Messa; Francesco Nicotra; Mario Salmona; Erika Sironi; Cristiano Zona; Barbara La Ferla
Curcumin derivatives as new ligands of Aβ peptides.
Journal of biotechnology 2010;156(4):317-24.
2010: Francesca Re; Mario Salmona; Elisa Salvati; Alfredo Cagnotto; Ilaria Cambianica; Pierre-Olivier Couraud; Massimo Masserini; S Moein Moghimi; Silvia Sesana; Giulio Sancini
Functionalization with ApoE-derived peptides enhances the interaction with brain capillary endothelial cells of nanoliposomes binding amyloid-beta peptide.
Journal of biotechnology 2010;156(4):341-6.
2010: Maria Gregori; Valeria Cassina; Doriano Brogioli; Domenico Salerno; Line De Kimpe; Wiep Scheper; Massimo Masserini; Francesco Mantegazza
Stability of Aβ (1-42) peptide fibrils as consequence of environmental modifications.
European biophysics journal : EBJ 2010;39(12):1613-23.
2009: Alessandra Bulbarelli; Elena Lonati; Emanuela Cazzaniga; Maria Gregori; Massimo Masserini
Pin1 affects Tau phosphorylation in response to Abeta oligomers.
Molecular and cellular neurosciences 2009;42(1):75-80.
2009: Alessandra Bulbarelli; Elena Lonati; Emanuela Cazzaniga; Francesca Re; Silvia Sesana; Donatella Barisani; Giulio Sancini; Tatsuro Mutoh; Massimo Masserini
TrkA pathway activation induced by amyloid-beta (Abeta).
Molecular and cellular neurosciences 2009;40(3):365-73.
2008: Emanuela Cazzaniga; Alessandra Bulbarelli; Elena Lonati; Francesca Re; Gloria Galimberti; Elena Gatti; Marina Pitto; Carlo Ferrarese; Massimo Masserini
Enhanced folate binding of cultured fibroblasts from Alzheimer's disease patients.
Neuroscience letters 2008;436(3):317-20.
2008: Silvia Sesana; Francesca Re; Alessandra Bulbarelli; Domenico Salerno; Emanuela Cazzaniga; Massimo Masserini
Membrane features and activity of GPI-anchored enzymes: alkaline phosphatase reconstituted in model membranes.
Biochemistry 2008;47(19):5433-40.
2008: Francesca Re; Silvia Sesana; Alberto Barbiroli; Francesco Bonomi; Emanuela Cazzaniga; Elena Lonati; Alessandra Bulbarelli; Massimo Masserini
Prion protein structure is affected by pH-dependent interaction with membranes: a study in a model system.
FEBS letters 2008;582(2):215-20.
2007: Emanuela Cazzaniga; Alessandra Bulbarelli; Arianna Cassetti; Elena Lonati; Francesca Re; Paola Palestini; Tatsuro Mutoh; Massimo Masserini
Beta-amyloid (25-35) enhances lipid metabolism and protein ubiquitination in cultured neurons.
Journal of neuroscience research 2007;85(10):2253-61.
2007: Laura Botto; Massimo Masserini; Paola Palestini
Changes in the composition of detergent-resistant membrane domains of cultured neurons following protein kinase C activation.
Journal of neuroscience research 2007;85(2):443-50.
2005: Massimo Masserini; Marina Pitto; Francesca Raimondo; Emanuela Cazzaniga; Silvia Sesana; Tiziana Bellini
Methyl-beta-cyclodextrin treatment affects the thermotropic behaviour of membranes and detergent-resistant membrane fractions of cultured A431 cells.
Biological & pharmaceutical bulletin 2005;28(12):2185-8.
2005: Paolo Ceppi; Sara Colombo; Maura Francolini; Francesca Raimondo; Nica Borgese; Massimo Masserini
Two tail-anchored protein variants, differing in transmembrane domain length and intracellular sorting, interact differently with lipids.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16269-74.
2005: Francesca Raimondo; Paolo Ceppi; Katia Guidi; Massimo Masserini; Claudia Foletti; Marina Pitto
Proteomics of plasma membrane microdomains.
