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Patrick Masson

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Wei Jiang; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond.
Eugénie Carletti; Jacques-Philippe Colletier; Oksana Lockridge; Patrick Masson; Florian Nachon; Gianluca Santoni; Lawrence M Schopfer; Martin Weik
Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry.
Ellen G Duysen; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.

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2013: Wei Jiang; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Mass spectrometry method to identify aging pathways of Sp- and Rp-tabun adducts on human butyrylcholinesterase based on the acid labile P-N bond.
Toxicological sciences : an official journal of the Society of Toxicology 2013;132(2):390-8.
2013: Eugénie Carletti; Jacques-Philippe Colletier; Oksana Lockridge; Patrick Masson; Florian Nachon; Gianluca Santoni; Lawrence M Schopfer; Martin Weik
Inhibition pathways of the potent organophosphate CBDP with cholinesterases revealed by X-ray crystallographic snapshots and mass spectrometry.
Chemical research in toxicology 2013;26(2):280-9.
2012: Ellen G Duysen; Patrick Masson; Florian Nachon; Lawrence M Schopfer; John R Cashman; Oksana Lockridge
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.
Chemico-biological interactions 2012;195(3):189-98.
2011: Mariya Liyasova; Clement E Furlong; Bin Li; Patrick Masson; Florian Nachon; Lawrence M Schopfer; Oksana Lockridge
Exposure to tri-o-cresyl phosphate detected in jet airplane passengers.
Toxicology and applied pharmacology 2011;256(3):337-47.
2011: Marie Trovaslet-Leroy; Laurent Verdier; Ladislav Novotny; Frédérique Renault; Daniel Rochu; Xavier Brazzolotto; Marie-Thérèse Froment; Emilie Gillon; Daniel Jun; Mélanie Loiodice; Patrick Masson; Jan Misik; Lucie Musilova; Florian Nachon
Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents.
Toxicology letters 2011;206(1):14-23.
2011: Patrick Masson
Evolution of and perspectives on therapeutic approaches to nerve agent poisoning.
Toxicology letters 2011;206(1):5-13.
2011: Thomas Cherrier; Mikael Elias; Guillaume Gotthard; Houda Hallay; Andrea Janossy; Alicia Jeudy; Valentin Le Douce; Patrick Masson; Olivier Rohr; Ermanno Candolfi; Eric Chabrière; C Schwartz
Human-Phosphate-Binding-Protein inhibits HIV-1 gene transcription and replication.
Virology journal 2011;8():352.
2010: Jose R Tormos; Kenneth L Wiley; Yi Wang; Didier Fournier; Patrick Masson; Florian Nachon; Daniel M Quinn
Accumulation of tetrahedral intermediates in cholinesterase catalysis: a secondary isotope effect study.
Journal of the American Chemical Society 2010;132(50):17751-9.
2010: Florian Nachon; Eugenie Carletti; Worek Franz; Patrick Masson
Aging mechanism of butyrylcholinesterase inhibited by an N-methyl analogue of tabun: implications of the trigonal-bipyramidal transition state rearrangement for the phosphylation or reactivation of cholinesterases.
Chemico-biological interactions 2010;187(1-3):44-8.
2010: Patrick Masson; Florian Nachon; Oksana Lockridge
Structural approach to the aging of phosphylated cholinesterases.
Chemico-biological interactions 2010;187(1-3):157-62.
2010: Marie Trovaslet-Leroy; Claude Jolivalt; Marie-Thérèse Froment; Bernardin Brasme; Bertrand Lefebvre; Denis Daveloose; Florian Nachon; Patrick Masson
Application of laccase-mediator system (LMS) for the degradation of organophosphorus compounds.
Chemico-biological interactions 2010;187(1-3):393-6.
2010: Bin Li; Ivan Ricordel; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Patrick Masson; Oksana Lockridge
Dichlorvos, chlorpyrifos oxon and Aldicarb adducts of butyrylcholinesterase, detected by mass spectrometry in human plasma following deliberate overdose.
Journal of applied toxicology : JAT 2010;30(6):559-65.
2010: Bin Li; Ivan Ricordel; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Florian Nachon; Patrick Masson; Oksana Lockridge
Detection of adduct on tyrosine 411 of albumin in humans poisoned by dichlorvos.
Toxicological sciences : an official journal of the Society of Toxicology 2010;116(1):23-31.
2010: Eugénie Carletti; Jacques-Philippe Colletier; Florine Dupeux; Marie Trovaslet; Patrick Masson; Florian Nachon
Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation.
Journal of medicinal chemistry 2010;53(10):4002-8.
