Colin Masters

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Evered Lisbeth A; Silbert Brendan S; Scott David A; Maruff Paul; Laughton Katrina M; Volitakis Irene; Cowie Tiffany; Cherny Robert A; Masters Colin L; Li Qiao-Xin
Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery.
Price Katherine Ann; Caragounis Aphrodite; Paterson Brett M; Filiz Gulay; Volitakis Irene; Masters Colin L; Barnham Kevin J; Donnelly Paul S; Crouch Peter J; White Anthony R
Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity.
Lewis Victoria; Hill Andrew F; Haigh Cathryn L; Klug Genevieve M; Masters Colin L; Lawson Victoria A; Collins Steven J
Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection.

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All Publications

2009: Evered Lisbeth A; Silbert Brendan S; Scott David A; Maruff Paul; Laughton Katrina M; Volitakis Irene; Cowie Tiffany; Cherny Robert A; Masters Colin L; Li Qiao-Xin
Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery.
The Annals of thoracic surgery 2009;88(5):1426-32.
2009: Price Katherine Ann; Caragounis Aphrodite; Paterson Brett M; Filiz Gulay; Volitakis Irene; Masters Colin L; Barnham Kevin J; Donnelly Paul S; Crouch Peter J; White Anthony R
Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity.
Journal of medicinal chemistry 2009;52(21):6606-20.
2009: Lewis Victoria; Hill Andrew F; Haigh Cathryn L; Klug Genevieve M; Masters Colin L; Lawson Victoria A; Collins Steven J
Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection.
Journal of neuropathology and experimental neurology 2009;68(10):1125-35.
2009: Tinsley Rogan B; Bye Chris R; Parish Clare L; Tziotis-Vais Angela; George Sonia; Culvenor Janetta G; Li Qiao-Xin; Masters Colin L; Finkelstein David I; Horne Malcolm K
Dopamine D2 receptor knockout mice develop features of Parkinson disease.
Annals of neurology 2009;66(4):472-84.
2009: Haigh Cathryn L; Lewis Victoria A; Vella Laura J; Masters Colin L; Hill Andrew F; Lawson Victoria A; Collins Steven J
PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site.
Cell research 2009;19(9):1062-78.
2009: Fodero-Tavoletti Michelle T; Mulligan Rachel S; Okamura Nobuyuki; Furumoto Shozo; Rowe Christopher C; Kudo Yukitsuka; Masters Colin L; Cappai Roberto; Yanai Kazuhiko; Villemagne Victor L
In vitro characterisation of BF227 binding to alpha-synuclein/Lewy bodies.
European journal of pharmacology 2009;617(1-3):54-8.
2009: Dutescu R Michael; Li Qiao-Xin; Crowston Jonathan; Masters Colin L; Baird Paul N; Culvenor Janetta G
Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(9):1213-21.
2009: Drew Simon C; Masters Colin L; Barnham Kevin J
Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.
Journal of the American Chemical Society 2009;131(25):8760-1.
2009: Maynard Christa J; Cappai Roberto; Volitakis Irene; Laughton Katrina M; Masters Colin L; Bush Ashley I; Li Qiao-Xin
Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice.
Cellular and molecular neurobiology 2009;29(5):757-67.
2009: Klug Genevieve M; Boyd Alison; Lewis Victoria; McGlade Amelia; Stehmann Christiane; Masters Colin L; Collins Steven J
Surveillance of Creutzfeldt-Jakob disease in Australia: 2009 update.
Communicable diseases intelligence 2009;33(2):188-91.
2009: Haigh Cathryn L; Drew Simon C; Boland Martin P; Masters Colin L; Barnham Kevin J; Lawson Victoria A; Collins Steven J
Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.
Journal of cell science 2009;122(Pt 10):1518-28.
2009: Leong Su Ling; Pham Chi L L; Galatis Denise; Fodero-Tavoletti Michelle T; Perez Keyla; Hill Andrew F; Masters Colin L; Ali Feda E; Barnham Kevin J; Cappai Roberto
Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation.
Free radical biology & medicine 2009;46(10):1328-37.
2009: Adlard Paul A; James Simon A; Bush Ashley I; Masters Colin L
beta-Amyloid as a molecular therapeutic target in Alzheimer's disease.
Drugs of today (Barcelona, Spain : 1998) 2009;45(4):293-304.
2009: Crouch Peter J; Tew Deborah J; Du Tai; Nguyen Diem Ngoc; Caragounis Aphrodite; Filiz Gulay; Blake Rachel E; Trounce Ian A; Soon Cynthia P W; Laughton Katrina; Perez Keyla A; Li Qiao-Xin; Cherny Robert A; Masters Colin L; Barnham Kevin J; White Anthony R
Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
Journal of neurochemistry 2009;108(5):1198-207.
2009: Robert Remy; Dolezal Olan; Waddington Lynne; Hattarki Meghan K; Cappai Roberto; Masters Colin L; Hudson Peter J; Wark Kim L
Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.
Protein engineering, design & selection : PEDS 2009;22(3):199-208.
2009: Brazier Marcus W; Wall Vanessa A; Brazier Barry W; Masters Colin L; Collins Steven J
Therapeutic interventions ameliorating prion disease.
Expert review of anti-infective therapy 2009;7(1):83-105.
2009: Price Katherine A; Crouch Peter J; Donnelly Paul S; Masters Colin L; White Anthony R; Curtain Cyril C
Membrane-targeted strategies for modulating APP and Abeta-mediated toxicity.
Journal of cellular and molecular medicine 2009;13(2):249-61.
2009: Fodero-Tavoletti Michelle T; Rowe Christopher C; McLean Catriona A; Leone Laura; Li Qiao-Xin; Masters Colin L; Cappai Roberto; Villemagne Victor L
Characterization of PiB binding to white matter in Alzheimer disease and other dementias.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(2):198-204.
2009: Klug Genevieve M; Wand Handan; Boyd Alison; Law Matthew; Whyte Scott; Kaldor John; Masters Colin L; Collins Steven
Enhanced geographically restricted surveillance simulates sporadic Creutzfeldt-Jakob disease cluster.
Brain : a journal of neurology 2009;132(Pt 2):493-501.
2009: Crouch Peter J; Hung Lin Wai; Adlard Paul A; Cortes Mikhalina; Lal Varsha; Filiz Gulay; Perez Keyla A; Nurjono Milawaty; Caragounis Aphrodite; Du Tai; Laughton Katrina; Volitakis Irene; Bush Ashley I; Li Qiao-Xin; Masters Colin L; Cappai Roberto; Cherny Robert A; Donnelly Paul S; White Anthony R; Barnham Kevin J
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):381-6.
2009: Drew Simon C; Noble Christopher J; Masters Colin L; Hanson Graeme R; Barnham Kevin J
Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide.
Journal of the American Chemical Society 2009;131(3):1195-207.
2009: Bellingham Shayne A; Coleman Louise A; Masters Colin L; Camakaris James; Hill Andrew F
Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.
The Journal of biological chemistry 2009;284(2):1291-301.
2008: Hung Lin Wai; Ciccotosto Giuseppe D; Giannakis Eleni; Tew Deborah J; Perez Keyla; Masters Colin L; Cappai Roberto; Wade John D; Barnham Kevin J
Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(46):11950-8.
2008: Raniga Parnesh; Bourgeat Pierrick; Fripp Jurgen; Acosta Oscar; Villemagne Victor L; Rowe Christopher; Masters Colin L; Jones Gareth; O'Keefe Graeme; Salvado Olivier; Ourselin Sébastien
Automated (11)C-PiB standardized uptake value ratio.
Academic radiology 2008;15(11):1376-89.
2008: Fripp Jurgen; Bourgeat Pierrick; Acosta Oscar; Raniga Parnesh; Modat Marc; Pike Kerryn E; Jones Gareth; O'Keefe Graeme; Masters Colin L; Ames David; Ellis Kathryn A; Maruff Paul; Currie Jon; Villemagne Victor L; Rowe Christopher C; Salvado Olivier; Ourselin Sébastien
Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging.
NeuroImage 2008;43(3):430-9.
2008: Streltsov Victor A; Titmuss Stephen J; Epa V Chandana; Barnham Kevin J; Masters Colin L; Varghese Joseph N
The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.
Biophysical journal 2008;95(7):3447-56.
2008: Lannfelt Lars; Blennow Kaj; Zetterberg Henrik; Batsman Stellan; Ames David; Harrison John; Masters Colin L; Targum Steve; Bush Ashley I; Murdoch Ross; Wilson Janet; Ritchie Craig W;
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial.
Lancet neurology 2008;7(9):779-86.
2008: Villemagne Victor L; Fodero-Tavoletti Michelle T; Pike Kerryn E; Cappai Roberto; Masters Colin L; Rowe Christopher C
The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias.
Molecular neurobiology 2008;38(1):1-15.
2008: Adlard Paul A; Cherny Robert A; Finkelstein David I; Gautier Elisabeth; Robb Elysia; Cortes Mikhalina; Volitakis Irene; Liu Xiang; Smith Jeffrey P; Perez Keyla; Laughton Katrina; Li Qiao-Xin; Charman Susan A; Nicolazzo Joseph A; Wilkins Simon; Deleva Karolina; Lynch Toni; Kok Gaik; Ritchie Craig W; Tanzi Rudolph E; Cappai Roberto; Masters Colin L; Barnham Kevin J; Bush Ashley I
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Neuron 2008;59(1):43-55.
2008: Brazier Marcus W; Doctrow Susan R; Masters Colin L; Collins Steven J
A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease.
Free radical biology & medicine 2008;45(2):184-92.
2008: Klug Genevieve M; Boyd Alison; Lewis Victoria; McGlade Amelia R; Roberts Helene; Douglass Samantha L; Masters Colin L; Collins Steven J
Surveillance of Creutzfeldt-Jakob disease in Australia: 2008.
Communicable diseases intelligence 2008;32(2):232-6.
2008: Drew Simon C; Leong Su Ling; Pham Chi L L; Tew Deborah J; Masters Colin L; Miles Luke A; Cappai Roberto; Barnham Kevin J
Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy.
Journal of the American Chemical Society 2008;130(24):7766-73.
2008: Barnham Kevin J; Kenche Vijaya B; Ciccotosto Giuseppe D; Smith David P; Tew Deborah J; Liu Xiang; Perez Keyla; Cranston Greg A; Johanssen Timothy J; Volitakis Irene; Bush Ashley I; Masters Colin L; White Anthony R; Smith Jeffrey P; Cherny Robert A; Cappai Roberto
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6813-8.
2008: Wun Kwok S; Miles Luke A; Crespi Gabriela A N; Wycherley Kaye; Ascher David B; Barnham Kevin J; Cappai Roberto; Beyreuther Konrad; Masters Colin L; Parker Michael W; McKinstry William J
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):438-41.
2008: Du Tai; La Fontaine Sharon L; Abdo Michael; Bellingham Shayne A; Greenough Mark; Volitakis Irene; Cherny Robert A; Bush Ashley I; Hudson Peter J; Camakaris James; Mercer Julian F; Crouch Peter J; Masters Colin L; Perreau Victoria M; White Anthony R
Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays.
Proteomics 2008;8(9):1819-31.
2008: Sharples Robyn A; Vella Laura J; Nisbet Rebecca M; Naylor Ryan; Perez Keyla; Barnham Kevin J; Masters Colin L; Hill Andrew F
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1469-78.
2008: George Sonia; van den Buuse Maarten; San Mok Su; Masters Colin L; Li Qiao-Xin; Culvenor Janetta G
Alpha-synuclein transgenic mice exhibit reduced anxiety-like behaviour.
Experimental neurology 2008;210(2):788-92.
2008: Giannakis Eleni; Pacífico Jessica; Smith David P; Hung Lin Wai; Masters Colin L; Cappai Roberto; Wade John D; Barnham Kevin J
Dimeric structures of alpha-synuclein bind preferentially to lipid membranes.
Biochimica et biophysica acta 2008;1778(4):1112-9.
2008: Tew Deborah J; Bottomley Stephen P; Smith David P; Ciccotosto Giuseppe D; Babon Jeffrey; Hinds Mark G; Masters Colin L; Cappai Roberto; Barnham Kevin J
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide.
Biophysical journal 2008;94(7):2752-66.
2008: Miles Luke A; Wun Kwok S; Crespi Gabriela A N; Fodero-Tavoletti Michelle T; Galatis Denise; Bagley Christopher J; Beyreuther Konrad; Masters Colin L; Cappai Roberto; McKinstry William J; Barnham Kevin J; Parker Michael W
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
Journal of molecular biology 2008;377(1):181-92.
2008: Weaver Cargin J; Collie A; Masters C; Maruff P
The nature of cognitive complaints in healthy older adults with and without objective memory decline.
Journal of clinical and experimental neuropsychology 2008;30(2):245-57.
2008: Rowe Christopher C; Ackerman Uwe; Browne William; Mulligan Rachel; Pike Kerryn L; O'Keefe Graeme; Tochon-Danguy Henry; Chan Gordon; Berlangieri Salvatore U; Jones Gareth; Dickinson-Rowe Kerryn L; Kung Hank P; Zhang Wei; Kung Mei Ping; Skovronsky Daniel; Dyrks Thomas; Holl Gerhard; Krause Sabine; Friebe Matthias; Lehman Lutz; Lindemann Stefanie; Dinkelborg Ludger M; Masters Colin L; Villemagne Victor L
Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism.
Lancet neurology 2008;7(2):129-35.
2008: Smith David P; Tew Deborah J; Hill Andrew F; Bottomley Stephen P; Masters Colin L; Barnham Kevin J; Cappai Roberto
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.