Expert review of proteomics 2005;2(5):793-807.
2005: Marina Pitto; Francesca Raimondo; Chiara Zoia; Laura Brighina; Carlo Ferrarese; Massimo Masserini
Enhanced GM1 ganglioside catabolism in cultured fibroblasts from Alzheimer patients.
Neurobiology of aging 2005;26(6):833-8.
2004: Vanessa Sangiorgio; Marina Pitto; Paola Palestini; Massimo Masserini
GPI-anchored proteins and lipid rafts.
The Italian journal of biochemistry 2004;53(2):98-111.
2004: Laura Botto; Massimo Masserini; Arianna Cassetti; Paola Palestini
Immunoseparation of Prion protein-enriched domains from other detergent-resistant membrane fractions, isolated from neuronal cells.
FEBS letters 2004;557(1-3):143-7.
2002: Daniela Ravasi; Massimo Masserini; Giuseppe Vecchio; Yu-Teh Li; Su-Chen Li
Study of interaction of GM2 activator protein with GM2 using circular dichroism and fluorescence spectroscopy.
Neurochemical research 2002;27(7-8):785-92.
2002: Marina Pitto; Marco Parenti; Francesca Guzzi; Fulvio Magni; Paola Palestini; Daniela Ravasi; Massimo Masserini
Palmitic is the main fatty acid carried by lipids of detergent-resistant membrane fractions from neural and non-neural cells.
Neurochemical research 2002;27(7-8):729-34.
2002: Daniela Ravasi; Anita Ferraretto; Maria Fausta Omodeo-salè; Guido Tettamanti; Marina Pitto; Massimo Masserini
Ethanol-induced increase of sphingosine recycling for ganglioside biosynthesis: a study performed on cerebellar granule cells in culture.
Journal of neuroscience research 2002;69(1):80-5.
2002: Paola Palestini; Laura Botto; Francesca Guzzi; Chiara Calvi; Daniela Ravasi; Massimo Masserini; Marina Pitto
Developmental changes in the protein composition of sphingolipid- and cholesterol-enriched membrane domains of rat cerebellar granule cells.
Journal of neuroscience research 2002;67(6):729-38.
2002: Massimo Masserini; Paola Palestini; Marina Pitto; Vanna Chigorno; Sandro Sonnino
Preparation and use of liposomes for the study of sphingolipid segregation in membrane model systems.
Methods in molecular biology (Clifton, N.J.) 2002;199():17-27.
2001: Massimo Masserini; Daniela Ravasi
Role of sphingolipids in the biogenesis of membrane domains.
Biochimica et biophysica acta 2001;1532(3):149-61.
2001: Maria C Manfrinato; Tiziana Bellini; Massimo Masserini; Maurizio Tomasi; Franco Dallocchio
Thermal stability of the hemagglutinin-neuraminidase from Sendai virus evidences two folding domains.
FEBS letters 2001;495(1-2):48-51.
2000: M F Omodeo Salè; Angela M Rizzo; Massimo Masserini
Effect of ethanol amine plasmalogens on Fe-induced peroxidation of arachidonic acid in dipalmitoylphosphatidylcholine vesicles.
Biological & pharmaceutical bulletin 2000;23(12):1410-3.
2000: Paola Palestini; Marina Pitto; G Tedeschi; Anita Ferraretto; Marco Parenti; J Brunner; Massimo Masserini
Tubulin anchoring to glycolipid-enriched, detergent-resistant domains of the neuronal plasma membrane.
The Journal of biological chemistry 2000;275(14):9978-85.
2000: Marina Pitto; J Brunner; Anita Ferraretto; Daniela Ravasi; Paola Palestini; Massimo Masserini
Use of a photoactivable GM1 ganglioside analogue to assess lipid distribution in caveolae bilayer.
Glycoconjugate journal 2000;17(3 -4):215-22.
1999: Marina Pitto; Paola Palestini; Anita Ferraretto; Silvio Flati; Antonio Pavan; Daniela Ravasi; Massimo Masserini; G Bottiroli
Dynamics of glycolipid domains in the plasma membrane of living cultured neurons, following protein kinase C activation: a study performed by excimer-formation imaging.