2010: Frédérique Renault; Tiffany Carus; Cécile Cléry-Barraud; Mikael Elias; Eric Chabrière; Patrick Masson; Daniel Rochu
Integrative analytical approach by capillary electrophoresis and kinetics under high pressure optimized for deciphering intrinsic and extrinsic cofactors that modulate activity and stability of human paraoxonase (PON1).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(17-18):1346-55.
2010: Lawrence M Schopfer; Hasmik Grigoryan; Bin Li; Florian Nachon; Patrick Masson; Oksana Lockridge
Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(17-18):1297-311.
2010: Patrick Masson; Oksana Lockridge
Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior.
Archives of biochemistry and biophysics 2010;494(2):107-20.
2009: Benoît Sanson; Florian Nachon; Jacques-Philippe Colletier; Marie-Thérèse Froment; Lilly Toker; Harry M Greenblatt; Joel Sussman; Yaacov Ashani; Patrick Masson; Israel Silman; Martin Weik
Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime.
Journal of medicinal chemistry 2009;52(23):7593-603.
2009: Eugénie Carletti; Lilian Jacquamet; Mélanie Loiodice; Daniel Rochu; Patrick Masson; Florian Nachon
Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase.
Journal of enzyme inhibition and medicinal chemistry 2009;24(4):1045-55.
2009: Eugénie Carletti; Nadine Aurbek; Emilie Gillon; Mélanie Loiodice; Yvain Nicolet; Juan C Fontecilla-Camps; Patrick Masson; Horst Thiermann; Florian Nachon; Worek Franz
Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun.
The Biochemical journal 2009;421(1):97-106.
2009: Pompea Del Vecchio; Mikael Elias; Luigia Merone; Giuseppe Graziano; Jérôme Dupuy; Luigi Mandrich; Paola Carullo; Bertrand Fournier; Daniel Rochu; Mosè Rossi; Patrick Masson; Eric Chabriere; Giuseppe Manco
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus.
Extremophiles : life under extreme conditions 2009;13(3):461-70.
2009: Patrick Masson; Daniel Rochu
Catalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings.
Acta naturae 2009;1(1):68-79.
2009: Cécile Cléry-Barraud; Frédérique Renault; Julien Leva; Nacéra El Bakdouri; Patrick Masson; Daniel Rochu
Exploring the structural and functional stabilities of different paraoxonase-1 formulations through electrophoretic mobilities and enzyme activity parameters under hydrostatic pressure.
Biochimica et biophysica acta 2009;1794(4):680-8.
2009: He Li; Ivan Ricordel; Larry Tong; Lawrence M Schopfer; Frédéric Baud; Bruno Mégarbane; Eric Maury; Patrick Masson; Oksana Lockridge
Carbofuran poisoning detected by mass spectrometry of butyrylcholinesterase adduct in human serum.
Journal of applied toxicology : JAT 2009;29(2):149-55.
2009: Frank Gabel; Patrick Masson; M-T Froment; B P Doctor; A Saxena; Israel Silman; Giuseppe Zaccai; Martin Weik
Direct correlation between molecular dynamics and enzymatic stability: a comparative neutron scattering study of native human butyrylcholinesterase and its "aged" soman conjugate.
Biophysical journal 2009;96(4):1489-94.
2009: Patrick Masson; Eugénie Carletti; Florian Nachon
Structure, activities and biomedical applications of human butyrylcholinesterase.
Protein and peptide letters 2009;16(10):1215-24.
2008: Eugénie Carletti; He Li; Bin Li; Fredrik Ekström; Yvain Nicolet; Mélanie Loiodice; Emilie Gillon; Marie-Thérèse Froment; Oksana Lockridge; Lawrence M Schopfer; Patrick Masson; Florian Nachon
Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation.
Journal of the American Chemical Society 2008;130(47):16011-20.
2008: He Li; Larry Tong; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Fast affinity purification coupled with mass spectrometry for identifying organophosphate labeled plasma butyrylcholinesterase.
Chemico-biological interactions 2008;175(1-3):68-72.
2008: Hasmik Grigoryan; Lawrence M Schopfer; Charles M Thompson; Alvin V Terry; Patrick Masson; Oksana Lockridge
Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.
Chemico-biological interactions 2008;175(1-3):180-6.
2008: Shi-Jian Ding; John Carr; James E Carlson; Larry Tong; Weihua Xue; Yifeng Li; Lawrence M Schopfer; Bin Li; Florian Nachon; Oluwatoyin Asojo; Charles M Thompson; Steven H Hinrichs; Patrick Masson; Oksana Lockridge
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
Chemical research in toxicology 2008;21(9):1787-94.
2008: Frédéric Dorandeu; A Foquin; R Briot; C Delacour; J Denis; A Alonso; Marie-Thérèse Froment; Frédérique Renault; Guy Lallement; Patrick Masson
An unexpected plasma cholinesterase activity rebound after challenge with a high dose of the nerve agent VX.