Biochemistry 2008;47(5):1425-34.
2008: Donnelly Paul S; Caragounis Aphrodite; Du Tai; Laughton Katrina M; Volitakis Irene; Cherny Robert A; Sharples Robyn A; Hill Andrew F; Li Qiao-Xin; Masters Colin L; Barnham Kevin J; White Anthony R
Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.
The Journal of biological chemistry 2008;283(8):4568-77.
2008: Du Tai; Ciccotosto Giuseppe D; Cranston Greg A; Kocak Gulcan; Masters Colin L; Crouch Peter J; Cappai Roberto; White Anthony R
Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation.
Free radical biology & medicine 2008;44(1):44-55.
2008: Lawson Victoria A; Vella Laura J; Stewart James D; Sharples Robyn A; Klemm Helen; Machalek Dorothy M; Masters Colin L; Cappai Roberto; Collins Steven J; Hill Andrew F
Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.
The international journal of biochemistry & cell biology 2008;40(12):2793-801.
2008: Price Katherine A; Filiz Gulay; Caragounis Aphrodite; Du Tai; Laughton Katrina M; Masters Colin L; Sharples Robyn A; Hill Andrew F; Li Qiao-Xin; Donnelly Paul S; Barnham Kevin J; Crouch Peter J; White Anthony R
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
The international journal of biochemistry & cell biology 2008;40(9):1901-17.
2008: Villemagne V L; Pike K E; Darby D; Maruff P; Savage G; Ng S; Ackermann U; Cowie T F; Currie J; Chan S G; Jones G; Tochon-Danguy H; O'Keefe G; Masters C L; Rowe C C
Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease.
Neuropsychologia 2008;46(6):1688-97.
2008: Filiz Gulay; Caragounis Aphrodite; Bica Laura; Du Tai; Masters Colin L; Crouch Peter J; White Anthony R
Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity.
The international journal of biochemistry & cell biology 2008;40(5):1030-42.
2008: Crouch Peter J; Harding Susan-Marie E; White Anthony R; Camakaris James; Bush Ashley I; Masters Colin L
Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease.
The international journal of biochemistry & cell biology 2008;40(2):181-98.
2007: Lau Tong-Lay; Gehman John D; Wade John D; Masters Colin L; Barnham Kevin J; Separovic Frances
Cholesterol and Clioquinol modulation of A beta(1-42) interaction with phospholipid bilayers and metals.
Biochimica et biophysica acta 2007;1768(12):3135-44.
2007: Pike Kerryn E; Savage Greg; Villemagne Victor L; Ng Steven; Moss Simon A; Maruff Paul; Mathis Chester A; Klunk William E; Masters Colin L; Rowe Christopher C
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.
Brain : a journal of neurology 2007;130(Pt 11):2837-44.
2007: Caragounis Aphrodite; Du Tai; Filiz Gulay; Laughton Katrina M; Volitakis Irene; Sharples Robyn A; Cherny Robert A; Masters Colin L; Drew Simon C; Hill Andrew F; Li Qiao-Xin; Crouch Peter J; Barnham Kevin J; White Anthony R
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
The Biochemical journal 2007;407(3):435-50.
2007: Cargin J Weaver; Maruff P; Collie A; Shafiq-Antonacci R; Masters C
Decline in verbal memory in non-demented older adults.
Journal of clinical and experimental neuropsychology 2007;29(7):706-18.
2007: Lawson Victoria A; Stewart James D; Masters Colin L
Enzymatic detergent treatment protocol that reduces protease-resistant prion protein load and infectivity from surgical-steel monofilaments contaminated with a human-derived prion strain.
The Journal of general virology 2007;88(Pt 10):2905-14.
2007: Lau Tong-Lay; Gehman John D; Wade John D; Perez Keyla; Masters Colin L; Barnham Kevin J; Separovic Frances
Membrane interactions and the effect of metal ions of the amyloidogenic fragment Abeta(25-35) in comparison to Abeta(1-42).
Biochimica et biophysica acta 2007;1768(10):2400-8.
2007: Vladimirtsev Vsevolod A; Nikitina Raisa S; Renwick Neil; Ivanova Anastasia A; Danilova Al'bina P; Platonov Fyodor A; Krivoshapkin Vadim G; McLean Catriona A; Masters Colin L; Gajdusek D Carleton; Goldfarb Lev G
Family clustering of Viliuisk encephalomyelitis in traditional and new geographic regions.
Emerging infectious diseases 2007;13(9):1321-6.
2007: Fodero-Tavoletti Michelle T; Smith David P; McLean Catriona A; Adlard Paul A; Barnham Kevin J; Foster Lisa E; Leone Laura; Perez Keyla; Cortés Mikhalina; Culvenor Janetta G; Li Qiao-Xin; Laughton Katrina M; Rowe Christopher C; Masters Colin L; Cappai Roberto; Villemagne Victor L
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(39):10365-71.
2007: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-Ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D
A primer of amyloid nomenclature.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(3):179-83.
2007: Ng Steven Y; Villemagne Victor L; Masters Colin L; Rowe Christopher C
Evaluating atypical dementia syndromes using positron emission tomography with carbon 11 labeled Pittsburgh Compound B.
Archives of neurology 2007;64(8):1140-4.
2007: Melrose H L; Kent C B; Taylor J P; Dachsel J C; Hinkle K M; Lincoln S J; Mok S S; Culvenor J G; Masters C L; Tyndall G M; Bass D I; Ahmed Z; Andorfer C A; Ross O A; Wszolek Z K; Delldonne A; Dickson D W; Farrer M J
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Neuroscience 2007;147(4):1047-58.
2007: Klug Genevieve M; Boyd Alison; Lewis Victoria; Douglass Samantha L; Roberts Helene; Argent Rebecca; Masters Colin L; Collins Steven J
Creutzfeldt-Jakob disease: Australian surveillance update to March 2007.
Communicable diseases intelligence 2007;31(2):194-7.
2007: Rowe C C; Ng S; Ackermann U; Gong S J; Pike K; Savage G; Cowie T F; Dickinson K L; Maruff P; Darby D; Smith C; Woodward M; Merory J; Tochon-Danguy H; O'Keefe G; Klunk W E; Mathis C A; Price J C; Masters C L; Villemagne V L
Imaging beta-amyloid burden in aging and dementia.
Neurology 2007;68(20):1718-25.
2007: Ng Steven; Villemagne Victor L; Berlangieri Sam; Lee Sze-Ting; Cherk Martin; Gong Sylvia J; Ackermann Uwe; Saunder Tim; Tochon-Danguy Henri; Jones Gareth; Smith Clare; O'Keefe Graeme; Masters Colin L; Rowe Christopher C
Visual assessment versus quantitative assessment of 11C-PIB PET and 18F-FDG PET for detection of Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(4):547-52.
2007: Vella L J; Sharples R A; Lawson V A; Masters C L; Cappai R; Hill A F
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
The Journal of pathology 2007;211(5):582-90.
2007: Li Qiao-Xin; Mok Su San; Laughton Katrina M; McLean Catriona A; Cappai Roberto; Masters Colin L; Culvenor Janetta G; Horne Malcolm K
Plasma alpha-synuclein is decreased in subjects with Parkinson's disease.
Experimental neurology 2007;204(2):583-8.
2007: Khalil Z; LoGiudice D; Khodr B; Maruff P; Masters C
Impaired peripheral endothelial microvascular responsiveness in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(1):25-32.
2007: Rowe D B; Lewis V; Needham M; Rodriguez M; Boyd A; McLean C; Roberts H; Masters C L; Collins S J
Novel prion protein gene mutation presenting with subacute PSP-like syndrome.
Neurology 2007;68(11):868-70.
2007: Smith David P; Ciccotosto Giuseppe D; Tew Deborah J; Fodero-Tavoletti Michelle T; Johanssen Timothy; Masters Colin L; Barnham Kevin J; Cappai Roberto
Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.
Biochemistry 2007;46(10):2881-91.
2007: Kong Geoffrey K-W; Adams Julian J; Harris Hugh H; Boas John F; Curtain Cyril C; Galatis Denise; Masters Colin L; Barnham Kevin J; McKinstry William J; Cappai Roberto; Parker Michael W
Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions.
Journal of molecular biology 2007;367(1):148-61.
2007: Melov Simon; Adlard Paul A; Morten Karl; Johnson Felicity; Golden Tamara R; Hinerfeld Doug; Schilling Birgit; Mavros Christine; Masters Colin L; Volitakis Irene; Li Qiao-Xin; Laughton Katrina; Hubbard Alan; Cherny Robert A; Gibson Brad; Bush Ashley I
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
PloS one 2007;2(6):e536.
2006: Masters Colin L; Beyreuther Konrad
Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway.
Brain : a journal of neurology 2006;129(Pt 11):2823-39.
2006: Sim Chou Hung; Lio Daisy Sio Seng; Mok Su San; Masters Colin L; Hill Andrew F; Culvenor Janetta G; Cheng Heung-Chin
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
Human molecular genetics 2006;15(21):3251-62.
2006: Crouch Peter J; Barnham Kevin J; Duce James A; Blake Rachel E; Masters Colin L; Trounce Ian A
Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide.
Journal of neurochemistry 2006;99(1):226-36.
2006: Collins S J; Sanchez-Juan P; Masters C L; Klug G M; van Duijn C; Poleggi A; Pocchiari M; Almonti S; Cuadrado-Corrales N; de Pedro-Cuesta J; Budka H; Gelpi E; Glatzel M; Tolnay M; Hewer E; Zerr I; Heinemann U; Kretszchmar H A; Jansen G H; Olsen E; Mitrova E; Alpérovitch A; Brandel J-P; Mackenzie J; Murray K; Will R G
Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology 2006;129(Pt 9):2278-87.
2006: Holsinger R M D; Lee J S; Boyd A; Masters C L; Collins S J
CSF BACE1 activity is increased in CJD and Alzheimer disease versus [corrected] other dementias.
Neurology 2006;67(4):710-2.
2006: Duce James A; Smith David P; Blake Rachel E; Crouch Peter J; Li Qiao-Xin; Masters Colin L; Trounce Ian A
Linker histone H1 binds to disease associated amyloid-like fibrils.
Journal of molecular biology 2006;361(3):493-505.
2006: Barnham Kevin J; Cappai Roberto; Beyreuther Konrad; Masters Colin L; Hill Andrew F
Delineating common molecular mechanisms in Alzheimer's and prion diseases.
Trends in biochemical sciences 2006;31(8):465-72.
2006: Koh Chor Hui Vivien; Whiteman Matthew; Li Qiao-Xin; Halliwell Barry; Jenner Andrew M; Wong Boon Seng; Laughton Katrina M; Wenk Markus; Masters Colin L; Beart Philip M; Bernard Ora; Cheung Nam Sang
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.
Journal of neurochemistry 2006;98(4):1278-89.
2006: Masters Colin L; Cappai Roberto; Barnham Kevin J; Villemagne Victor L
Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.
Journal of neurochemistry 2006;97(6):1700-25.
2006: White Anthony R; Du Tai; Laughton Katrina M; Volitakis Irene; Sharples Robyn A; Xilinas Michel E; Hoke David E; Holsinger R M Damian; Evin Geneviève; Cherny Robert A; Hill Andrew F; Barnham Kevin J; Li Qiao-Xin; Bush Ashley I; Masters Colin L
Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
The Journal of biological chemistry 2006;281(26):17670-80.
2006: Smith David P; Smith Danielle G; Curtain Cyril C; Boas John F; Pilbrow John R; Ciccotosto Giuseppe D; Lau Tong-Lay; Tew Deborah J; Perez Keyla; Wade John D; Bush Ashley I; Drew Simon C; Separovic Frances; Masters Colin L; Cappai Roberto; Barnham Kevin J
Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
The Journal of biological chemistry 2006;281(22):15145-54.
2006: Maynard Christa J; Cappai Roberto; Volitakis Irene; Cherny Robert A; Masters Colin L; Li Qiao-Xin; Bush Ashley I
Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology.
Journal of inorganic biochemistry 2006;100(5-6):952-62.
2006: Li Qiao-Xin; Mok Su San; Laughton Katrina M; McLean Catriona A; Volitakis Irene; Cherny Robert A; Cheung Nam Sang; White Anthony R; Masters Colin L
Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
Aging cell 2006;5(2):153-65.
2006: George Amee J; Holsinger R M Damian; McLean Catriona A; Tan Seong-Seng; Scott Hamish S; Cardamone Tina; Cappai Roberto; Masters Colin L; Li Qiao-Xin
Decreased phosphatidylethanolamine binding protein expression correlates with Abeta accumulation in the Tg2576 mouse model of Alzheimer's disease.
Neurobiology of aging 2006;27(4):614-23.
2006: Ritchie C W; Cappai R; Masters C
Clioquinol treatment in familiar early onset of Alzheimer's disease: Ibach B et al., Pharmacopsychiatry 2005; 38: 178-179.
Pharmacopsychiatry 2006;39(2):80.
2006: Weaver Cargin J; Maruff P; Collie A; Masters C
Mild memory impairment in healthy older adults is distinct from normal aging.
Brain and cognition 2006;60(2):146-55.
2006: Gralle Matthias; Oliveira Cristiano L P; Guerreiro Luiz H; McKinstry William J; Galatis Denise; Masters Colin L; Cappai Roberto; Parker Michael W; Ramos Carlos H I; Torriani Iris; Ferreira Sérgio T
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein.
Journal of molecular biology 2006;357(2):493-508.
2006: Andersen Olav M; Schmidt Vanessa; Spoelgen Robert; Gliemann Jørgen; Behlke Joachim; Galatis Denise; McKinstry William J; Parker Michael W; Masters Colin L; Hyman Bradley T; Cappai Roberto; Willnow Thomas E
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Biochemistry 2006;45(8):2618-28.