The Biochemical journal 1999;344 Pt 1():177-84.
1999: Paola Palestini; Massimo Masserini; G Bottiroli; J Brunner; Tatsuro Mutoh; Anita Ferraretto; Daniela Ravasi; Marina Pitto
Involvement of glycolipid-enriched domains in the transduction mechanism of neurotrophins in cultured neurons.
Bioscience reports 1999;19(5):385-95.
1999: Mikael Simons; T Friedrichson; J B Schulz; Marina Pitto; Massimo Masserini; Teymuras V Kurzchalia
Exogenous administration of gangliosides displaces GPI-anchored proteins from lipid microdomains in living cells.
Molecular biology of the cell 1999;10(10):3187-96.
1999: Massimo Masserini; Paola Palestini; Marina Pitto
Glycolipid-enriched caveolae and caveolae-like domains in the nervous system.
Journal of neurochemistry 1999;73(1):1-11.
1999: Marina Pitto; Paola Palestini; Anita Ferraretto; Mario Marazzi; V Donati; Leonarda Falcone; Massimo Masserini
Interaction of liposomes composed of phospholipids, GM1 ganglioside and cholesterol with human keratinocytes in culture.
Archives of dermatological research 1999;291(4):232-7.
1998: Marina Pitto; Tatsuro Mutoh; M Kuriyama; Anita Ferraretto; Paola Palestini; Massimo Masserini
Influence of endogenous GM1 ganglioside on TrkB activity, in cultured neurons.
FEBS letters 1998;439(1-2):93-6.
1998: Paola Palestini; Marina Pitto; Anita Ferraretto; Guido Tettamanti; Massimo Masserini
Change of ganglioside accessibility at the plasma membrane surface of cultured neurons, following protein kinase C activation.
Biochemistry 1998;37(9):3143-8.
1998: Massimo Masserini; Marina Pitto; Anita Ferraretto; J Brunne; Paola Palestini
Glycolipid-protein interaction in the mechanism of signal transduction: studies with a photoactivable ganglioside analogue.
Acta biochimica Polonica 1998;45(2):393-401.
1997: Paola Palestini; N Toppi; Anita Ferraretto; Marina Pitto; Massimo Masserini
Ganglioside lateralization in the brain of female rats.
Journal of neuroscience research 1997;50(4):643-8.
1997: Anita Ferraretto; Marina Pitto; Paola Palestini; Massimo Masserini
Lipid domains in the membrane: thermotropic properties of sphingomyelin vesicles containing GM1 ganglioside and cholesterol.
Biochemistry 1997;36(30):9232-6.
1996: Anita Ferraretto; Sandro Sonnino; Marco Soria; Massimo Masserini
Characterization of biotinylated liposomes sensitive to temperature and pH: new tools for anti-cancer drug delivery.
Chemistry and physics of lipids 1996;82(2):133-9.
1996: Marina Pitto; Paola Palestini; Massimo Masserini
Dependence of rat liver CMP-N-acetylneuraminate:GM1 sialyltransferase (SAT IV) activity on the ceramide composition of GM1 ganglioside.
FEBS letters 1996;383(3):223-6.
1995: A M Fra; Massimo Masserini; Paola Palestini; S Sonnino; Kai Simons
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface.
FEBS letters 1995;375(1-2):11-4.
1995: F Omodeo-Salé; Marina Pitto; Massimo Masserini; Paola Palestini
Effects of chronic ethanol exposure on cultured cerebellar granule cells.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1995;26(2):159-69.
1995: Paola Palestini; Marina Pitto; Sandro Sonnino; M F Omodeo-Salè; Massimo Masserini
Spontaneous transfer of GM3 ganglioside between vesicles.
Chemistry and physics of lipids 1995;77(2):253-60.
1994: A Terzaghi; Guido Tettamanti; Paola Palestini; D Acquotti; G Bottiroli; Massimo Masserini
Fluorescence excimer formation imaging: a new technique to investigate association to cells and membrane behavior of glycolipids.
European journal of cell biology 1994;65(1):172-7.
1994: Paola Palestini; Massimo Masserini; Guido Tettamanti
Exposure to galactose oxidase of GM1 ganglioside molecular species embedded into phospholipid vesicles.