Toxicology 2008;248(2-3):151-7.
2008: Mikael Elias; Jerome Dupuy; Luigia Merone; Luigi Mandrich; ELENA PORZIO; Sébastien Moniot; Daniel Rochu; Claude Lecomte; Mosè Rossi; Patrick Masson; Giuseppe Manco; Eric Chabriere
Structural basis for natural lactonase and promiscuous phosphotriesterase activities.
Journal of molecular biology 2008;379(5):1017-28.
2008: Patrick Masson; Marie-Thérèse Froment; Emilie Gillon; Florian Nachon; Oksana Lockridge; Lawrence M Schopfer
Kinetic analysis of effector modulation of butyrylcholinesterase-catalysed hydrolysis of acetanilides and homologous esters.
The FEBS journal 2008;275(10):2617-31.
2008: He Li; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Lamellipodin proline rich peptides associated with native plasma butyrylcholinesterase tetramers.
The Biochemical journal 2008;411(2):425-32.
2008: Firmin Moingeon; Jérôme Roeser; Patrick Masson; Françoise Arnaud; Stéphane Méry
Versatile and efficient functionalisation of multiallylic dendronised polymers: can dense packing be reached?
Chemical communications (Cambridge, England) 2008;(11):1341-3.
2008: Bin Li; Florian Nachon; Marie-Thérèse Froment; Laurent Verdier; Jean-Claude Debouzy; Bernardo Brasme; Emilie Gillon; Lawrence M Schopfer; Oksana Lockridge; Patrick Masson
Binding and hydrolysis of soman by human serum albumin.
Chemical research in toxicology 2008;21(2):421-31.
2007: Daniel Rochu; Eric Chabrière; Frédérique Renault; M Elias; Cécile Cléry-Barraud; Patrick Masson
Stabilization of the active form(s) of human paraoxonase by human phosphate-binding protein.
Biochemical Society transactions 2007;35(Pt 6):1616-20.
2007: Jacques-Philippe Colletier; Antoine Royant; Alexandre Specht; Benoît Sanson; Florian Nachon; Patrick Masson; Giuseppe Zaccai; Joel Sussman; Maurice Goeldner; Israel Silman; Dominique Bourgeois; Martin Weik
Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 11):1115-28.
2007: He Li; Lawrence M Schopfer; Florian Nachon; Marie-Thérèse Froment; Patrick Masson; Oksana Lockridge
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
Toxicological sciences : an official journal of the Society of Toxicology 2007;100(1):136-45.
2007: Patrick Masson; Marie-Thérèse Froment; Emilie Gillon; Florian Nachon; Sultan Darvesh; Lawrence M Schopfer
Kinetic analysis of butyrylcholinesterase-catalyzed hydrolysis of acetanilides.
Biochimica et biophysica acta 2007;1774(9):1139-47.
2007: Patrick Masson; Marie-Thérèse Froment; Sultan Darvesh; Lawrence M Schopfer; Oksana Lockridge
Aryl acylamidase activity of human serum albumin with o-nitrotrifluoroacetanilide as the substrate.
Journal of enzyme inhibition and medicinal chemistry 2007;22(4):463-9.
2007: Mikael Elias; Jerome Dupuy; Luigia Merone; Claude Lecomte; Mosè Rossi; Patrick Masson; Giuseppe Manco; Eric Chabriere
Crystallization and preliminary X-ray diffraction analysis of the hyperthermophilic Sulfolobus solfataricus phosphotriesterase.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 7):553-5.
2007: Daniel Rochu; Frédérique Renault; Cécile Cléry-Barraud; Eric Chabrière; Patrick Masson
Stability of highly purified human paraoxonase (PON1): association with human phosphate binding protein (HPBP) is essential for preserving its active conformation(s).
Biochimica et biophysica acta 2007;1774(7):874-83.
2007: Daniel Rochu; Eric Chabrière; Patrick Masson
Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning.
Toxicology 2007;233(1-3):47-59.
2007: Thomas Poyot; Florian Nachon; Daniel Rochu; D Fournier; Patrick Masson
[Enzyme optimization, mutagenesis and directed evolution].
Annales pharmaceutiques françaises 2007;65(2):119-25.
2007: Renaud Morales; Anne Berna; Philippe Carpentier; Carlos A Contreras-Martel; Frédérique Renault; M Nicodeme; Marie-Laure Chesne-seck; François Bernier; Jerome Dupuy; Christine Schaeffer; Hélène Diemer; Alain Van Dorsselaer; Juan C Fontecilla-Camps; Patrick Masson; Daniel Rochu; Eric Chabrière
[Discovery and crystallographic structure of human apolipoprotein].
Annales pharmaceutiques françaises 2007;65(2):98-107.