2006: Opazo Carlos; Luza Sandra; Villemagne Victor L; Volitakis Irene; Rowe Christopher; Barnham Kevin J; Strozyk Dorothea; Masters Colin L; Cherny Robert A; Bush Ashley I
Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease.
Aging cell 2006;5(1):69-79.
2006: Lau Tong-Lay; Ambroggio Ernesto E; Tew Deborah J; Cappai Roberto; Masters Colin L; Fidelio Gerardo D; Barnham Kevin J; Separovic Frances
Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.
Journal of molecular biology 2006;356(3):759-70.
2006: Brazier Marcus W; Lewis Victoria; Ciccotosto Giuseppe D; Klug Genevieve M; Lawson Victoria A; Cappai Roberto; Ironside James W; Masters Colin L; Hill Andrew F; White Anthony R; Collins Steven
Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease.
Brain research bulletin 2006;68(5):346-54.
2006: Mok Su San; Losic Dusan; Barrow Colin J; Turner Bradley J; Masters Colin L; Martin Lisandra L; Small David H
The beta-amyloid peptide of Alzheimer's disease decreases adhesion of vascular smooth muscle cells to the basement membrane.
Journal of neurochemistry 2006;96(1):53-64.
2006: Masters Colin L; Beyreuther Konrad
Pathways to the discovery of the Abeta amyloid of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):155-61.
2006: Evin Geneviève; Sernee Marijke Fleur; Masters Colin L
Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies.
CNS drugs 2006;20(5):351-72.
2006: Klug Genevieve M; Boyd Alison; Lewis Victoria; Douglass Samantha L; Argent Rebecca; Lee James S; Masters Colin L; Collins Steven J;
Creutzfeldt-Jakob disease: Australian surveillance update to December 2005.
Communicable diseases intelligence 2006;30(1):144-7.
2005: Yuan Fang F; Biffin Sandra; Brazier Marcus W; Suarez Monica; Cappai Roberto; Hill Andrew F; Collins Steven J; Sullivan John S; Middleton Deborah; Multhaup Gerd; Geczy Andrew F; Masters Colin L
Detection of prion epitopes on PrP and PrP of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP.
Immunology and cell biology 2005;83(6):632-7.
2005: Duncan R E; Delatycki M B; Collins S J; Boyd A; Masters C L; Savulescu J
Ethical considerations in presymptomatic testing for variant CJD.
Journal of medical ethics 2005;31(11):625-30.
2005: Hoke David E; Tan Jiang-Li; Ilaya Nancy T; Culvenor Janetta G; Smith Stephanie J; White Anthony R; Masters Colin L; Evin Geneviève M
In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
The FEBS journal 2005;272(21):5544-57.
2005: Collins Steven J; Lewis Victoria; Brazier Marcus W; Hill Andrew F; Lawson Victoria A; Klug Genevieve M; Masters Colin L
Extended period of asymptomatic prion disease after low dose inoculation: assessment of detection methods and implications for infection control.
Neurobiology of disease 2005;20(2):336-46.
2005: Soba Peter; Eggert Simone; Wagner Katja; Zentgraf Hanswalter; Siehl Katjuscha; Kreger Sylvia; Löwer Alexander; Langer Andreas; Merdes Gunter; Paro Renato; Masters Colin L; Müller Ulrike; Kins Stefan; Beyreuther Konrad
Homo- and heterodimerization of APP family members promotes intercellular adhesion.
The EMBO journal 2005;24(20):3624-34.
2005: Andersen Olav M; Reiche Juliane; Schmidt Vanessa; Gotthardt Michael; Spoelgen Robert; Behlke Joachim; von Arnim Christine A F; Breiderhoff Tilman; Jansen Pernille; Wu Xin; Bales Kelly R; Cappai Roberto; Masters Colin L; Gliemann Jørgen; Mufson Elliott J; Hyman Bradley T; Paul Steven M; Nykjaer Anders; Willnow Thomas E
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13461-6.
2005: Yarovaya Natalia; Schot Rachel; Fodero Lisa; McMahon Michelle; Mahoney Alexis; Williams Rachael; Verbeek Elly; de Bondt An; Hampson Mark; van der Spek Peter; Stubbs Andrew; Masters Colin L; Verheijen Frans W; Mancini Grazia M S; Venter Deon J
Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated.
Neurobiology of disease 2005;19(3):351-65.
2005: Cappai Roberto; Leck Su-Ling; Tew Deborah J; Williamson Nicholas A; Smith David P; Galatis Denise; Sharples Robyn A; Curtain Cyril C; Ali Feda' E; Cherny Robert A; Culvenor Janetta G; Bottomley Stephen P; Masters Colin L; Barnham Kevin J; Hill Andrew F
Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1377-9.
2005: Lewis V; Hill A F; Klug G M; Boyd A; Masters C L; Collins S J
Australian sporadic CJD analysis supports endogenous determinants of molecular-clinical profiles.
Neurology 2005;65(1):113-8.
2005: Maynard Christa J; Bush Ashley I; Masters Colin L; Cappai Roberto; Li Qiao-Xin
Metals and amyloid-beta in Alzheimer's disease.
International journal of experimental pathology 2005;86(3):147-59.
2005: Ali Feda E; Separovic Frances; Barrow Colin J; Cherny Robert A; Fraser Fiona; Bush Ashley I; Masters Colin L; Barnham Kevin J
Methionine regulates copper/hydrogen peroxide oxidation products of Abeta.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(6):353-60.
2005: Lawson Victoria A; Collins Steven J; Masters Colin L; Hill Andrew F
Prion protein glycosylation.
Journal of neurochemistry 2005;93(4):793-801.
2005: Villemagne Victor L; Rowe C C; Macfarlane S; Novakovic K E; Masters C L
Imaginem oblivionis: the prospects of neuroimaging for early detection of Alzheimer's disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005;12(3):221-30.
2005: Cappai Roberto; Cheng Fang; Ciccotosto Giuseppe D; Needham B Elise; Masters Colin L; Multhaup Gerd; Fransson Lars-Ake; Mani Katrin
The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
The Journal of biological chemistry 2005;280(14):13913-20.
2005: Tickler Anna K; Smith Danielle G; Ciccotosto Giuseppe D; Tew Deborah J; Curtain Cyril C; Carrington Darryl; Masters Colin L; Bush Ashley I; Cherny Robert A; Cappai Roberto; Wade John D; Barnham Kevin J
Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity.
The Journal of biological chemistry 2005;280(14):13355-63.
2005: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-Ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D;
Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(1):1-4.
2005: Evin Geneviève; Canterford Louise D; Hoke David E; Sharples Robyn A; Culvenor Janetta G; Masters Colin L
Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
Biochemistry 2005;44(11):4332-41.
2005: Kong Geoffrey K-W; Galatis Denise; Barnham Kevin J; Polekhina Galina; Adams Julian J; Masters Colin L; Cappai Roberto; Parker Michael W; McKinstry William J
Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):93-5.
2005: Crouch Peter J; Blake Rachel; Duce James A; Ciccotosto Giuseppe D; Li Qiao-Xin; Barnham Kevin J; Curtain Cyril C; Cherny Robert A; Cappai Roberto; Dyrks Thomas; Masters Colin L; Trounce Ian A
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(3):672-9.
2005: Novakovic K E; Villemagne V L; Rowe C C; Masters C L
Rare genetically defined causes of dementia.
International psychogeriatrics / IPA 2005;17 Suppl 1():S149-94.
2005: Klug Genevieve M; Boyd Alison; Lewis Victoria; Kvasnicka Madga; Lee James S; Masters Colin L; Collins Steven J
Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004.
Communicable diseases intelligence 2005;29(3):269-71.
2004: Turner Bradley J; Li Qiao-Xin; Laughton Katrina M; Masters Colin L; Lopes Elizabeth C; Atkin Julie D; Cheema Surindar S
Brain beta-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1.
Neurochemical research 2004;29(12):2281-6.
2004: Ritchie Craig W; Bush Ashley I; Masters Colin L
Metal-protein attenuating compounds and Alzheimer's disease.
Expert opinion on investigational drugs 2004;13(12):1585-92.
2004: Bellingham Shayne A; Ciccotosto Giuseppe D; Needham B Elise; Fodero Lisa R; White Anthony R; Masters Colin L; Cappai Roberto; Camakaris James
Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.
Journal of neurochemistry 2004;91(2):423-8.
2004: Ilaya Nancy T; Evin Geneviève; Masters Colin L; Culvenor Janetta G
Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
Journal of neurochemistry 2004;91(1):230-7.
2004: Ciccotosto Giuseppe D; Tew Deborah; Curtain Cyril C; Smith Danielle; Carrington Darryl; Masters Colin L; Bush Ashley I; Cherny Robert A; Cappai Roberto; Barnham Kevin J
Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution.
The Journal of biological chemistry 2004;279(41):42528-34.
2004: Barnham Kevin J; Haeffner Fredrik; Ciccotosto Giuseppe D; Curtain Cyril C; Tew Deborah; Mavros Christine; Beyreuther Konrad; Carrington Darryl; Masters Colin L; Cherny Robert A; Cappai Roberto; Bush Ashley I
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1427-9.
2004: Smith Margaret J; Sharples Robyn A; Evin Geneviève; McLean Catriona A; Dean Brian; Pavey Geoff; Fantino Emmanuelle; Cotton Richard G H; Imaizumi Kazunori; Masters Colin L; Cappai Roberto; Culvenor Janetta G
Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex.
Brain research. Molecular brain research 2004;127(1-2):128-35.
2004: Rekas Agata; Adda Christopher G; Andrew Aquilina J; Barnham Kevin J; Sunde Margaret; Galatis Denise; Williamson Nicholas A; Masters Colin L; Anders Robin F; Robinson Carol V; Cappai Roberto; Carver John A
Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.
Journal of molecular biology 2004;340(5):1167-83.
2004: George Amee J; Holsinger R M Damian; McLean Catriona A; Laughton Katrina M; Beyreuther Konrad; Evin Genevieve; Masters Colin L; Li Qiao-Xin
APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.
Neurobiology of disease 2004;16(1):124-32.
2004: Holsinger R M Damian; McLean Catriona A; Collins Steven J; Masters Colin L; Evin Geneviève
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
Annals of neurology 2004;55(6):898-9.
2004: Yao Shenggen; Cherny Robert A; Bush Ashley I; Masters Colin L; Barnham Kevin J
Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(4):210-7.
2004: Eggert Simone; Paliga Krzysztof; Soba Peter; Evin Genevieve; Masters Colin L; Weidemann Andreas; Beyreuther Konrad
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.
The Journal of biological chemistry 2004;279(18):18146-56.
2004: White Anthony R; Barnham Kevin J; Huang Xudong; Voltakis Irene; Beyreuther Konrad; Masters Colin L; Cherny Robert A; Bush Ashley I; Cappai Roberto
Iron inhibits neurotoxicity induced by trace copper and biological reductants.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(3):269-80.
2004: Barnham Kevin J; Masters Colin L; Bush Ashley I
Neurodegenerative diseases and oxidative stress.
Nature reviews. Drug discovery 2004;3(3):205-14.
2004: Brooke Fiona J; Boyd Alison; Klug Genevieve M; Masters Colin L; Collins Steven J
Lyodura use and the risk of iatrogenic Creutzfeldt-Jakob disease in Australia.
The Medical journal of Australia 2004;180(4):177-81.
2004: Collins Steven J; Lawson Victoria A; Masters Colin L
Transmissible spongiform encephalopathies.
Lancet 2004;363(9402):51-61.
2004: Culvenor Janetta G; Ilaya Nancy T; Ryan Michael T; Canterford Louise; Hoke David E; Williamson Nicholas A; McLean Catriona A; Masters Colin L; Evin Geneviève
Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.
European journal of biochemistry / FEBS 2004;271(2):375-85.
2004: Klug Genevieve M; Lewis Victoria; Boyd Alison; Lee James S; Masters Colin L; Collins Steven J
Creutzfeldt-Jakob disease surveillance in Australia January 1970 to December 2003.
Communicable diseases intelligence 2004;28(3):356-8.
2004: Maruff P; Collie A; Darby D; Weaver-Cargin J; Masters C; Currie Jon
Subtle memory decline over 12 months in mild cognitive impairment.
Dementia and geriatric cognitive disorders 2004;18(3-4):342-8.
2003: Ritchie Craig W; Bush Ashley I; Mackinnon Andrew; Macfarlane Steve; Mastwyk Maree; MacGregor Lachlan; Kiers Lyn; Cherny Robert; Li Qiao-Xin; Tammer Amanda; Carrington Darryl; Mavros Christine; Volitakis Irene; Xilinas Michel; Ames David; Davis Stephen; Beyreuther Konrad; Tanzi Rudolph E; Masters Colin L
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial.
Archives of neurology 2003;60(12):1685-91.
2003: Evin Geneviève; Zhu Aiqin; Holsinger R M Damian; Masters Colin L; Li Qiao-Xin
Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Journal of neuroscience research 2003;74(3):386-92.
2003: Nunan Janelle; Williamson Nicholas A; Hill Andrew F; Sernee M Fleur; Masters Colin L; Small David H
Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
Journal of neuroscience research 2003;74(3):378-85.
2003: Barnham Kevin J; Ciccotosto Giuseppe D; Tickler Anna K; Ali Feda E; Smith Danielle G; Williamson Nicholas A; Lam Yuen-Han; Carrington Darryl; Tew Deborah; Kocak Gulcan; Volitakis Irene; Separovic Frances; Barrow Colin J; Wade John D; Masters Colin L; Cherny Robert A; Curtain Cyril C; Bush Ashley I; Cappai Roberto
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.
