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Michael Mastrangelo

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TOP 3
Sara L Montgomery; Wade C Narrow; Terry W Wright; Diala Habib; Sara A Knowlden; Michael A Mastrangelo; William J Bowers
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
Suresh de Silva; Michael A Mastrangelo; Louis T Lotta; Clark A Burris; Zsuzsanna Izsvák; Zoltán Ivics; William J Bowers
Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo.
Maya K Desai; Michael A Mastrangelo; Deborah A Ryan; Kelly L Sudol; Wade C Narrow; William J Bowers
Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target.

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All Publications

2011: Sara L Montgomery; Wade C Narrow; Terry W Wright; Diala Habib; Sara A Knowlden; Michael A Mastrangelo; William J Bowers
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
The American journal of pathology 2011;179(4):2053-70.
2010: Suresh de Silva; Michael A Mastrangelo; Louis T Lotta; Clark A Burris; Zsuzsanna Izsvák; Zoltán Ivics; William J Bowers
Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo.
Human gene therapy 2010;21(11):1603-13.
2010: Maya K Desai; Michael A Mastrangelo; Deborah A Ryan; Kelly L Sudol; Wade C Narrow; William J Bowers
Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target.
The American journal of pathology 2010;177(3):1422-35.
2010: S de Silva; Michael A Mastrangelo; L T Lotta; C A Burris; Howard Federoff; William J Bowers
Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform.
Gene therapy 2010;17(3):424-31.
2009: Kelly L Sudol; Michael A Mastrangelo; Wade C Narrow; Maria E Frazer; Yona R Levites; todd golde; Howard Federoff; William J Bowers
Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(12):2031-40.
2009: Michael A Mastrangelo; Kelly L Sudol; Wade C Narrow; William J Bowers
Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice.
The American journal of pathology 2009;175(5):2076-88.
2008: Michelle C Janelsins; Michael A Mastrangelo; Keigan M Park; Kelly L Sudol; Wade C Narrow; Salvatore Oddo; Frank M LaFerla; Linda M Callahan; Howard Federoff; William J Bowers
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice.
The American journal of pathology 2008;173(6):1768-82.
2008: Maria E Frazer; Jennifer E Hughes; Michael A Mastrangelo; Jennifer L Tibbens; Howard Federoff; William J Bowers
Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):845-53.
2008: Michael A Mastrangelo; William J Bowers
Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice.
BMC neuroscience 2008;9():81.
2007: Elise B Peterson; Michael A Mastrangelo; Howard Federoff; William J Bowers
Neuronal specificity of HSV/sleeping beauty amplicon transduction in utero is driven primarily by tropism and cell type composition.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(10):1848-55.
2006: William J Bowers; Michael A Mastrangelo; Darlene F Howard; Hilary A Southerland; Kathleen A Maguire-Zeiss; Howard Federoff
Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(3):580-8.
2005: Michelle C Janelsins; Michael A Mastrangelo; Salvatore Oddo; Frank M LaFerla; Howard Federoff; William J Bowers
Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice.
Journal of neuroinflammation 2005;2():23.
2005: William J Bowers; Michael A Mastrangelo; Hilary A Stanley; Ann E Casey; Lawrence Milo; Howard Federoff
HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses.
Neurobiology of aging 2005;26(4):393-407.
2003: John A Olschowka; William J Bowers; Sean D Hurley; Michael A Mastrangelo; Howard Federoff
Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):218-27.