2007: Patrick Masson
[Presentation. Enzymes: the long pathway from genes to drugs].
Annales pharmaceutiques françaises 2007;65(2):95-7.
2007: Bin Li; Lawrence M Schopfer; Steven H Hinrichs; Patrick Masson; Oksana Lockridge
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411.
Analytical biochemistry 2007;361(2):263-72.
2007: Patrick Masson; Florian Nachon; Daniel Rochu
[Engineering of catalytic bioscavengers of organophosphorus compounds].
Bulletin de l'Académie nationale de médecine 2007;191(1):95-111; discussion 112.
2007: Patrick Masson; Marie-Thérèse Froment; Emilie Gillon; Florian Nachon; Oksana Lockridge; Lawrence M Schopfer
Hydrolysis of oxo- and thio-esters by human butyrylcholinesterase.
Biochimica et biophysica acta 2007;1774(1):16-34.
2006: Thomas Poyot; Florian Nachon; Marie-Thérèse Froment; Mélanie Loiodice; Stacy Wieseler; Lawrence M Schopfer; Oksana Lockridge; Patrick Masson
Mutant of Bungarus fasciatus acetylcholinesterase with low affinity and low hydrolase activity toward organophosphorus esters.
Biochimica et biophysica acta 2006;1764(9):1470-8.
2006: Nicolas Masurier; François Estour; Bertrand Lefèvre; Bernard Brasme; Patrick Masson; Olivier Lafont
Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis.
Carbohydrate research 2006;341(7):935-40.
2006: Frédérique Renault; Eric Chabrière; Jean-Pierre Andrieu; Bernard Dublet; Patrick Masson; Daniel Rochu
Tandem purification of two HDL-associated partner proteins in human plasma, paraoxonase (PON1) and phosphate binding protein (HPBP) using hydroxyapatite chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;836(1-2):15-21.
2006: Renaud Morales; Anne Berna; Philippe Carpentier; Carlos A Contreras-Martel; Frédérique Renault; Murielle Nicodeme; Marie-Laure Chesne-seck; François Bernier; Jerome Dupuy; Christine Schaeffer; Hélène Diemer; Alain Van Dorsselaer; Juan C Fontecilla-Camps; Patrick Masson; Daniel Rochu; Eric Chabriere
Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein.
Structure (London, England : 1993) 2006;14(3):601-9.
2006: Anna Hrabovská; Jean-Claude Debouzy; Marie-Thérèse Froment; Ferdinand Devínsky; Ingrid Pauliková; Patrick Masson
Rat butyrylcholinesterase-catalysed hydrolysis of N-alkyl homologues of benzoylcholine.
The FEBS journal 2006;273(6):1185-97.
2006: Daniel Rochu; Cécile Cléry-Barraud; Frédérique Renault; Aurélie Chevalier; Cassian Bon; Patrick Masson
Capillary electrophoresis versus differential scanning calorimetry for the analysis of free enzyme versus enzyme-ligand complexes: in the search of the ligand-free status of cholinesterases.
Electrophoresis 2006;27(2):442-51.
2006: Carlos A Contreras-Martel; Philippe Carpentier; Renaud Morales; Frédérique Renault; Marie-Laure Chesne-seck; Daniel Rochu; Patrick Masson; Juan C Fontecilla-Camps; Eric Chabrière
Crystallization and preliminary X-ray diffraction analysis of human phosphate-binding protein.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 1):67-9.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Structural data on the aging of diethylphosphoryl-butyrylcholinesterase.
Chemico-biological interactions 2005;157-158():408-9.
2005: Patrick Masson; Lawrence M Schopfer; Marie-Thérèse Froment; Jean-Claude Debouzy; Florian Nachon; Emilie Gillon; Oksana Lockridge; Anna Hrabovska; Boris N Goldstein
Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics.
Chemico-biological interactions 2005;157-158():143-52.
2005: Bin Li; Meghan Sedlacek; Indumathi Manoharan; Rathnam Boopathy; Ellen G Duysen; Patrick Masson; Oksana Lockridge
Butyrylcholinesterase, paraoxonase, and albumin esterase, but not carboxylesterase, are present in human plasma.
Biochemical pharmacology 2005;70(11):1673-84.
2005: Frank Gabel; Martin Weik; Patrick Masson; F Renault; Didier Fournier; L Brochier; B P Doctor; A Saxena; Israel Silman; Giuseppe Zaccai
Effects of soman inhibition and of structural differences on cholinesterase molecular dynamics: a neutron scattering study.
Biophysical journal 2005;89(5):3303-11.
2005: Jose R Tormos; Kenneth L Wiley; Javier Seravalli; Florian Nachon; Patrick Masson; Yvain Nicolet; Daniel M Quinn
The reactant state for substrate-activated turnover of acetylthiocholine by butyrylcholinesterase is a tetrahedral intermediate.