The Journal of biological chemistry 2003;278(44):42959-65.
2003: Bahadi Randa; Farrelly Peter V; Kenna Bronwyn L; Curtain Cyril C; Masters Colin L; Cappai Roberto; Barnham Kevin J; Kourie Joseph I
Cu2+-induced modification of the kinetics of A beta(1-42) channels.
American journal of physiology. Cell physiology 2003;285(4):C873-80.
2003: Bush Ashley I; Masters Colin L; Tanzi Rudolph E
Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11193-4.
2003: Miklossy Judith; Taddei Kevin; Suva Domizio; Verdile Giuseppe; Fonte Justin; Fisher Christopher; Gnjec Anastazija; Ghika Joseph; Suard Françoise; Mehta Pankaj D; McLean Catriona A; Masters Colin L; Brooks William S; Martins Ralph N
Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.
Neurobiology of aging 2003;24(5):655-62.
2003: Green Alison J E; Sivtseva Tatiana M; Danilova Al'bina P; Osakovsky Vladimir L; Vladimirtsev Vsevolod A; Zeidler Martin; Knight Richard S; Platonov Feodor A; Shatunov Alexey; Alekseev Vasiliy P; Krivoshapkin Vadim G; Masters Colin L; Gajdusek D Carleton; Goldfarb Lev G
Viliuisk encephalomyelitis: intrathecal synthesis of oligoclonal IgG.
Journal of the neurological sciences 2003;212(1-2):69-73.
2003: Beher Dirk; Fricker Michael; Nadin Alan; Clarke Earl E; Wrigley Jonathan D J; Li Yue-Ming; Culvenor Janetta G; Masters Colin L; Harrison Timothy; Shearman Mark S
In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand.
Biochemistry 2003;42(27):8133-42.
2003: Kourie J I; Kenna B L; Tew D; Jobling M F; Curtain C C; Masters C L; Barnham K J; Cappai R
Copper modulation of ion channels of PrP[106-126] mutant prion peptide fragments.
The Journal of membrane biology 2003;193(1):35-45.
2003: Lewis V; Collins S; Hill A F; Boyd A; McLean C A; Smith M; Masters C L
Novel prion protein insert mutation associated with prolonged neurodegenerative illness.
Neurology 2003;60(10):1620-4.
2003: Barnham Kevin J; McKinstry William J; Multhaup Gerd; Galatis Denise; Morton Craig J; Curtain Cyril C; Williamson Nicholas A; White Anthony R; Hinds Mark G; Norton Raymond S; Beyreuther Konrad; Masters Colin L; Parker Michael W; Cappai Roberto
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
The Journal of biological chemistry 2003;278(19):17401-7.
2003: Goldstein Lee E; Muffat Julien A; Cherny Robert A; Moir Robert D; Ericsson Maria H; Huang Xudong; Mavros Christine; Coccia Jennifer A; Faget Kyle Y; Fitch Karlotta A; Masters Colin L; Tanzi Rudolph E; Chylack Leo T; Bush Ashley I
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease.
Lancet 2003;361(9365):1258-65.
2003: White Anthony R; Maher Fran; Brazier Marcus W; Jobling Michael F; Thyer James; Stewart Leanne R; Thompson Andrew; Gibson Riki; Masters Colin L; Multhaup Gerd; Beyreuther Konrad; Barrow Colin J; Collins Steven J; Cappai Roberto
Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.
Brain research 2003;966(2):231-44.
2003: Sernee M Fleur; Evin Geneviève; Culvenor Janetta G; Villadangos José A; Beyreuther Konrad; Masters Colin L; Cappai Roberto
Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage.
European journal of biochemistry / FEBS 2003;270(3):495-506.
2003: Grziwa Beate; Grimm Marcus O W; Masters Colin L; Beyreuther Konrad; Hartmann Tobias; Lichtenthaler Stefan F
The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted.
The Journal of biological chemistry 2003;278(9):6803-8.
2003: Curtain Cyril C; Ali Fedá E; Smith Danielle G; Bush Ashley I; Masters Colin L; Barnham Kevin J
Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid.
The Journal of biological chemistry 2003;278(5):2977-82.
2002: Lewis V; Boyd A; Masters C L; Collins S J
Apparently sporadic CJD and covert health-care transmissions.
Lancet neurology 2002;1(8):470-1.
2002: Khalil Zeinab; Poliviou Helen; Maynard Christa J; Beyreuther Konrad; Masters Colin L; Li Qiao-Xin
Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein.
Journal of Alzheimer's disease : JAD 2002;4(6):467-78.
2002: Collins S; Boyd A; Lee J S; Lewis V; Fletcher A; McLean C A; Law M; Kaldor J; Smith M J; Masters C L
Creutzfeldt-Jakob disease in Australia 1970-1999.
Neurology 2002;59(9):1365-71.
2002: Maynard Christa J; Cappai Roberto; Volitakis Irene; Cherny Robert A; White Anthony R; Beyreuther Konrad; Masters Colin L; Bush Ashley I; Li Qiao-Xin
Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.
The Journal of biological chemistry 2002;277(47):44670-6.
2002: Collins Steven J; Lewis Victoria; Brazier Marcus; Hill Andrew F; Fletcher Ashley; Masters Colin L
Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model.
Annals of neurology 2002;52(4):503-6.
2002: Opazo Carlos; Huang Xudong; Cherny Robert A; Moir Robert D; Roher Alex E; White Anthony R; Cappai Roberto; Masters Colin L; Tanzi Rudolph E; Inestrosa Nibaldo C; Bush Ashley I
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).
The Journal of biological chemistry 2002;277(43):40302-8.
2002: Westermark Per; Benson Merrill D; Buxbaum Joel N; Cohen Alan S; Frangione Blas; Ikeda Shu-ichi; Masters Colin L; Merlini Giampaolo; Saraiva Maria J; Sipe Jean D
Amyloid fibril protein nomenclature -- 2002.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2002;9(3):197-200.
2002: Tammer A H; Coia G; Cappai R; Fuller S; Masters C L; Hudson P; Underwood J R
Generation of a recombinant Fab antibody reactive with the Alzheimer's disease-related Abeta peptide.
Clinical and experimental immunology 2002;129(3):453-63.
2002: Li Qiao-Xin; Campbell Bruce C V; McLean Catriona A; Thyagarajan Domimic; Gai Wei-Ping; Kapsa Robert M; Beyreuther Konrad; Masters Colin L; Culvenor Janetta G
Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects.
Journal of Alzheimer's disease : JAD 2002;4(4):309-15.
2002: Culvenor Janetta G; Rietze Rodney L; Bartlett Perry F; Masters Colin L; Li Qiao-Xin
Oligodendrocytes from neural stem cells express alpha-synuclein: increased numbers from presenilin 1 deficient mice.
Neuroreport 2002;13(10):1305-8.
2002: Simons Andreas; Ruppert Thomas; Schmidt Carsten; Schlicksupp Andrea; Pipkorn Rüdiger; Reed Jennifer; Masters Colin L; White Anthony R; Cappai Roberto; Beyreuther Konrad; Bayer Thomas A; Multhaup Gerd
Evidence for a copper-binding superfamily of the amyloid precursor protein.
Biochemistry 2002;41(30):9310-20.
2002: Collins Steven; Boyd Alison; Fletcher Ashley; Kaldor John; Hill Andrew; Farish Stephen; McLean Catriona; Ansari Zahid; Smith Margaret; Masters Colin L
Creutzfeldt-Jakob disease cluster in an Australian rural city.
Annals of neurology 2002;52(1):115-8.
2002: Halliday G; Ng T; Rodriguez M; Harding A; Blumbergs P; Evans W; Fabian V; Fryer J; Gonzales M; Harper C; Kalnins R; Masters C L; McLean C; Milder D G; Pamphlett R; Scott G; Tannenberg A; Kril J
Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria.
Acta neuropathologica 2002;104(1):72-8.
2002: Holsinger R M Damian; McLean Catriona A; Beyreuther Konrad; Masters Colin L; Evin Geneviève
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.
Annals of neurology 2002;51(6):783-6.
2002: Mok Su San; Turner Bradley J; Beyreuther Konrad; Masters Colin L; Barrow Colin J; Small David H
Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine.
European journal of biochemistry / FEBS 2002;269(12):3014-22.
2002: Hamilton John A; Whitty Genevieve; White Anthony R; Jobling Michael F; Thompson Andrew; Barrow Colin J; Cappai Roberto; Beyreuther Konrad; Masters Colin L
Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).
Brain research 2002;940(1-2):49-54.
2002: Fodero Lisa R; Sáez-Valero Javier; McLean Catriona A; Martins Ralph N; Beyreuther Konrad; Masters Colin L; Robertson Terry A; Small David H
Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.
Journal of neurochemistry 2002;81(3):441-8.
2002: Evin Geneviève; Smith Margaret J; Tziotis Angela; McLean Catriona; Canterford Louise; Sharples Robyn A; Cappai Roberto; Weidemann Andreas; Beyreuther Konrad; Cotton Richard G H; Masters Colin L; Culvenor Janetta G
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(6):917-21.
2002: Evin Geneviève; Smith Margaret J; Tziotis Angela; McLean Catriona; Canterford Louise; Sharples Robyn A; Cappai Roberto; Weidemann Andreas; Beyreuther Konrad; Cotton Richard G H; Masters Colin L; Culvenor Janetta G
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(5):719-23.
2002: Filla A; De Michele G; Cocozza S; Patrignani A; Volpe G; Castaldo I; Ruggiero G; Bonavita V; Masters C; Casari G; Bruni A
Early onset autosomal dominant dementia with ataxia, extrapyramidal features, and epilepsy.
Neurology 2002;58(6):922-8.
2002: Weidemann Andreas; Eggert Simone; Reinhard Friedrich B M; Vogel Markus; Paliga Krzysztof; Baier Gottfried; Masters Colin L; Beyreuther Konrad; Evin Geneviève
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing.
Biochemistry 2002;41(8):2825-35.
2002: Lichtenthaler Stefan F; Beher Dirk; Grimm Heike S; Wang Rong; Shearman Mark S; Masters Colin L; Beyreuther Konrad
The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1365-70.
2002: White Anthony R; Multhaup Gerd; Galatis Denise; McKinstry William J; Parker Michael W; Pipkorn Rüdiger; Beyreuther Konrad; Masters Colin L; Cappai Roberto
Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(2):365-76.
2002: Laws S M; Hone E; Taddei K; Harper C; Dean B; McClean C; Masters C; Lautenschlager N; Gandy S E; Martins R N
Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein E.
Molecular psychiatry 2002;7(8):886-90.
2001: Chan S W; Collins S; Masters C L; Walker D M
Classical and variant Creutzfeldt-Jakob diseases and their potential impact on the practice of clinical dentistry in Australia.
Australian dental journal 2001;46(4):251-7.
2001: Boyd A; Fletcher A; Lee J S; Lewis V; Masters C L; Collins S J
Transmissible spongiform encephalopathies in Australia.
Communicable diseases intelligence 2001;25(4):248-52.
2001: Beher D; Wrigley J D; Nadin A; Evin G; Masters C L; Harrison T; Castro J L; Shearman M S
Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology.
The Journal of biological chemistry 2001;276(48):45394-402.
2001: Nunan J; Shearman M S; Checler F; Cappai R; Evin G; Beyreuther K; Masters C L; Small D H
The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
European journal of biochemistry / FEBS 2001;268(20):5329-36.
2001: Stewart L R; White A R; Jobling M F; Needham B E; Maher F; Thyer J; Beyreuther K; Masters C L; Collins S J; Cappai R
Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126.
Journal of neuroscience research 2001;65(6):565-72.
2001: Collins S; McLean C A; Masters C L
Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(5):387-97.
2001: Evin G; Sharples R A; Weidemann A; Reinhard F B; Carbone V; Culvenor J G; Holsinger R M; Sernee M F; Beyreuther K; Masters C L
Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.
Biochemistry 2001;40(28):8359-68.
2001: Jobling M F; Huang X; Stewart L R; Barnham K J; Curtain C; Volitakis I; Perugini M; White A R; Cherny R A; Masters C L; Barrow C J; Collins S J; Bush A I; Cappai R
Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.
Biochemistry 2001;40(27):8073-84.
2001: Fassbender K; Masters C; Beyreuther K
Alzheimer's disease: molecular concepts and therapeutic targets.
Die Naturwissenschaften 2001;88(6):261-7.
2001: Cherny R A; Atwood C S; Xilinas M E; Gray D N; Jones W D; McLean C A; Barnham K J; Volitakis I; Fraser F W; Kim Y; Huang X; Goldstein L E; Moir R D; Lim J T; Beyreuther K; Zheng H; Tanzi R E; Masters C L; Bush A I
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Neuron 2001;30(3):665-76.
2001: Collie A; Maruff P; Shafiq-Antonacci R; Smith M; Hallup M; Schofield P R; Masters C L; Currie J
Memory decline in healthy older people: implications for identifying mild cognitive impairment.
Neurology 2001;56(11):1533-8.
2001: Curtain C C; Ali F; Volitakis I; Cherny R A; Norton R S; Beyreuther K; Barrow C J; Masters C L; Bush A I; Barnham K J
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits.
The Journal of biological chemistry 2001;276(23):20466-73.
2001: Jayasena U L; Gribble S K; McKenzie A; Beyreuther K; Masters C L; Underwood J R
Identification of structural variations in the carboxyl terminus of Alzheimer's disease-associated beta A4[1-42] amyloid using a monoclonal antibody.