FEBS letters 1994;350(2-3):219-22.
1994: G M Cherchi; M Formato; P Demuro; Massimo Masserini; I Varani; G DeLuca
Modifications of low density lipoprotein induced by the interaction with human plasma glycosaminoglycan-protein complexes.
Biochimica et biophysica acta 1994;1212(3):345-52.
1994: Sandro Sonnino; D Acquotti; L Cantu; Vanna Chigorno; MANUELA VALSECCHI; R Casellato; Massimo Masserini; M Corti; Pietro Allevi; Guido Tettamanti
Synthesis and aggregative properties of GM1 ganglioside (IV3Neu5AcGgOse4Cer) containing D-(+)-2-hydroxystearic acid.
Chemistry and physics of lipids 1994;69(2):95-104.
1994: I Varani; A Terzaghi; L Donati; Mario Marazzi; Massimo Masserini; Guido Tettamanti
Protective effect of some exogenous glycolipids on human cultured keratinocytes against lipid peroxidation.
Archives of dermatological research 1994;286(8):481-3.
1993: A Giuliani; Paola Palestini; A D'Aniello; Massimo Masserini
Action of alpha-L-fucoside from Octopus vulgaris hepatopancreas on phospholipid vesicles containing the fucosylated ganglioside FucGM1.
Glycoconjugate journal 1993;10(6):447-52.
1993: H C Loughrey; Anita Ferraretto; A M Cannon; G Acerbis; F Sudati; G Bottiroli; Massimo Masserini; Marco Soria
Characterisation of biotinylated liposomes for in vivo targeting applications.
FEBS letters 1993;332(1-2):183-8.
1993: A Terzaghi; Guido Tettamanti; Massimo Masserini
Interaction of glycosphingolipids and glycoproteins: thermotropic properties of model membranes containing GM1 ganglioside and glycophorin.
Biochemistry 1993;32(37):9722-5.
1993: Paola Palestini; Massimo Masserini; A Fiorilli; E Calappi; Guido Tettamanti
Age-related changes in the ceramide composition of the major gangliosides present in rat brain subcellular fractions enriched in plasma membranes of neuronal and myelin origin.
Journal of neurochemistry 1993;61(3):955-60.
1992: E Calappi; Massimo Masserini; Giampietro Schiavo; Cesare Montecucco; Guido Tettamanti
Lipid interaction of tetanus neurotoxin. A calorimetric and fluorescence spectroscopy study.
FEBS letters 1992;309(2):107-10.
1992: M F Omodeo-Sale; Paola Palestini; Massimo Masserini
Thermotropic behavior of fatty acid ethyl esters in phospholipid liposomes.
Chemistry and physics of lipids 1992;61(2):149-55.
1992: Massimo Masserini; Ernesto Freire; Paola Palestini; E Calappi; Guido Tettamanti
Fuc-GM1 ganglioside mimics the receptor function of GM1 for cholera toxin.
Biochemistry 1992;31(8):2422-6.
1991: Paola Palestini; Massimo Masserini; A Fiorilli; E Calappi; Guido Tettamanti
Evidence for nonrandom distribution of GD1a ganglioside in rabbit brain microsomal membranes.
Journal of neurochemistry 1991;57(3):748-53.
1991: F Omodeo-Salé; C Lindi; Paola Palestini; Massimo Masserini
Role of phosphatidylethanol in membranes. Effects on membrane fluidity, tolerance to ethanol, and activity of membrane-bound enzymes.
Biochemistry 1991;30(9):2477-82.
1990: Massimo Masserini; Paola Palestini; Marina Pitto; Vanna Chigorno; M Tomasi; Guido Tettamanti
Cyclic AMP accumulation in HeLa cells induced by cholera toxin. Involvement of the ceramide moiety of GM1 ganglioside.
The Biochemical journal 1990;271(1):107-11.
1990: Paolo Sarti; Giovanni Antonini; Francesco Malatesta; beatrice vallone; Maurizio Brunori; Massimo Masserini; Paola Palestini; G Tettamanti
Effect of gangliosides on membrane permeability studied by enzymic and fluorescence-spectroscopy techniques.
