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Colin Masters

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Yen Ying Lim; Ralph N Martins; Colin L Masters; Christopher C Rowe; Albrecht Stöffler; Cassandra E I Szoeke; Victor L Villemagne; David Ames; Tim Ashwood; Ashley Bush; David Darby; Kathryn A Ellis; Karra Harrington; Judith Jaeger; Rebecca Lachovitzki; Paul Maruff
Three-Month Stability of the CogState Brief Battery in Healthy Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease: Results from the Australian Imaging, Biomarkers, and Lifestyle-Rate of Change Substudy (AIBL-ROCS).
Vijaya Kenche; Colin L Masters; Izabela Zawisza; Wojciech Bal; Kevin J Barnham; Simon C Drew
Mixed Ligand Cu(2+) Complexes of a Model Therapeutic with Alzheimer's Amyloid-β Peptide and Monoamine Neurotransmitters.
Victor L Villemagne; David Ames; Pierrick Bourgeat; Belinda Brown; Samantha Burnham; Kathryn A Ellis; S Lance Macaulay; Ralph Martins; Paul Maruff; Colin L Masters; Christopher C Rowe; Olivier Salvado; Cassandra E I Szoeke
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.

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2013: Yen Ying Lim; Ralph N Martins; Colin L Masters; Christopher C Rowe; Albrecht Stöffler; Cassandra E I Szoeke; Victor L Villemagne; David Ames; Tim Ashwood; Ashley Bush; David Darby; Kathryn A Ellis; Karra Harrington; Judith Jaeger; Rebecca Lachovitzki; Paul Maruff
Three-Month Stability of the CogState Brief Battery in Healthy Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease: Results from the Australian Imaging, Biomarkers, and Lifestyle-Rate of Change Substudy (AIBL-ROCS).
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2013;28(4):320-30.
2013: Vijaya Kenche; Colin L Masters; Izabela Zawisza; Wojciech Bal; Kevin J Barnham; Simon C Drew
Mixed Ligand Cu(2+) Complexes of a Model Therapeutic with Alzheimer's Amyloid-β Peptide and Monoamine Neurotransmitters.
Inorganic chemistry 2013;52(8):4303-18.
2013: Victor L Villemagne; David Ames; Pierrick Bourgeat; Belinda Brown; Samantha Burnham; Kathryn A Ellis; S Lance Macaulay; Ralph Martins; Paul Maruff; Colin L Masters; Christopher C Rowe; Olivier Salvado; Cassandra E I Szoeke
Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study.
Lancet neurology 2013;12(4):357-67.
2013: Andrew D Watt; Michelle Fodero-Tavoletti; Lin Wai Hung; Craig A Hutton; Timothy Johanssen; Woan Mei Kok; Colin L Masters; Catriona A McLean; Keyla A Perez; Alan Rembach; Nicki A Sherrat; Victor L Villemagne; Kevin J Barnham
Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples.
Acta neuropathologica 2013;125(4):549-64.
2013: Vijaya Kenche; Jeffrey Kwok; Varsha Lal; Colin L Masters; Kazuma Murakami; Keyla Perez; Nikki Sherratt; Irene Volitakes; Roberto Cappai; Giuseppe D Ciccotosto; Mikhalina Cortes; Nicole Critch; Lin W Hung; Paul A Adlard; Kevin J Barnham
Development of a platinum complex as an anti-amyloid agent for the therapy of Alzheimer's disease.
Angewandte Chemie (International ed. in English) 2013;52(12):3374-8.
2013: Timothy M Ryan; Victor A Streltsov; Lynne J Waddington; Kerry Breheney; Joanne Caine; Cyril Curtain; Nigel Kirby; Colin L Masters; Haydyn D T Mertens; Julie Nigro; Blaine R Roberts
Ammonium hydroxide treatment of Aβ produces an aggregate free solution suitable for biophysical and cell culture characterization.
PeerJ 2013;1():e73.
2013: S Frost; Yogesan Kanagasingam; Ralph N Martins; Colin L Masters; S Rainey-Smith; Christopher C Rowe; O Salvado; H Sohrabi; Cassandra E I Szoeke; J Vignarajan; Victor L Villemagne; S Lance Macaulay; David Ames; Pierrick Bourgeat; Kathryn A Ellis
Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease.
Translational psychiatry 2013;3():e233.
2013: Kathryn A Ellis; Karra Harrington; Yen Ying Lim; Ralph N Martins; Paul Maruff; Colin L Masters; Christopher C Rowe; Greg Savage; Cassandra E I Szoeke; Victor L Villemagne; David Ames; Ashley I Bush; David Darby
Decline in cognitive function over 18 months in healthy older adults with high amyloid-β.
Journal of Alzheimer's disease : JAD 2013;34(4):861-71.
2013: Alan Rembach; Blaine R Roberts; Christopher C Rowe; Rebecca L Rumble; Brett O Trounson; Victor L Villemagne; Irene Volitakis; Andrew D Watt; William Wilson; James D Doecke; Kathryn A Ellis; Noel G Faux; Christopher J Fowler; Ralph N Martins; Colin L Masters; Kelly K Pertile; David Ames; Ashley I Bush
Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2013;34(1):171-82.
2013: Yen Ying Lim; Ralph N Martins; David Ames; Ashley I Bush; David Darby; Kathryn A Ellis; Joanne Gale; Karra Harrington; Colin L Masters; Robert H Pietrzak; Christopher C Rowe; Greg Savage; Cassandra E I Szoeke; Victor L Villemagne; Paul Maruff
Cognitive decline in adults with amnestic mild cognitive impairment and high amyloid-β: prodromal Alzheimer's disease?
Journal of Alzheimer's disease : JAD 2013;33(4):1167-76.
2013: Yen Ying Lim; Ralph N Martins; David Ames; Tim Ashwood; Ashley I Bush; David Darby; Kathryn A Ellis; Karra Harrington; Judith Jaeger; Colin L Masters; Robert H Pietrzak; Christopher C Rowe; Cassandra E I Szoeke; Victor L Villemagne; Paul Maruff
Rapid decline in episodic memory in healthy older adults with high amyloid-β.
Journal of Alzheimer's disease : JAD 2013;33(3):675-9.
2012: Yen Ying Lim; Ralph N Martins; Paul Maruff; Colin L Masters; Robert H Pietrzak; Christopher C Rowe; Greg Savage; Cassandra E I Szoeke; Victor L Villemagne; David Ames; David Darby; Kathryn A Ellis; Karra Harrington
Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults.
Neurology 2012;79(16):1645-52.
2012: James D Doecke; Kathryn A Ellis; Noel G Faux; Christopher Fowler; Veer B Gupta; Richard Head; Chiou-Peng Lam; Simon M Laws; S Lance Macaulay; Ralph N Martins; Colin L Masters; Alinda Mondal; Kelly Pertile; Alan Rembach; Mark Rodrigues; Christopher C Rowe; Rebecca Rumble; Cassandra Szoeke; Kevin Taddei; Tania Taddei; Brett Trounson; William Wilson; David Ames; Justin Bedo; Belinda Brown; Samantha C Burnham; Ashley I Bush; Karl De Ruyck
Blood-based protein biomarkers for diagnosis of Alzheimer disease.
Archives of neurology 2012;69(10):1318-25.
2012: Michelle T Fodero-Tavoletti; Sabine Krause; Lucas Martin; Colin L Masters; Catriona A McLean; Christopher C Rowe; Andrea Thiele; Victor L Villemagne; Mathias Berndt; Damian Brockschnieder; Andrea R Connor; Ludger M Dinkelborg; Thomas Dyrks; Roberto Cappai
In vitro characterization of [18F]-florbetaben, an Aβ imaging radiotracer.
Nuclear medicine and biology 2012;39(7):1042-8.
2012: Frances Corrigan; Colin L Masters; Peter C Blumbergs; Roberto Cappai; Robert Vink; Corinna van den Heuvel
sAPPα rescues deficits in amyloid precursor protein knockout mice following focal traumatic brain injury.
Journal of neurochemistry 2012;122(1):208-20.
2012: Genevieve M Klug; Colin L Masters; Amelia McGlade; Marion Simpson; Christiane Stehmann; Alison Boyd; Steven J Collins
Surveillance of Creutzfeldt-Jakob disease in Australia: update to December 2011.
Communicable diseases intelligence quarterly report 2012;36(2):E174-9.
2012: Colin L Masters; Dennis J Selkoe
Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease.
Cold Spring Harbor perspectives in medicine 2012;2(6):a006262.
2012: Victor L Villemagne; Kenneth Young; Henri Tochon-Danguy; J Gordon Chan; Gareth Jones; Colin L Masters; Rachel S Mulligan; Graeme O'Keefe; Kevin Ong; Svetlana Pejoska; Christopher C Rowe
Comparison of 11C-PiB and 18F-florbetaben for Aβ imaging in ageing and Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2012;39(6):983-9.
2012: Frances Corrigan; Colin L Masters; Peter C Blumbergs; Roberto Cappai; Robert Vink; Corinna van den Heuvel
Characterisation of the effect of knockout of the amyloid precursor protein on outcome following mild traumatic brain injury.
Brain research 2012;1451():87-99.
2012: Frances Corrigan; Colin L Masters; Peter C Blumbergs; Roberto Cappai; Robert Vink; Corinna van den Heuvel
Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice.
Neuroscience letters 2012;515(1):50-4.
2012: Lin W Hung; Su Ling Leong; SinChun Lim; Xiang Liu; Colin L Masters; Graeme O'Keefe; Chi L L Pham; Andrew K Powell; Blaine R Roberts; David M Shackleford; Nicki A Sherratt; Victor L Villemagne; Anthony R White; Simon Wilkins; Ashley I Bush; Roberto Cappai; Lesley Cheng; Robert A Cherny; Francis C K Chiu; Peter J Crouch; Janetta G Culvenor; Paul S Donnelly; David Finkelstein; Jessica George; Andrew F Hill; Scott Ayton; Kevin J Barnham
The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
The Journal of experimental medicine 2012;209(4):837-54.
2012: Oscar Acosta; David Ames; Vincent Barra; Erik Bonner; Pierrick Bourgeat; Gaël Chételat; Vincent Doré; Kathryn A Ellis; Jean-Marie Favreau; Jurgen Fripp; Florence Gris; Ralph N Martins; Colin L Masters; Parnesh Raniga; Christopher C Rowe; Andrea Rueda; Cassandra Szoeke; Victor L Villemagne; Di Xiao; Olivier Salvado
Cortical surface mapping using topology correction, partial flattening and 3D shape context-based non-rigid registration for use in quantifying atrophy in Alzheimer's disease.
Journal of neuroscience methods 2012;205(1):96-109.
2012: Victor L Villemagne; Michael W Weiner; David J Brooks; Bradley T Hyman; Milos D Ikonomovic; Kenji Ishii; Clifford R Jack; William J Jagust; Keith A Johnson; William E Klunk; Robert A Koeppe; Val J Lowe; Colin L Masters; Chester A Mathis; Thomas J Montine; John C Morris; Agneta Nordberg; Ronald C Petersen; Eric M Reiman; Christopher C Rowe; Dennis J Selkoe; Reisa A Sperling; Koen Van Laere; Alexander Drzezga
Aβ Imaging: feasible, pertinent, and vital to progress in Alzheimer's disease.
European journal of nuclear medicine and molecular imaging 2012;39(2):209-19.
2012: Gawain McColl; Tara L Pukala; Blaine R Roberts; Christine M Roberts; Timothy M Ryan; Kevin J Barnham; Ashley I Bush; Vijaya Kenche; Christopher D Link; Colin L Masters; Robert A Cherny
Utility of an improved model of amyloid-beta (Aβ₁₋₄₂) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease.
Molecular neurodegeneration 2012;7():57.
2012: B M Brown; S Burnham; Kathryn A Ellis; V B Gupta; Ralph N Martins; Colin L Masters; A Mondal; J J Peiffer; S R Rainey-Smith; Christopher C Rowe; H R Sohrabi; Cassandra E I Szoeke; Kevin Taddei; D Ames
Intense physical activity is associated with cognitive performance in the elderly.
Translational psychiatry 2012;2():e191.
2012: Elizabeth V Cyarto; Patricia M Desmond; Kathryn A Ellis; Nicola T Lautenschlager; Ralph N Martins; Colin L Masters; Pramit M Phal; Christopher C Rowe; Olivier Salvado; Matthew J Sharman; Cassandra E I Szoeke; David Ames; Kay L Cox
Protocol for a randomized controlled trial evaluating the effect of physical activity on delaying the progression of white matter changes on MRI in older adults with memory complaints and mild cognitive impairment: the AIBL Active trial.
BMC psychiatry 2012;12():167.
2012: S Gardener; Y Gu; R Head; J B Keogh; S L Macaulay; Ralph N Martins; Colin L Masters; S L Mathieson; A Mondal; S R Rainey-Smith; Christopher C Rowe; N Scarmeas; Cassandra E I Szoeke; Kevin Taddei; V K Ward; D Ames; M Barnes; P M Clifton; Kathryn A Ellis
Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population.
Translational psychiatry 2012;2():e164.
2012: Victoria Lewis; Colin L Masters; Cathryn L Haigh; Andrew F Hill; Victoria A Lawson; Steven J Collins
Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity.
Molecular neurodegeneration 2012;7():18.
2012: Andrew D Watt; Colin L Masters; Keyla Perez; Alan R Rembach; Victor L Villemagne; Kevin J Barnham
Variability in blood-based amyloid-beta assays: the need for consensus on pre-analytical processing.
Journal of Alzheimer's disease : JAD 2012;30(2):323-36.
2012: Gaël Chételat; Kathryn A Ellis; Colin L Masters; Kerryn E Pike; Christopher C Rowe; Victor L Villemagne; David Ames
Relationship between memory performance and β-amyloid deposition at different stages of Alzheimer's disease.
Neuro-degenerative diseases 2012;10(1-4):141-4.
2012: Victor L Villemagne; Daniel M Skovronsky; Gaël Chételat; John Drago; Gareth Jones; Hank F Kung; Colin L Masters; Rachel S Mulligan; Nobuyuki Okamura; Graeme O'Keefe; Svetlana Pejoska; Michael Pontecorvo; Christopher C Rowe
Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging.
Neuro-degenerative diseases 2012;10(1-4):161-5.
2012: Yen Ying Lim; Ralph N Martins; Paul Maruff; Colin L Masters; Christopher C Rowe; Greg Savage; Cassandra E I Szoeke; David Ames; David Darby; Kathryn A Ellis; Karra Harrington
Use of the CogState Brief Battery in the assessment of Alzheimer's disease related cognitive impairment in the Australian Imaging, Biomarkers and Lifestyle (AIBL) study.
Journal of clinical and experimental neuropsychology 2012;34(4):345-58.
2011: Victoria A Lawson; Colin L Masters; Jeremy M Welton; Roberto Cappai; Peter J Crouch; Helen M Klemm; Giuseppe D Ciccotosto
Gene knockout of tau expression does not contribute to the pathogenesis of prion disease.
Journal of neuropathology and experimental neurology 2011;70(11):1036-45.
2011: Peter J Crouch; Paul S Donnelly; Mark A Greenough; Lin W Hung; Colin L Masters; Alexandra I Mot; Sarah J Parker; Maria S Savva; Irene Volitakis; Paul A Adlard; Kevin J Barnham; Ashley I Bush; Robert A Cherny; Anthony R White
The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity.
Journal of neurochemistry 2011;119(1):220-30.
2011: Michelle T Fodero-Tavoletti; Colin L Masters; Christopher C Rowe; Victor L Villemagne; Kevin J Barnham; Roberto Cappai
Amyloid-β: the seeds of darkness.
The international journal of biochemistry & cell biology 2011;43(9):1247-51.
2011: Victor L Villemagne; Henri Tochon-Danguy; Uwe Ackerman; J Gordon Chan; Lueder Fels; Gerhard Holl; Gareth Jones; Colin L Masters; Rachel S Mulligan; Graeme O'Keefe; Kevin Ong; Svetlana Pejoska; Barbara Putz; Cornelia B Reininger; Beate Rohde; Christopher C Rowe
Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(8):1210-7.
2011: Cathryn L Haigh; Victoria A Lawson; Victoria Lewis; Colin L Masters; Amelia R McGlade; Steven J Collins
Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro.
Free radical biology & medicine 2011;51(3):594-608.
2011: P A Yates; S Farquharson; Colin L Masters; Christopher C Rowe; R Sirisriro; Victor L Villemagne
Cerebral microhemorrhage and brain β-amyloid in aging and Alzheimer disease.
Neurology 2011;77(1):48-54.
2011: Niklas Mattsson; John McAuliffe; Marc Mercken; Abhay Moghekar; José Luis Molinuevo; Thomas J Montine; William Nowatzke; Richard J O'Brien; Markus Otto; George P Paraskevas; Lucilla Parnetti; Staffan Persson; Ronald C. Petersen; David Prvulovic; Robert A Rissman; Elio Scarpini; Johannes Schröder; Leslie M Shaw; Anders Skinningsrud; Brith Skrogstad; Hilkka Soininen; Annette Spreer; Alessandro Stefani; Leda Talib; Charlotte Teunissen; John Q Trojanowski; Hayrettin Tumani; Robert M Umek; Bianca Van Broeck; hugo Marcel vanderstichele; Laszlo Vecsei; Marcel M Verbeek; Manfred Windisch; Henrik Zetterberg; Jing Zhang; Luisella Bocchio-Chiavetto; Maria C Carrillo; Sonia Chalbot; Davide Chiasserini; Els Coart; Neal Cutler; Gunilla Dahlfors; Herman P M de Reus; Stefan Duller; Anne M Fagan; Orestes Forlenza; Giovanni B Frisoni; Douglas Galasko; Daniela Galimberti; Harald Hampel; Aase Handberg; Michael T Heneka; Adrianna Z Herskovits; Sanna-Kaisa Herukka; David M Holtzman; Christian Humpel; Bradley T Hyman; Khalid Iqbal; Mathias Jucker; Stephan A Kaeser; Elmar Kaiser; Elisabeth Kapaki; Daniel Kidd; Peter Klivenyi; Cindy S Knudsen; Markus P Kummer; Piotr Lewczuk; Qiao-Xin Li; Albert Lladó; James Lui; Ralph Martins; Colin L Masters; Ulf Andreasson; Hiroyuki Arai; Sat Dev Batish; Sergio Bernardini; Marinus A Blankenstein; Kaj Blennow
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2011;7(4):386-395.e6.
2011: Victor L Villemagne; Daniel M Skovronsky; Henri Tochon-Danguy; Uwe Ackermann; Gaël Chételat; John Drago; Sylvia Gong; Gareth Jones; Hank F Kung; Colin L Masters; Rachel S Mulligan; Nobuyuki Okamura; Graeme J O'Keefe; Svetlana Pejoska; Christopher C Rowe
In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease.
Archives of neurology 2011;68(7):905-12.
2011: Kerryn E Pike; Cassandra Szoeke; Giuseppe Verdile; Victor L Villemagne; David Ames; Gael Chételat; Kathryn A Ellis; Norm Good; Simon M Laws; Ralph N Martins; Colin L Masters; Christopher C Rowe
Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study.
Neuropsychologia 2011;49(9):2384-90.
2011: Claudia Santosa; Stefanie Rasche; Adel Barakat; Shayne A Bellingham; Michael Ho; Jiangli Tan; Andrew Hill; Colin L Masters; Catriona McLean; Geneviève Evin
Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein.
Neurobiology of disease 2011;43(1):176-83.
2011: Genevieve M Klug; Colin L Masters; Amelia McGlade; Christiane Stehmann; Alison Boyd; Steven J Collins
Surveillance of Creutzfeldt-Jakob disease in Australia: update to December 2010.
Communicable diseases intelligence quarterly report 2011;35(2):149-53.
2011: Michelle T Fodero-Tavoletti; Nobuyuki Okamura; Shozo Furumoto; Rachel S Mulligan; Andrea R Connor; Catriona A McLean; Diana Cao; Angela Rigopoulos; Glenn A Cartwright; Graeme J O'Keefe; Sylvia Gong; Paul A Adlard; Kevin J Barnham; Christopher C Rowe; Colin L Masters; Yukitsuka Kudo; Roberto Cappai; Kazuhiko Yanai; Victor L Villemagne
18F-THK523: a novel in vivo tau imaging ligand for Alzheimer's disease.
Brain : a journal of neurology 2011;134(Pt 4):1089-100.
2011: V B Gupta; Simon Laws; Victor L Villemagne; D Ames; Ashley I Bush; K A Ellis; J K Lui; Colin L Masters; Christopher C Rowe; C Szoeke; Kevin Taddei; Ralph N Martins
Plasma apolipoprotein E and Alzheimer disease risk: the AIBL study of aging.
Neurology 2011;76(12):1091-8.
2011: Karla M Acevedo; Ya Hui Hung; Andrew H Dalziel; Qiao-Xin Li; Katrina Laughton; Krutika Wikhe; Alan Rembach; Blaine Roberts; Colin L Masters; Ashley I Bush; James Camakaris
Copper promotes the trafficking of the amyloid precursor protein.
The Journal of biological chemistry 2011;286(10):8252-62.
2011: Frances Corrigan; Chi L L Pham; Robert Vink; Peter C Blumbergs; Colin L Masters; Corinna van den Heuvel; Roberto Cappai
The neuroprotective domains of the amyloid precursor protein, in traumatic brain injury, are located in the two growth factor domains.