Journal of the American Chemical Society 2005;127(42):14538-9.
2005: Patrick Masson; Claude Balny
Linear and non-linear pressure dependence of enzyme catalytic parameters.
Biochimica et biophysica acta 2005;1724(3):440-50.
2005: Nicolas Masurier; François Estour; Marie-Thérèse Froment; Bertrand Lefèvre; Jean-Claude Debouzy; Bernard Brasme; Patrick Masson; Olivier Lafont
Synthesis of 2-substituted beta-cyclodextrin derivatives with a hydrolytic activity against the organophosphorylester paraoxon.
European journal of medicinal chemistry 2005;40(7):615-23.
2005: Fabrice Mathevet; Patrick Masson; Jean-François Nicoud; Antoine Skoulios
Smectic liquid crystals from supramolecular guanidinium alkanesulfonates.
Journal of the American Chemical Society 2005;127(25):9053-61.
2005: Florian Nachon; Yvain Nicolet; Patrick Masson
[Butyrylcholinesterase: 3D structure, catalytic mechanisms].
Annales pharmaceutiques françaises 2005;63(3):194-206.
2005: Florian Nachon; Oluwatoyin A Asojo; Gloria E. Borgstahl; Patrick Masson; Oksana Lockridge
Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Biochemistry 2005;44(4):1154-62.
2004: Manuel Gutierrez-Nava; Gianluca Accorsi; Patrick Masson; Nicola Armaroli; Jean-François Nierengarten
Polarity effects on the photophysics of dendrimers with an oligophenylenevinylene core and peripheral fullerene units.
Chemistry (Weinheim an der Bergstrasse, Germany) 2004;10(20):5076-86.
2004: Daniel Rochu; Nathalie Viguié; Frédérique Renault; David Crouzier; Marie-Thérèse Froment; Patrick Masson
Contribution of the active-site metal cation to the catalytic activity and to the conformational stability of phosphotriesterase: temperature- and pH-dependence.
The Biochemical journal 2004;380(Pt 3):627-33.
2004: Yuxia Wang; Lawrence M Schopfer; Ellen G Duysen; Florian Nachon; Patrick Masson; Oksana Lockridge
Screening assays for cholinesterases resistant to inhibition by organophosphorus toxicants.
Analytical biochemistry 2004;329(1):131-8.
2004: Patrick Masson; Nicole Bec; Marie-Thérèse Froment; Florian Nachon; Claude Balny; Oksana Lockridge; Lawrence M Schopfer
Rate-determining step of butyrylcholinesterase-catalyzed hydrolysis of benzoylcholine and benzoylthiocholine. Volumetric study of wild-type and D70G mutant behavior.
European journal of biochemistry / FEBS 2004;271(10):1980-90.
2004: Frank Gabel; Martin Weik; B P Doctor; A Saxena; Didier Fournier; L Brochier; F Renault; Patrick Masson; Israel Silman; Giuseppe Zaccai
The influence of solvent composition on global dynamics of human butyrylcholinesterase powders: a neutron-scattering study.
Biophysical journal 2004;86(5):3152-65.
2004: Cécile Cléry-Barraud; Agnès Gaubert; Patrick Masson; Dominique Vidal
Combined effects of high hydrostatic pressure and temperature for inactivation of Bacillus anthracis spores.
Applied and environmental microbiology 2004;70(1):635-7.
2004: Patrick Masson; Boris N Goldstein; Jean-Claude Debouzy; Marie-Thérèse Froment; Oksana Lockridge; Lawrence M Schopfer
Damped oscillatory hysteretic behaviour of butyrylcholinesterase with benzoylcholine as substrate.
European journal of biochemistry / FEBS 2004;271(1):220-34.
2003: Yvain Nicolet; Oksana Lockridge; Patrick Masson; Juan C Fontecilla-Camps; Florian Nachon
Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products.
The Journal of biological chemistry 2003;278(42):41141-7.
2003: Sandra Loudwig; Yvain Nicolet; Patrick Masson; Juan C Fontecilla-Camps; Suzanne Bon; Florian Nachon; Maurice Goeldner
Photoreversible inhibition of cholinesterases: catalytic serine-labeled caged butyrylcholinesterase.
Chembiochem : a European journal of chemical biology 2003;4(8):762-7.
2003: Daniel Rochu; Patrick Masson
[Capillary electrophoresis for monitoring stability of pharmaceutical proteins].
Annales pharmaceutiques françaises 2003;61(3):185-95.
2003: Patrick Masson; Florian Nachon; Cynthia F Bartels; Marie-Thérèse Froment; Fabien Ribes; Cedric Matthews; Oksana Lockridge
High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine.