Clinical and experimental immunology 2001;124(2):297-305.
2001: Masters C L; Beyreuther K
The Worster-Drought syndrome and other syndromes of dementia with spastic paraparesis: the paradox of molecular pathology.
Journal of neuropathology and experimental neurology 2001;60(4):317-9.
2001: White A R; Guirguis R; Brazier M W; Jobling M F; Hill A F; Beyreuther K; Barrow C J; Masters C L; Collins S J; Cappai R
Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.
Neurobiology of disease 2001;8(2):299-316.
2001: White A R; Huang X; Jobling M F; Barrow C J; Beyreuther K; Masters C L; Bush A I; Cappai R
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
Journal of neurochemistry 2001;76(5):1509-20.
2001: Masters C L
The emerging European epidemic of variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: lessons for Australia.
The Medical journal of Australia 2001;174(4):160-1.
2001: Smith M J; Kwok J B; McLean C A; Kril J J; Broe G A; Nicholson G A; Cappai R; Hallupp M; Cotton R G; Masters C L; Schofield P R; Brooks W S
Variable phenotype of Alzheimer's disease with spastic paraparesis.
Annals of neurology 2001;49(1):125-9.
2001: Campbell B C; McLean C A; Culvenor J G; Gai W P; Blumbergs P C; Jäkälä P; Beyreuther K; Masters C L; Li Q X
The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease.
Journal of neurochemistry 2001;76(1):87-96.
2001: Yakubovskaya M G; Neschastnova A A; Humphrey K E; Babon J J; Popenko V I; Smith M J; Lambrinakos A; Lipatova Z V; Dobrovolskaia M A; Cappai R; Masters C L; Belitsky G A; Cotton R G
Interaction of linear homologous DNA duplexes via Holliday junction formation.
European journal of biochemistry / FEBS 2001;268(1):7-14.
2000: Thompson A; White A R; McLean C; Masters C L; Cappai R; Barrow C J
Amyloidogenicity and neurotoxicity of peptides corresponding to the helical regions of PrP(C).
Journal of neuroscience research 2000;62(2):293-301.
2000: Mok S S; Clippingdale A B; Beyreuther K; Masters C L; Barrow C J; Small D H
A beta peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture.
Journal of neuroscience research 2000;61(4):449-57.
2000: Collins S; Boyd A; Fletcher A; Byron K; Harper C; McLean C A; Masters C L
Novel prion protein gene mutation in an octogenarian with Creutzfeldt-Jakob disease.
Archives of neurology 2000;57(7):1058-63.
2000: Cherny R A; Barnham K J; Lynch T; Volitakis I; Li Q X; McLean C A; Multhaup G; Beyreuther K; Tanzi R E; Masters C L; Bush A I
Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.
Journal of structural biology 2000;130(2-3):209-16.
2000: Borchardt T; Schmidt C; Camarkis J; Cappai R; Masters C L; Beyreuther K; Multhaup G
Differential effects of zinc on amyloid precursor protein (APP) processing in copper-resistant variants of cultured Chinese hamster ovary cells.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(4):785-95.
2000: Campbell B C; Li Q X; Culvenor J G; Jäkälä P; Cappai R; Beyreuther K; Masters C L; McLean C A
Accumulation of insoluble alpha-synuclein in dementia with Lewy bodies.
Neurobiology of disease 2000;7(3):192-200.
2000: Fassbender K; Masters C; Beyreuther K
Alzheimer's disease: an inflammatory disease?
Neurobiology of aging 2000;21(3):433-6; discussion 451-3.
2000: Collins S; Boyd A; Fletcher A; Gonzales M; McLean C A; Byron K; Masters C L
Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2000;7(3):203-8.
2000: Collins S; Boyd A; Fletcher A; Gonzales M F; McLean C A; Masters C L
Recent advances in the pre-mortem diagnosis of Creutzfeldt-Jakob disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2000;7(3):195-202.
2000: Emilien G; Beyreuther K; Masters C L; Maloteaux J M
Prospects for pharmacological intervention in Alzheimer disease.
Archives of neurology 2000;57(4):454-9.
2000: Smith M J; Humphrey K E; Cappai R; Beyreuther K; Masters C L; Cotton R G
Correct heteroduplex formation for mutation detection analysis.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 2000;5(1):67-73.
2000: Culvenor J G; Evin G; Cooney M A; Wardan H; Sharples R A; Maher F; Reed G; Diehlmann A; Weidemann A; Beyreuther K; Masters C L
Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.
Experimental cell research 2000;255(2):192-206.
2000: Postuma R B; He W; Nunan J; Beyreuther K; Masters C L; Barrow C J; Small D H
Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures.
Journal of neurochemistry 2000;74(3):1122-30.
2000: Coulson E J; Paliga K; Beyreuther K; Masters C L
What the evolution of the amyloid protein precursor supergene family tells us about its function.
Neurochemistry international 2000;36(3):175-84.
2000: Emilien G; Maloteaux J M; Beyreuther K; Masters C L
Alzheimer disease: mouse models pave the way for therapeutic opportunities.
Archives of neurology 2000;57(2):176-81.
2000: Evin G; Le Brocque D; Culvenor J G; Galatis D; Weidemann A; Beyreuther K; Masters C L; Cappai R
Presenilin I expression in yeast lowers secretion of the amyloid precursor protein.
Neuroreport 2000;11(2):405-8.
2000: Kwok J B; Li Q X; Hallupp M; Whyte S; Ames D; Beyreuther K; Masters C L; Schofield P R
Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis.
Annals of neurology 2000;47(2):249-53.
2000: Bergsdorf C; Paliga K; Kreger S; Masters C L; Beyreuther K
Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA.
The Journal of biological chemistry 2000;275(3):2046-56.
2000: Masters C L; Beyreuther K
Genomic neurology.
Archives of neurology 2000;57(1):53.
1999: Huang X; Cuajungco M P; Atwood C S; Hartshorn M A; Tyndall J D; Hanson G R; Stokes K C; Leopold M; Multhaup G; Goldstein L E; Scarpa R C; Saunders A J; Lim J; Moir R D; Glabe C; Bowden E F; Masters C L; Fairlie D P; Tanzi R E; Bush A I
Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.
The Journal of biological chemistry 1999;274(52):37111-6.
1999: McLean C A; Cherny R A; Fraser F W; Fuller S J; Smith M J; Beyreuther K; Bush A I; Masters C L
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.
Annals of neurology 1999;46(6):860-6.
1999: Borchardt T; Camakaris J; Cappai R; Masters C L; Beyreuther K; Multhaup G
Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion.
The Biochemical journal 1999;344 Pt 2():461-7.
1999: Caswell M D; Mok S S; Henry A; Cappai R; Klug G; Beyreuther K; Masters C L; Small D H
The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.
European journal of biochemistry / FEBS 1999;266(2):509-16.
1999: Small D H; Clarris H L; Williamson T G; Reed G; Key B; Mok S S; Beyreuther K; Masters C L; Nurcombe V
Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 1999;1(4-5):275-85.
1999: Bayer T A; Cappai R; Masters C L; Beyreuther K; Multhaup G
It all sticks together--the APP-related family of proteins and Alzheimer's disease.
Molecular psychiatry 1999;4(6):524-8.
1999: Ojaimi J; Masters C L; Opeskin K; McKelvie P; Byrne E
Mitochondrial respiratory chain activity in the human brain as a function of age.
Mechanisms of ageing and development 1999;111(1):39-47.
1999: White A R; Collins S J; Maher F; Jobling M F; Stewart L R; Thyer J M; Beyreuther K; Masters C L; Cappai R
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity.
The American journal of pathology 1999;155(5):1723-30.
1999: White A R; Multhaup G; Maher F; Bellingham S; Camakaris J; Zheng H; Bush A I; Beyreuther K; Masters C L; Cappai R
The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9170-9.
1999: Li Q X; Fuller S J; Beyreuther K; Masters C L
The amyloid precursor protein of Alzheimer disease in human brain and blood.
Journal of leukocyte biology 1999;66(4):567-74.
1999: Culvenor J G; McLean C A; Cutt S; Campbell B C; Maher F; Jäkälä P; Hartmann T; Beyreuther K; Masters C L; Li Q X
Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.
The American journal of pathology 1999;155(4):1173-81.
1999: Ojaimi J; Masters C L; McLean C; Opeskin K; McKelvie P; Byrne E
Irregular distribution of cytochrome c oxidase protein subunits in aging and Alzheimer's disease.
Annals of neurology 1999;46(4):656-60.
1999: Jobling M F; Stewart L R; White A R; McLean C; Friedhuber A; Maher F; Beyreuther K; Masters C L; Barrow C J; Collins S J; Cappai R
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126.
Journal of neurochemistry 1999;73(4):1557-65.
1999: White A R; Reyes R; Mercer J F; Camakaris J; Zheng H; Bush A I; Multhaup G; Beyreuther K; Masters C L; Cappai R
Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice.
Brain research 1999;842(2):439-44.
1999: Cherny R A; Legg J T; McLean C A; Fairlie D P; Huang X; Atwood C S; Beyreuther K; Tanzi R E; Masters C L; Bush A I
Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.
The Journal of biological chemistry 1999;274(33):23223-8.
1999: Christie G; Markwell R E; Gray C W; Smith L; Godfrey F; Mansfield F; Wadsworth H; King R; McLaughlin M; Cooper D G; Ward R V; Howlett D R; Hartmann T; Lichtenthaler S F; Beyreuther K; Underwood J; Gribble S K; Cappai R; Masters C L; Tamaoka A; Gardner R L; Rivett A J; Karran E H; Allsop D
Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.
Journal of neurochemistry 1999;73(1):195-204.
1999: Masters C L; Beyreuther K
Amyloid Nomenclature Committee.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(2):151-2.
1999: Lichtenthaler S F; Multhaup G; Masters C L; Beyreuther K
A novel substrate for analyzing Alzheimer's disease gamma-secretase.
FEBS letters 1999;453(3):288-92.
1999: Li Q X; Maynard C; Cappai R; McLean C A; Cherny R A; Lynch T; Culvenor J G; Trevaskis J; Tanner J E; Bailey K A; Czech C; Bush A I; Beyreuther K; Masters C L
Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
Journal of neurochemistry 1999;72(6):2479-87.
1999: Bayer T A; Jäkälä P; Hartmann T; Havas L; McLean C; Culvenor J G; Li Q X; Masters C L; Falkai P; Beyreuther K
Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.
Neuroscience letters 1999;266(3):213-6.
1999: Diehlmann A; Ida N; Weggen S; Grünberg J; Haass C; Masters C L; Bayer T A; Beyreuther K
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Journal of neuroscience research 1999;56(4):405-19.
1999: White A R; Bush A I; Beyreuther K; Masters C L; Cappai R
Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione.
Journal of neurochemistry 1999;72(5):2092-8.
1999: Storey E; Katz M; Brickman Y; Beyreuther K; Masters C L
Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures.
The European journal of neuroscience 1999;11(5):1779-88.
1999: Rossjohn J; Cappai R; Feil S C; Henry A; McKinstry W J; Galatis D; Hesse L; Multhaup G; Beyreuther K; Masters C L; Parker M W
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
Nature structural biology 1999;6(4):327-31.
1999: Beher D; Elle C; Underwood J; Davis J B; Ward R; Karran E; Masters C L; Beyreuther K; Multhaup G
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.
Journal of neurochemistry 1999;72(4):1564-73.
1999: Westermark P; Araki S; Benson M D; Cohen A S; Frangione B; Masters C L; Saraiva M J; Sipe J D; Husby G; Kyle R A; Selkoe D
Nomenclature of amyloid fibril proteins. Report from the meeting of the International Nomenclature Committee on Amyloidosis, August 8-9, 1998. Part 1.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(1):63-6.
1999: Cappai R; Stewart L; Jobling M F; Thyer J M; White A R; Beyreuther K; Collins S J; Masters C L; Barrow C J
Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation.
Biochemistry 1999;38(11):3280-4.
1999: Lichtenthaler S F; Wang R; Grimm H; Uljon S N; Masters C L; Beyreuther K
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3053-8.
1999: Smith M J; Gardner R J; Knight M A; Forrest S M; Beyreuther K; Storey E; McLean C A; Cotton R G; Cappal R; Masters C L
Early-onset Alzheimer's disease caused by a novel mutation at codon 219 of the presenilin-1 gene.
Neuroreport 1999;10(3):503-7.
1999: Collins S; Law M G; Fletcher A; Boyd A; Kaldor J; Masters C L
Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study.
Lancet 1999;353(9154):693-7.
1999: Weidemann A; Paliga K; Dürrwang U; Reinhard F B; Schuckert O; Evin G; Masters C L
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.
The Journal of biological chemistry 1999;274(9):5823-9.
1999: Cappai R; Mok S S; Galatis D; Tucker D F; Henry A; Beyreuther K; Small D H; Masters C L
Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.
FEBS letters 1999;442(1):95-8.
1999: Multhaup G; Masters C L
Metal binding and radical generation of proteins in human neurological diseases and aging.
Metal ions in biological systems 1999;36():365-87.
1999: Multhaup G; Hesse L; Borchardt T; Ruppert T; Cappai R; Masters C L; Beyreuther K
Autoxidation of amyloid precursor protein and formation of reactive oxygen species.
Advances in experimental medicine and biology 1999;448():183-92.
1998: Henry A; Li Q X; Galatis D; Hesse L; Multhaup G; Beyreuther K; Masters C L; Cappai R
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
British journal of haematology 1998;103(2):402-15.
1998: Fossgreen A; Brückner B; Czech C; Masters C L; Beyreuther K; Paro R
Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13703-8.