Brain research 2011;1378():137-43.
2011: Gaël Chételat; Victor L Villemagne; Kerryn E Pike; Kathryn A Ellis; Pierrick Bourgeat; Gareth Jones; Graeme J O'Keefe; Olivier Salvado; Cassandra Szoeke; Ralph N Martins; David Ames; Colin L Masters; Christopher C Rowe
Independent contribution of temporal beta-amyloid deposition to memory decline in the pre-dementia phase of Alzheimer's disease.
Brain : a journal of neurology 2011;134(Pt 3):798-807.
2011: Kathryn A Ellis; Christopher C Rowe; Cassandra E I Szoeke; Victor L Villemagne; David Ames; Gaël Chételat; Ralph N Martins; Colin L Masters; Jurgen Fripp; Oscar Acosta; Parnesh Raniga; Pierrick T Bourgeat; Olivier Salvado
Advances in structural and molecular neuroimaging in Alzheimer's disease.
The Medical journal of Australia 2011;194(4):S20-3.
2011: Simon J McBride; Cassandra E I Szoeke; Norm M Good; David Ames; Ralph N Martins; Colin L Masters; Paul T Maruff; Christopher C Rowe; Greg Savage; Kathryn A Ellis
A web-based normative data tool for assessing cognitive performance in healthy older Australians.
The Medical journal of Australia 2011;194(4):S12-4.
2011: Yan-Jiang Wang; Xin Wang; Jian-Jun Lu; Qiao-Xin Li; Chang-Yue Gao; Xiao-Hong Liu; Yin Sun; Miao Yang; Yoon Lim; Genevieve Evin; Jin-Hua Zhong; Colin L Masters; Xin-Fu Zhou
p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(6):2292-304.
2011: Simon C Drew; Cathryn L Haigh; Helen M J Klemm; Colin L Masters; Steven J Collins; Kevin J Barnham; Victoria A Lawson
Optical imaging detects apoptosis in the brain and peripheral organs of prion-infected mice.
Journal of neuropathology and experimental neurology 2011;70(2):143-50.
2011: Colin L Masters; Jillian J Kril; Glenda M Halliday; Roger Pamphlett; Steven Collins; Andrew F Hill; Catriona McLean
Overview and recent advances in neuropathology. Part 2: Neurodegeneration.
Pathology 2011;43(2):93-102.
2011: Giuseppe D Ciccotosto; Deborah J Tew; Simon C Drew; Danielle G Smith; Timothy Johanssen; Varsha Lal; Tong-Lay Crystal Lau; Keyla Perez; Cyril C Curtain; John D Wade; Frances Separovic; Colin L Masters; Jeffrey P Smith; Kevin J Barnham; Roberto Cappai
Stereospecific interactions are necessary for Alzheimer disease amyloid-β toxicity.
Neurobiology of aging 2011;32(2):235-48.
2011: Victor A Streltsov; Joseph N Varghese; Colin L Masters; Stewart D Nuttall
Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(4):1419-26.
2011: Jodi Meyerowitz; Dominic Ch Ng; Takashi Nonaka; Sarah J Parker; Katherine A Price; Laura J Vella; Marie A Bogoyevitch; Aphrodite Caragounis; Peter J Crouch; Masato Hasegawa; Katja M Kanninen; Qiao-Xin Li; Jeffrey R Liddell; Colin L Masters; Anthony R White
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress.
Molecular neurodegeneration 2011;6():57.
2011: Nastasia K-H Lim; Colin L Masters; Catriona A McLean; Christopher C Rowe; Cynthia P W Soon; Victor L Villemagne; Geneviève Evin; Katrina M Laughton; Qiao-Xin Li
Investigation of matrix metalloproteinases, MMP-2 and MMP-9, in plasma reveals a decrease of MMP-2 in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;26(4):779-86.
2011: Jean-Charles Lambert; Jean Dallongeville; Kathryn A Ellis; Susanna Schraen-Maschke; James Lui; Simon Laws; Julie Dumont; Florence Richard; Dominique Cottel; Claudine Berr; David Ames; Colin L Masters; Christopher C Rowe; Cassandra Szoeke; Christophe Tzourio; Jean-François Dartigues; Luc BUEE; Ralph Martins; Philippe Amouyel
Association of plasma Aß peptides with blood pressure in the elderly.
PloS one 2011;6(4):e18536.
2011: Gobhathai Sittironnarit; David Ames; Ashley I Bush; Noel Faux; Leon Flicker; Jonathan Foster; Sarah Hilmer; Nicola T Lautenschlager; Paul Maruff; Colin L Masters; Ralph N Martins; Christopher C Rowe; Cassandra Szoeke; Kathryn A Ellis
Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study.
Dementia and geriatric cognitive disorders 2011;31(3):173-8.
2011: Victor L Villemagne; Kerryn E Pike; Gaël Chételat; Kathryn A Ellis; Rachel S Mulligan; Pierrick Bourgeat; Uwe Ackermann; Gareth Jones; Cassandra Szoeke; Olivier Salvado; Ralph Martins; Graeme J O'Keefe; Chester A Mathis; William E Klunk; David Ames; Colin L Masters; Christopher C Rowe
Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease.
Annals of neurology 2011;69(1):181-92.
2011: Andrew D Watt; Keyla Perez; Noel G Faux; Kerryn E Pike; Christopher C Rowe; Pierrick Bourgeat; Olivier Salvado; Colin L Masters; Victor L Villemagne; Kevin J Barnham
Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24(1):47-59.
2010: Adam P Gunn; Colin L Masters; Robert A Cherny
Pyroglutamate-Aβ: role in the natural history of Alzheimer's disease.
The international journal of biochemistry & cell biology 2010;42(12):1915-8.
2010: Geneviève Evin; Adel Barakat; Colin L Masters
BACE: Therapeutic target and potential biomarker for Alzheimer's disease.
The international journal of biochemistry & cell biology 2010;42(12):1923-6.
2010: Steven J Collins; Amelia McGlade; Alison Boyd; Colin L Masters; Genevieve M J A Klug
14-3-3 protein detection and sporadic CJD: the status quo serves well while awaiting progress.
Journal of neurology, neurosurgery, and psychiatry 2010;81(11):1181.
2010: Gaël Chételat; Victor L Villemagne; Kerryn E Pike; Jean-Claude Baron; Pierrick Bourgeat; Gareth Jones; Noel G Faux; Kathryn A Ellis; Olivier Salvado; Cassandra Szoeke; Ralph N Martins; David Ames; Colin L Masters; Christopher C Rowe
Larger temporal volume in elderly with high versus low beta-amyloid deposition.
Brain : a journal of neurology 2010;133(11):3349-58.
2010: Peng Lei; Scott Ayton; David Finkelstein; Paul A Adlard; Colin L Masters; Ashley I Bush
Tau protein: relevance to Parkinson's disease.
The international journal of biochemistry & cell biology 2010;42(11):1775-8.
2010: Martin P Boland; Claire R Hatty; Frances Separovic; Andrew F Hill; Deborah J Tew; Kevin J Barnham; Cathryn L Haigh; Michael James; Colin L Masters; Steven J Collins
Anionic phospholipid interactions of the prion protein N terminus are minimally perturbing and not driven solely by the octapeptide repeat domain.
The Journal of biological chemistry 2010;285(42):32282-92.
2010: Sonia George; Su San Mok; Milawaty Nurjono; Scott Ayton; David Finkelstein; Colin L Masters; Qiao-Xin Li; Janetta G Culvenor
α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.
Journal of molecular neuroscience : MN 2010;42(2):243-54.
2010: Alison Boyd; Genevieve M J A Klug; Lawrence B Schonberger; Amelia McGlade; Jean-Philippe Brandel; Colin L Masters; Steven J Collins
Iatrogenic Creutzfeldt-Jakob disease in Australia: time to amend infection control measures for pituitary hormone recipients?
The Medical journal of Australia 2010;193(6):366-9.
2010: James A Duce; Andrew Tsatsanis; Michael A Cater; Simon A James; Elysia Robb; Krutika Wikhe; Su Ling Leong; Keyla Perez; Timothy Johanssen; Mark A Greenough; Hyun-Hee Cho; Denise Galatis; Robert D. Moir; Colin L Masters; Catriona McLean; Rudolph E Tanzi; Roberto Cappai; Kevin J Barnham; Giuseppe D Ciccotosto; Jack T Rogers; Ashley I Bush
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Cell 2010;142(6):857-67.
2010: Agata Rekas; Robert B Knott; Anna Sokolova; Kevin J Barnham; Keyla A Perez; Colin L Masters; Simon C Drew; Roberto Cappai; Cyril C Curtain; Chi L L Pham
The structure of dopamine induced alpha-synuclein oligomers.
European biophysics journal : EBJ 2010;39(10):1407-19.
2010: Christopher C Rowe; Kathryn A Ellis; Miroslava Rimajova; Pierrick Bourgeat; Kerryn E Pike; Gareth Jones; Jurgen Fripp; Henri Tochon-Danguy; Laurence Morandeau; Graeme O'Keefe; Roger Price; Parnesh Raniga; Peter Robins; Oscar Acosta; Nat Lenzo; Cassandra Szoeke; Olivier Salvado; Richard Head; Ralph Martins; Colin L Masters; David Ames; Victor L Villemagne
Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging.
Neurobiology of aging 2010;31(8):1275-83.
2010: Marcus Brazier; Irene Volitakis; Magda Kvasnicka; Anthony R White; John R Underwood; Jason E Green; Sen Han; Andrew Hill; Colin L Masters; Steven J Collins
Manganese chelation therapy extends survival in a mouse model of M1000 prion disease.
Journal of neurochemistry 2010;114(2):440-51.
2010: Rebecca M Nisbet; Christopher F Harrison; Victoria A Lawson; Colin L Masters; Roberto Cappai; Andrew Hill
Residues surrounding the glycosylphosphatidylinositol anchor attachment site of PrP modulate prion infection: insight from the resistance of rabbits to prion disease.
Journal of virology 2010;84(13):6678-86.
2010: Christopher F Harrison; Victoria A Lawson; Bradley M Coleman; Yong-Sun Kim; Colin L Masters; Roberto Cappai; Kevin J Barnham; Andrew Hill
Conservation of a glycine-rich region in the prion protein is required for uptake of prion infectivity.
The Journal of biological chemistry 2010;285(26):20213-23.
2010: Genevieve M Klug; Alison Boyd; Amelia McGlade; Christiane Stehmann; Colin L Masters; Steven J Collins
Surveillance of Creutzfeldt-Jakob disease in Australia: 2010 update.
Communicable diseases intelligence quarterly report 2010;34(2):96-101.
2010: Victoria M Perreau; Sandra Orchard; Paul A Adlard; Shayne A Bellingham; Roberto Cappai; Giuseppe D Ciccotosto; Tiffany F Cowie; Peter J Crouch; James A Duce; Geneviève Evin; Noel G Faux; Andrew Hill; Ya Hui Hung; Simon A James; Qiao-Xin Li; Su San Mok; Deborah J Tew; Anthony R White; Ashley I Bush; Henning Hermjakob; Colin L Masters
A domain level interaction network of amyloid precursor protein and Abeta of Alzheimer's disease.
Proteomics 2010;10(12):2377-95.
2010: Victor L Villemagne; Keyla Perez; Kerryn E Pike; W Mei Kok; Christopher C Rowe; Anthony R White; Pierrick Bourgeat; Olivier Salvado; Justin Bedo; Craig A Hutton; Noel G Faux; Colin L Masters; Kevin J Barnham
Blood-borne amyloid-beta dimer correlates with clinical markers of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(18):6315-22.
2010: Kathryn A Ellis; Christopher C Rowe; Victor L Villemagne; Ralph N Martins; Colin L Masters; Olivier Salvado; Cassandra Szoeke; David Ames
Addressing population aging and Alzheimer's disease through the Australian imaging biomarkers and lifestyle study: collaboration with the Alzheimer's Disease Neuroimaging Initiative.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2010;6(3):291-6.
2010: Aphrodite Caragounis; Katherine Ann Price; Cynthia P W Soon; Gulay Filiz; Colin L Masters; Qiao-Xin Li; Peter J Crouch; Anthony R White
Zinc induces depletion and aggregation of endogenous TDP-43.
Free radical biology & medicine 2010;48(9):1152-61.
2010: Wah Chin Boon; Maarten van den Buuse; Nico Wegener; Sally Martin; Hui Kheng Chua; Ashley I Bush; Colin L Masters; Paul A Adlard; Qiao-Xin Li
Behavioural phenotype of APPC100.V717F transgenic mice over-expressing a mutant Abeta-bearing fragment is associated with reduced NMDA receptor density.
Behavioural brain research 2010;209(1):27-35.
2010: Michel Guipponi; Qiao-Xin Li; Lavinia Hyde; Tim Beissbarth; Gordon K Smyth; Colin L Masters; Hamish S Scott
SAGE analysis of genes differentially expressed in presymptomatic TgSOD1G93A transgenic mice identified cellular processes involved in early stage of ALS pathology.
Journal of molecular neuroscience : MN 2010;41(1):172-82.
2010: Amee J George; Lavinia Gordon; Tim Beissbarth; Irene Koukoulas; R. M. Damian Holsinger; Victoria Perreau; Roberto Cappai; Seong-Seng Tan; Colin L Masters; Hamish S Scott; Qiao-Xin Li
A serial analysis of gene expression profile of the Alzheimer's disease Tg2576 mouse model.
Neurotoxicity research 2010;17(4):360-79.
2010: Cynthia P W Soon; Peter J Crouch; Bradley J Turner; Catriona A McLean; Katrina M Laughton; Julie D Atkin; Colin L Masters; Anthony R White; Qiao-Xin Li
Serum matrix metalloproteinase-9 activity is dysregulated with disease progression in the mutant SOD1 transgenic mice.
Neuromuscular disorders : NMD 2010;20(4):260-6.
2010: Steven J Collins; Maaike Schuur; Alison Boyd; Victoria Lewis; Genevieve M Klug; Amelia McGlade; Andrew van Oosterhout; Guido Breedveld; Ben A Oostra; Colin L Masters; Cornelia M Van Duijn
No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease.
Neuroscience letters 2010;472(1):16-8.
2010: Gaël Chételat; Victor L Villemagne; Pierrick Bourgeat; Kerryn E Pike; Gareth Jones; David Ames; Kathryn A Ellis; Cassandra Szoeke; Ralph N Martins; Graeme J O'Keefe; Olivier Salvado; Colin L Masters; Christopher C Rowe
Relationship between atrophy and beta-amyloid deposition in Alzheimer disease.
Annals of neurology 2010;67(3):317-24.
2010: Pierrick Bourgeat; G Chételat; Victor L Villemagne; Jurgen Fripp; Parnesh Raniga; K Pike; O Acosta; C Szoeke; Sébastien Ourselin; D Ames; K A Ellis; R N Martins; Colin L Masters; Christopher C Rowe; O Salvado
Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia.
Neurology 2010;74(2):121-7.
2010: Michael Ho; David E Hoke; Yee Jia Chua; Qiao-Xin Li; Janetta G Culvenor; Colin L Masters; Anthony R White; Geneviève Evin
Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.
International journal of Alzheimer's disease 2010;2011():950932.
2010: Simon C Drew; Colin L Masters; Kevin J Barnham
Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination.
PloS one 2010;5(12):e15875.
2010: Alex Bahar-Fuchs; Gaël Chételat; Victor L Villemagne; Simon Moss; Kerryn Pike; Colin L Masters; Christopher C Rowe; Greg Savage
Olfactory deficits and amyloid-β burden in Alzheimer's disease, mild cognitive impairment, and healthy aging: a PiB PET study.
Journal of Alzheimer's disease : JAD 2010;22(4):1081-7.
2010: Victoria A Lawson; Brooke Lumicisi; Jeremy Welton; Dorothy Machalek; Katrina Gouramanis; Helen M Klemm; James D Stewart; Colin L Masters; David E Hoke; Steven J Collins; Andrew Hill
Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein.
PloS one 2010;5(8):e12351.
2010: James K Lui; Simon Laws; Qiao-Xin Li; Victor L Villemagne; David Ames; Belinda Brown; Ashley I Bush; Karl De Ruyck; Jasmin Dromey; Kathryn A Ellis; Noel G Faux; Jonathan Foster; Christopher Fowler; Veer Gupta; Peter Hudson; Katrina Laughton; Colin L Masters; Kelly Pertile; Alan Rembach; Mira Rimajova; Mark Rodrigues; Christopher C Rowe; Rebecca Rumble; Cassandra Szoeke; Kevin Taddei; Tania Taddei; Brett Trounson; Vanessa Ward; Ralph N Martins
Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging.
Journal of Alzheimer's disease : JAD 2010;20(4):1233-42.
2010: Noel G Faux; Craig W Ritchie; Adam Gunn; Alan Rembach; Andrew Tsatsanis; Justin Bedo; John Edward Harrison; Lars Lannfelt; Kaj Blennow; Henrik Zetterberg; Martin Ingelsson; Colin L Masters; Rudolph E Tanzi; Jeffrey L Cummings; Caroline M Herd; Ashley I Bush
PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses.
Journal of Alzheimer's disease : JAD 2010;20(2):509-16.
2010: Victor L Villemagne; Kerryn Pike; Svetlana Pejoska; Alison Boyd; Margaret Power; Gareth Jones; Colin L Masters; Christopher C Rowe
11C-PiB PET ABri imaging in Worster-Drought syndrome (familial British dementia): a case report.
Journal of Alzheimer's disease : JAD 2010;19(2):423-8.
2010: Danielle G Smith; Giuseppe D Ciccotosto; Deborah J Tew; Keyla Perez; Cyril C Curtain; John F Boas; Colin L Masters; Roberto Cappai; Kevin J Barnham
Histidine 14 modulates membrane binding and neurotoxicity of the Alzheimer's disease amyloid-beta peptide.
Journal of Alzheimer's disease : JAD 2010;19(4):1387-400.
2009: Victor L Villemagne; Suzuka Ataka; Toshiki Mizuno; William S Brooks; Yasuhiro Wada; Masaki Kondo; Gareth Jones; Yasuyoshi Watanabe; Rachel Mulligan; Masanori Nakagawa; Takami Miki; Hiroyuki Shimada; Graeme J O'Keefe; Colin L Masters; Hiroshi Mori; Christopher C Rowe
High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types.
Archives of neurology 2009;66(12):1537-44.
2009: Katherine Ann Price; Aphrodite Caragounis; Brett M Paterson; Gulay Filiz; Irene Volitakis; Colin L Masters; Kevin J Barnham; Paul S Donnelly; Peter J Crouch; Anthony R White
Sustained activation of glial cell epidermal growth factor receptor by bis(thiosemicarbazonato) metal complexes is associated with inhibition of protein tyrosine phosphatase activity.
Journal of medicinal chemistry 2009;52(21):6606-20.
2009: Lis A Evered; Brendan S Silbert; David A Scott; Paul Maruff; Katrina M Laughton; Irene Volitakis; Tiffany Cowie; Robert A Cherny; Colin L Masters; Qiao-Xin Li
Plasma amyloid beta42 and amyloid beta40 levels are associated with early cognitive dysfunction after cardiac surgery.
The Annals of thoracic surgery 2009;88(5):1426-32.
2009: Victoria Lewis; Andrew Hill; Cathryn L Haigh; Genevieve M Klug; Colin L Masters; Victoria A Lawson; Steven J Collins
Increased proportions of C1 truncated prion protein protect against cellular M1000 prion infection.
Journal of neuropathology and experimental neurology 2009;68(10):1125-35.
2009: Rogan B Tinsley; Chris R Bye; Clare L Parish; Angela Tziotis-Vais; Sonia George; Janetta G Culvenor; Qiao-Xin Li; Colin L Masters; David Finkelstein; Malcolm K Horne
Dopamine D2 receptor knockout mice develop features of Parkinson disease.
Annals of neurology 2009;66(4):472-84.
2009: Michelle T Fodero-Tavoletti; Colin L Masters; Catriona A McLean; Kerryn E Pike; Christopher C Rowe; Paul A Adlard; Roberto Cappai; Andrea R Connor; Tiffany Cowie; Victor L Villemagne
Amyloid imaging in Alzheimer's disease and other dementias.
Brain imaging and behavior 2009;3(3):246-61.
2009: Cathryn L Haigh; Victoria A Lewis; Laura J Vella; Colin L Masters; Andrew Hill; Victoria A Lawson; Steven J Collins
PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site.
Cell research 2009;19(9):1062-78.
2009: Michelle T Fodero-Tavoletti; Rachel S Mulligan; Nobuyuki Okamura; Shozo Furumoto; Christopher C Rowe; Yukitsuka Kudo; Colin L Masters; Roberto Cappai; Kazuhiko Yanai; Victor L Villemagne
In vitro characterisation of BF227 binding to alpha-synuclein/Lewy bodies.
European journal of pharmacology 2009;617(1-3):54-8.
2009: Victor L Villemagne; Catriona A McLean; K Reardon; A Boyd; V Lewis; G Klug; G Jones; D Baxendale; Colin L Masters; Christopher C Rowe; S J Collins
11C-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry 2009;80(9):998-1001.
2009: R Michael Dutescu; Qiao-Xin Li; Jonathan G Crowston; Colin L Masters; Paul N Baird; Janetta G Culvenor
Amyloid precursor protein processing and retinal pathology in mouse models of Alzheimer's disease.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2009;247(9):1213-21.