European journal of biochemistry / FEBS 2003;270(2):315-24.
2002: Denis Josse; Christine Ebel; David Stroebel; Alice Fontaine; frederic borges; Aude Echalier; Delphine Baud; Frédérique Renault; Marc le Maire; Eric Chabrieres; Patrick Masson
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1).
The Journal of biological chemistry 2002;277(36):33386-97.
2002: Cécile Cléry-Barraud; Arie Ordentlich; Haim Grosfeld; Avigdor Shafferman; Patrick Masson
Pressure and heat inactivation of recombinant human acetylcholinesterase. Importance of residue E202 for enzyme stability.
European journal of biochemistry / FEBS 2002;269(17):4297-307.
2002: Patrick Masson; Marie-Thérèse Froment; Sébastien Fort; Fabien Ribes; Nicole Bec; Claude Balny; Lawrence M Schopfer
Butyrylcholinesterase-catalyzed hydrolysis of N-methylindoxyl acetate: analysis of volume changes upon reaction and hysteretic behavior.
Biochimica et biophysica acta 2002;1597(2):229-43.
2002: Fabrice Mathevet; Patrick Masson; Jean-François Nicoud; Antoine Skoulios
Smectic liquid crystals from supramolecular guanidinium alkylbenzenesulfonates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(10):2248-54.
2002: Daniel Rochu; Frédérique Renault; Patrick Masson
Detection of unwanted protein-bound ligands by capillary zone electrophoresis: the case of hidden ligands that stabilize cholinesterase conformation.
Electrophoresis 2002;23(6):930-7.
2002: Patrick Masson; Lawrence M Schopfer; Cynthia F Bartels; Marie-Thérèse Froment; Fabien Ribes; Florian Nachon; Oksana Lockridge
Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite.
Biochimica et biophysica acta 2002;1594(2):313-24.
2002: Daniel Rochu; Nadège Beaufet; Frédérique Renault; Nathalie Viguié; Patrick Masson
The wild type bacterial Co(2+)/Co(2+)-phosphotriesterase shows a middle-range thermostability.
Biochimica et biophysica acta 2002;1594(2):207-18.
2002: Jure Stojan; Marko Golicnik; Marie-Thérèse Froment; Francois Estour; Patrick Masson
Concentration-dependent reversible activation-inhibition of human butyrylcholinesterase by tetraethylammonium ion.
European journal of biochemistry / FEBS 2002;269(4):1154-61.
2002: H Delacour; C Cléry; Patrick Masson; Dominique R Vidal
[Inactivation of bacterial spores by high hydrostatic pressure].
Annales pharmaceutiques françaises 2002;60(1):38-43.
2002: Florian Nachon; Yvain Nicolet; Nathalie Viguié; Patrick Masson; Juan C Fontecilla-Camps; Oksana Lockridge
Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization.
European journal of biochemistry / FEBS 2002;269(2):630-7.
2002: Daniel Rochu; Patrick Masson
Multiple advantages of capillary zone electrophoresis for exploring protein conformational stability.
Electrophoresis 2002;23(2):189-202.
2001: Denis Josse; Oksana Lockridge; W Xie; Cynthia F Bartels; Lawrence M Schopfer; Patrick Masson
The active site of human paraoxonase (PON1).
Journal of applied toxicology : JAT 2001;21 Suppl 1():S7-11.
2001: A Weingand-Ziade; Fabien Ribes; Frédérique Renault; Patrick Masson
Pressure- and heat-induced inactivation of butyrylcholinesterase: evidence for multiple intermediates and the remnant inactivation process.
The Biochemical journal 2001;356(Pt 2):487-93.
2001: Denis Josse; Patrick Masson
[Human plasma paraoxonase (HuPON1): an anti-atherogenic enzyme with organophosphate hydrolase activity].
Annales pharmaceutiques françaises 2001;59(2):108-18.
2001: Daniel Rochu; T Pernet; Frédérique Renault; Cassian Bon; Patrick Masson
Dual effect of high electric field in capillary electrophoresis study of the conformational stability of Bungarus fasciatus acetylcholinesterase.
Journal of chromatography. A 2001;910(2):347-57.
2001: Daniel Rochu; C Georges; J Répiton; Nathalie Viguié; B Saliou; Cassian Bon; Patrick Masson
Thermal stability of acetylcholinesterase from Bungarus fasciatus venom as investigated by capillary electrophoresis.
Biochimica et biophysica acta 2001;1545(1-2):216-26.
2001: Patrick Masson; W Xie; Marie-Thérèse Froment; Oksana Lockridge
Effects of mutations of active site residues and amino acids interacting with the Omega loop on substrate activation of butyrylcholinesterase.
Biochimica et biophysica acta 2001;1544(1-2):166-76.
