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Norma Masson

Research Profile

Chemicals & Drugs

Phenomena

Anatomy

Concepts & Ideas

Protein Structure, Tertiary

Physiology

Gene Expression Regulation

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Publications

TOP 3
Norma Masson; Melroy X Miranda; Lucy J Ambrose; Benedikt M Kessler; Christopher J Schofield; Rok Sekirnik; Rachelle S Singleton; Ya-Min Tian; David C Trudgian; Peter J Ratcliffe
The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity.
Alexandra Grosfeld; Ineke P Stolze; Matthew E Cockman; Christopher W Pugh; Mariola Edelmann; Benedikt Kessler; Alex N Bullock; Peter J Ratcliffe; Norma Masson
Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.
Matthew E Cockman; David E Lancaster; Ineke P Stolze; Kirsty S Hewitson; Michael McDonough; Mathew L Coleman; Charlotte H Coles; Xiaohong Yu; Ron Thomas Hay; Steven C Ley; Christopher W Pugh; Neil J Oldham; Norma Masson; Christopher J Schofield; Peter J Ratcliffe
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).

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All Publications

2012: Norma Masson; Melroy X Miranda; Lucy J Ambrose; Benedikt M Kessler; Christopher J Schofield; Rok Sekirnik; Rachelle S Singleton; Ya-Min Tian; David C Trudgian; Peter J Ratcliffe
The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity.
EMBO reports 2012;13(3):251-7.
2007: Alexandra Grosfeld; Ineke P Stolze; Matthew E Cockman; Christopher W Pugh; Mariola Edelmann; Benedikt Kessler; Alex N Bullock; Peter J Ratcliffe; Norma Masson
Interaction of hydroxylated collagen IV with the von hippel-lindau tumor suppressor.
The Journal of biological chemistry 2007;282(18):13264-9.
2006: Matthew E Cockman; David E Lancaster; Ineke P Stolze; Kirsty S Hewitson; Michael McDonough; Mathew L Coleman; Charlotte H Coles; Xiaohong Yu; Ron Thomas Hay; Steven C Ley; Christopher W Pugh; Neil J Oldham; Norma Masson; Christopher J Schofield; Peter J Ratcliffe
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH).
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14767-72.
2004: Norma Masson; Rebecca J Appelhoff; Jason R Tuckerman; Ya-Min Tian; Hans Demol; Magda Puype; Joël Vandekerckhove; Peter J Ratcliffe; Christopher W Pugh
The HIF prolyl hydroxylase PHD3 is a potential substrate of the TRiC chaperonin.
FEBS letters 2004;570(1-3):166-70.
2004: Norma Masson; Peter J Ratcliffe
Analysis of von Hippel-Lindau tumor suppressor as a mediator of cellular oxygen sensing.
Methods in enzymology 2004;381():305-20.
2003: Norma Masson; Peter J Ratcliffe
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels.
Journal of cell science 2003;116(Pt 15):3041-9.
2002: Carsten Willam; Norma Masson; Ya-Min Tian; S Aleema Mahmood; Michael I Wilson; Roy Bicknell; Kai-Uwe Eckardt; Patrick H Maxwell; Peter J Ratcliffe; Christopher W Pugh
Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10423-8.
2001: Andrew C R Epstein; Jonathan Gleadle; Luke A McNeill; Kirsty S Hewitson; JF O'Rourke; David R Mole; Mridul Mukherji; Eric Metzen; Michael I Wilson; A Dhanda; Ya-Min Tian; Norma Masson; D L Hamilton; Panu M Jaakkola; R Barstead; Jonathan Hodgkin; Patrick H Maxwell; Christopher W Pugh; Christopher J Schofield; Peter J Ratcliffe
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Cell 2001;107(1):43-54.
2001: Norma Masson; Carsten Willam; Patrick H Maxwell; Christopher W Pugh; Peter J Ratcliffe
Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation.
The EMBO journal 2001;20(18):5197-206.
2000: Matthew E Cockman; Norma Masson; David R Mole; Panu M Jaakkola; GW Chang; Steven C Clifford; Eamonn R Maher; Christopher W Pugh; Peter J Ratcliffe; Patrick H Maxwell
Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
The Journal of biological chemistry 2000;275(33):25733-41.