2009: Gawain McColl; Blaine R Roberts; Adam P Gunn; Keyla A Perez; Deborah J Tew; Colin L Masters; Kevin J Barnham; Robert A Cherny; Ashley I Bush
The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42.
The Journal of biological chemistry 2009;284(34):22697-702.
2009: Ya Hui Hung; Elysia L Robb; Irene Volitakis; Michael Ho; Genevieve Evin; Qiao-Xin Li; Janetta G Culvenor; Colin L Masters; Robert A Cherny; Ashley I Bush
Paradoxical condensation of copper with elevated beta-amyloid in lipid rafts under cellular copper deficiency conditions: implications for Alzheimer disease.
The Journal of biological chemistry 2009;284(33):21899-907.
2009: Kathryn A Ellis; Ashley I Bush; David Darby; Daniela De Fazio; Jonathan Foster; Peter Hudson; Nicola T Lautenschlager; Nat Lenzo; Ralph N Martins; Paul Maruff; Colin L Masters; Andrew Milner; Kerryn Pike; Christopher C Rowe; Greg Savage; Cassandra Szoeke; Kevin Taddei; Victor L Villemagne; Michael Woodward; David Ames
The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease.
International psychogeriatrics / IPA 2009;21(4):672-87.
2009: Simon C Drew; Colin L Masters; Kevin J Barnham
Alanine-2 carbonyl is an oxygen ligand in Cu2+ coordination of Alzheimer's disease amyloid-beta peptide--relevance to N-terminally truncated forms.
Journal of the American Chemical Society 2009;131(25):8760-1.
2009: Christa J Maynard; Roberto Cappai; Irene Volitakis; Katrina M Laughton; Colin L Masters; Ashley I Bush; Qiao-Xin Li
Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice.
Cellular and molecular neurobiology 2009;29(5):757-67.
2009: Genevieve M Klug; Alison Boyd; Victoria Lewis; Amelia McGlade; Christiane Stehmann; Colin L Masters; Steven J Collins
Surveillance of Creutzfeldt-Jakob disease in Australia: 2009 update.
Communicable diseases intelligence quarterly report 2009;33(2):188-91.
2009: Cathryn L Haigh; Simon C Drew; Martin P Boland; Colin L Masters; Kevin J Barnham; Victoria A Lawson; Steven J Collins
Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response.
Journal of cell science 2009;122(Pt 10):1518-28.
2009: Su Ling Leong; Chi L L Pham; Denise Galatis; Michelle T Fodero-Tavoletti; Keyla Perez; Andrew Hill; Colin L Masters; Feda E Ali; Kevin J Barnham; Roberto Cappai
Formation of dopamine-mediated alpha-synuclein-soluble oligomers requires methionine oxidation.
Free radical biology & medicine 2009;46(10):1328-37.
2009: Jeffrey P Smith; Varsha Lal; David Bowser; Roberto Cappai; Colin L Masters; Giuseppe D Ciccotosto
Stimulus pattern dependence of the Alzheimer's disease amyloid-beta 42 peptide's inhibition of long term potentiation in mouse hippocampal slices.
Brain research 2009;1269():176-84.
2009: Kristyn Bates; Giuseppe Verdile; Q-X Li; D Ames; P Hudson; Colin L Masters; Ralph N Martins
Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.
Molecular psychiatry 2009;14(5):469-86.
2009: Paul A Adlard; Simon A James; Ashley I Bush; Colin L Masters
beta-Amyloid as a molecular therapeutic target in Alzheimer's disease.
Drugs of today (Barcelona, Spain : 1998) 2009;45(4):293-304.
2009: Prashant R Bharadwaj; Ashok K Dubey; Colin L Masters; Ralph N Martins; Ian Macreadie
Abeta aggregation and possible implications in Alzheimer's disease pathogenesis.
Journal of cellular and molecular medicine 2009;13(3):412-21.
2009: Peter J Crouch; Deborah J Tew; Tai Du; Diem Ngoc Nguyen; Aphrodite Caragounis; Gulay Filiz; Rachel E Blake; Ian A Trounce; Cynthia P W Soon; Katrina M Laughton; Keyla A Perez; Qiao-Xin Li; Robert A Cherny; Colin L Masters; Kevin J Barnham; Anthony R White
Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
Journal of neurochemistry 2009;108(5):1198-207.
2009: Remy Robert; Olan Dolezal; Lynne Waddington; Meghan K Hattarki; Roberto Cappai; Colin L Masters; Peter J Hudson; Kim L Wark
Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.
Protein engineering, design & selection : PEDS 2009;22(3):199-208.
2009: Marcus Brazier; Vanessa A Wall; Barry W Brazier; Colin L Masters; Steven J Collins
Therapeutic interventions ameliorating prion disease.
Expert review of anti-infective therapy 2009;7(1):83-105.
2009: Katherine A Price; Peter J Crouch; Paul S Donnelly; Colin L Masters; Anthony R White; Cyril C Curtain
Membrane-targeted strategies for modulating APP and Abeta-mediated toxicity.
Journal of cellular and molecular medicine 2009;13(2):249-61.
2009: Michelle T Fodero-Tavoletti; Christopher C Rowe; Catriona A McLean; Laura Leone; Qiao-Xin Li; Colin L Masters; Roberto Cappai; Victor L Villemagne
Characterization of PiB binding to white matter in Alzheimer disease and other dementias.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(2):198-204.
2009: Genevieve M Klug; Handan Wand; Alison Boyd; Matthew Law; Scott Whyte; John Kaldor; Colin L Masters; Steven Collins
Enhanced geographically restricted surveillance simulates sporadic Creutzfeldt-Jakob disease cluster.
Brain : a journal of neurology 2009;132(Pt 2):493-501.
2009: Simon C Drew; Christopher J Noble; Colin L Masters; Graeme R Hanson; Kevin J Barnham
Pleomorphic copper coordination by Alzheimer's disease amyloid-beta peptide.
Journal of the American Chemical Society 2009;131(3):1195-207.
2009: Peter J Crouch; Lin Wai Hung; Paul A Adlard; Mikhalina Cortes; Varsha Lal; Gulay Filiz; Keyla Perez; Milawaty Nurjono; Aphrodite Caragounis; Tai Du; Katrina Laughton; Irene Volitakis; Ashley I Bush; Qiao-Xin Li; Colin L Masters; Roberto Cappai; Robert A Cherny; Paul S Donnelly; Anthony R White; Kevin J Barnham
Increasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):381-6.
2009: Shayne A Bellingham; Louise A Coleman; Colin L Masters; James Camakaris; Andrew Hill
Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.
The Journal of biological chemistry 2009;284(2):1291-301.
2009: Lev G Goldfarb; Vsevolod A Vladimirtsev; Fyodor A Platanov; Hee-Suk Lee; Catriona A McLean; Colin L Masters
Viliuisk encephalomyelitis in Eastern Siberia - analysis of 390 cases.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2009;47(2):171-81.
2009: Yif'at Biran; Colin L Masters; Kevin J Barnham; Ashley I Bush; Paul A Adlard
Pharmacotherapeutic targets in Alzheimer's disease.
Journal of cellular and molecular medicine 2009;13(1):61-86.
2008: P Edison; Christopher C Rowe; J O Rinne; S Ng; I Ahmed; N Kemppainen; Victor L Villemagne; G O'Keefe; K Någren; K R Chaudhury; Colin L Masters; David J Brooks
Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.
Journal of neurology, neurosurgery, and psychiatry 2008;79(12):1331-8.
2008: Jurgen Fripp; Pierrick Bourgeat; Oscar Acosta; Parnesh Raniga; Marc Modat; Kerryn E Pike; Gareth Jones; Graeme O'Keefe; Colin L Masters; David Ames; Kathryn A Ellis; Paul Maruff; Jon Currie; Victor L Villemagne; Christopher C Rowe; Olivier Salvado; Sébastien Ourselin
Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging.
NeuroImage 2008;43(3):430-9.
2008: Lin Wai Hung; Giuseppe D Ciccotosto; Eleni Giannakis; Deborah J Tew; Keyla Perez; Colin L Masters; Roberto Cappai; John D Wade; Kevin J Barnham
Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(46):11950-8.
2008: Parnesh Raniga; Pierrick Bourgeat; Jurgen Fripp; Oscar Acosta; Victor L Villemagne; Christopher C Rowe; Colin L Masters; Gareth Jones; Graeme O'Keefe; Olivier Salvado; Sébastien Ourselin
Automated (11)C-PiB standardized uptake value ratio.
Academic radiology 2008;15(11):1376-89.
2008: Victor A Streltsov; Stephen J Titmuss; V Chandana Epa; Kevin J Barnham; Colin L Masters; Joseph N Varghese
The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease.
Biophysical journal 2008;95(7):3447-56.
2008: Lars Lannfelt; Kaj Blennow; Henrik Zetterberg; Stellan Batsman; David Ames; John Edward Harrison; Colin L Masters; Steve Targum; Ashley I Bush; Ross Murdoch; Janet Wilson; Craig W Ritchie
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial.
Lancet neurology 2008;7(9):779-86.
2008: Victor L Villemagne; Michelle T Fodero-Tavoletti; Kerryn E Pike; Roberto Cappai; Colin L Masters; Christopher C Rowe
The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias.
Molecular neurobiology 2008;38(1):1-15.
2008: Marcus Brazier; Susan R Doctrow; Colin L Masters; Steven J Collins
A manganese-superoxide dismutase/catalase mimetic extends survival in a mouse model of human prion disease.
Free radical biology & medicine 2008;45(2):184-92.
2008: Paul A Adlard; Robert A Cherny; David Finkelstein; Elisabeth Gautier; Elysia Robb; Mikhalina Cortes; Irene Volitakis; Xiang Liu; Jeffrey P Smith; Keyla Perez; Katrina Laughton; Qiao-Xin Li; Susan A Charman; Joseph A Nicolazzo; Simon Wilkins; Karolina Deleva; Toni Lynch; Gaik Kok; Craig W Ritchie; Rudolph E Tanzi; Roberto Cappai; Colin L Masters; Kevin J Barnham; Ashley I Bush
Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.
Neuron 2008;59(1):43-55.
2008: Simon C Drew; Su Ling Leong; Chi L L Pham; Deborah J Tew; Colin L Masters; Luke A Miles; Roberto Cappai; Kevin J Barnham
Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy.
Journal of the American Chemical Society 2008;130(24):7766-73.
2008: Genevieve M Klug; Alison Boyd; Victoria Lewis; Amelia R McGlade; Helene Roberts; Samantha L Douglass; Colin L Masters; Steven J Collins
Surveillance of Creutzfeldt-Jakob disease in Australia: 2008.
Communicable diseases intelligence quarterly report 2008;32(2):232-6.
2008: B E Needham; M E Wlodek; G D Ciccotosto; B C Fam; Colin L Masters; Joseph Proietto; Sofianos Andrikopoulos; Roberto Cappai
Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth.
The Journal of pathology 2008;215(2):155-63.
2008: Kevin J Barnham; Vijaya Kenche; Giuseppe D Ciccotosto; David P Smith; Deborah J Tew; Xiang Liu; Keyla Perez; Greg A Cranston; Timothy J Johanssen; Irene Volitakis; Ashley I Bush; Colin L Masters; Anthony R White; Jeffrey P Smith; Robert A Cherny; Roberto Cappai
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(19):6813-8.
2008: Kwok S Wun; Luke A Miles; Gabriela A N Crespi; Kaye Wycherley; David B Ascher; Kevin J Barnham; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Michael W Parker; William J McKinstry
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 5):438-41.
2008: Tai Du; Sharon L La Fontaine; Michael Abdo; Shayne A Bellingham; Mark Greenough; Irene Volitakis; Robert A Cherny; Ashley I Bush; Peter J Hudson; James Camakaris; Julian F B Mercer; Peter J Crouch; Colin L Masters; Victoria M Perreau; Anthony R White
Investigating copper-regulated protein expression in Menkes fibroblasts using antibody microarrays.
Proteomics 2008;8(9):1819-31.
2008: Robyn A Sharples; Laura J Vella; Rebecca M Nisbet; Ryan Naylor; Keyla Perez; Kevin J Barnham; Colin L Masters; Andrew Hill
Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(5):1469-78.
2008: Sonia George; Maarten van den Buuse; Su San Mok; Colin L Masters; Qiao-Xin Li; Janetta G Culvenor
Alpha-synuclein transgenic mice exhibit reduced anxiety-like behaviour.
Experimental neurology 2008;210(2):788-92.
2008: Eleni Giannakis; Jessica Pacífico; David P Smith; Lin Wai Hung; Colin L Masters; Roberto Cappai; John D Wade; Kevin J Barnham
Dimeric structures of alpha-synuclein bind preferentially to lipid membranes.
Biochimica et biophysica acta 2008;1778(4):1112-9.
2008: Deborah J Tew; Stephen P Bottomley; David P Smith; Giuseppe D Ciccotosto; jeffrey babon; Mark G Hinds; Colin L Masters; Roberto Cappai; Kevin J Barnham
Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide.
Biophysical journal 2008;94(7):2752-66.
2008: Luke A Miles; Kwok S Wun; Gabriela A N Crespi; Michelle T Fodero-Tavoletti; Denise Galatis; Christopher J Bagley; Konrad Beyreuther; Colin L Masters; Roberto Cappai; William J McKinstry; Kevin J Barnham; Michael W Parker
Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope.
Journal of molecular biology 2008;377(1):181-92.
2008: Paul S Donnelly; Aphrodite Caragounis; Tai Du; Katrina M Laughton; Irene Volitakis; Robert A Cherny; Robyn A Sharples; Andrew Hill; Qiao-Xin Li; Colin L Masters; Kevin J Barnham; Anthony R White
Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.
The Journal of biological chemistry 2008;283(8):4568-77.
2008: David P Smith; Deborah J Tew; Andrew Hill; Stephen P Bottomley; Colin L Masters; Kevin J Barnham; Roberto Cappai
Formation of a high affinity lipid-binding intermediate during the early aggregation phase of alpha-synuclein.
Biochemistry 2008;47(5):1425-34.
2008: J Weaver Cargin; Alexander Collie; Colin L Masters; Paul Maruff
The nature of cognitive complaints in healthy older adults with and without objective memory decline.
Journal of clinical and experimental neuropsychology 2008;30(2):245-57.
2008: Christopher C Rowe; Uwe Ackerman; William Browne; Rachel Mulligan; Kerryn L Pike; Graeme J O'Keefe; Henri Tochon-Danguy; Gordon Chan; Salvatore U Berlangieri; Gareth Jones; Kerryn L Dickinson-Rowe; Hank P Kung; Wei Zhang; Mei Ping Kung; Daniel Skovronsky; Thomas Dyrks; Gerhard Holl; Sabine Krause; Matthias Friebe; Lutz Lehman; Stefanie Lindemann; Ludger M Dinkelborg; Colin L Masters; Victor L Villemagne
Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism.
Lancet neurology 2008;7(2):129-35.
2008: Victoria A Lawson; Laura J Vella; James D Stewart; Robyn A Sharples; Helen Klemm; Dorothy M Machalek; Colin L Masters; Roberto Cappai; Steven J Collins; Andrew Hill
Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.
The international journal of biochemistry & cell biology 2008;40(12):2793-801.
2008: Katherine A Price; Gulay Filiz; Aphrodite Caragounis; Tai Du; Katrina M Laughton; Colin L Masters; Robyn A Sharples; Andrew Hill; Qiao-Xin Li; Paul S Donnelly; Kevin J Barnham; Peter J Crouch; Anthony R White
Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
The international journal of biochemistry & cell biology 2008;40(9):1901-17.
2008: Victor L Villemagne; K E Pike; D Darby; Paul Maruff; G Savage; Steven Ng; U Ackermann; T F Cowie; J Currie; S G Chan; G Jones; Henri Tochon-Danguy; G O'Keefe; Colin L Masters; Christopher C Rowe
Abeta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease.
Neuropsychologia 2008;46(6):1688-97.
2008: Gulay Filiz; Aphrodite Caragounis; Laura Bica; Tai Du; Colin L Masters; Peter J Crouch; Anthony R White
Clioquinol inhibits peroxide-mediated toxicity through up-regulation of phosphoinositol-3-kinase and inhibition of p53 activity.
The international journal of biochemistry & cell biology 2008;40(5):1030-42.
2008: Tai Du; Giuseppe D Ciccotosto; Greg A Cranston; Gulcan Kocak; Colin L Masters; Peter J Crouch; Roberto Cappai; Anthony R White
Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation.
Free radical biology & medicine 2008;44(1):44-55.
2008: Peter J Crouch; Susan-Marie E Harding; Anthony R White; James Camakaris; Ashley I Bush; Colin L Masters
Mechanisms of A beta mediated neurodegeneration in Alzheimer's disease.
The international journal of biochemistry & cell biology 2008;40(2):181-98.
2007: Tong-Lay Crystal Lau; John D Gehman; John D Wade; Colin L Masters; Kevin J Barnham; Frances Separovic
Cholesterol and Clioquinol modulation of A beta(1-42) interaction with phospholipid bilayers and metals.
Biochimica et biophysica acta 2007;1768(12):3135-44.
2007: Kerryn E Pike; Greg Savage; Victor L Villemagne; Steven Ng; Simon A Moss; Paul Maruff; Chester A Mathis; William E Klunk; Colin L Masters; Christopher C Rowe
Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease.
Brain : a journal of neurology 2007;130(Pt 11):2837-44.
2007: Aphrodite Caragounis; Tai Du; Gulay Filiz; Katrina M Laughton; Irene Volitakis; Robyn A Sharples; Robert A Cherny; Colin L Masters; Simon C Drew; Andrew Hill; Qiao-Xin Li; Peter J Crouch; Kevin J Barnham; Anthony R White
Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
The Biochemical journal 2007;407(3):435-50.
2007: J Weaver Cargin; Paul Maruff; Alexander Collie; Ruxsana Shafiq-Antonacci; Colin L Masters
Decline in verbal memory in non-demented older adults.
Journal of clinical and experimental neuropsychology 2007;29(7):706-18.
2007: Victoria A Lawson; James D Stewart; Colin L Masters
Enzymatic detergent treatment protocol that reduces protease-resistant prion protein load and infectivity from surgical-steel monofilaments contaminated with a human-derived prion strain.
The Journal of general virology 2007;88(Pt 10):2905-14.
2007: Tong-Lay Crystal Lau; John D Gehman; John D Wade; Keyla Perez; Colin L Masters; Kevin J Barnham; Frances Separovic
Membrane interactions and the effect of metal ions of the amyloidogenic fragment Abeta(25-35) in comparison to Abeta(1-42).
Biochimica et biophysica acta 2007;1768(10):2400-8.
2007: Michelle T Fodero-Tavoletti; David P Smith; Catriona A McLean; Paul A Adlard; Kevin J Barnham; Lisa E Foster; Laura Leone; Keyla Perez; Mikhalina Cortés; Janetta G Culvenor; Qiao-Xin Li; Katrina M Laughton; Christopher C Rowe; Colin L Masters; Roberto Cappai; Victor L Villemagne
In vitro characterization of Pittsburgh compound-B binding to Lewy bodies.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(39):10365-71.
2007: Vsevolod A Vladimirtsev; Raisa S Nikitina; Neil Renwick; Anastasia A Ivanova; Al'bina P Danilova; Fyodor A Platonov; Vadim G Krivoshapkin; Catriona A McLean; Colin L Masters; D Carleton Gajdusek; Lev G Goldfarb
Family clustering of Viliuisk encephalomyelitis in traditional and new geographic regions.
Emerging infectious diseases 2007;13(9):1321-6.
2007: Per Westermark; Merrill D Benson; Joel N Buxbaum; Alan S Cohen; Blas Frangione; Shu-Ichi Ikeda; Colin L Masters; Giampaolo Merlini; Maria J Saraiva; Jean D Sipe
A primer of amyloid nomenclature.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2007;14(3):179-83.
2007: Steven Y Ng; Victor L Villemagne; Colin L Masters; Christopher C Rowe
Evaluating atypical dementia syndromes using positron emission tomography with carbon 11 labeled Pittsburgh Compound B.
Archives of neurology 2007;64(8):1140-4.
2007: Heather L Melrose; C B Kent; Julie P Taylor; J C Dachsel; Kelly M Hinkle; Sarah J Lincoln; Su San Mok; Janetta G Culvenor; Colin L Masters; Glenn M Tyndall; D I Bass; Zeshan Ahmed; Cathy Andorfer; Owen A Ross; Zbigniew K Wszolek; A Delldonne; dennis dickson; Matthew J Farrer
A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease.
Neuroscience 2007;147(4):1047-58.
2007: Genevieve M Klug; Alison Boyd; Victoria Lewis; Samantha L Douglass; Helene Roberts; Rebecca Argent; Colin L Masters; Steven J Collins
Creutzfeldt-Jakob disease: Australian surveillance update to March 2007.
Communicable diseases intelligence quarterly report 2007;31(2):194-7.
2007: Christopher C Rowe; Steven Ng; U Ackermann; Sylvia J Gong; K Pike; G Savage; T F Cowie; K L Dickinson; Paul Maruff; D Darby; C Smith; M Woodward; John R Merory; Henri Tochon-Danguy; Graeme J O'Keefe; William E Klunk; Chester A Mathis; J C Price; Colin L Masters; Victor L Villemagne
Imaging beta-amyloid burden in aging and dementia.
Neurology 2007;68(20):1718-25.