2000: Oksana Lockridge; Patrick Masson
Pesticides and susceptible populations: people with butyrylcholinesterase genetic variants may be at risk.
Neurotoxicology 2000;21(1-2):113-26.
1999: Patrick Masson; C Cléry; P Guerra; A Redslob; C Albaret; PL Fortier
Hydration change during the aging of phosphorylated human butyrylcholinesterase: importance of residues aspartate-70 and glutamate-197 in the water network as probed by hydrostatic and osmotic pressures.
The Biochemical journal 1999;343 Pt 2():361-9.
1999: F Pilotaz; Patrick Masson
[Huperzine a: an acetylcholinesterase inhibitor with high pharmacological potential].
Annales pharmaceutiques françaises 1999;57(5):363-73.
1999: A Weingand-Ziadé; Frédérique Renault; Patrick Masson
Differential effect of pressure and temperature on the catalytic behaviour of wild-type human butyrylcholinesterase and its D70G mutant.
European journal of biochemistry / FEBS 1999;264(2):327-35.
1999: Patrick Masson; W Xie; Marie-Thérèse Froment; V Levitsky; PL Fortier; C Albaret; Oksana Lockridge
Interaction between the peripheral site residues of human butyrylcholinesterase, D70 and Y332, in binding and hydrolysis of substrates.
Biochimica et biophysica acta 1999;1433(1-2):281-93.
1999: Daniel Rochu; G Ducret; F Ribes; S Vanin; Patrick Masson
Capillary zone electrophoresis with optimized temperature control for studying thermal denaturation of proteins at various pH.
Electrophoresis 1999;20(7):1586-94.
1999: Denis Josse; W Xie; Patrick Masson; Lawrence M Schopfer; Oksana Lockridge
Tryptophan residue(s) as major components of the human serum paraoxonase active site.
Chemico-biological interactions 1999;119-120():79-84.
1999: Denis Josse; W Xie; Patrick Masson; Oksana Lockridge
Human serum paraoxonase (PON1): identification of essential amino acid residues by group-selective labelling and site-directed mutagenesis.
Chemico-biological interactions 1999;119-120():71-8.
1999: Patrick Masson; PL Fortier; C Albaret; C Cléry; P Guerra; Oksana Lockridge
Structural and hydration changes in the active site gorge of phosporhylated butyrylcholinesterase accompanying the aging process.
Chemico-biological interactions 1999;119-120():17-27.
1999: Daniel Rochu; G Ducret; Patrick Masson
Measuring conformational stability of proteins using an optimized temperature-controlled capillary electrophoresis approach.
Journal of chromatography. A 1999;838(1-2):157-65.
1999: Denis Josse; W Xie; Frédérique Renault; Daniel Rochu; Lawrence M Schopfer; Patrick Masson; Oksana Lockridge
Identification of residues essential for human paraoxonase (PON1) arylesterase/organophosphatase activities.
Biochemistry 1999;38(9):2816-25.
1999: V Levitsky; W Xie; Marie-Thérèse Froment; Oksana Lockridge; Patrick Masson
Polyol-induced activation by excess substrate of the D70G butyrylcholinesterase mutant.
Biochimica et biophysica acta 1999;1429(2):422-30.
1999: Patrick Masson
[Action of hydrostatic pressure on proteins: emergence of high pressure biotechnology, potential pharmaceutical and medical applications].
Annales pharmaceutiques françaises 1999;57(1):49-55.
1998: Patrick Masson; Denis Josse; Oksana Lockridge; N Viguié; C Taupin; Cyril Buhler
Enzymes hydrolyzing organophosphates as potential catalytic scavengers against organophosphate poisoning.
Journal of physiology, Paris 1998;92(5-6):357-62.
1998: Marie-Thérèse Froment; Oksana Lockridge; Patrick Masson
Resistance of butyrylcholinesterase to inactivation by ultrasound: effects of ultrasound on catalytic activity and subunit association.
Biochimica et biophysica acta 1998;1387(1-2):53-64.
1998: Patrick Masson; Marie-Thérèse Froment; PL Fortier; J E Visicchio; Cynthia F Bartels; Oksana Lockridge
Butyrylcholinesterase-catalysed hydrolysis of aspirin, a negatively charged ester, and aspirin-related neutral esters.
Biochimica et biophysica acta 1998;1387(1-2):41-52.
1998: Daniel Rochu; C Rothlisberger; C Taupin; Frédérique Renault; J Gagnon; Patrick Masson
Purification, molecular characterization and catalytic properties of a Pseudomonas fluorescens enzyme having cholinesterase-like activity.
Biochimica et biophysica acta 1998;1385(1):126-38.
1997: Patrick Masson; PL Fortier; C Albaret; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Aging of di-isopropyl-phosphorylated human butyrylcholinesterase.