1998: Taddei K; Kwok J B; Kril J J; Halliday G M; Creasey H; Hallupp M; Fisher C; Brooks W S; Chung C; Andrews C; Masters C L; Schofield P R; Martins R N
Two novel presenilin-1 mutations (Ser169Leu and Pro436Gln) associated with very early onset Alzheimer's disease.
Neuroreport 1998;9(14):3335-9.
1998: Le Brocque D; Henry A; Cappai R; Li Q X; Tanner J E; Galatis D; Gray C; Holmes S; Underwood J R; Beyreuther K; Masters C L; Evin G
Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
Biochemistry 1998;37(42):14958-65.
1998: White A R; Zheng H; Galatis D; Maher F; Hesse L; Multhaup G; Beyreuther K; Masters C L; Cappai R
Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(16):6207-17.
1998: Sberna G; Sáez-Valero J; Li Q X; Czech C; Beyreuther K; Masters C L; McLean C A; Small D H
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1998;71(2):723-31.
1998: McLean C A; Ironside J W; Alpers M P; Brown P W; Cervenakova L; Anderson R M; Masters C L
Comparative neuropathology of Kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype of host.
Brain pathology (Zurich, Switzerland) 1998;8(3):429-37.
1998: Culvenor J G; Henry A; Hartmann T; Evin G; Galatis D; Friedhuber A; Jayasena U L; Underwood J R; Beyreuther K; Masters C L; Cappai R
Subcellular localization of the Alzheimer's disease amyloid precursor protein and derived polypeptides expressed in a recombinant yeast system.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(2):79-89.
1998: Taddei K; Yang D; Fisher C; Clarnette R; Hallmayer J; Barnetson R; Maller R; Brooks W S; Whyte S; Nicholson G A; Masters C L; Broe G A; Gandy S E; Martins R N
No association of presenilin-1 intronic polymorphism and Alzheimer's disease in Australia.
Neuroscience letters 1998;246(3):178-80.
1998: Postuma R B; Martins R N; Cappai R; Beyreuther K; Masters C L; Strickland D K; Mok S S; Small D H
Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture.
FEBS letters 1998;428(1-2):13-6.
1998: Multhaup G; Ruppert T; Schlicksupp A; Hesse L; Bill E; Pipkorn R; Masters C L; Beyreuther K
Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide.
Biochemistry 1998;37(20):7224-30.
1998: Li Q X; Whyte S; Tanner J E; Evin G; Beyreuther K; Masters C L
Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets.
Laboratory investigation; a journal of technical methods and pathology 1998;78(4):461-9.
1998: Masters C L; Beyreuther K
Alzheimer's disease.
BMJ (Clinical research ed.) 1998;316(7129):446-8.
1998: Moir R D; Lynch T; Bush A I; Whyte S; Henry A; Portbury S; Multhaup G; Small D H; Tanzi R E; Beyreuther K; Masters C L
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
The Journal of biological chemistry 1998;273(9):5013-9.
1997: Paliga K; Peraus G; Kreger S; Dürrwang U; Hesse L; Multhaup G; Masters C L; Beyreuther K; Weidemann A
Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
European journal of biochemistry / FEBS 1997;250(2):354-63.
1997: Lichtenthaler S F; Ida N; Multhaup G; Masters C L; Beyreuther K
Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
Biochemistry 1997;36(49):15396-403.
1997: Schröder J; Pantel J; Ida N; Essig M; Hartmann T; Knopp M V; Schad L R; Sandbrink R; Sauer H; Masters C L; Beyreuther K
Cerebral changes and cerebrospinal fluid beta-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging.
Molecular psychiatry 1997;2(6):505-7.
1997: Coulson E J; Barrett G L; Storey E; Bartlett P F; Beyreuther K; Masters C L
Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.
Brain research 1997;770(1-2):72-80.
1997: Mok S S; Sberna G; Heffernan D; Cappai R; Galatis D; Clarris H J; Sawyer W H; Beyreuther K; Masters C L; Small D H
Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease.
FEBS letters 1997;415(3):303-7.
1997: Beyreuther K; Masters C L
Alzheimer's disease. The ins and outs of amyloid-beta.
Nature 1997;389(6652):677-8.
1997: Peraus G C; Masters C L; Beyreuther K
Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(20):7714-24.
1997: Multhaup G; Ruppert T; Schlicksupp A; Hesse L; Beher D; Masters C L; Beyreuther K
Reactive oxygen species and Alzheimer's disease.
Biochemical pharmacology 1997;54(5):533-9.
1997: Culvenor J G; Maher F; Evin G; Malchiodi-Albedi F; Cappai R; Underwood J R; Davis J B; Karran E H; Roberts G W; Beyreuther K; Masters C L
Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
Journal of neuroscience research 1997;49(6):719-31.
1997: Sáez-Valero J; Sberna G; McLean C A; Masters C L; Small D H
Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.
Lancet 1997;350(9082):929.
1997: Hartmann T; Bieger S C; Brühl B; Tienari P J; Ida N; Allsop D; Roberts G W; Masters C L; Dotti C G; Unsicker K; Beyreuther K
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.
Nature medicine 1997;3(9):1016-20.
1997: Sberna G; Sáez-Valero J; Beyreuther K; Masters C L; Small D H
The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells.
Journal of neurochemistry 1997;69(3):1177-84.
1997: McLean C A; Beyreuther K; Masters C L
Commentary on the consensus recommendations for the post mortem diagnosis of Alzheimer's disease.
Neurobiology of aging 1997;18(4 Suppl):S89-90.
1997: Masters C L; Beyreuther K
Spongiform encephalopathies. Tracking turncoat prion proteins.
Nature 1997;388(6639):228-9.
1997: Henry A; Masters C L; Beyreuther K; Cappai R
Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.
Protein expression and purification 1997;10(2):283-91.
1997: Beyreuther K; Masters C L
Serpents on the road to dementia and death. Accumulating evidence from several studies points to the normal function of presenilin 1 and suggests how the mutant protein contributes to deposition of amyloid plaques in Alzheimer's disease.
Nature medicine 1997;3(7):723-5.
1997: McLean C A; Masters C L; Vladimirtsev V A; Prokhorova I A; Goldfarb L G; Asher D M; Vladimirtsev A I; Alekseev V P; Gajdusek D C
Viliuisk encephalomyelitis--review of the spectrum of pathological changes.
Neuropathology and applied neurobiology 1997;23(3):212-7.
1997: Tienari P J; Ida N; Ikonen E; Simons M; Weidemann A; Multhaup G; Masters C L; Dotti C G; Beyreuther K
Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4125-30.
1997: Weidemann A; Paliga K; Dürrwang U; Czech C; Evin G; Masters C L; Beyreuther K
Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein.
Nature medicine 1997;3(3):328-32.
1997: Clarris H J; Cappai R; Heffernan D; Beyreuther K; Masters C L; Small D H
Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping.
Journal of neurochemistry 1997;68(3):1164-72.
1997: Whyte S; Wilson N; Currie J; Maruff P; Malone V; Shafiq-Antonacci R; Tyler P; Derry K L; Underwood J; Li Q X; Beyreuther K; Masters C L
Collection and normal levels of the amyloid precursor protein in plasma.
Annals of neurology 1997;41(1):121-4.
1997: Mok S S; Evin G; Li Q X; Smith A I; Beyreuther K; Masters C L; Small D H
A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.
Biochemistry 1997;36(1):156-63.
1997: Sandbrink R; Mönning U; Masters C L; Beyreuther K
Expression of the APP gene family in brain cells, brain development and aging.
Gerontology 1997;43(1-2):119-31.
1996: Williamson T G; Mok S S; Henry A; Cappai R; Lander A D; Nurcombe V; Beyreuther K; Masters C L; Small D H
Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth.
The Journal of biological chemistry 1996;271(49):31215-21.
1996: Storey E; Beyreuther K; Masters C L
Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components.
Brain research 1996;735(2):217-31.
1996: Tienari P J; De Strooper B; Ikonen E; Simons M; Weidemann A; Czech C; Hartmann T; Ida N; Multhaup G; Masters C L; Van Leuven F; Beyreuther K; Dotti C G
The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein.
The EMBO journal 1996;15(19):5218-29.
1996: Beyreuther K; Masters C L
Alzheimer's disease. Tangle disentanglement.
Nature 1996;383(6600):476-7.
1996: Storey E; Spurck T; Pickett-Heaps J; Beyreuther K; Masters C L
The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.
Brain research 1996;735(1):59-66.
1996: Ida N; Masters C L; Beyreuther K
Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells.
FEBS letters 1996;394(2):174-8.
1996: Ida N; Hartmann T; Pantel J; Schröder J; Zerfass R; Förstl H; Sandbrink R; Masters C L; Beyreuther K
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.
The Journal of biological chemistry 1996;271(37):22908-14.
1996: Sandbrink R; Zhang D; Schaeffer S; Masters C L; Bauer J; Förstl H; Beyreuther K
Missense mutations of the PS-1/S182 gene in German early-onset Alzheimer's disease patients.
Annals of neurology 1996;40(2):265-6.
1996: Masters C L
Emergence of a new variant of Creutzfeldt-Jakob disease in Europe?
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(3):203-4.
1996: Hartmann T; Bergsdorf C; Sandbrink R; Tienari P J; Multhaup G; Ida N; Bieger S; Dyrks T; Weidemann A; Masters C L; Beyreuther K
Alzheimer's disease betaA4 protein release and amyloid precursor protein sorting are regulated by alternative splicing.
The Journal of biological chemistry 1996;271(22):13208-14.
1996: Collins S; Masters C L
Iatrogenic and zoonotic Creutzfeldt-Jakob disease: the Australian perspective.
The Medical journal of Australia 1996;164(10):598-602.
1996: Simpson D A; Masters C L; Ohlrich G; Purdie G; Stuart G; Tannenberg A E
Iatrogenic Creutzfeldt-Jakob disease and its neurosurgical implications.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(2):118-23.
1996: Collins S J; Cappai R; Masters C L
Recent developments in the transmissible spongiform encephalopathies: Implications for clinical practice.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(2):97-101.
1996: Sandbrink R; Hartmann T; Masters C L; Beyreuther K
Genes contributing to Alzheimer's disease.
Molecular psychiatry 1996;1(1):27-40.
1996: Multhaup G; Schlicksupp A; Hesse L; Beher D; Ruppert T; Masters C L; Beyreuther K
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
Science (New York, N.Y.) 1996;271(5254):1406-9.
1996: Beyreuther K; Multhaup G; Mönning U; Sandbrink R; Beher D; Hesse L; Small D H; Masters C L
Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines.
Annals of the New York Academy of Sciences 1996;777():74-6.
1996: Small D H; Williamson T; Reed G; Clarris H; Beyreuther K; Masters C L; Nurcombe V
The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;777():316-21.
1996: Sandbrink R; Masters C L; Beyreuther K
APP gene family. Alternative splicing generates functionally related isoforms.
Annals of the New York Academy of Sciences 1996;777():281-7.
1996: Beher D; Hesse L; Masters C L; Multhaup G
Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.
The Journal of biological chemistry 1996;271(3):1613-20.
1996: Tienari P J; De Strooper B; Ikonen E; Ida N; Simons M; Masters C L; Dotti C G; Beyreuther K
Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.
Cold Spring Harbor symposia on quantitative biology 1996;61():575-85.
1996: Beyreuther K; Multhaup G; Masters C L
Alzheimer's disease: genesis of amyloid.
Ciba Foundation symposium 1996;199():119-27; discussion 127-31.
1995: LePage R N; Fosang A J; Fuller S J; Murphy G; Evin G; Beyreuther K; Masters C L; Small D H
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
FEBS letters 1995;377(2):267-70.
1995: Williamson T G; Nurcombe V; Beyreuther K; Masters C L; Small D H
Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1995;65(5):2201-8.
1995: Evin G; Cappai R; Li Q X; Culvenor J G; Small D H; Beyreuther K; Masters C L
Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D.
Biochemistry 1995;34(43):14185-92.
1995: Culvenor J G; Friedhuber A; Fuller S J; Beyreuther K; Masters C L
Expression of the amyloid precursor protein of Alzheimer's disease on the surface of transfected HeLa cells.
Experimental cell research 1995;220(2):474-81.
1995: Storey E; Masters C L
Amyloid, aluminium and the aetiology of Alzheimer's disease.
The Medical journal of Australia 1995;163(5):256-9.
1995: Clarris H J; Key B; Beyreuther K; Masters C L; Small D H
Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.
Brain research. Developmental brain research 1995;88(1):87-95.
1995: Multhaup G; Mechler H; Masters C L
Characterization of the high affinity heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP) and its enhancement by zinc(II).
Journal of molecular recognition : JMR 1995;8(4):247-57.
1995: Fuller S J; Storey E; Li Q X; Smith A I; Beyreuther K; Masters C L
Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein.
Biochemistry 1995;34(25):8091-8.
1995: Li Q X; Evin G; Small D H; Multhaup G; Beyreuther K; Masters C L
Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets.
The Journal of biological chemistry 1995;270(23):14140-7.
1995: Evin G; Beyreuther K; Masters C L
A synthetic substrate assay for the gamma-secretase of the beta-A4 amyloid of Alzheimer's disease.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(2):132-9.
1995: Masters C L; Beyreuther K
Molecular neuropathology of Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):410-2.
1995: Beyreuther K; Masters C L
Neurodegeneration and dementia. Alzheimer's disease as a model.
Arzneimittel-Forschung 1995;45(3A):347-50.
1995: Mönning U; Sandbrink R; Weidemann A; Banati R B; Masters C L; Beyreuther K
Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells.
The Journal of biological chemistry 1995;270(13):7104-10.