2007: Steven Ng; Victor L Villemagne; Salvatore U Berlangieri; Sze-Ting Lee; Martin Cherk; Sylvia J Gong; Uwe Ackermann; Tim Saunder; Henri Tochon-Danguy; Gareth Jones; Clare Smith; Graeme J O'Keefe; Colin L Masters; Christopher C Rowe
Visual assessment versus quantitative assessment of 11C-PIB PET and 18F-FDG PET for detection of Alzheimer's disease.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(4):547-52.
2007: L J Vella; Robyn A Sharples; Victoria A Lawson; Colin L Masters; Roberto Cappai; Andrew Hill
Packaging of prions into exosomes is associated with a novel pathway of PrP processing.
The Journal of pathology 2007;211(5):582-90.
2007: Qiao-Xin Li; Su San Mok; Katrina M Laughton; Catriona A McLean; Roberto Cappai; Colin L Masters; Janetta G Culvenor; Malcolm K Horne
Plasma alpha-synuclein is decreased in subjects with Parkinson's disease.
Experimental neurology 2007;204(2):583-8.
2007: Geoffrey K-W Kong; Julian J Adams; Hugh H Harris; John F Boas; Cyril C Curtain; Denise Galatis; Colin L Masters; Kevin J Barnham; William J McKinstry; Roberto Cappai; Michael W Parker
Structural studies of the Alzheimer's amyloid precursor protein copper-binding domain reveal how it binds copper ions.
Journal of molecular biology 2007;367(1):148-61.
2007: Dominic Rowe; V Lewis; M Needham; M Rodriguez; A Boyd; C McLean; H Roberts; Colin L Masters; S J Collins
Novel prion protein gene mutation presenting with subacute PSP-like syndrome.
Neurology 2007;68(11):868-70.
2007: David P Smith; Giuseppe D Ciccotosto; Deborah J Tew; Michelle T Fodero-Tavoletti; Timothy Johanssen; Colin L Masters; Kevin J Barnham; Roberto Cappai
Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.
Biochemistry 2007;46(10):2881-91.
2007: Zeinab Khalil; Dina LoGiudice; Bereha Khodr; P Maruff; Colin L Masters
Impaired peripheral endothelial microvascular responsiveness in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2007;11(1):25-32.
2007: Simon Melov; Paul A Adlard; Karl J Morten; Felicity Johnson; Tamara R Golden; Douglas Hinerfeld; Birgit Schilling; Christine Mavros; Colin L Masters; Irene Volitakis; Qiao-Xin Li; Katrina Laughton; Alan Hubbard; Robert A Cherny; Bradford Gibson; Ashley I Bush
Mitochondrial oxidative stress causes hyperphosphorylation of tau.
PloS one 2007;2(6):e536.
2006: Colin L Masters; Konrad Beyreuther
Alzheimer's centennial legacy: prospects for rational therapeutic intervention targeting the Abeta amyloid pathway.
Brain : a journal of neurology 2006;129(Pt 11):2823-39.
2006: Chou Hung Sim; Daisy Sio Seng Lio; Su San Mok; Colin L Masters; Andrew Hill; Janetta G Culvenor; Heung-Chin Cheng
C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1.
Human molecular genetics 2006;15(21):3251-62.
2006: Peter J Crouch; Kevin J Barnham; James A Duce; Rachel E Blake; Colin L Masters; Ian A Trounce
Copper-dependent inhibition of cytochrome c oxidase by Abeta(1-42) requires reduced methionine at residue 35 of the Abeta peptide.
Journal of neurochemistry 2006;99(1):226-36.
2006: Steven J Collins; Pascual Sanchez-Juan; Colin L Masters; Genevieve M Klug; C.M. Duijn; Anna Poleggi; Maurizio Pocchiari; Susanna Almonti; Natividad Cuadrado-Corrales; Jesús de Pedro-Cuesta; Herbert Budka; Ellen Gelpi; Markus Glatzel; M Tolnay; E Hewer; Inga Zerr; Uta Heinemann; H A Kretszchmar; Gerard H Jansen; E Olsen; Eva Mitrova; Annick Alpérovitch; Jean-Philippe Brandel; J Mackenzie; K Murray; Robert G Will
Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology 2006;129(Pt 9):2278-87.
2006: R. M. Damian Holsinger; James S Lee; Alison Boyd; Colin L Masters; Steven J Collins
CSF BACE1 activity is increased in CJD and Alzheimer disease versus [corrected] other dementias.
Neurology 2006;67(4):710-2.
2006: James A Duce; David P Smith; Rachel E Blake; Peter J Crouch; Qiao-Xin Li; Colin L Masters; Ian A Trounce
Linker histone H1 binds to disease associated amyloid-like fibrils.
Journal of molecular biology 2006;361(3):493-505.
2006: Kevin J Barnham; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Andrew Hill
Delineating common molecular mechanisms in Alzheimer's and prion diseases.
Trends in biochemical sciences 2006;31(8):465-72.
2006: Chor Hui Vivien Koh; Matthew Whiteman; Qiao-Xin Li; Barry Halliwell; Andrew Jenner; Boon-Seng Wong; Katrina M Laughton; Markus R Wenk; Colin L Masters; Philip M Beart; Ora Bernard; Nam Sang Cheung
Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.
Journal of neurochemistry 2006;98(4):1278-89.
2006: Anthony R White; Tai Du; Katrina M Laughton; Irene Volitakis; Robyn A Sharples; Michel E Xilinas; David E Hoke; R. M. Damian Holsinger; Geneviève Evin; Robert A Cherny; Andrew Hill; Kevin J Barnham; Qiao-Xin Li; Ashley I Bush; Colin L Masters
Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
The Journal of biological chemistry 2006;281(26):17670-80.
2006: David P Smith; Danielle G Smith; Cyril C Curtain; John F Boas; John R Pilbrow; Giuseppe D Ciccotosto; Tong-Lay Crystal Lau; Deborah J Tew; Keyla Perez; John D Wade; Ashley I Bush; Simon C Drew; Frances Separovic; Colin L Masters; Roberto Cappai; Kevin J Barnham
Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.
The Journal of biological chemistry 2006;281(22):15145-54.
2006: Colin L Masters; Roberto Cappai; Kevin J Barnham; Victor L Villemagne
Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.
Journal of neurochemistry 2006;97(6):1700-25.
2006: Christa Maynard; Roberto Cappai; Irene Volitakis; Robert A Cherny; Colin L Masters; Qiao-Xin Li; Ashley I Bush
Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology.
Journal of inorganic biochemistry 2006;100(5-6):952-62.
2006: Qiao-Xin Li; Su San Mok; Katrina M Laughton; Catriona A McLean; Irene Volitakis; Robert A Cherny; Nam Sang Cheung; Anthony R White; Colin L Masters
Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
Aging cell 2006;5(2):153-65.
2006: Amee J George; R. M. Damian Holsinger; Catriona A McLean; Seong-Seng Tan; Hamish Scott; Tina Cardamone; Roberto Cappai; Colin L Masters; Qiao-Xin Li
Decreased phosphatidylethanolamine binding protein expression correlates with Abeta accumulation in the Tg2576 mouse model of Alzheimer's disease.
Neurobiology of aging 2006;27(4):614-23.
2006: Matthias Gralle; Cristiano L P Oliveira; Luiz H Guerreiro; William J McKinstry; Denise Galatis; Colin L Masters; Roberto Cappai; Michael W Parker; Carlos H I Ramos; Iris Torriani; Sérgio T Ferreira
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein.
Journal of molecular biology 2006;357(2):493-508.
2006: C W Ritchie; Roberto Cappai; Colin L Masters
Clioquinol treatment in familiar early onset of Alzheimer's disease: Ibach B et al., Pharmacopsychiatry 2005; 38: 178-179.
Pharmacopsychiatry 2006;39(2):80.
2006: J Weaver Cargin; Paul Maruff; Alexander Collie; Colin L Masters
Mild memory impairment in healthy older adults is distinct from normal aging.
Brain and cognition 2006;60(2):146-55.
2006: Olav M Andersen; Vanessa Schmidt; Robert Spoelgen; Jørgen Gliemann; Joachim Behlke; Denise Galatis; William J McKinstry; Michael W Parker; Colin L Masters; Bradley T Hyman; Roberto Cappai; Thomas E Willnow
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Biochemistry 2006;45(8):2618-28.
2006: Tong-Lay Crystal Lau; Ernesto E Ambroggio; Deborah J Tew; Roberto Cappai; Colin L Masters; Gerardo D Fidelio; Kevin J Barnham; Frances Separovic
Amyloid-beta peptide disruption of lipid membranes and the effect of metal ions.
Journal of molecular biology 2006;356(3):759-70.
2006: Carlos Opazo; Sandra Luza; Victor L Villemagne; Irene Volitakis; Christopher C Rowe; Kevin J Barnham; Dorothea Strozyk; Colin L Masters; Robert A Cherny; Ashley I Bush
Radioiodinated clioquinol as a biomarker for beta-amyloid: Zn complexes in Alzheimer's disease.
Aging cell 2006;5(1):69-79.
2006: Marcus Brazier; Victoria Lewis; Giuseppe D Ciccotosto; Genevieve M Klug; Victoria A Lawson; Roberto Cappai; James W Ironside; Colin L Masters; Andrew Hill; Anthony R White; Steven Collins
Correlative studies support lipid peroxidation is linked to PrP(res) propagation as an early primary pathogenic event in prion disease.
Brain research bulletin 2006;68(5):346-54.
2006: Colin L Masters; Konrad Beyreuther
Pathways to the discovery of the Abeta amyloid of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):155-61.
2006: Geneviève Evin; M Fleur Sernee; Colin L Masters
Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies.
CNS drugs 2006;20(5):351-72.
2006: Genevieve M Klug; Alison Boyd; Victoria Lewis; Samantha L Douglass; Rebecca Argent; James S Lee; Colin L Masters; Steven J Collins
Creutzfeldt-Jakob disease: Australian surveillance update to December 2005.
Communicable diseases intelligence quarterly report 2006;30(1):144-7.
2006: Su San Mok; Dusan Losic; Colin J Barrow; Bradley J Turner; Colin L Masters; Lisandra L Martin; David Small
The beta-amyloid peptide of Alzheimer's disease decreases adhesion of vascular smooth muscle cells to the basement membrane.
Journal of neurochemistry 2006;96(1):53-64.
2005: Fang F Yuan; Sandra Biffin; Marcus Brazier; Monica Suarez; Roberto Cappai; Andrew Hill; Steven J Collins; John Sullivan; Deborah Middleton; Gerd Multhaup; Andrew F Geczy; Colin L Masters
Detection of prion epitopes on PrP and PrP of transmissible spongiform encephalopathies using specific monoclonal antibodies to PrP.
Immunology and cell biology 2005;83(6):632-7.
2005: Rony E Duncan; Martin B Delatycki; S J Collins; A Boyd; Colin L Masters; Julian Savulescu
Ethical considerations in presymptomatic testing for variant CJD.
Journal of medical ethics 2005;31(11):625-30.
2005: David E Hoke; Jiang-Li Tan; Nancy T Ilaya; Janetta G Culvenor; Stephanie J Smith; Anthony R White; Colin L Masters; Geneviève Evin
In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
The FEBS journal 2005;272(21):5544-57.
2005: Steven J Collins; Victoria Lewis; Marcus Brazier; Andrew Hill; Victoria A Lawson; Genevieve M Klug; Colin L Masters
Extended period of asymptomatic prion disease after low dose inoculation: assessment of detection methods and implications for infection control.
Neurobiology of disease 2005;20(2):336-46.
2005: Peter Soba; Simone Eggert; Katja Wagner; Hanswalter Zentgraf; Katjuscha Siehl; Sylvia Kreger; Alexander Löwer; Andreas Langer; Gunter Merdes; Renato Paro; Colin L Masters; Ulrike Müller; Stefan Kins; Konrad Beyreuther
Homo- and heterodimerization of APP family members promotes intercellular adhesion.
The EMBO journal 2005;24(20):3624-34.
2005: Olav M Andersen; Juliane Reiche; Vanessa Schmidt; Michael Gotthardt; Robert Spoelgen; Joachim Behlke; Christine A F Von Arnim; Tilman Breiderhoff; Pernille Jansen; Xin Wu; Kelly R Bales; Roberto Cappai; Colin L Masters; Jørgen Gliemann; Elliott J Mufson; Bradley T Hyman; Steven M Paul; Anders Nykjaer; Thomas E Willnow
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(38):13461-6.
2005: Natalia Yarovaya; Robert Schot; Lisa Fodero; Michelle McMahon; Alexis Mahoney; Rachael Williams; Elly Verbeek; An de Bondt; Mark Hampson; Peter van der Spek; Andrew Stubbs; Colin L Masters; Frans W Verheijen; Grazia M S Mancini; Deon J Venter
Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated.
Neurobiology of disease 2005;19(3):351-65.
2005: Roberto Cappai; Su-Ling Leck; Deborah J Tew; Nicholas A Williamson; David P Smith; Denise Galatis; Robyn A Sharples; Cyril C Curtain; Feda E Ali; Robert A Cherny; Janetta G Culvenor; Stephen P Bottomley; Colin L Masters; Kevin J Barnham; Andrew Hill
Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1377-9.
2005: Victoria Lewis; Andrew Hill; Genevieve M Klug; Alison Boyd; Colin L Masters; Steven J Collins
Australian sporadic CJD analysis supports endogenous determinants of molecular-clinical profiles.
Neurology 2005;65(1):113-8.
2005: Christa Maynard; Ashley I Bush; Colin L Masters; Roberto Cappai; Qiao-Xin Li
Metals and amyloid-beta in Alzheimer's disease.
International journal of experimental pathology 2005;86(3):147-59.
2005: Feda E Ali; Frances Separovic; Colin J Barrow; Robert A Cherny; Fiona Fraser; Ashley I Bush; Colin L Masters; Kevin J Barnham
Methionine regulates copper/hydrogen peroxide oxidation products of Abeta.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(6):353-60.
2005: Victoria A Lawson; Steven J Collins; Colin L Masters; Andrew Hill
Prion protein glycosylation.
Journal of neurochemistry 2005;93(4):793-801.
2005: Roberto Cappai; Fang Cheng; Giuseppe D Ciccotosto; B Elise Needham; Colin L Masters; Gerd Multhaup; Lars-Ake Fransson; Katrin Mani
The amyloid precursor protein (APP) of Alzheimer disease and its paralog, APLP2, modulate the Cu/Zn-Nitric Oxide-catalyzed degradation of glypican-1 heparan sulfate in vivo.
The Journal of biological chemistry 2005;280(14):13913-20.
2005: Anna K Tickler; Danielle G Smith; Giuseppe D Ciccotosto; Deborah J Tew; Cyril C Curtain; Darryl Carrington; Colin L Masters; Ashley I Bush; Robert A Cherny; Roberto Cappai; John D Wade; Kevin J Barnham
Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity.
The Journal of biological chemistry 2005;280(14):13355-63.
2005: Victor L Villemagne; Christopher C Rowe; S Macfarlane; Kathy E Novakovic; Colin L Masters
Imaginem oblivionis: the prospects of neuroimaging for early detection of Alzheimer's disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005;12(3):221-30.
2005: Geneviève Evin; Louise Canterford; David E Hoke; Robyn A Sharples; Janetta G Culvenor; Colin L Masters
Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
Biochemistry 2005;44(11):4332-41.
2005: Per Westermark; Merrill D Benson; Joel N Buxbaum; Alan S Cohen; Blas Frangione; Shu-Ichi Ikeda; Colin L Masters; Giampaolo Merlini; Maria J Saraiva; Jean D Sipe
Amyloid: toward terminology clarification. Report from the Nomenclature Committee of the International Society of Amyloidosis.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2005;12(1):1-4.
2005: Peter J Crouch; Rachel Blake; James A Duce; Giuseppe D Ciccotosto; Qiao-Xin Li; Kevin J Barnham; Cyril C Curtain; Robert A Cherny; Roberto Cappai; Thomas Dyrks; Colin L Masters; Ian A Trounce
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(3):672-9.
2005: Geoffrey K-W Kong; Denise Galatis; Kevin J Barnham; Galina Polekhina; Julian J Adams; Colin L Masters; Roberto Cappai; Michael W Parker; William J McKinstry
Crystallization and preliminary crystallographic studies of the copper-binding domain of the amyloid precursor protein of Alzheimer's disease.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):93-5.
2005: Kathy E Novakovic; Victor L Villemagne; Christopher C Rowe; Colin L Masters
Rare genetically defined causes of dementia.
International psychogeriatrics / IPA 2005;17 Suppl 1():S149-94.
2005: Genevieve M Klug; Alison Boyd; Victoria Lewis; Madga Kvasnicka; James S Lee; Colin L Masters; Steven J Collins
Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004.
Communicable diseases intelligence quarterly report 2005;29(3):269-71.
2004: Bradley J Turner; Qiao-Xin Li; Katrina M Laughton; Colin L Masters; Elizabeth C Lopes; Julie D Atkin; Surindar S Cheema
Brain beta-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1.
Neurochemical research 2004;29(12):2281-6.
2004: Craig W Ritchie; Ashley I Bush; Colin L Masters
Metal-protein attenuating compounds and Alzheimer's disease.
Expert opinion on investigational drugs 2004;13(12):1585-92.
2004: Giuseppe D Ciccotosto; Deborah J Tew; Cyril C Curtain; Danielle Smith; Darryl Carrington; Colin L Masters; Ashley I Bush; Robert A Cherny; Roberto Cappai; Kevin J Barnham
Enhanced toxicity and cellular binding of a modified amyloid beta peptide with a methionine to valine substitution.
The Journal of biological chemistry 2004;279(41):42528-34.
2004: Shayne A Bellingham; Giuseppe D Ciccotosto; B Elise Needham; Lisa R Fodero; Anthony R White; Colin L Masters; Roberto Cappai; James Camakaris
Gene knockout of amyloid precursor protein and amyloid precursor-like protein-2 increases cellular copper levels in primary mouse cortical neurons and embryonic fibroblasts.
Journal of neurochemistry 2004;91(2):423-8.
2004: Nancy T Ilaya; Geneviève Evin; Colin L Masters; Janetta G Culvenor
Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
Journal of neurochemistry 2004;91(1):230-7.
2004: Kevin J Barnham; Fredrik Haeffner; Giuseppe D Ciccotosto; Cyril C Curtain; Deborah J Tew; Christine Mavros; Konrad Beyreuther; Darryl Carrington; Colin L Masters; Robert A Cherny; Roberto Cappai; Ashley I Bush
Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(12):1427-9.
2004: Margaret J Smith; Robyn A Sharples; Geneviève Evin; Catriona A McLean; Brian Dean; Geoffrey Pavey; Emmanuelle Fantino; Richard G H Cotton; Kazunori Imaizumi; Colin L Masters; Roberto Cappai; Janetta G Culvenor
Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex.
Brain research. Molecular brain research 2004;127(1-2):128-35.
2004: Agata Rekas; Christopher G Adda; J Andrew Aquilina; Kevin J Barnham; Margaret Sunde; Denise Galatis; Nicholas A Williamson; Colin L Masters; Robin F Anders; Carol V Robinson; Roberto Cappai; John A Carver
Interaction of the molecular chaperone alphaB-crystallin with alpha-synuclein: effects on amyloid fibril formation and chaperone activity.
Journal of molecular biology 2004;340(5):1167-83.
2004: Amee J George; R. M. Damian Holsinger; Catriona A McLean; Katrina M Laughton; Konrad Beyreuther; Geneviève Evin; Colin L Masters; Qiao-Xin Li
APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.
Neurobiology of disease 2004;16(1):124-32.
2004: R. M. Damian Holsinger; Catriona A McLean; Steven J Collins; Colin L Masters; Geneviève Evin
Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.
Annals of neurology 2004;55(6):898-9.
2004: Simone Eggert; Krzysztof Paliga; Peter Soba; Geneviève Evin; Colin L Masters; Andreas Weidemann; Konrad Beyreuther
The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.
The Journal of biological chemistry 2004;279(18):18146-56.
2004: Shenggen Yao; Robert A Cherny; Ashley I Bush; Colin L Masters; Kevin J Barnham
Characterizing bathocuproine self-association and subsequent binding to Alzheimer's disease amyloid beta-peptide by NMR.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(4):210-7.
2004: Anthony R White; Kevin J Barnham; Xudong Huang; Irene Voltakis; Konrad Beyreuther; Colin L Masters; Robert A Cherny; Ashley I Bush; Roberto Cappai
Iron inhibits neurotoxicity induced by trace copper and biological reductants.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(3):269-80.
2004: Kevin J Barnham; Colin L Masters; Ashley I Bush
Neurodegenerative diseases and oxidative stress.
Nature reviews. Drug discovery 2004;3(3):205-14.
2004: Fiona J Brooke; Alison Boyd; Genevieve M Klug; Colin L Masters; Steven J Collins
Lyodura use and the risk of iatrogenic Creutzfeldt-Jakob disease in Australia.
The Medical journal of Australia 2004;180(4):177-81.
2004: Steven J Collins; Victoria A Lawson; Colin L Masters
Transmissible spongiform encephalopathies.
Lancet 2004;363(9402):51-61.
2004: Genevieve M Klug; Victoria Lewis; Alison Boyd; James S Lee; Colin L Masters; Steven J Collins
Creutzfeldt-Jakob disease surveillance in Australia January 1970 to December 2003.
Communicable diseases intelligence quarterly report 2004;28(3):356-8.