The Biochemical journal 1990;267(2):413-6.
1990: Massimo Masserini; A Giuliani; Paola Palestini; D Acquotti; Marina Pitto; Vanna Chigorno; Guido Tettamanti
Association to HeLa cells and surface behavior of exogenous gangliosides studied with a fluorescent derivative of GM1.
Biochemistry 1990;29(3):697-701.
1990: Paola Palestini; Massimo Masserini; Sandro Sonnino; Anna Giuliani; Guido Tettamanti
Changes in the ceramide composition of rat forebrain gangliosides with age.
Journal of neurochemistry 1990;54(1):230-5.
1989: Augusto Pessina; E Mineo; Massimo Masserini; Maria Grazia Neri; Clementina E A Cocuzza
Inhibition of murine leukemia (WEHI-3B and L1210) proliferation by cholera toxin B subunit.
Biochimica et biophysica acta 1989;1013(3):206-11.
1989: Massimo Masserini; Paola Palestini; Ernesto Freire
Influence of glycolipid oligosaccharide and long-chain base composition on the thermotropic properties of dipalmitoylphosphatidylcholine large unilamellar vesicles containing gangliosides.
Biochemistry 1989;28(12):5029-34.
1988: Giovanna Cervato; Paola Viani; Massimo Masserini; C Di Iorio; Benvenuto Cestaro
Studies on peroxidation of arachidonic acid in different liposomes below and above phase transition temperature.
Chemistry and physics of lipids 1988;49(1-2):135-9.
1988: Massimo Masserini; Paola Palestini; B Venerando; A Fiorilli; D Acquotti; Guido Tettamanti
Interactions of proteins with ganglioside-enriched microdomains on the membrane: the lateral phase separation of molecular species of GD1a ganglioside, having homogeneous long-chain base composition, is recognized by Vibrio cholerae sialidase.
Biochemistry 1988;27(20):7973-8.
1986: D Acquotti; Sandro Sonnino; Massimo Masserini; L Casella; G Fronza; Guido Tettamanti
A new chemical procedure for the preparation of gangliosides carrying fluorescent or paramagnetic probes on the lipid moiety.
Chemistry and physics of lipids 1986;40(1):71-86.
1985: Massimo Masserini; A Giuliani; B Venerando; A Fiorilli; A D'Aniello; Guido Tettamanti
Alpha-fucosidase-ganglioside interactions. Action of alpha-L-fucosidase from the hepatopancreas of Octopus vulgaris on a fucose-containing ganglioside (Fuc-GM1).
The Biochemical journal 1985;229(3):595-603.
1985: B Venerando; A Fiorilli; Massimo Masserini; A Giuliani; Guido Tettamanti
Interactions of pig brain cytosolic sialidase with gangliosides. Formation of catalytically inactive enzyme-ganglioside complexes.
Biochimica et biophysica acta 1985;833(1):82-92.
1983: S Sonnino; R Ghidoni; Vanna Chigorno; Massimo Masserini; G Tettamanti
Recognition by two-dimensional thin-layer chromatography and densitometric quantification of alkali-labile gangliosides from the brain of different animals.
Analytical biochemistry 1983;128(1):104-14.
1982: Massimo Masserini; S Sonnino; R Ghidoni; Vanna Chigorno; G Tettamanti
Galactose oxidase action on GM1 ganglioside in micellar and vesicular dispersions.
Biochimica et biophysica acta 1982;688(2):333-40.
1981: E Bertoli; Massimo Masserini; S Sonnino; R Ghidoni; Benvenuto Cestaro; G Tettamanti
Electron paramagnetic resonance studies on the fluidity and surface dynamics of egg phosphatidylcholine vesicles containing gangliosides.
Biochimica et biophysica acta 1981;647(2):196-202.
1981: M Corti; V Degriorgio; S Sonnino; R Ghidoni; Massimo Masserini; G Tettamanti
GM1-ganglioside-Triton X-100 mixed micelles: changes of micellar properties studied by laser-light scattering and enzymatic methods.
Chemistry and physics of lipids 1981;28(3):197-214.