1995: Beer J; Masters C L; Beyreuther K
Cells from peripheral tissues that exhibit high APP expression are characterized by their high membrane fusion activity.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(1):51-9.
1995: Richardson E P; Masters C L
The nosology of Creutzfeldt-Jakob disease and conditions related to the accumulation of PrPCJD in the nervous system.
Brain pathology (Zurich, Switzerland) 1995;5(1):33-41.
1995: Collins S J; Masters C L
Transmissibility of Creutzfeldt-Jakob disease and related disorders.
Science progress 1995;78 ( Pt 3)():217-27.
1994: Sandbrink R; Masters C L; Beyreuther K
APP gene family: unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor.
Neurobiology of disease 1994;1(1-2):13-24.
1994: Multhaup G; Bush A I; Pollwein P; Masters C L
Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).
FEBS letters 1994;355(2):151-4.
1994: Förstl H; Czech C; Sattel H; Geiger-Kabisch C; Besthorn C; Kreger S; Mönning U; Hartmann T; Masters C; Beyreuther K
[Apolipoprotein E and Alzheimer dementia. Personal results and brief literature review]
Der Nervenarzt 1994;65(11):780-6.
1994: Sandbrink R; Masters C L; Beyreuther K
Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): two amino acids length difference to human and murine homologues.
Biochimica et biophysica acta 1994;1219(1):167-70.
1994: Bush A I; Pettingell W H; Multhaup G; d Paradis M; Vonsattel J P; Gusella J F; Beyreuther K; Masters C L; Tanzi R E
Rapid induction of Alzheimer A beta amyloid formation by zinc.
Science (New York, N.Y.) 1994;265(5177):1464-7.
1994: Beyreuther K; Masters C L
Neurobiology. Catching the culprit prion.
Nature 1994;370(6489):419-20.
1994: Li Q X; Berndt M C; Bush A I; Rumble B; Mackenzie I; Friedhuber A; Beyreuther K; Masters C L
Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet.
Blood 1994;84(1):133-42.
1994: Hesse L; Beher D; Masters C L; Multhaup G
The beta A4 amyloid precursor protein binding to copper.
FEBS letters 1994;349(1):109-16.
1994: Godec M S; Asher D M; Kozachuk W E; Masters C L; Rubi J U; Payne J A; Rubi-Villa D J; Wagner E E; Rapoport S I; Schapiro M B
Blood buffy coat from Alzheimer's disease patients and their relatives does not transmit spongiform encephalopathy to hamsters.
Neurology 1994;44(6):1111-5.
1994: Clarris H J; Nurcombe V; Small D H; Beyreuther K; Masters C L
Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.
Journal of neuroscience research 1994;38(3):248-58.
1994: Sandbrink R; Masters C L; Beyreuther K
Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.
The Journal of biological chemistry 1994;269(19):14227-34.
1994: Small D H; Nurcombe V; Reed G; Clarris H; Moir R; Beyreuther K; Masters C L
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(4):2117-27.
1994: Mönning U; Sandbrink R; Banati R B; Masters C L; Beyreuther K
Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells.
FEBS letters 1994;342(3):267-72.
1994: Masters C L; Beyreuther K
Alzheimer's disease: a clearer definition of the genetic components.
The Medical journal of Australia 1994;160(5):243-4.
1994: Sandbrink R; Masters C L; Beyreuther K
Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons.
The Journal of biological chemistry 1994;269(2):1510-7.
1994: Osuntokun B O; Ogunniyi A; Akang E E; Aghadiuno P U; Ilori A; Bamgboye E A; Beyreuther K; Masters C
Beta A4-amyloid in the brains of non-demented Nigerian Africans.
Lancet 1994;343(8888):56.
1994: Czech C; Förstl H; Hentschel F; Mönning U; Besthorn C; Geiger-Kabisch C; Sattel H; Masters C; Beyreuther K
Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change.
European archives of psychiatry and clinical neuroscience 1994;243(5):291-2.
1994: Czech C; Masters C; Beyreuther K
Alzheimer's disease and transgenic mice.
Journal of neural transmission. Supplementum 1994;44():219-30.
1993: Schubert W; Masters C L; Beyreuther K
APP+ T lymphocytes selectively sorted to endomysial tubes in polymyositis displace NCAM-expressing muscle fibers.
European journal of cell biology 1993;62(2):333-42.
1993: Hilbich C; Mönning U; Grund C; Masters C L; Beyreuther K
Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11.
The Journal of biological chemistry 1993;268(35):26571-7.
1993: Dichgans M; Mönning U; König G; Sandbrink R; Masters C L; Beyreuther K
APP expression in primary neuronal cell cultures from P6 mice during in vitro differentiation.
Dementia (Basel, Switzerland) 1993;4(6):301-7.
1993: Czech C; Mönning V; Tienari P J; Hartmann T; Masters C; Beyreuther K; Förstl H
Apolipoprotein E-epsilon 4 allele and Alzheimer's disease.
Lancet 1993;342(8882):1309.
1993: Beyreuther K; Pollwein P; Multhaup G; Mönning U; König G; Dyrks T; Schubert W; Masters C L
Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.
Annals of the New York Academy of Sciences 1993;695():91-102.
1993: Sandbrink R; Banati R; Masters C L; Beyreuther K; König G
Expression of L-APP mRNA in brain cells.
Annals of the New York Academy of Sciences 1993;695():183-9.
1993: Bush A I; Beyreuther K; Masters C L
The beta A4 amyloid protein precursor in human circulation.
Annals of the New York Academy of Sciences 1993;695():175-82.
1993: Small D H; Nurcombe V; Clarris H; Beyreuther K; Masters C L
The role of extracellular matrix in the processing of the amyloid protein precursor of Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():169-74.
1993: Bush A I; Multhaup G; Moir R D; Williamson T G; Small D H; Rumble B; Pollwein P; Beyreuther K; Masters C L
A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease.
The Journal of biological chemistry 1993;268(22):16109-12.
1993: Dyrks T; Dyrks E; Masters C L; Beyreuther K
Amyloidogenicity of rodent and human beta A4 sequences.
FEBS letters 1993;324(2):231-6.
1993: Multhaup G; Masters C L; Beyreuther K
A molecular approach to Alzheimer's disease.
Biological chemistry Hoppe-Seyler 1993;374(1):1-8.
1993: Gearing M; Wilson R W; Unger E R; Shelton E R; Chan H W; Masters C L; Beyreuther K; Mirra S S
Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study.
Journal of neuropathology and experimental neurology 1993;52(1):22-30.
1992: Hilbich C; Kisters-Woike B; Reed J; Masters C L; Beyreuther K
Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides.
Journal of molecular biology 1992;228(2):460-73.
1992: Mönning U; König G; Banati R B; Mechler H; Czech C; Gehrmann J; Schreiter-Gasser U; Masters C L; Beyreuther K
Alzheimer beta A4-amyloid protein precursor in immunocompetent cells.
The Journal of biological chemistry 1992;267(33):23950-6.
1992: Small D H; Nurcombe V; Moir R; Michaelson S; Monard D; Beyreuther K; Masters C L
Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(11):4143-50.
1992: Moir R D; Martins R N; Bush A I; Small D H; Milward E A; Rumble B A; Multhaup G; Beyreuther K; Masters C L
Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization.
Journal of neurochemistry 1992;59(4):1490-8.
1992: Dyrks T; Dyrks E; Hartmann T; Masters C; Beyreuther K
Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.
The Journal of biological chemistry 1992;267(25):18210-7.
1992: Dyrks T; Dyrks E; Masters C; Beyreuther K
Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate.
FEBS letters 1992;309(1):20-4.
1992: Milward E A; Papadopoulos R; Fuller S J; Moir R D; Small D; Beyreuther K; Masters C L
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.
Neuron 1992;9(1):129-37.
1992: König G; Mönning U; Czech C; Prior R; Banati R; Schreiter-Gasser U; Bauer J; Masters C L; Beyreuther K
Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.
The Journal of biological chemistry 1992;267(15):10804-9.
1992: Pollwein P; Masters C L; Beyreuther K
The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.
Nucleic acids research 1992;20(1):63-8.
1992: Beyreuther K; Dyrks T; Hilbich C; Mönning U; König G; Multhaup G; Pollwein P; Masters C L
Amyloid precursor protein (APP) and beta A4 amyloid in Alzheimer's disease and Down syndrome.
Progress in clinical and biological research 1992;379():159-82.
1992: Bush A I; Beyreuther K; Masters C L
Beta A4 amyloid protein and its precursor in Alzheimer's disease.
Pharmacology & therapeutics 1992;56(1):97-117.
1991: Schubert W; Prior R; Weidemann A; Dircksen H; Multhaup G; Masters C L; Beyreuther K
Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.
Brain research 1991;563(1-2):184-94.
1991: Hilbich C; Kisters-Woike B; Reed J; Masters C L; Beyreuther K
Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.
European journal of biochemistry / FEBS 1991;201(1):61-9.
1991: Godec M S; Asher D M; Masters C L; Kozachuk W E; Friedland R P; Gibbs C J; Gajdusek D C; Rapoport S I; Schapiro M B
Evidence against the transmissibility of Alzheimer's disease.
Neurology 1991;41(8):1320.
1991: Beyreuther K; Masters C L
Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function.
Brain pathology (Zurich, Switzerland) 1991;1(4):241-51.
1991: Masters C L; Beyreuther K
Alzheimer's disease: molecular basis of structural lesions.
Brain pathology (Zurich, Switzerland) 1991;1(4):226-7.
1991: Bauer J; König G; Strauss S; Jonas U; Ganter U; Weidemann A; Mönning U; Masters C L; Volk B; Berger M
In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells.
FEBS letters 1991;282(2):335-40.
1991: Matkovic Z; Davis S; Gonzales M; Kalnins R; Masters C L
Surgical risk of hemorrhage in cerebral amyloid angiopathy.
Stroke; a journal of cerebral circulation 1991;22(4):456-61.
1991: Le Coz P; Mikol J; Ferrand J; Woimant F; Masters C; Beyreuther K; Haguenau M; Cophignon J; Pepin B
Granulomatous angiitis and cerebral amyloid angiopathy presenting as a mass lesion.
Neuropathology and applied neurobiology 1991;17(2):149-55.
1991: Hilbich C; Kisters-Woike B; Reed J; Masters C L; Beyreuther K
Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.
Journal of molecular biology 1991;218(1):149-63.
1991: Prior R; Mönning U; Schreiter-Gasser U; Weidemann A; Blennow K; Gottfries C G; Masters C L; Beyreuther K
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Neuroscience letters 1991;124(1):69-73.
1991: Martin L J; Sisodia S S; Koo E H; Cork L C; Dellovade T L; Weidemann A; Beyreuther K; Masters C; Price D L
Amyloid precursor protein in aged nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1461-5.
1991: Richards S J; Waters J J; Beyreuther K; Masters C L; Wischik C M; Sparkman D R; White C L; Abraham C R; Dunnett S B
Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology.
The EMBO journal 1991;10(2):297-303.
1991: König G; Salbaum J M; Wiestler O; Lang W; Schmitt H P; Masters C L; Beyreuther K
Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients.
Brain research. Molecular brain research 1991;9(3):259-62.
1991: Martin J J; Gheuens J; Bruyland M; Cras P; Vandenberghe A; Masters C L; Beyreuther K; Dom R; Ceuterick C; Lübke U
Early-onset Alzheimer's disease in 2 large Belgian families.
Neurology 1991;41(1):62-8.
1991: Martins R N; Robinson P J; Chleboun J O; Beyreuther K; Masters C L
The molecular pathology of amyloid deposition in Alzheimer's disease.
Molecular neurobiology 1991;5(2-4):389-98.
1990: Mönning U; König G; Prior R; Mechler H; Schreiter-Gasser U; Masters C L; Beyreuther K
Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes.
FEBS letters 1990;277(1-2):261-6.
1990: Cork L C; Masters C; Beyreuther K; Price D L
Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits.
The American journal of pathology 1990;137(6):1383-92.
1990: Sorimachi K; Craik D J; Lloyd E J; Beyreuther K; Masters C L
Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein.
Biochemistry international 1990;22(3):447-54.
1990: König G; Masters C L; Beyreuther K
Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern.
FEBS letters 1990;269(2):305-10.
1990: Delaère P; Duyckaerts C; Masters C; Beyreuther K; Piette F; Hauw J J
Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person.
Neuroscience letters 1990;116(1-2):87-93.
1990: Masters C
About a peculiar disease. Interview by Gay Hudson.
The Australian nurses' journal 1990;20(1):12-4.
1990: Catteruccia N; Willingale-Theune J; Bunke D; Prior R; Masters C L; Crisanti A; Beyreuther K
Ultrastructural localization of the putative precursors of the A4 amyloid protein associated with Alzheimer's disease.
The American journal of pathology 1990;137(1):19-26.
1990: Irving W L; Crimmins D S; Masters C L; Cunningham A L
Creutzfeldt-Jakob disease and slow infections: a review.
Australian and New Zealand journal of medicine 1990;20(3):283-90.
1990: Dropulic B; Masters C L
Entry of neurotropic arboviruses into the central nervous system: an in vitro study using mouse brain endothelium.
The Journal of infectious diseases 1990;161(4):685-91.
1990: Koo E H; Sisodia S S; Archer D R; Martin L J; Weidemann A; Beyreuther K; Fischer P; Masters C L; Price D L
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1561-5.
1990: Beyreuther K; Masters C L
Nomenclature of amyloid A4 proteins and their precursors in Alzheimer's disease and Down's syndrome.
Neurobiology of aging 1990;11(1):66-8.
1990: Walker L C; Masters C; Beyreuther K; Price D L
Amyloid in the brains of aged squirrel monkeys.