2004: P Maruff; Alexander Collie; David G Darby; J Weaver-Cargin; Colin L Masters; Jon Currie
Subtle memory decline over 12 months in mild cognitive impairment.
Dementia and geriatric cognitive disorders 2004;18(3-4):342-8.
2004: Janetta G Culvenor; Nancy T Ilaya; Michael T Ryan; Louise Canterford; David E Hoke; Nicholas A Williamson; Catriona A McLean; Colin L Masters; Geneviève Evin
Characterization of presenilin complexes from mouse and human brain using Blue Native gel electrophoresis reveals high expression in embryonic brain and minimal change in complex mobility with pathogenic presenilin mutations.
European journal of biochemistry / FEBS 2004;271(2):375-85.
2003: Craig W Ritchie; Ashley I Bush; Andrew Mackinnon; Stephen Macfarlane; Maree Mastwyk; Lachlan MacGregor; Lyn Kiers; Robert A Cherny; Qiao-Xin Li; Amanda Tammer; Darryl Carrington; Christine Mavros; Irene Volitakis; Michel E Xilinas; David Ames; Stephen Davis; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial.
Archives of neurology 2003;60(12):1685-91.
2003: Geneviève Evin; Aiqin Zhu; R. M. Damian Holsinger; Colin L Masters; Qiao-Xin Li
Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Journal of neuroscience research 2003;74(3):386-92.
2003: Janelle Nunan; Nicholas A Williamson; Andrew Hill; M Fleur Sernee; Colin L Masters; David Small
Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
Journal of neuroscience research 2003;74(3):378-85.
2003: Kevin J Barnham; Giuseppe D Ciccotosto; Anna K Tickler; Feda E Ali; Danielle G Smith; Nicholas A Williamson; Yuen-Han Lam; Darryl Carrington; Deborah J Tew; Gulcan Kocak; Irene Volitakis; Frances Separovic; Colin J Barrow; John D Wade; Colin L Masters; Robert A Cherny; Cyril C Curtain; Ashley I Bush; Roberto Cappai
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.
The Journal of biological chemistry 2003;278(44):42959-65.
2003: Randa Bahadi; Peter V Farrelly; Bronwyn L Kenna; Cyril C Curtain; Colin L Masters; Roberto Cappai; Kevin J Barnham; Joseph I Kourie
Cu2+-induced modification of the kinetics of A beta(1-42) channels.
American journal of physiology. Cell physiology 2003;285(4):C873-80.
2003: Ashley I Bush; Colin L Masters; Rudolph E Tanzi
Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(20):11193-4.
2003: Brian Dean; Simon Laws; Eugene Hone; Kevin Taddei; Elizabeth Scarr; Elizabeth A Thomas; Clive Harper; Catriona McClean; Colin L Masters; Nicola T Lautenschlager; Sam Gandy; Ralph N Martins
Increased levels of apolipoprotein E in the frontal cortex of subjects with schizophrenia.
Biological psychiatry 2003;54(6):616-22.
2003: Ruxsana Shafiq-Antonacci; Paul Maruff; Colin L Masters; Jon Currie
Spectrum of saccade system function in Alzheimer disease.
Archives of neurology 2003;60(9):1272-8.
2003: Judith Miklossy; Kevin Taddei; Domizio Suva; Giuseppe Verdile; Justin A Fonte; Christopher Fisher; Anastazija Gnjec; Joseph Ghika; Françoise Suard; Pankaj D Mehta; Catriona A McLean; Colin L Masters; William S Brooks; Ralph N Martins
Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease.
Neurobiology of aging 2003;24(5):655-62.
2003: Alison J E Green; Tatiana M Sivtseva; Al'bina P Danilova; Vladimir L Osakovsky; Vsevolod A Vladimirtsev; Martin Zeidler; R S G Knight; Feodor A Platonov; Alexey Shatunov; Vasili P Alekseev; Vadim G Krivoshapkin; Colin L Masters; D Carleton Gajdusek; Lev G Goldfarb
Viliuisk encephalomyelitis: intrathecal synthesis of oligoclonal IgG.
Journal of the neurological sciences 2003;212(1-2):69-73.
2003: Elizabeth A Thomas; Simon Laws; J Gregor Sutcliffe; Clive Harper; Brian Dean; Catriona McClean; Colin L Masters; Nicola T Lautenschlager; Sam Gandy; Ralph N Martins
Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer's disease: no relation to apolipoprotein E expression or genotype.
Biological psychiatry 2003;54(2):136-41.
2003: Dirk Beher; Michael Fricker; Alan Nadin; Earl E Clarke; Jonathan D J Wrigley; Yueming Li; Janetta G Culvenor; Colin L Masters; Timothy Harrison; Mark S Shearman
In vitro characterization of the presenilin-dependent gamma-secretase complex using a novel affinity ligand.
Biochemistry 2003;42(27):8133-42.
2003: Victoria Lewis; Steven Collins; Andrew Hill; Alison Boyd; Catriona A McLean; M Smith; Colin L Masters
Novel prion protein insert mutation associated with prolonged neurodegenerative illness.
Neurology 2003;60(10):1620-4.
2003: Kevin J Barnham; William J McKinstry; Gerd Multhaup; Denise Galatis; Craig J Morton; Cyril C Curtain; Nicholas A Williamson; Anthony R White; Mark G Hinds; Raymond S Norton; Konrad Beyreuther; Colin L Masters; Michael W Parker; Roberto Cappai
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
The Journal of biological chemistry 2003;278(19):17401-7.
2003: Joseph I Kourie; Bronwyn L Kenna; D Tew; M F Jobling; Cyril C Curtain; Colin L Masters; Kevin J Barnham; Roberto Cappai
Copper modulation of ion channels of PrP[106-126] mutant prion peptide fragments.
The Journal of membrane biology 2003;193(1):35-45.
2003: Lee E Goldstein; Julien A Muffat; Robert A Cherny; Robert D. Moir; Maria H Ericsson; Xudong Huang; Christine Mavros; Jennifer A Coccia; Kyle Y Faget; Karlotta A Fitch; Colin L Masters; Rudolph E Tanzi; Leo T Chylack; Ashley I Bush
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease.
Lancet 2003;361(9365):1258-65.
2003: Anthony R White; Fran Maher; Marcus Brazier; Michael F Jobling; James Thyer; Leanne R Stewart; Andrew Thompson; Riki Gibson; Colin L Masters; Gerd Multhaup; Konrad Beyreuther; Colin J Barrow; Steven J Collins; Roberto Cappai
Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.
Brain research 2003;966(2):231-44.
2003: Beate Grziwa; Marcus Otto Walter Grimm; Colin L Masters; Konrad Beyreuther; Tobias Hartmann; Stefan F Lichtenthaler
The transmembrane domain of the amyloid precursor protein in microsomal membranes is on both sides shorter than predicted.
The Journal of biological chemistry 2003;278(9):6803-8.
2003: M Fleur Sernee; Geneviève Evin; Janetta G Culvenor; Jose A Villadangos; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Selecting cells with different Alzheimer's disease gamma-secretase activity using FACS. Differential effect on presenilin exon 9 gamma- and epsilon-cleavage.
European journal of biochemistry / FEBS 2003;270(3):495-506.
2003: Cyril C Curtain; Feda E Ali; Danielle G Smith; Ashley I Bush; Colin L Masters; Kevin J Barnham
Metal ions, pH, and cholesterol regulate the interactions of Alzheimer's disease amyloid-beta peptide with membrane lipid.
The Journal of biological chemistry 2003;278(5):2977-82.
2002: Victoria Lewis; Alison Boyd; Colin L Masters; Steven J Collins
Apparently sporadic CJD and covert health-care transmissions.
Lancet neurology 2002;1(8):470-1.
2002: Zeinab Khalil; Helen Poliviou; Christa Maynard; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Abeta protein.
Journal of Alzheimer's disease : JAD 2002;4(6):467-78.
2002: Christa Maynard; Roberto Cappai; Irene Volitakis; Robert A Cherny; Anthony R White; Konrad Beyreuther; Colin L Masters; Ashley I Bush; Qiao-Xin Li
Overexpression of Alzheimer's disease amyloid-beta opposes the age-dependent elevations of brain copper and iron.
The Journal of biological chemistry 2002;277(47):44670-6.
2002: Steven Collins; Alison Boyd; James S Lee; Victoria Lewis; Ashley Fletcher; Catriona A McLean; M Law; John Kaldor; M J Smith; Colin L Masters
Creutzfeldt-Jakob disease in Australia 1970-1999.
Neurology 2002;59(9):1365-71.
2002: Carlos Opazo; Xudong Huang; Robert A Cherny; Robert D. Moir; Alex Roher; Anthony R White; Roberto Cappai; Colin L Masters; Rudolph E Tanzi; Nibaldo C Inestrosa; Ashley I Bush
Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).
The Journal of biological chemistry 2002;277(43):40302-8.
2002: Steven J Collins; Victoria Lewis; Marcus Brazier; Andrew Hill; Ashley Fletcher; Colin L Masters
Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model.
Annals of neurology 2002;52(4):503-6.
2002: Per Westermark; Merrill D Benson; Joel N Buxbaum; Alan S Cohen; Blas Frangione; Shu-ichi Ikeda; Colin L Masters; Giampaolo Merlini; Maria J Saraiva; Jean D Sipe
Amyloid fibril protein nomenclature -- 2002.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2002;9(3):197-200.
2002: A H Tammer; G Coia; Roberto Cappai; S Fuller; Colin L Masters; P Hudson; J R Underwood
Generation of a recombinant Fab antibody reactive with the Alzheimer's disease-related Abeta peptide.
Clinical and experimental immunology 2002;129(3):453-63.
2002: Qiao-Xin Li; Bruce C V Campbell; Catriona A McLean; Dominic Thyagarajan; Wei Ping Gai; Robert Kapsa; Konrad Beyreuther; Colin L Masters; Janetta G Culvenor
Platelet alpha- and gamma-synucleins in Parkinson's disease and normal control subjects.
Journal of Alzheimer's disease : JAD 2002;4(4):309-15.
2002: Andreas Simons; Thomas Ruppert; Carsten Schmidt; Andrea Schlicksupp; Rüdiger Pipkorn; Jennifer Reed; Colin L Masters; Anthony R White; Roberto Cappai; Konrad Beyreuther; Thomas A Bayer; Gerd Multhaup
Evidence for a copper-binding superfamily of the amyloid precursor protein.
Biochemistry 2002;41(30):9310-20.
2002: Janetta G Culvenor; Rodney L Rietze; Perry F Bartlett; Colin L Masters; Qiao-Xin Li
Oligodendrocytes from neural stem cells express alpha-synuclein: increased numbers from presenilin 1 deficient mice.
Neuroreport 2002;13(10):1305-8.
2002: Steven Collins; Alison Boyd; Ashley Fletcher; John Kaldor; Andrew Hill; Stephen Farish; Catriona McLean; Zahid Ansari; Margaret Smith; Colin L Masters
Creutzfeldt-Jakob disease cluster in an Australian rural city.
Annals of neurology 2002;52(1):115-8.
2002: Linda Truong; T Ng; M Rodriguez; A Harding; P Blumbergs; W Evans; V Fabian; J Fryer; M Gonzales; C Harper; R Kalnins; Colin L Masters; C McLean; D G Milder; R Pamphlett; G Scott; A Tannenberg; Jillian J Kril
Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria.
Acta neuropathologica 2002;104(1):72-8.
2002: John A Hamilton; Genevieve A Whitty; Anthony R White; Michael F Jobling; Andrew Thompson; Colin J Barrow; Roberto Cappai; Konrad Beyreuther; Colin L Masters
Alzheimer's disease amyloid beta and prion protein amyloidogenic peptides promote macrophage survival, DNA synthesis and enhanced proliferative response to CSF-1 (M-CSF).
Brain research 2002;940(1-2):49-54.
2002: R. M. Damian Holsinger; Catriona A McLean; Konrad Beyreuther; Colin L Masters; Geneviève Evin
Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease.
Annals of neurology 2002;51(6):783-6.
2002: Su San Mok; Bradley J Turner; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
Toxicity of substrate-bound amyloid peptides on vascular smooth muscle cells is enhanced by homocysteine.
European journal of biochemistry / FEBS 2002;269(12):3014-22.
2002: Geneviève Evin; Margaret J Smith; Angela Tziotis; Catriona McLean; Louise Canterford; Robyn A Sharples; Roberto Cappai; Andreas Weidemann; Konrad Beyreuther; Richard G H Cotton; Colin L Masters; Janetta G Culvenor
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(6):917-21.
2002: Lisa R Fodero; Javier Sáez-Valero; Catriona A McLean; Ralph N Martins; Konrad Beyreuther; Colin L Masters; Terry A Robertson; David Small
Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.
Journal of neurochemistry 2002;81(3):441-8.
2002: Geneviève Evin; Margaret J Smith; Angela Tziotis; Catriona McLean; Louise Canterford; Robyn A Sharples; Roberto Cappai; Andreas Weidemann; Konrad Beyreuther; Richard G H Cotton; Colin L Masters; Janetta G Culvenor
Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Neuroreport 2002;13(5):719-23.
2002: Alessandro Filla; Giuseppe De Michele; Sergio Cocozza; A Patrignani; Giampiero Volpe; Imma Castaldo; G Ruggiero; Vincenzo Bonavita; Colin L Masters; Giorgio Casari; Amalia C Bruni
Early onset autosomal dominant dementia with ataxia, extrapyramidal features, and epilepsy.
Neurology 2002;58(6):922-8.
2002: Andreas Weidemann; Simone Eggert; Friedrich B M Reinhard; Markus Vogel; Krzysztof Paliga; Gottfried Baier; Colin L Masters; Konrad Beyreuther; Geneviève Evin
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing.
Biochemistry 2002;41(8):2825-35.
2002: Stefan F Lichtenthaler; Dirk Beher; Heike S Grimm; Rong Wang; Mark S Shearman; Colin L Masters; Konrad Beyreuther
The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1365-70.
2002: Anthony R White; Gerd Multhaup; Denise Galatis; William J McKinstry; Michael W Parker; Rüdiger Pipkorn; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(2):365-76.
2002: Simon Laws; Eugene Hone; Kevin Taddei; C Harper; B Dean; Catriona McClean; Colin L Masters; Nicola T Lautenschlager; Sam Gandy; Ralph N Martins
Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein E.
Molecular psychiatry 2002;7(8):886-90.
2001: S W Chan; S Collins; Colin L Masters; D M Walker
Classical and variant Creutzfeldt-Jakob diseases and their potential impact on the practice of clinical dentistry in Australia.
Australian dental journal 2001;46(4):251-7.
2001: Dirk Beher; Jonathan D J Wrigley; Alan Nadin; Geneviève Evin; Colin L Masters; Timothy Harrison; José L Castro; Mark S Shearman
Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology.
The Journal of biological chemistry 2001;276(48):45394-402.
2001: Alison Boyd; Ashley Fletcher; James S Lee; Victoria Lewis; Colin L Masters; Steven J Collins
Transmissible spongiform encephalopathies in Australia.
Communicable diseases intelligence quarterly report 2001;25(4):248-52.
2001: Janelle Nunan; Mark S Shearman; F Checler; Roberto Cappai; Geneviève Evin; Konrad Beyreuther; Colin L Masters; David Small
The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase.
European journal of biochemistry / FEBS 2001;268(20):5329-36.
2001: Leanne R Stewart; Anthony R White; Michael F Jobling; B Elise Needham; Fran Maher; James Thyer; Konrad Beyreuther; Colin L Masters; Steven J Collins; Roberto Cappai
Involvement of the 5-lipoxygenase pathway in the neurotoxicity of the prion peptide PrP106-126.
Journal of neuroscience research 2001;65(6):565-72.
2001: Steven Collins; Catriona A McLean; Colin L Masters
Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(5):387-97.
2001: Geneviève Evin; Robyn A Sharples; Andreas Weidemann; Friedrich B M Reinhard; V Carbone; Janetta G Culvenor; R. M. Damian Holsinger; M Fleur Sernee; Konrad Beyreuther; Colin L Masters
Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease.
Biochemistry 2001;40(28):8359-68.
2001: Michael F Jobling; Xudong Huang; Leanne R Stewart; Kevin J Barnham; Cyril C Curtain; Irene Volitakis; Matthew A Perugini; Anthony R White; Robert A Cherny; Colin L Masters; Colin J Barrow; Steven J Collins; Ashley I Bush; Roberto Cappai
Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.
Biochemistry 2001;40(27):8073-84.
2001: Alexander Collie; Paul Maruff; Ruxsana Shafiq-Antonacci; M Smith; M Hallup; P R Schofield; Colin L Masters; Jon Currie
Memory decline in healthy older people: implications for identifying mild cognitive impairment.
Neurology 2001;56(11):1533-8.
2001: Cyril C Curtain; F Ali; Irene Volitakis; Robert A Cherny; Raymond S Norton; Konrad Beyreuther; Colin J Barrow; Colin L Masters; Ashley I Bush; Kevin J Barnham
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits.
The Journal of biological chemistry 2001;276(23):20466-73.
2001: K Fassbender; Colin L Masters; Konrad Beyreuther
Alzheimer's disease: molecular concepts and therapeutic targets.
Die Naturwissenschaften 2001;88(6):261-7.
2001: Robert A Cherny; Craig S Atwood; Michel E Xilinas; D N Gray; Walton D Jones; Catriona A McLean; Kevin J Barnham; Irene Volitakis; Fiona Fraser; Y Kim; Xudong Huang; Lee E Goldstein; Robert D. Moir; JT Lim; Konrad Beyreuther; Hui Zheng; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Neuron 2001;30(3):665-76.
2001: U L Jayasena; S K Gribble; A McKenzie; Konrad Beyreuther; Colin L Masters; J R Underwood
Identification of structural variations in the carboxyl terminus of Alzheimer's disease-associated beta A4[1-42] amyloid using a monoclonal antibody.
Clinical and experimental immunology 2001;124(2):297-305.
2001: Colin L Masters; Konrad Beyreuther
The Worster-Drought syndrome and other syndromes of dementia with spastic paraparesis: the paradox of molecular pathology.
Journal of neuropathology and experimental neurology 2001;60(4):317-9.
2001: Anthony R White; R Guirguis; Marcus Brazier; Michael F Jobling; Andrew Hill; Konrad Beyreuther; Colin J Barrow; Colin L Masters; Steven J Collins; Roberto Cappai
Sublethal concentrations of prion peptide PrP106-126 or the amyloid beta peptide of Alzheimer's disease activates expression of proapoptotic markers in primary cortical neurons.
Neurobiology of disease 2001;8(2):299-316.
2001: Anthony R White; Xudong Huang; Michael F Jobling; Colin J Barrow; Konrad Beyreuther; Colin L Masters; Ashley I Bush; Roberto Cappai
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways.
Journal of neurochemistry 2001;76(5):1509-20.
2001: Colin L Masters
The emerging European epidemic of variant Creutzfeldt-Jakob disease and bovine spongiform encephalopathy: lessons for Australia.
The Medical journal of Australia 2001;174(4):160-1.
2001: M J Smith; John B J Kwok; Catriona A McLean; Jillian J Kril; G Anthony Broe; G A Nicholson; Roberto Cappai; Marianne Hallupp; R G Cotton; Colin L Masters; Peter R Schofield; William S Brooks
Variable phenotype of Alzheimer's disease with spastic paraparesis.
Annals of neurology 2001;49(1):125-9.
2001: Bruce C V Campbell; Catriona A McLean; Janetta G Culvenor; Wei Ping Gai; Peter C Blumbergs; P Jäkälä; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease.
Journal of neurochemistry 2001;76(1):87-96.
2001: Marianna G Yakubovskaya; Anna A Neschastnova; KE Humphrey; jeffrey babon; Vladimir I Popenko; M J Smith; Andreana Lambrinakos; Z V Lipatova; M A Dobrovolskaia; Roberto Cappai; Colin L Masters; Gennady A Belitsky; Richard G H Cotton
Interaction of linear homologous DNA duplexes via Holliday junction formation.
European journal of biochemistry / FEBS 2001;268(1):7-14.
2000: A Thompson; Anthony R White; C McLean; Colin L Masters; Roberto Cappai; Colin J Barrow
Amyloidogenicity and neurotoxicity of peptides corresponding to the helical regions of PrP(C).
Journal of neuroscience research 2000;62(2):293-301.
2000: Su San Mok; Andrew B Clippingdale; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
A beta peptides and calcium influence secretion of the amyloid protein precursor from chick sympathetic neurons in culture.
Journal of neuroscience research 2000;61(4):449-57.
2000: Steven Collins; Alison Boyd; Ashley Fletcher; KA Byron; C Harper; Catriona A McLean; Colin L Masters
Novel prion protein gene mutation in an octogenarian with Creutzfeldt-Jakob disease.
Archives of neurology 2000;57(7):1058-63.
2000: Robert A Cherny; Kevin J Barnham; T Lynch; Irene Volitakis; Qiao-Xin Li; Catriona A McLean; Gerd Multhaup; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Chelation and intercalation: complementary properties in a compound for the treatment of Alzheimer's disease.
Journal of structural biology 2000;130(2-3):209-16.
2000: Thilo Borchardt; C Schmidt; J Camarkis; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Differential effects of zinc on amyloid precursor protein (APP) processing in copper-resistant variants of cultured Chinese hamster ovary cells.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(4):785-95.
2000: Bruce C V Campbell; Qiao-Xin Li; Janetta G Culvenor; P Jäkälä; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Catriona A McLean
Accumulation of insoluble alpha-synuclein in dementia with Lewy bodies.