The Biochemical journal 1997;327 ( Pt 2)():601-7.
1997: A Weingand-Ziadé; Frédérique Renault; Patrick Masson
Combined pressure/heat-induced inactivation of butyrylcholinesterase.
Biochimica et biophysica acta 1997;1340(2):245-52.
1997: Patrick Masson; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase.
The Biochemical journal 1997;325 ( Pt 1)():53-61.
1997: Patrick Masson; P Legrand; Cynthia F Bartels; Marie-Thérèse Froment; Lawrence M Schopfer; Oksana Lockridge
Role of aspartate 70 and tryptophan 82 in binding of succinyldithiocholine to human butyrylcholinesterase.
Biochemistry 1997;36(8):2266-77.
1997: Oksana Lockridge; R M Blong; Patrick Masson; Marie-Thérèse Froment; Charles B Millard; Clarence A Broomfield
A single amino acid substitution, Gly117His, confers phosphotriesterase (organophosphorus acid anhydride hydrolase) activity on human butyrylcholinesterase.
Biochemistry 1997;36(4):786-95.
1996: Patrick Masson; Marie-Thérèse Froment; Cynthia F Bartels; Oksana Lockridge
Asp7O in the peripheral anionic site of human butyrylcholinesterase.
European journal of biochemistry / FEBS 1996;235(1-2):36-48.
1995: C Cléry; Frédérique Renault; Patrick Masson
Pressure-induced molten globule state of cholinesterase.
FEBS letters 1995;370(3):212-4.
1995: C Cléry; I Heiber-Langer; L Channac; L David; Claude Balny; Patrick Masson
Substrate dependence of amiloride- and soman-induced conformation changes of butyrylcholinesterase as evidenced by high-pressure perturbation.
Biochimica et biophysica acta 1995;1250(1):19-28.
1994: M Kris; O Jbilo; Cynthia F Bartels; Patrick Masson; S Rhode; Oksana Lockridge
Endogenous butyrylcholinesterase in SV40 transformed cell lines: COS-1, COS-7, MRC-5 SV40, and WI-38 VA13.
In vitro cellular & developmental biology. Animal 1994;30A(10):680-9.
1994: C Curtil; L Channac; C Ebel; Patrick Masson
Cold-induced conformational changes of ribonuclease A as investigated by subzero transverse temperature gradient gel electrophoresis.
Biochimica et biophysica acta 1994;1208(1):1-7.
1994: Patrick Masson; Marie-Thérèse Froment; R C Sorenson; Cynthia F Bartels; Oksana Lockridge
Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme.
Blood 1994;83(10):3003-5.
1993: Patrick Masson; S Adkins; Patrice Gouet; Oksana Lockridge
Recombinant human butyrylcholinesterase G390V, the fluoride-2 variant, expressed in Chinese hamster ovary cells, is a low affinity variant.
The Journal of biological chemistry 1993;268(19):14329-41.
1993: C Curtil; Patrick Masson
[Aging of cholinesterase after inhibition by organophosphates].
Annales pharmaceutiques françaises 1993;51(2):63-77.
1992: C Cléry; Patrick Masson; I Heiber-Langer; Claude Balny
Soman inhibition of butyrylcholinesterase in the presence of substrate: pressure and temperature perturbations.
Biochimica et biophysica acta 1992;1159(3):295-302.
1991: Martine Arpagaus; Arnaud Chatonnet; Patrick Masson; M Newton; T A Vaughan; Cynthia F Bartels; C P Nogueira; Bert N La Du; Oksana Lockridge
Use of the polymerase chain reaction for homology probing of butyrylcholinesterase from several vertebrates.
The Journal of biological chemistry 1991;266(11):6966-74.
1991: Patrick Masson
Structural and functional investigations of cholinesterases by means of affinity electrophoresis.
Cellular and molecular neurobiology 1991;11(1):173-89.
1990: Patrick Masson; Claude Balny
Conformational plasticity of butyrylcholinesterase as revealed by high pressure experiments.
Biochimica et biophysica acta 1990;1041(3):223-31.
1990: Patrick Masson; Arnaud Chatonnet; Oksana Lockridge
Evidence for a single butyrylcholinesterase gene in individuals carrying the C5 plasma cholinesterase variant (CHE2).
FEBS letters 1990;262(1):115-8.
1990: Patrick Masson; David M Arciero; Alan B Hooper; Claude Balny
Electrophoresis at elevated hydrostatic pressure of the multiheme hydroxylamine oxidoreductase.
Electrophoresis 1990;11(2):128-33.
1989: Patrick Masson
A naturally occurring molecular form of human plasma cholinesterase is an albumin conjugate.
Biochimica et biophysica acta 1989;998(3):258-66.