Acta neuropathologica 1990;80(4):381-7.
1990: Richards S J; Waters J J; Rogers D C; Martel F L; Sparkman D R; White C L; Beyreuther K; Masters C L; Dunnett S B
Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology.
Progress in brain research 1990;82():215-23.
1990: Masters C L; Beyreuther K
Protein abnormalities in neurofibrillary tangles: their relation to the extracellular amyloid deposits of the A4 protein in Alzheimer's disease.
Advances in neurology 1990;51():151-61.
1989: Rozemuller J M; Eikelenboom P; Stam F C; Beyreuther K; Masters C L
A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition.
Journal of neuropathology and experimental neurology 1989;48(6):674-91.
1989: Ghetti B; Tagliavini F; Masters C L; Beyreuther K; Giaccone G; Verga L; Farlow M R; Conneally P M; Dlouhy S R; Azzarelli B
Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family.
Neurology 1989;39(11):1453-61.
1989: Hyman B T; Van Hoesen G W; Beyreuther K; Masters C L
A4 amyloid protein immunoreactivity is present in Alzheimer's disease neurofibrillary tangles.
Neuroscience letters 1989;101(3):352-5.
1989: Mann D M; Brown A; Prinja D; Davies C A; Landon M; Masters C L; Beyreuthers K
An analysis of the morphology of senile plaques in Down's syndrome patients of different ages using immunocytochemical and lectin histochemical techniques.
Neuropathology and applied neurobiology 1989;15(4):317-29.
1989: Nochlin D; Sumi S M; Bird T D; Snow A D; Leventhal C M; Beyreuther K; Masters C L
Familial dementia with PrP-positive amyloid plaques: a variant of Gerstmann-Sträussler syndrome.
Neurology 1989;39(7):910-8.
1989: Rumble B; Retallack R; Hilbich C; Simms G; Multhaup G; Martins R; Hockey A; Montgomery P; Beyreuther K; Masters C L
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.
The New England journal of medicine 1989;320(22):1446-52.
1989: Weidemann A; König G; Bunke D; Fischer P; Salbaum J M; Masters C L; Beyreuther K
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.
Cell 1989;57(1):115-26.
1989: Mastaglia F L; Masters C L; Beyreuther K; Kakulas B A
Deposition of Alzheimer's disease amyloid (A4) protein in the cerebral cortex in Parkinson's disease.
Progress in clinical and biological research 1989;317():475-84.
1989: Salbaum J M; Weidemann A; Masters C L; Beyreuther K
The promoter of Alzheimer's disease amyloid A4 precursor gene.
Progress in clinical and biological research 1989;317():277-83.
1989: Masters C L
Creutzfeldt-Jakob disease: its origins.
Alzheimer disease and associated disorders 1989;3(1-2):46-51.
1989: Dyrks T; König G; Hilbich C; Masters C L; Beyreuther K
Molecular pathology of the amyloid A4 precursor of Alzheimer's disease.
Progress in clinical and biological research 1989;317():877-91.
1989: König G; Beyreuther K; Masters C L; Schmitt H P; Salbaum J M
PreA4 mRNA distribution in brain areas.
Progress in clinical and biological research 1989;317():1027-36.
1989: Masters C L; Beyreuther K T
The pathology of the amyloid A4 precursor of Alzheimer's disease.
Annals of medicine 1989;21(2):89-90.
1988: Davies L; Wolska B; Hilbich C; Multhaup G; Martins R; Simms G; Beyreuther K; Masters C L
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques.
Neurology 1988;38(11):1688-93.
1988: Salbaum J M; Weidemann A; Lemaire H G; Masters C L; Beyreuther K
The promoter of Alzheimer's disease amyloid A4 precursor gene.
The EMBO journal 1988;7(9):2807-13.
1988: Dyrks T; Weidemann A; Multhaup G; Salbaum J M; Lemaire H G; Kang J; Müller-Hill B; Masters C L; Beyreuther K
Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease.
The EMBO journal 1988;7(4):949-57.
1988: Papadimitriou J M; Hockey A; Tan N; Masters C L
Rett syndrome: abnormal membrane-bound lamellated inclusions in neurons and oligodendroglia.
American journal of medical genetics 1988;29(2):365-8.
1988: Zimmermann K; Herget T; Salbaum J M; Schubert W; Hilbich C; Cramer M; Masters C L; Multhaup G; Kang J; Lemaire H G
Localization of the putative precursor of Alzheimer's disease-specific amyloid at nuclear envelopes of adult human muscle.
The EMBO journal 1988;7(2):367-72.
1988: Masters C L; Beyreuther K
The blood-brain barrier in Alzheimer's disease and normal aging.
Neurobiology of aging 1988;9(1):43-4.
1988: Masters C L; Beyreuther K
Neuropathology of unconventional virus infections: molecular pathology of spongiform change and amyloid plaque deposition.
Ciba Foundation symposium 1988;135():24-36.
1987: Dropulic B; Masters C L
Culture of mouse brain capillary endothelial cell lines that express factor VIII, gamma-glutamyl transpeptidase, and form junctional complexes in vitro.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1987;23(11):775-81.
1987: Guiroy D C; Miyazaki M; Multhaup G; Fischer P; Garruto R M; Beyreuther K; Masters C L; Simms G; Gibbs C J; Gajdusek D C
Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(7):2073-7.
1987: Kang J; Lemaire H G; Unterbeck A; Salbaum J M; Masters C L; Grzeschik K H; Multhaup G; Beyreuther K; Müller-Hill B
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
Nature 1987;325(6106):733-6.
1987: Masters C L; Beyreuther K
Neuronal origin of cerebral amyloidogenic proteins: their role in Alzheimer's disease and unconventional virus diseases of the nervous system.
Ciba Foundation symposium 1987;126():49-64.
1986: Masters C L; Beyreuther K
The structure of amyloid filaments in Alzheimer's disease and the unconventional virus infections of the nervous system.
Psychological medicine 1986;16(4):735-7.
1986: Martins R N; Stokes G B; Masters C L
Regulation of liver and brain hexose monophosphate dehydrogenases by insulin and dietary intake in the female rat.
Molecular and cellular biochemistry 1986;70(2):169-75.
1986: Martins R N; Harper C G; Stokes G B; Masters C L
Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress.
Journal of neurochemistry 1986;46(4):1042-5.
1986: Tan N; Kakulas B A; Masters C L; Gajdusek D C; Garruto R M; Chen K M; Gibbs C J
Observations on the clinical presentations and the neuropathological findings of amyotrophic lateral sclerosis in Australia and Guam.
Annals of the Academy of Medicine, Singapore 1986;15(1):62-6.
1986: Harper C G; Day T J; Masters C L
Rapidly progressive dementia with ataxia.
The Medical journal of Australia 1986;144(1):24-6, 28.
1985: Masters C L; Multhaup G; Simms G; Pottgiesser J; Martins R N; Beyreuther K
Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.
The EMBO journal 1985;4(11):2757-63.
1985: Masters C L; Simms G; Weinman N A; Multhaup G; McDonald B L; Beyreuther K
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4245-9.
1985: Masters C L; Jacobsen P; Kakulas B A
Decontamination of formaldehyde-fixed cerebral tissues of Creutzfeldt-Jakob disease by autoclaving, without the loss of microscopic visual quality.
Journal of neuropathology and experimental neurology 1985;44(3):304-6.
1985: Masters C L; McDonald B L; Lagenauer C; Schachner M; Franko M C
Loop arrays in mouse brain demonstrated with antisera to cytokeratins and monoclonal antibodies to several classes of intermediate filaments: strain differences and developmental expression.
Brain research 1985;334(2):267-79.
1985: Masters C
Perspectives on prions.
Nature 1985;314(6006):15-6.
1984: Masters C L
Etiology and pathogenesis of Alzheimer's disease.
Pathology 1984;16(3):233-4.
1984: Masters C L; Rohwer R G; Franko M C; Brown P; Gajdusek D C
The sequential development of spongiform change and gliosis of scrapie in the golden Syrian hamster.
Journal of neuropathology and experimental neurology 1984;43(3):242-52.
1983: Salazar A M; Masters C L; Gajdusek D C; Gibbs C J
Syndromes of amyotrophic lateral sclerosis and dementia: relation to transmissible Creutzfeldt-Jakob disease.
Annals of neurology 1983;14(1):17-26.
1983: Scrimgeour E M; Masters C L; Alpers M P; Kaven J; Gajusek D C
A clinico-pathological study of a case of kuru.
Journal of the neurological sciences 1983;59(2):265-75.
1983: Schachner M; Sommer I; Lagenaur C; Masters C
Glial antigens C1 and M1 in normal and abnormal development and after injury.
Birth defects original article series 1983;19(4):315-25.
1983: Merz P A; Wisniewski H M; Somerville R A; Bobin S A; Masters C L; Iqbal K
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques.
Acta neuropathologica 1983;60(1-2):113-24.
1983: Asher D M; Masters C L; Gajdusek D C; Gibbs C J
Familial spongiform encephalopathies.
Research publications - Association for Research in Nervous and Mental Disease 1983;60():273-91.
1982: Moreau-Dubois M C; Brown P; Rohwer R G; Masters C L; Franko M; Gajdusek D C
Experimental scrapie in golden Syrian hamsters: temporal comparison of in vitro cell-fusing activity with brain infectivity and histopathological changes.
Infection and immunity 1982;37(1):195-9.
1982: Nyberg P; Almay B G; Carlsson A; Masters C; Winblad B
Brain monoamine abnormalities in the two types of Creutzfeldt-Jakob disease.
Acta neurologica Scandinavica 1982;66(1):16-24.
1982: Lagenaur C; Masters C; Schachner M
Changes in expression of glial antigens M1 and C1 after cerebellar injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(4):470-6.
1981: Franko M C; Masters C L; Gibbs C J; Gajdusek D C
Monoclonal antibodies to central nervous system antigens.
Journal of neuroimmunology 1981;1(4):391-411.
1981: Monreal J; Collins G H; Masters C L; Fisher C M; Kim R C; Gibbs C J; Gajdusek D C
Creutzfeldt-Jakob disease in an adolescent.
Journal of the neurological sciences 1981;52(2-3):341-50.
1981: Masters C L; Gajdusek D C; Gibbs C J
The familial occurrence of Creutzfeldt-Jakob disease and Alzheimer's disease.
Brain : a journal of neurology 1981;104(3):535-58.
1981: Masters C L; Gajdusek D C; Gibbs C J
Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies.
Brain : a journal of neurology 1981;104(3):559-88.
1981: Schoene W C; Masters C L; Gibbs C J; Gajdusek D C; Tyler H R; Moore F D; Dammin G J
Transmissible spongiform encephalopathy (Creutzfeldt-Jakob disease). Atypical clinical and pathological findings.
Archives of neurology 1981;38(8):473-7.
1981: Landis D M; Williams R S; Masters C L
Golgi and electronmicroscopic studies of spongiform encephalopathy.
Neurology 1981;31(5):538-49.
1981: Tan N T; Kakulas B A; Masters C L; Chen K M; Gibbs C J; Gajdusek D C
Neuropathology of the cortical lesions of the Parkinsonian-dementia (PD) complex of Guam.
Clinical and experimental neurology 1981;17():227-34.
1980: Goudsmit J; Morrow C H; Asher D M; Yanagihara R T; Masters C L; Gibbs C J; Gajdusek D C
Evidence for and against the transmissibility of Alzheimer disease.
Neurology 1980;30(9):945-50.
1980: Gibbs C J; Amyx H L; Bacote A; Masters C L; Gajdusek D C
Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates.
The Journal of infectious diseases 1980;142(2):205-8.
1980: Gálvez S; Gajdusek D C; Masters C L
[Experimental transmission of Creutzfeldt-Jakob disease to the guinea pig (author's transl)]
Revista médica de Chile 1980;108(4):299-303.
1980: Baringer J R; Gajdusek D C; Gibbs C J; Masters C L; Stern W E; Terry R D
Transmissible dementias: current problems in tissue handling.
Neurology 1980;30(3):302-3.
1980: Galvez S; Masters C; Gajdusek C
Descriptive epidemiology of Creutzfeldt-Jakob disease in Chile.
Archives of neurology 1980;37(1):11-4.
1979: Masters C L; Harris J O; Gajdusek D C; Gibbs C J; Bernoulli C; Asher D M
Creutzfeldt-Jakob disease: patterns of worldwide occurrence and the significance of familial and sporadic clustering.
Annals of neurology 1979;5(2):177-88.
1978: Masters C L; Richardson E P
Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change.
Brain : a journal of neurology 1978;101(2):333-44.
1978: Masters C L
Pathogenesis of the Arnold-Chiari malformation: the significance of hydrocephalus and aqueduct stenosis.
Journal of neuropathology and experimental neurology 1978;37(1):56-74.
1977: Hockey A; Masters C L
Menkes' kinky (steely) hair disease.
The Australasian journal of dermatology 1977;18(2):77-80.
1976: Masters C L; Kakulas B A; Alpers M P; Gajdusek D C; Gibbs C J
Preclinical lesions and their progression in the experimental spongiform encephalopathies (kuru and Creutzfeldt-Jakob disease) in primates.
Journal of neuropathology and experimental neurology 1976;35(6):593-605.
1976: Masters C L; Alpers M P; Gajdusek D C; Gibbs C J; Kakulas B A
Experimental kuru in the gibbon and sooty mangabey and Creutzfeldt-Jakob disease in the pigtailed macaque. With a summary of the host range of the subacute spongiform virus encephalopathies.
Journal of medical primatology 1976;5(4):205-9.

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