Neurobiology of disease 2000;7(3):192-200.
2000: K Fassbender; Colin L Masters; Konrad Beyreuther
Alzheimer's disease: an inflammatory disease?
Neurobiology of aging 2000;21(3):433-6; discussion 451-3.
2000: Steven Collins; Alison Boyd; Ashley Fletcher; Michael Gonzales; Catriona A McLean; KA Byron; Colin L Masters
Creutzfeldt-Jakob disease: diagnostic utility of 14-3-3 protein immunodetection in cerebrospinal fluid.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2000;7(3):203-8.
2000: Steven Collins; Alison Boyd; Ashley Fletcher; Michael F Gonzales; Catriona A McLean; Colin L Masters
Recent advances in the pre-mortem diagnosis of Creutzfeldt-Jakob disease.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2000;7(3):195-202.
2000: G Emilien; Konrad Beyreuther; Colin L Masters; Jean-Marie Maloteaux
Prospects for pharmacological intervention in Alzheimer disease.
Archives of neurology 2000;57(4):454-9.
2000: Janetta G Culvenor; Geneviève Evin; M A Cooney; H Wardan; Robyn A Sharples; Fran Maher; G Reed; A Diehlmann; Andreas Weidemann; Konrad Beyreuther; Colin L Masters
Presenilin 2 expression in neuronal cells: induction during differentiation of embryonic carcinoma cells.
Experimental cell research 2000;255(2):192-206.
2000: Margaret J Smith; KE Humphrey; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Richard G H Cotton
Correct heteroduplex formation for mutation detection analysis.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology 2000;5(1):67-73.
2000: RB Postuma; W He; Janelle Nunan; Konrad Beyreuther; Colin L Masters; Colin J Barrow; David Small
Substrate-bound beta-amyloid peptides inhibit cell adhesion and neurite outgrowth in primary neuronal cultures.
Journal of neurochemistry 2000;74(3):1122-30.
2000: Elizabeth J Coulson; K Paliga; Konrad Beyreuther; Colin L Masters
What the evolution of the amyloid protein precursor supergene family tells us about its function.
Neurochemistry international 2000;36(3):175-84.
2000: Geneviève Evin; D Le Brocque; Janetta G Culvenor; Denise Galatis; Andreas Weidemann; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Presenilin I expression in yeast lowers secretion of the amyloid precursor protein.
Neuroreport 2000;11(2):405-8.
2000: G Emilien; Jean-Marie Maloteaux; Konrad Beyreuther; Colin L Masters
Alzheimer disease: mouse models pave the way for therapeutic opportunities.
Archives of neurology 2000;57(2):176-81.
2000: John B J Kwok; Q X Li; Marianne Hallupp; S Whyte; D Ames; Konrad Beyreuther; Colin L Masters; Peter R Schofield
Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis.
Annals of neurology 2000;47(2):249-53.
2000: C Bergsdorf; Krzysztof Paliga; Sylvia Kreger; Colin L Masters; Konrad Beyreuther
Identification of cis-elements regulating exon 15 splicing of the amyloid precursor protein pre-mRNA.
The Journal of biological chemistry 2000;275(3):2046-56.
2000: A Weidemann; K Paliga; U Dürrwang; F Reinhard; D Zhang; R Sandbrink; G Evin; Colin L Masters; K Beyreuther
Interaction of the Presenilins with the Amyloid Precursor Protein (APP).
Methods in molecular medicine 2000;32():333-44.
2000: Colin L Masters; Konrad Beyreuther
Genomic neurology.
Archives of neurology 2000;57(1):53.
1999: Xudong Huang; Math P Cuajungco; Craig S Atwood; Mariana A Hartshorn; J D Tyndall; G R Hanson; K C Stokes; M Leopold; Gerd Multhaup; Lee E Goldstein; RC Scarpa; Aleister J Saunders; J Lim; Robert D. Moir; C Glabe; E F Bowden; Colin L Masters; D P Fairlie; Rudolph E Tanzi; Ashley I Bush
Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.
The Journal of biological chemistry 1999;274(52):37111-6.
1999: Catriona A McLean; Robert A Cherny; Fiona Fraser; Stephanie J Fuller; M J Smith; Konrad Beyreuther; Ashley I Bush; Colin L Masters
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease.
Annals of neurology 1999;46(6):860-6.
1999: Thilo Borchardt; James Camakaris; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Copper inhibits beta-amyloid production and stimulates the non-amyloidogenic pathway of amyloid-precursor-protein secretion.
The Biochemical journal 1999;344 Pt 2():461-7.
1999: M D Caswell; Su San Mok; A Henry; Roberto Cappai; G Klug; Konrad Beyreuther; Colin L Masters; David Small
The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons.
European journal of biochemistry / FEBS 1999;266(2):509-16.
1999: Joseline Ojaimi; Colin L Masters; K Opeskin; Penny McKelvie; Edward Byrne
Mitochondrial respiratory chain activity in the human brain as a function of age.
Mechanisms of ageing and development 1999;111(1):39-47.
1999: David Small; H L Clarris; T G Williamson; G Reed; Brian Key; Su San Mok; Konrad Beyreuther; Colin L Masters; V Nurcombe
Neurite-outgrowth regulating functions of the amyloid protein precursor of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 1999;1(4-5):275-85.
1999: T A Bayer; Roberto Cappai; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
It all sticks together--the APP-related family of proteins and Alzheimer's disease.
Molecular psychiatry 1999;4(6):524-8.
1999: Anthony R White; Steven J Collins; Fran Maher; Michael F Jobling; Leanne R Stewart; James Thyer; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity.
The American journal of pathology 1999;155(5):1723-30.
1999: Anthony R White; Gerd Multhaup; Fran Maher; Shayne A Bellingham; James Camakaris; Hui Zheng; Ashley I Bush; Konrad Beyreuther; Colin L Masters; Roberto Cappai
The Alzheimer's disease amyloid precursor protein modulates copper-induced toxicity and oxidative stress in primary neuronal cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(21):9170-9.
1999: Q X Li; Stephanie J Fuller; Konrad Beyreuther; Colin L Masters
The amyloid precursor protein of Alzheimer disease in human brain and blood.
Journal of leukocyte biology 1999;66(4):567-74.
1999: Janetta G Culvenor; Catriona A McLean; S Cutt; Bruce C V Campbell; Fran Maher; P Jäkälä; Tobias Hartmann; Konrad Beyreuther; Colin L Masters; Qiao-Xin Li
Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.
The American journal of pathology 1999;155(4):1173-81.
1999: Joseline Ojaimi; Colin L Masters; C McLean; K Opeskin; Penny McKelvie; Edward Byrne
Irregular distribution of cytochrome c oxidase protein subunits in aging and Alzheimer's disease.
Annals of neurology 1999;46(4):656-60.
1999: Michael F Jobling; Leanne R Stewart; Anthony R White; C McLean; Anna Friedhuber; Fran Maher; Konrad Beyreuther; Colin L Masters; Colin J Barrow; Steven J Collins; Roberto Cappai
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126.
Journal of neurochemistry 1999;73(4):1557-65.
1999: Anthony R White; R Reyes; Julian F B Mercer; James Camakaris; Hui Zheng; Ashley I Bush; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice.
Brain research 1999;842(2):439-44.
1999: Robert A Cherny; J T Legg; Catriona A McLean; D P Fairlie; Xudong Huang; Craig S Atwood; Konrad Beyreuther; Rudolph E Tanzi; Colin L Masters; Ashley I Bush
Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.
The Journal of biological chemistry 1999;274(33):23223-8.
1999: Graham R Christie; RE Markwell; Carol W Gray; L Smith; F Godfrey; F Mansfield; H Wadsworth; R King; M McLaughlin; D G Cooper; RV Ward; David R Howlett; Tobias Hartmann; S F Lichtenthaler; Konrad Beyreuther; J Underwood; S K Gribble; Roberto Cappai; Colin L Masters; A Tamaoka; R L Gardner; A Jennifer Rivett; EH Karran; D Allsop
Alzheimer's disease: correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome.
Journal of neurochemistry 1999;73(1):195-204.
1999: Stefan F Lichtenthaler; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
A novel substrate for analyzing Alzheimer's disease gamma-secretase.
FEBS letters 1999;453(3):288-92.
1999: Colin L Masters; Konrad Beyreuther
Amyloid Nomenclature Committee.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(2):151-2.
1999: Qiao-Xin Li; C Maynard; Roberto Cappai; Catriona A McLean; Robert A Cherny; T Lynch; Janetta G Culvenor; J Trevaskis; JE Tanner; K A Bailey; C Czech; Ashley I Bush; Konrad Beyreuther; Colin L Masters
Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice.
Journal of neurochemistry 1999;72(6):2479-87.
1999: A Diehlmann; N Ida; Sascha Weggen; J Grünberg; Christian Haass; Colin L Masters; Thomas A Bayer; Konrad Beyreuther
Analysis of presenilin 1 and presenilin 2 expression and processing by newly developed monoclonal antibodies.
Journal of neuroscience research 1999;56(4):405-19.
1999: Thomas A Bayer; P Jäkälä; Tobias Hartmann; L Havas; C McLean; Janetta G Culvenor; Qiao-Xin Li; Colin L Masters; Peter Falkai; Konrad Beyreuther
Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.
Neuroscience letters 1999;266(3):213-6.
1999: Anthony R White; Ashley I Bush; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione.
Journal of neurochemistry 1999;72(5):2092-8.
1999: E Storey; M Katz; Y Brickman; Konrad Beyreuther; Colin L Masters
Amyloid precursor protein of Alzheimer's disease: evidence for a stable, full-length, trans-membrane pool in primary neuronal cultures.
The European journal of neuroscience 1999;11(5):1779-88.
1999: Jamie Rossjohn; Roberto Cappai; Susanne C Feil; A Henry; William J McKinstry; Denise Galatis; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Michael W Parker
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein.
Nature structural biology 1999;6(4):327-31.
1999: Dirk Beher; C Elle; J Underwood; John B Davis; R Ward; EH Karran; Colin L Masters; Konrad Beyreuther; Gerd Multhaup
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain.
Journal of neurochemistry 1999;72(4):1564-73.
1999: Roberto Cappai; L Stewart; Michael F Jobling; James Thyer; Anthony R White; Konrad Beyreuther; Steven J Collins; Colin L Masters; Colin J Barrow
Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: implications for the mechanism of prion formation.
Biochemistry 1999;38(11):3280-4.
1999: Stefan F Lichtenthaler; Rong Wang; Heike S Grimm; S N Uljon; Colin L Masters; Konrad Beyreuther
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3053-8.
1999: P Westermark; S Araki; M D Benson; A S Cohen; Blas Frangione; Colin L Masters; M J Saraiva; J D Sipe; G Husby; R A Kyle; Dennis J Selkoe
Nomenclature of amyloid fibril proteins. Report from the meeting of the International Nomenclature Committee on Amyloidosis, August 8-9, 1998. Part 1.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1999;6(1):63-6.
1999: Steven Collins; M G Law; Ashley Fletcher; Alison Boyd; John Kaldor; Colin L Masters
Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study.
Lancet 1999;353(9154):693-7.
1999: Andreas Weidemann; Krzysztof Paliga; U Dürrwang; Friedrich B M Reinhard; O Schuckert; Geneviève Evin; Colin L Masters
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases.
The Journal of biological chemistry 1999;274(9):5823-9.
1999: Margaret J Smith; R J McKinlay Gardner; Melanie A Knight; Susan M Forrest; Konrad Beyreuther; Elsdon Storey; Catriona A McLean; Richard G H Cotton; R Cappal; Colin L Masters
Early-onset Alzheimer's disease caused by a novel mutation at codon 219 of the presenilin-1 gene.
Neuroreport 1999;10(3):503-7.
1999: Roberto Cappai; Su San Mok; Denise Galatis; David Tucker; A Henry; Konrad Beyreuther; David Small; Colin L Masters
Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth.
FEBS letters 1999;442(1):95-8.
1999: Gerd Multhaup; Colin L Masters
Metal binding and radical generation of proteins in human neurological diseases and aging.
Metal ions in biological systems 1999;36():365-87.
1999: Gerd Multhaup; L Hesse; Thilo Borchardt; Thomas Ruppert; Roberto Cappai; Colin L Masters; Konrad Beyreuther
Autoxidation of amyloid precursor protein and formation of reactive oxygen species.
Advances in experimental medicine and biology 1999;448():183-92.
1998: A Fossgreen; B Brückner; C Czech; Colin L Masters; Konrad Beyreuther; Renato Paro
Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13703-8.
1998: A Henry; Qiao-Xin Li; Denise Galatis; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Inhibition of platelet activation by the Alzheimer's disease amyloid precursor protein.
British journal of haematology 1998;103(2):402-15.
1998: D Le Brocque; A Henry; Roberto Cappai; Qiao-Xin Li; JE Tanner; Denise Galatis; C Gray; S Holmes; JR Underwood; Konrad Beyreuther; Colin L Masters; Geneviève Evin
Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
Biochemistry 1998;37(42):14958-65.
1998: Kevin Taddei; John B J Kwok; Jillian J Kril; Linda Truong; Helen Creasey; Marianne Hallupp; C Fisher; William S Brooks; C Chung; C Andrews; Colin L Masters; Peter R Schofield; Ralph N Martins
Two novel presenilin-1 mutations (Ser169Leu and Pro436Gln) associated with very early onset Alzheimer's disease.
Neuroreport 1998;9(14):3335-9.
1998: Anthony R White; Hui Zheng; Denise Galatis; Fran Maher; L Hesse; Gerd Multhaup; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(16):6207-17.
1998: G Sberna; Javier Sáez-Valero; Qiao-Xin Li; C Czech; Konrad Beyreuther; Colin L Masters; Catriona A McLean; David Small
Acetylcholinesterase is increased in the brains of transgenic mice expressing the C-terminal fragment (CT100) of the beta-amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1998;71(2):723-31.
1998: Catriona A McLean; J W Ironside; M P Alpers; P W Brown; L Cervenakova; R M Anderson; Colin L Masters
Comparative neuropathology of Kuru with the new variant of Creutzfeldt-Jakob disease: evidence for strain of agent predominating over genotype of host.
Brain pathology (Zurich, Switzerland) 1998;8(3):429-37.
1998: Janetta G Culvenor; A Henry; Tobias Hartmann; Geneviève Evin; Denise Galatis; Anna Friedhuber; U L Jayasena; JR Underwood; Konrad Beyreuther; Colin L Masters; Roberto Cappai
Subcellular localization of the Alzheimer's disease amyloid precursor protein and derived polypeptides expressed in a recombinant yeast system.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 1998;5(2):79-89.
1998: RB Postuma; Ralph N Martins; Roberto Cappai; Konrad Beyreuther; Colin L Masters; Dudley K Strickland; Su San Mok; David Small
Effects of the amyloid protein precursor of Alzheimer's disease and other ligands of the LDL receptor-related protein on neurite outgrowth from sympathetic neurons in culture.
FEBS letters 1998;428(1-2):13-6.
1998: Gerd Multhaup; Thomas Ruppert; Andrea Schlicksupp; L Hesse; E Bill; Rüdiger Pipkorn; Colin L Masters; Konrad Beyreuther
Copper-binding amyloid precursor protein undergoes a site-specific fragmentation in the reduction of hydrogen peroxide.
Biochemistry 1998;37(20):7224-30.
1998: Kevin Taddei; Dun-Sheng Yang; C Fisher; Roger Clarnette; Joachim Hallmayer; R Barnetson; R Maller; William S Brooks; S Whyte; G A Nicholson; Colin L Masters; G Anthony Broe; Sam Gandy; Ralph N Martins
No association of presenilin-1 intronic polymorphism and Alzheimer's disease in Australia.
Neuroscience letters 1998;246(3):178-80.
1998: Qiao-Xin Li; S Whyte; JE Tanner; Geneviève Evin; Konrad Beyreuther; Colin L Masters
Secretion of Alzheimer's disease Abeta amyloid peptide by activated human platelets.
Laboratory investigation; a journal of technical methods and pathology 1998;78(4):461-9.
1998: Robert D. Moir; T Lynch; Ashley I Bush; S Whyte; A Henry; S Portbury; Gerd Multhaup; David Small; Rudolph E Tanzi; Konrad Beyreuther; Colin L Masters
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
The Journal of biological chemistry 1998;273(9):5013-9.
1998: Colin L Masters; Konrad Beyreuther
Alzheimer's disease.
BMJ (Clinical research ed.) 1998;316(7129):446-8.
1997: Stefan F Lichtenthaler; N Ida; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
Biochemistry 1997;36(49):15396-403.
1997: Krzysztof Paliga; G Peraus; Sylvia Kreger; U Dürrwang; L Hesse; Gerd Multhaup; Colin L Masters; Konrad Beyreuther; Andreas Weidemann
Human amyloid precursor-like protein 1--cDNA cloning, ectopic expression in COS-7 cells and identification of soluble forms in the cerebrospinal fluid.
European journal of biochemistry / FEBS 1997;250(2):354-63.
1997: Konrad Beyreuther; Colin L Masters
Alzheimer's disease. The ins and outs of amyloid-beta.
Nature 1997;389(6652):677-8.
1997: G C Peraus; Colin L Masters; Konrad Beyreuther
Late compartments of amyloid precursor protein transport in SY5Y cells are involved in beta-amyloid secretion.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(20):7714-24.
1997: Su San Mok; G Sberna; D Heffernan; Roberto Cappai; Denise Galatis; Heidi J Clarris; William H Sawyer; Konrad Beyreuther; Colin L Masters; David Small
Expression and analysis of heparin-binding regions of the amyloid precursor protein of Alzheimer's disease.
FEBS letters 1997;415(3):303-7.
1997: Elizabeth J Coulson; Graham L Barrett; Elsdon Storey; Perry F Bartlett; Konrad Beyreuther; Colin L Masters
Down-regulation of the amyloid protein precursor of Alzheimer's disease by antisense oligonucleotides reduces neuronal adhesion to specific substrata.
Brain research 1997;770(1-2):72-80.
1997: J Schröder; Johannes Pantel; N Ida; M Essig; Tobias Hartmann; M V Knopp; L R Schad; R Sandbrink; H Sauer; Colin L Masters; Konrad Beyreuther
Cerebral changes and cerebrospinal fluid beta-amyloid in Alzheimer's disease: a study with quantitative magnetic resonance imaging.
Molecular psychiatry 1997;2(6):505-7.
1997: Javier Sáez-Valero; G Sberna; C A McLean; Colin L Masters; David Small
Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.
Lancet 1997;350(9082):929.
1997: Janetta G Culvenor; Fran Maher; Geneviève Evin; F Malchiodi-Albedi; Roberto Cappai; JR Underwood; J B Davis; E H Karran; G W Roberts; Konrad Beyreuther; Colin L Masters
Alzheimer's disease-associated presenilin 1 in neuronal cells: evidence for localization to the endoplasmic reticulum-Golgi intermediate compartment.
Journal of neuroscience research 1997;49(6):719-31.
1997: Gerd Multhaup; Thomas Ruppert; Andrea Schlicksupp; L Hesse; Dirk Beher; Colin L Masters; Konrad Beyreuther
Reactive oxygen species and Alzheimer's disease.
Biochemical pharmacology 1997;54(5):533-9.
1997: Tobias Hartmann; S C Bieger; Barbara Brühl; P J Tienari; N Ida; D Allsop; G W Roberts; Colin L Masters; C G Dotti; Klaus Unsicker; Konrad Beyreuther
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides.
Nature medicine 1997;3(9):1016-20.
1997: G Sberna; Javier Sáez-Valero; Konrad Beyreuther; Colin L Masters; David Small
The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells.
Journal of neurochemistry 1997;69(3):1177-84.
1997: Colin L Masters; Konrad Beyreuther
Spongiform encephalopathies. Tracking turncoat prion proteins.
Nature 1997;388(6639):228-9.
1997: Catriona A McLean; Konrad Beyreuther; Colin L Masters
Commentary on the consensus recommendations for the post mortem diagnosis of Alzheimer's disease.
Neurobiology of aging 1997;18(4 Suppl):S89-90.
1997: A Henry; Colin L Masters; Konrad Beyreuther; Roberto Cappai
Expression of human amyloid precursor protein ectodomains in Pichia pastoris: analysis of culture conditions, purification, and characterization.
Protein expression and purification 1997;10(2):283-91.
1997: Konrad Beyreuther; Colin L Masters
Serpents on the road to dementia and death. Accumulating evidence from several studies points to the normal function of presenilin 1 and suggests how the mutant protein contributes to deposition of amyloid plaques in Alzheimer's disease.
Nature medicine 1997;3(7):723-5.
1997: C A McLean; Colin L Masters; V A Vladimirtsev; I A Prokhorova; Lev G Goldfarb; D M Asher; A I Vladimirtsev; Vasili P Alekseev; D Carleton Gajdusek
Viliuisk encephalomyelitis--review of the spectrum of pathological changes.
Neuropathology and applied neurobiology 1997;23(3):212-7.
1997: P J Tienari; N Ida; E Ikonen; M Simons; Andreas Weidemann; Gerd Multhaup; Colin L Masters; C G Dotti; Konrad Beyreuther
Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4125-30.
1997: Andreas Weidemann; Krzysztof Paliga; U Dürrwang; C Czech; Geneviève Evin; Colin L Masters; Konrad Beyreuther
Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein.
Nature medicine 1997;3(3):328-32.
1997: Heidi J Clarris; Roberto Cappai; D Heffernan; Konrad Beyreuther; Colin L Masters; David Small
Identification of heparin-binding domains in the amyloid precursor protein of Alzheimer's disease by deletion mutagenesis and peptide mapping.
Journal of neurochemistry 1997;68(3):1164-72.
1997: Su San Mok; Geneviève Evin; Qiao-Xin Li; A I Smith; Konrad Beyreuther; Colin L Masters; David Small
A novel metalloprotease in rat brain cleaves the amyloid precursor protein of Alzheimer's disease generating amyloidogenic fragments.
Biochemistry 1997;36(1):156-63.
1997: S Whyte; N Wilson; Jon Currie; Paul Maruff; V Malone; Ruxsana Shafiq-Antonacci; P Tyler; K L Derry; J Underwood; Q X Li; Konrad Beyreuther; Colin L Masters
Collection and normal levels of the amyloid precursor protein in plasma.
Annals of neurology 1997;41(1):121-4.
1997: R Sandbrink; U Mönning; Colin L Masters; Konrad Beyreuther
Expression of the APP gene family in brain cells, brain development and aging.
Gerontology 1997;43(1-2):119-31.
1996: T G Williamson; Su San Mok; A Henry; Roberto Cappai; A D Lander; V Nurcombe; Konrad Beyreuther; Colin L Masters; David Small
Secreted glypican binds to the amyloid precursor protein of Alzheimer's disease (APP) and inhibits APP-induced neurite outgrowth.
The Journal of biological chemistry 1996;271(49):31215-21.
1996: Robert Kapsa; M J Bernadette Jean-Francois; P Lertrit; S Weng; N Siregar; Joseline Ojaimi; G Donnan; Colin L Masters; Edward Byrne
Mitochondrial DNA polymorphism in substantia nigra.
Journal of the neurological sciences 1996;144(1-2):204-11.
1996: Konrad Beyreuther; Colin L Masters
Alzheimer's disease. Tangle disentanglement.
Nature 1996;383(6600):476-7.
1996: E Storey; Konrad Beyreuther; Colin L Masters
Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components.
Brain research 1996;735(2):217-31.
1996: P J Tienari; Bart De Strooper; E Ikonen; M Simons; Andreas Weidemann; C Czech; Tobias Hartmann; N Ida; Gerd Multhaup; Colin L Masters; Fred Van Leuven; Konrad Beyreuther; Carlos G Dotti
The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein.
The EMBO journal 1996;15(19):5218-29.
1996: E Storey; Timothy P Spurck; Jeremy D Pickett-Heaps; Konrad Beyreuther; Colin L Masters
The amyloid precursor protein of Alzheimer's disease is found on the surface of static but not activity motile portions of neurites.
Brain research 1996;735(1):59-66.
1996: N Ida; Colin L Masters; Konrad Beyreuther
Rapid cellular uptake of Alzheimer amyloid betaA4 peptide by cultured human neuroblastoma cells.
FEBS letters 1996;394(2):174-8.
1996: N Ida; Tobias Hartmann; Johannes Pantel; Johannes Schröder; R Zerfass; hans förstl; R Sandbrink; Colin L Masters; Konrad Beyreuther
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.
The Journal of biological chemistry 1996;271(37):22908-14.
1996: R Sandbrink; D Zhang; S Schaeffer; Colin L Masters; J Bauer; hans förstl; Konrad Beyreuther
Missense mutations of the PS-1/S182 gene in German early-onset Alzheimer's disease patients.
Annals of neurology 1996;40(2):265-6.
1996: Colin L Masters
Emergence of a new variant of Creutzfeldt-Jakob disease in Europe?
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(3):203-4.
1996: Tobias Hartmann; C Bergsdorf; R Sandbrink; P J Tienari; Gerd Multhaup; N Ida; S Bieger; T Dyrks; Andreas Weidemann; Colin L Masters; Konrad Beyreuther
Alzheimer's disease betaA4 protein release and amyloid precursor protein sorting are regulated by alternative splicing.
The Journal of biological chemistry 1996;271(22):13208-14.
1996: S Collins; Colin L Masters
Iatrogenic and zoonotic Creutzfeldt-Jakob disease: the Australian perspective.
The Medical journal of Australia 1996;164(10):598-602.
1996: D A Simpson; Colin L Masters; G Ohlrich; G Purdie; G Stuart; A E Tannenberg
Iatrogenic Creutzfeldt-Jakob disease and its neurosurgical implications.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(2):118-23.
1996: Steven J Collins; Roberto Cappai; Colin L Masters
Recent developments in the transmissible spongiform encephalopathies: Implications for clinical practice.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1996;3(2):97-101.
1996: Gerd Multhaup; Andrea Schlicksupp; L Hesse; Dirk Beher; T Ruppert; Colin L Masters; Konrad Beyreuther
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
Science (New York, N.Y.) 1996;271(5254):1406-9.
1996: R Sandbrink; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
Genes contributing to Alzheimer's disease.
Molecular psychiatry 1996;1(1):27-40.
1996: Dirk Beher; L Hesse; Colin L Masters; Gerd Multhaup
Regulation of amyloid protein precursor (APP) binding to collagen and mapping of the binding sites on APP and collagen type I.
The Journal of biological chemistry 1996;271(3):1613-20.
1996: Konrad Beyreuther; Gerd Multhaup; U Mönning; R Sandbrink; Dirk Beher; L Hesse; David Small; Colin L Masters
Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines.
Annals of the New York Academy of Sciences 1996;777():74-6.
1996: David Small; T Williamson; G Reed; Heidi J Clarris; Konrad Beyreuther; Colin L Masters; V Nurcombe
The role of heparan sulfate proteoglycans in the pathogenesis of Alzheimer's disease.
Annals of the New York Academy of Sciences 1996;777():316-21.
1996: R Sandbrink; Colin L Masters; Konrad Beyreuther
APP gene family. Alternative splicing generates functionally related isoforms.
Annals of the New York Academy of Sciences 1996;777():281-7.
1996: P J Tienari; Bart De Strooper; E Ikonen; N Ida; M Simons; Colin L Masters; Carlos G Dotti; Konrad Beyreuther
Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease.
Cold Spring Harbor symposia on quantitative biology 1996;61():575-85.
1996: Konrad Beyreuther; Gerd Multhaup; Colin L Masters
Alzheimer's disease: genesis of amyloid.
Ciba Foundation symposium 1996;199():119-27; discussion 127-31.
1995: R N LePage; Amanda J Fosang; S J Fuller; G Murphy; Geneviève Evin; Konrad Beyreuther; Colin L Masters; David Small
Gelatinase A possesses a beta-secretase-like activity in cleaving the amyloid protein precursor of Alzheimer's disease.
FEBS letters 1995;377(2):267-70.
1995: T G Williamson; V Nurcombe; Konrad Beyreuther; Colin L Masters; David Small
Affinity purification of proteoglycans that bind to the amyloid protein precursor of Alzheimer's disease.
Journal of neurochemistry 1995;65(5):2201-8.
1995: Geneviève Evin; Roberto Cappai; Qiao-Xin Li; Janetta G Culvenor; David Small; Konrad Beyreuther; Colin L Masters
Candidate gamma-secretases in the generation of the carboxyl terminus of the Alzheimer's disease beta A4 amyloid: possible involvement of cathepsin D.
Biochemistry 1995;34(43):14185-92.
1995: Colin L Masters
Neurodegenerative diseases of the elderly.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 1995;2(4):283-4.
1995: Janetta G Culvenor; Anna Friedhuber; S J Fuller; Konrad Beyreuther; Colin L Masters
Expression of the amyloid precursor protein of Alzheimer's disease on the surface of transfected HeLa cells.
Experimental cell research 1995;220(2):474-81.
1995: E Storey; Colin L Masters
Amyloid, aluminium and the aetiology of Alzheimer's disease.
The Medical journal of Australia 1995;163(5):256-9.
1995: Heidi J Clarris; Brian Key; Konrad Beyreuther; Colin L Masters; David Small
Expression of the amyloid protein precursor of Alzheimer's disease in the developing rat olfactory system.
Brain research. Developmental brain research 1995;88(1):87-95.
1995: Gerd Multhaup; H Mechler; Colin L Masters
Characterization of the high affinity heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP) and its enhancement by zinc(II).
Journal of molecular recognition : JMR 1995;8(4):247-57.
1995: S J Fuller; E Storey; Qiao-Xin Li; A I Smith; Konrad Beyreuther; Colin L Masters
Intracellular production of beta A4 amyloid of Alzheimer's disease: modulation by phosphoramidon and lack of coupling to the secretion of the amyloid precursor protein.
Biochemistry 1995;34(25):8091-8.
1995: Qiao-Xin Li; Geneviève Evin; David Small; Gerd Multhaup; Konrad Beyreuther; Colin L Masters
Proteolytic processing of Alzheimer's disease beta A4 amyloid precursor protein in human platelets.
The Journal of biological chemistry 1995;270(23):14140-7.
1995: U Mönning; R Sandbrink; Andreas Weidemann; R B Banati; Colin L Masters; Konrad Beyreuther
Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells.
The Journal of biological chemistry 1995;270(13):7104-10.
1995: Geneviève Evin; Konrad Beyreuther; Colin L Masters
A synthetic substrate assay for the gamma-secretase of the beta-A4 amyloid of Alzheimer's disease.
Journal of peptide science : an official publication of the European Peptide Society 1995;1(2):132-9.
1995: Colin L Masters; Konrad Beyreuther
Molecular neuropathology of Alzheimer's disease.
Arzneimittel-Forschung 1995;45(3A):410-2.
1995: Konrad Beyreuther; Colin L Masters
Neurodegeneration and dementia. Alzheimer's disease as a model.
Arzneimittel-Forschung 1995;45(3A):347-50.
1995: J Beer; Colin L Masters; Konrad Beyreuther
Cells from peripheral tissues that exhibit high APP expression are characterized by their high membrane fusion activity.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration 1995;4(1):51-9.
1995: S J Collins; Colin L Masters
Transmissibility of Creutzfeldt-Jakob disease and related disorders.
Science progress 1995;78 ( Pt 3)():217-27.
1995: E P Richardson; Colin L Masters
The nosology of Creutzfeldt-Jakob disease and conditions related to the accumulation of PrPCJD in the nervous system.
Brain pathology (Zurich, Switzerland) 1995;5(1):33-41.
1994: Gerd Multhaup; Ashley I Bush; P Pollwein; Colin L Masters
Interaction between the zinc (II) and the heparin binding site of the Alzheimer's disease beta A4 amyloid precursor protein (APP).
FEBS letters 1994;355(2):151-4.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
APP gene family: unique age-associated changes in splicing of Alzheimer's betaA4-amyloid protein precursor.
Neurobiology of disease 1994;1(1-2):13-24.
1994: hans förstl; C Czech; H Sattel; C Geiger-Kabisch; C Besthorn; Spencer Kreger; U Mönning; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
[Apolipoprotein E and Alzheimer dementia. Personal results and brief literature review].
Der Nervenarzt 1994;65(11):780-6.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Complete nucleotide and deduced amino acid sequence of rat amyloid protein precursor-like protein 2 (APLP2/APPH): two amino acids length difference to human and murine homologues.
Biochimica et biophysica acta 1994;1219(1):167-70.
1994: Ashley I Bush; Warren H Pettingell; Gerd Multhaup; M d Paradis; J P Vonsattel; James Gusella; Konrad Beyreuther; Colin L Masters; Rudolph E Tanzi
Rapid induction of Alzheimer A beta amyloid formation by zinc.
Science (New York, N.Y.) 1994;265(5177):1464-7.
1994: Konrad Beyreuther; Colin L Masters
Neurobiology. Catching the culprit prion.
Nature 1994;370(6489):419-20.
1994: L Hesse; Dirk Beher; Colin L Masters; Gerd Multhaup
The beta A4 amyloid precursor protein binding to copper.
FEBS letters 1994;349(1):109-16.
1994: Qiao-Xin Li; M C Berndt; Ashley I Bush; B Rumble; I Mackenzie; Anna Friedhuber; Konrad Beyreuther; Colin L Masters
Membrane-associated forms of the beta A4 amyloid protein precursor of Alzheimer's disease in human platelet and brain: surface expression on the activated human platelet.
Blood 1994;84(1):133-42.
1994: Heidi J Clarris; V Nurcombe; David Small; Konrad Beyreuther; Colin L Masters
Secretion of nerve growth factor from septum stimulates neurite outgrowth and release of the amyloid protein precursor of Alzheimer's disease from hippocampal explants.
Journal of neuroscience research 1994;38(3):248-58.
1994: M S Godec; D M Asher; W E Kozachuk; Colin L Masters; J U Rubi; J A Payne; D J Rubi-Villa; E E Wagner; Stanley I Rapoport; Mark B Schapiro
Blood buffy coat from Alzheimer's disease patients and their relatives does not transmit spongiform encephalopathy to hamsters.
Neurology 1994;44(6):1111-5.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.
The Journal of biological chemistry 1994;269(19):14227-34.
1994: U Mönning; R Sandbrink; R B Banati; Colin L Masters; Konrad Beyreuther
Transforming growth factor beta mediates increase of mature transmembrane amyloid precursor protein in microglial cells.
FEBS letters 1994;342(3):267-72.
1994: David Small; V Nurcombe; G Reed; Heidi J Clarris; Robert D. Moir; Konrad Beyreuther; Colin L Masters
A heparin-binding domain in the amyloid protein precursor of Alzheimer's disease is involved in the regulation of neurite outgrowth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(4):2117-27.
1994: Colin L Masters; Konrad Beyreuther
Alzheimer's disease: a clearer definition of the genetic components.
The Medical journal of Australia 1994;160(5):243-4.
1994: R Sandbrink; Colin L Masters; Konrad Beyreuther
Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons.
The Journal of biological chemistry 1994;269(2):1510-7.
1994: C Czech; hans förstl; F Hentschel; U Mönning; C Besthorn; C Geiger-Kabisch; H Sattel; Colin L Masters; Konrad Beyreuther
Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change.
European archives of psychiatry and clinical neuroscience 1994;243(5):291-2.
1994: B O Osuntokun; A Ogunniyi; Effiong Akang; PU Aghadiuno; A Ilori; E A Bamgboye; Konrad Beyreuther; Colin L Masters
Beta A4-amyloid in the brains of non-demented Nigerian Africans.
Lancet 1994;343(8888):56.
1994: C Czech; Colin L Masters; Konrad Beyreuther
Alzheimer's disease and transgenic mice.
Journal of neural transmission. Supplementum 1994;44():219-30.
1993: C Hilbich; U Mönning; C Grund; Colin L Masters; Konrad Beyreuther
Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11.
The Journal of biological chemistry 1993;268(35):26571-7.
1993: W Schubert; Colin L Masters; Konrad Beyreuther
APP+ T lymphocytes selectively sorted to endomysial tubes in polymyositis displace NCAM-expressing muscle fibers.
European journal of cell biology 1993;62(2):333-42.
1993: C Czech; V Mönning; P J Tienari; Tobias Hartmann; Colin L Masters; Konrad Beyreuther; hans förstl
Apolipoprotein E-epsilon 4 allele and Alzheimer's disease.
Lancet 1993;342(8882):1309.
1993: M Dichgans; U Mönning; G König; R Sandbrink; Colin L Masters; Konrad Beyreuther
APP expression in primary neuronal cell cultures from P6 mice during in vitro differentiation.
Dementia (Basel, Switzerland) 1993;4(6):301-7.
1993: Konrad Beyreuther; P Pollwein; Gerd Multhaup; U Mönning; G König; T Dyrks; W Schubert; Colin L Masters
Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.
Annals of the New York Academy of Sciences 1993;695():91-102.
1993: R Sandbrink; R Banati; Colin L Masters; Konrad Beyreuther; G König
Expression of L-APP mRNA in brain cells.
Annals of the New York Academy of Sciences 1993;695():183-9.
1993: Ashley I Bush; Konrad Beyreuther; Colin L Masters
The beta A4 amyloid protein precursor in human circulation.
Annals of the New York Academy of Sciences 1993;695():175-82.
1993: David Small; V Nurcombe; Heidi J Clarris; Konrad Beyreuther; Colin L Masters
The role of extracellular matrix in the processing of the amyloid protein precursor of Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():169-74.
1993: Ashley I Bush; Gerd Multhaup; Robert D. Moir; T G Williamson; David Small; B Rumble; P Pollwein; Konrad Beyreuther; Colin L Masters
A novel zinc(II) binding site modulates the function of the beta A4 amyloid protein precursor of Alzheimer's disease.
The Journal of biological chemistry 1993;268(22):16109-12.
1993: T Dyrks; E Dyrks; Colin L Masters; Konrad Beyreuther
Amyloidogenicity of rodent and human beta A4 sequences.
FEBS letters 1993;324(2):231-6.
1993: Gerd Multhaup; Colin L Masters; Konrad Beyreuther
A molecular approach to Alzheimer's disease.
Biological chemistry Hoppe-Seyler 1993;374(1):1-8.
1993: Marla Gearing; R W Wilson; Elizabeth R Unger; Earl R Shelton; H W Chan; Colin L Masters; Konrad Beyreuther; Suzanne S Mirra
Amyloid precursor protein (APP) in the striatum in Alzheimer's disease: an immunohistochemical study.
Journal of neuropathology and experimental neurology 1993;52(1):22-30.
1992: U Mönning; G König; R B Banati; H Mechler; C Czech; J Gehrmann; U Schreiter-Gasser; Colin L Masters; Konrad Beyreuther
Alzheimer beta A4-amyloid protein precursor in immunocompetent cells.
The Journal of biological chemistry 1992;267(33):23950-6.
1992: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Substitutions of hydrophobic amino acids reduce the amyloidogenicity of Alzheimer's disease beta A4 peptides.
Journal of molecular biology 1992;228(2):460-73.
1992: David Small; V Nurcombe; Robert D. Moir; S Michaelson; D Monard; Konrad Beyreuther; Colin L Masters
Association and release of the amyloid protein precursor of Alzheimer's disease from chick brain extracellular matrix.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(11):4143-50.
1992: Robert D. Moir; Ralph N Martins; Ashley I Bush; David Small; E A Milward; B A Rumble; Gerd Multhaup; Konrad Beyreuther; Colin L Masters
Human brain beta A4 amyloid protein precursor of Alzheimer's disease: purification and partial characterization.
Journal of neurochemistry 1992;59(4):1490-8.
1992: T Dyrks; E Dyrks; Tobias Hartmann; Colin L Masters; Konrad Beyreuther
Amyloidogenicity of beta A4 and beta A4-bearing amyloid protein precursor fragments by metal-catalyzed oxidation.
The Journal of biological chemistry 1992;267(25):18210-7.
1992: T Dyrks; E Dyrks; Colin L Masters; Konrad Beyreuther
Membrane inserted APP fragments containing the beta A4 sequence of Alzheimer's disease do not aggregate.
FEBS letters 1992;309(1):20-4.
1992: E A Milward; R Papadopoulos; S J Fuller; Robert D. Moir; D Small; Konrad Beyreuther; Colin L Masters
The amyloid protein precursor of Alzheimer's disease is a mediator of the effects of nerve growth factor on neurite outgrowth.
Neuron 1992;9(1):129-37.
1992: G König; U Mönning; C Czech; R Prior; R Banati; U Schreiter-Gasser; J Bauer; Colin L Masters; Konrad Beyreuther
Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.
The Journal of biological chemistry 1992;267(15):10804-9.
1992: P Pollwein; Colin L Masters; Konrad Beyreuther
The expression of the amyloid precursor protein (APP) is regulated by two GC-elements in the promoter.
Nucleic acids research 1992;20(1):63-8.
1992: Konrad Beyreuther; T Dyrks; C Hilbich; U Mönning; G König; Gerd Multhaup; P Pollwein; Colin L Masters
Amyloid precursor protein (APP) and beta A4 amyloid in Alzheimer's disease and Down syndrome.
Progress in clinical and biological research 1992;379():159-82.
1992: Ashley I Bush; Konrad Beyreuther; Colin L Masters
Beta A4 amyloid protein and its precursor in Alzheimer's disease.
Pharmacology & therapeutics 1992;56(1):97-117.
1991: W Schubert; R Prior; Andreas Weidemann; Heinrich Dircksen; Gerd Multhaup; Colin L Masters; Konrad Beyreuther
Localization of Alzheimer beta A4 amyloid precursor protein at central and peripheral synaptic sites.
Brain research 1991;563(1-2):184-94.
1991: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Human and rodent sequence analogs of Alzheimer's amyloid beta A4 share similar properties and can be solubilized in buffers of pH 7.4.
European journal of biochemistry / FEBS 1991;201(1):61-9.
1991: M S Godec; D M Asher; Colin L Masters; W E Kozachuk; Robert P Friedland; CJ Gibbs; D Carleton Gajdusek; Stanley I Rapoport; Mark B Schapiro
Evidence against the transmissibility of Alzheimer's disease.
Neurology 1991;41(8):1320.
1991: Konrad Beyreuther; Colin L Masters
Amyloid precursor protein (APP) and beta A4 amyloid in the etiology of Alzheimer's disease: precursor-product relationships in the derangement of neuronal function.
Brain pathology (Zurich, Switzerland) 1991;1(4):241-51.
1991: Colin L Masters; Konrad Beyreuther
Alzheimer's disease: molecular basis of structural lesions.
Brain pathology (Zurich, Switzerland) 1991;1(4):226-7.
1991: J Bauer; G König; S Strauss; U Jonas; U Ganter; Andreas Weidemann; U Mönning; Colin L Masters; B Volk; M Berger
In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells.
FEBS letters 1991;282(2):335-40.
1991: Z Matkovic; S Davis; M Gonzales; R Kalnins; Colin L Masters
Surgical risk of hemorrhage in cerebral amyloid angiopathy.
Stroke; a journal of cerebral circulation 1991;22(4):456-61.
1991: P Le Coz; Jacqueline Mikol; J Ferrand; France Woimant; Colin L Masters; Konrad Beyreuther; M Haguenau; J Cophignon; B Pepin
Granulomatous angiitis and cerebral amyloid angiopathy presenting as a mass lesion.
Neuropathology and applied neurobiology 1991;17(2):149-55.
1991: R Prior; U Mönning; U Schreiter-Gasser; Andreas Weidemann; Kaj Blennow; Carl-Gerhard Gottfries; Colin L Masters; Konrad Beyreuther
Quantitative changes in the amyloid beta A4 precursor protein in Alzheimer cerebrospinal fluid.
Neuroscience letters 1991;124(1):69-73.
1991: C Hilbich; B Kisters-Woike; J Reed; Colin L Masters; Konrad Beyreuther
Aggregation and secondary structure of synthetic amyloid beta A4 peptides of Alzheimer's disease.
Journal of molecular biology 1991;218(1):149-63.
1991: Lee J Martin; Sangram S Sisodia; Edward H Koo; L C Cork; T L Dellovade; Andreas Weidemann; Konrad Beyreuther; Colin L Masters; Donald L Price
Amyloid precursor protein in aged nonhuman primates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1461-5.
1991: S J Richards; J J Waters; Konrad Beyreuther; Colin L Masters; C M Wischik; Dennis Sparkman; Charles L White; Carmela Abraham; Stephen B Dunnett
Transplants of mouse trisomy 16 hippocampus provide a model of Alzheimer's disease neuropathology.
The EMBO journal 1991;10(2):297-303.
1991: G König; J M Salbaum; O Wiestler; W Lang; H P Schmitt; Colin L Masters; Konrad Beyreuther
Alternative splicing of the beta A4 amyloid gene of Alzheimer's disease in cortex of control and Alzheimer's disease patients.
Brain research. Molecular brain research 1991;9(3):259-62.
1991: Jean-Jacques Martin; J Gheuens; M Bruyland; Patrick Cras; Antoon Vandenberghe; Colin L Masters; Konrad Beyreuther; R Dom; Chantal Ceuterick; Ursula Lübke
Early-onset Alzheimer's disease in 2 large Belgian families.
Neurology 1991;41(1):62-8.
1991: Ralph N Martins; P J Robinson; J O Chleboun; Konrad Beyreuther; Colin L Masters
The molecular pathology of amyloid deposition in Alzheimer's disease.
Molecular neurobiology 1991;5(2-4):389-98.
1990: U Mönning; G König; R Prior; H Mechler; U Schreiter-Gasser; Colin L Masters; Konrad Beyreuther
Synthesis and secretion of Alzheimer amyloid beta A4 precursor protein by stimulated human peripheral blood leucocytes.
FEBS letters 1990;277(1-2):261-6.
1990: L C Cork; Colin L Masters; Konrad Beyreuther; Donald L Price
Development of senile plaques. Relationships of neuronal abnormalities and amyloid deposits.
The American journal of pathology 1990;137(6):1383-92.
1990: K Sorimachi; David J Craik; E J Lloyd; Konrad Beyreuther; Colin L Masters
Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein.
Biochemistry international 1990;22(3):447-54.
1990: G König; Colin L Masters; Konrad Beyreuther
Retinoic acid induced differentiated neuroblastoma cells show increased expression of the beta A4 amyloid gene of Alzheimer's disease and an altered splicing pattern.
FEBS letters 1990;269(2):305-10.
1990: P Delaère; Charles Duyckaerts; Colin L Masters; Konrad Beyreuther; F Piette; JEAN-JACQUES HAUW
Large amounts of neocortical beta A4 deposits without neuritic plaques nor tangles in a psychometrically assessed, non-demented person.
Neuroscience letters 1990;116(1-2):87-93.
1990: Colin L Masters
About a peculiar disease. Interview by Gay Hudson.
The Australian nurses' journal 1990;20(1):12-4.
1990: N Catteruccia; J Willingale-Theune; D Bunke; R Prior; Colin L Masters; A Crisanti; Konrad Beyreuther
Ultrastructural localization of the putative precursors of the A4 amyloid protein associated with Alzheimer's disease.
The American journal of pathology 1990;137(1):19-26.
1990: W L Irving; D S Crimmins; Colin L Masters; A L Cunningham
Creutzfeldt-Jakob disease and slow infections: a review.
Australian and New Zealand journal of medicine 1990;20(3):283-90.
1990: B Dropulić; Colin L Masters
Entry of neurotropic arboviruses into the central nervous system: an in vitro study using mouse brain endothelium.
The Journal of infectious diseases 1990;161(4):685-91.
1990: Edward H Koo; Sangram S Sisodia; D R Archer; Lee J Martin; Andreas Weidemann; Konrad Beyreuther; P Fischer; Colin L Masters; Donald L Price
Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1561-5.
1990: Lary Walker; Colin L Masters; Konrad Beyreuther; Donald L Price
Amyloid in the brains of aged squirrel monkeys.
Acta neuropathologica 1990;80(4):381-7.
1990: S J Richards; J J Waters; D C Rogers; F L Martel; Dennis Sparkman; Charles L White; Konrad Beyreuther; Colin L Masters; Stephen B Dunnett
Hippocampal grafts derived from embryonic trisomy 16 mice exhibit amyloid (A4) and neurofibrillary pathology.
Progress in brain research 1990;82():215-23.
1990: Konrad Beyreuther; Colin L Masters
Nomenclature of amyloid A4 proteins and their precursors in Alzheimer's disease and Down's syndrome.
Neurobiology of aging 1990;11(1):66-8.
1990: Colin L Masters; Konrad Beyreuther
Protein abnormalities in neurofibrillary tangles: their relation to the extracellular amyloid deposits of the A4 protein in Alzheimer's disease.
Advances in neurology 1990;51():151-61.
1989: J M Rozemuller; Piet Eikelenboom; F C Stam; Konrad Beyreuther; Colin L Masters
A4 protein in Alzheimer's disease: primary and secondary cellular events in extracellular amyloid deposition.
Journal of neuropathology and experimental neurology 1989;48(6):674-91.
1989: Bernardino Ghetti; Fabrizio Tagliavini; Colin L Masters; Konrad Beyreuther; Giorgio Giaccone; L Verga; Martin R Farlow; P M Conneally; Stephen R Dlouhy; Biagio Azzarelli
Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family.
Neurology 1989;39(11):1453-61.
1989: Bradley T Hyman; Gary W Van Hoesen; Konrad Beyreuther; Colin L Masters
A4 amyloid protein immunoreactivity is present in Alzheimer's disease neurofibrillary tangles.
Neuroscience letters 1989;101(3):352-5.
1989: D M A Mann; A Brown; D Prinja; Christine Ann Davies; M Landon; Colin L Masters; K Beyreuthers
An analysis of the morphology of senile plaques in Down's syndrome patients of different ages using immunocytochemical and lectin histochemical techniques.
Neuropathology and applied neurobiology 1989;15(4):317-29.
1989: David Nochlin; Shuzo M Sumi; Thomas D Bird; AD Snow; C M Leventhal; Konrad Beyreuther; Colin L Masters
Familial dementia with PrP-positive amyloid plaques: a variant of Gerstmann-Sträussler syndrome.
Neurology 1989;39(7):910-8.
1989: B Rumble; R Retallack; C Hilbich; G Simms; Gerd Multhaup; Ralph N Martins; A Hockey; P Montgomery; Konrad Beyreuther; Colin L Masters
Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.
The New England journal of medicine 1989;320(22):1446-52.
1989: Andreas Weidemann; G König; D Bunke; P Fischer; J M Salbaum; Colin L Masters; Konrad Beyreuther
Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein.
Cell 1989;57(1):115-26.
1989: Colin L Masters
Creutzfeldt-Jakob disease: its origins.
Alzheimer disease and associated disorders 1989;3(1-2):46-51.
1989: F L Mastaglia; Colin L Masters; Konrad Beyreuther; B A Kakulas
Deposition of Alzheimer's disease amyloid (A4) protein in the cerebral cortex in Parkinson's disease.
Progress in clinical and biological research 1989;317():475-84.
1989: J M Salbaum; Andreas Weidemann; Colin L Masters; Konrad Beyreuther
The promoter of Alzheimer's disease amyloid A4 precursor gene.
Progress in clinical and biological research 1989;317():277-83.
1989: T Dyrks; G König; C Hilbich; Colin L Masters; Konrad Beyreuther
Molecular pathology of the amyloid A4 precursor of Alzheimer's disease.
Progress in clinical and biological research 1989;317():877-91.
1989: G König; Konrad Beyreuther; Colin L Masters; H P Schmitt; J M Salbaum
PreA4 mRNA distribution in brain areas.
Progress in clinical and biological research 1989;317():1027-36.
1989: Colin L Masters; Konrad Beyreuther
The pathology of the amyloid A4 precursor of Alzheimer's disease.
Annals of medicine 1989;21(2):89-90.
1988: L Davies; B Wolska; C Hilbich; Gerd Multhaup; Ralph N Martins; G Simms; Konrad Beyreuther; Colin L Masters
A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques.
Neurology 1988;38(11):1688-93.
1988: J M Salbaum; Andreas Weidemann; H G Lemaire; Colin L Masters; Konrad Beyreuther
The promoter of Alzheimer's disease amyloid A4 precursor gene.
The EMBO journal 1988;7(9):2807-13.
1988: T Dyrks; Andreas Weidemann; Gerd Multhaup; J M Salbaum; H G Lemaire; J Kang; Benno Müller-Hill; Colin L Masters; Konrad Beyreuther
Identification, transmembrane orientation and biogenesis of the amyloid A4 precursor of Alzheimer's disease.
The EMBO journal 1988;7(4):949-57.
1988: J M Papadimitriou; A Hockey; N Tan; Colin L Masters
Rett syndrome: abnormal membrane-bound lamellated inclusions in neurons and oligodendroglia.
American journal of medical genetics 1988;29(2):365-8.
1988: K Zimmermann; T Herget; J M Salbaum; W Schubert; C Hilbich; M Cramer; Colin L Masters; Gerd Multhaup; J Kang; H G Lemaire
Localization of the putative precursor of Alzheimer's disease-specific amyloid at nuclear envelopes of adult human muscle.
The EMBO journal 1988;7(2):367-72.
1988: Colin L Masters; Konrad Beyreuther
The blood-brain barrier in Alzheimer's disease and normal aging.
Neurobiology of aging 1988;9(1):43-4.
1988: Colin L Masters; Konrad Beyreuther
Neuropathology of unconventional virus infections: molecular pathology of spongiform change and amyloid plaque deposition.
Ciba Foundation symposium 1988;135():24-36.
1987: B Dropulić; Colin L Masters
Culture of mouse brain capillary endothelial cell lines that express factor VIII, gamma-glutamyl transpeptidase, and form junctional complexes in vitro.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1987;23(11):775-81.
1987: DON GUIROY; M Miyazaki; Gerd Multhaup; P Fischer; R M Garruto; Konrad Beyreuther; Colin L Masters; G Simms; CJ Gibbs; D Carleton Gajdusek
Amyloid of neurofibrillary tangles of Guamanian parkinsonism-dementia and Alzheimer disease share identical amino acid sequence.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(7):2073-7.
1987: J Kang; H G Lemaire; A Unterbeck; J M Salbaum; Colin L Masters; K H Grzeschik; Gerd Multhaup; Konrad Beyreuther; Benno Müller-Hill
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
Nature 1987;325(6106):733-6.
1987: Colin L Masters; Konrad Beyreuther
Neuronal origin of cerebral amyloidogenic proteins: their role in Alzheimer's disease and unconventional virus diseases of the nervous system.
Ciba Foundation symposium 1987;126():49-64.
1986: Colin L Masters; Konrad Beyreuther
The structure of amyloid filaments in Alzheimer's disease and the unconventional virus infections of the nervous system.
Psychological medicine 1986;16(4):735-7.
1986: Ralph N Martins; G B Stokes; Colin L Masters
Regulation of liver and brain hexose monophosphate dehydrogenases by insulin and dietary intake in the female rat.
Molecular and cellular biochemistry 1986;70(2):169-75.
1986: Ralph N Martins; Clive Harper; G B Stokes; Colin L Masters
Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress.
Journal of neurochemistry 1986;46(4):1042-5.
1986: Clive Harper; T J Day; Colin L Masters
Rapidly progressive dementia with ataxia.
The Medical journal of Australia 1986;144(1):24-6, 28.
1986: N Tan; B A Kakulas; Colin L Masters; D Carleton Gajdusek; R M Garruto; K M Chen; C J Gibbs
Observations on the clinical presentations and the neuropathological findings of amyotrophic lateral sclerosis in Australia and Guam.
Annals of the Academy of Medicine, Singapore 1986;15(1):62-6.
1985: Colin L Masters; Gerd Multhaup; G Simms; J Pottgiesser; Ralph N Martins; Konrad Beyreuther
Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.
The EMBO journal 1985;4(11):2757-63.
1985: Colin L Masters; G Simms; N A Weinman; Gerd Multhaup; B L McDonald; Konrad Beyreuther
Amyloid plaque core protein in Alzheimer disease and Down syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4245-9.
1985: Colin L Masters; B L McDonald; C Lagenauer; M Schachner; M C Franko
Loop arrays in mouse brain demonstrated with antisera to cytokeratins and monoclonal antibodies to several classes of intermediate filaments: strain differences and developmental expression.
Brain research 1985;334(2):267-79.
1985: Colin L Masters; P Jacobsen; B A Kakulas
Decontamination of formaldehyde-fixed cerebral tissues of Creutzfeldt-Jakob disease by autoclaving, without the loss of microscopic visual quality.
Journal of neuropathology and experimental neurology 1985;44(3):304-6.
1985: Colin L Masters
Perspectives on prions.
Nature 1985;314(6006):15-6.
1985: Ralph N Martins; G B Stokes; Colin L Masters
Regulation of the multiple molecular forms of rat liver glucose 6-phosphate dehydrogenase by insulin and dietary restriction.
Biochemical and biophysical research communications 1985;127(1):136-42.
1984: Colin L Masters
Etiology and pathogenesis of Alzheimer's disease.
Pathology 1984;16(3):233-4.
1984: Colin L Masters; Robert G Rohwer; M C Franko; P Brown; D Carleton Gajdusek
The sequential development of spongiform change and gliosis of scrapie in the golden Syrian hamster.
Journal of neuropathology and experimental neurology 1984;43(3):242-52.
1983: A M Salazar; Colin L Masters; D Carleton Gajdusek; C J Gibbs
Syndromes of amyotrophic lateral sclerosis and dementia: relation to transmissible Creutzfeldt-Jakob disease.
Annals of neurology 1983;14(1):17-26.
1983: E M Scrimgeour; Colin L Masters; M P Alpers; J Kaven; D C Gajusek
A clinico-pathological study of a case of kuru.
Journal of the neurological sciences 1983;59(2):265-75.
1983: M Schachner; I Sommer; C Lagenaur; Colin L Masters
Glial antigens C1 and M1 in normal and abnormal development and after injury.
Birth defects original article series 1983;19(4):315-25.
1983: P A Merz; Henryk M Wisniewski; R A Somerville; S A Bobin; Colin L Masters; Khalid Iqbal
Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques.
Acta neuropathologica 1983;60(1-2):113-24.
1983: D M Asher; Colin L Masters; D Carleton Gajdusek; C J Gibbs
Familial spongiform encephalopathies.
Research publications - Association for Research in Nervous and Mental Disease 1983;60():273-91.
1982: M C Moreau-Dubois; P Brown; Robert G Rohwer; Colin L Masters; M Franko; D Carleton Gajdusek
Experimental scrapie in golden Syrian hamsters: temporal comparison of in vitro cell-fusing activity with brain infectivity and histopathological changes.
Infection and immunity 1982;37(1):195-9.
1982: P Nyberg; B G Almay; Arvid Carlsson; Colin L Masters; Bengt Winblad
Brain monoamine abnormalities in the two types of Creutzfeldt-Jakob disease.
Acta neurologica Scandinavica 1982;66(1):16-24.
1982: C Lagenaur; Colin L Masters; M Schachner
Changes in expression of glial antigens M1 and C1 after cerebellar injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1982;2(4):470-6.
1981: M C Franko; Colin L Masters; C J Gibbs; D Carleton Gajdusek
Monoclonal antibodies to central nervous system antigens.
Journal of neuroimmunology 1981;1(4):391-411.
1981: J Monreal; G H Collins; Colin L Masters; C M Fisher; R C Kim; C J Gibbs; D Carleton Gajdusek
Creutzfeldt-Jakob disease in an adolescent.
Journal of the neurological sciences 1981;52(2-3):341-50.
1981: Colin L Masters; D Carleton Gajdusek; C J Gibbs
The familial occurrence of Creutzfeldt-Jakob disease and Alzheimer's disease.
Brain : a journal of neurology 1981;104(3):535-58.
1981: Colin L Masters; D Carleton Gajdusek; C J Gibbs
Creutzfeldt-Jakob disease virus isolations from the Gerstmann-Sträussler syndrome with an analysis of the various forms of amyloid plaque deposition in the virus-induced spongiform encephalopathies.
Brain : a journal of neurology 1981;104(3):559-88.
1981: W C Schoene; Colin L Masters; C J Gibbs; D Carleton Gajdusek; H R Tyler; F D Moore; G J Dammin
Transmissible spongiform encephalopathy (Creutzfeldt-Jakob disease). Atypical clinical and pathological findings.
Archives of neurology 1981;38(8):473-7.
1981: D M Landis; R S Williams; Colin L Masters
Golgi and electronmicroscopic studies of spongiform encephalopathy.
Neurology 1981;31(5):538-49.
1981: N T Tan; B A Kakulas; Colin L Masters; K M Chen; C J Gibbs; D Carleton Gajdusek
Neuropathology of the cortical lesions of the Parkinsonian-dementia (PD) complex of Guam.
Clinical and experimental neurology 1981;17():227-34.
1980: J Goudsmit; C H Morrow; D M Asher; R T Yanagihara; Colin L Masters; C J Gibbs; D Carleton Gajdusek
Evidence for and against the transmissibility of Alzheimer disease.
Neurology 1980;30(9):945-50.
1980: CJ Gibbs; H L Amyx; A Bacote; Colin L Masters; D Carleton Gajdusek
Oral transmission of kuru, Creutzfeldt-Jakob disease, and scrapie to nonhuman primates.
The Journal of infectious diseases 1980;142(2):205-8.
1980: S Gálvez; D Carleton Gajdusek; Colin L Masters
[Experimental transmission of Creutzfeldt-Jakob disease to the guinea pig (author's transl)].
Revista médica de Chile 1980;108(4):299-303.
1980: J R Baringer; D Carleton Gajdusek; C J Gibbs; Colin L Masters; W E Stern; R D Terry
Transmissible dementias: current problems in tissue handling.
Neurology 1980;30(3):302-3.
1980: S Galvez; Colin L Masters; C Gajdusek
Descriptive epidemiology of Creutzfeldt-Jakob disease in Chile.
Archives of neurology 1980;37(1):11-4.
1979: Colin L Masters; J O Harris; D Carleton Gajdusek; C J Gibbs; C Bernoulli; D M Asher
Creutzfeldt-Jakob disease: patterns of worldwide occurrence and the significance of familial and sporadic clustering.
Annals of neurology 1979;5(2):177-88.
1978: Colin L Masters; E P Richardson
Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease). The nature and progression of spongiform change.
Brain : a journal of neurology 1978;101(2):333-44.
1978: Colin L Masters
Pathogenesis of the Arnold-Chiari malformation: the significance of hydrocephalus and aqueduct stenosis.
Journal of neuropathology and experimental neurology 1978;37(1):56-74.
1977: Colin L Masters; R L Dawkins; P J Zilko; J A Simpson; R J Leedman
Penicillamine-associated myasthenia gravis, antiacetylcholine receptor and antistriational antibodies.
The American journal of medicine 1977;63(5):689-94.
1977: A Hockey; Colin L Masters
Menkes' kinky (steely) hair disease.
The Australasian journal of dermatology 1977;18(2):77-80.
1976: Colin L Masters; B A Kakulas; M P Alpers; D Carleton Gajdusek; C J Gibbs
Preclinical lesions and their progression in the experimental spongiform encephalopathies (kuru and Creutzfeldt-Jakob disease) in primates.
Journal of neuropathology and experimental neurology 1976;35(6):593-605.
1976: Colin L Masters; M P Alpers; D Carleton Gajdusek; C J Gibbs; B A Kakulas
Experimental kuru in the gibbon and sooty mangabey and Creutzfeldt-Jakob disease in the pigtailed macaque. With a summary of the host range of the subacute spongiform virus encephalopathies.
Journal of medical primatology 1976;5(4):205-9.
1969: Colin L Masters; L P Bignold; E H Morgan
Plasma protein metabolism and transfer to the fetus during pregnancy in the rat.
The American journal of physiology 1969;216(4):876-83.