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Shin-Ichiro Masunaga

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Squamous Cell Carcinoma

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Gamma Rays

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Radiation Dose-Response Relationship

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Tumor Cells, Cultured

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Shin-Ichiro Masunaga; Masaru Narabayashi; Natsuko Kondo; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Hiroki Tanaka; Koji Ono
Wortmannin efficiently suppresses the recovery from radiation-induced damage in pimonidazole-unlabeled quiescent tumor cell population.
Shin-Ichiro Masunaga; Y Matsumoto; M Narabayashi; Yoshinori Sakurai; Minoru Suzuki; Hajime Tanaka; A Uzawa; Ryoichi Hirayama; N Kondo; Akira Maruhashi; Koji Ono
Radiosensitivity of pimonidazole-unlabelled intratumour quiescent cell population to γ-rays, accelerated carbon ion beams and boron neutron capture reaction.
Shin-Ichiro Masunaga; Natsuko Kondo; Yong Liu; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Hiroki Tanaka; Koji Ono
Usefulness of combined treatment with continuous administration of tirapazamine and mild temperature hyperthermia in γ-ray irradiation in terms of local tumour response and lung metastatic potential.

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2013: Shin-Ichiro Masunaga; Masaru Narabayashi; Natsuko Kondo; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Hiroki Tanaka; Koji Ono
Wortmannin efficiently suppresses the recovery from radiation-induced damage in pimonidazole-unlabeled quiescent tumor cell population.
Journal of radiation research 2013;54(2):221-9.
2013: Shin-Ichiro Masunaga; Y Matsumoto; M Narabayashi; Yoshinori Sakurai; Minoru Suzuki; Hajime Tanaka; A Uzawa; Ryoichi Hirayama; N Kondo; Akira Maruhashi; Koji Ono
Radiosensitivity of pimonidazole-unlabelled intratumour quiescent cell population to γ-rays, accelerated carbon ion beams and boron neutron capture reaction.
The British journal of radiology 2013;86(1021):20120302.
2012: Shin-Ichiro Masunaga; Natsuko Kondo; Yong Liu; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Hiroki Tanaka; Koji Ono
Usefulness of combined treatment with continuous administration of tirapazamine and mild temperature hyperthermia in γ-ray irradiation in terms of local tumour response and lung metastatic potential.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2012;28(7):636-44.
2011: Shin-Ichiro Masunaga; N Kondo; Y Liu; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Hajime Tanaka; Koji Ono
Reducing intratumour acute hypoxia through bevacizumab treatment, referring to the response of quiescent tumour cells and metastatic potential.
The British journal of radiology 2011;84(1008):1131-8.
2011: Hajime Tanaka; K Fujita; Genro Kashino; Yuko Kinashi; Y Liu; Shin-Ichiro Masunaga; T Mitsumoto; Koji Ono; Yoshinori Sakurai; Minoru Suzuki; M Takada; Akira Maruhashi
Experimental verification of beam characteristics for cyclotron-based epithermal neutron source (C-BENS).
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2011;69(12):1642-5.
2010: Shin-Ichiro Masunaga; Hideko Nagasawa; Yong Liu; Yoshinori Sakurai; Hiroki Tanaka; Genro Kashino; Minoru Suzuki; Yuko Kinashi; Koji Ono
Evaluation of the radiosensitivity of the oxygenated tumor cell fractions in quiescent cell populations within solid tumors.
Radiation research 2010;174(4):459-66.
2010: Shin-Ichiro Masunaga; Y Matsumoto; Genro Kashino; Ryoichi Hirayama; Y Liu; Hajime Tanaka; Yoshinori Sakurai; Minoru Suzuki; Yuko Kinashi; Akira Maruhashi; Koji Ono
Significance of manipulating tumour hypoxia and radiation dose rate in terms of local tumour response and lung metastatic potential, referring to the response of quiescent cell populations.
The British journal of radiology 2010;83(993):776-84.
2010: Shin-Ichiro Masunaga; Ryoichi Hirayama; Akiko Uzawa; Genro Kashino; Takushi Takata; Hiroki Tanaka; Minoru Suzuki; Yuko Kinashi; Yong Liu; Sachiko Koike; Koichi Ando; Koji Ono
Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population.
Japanese journal of radiology 2010;28(2):132-42.
2010: Genro Kashino; Yong Liu; Minoru Suzuki; Shin-Ichiro Masunaga; Yuko Kinashi; Koji Ono; Keizo Tano; Masami Watanabe
An alternative mechanism for radioprotection by dimethyl sulfoxide; possible facilitation of DNA double-strand break repair.
Journal of radiation research 2010;51(6):733-40.
2010: Shin-Ichiro Masunaga; Keizo Tano; Jun Nakamura; Masami Watanabe; Genro Kashino; Akihisa Takahashi; Hiroki Tanaka; Minoru Suzuki; Ken Ohnishi; Yuko Kinashi; Yong Liu; Takeo Ohnishi; Koji Ono
Usefulness of hexamethylenetetramine as an adjuvant to radiation and cisplatin in the treatment of solid tumors: its independency of p53 status.
Journal of radiation research 2010;51(1):27-35.
2009: Yong Liu; Kenji Nagata; Shin-Ichiro Masunaga; Minoru Suzuki; Genro Kashino; Yuko Kinashi; Hiroki Tanaka; Yoshinori Sakurai; Akira Maruhashi; Koji Ono
Gamma-ray irradiation enhanced boron-10 compound accumulation in murine tumors.
Journal of radiation research 2009;50(6):553-7.
2009: Shin-Ichiro Masunaga; Ryoichi Hirayama; Akiko Uzawa; Genro Kashino; Minoru Suzuki; Yuko Kinashi; Yong Liu; Sachiko Koike; Koichi Ando; Koji Ono
The effect of post-irradiation tumor oxygenation status on recovery from radiation-induced damage in vivo: with reference to that in quiescent cell populations.
Journal of cancer research and clinical oncology 2009;135(8):1109-16.
2009: Genro Kashino; Satoshi Fukutani; Minoru Suzuki; Yong Liu; Kenji Nagata; Shin-Ichiro Masunaga; Akira Maruhashi; Hiroki Tanaka; Yoshinori Sakurai; Yuko Kinashi; Noriko Fujii; Koji Ono
A simple and rapid method for measurement of (10)B-para-boronophenylalanine in the blood for boron neutron capture therapy using fluorescence spectrophotometry.
Journal of radiation research 2009;50(4):377-82.
2009: Shinji Kawabata; Shin-Ichi Miyatake; Naosuke Nonoguchi; Ry Hiramatsu; Kyoko Iida; Shiro Miyata; Kunio Yokoyama; Atsushi Doi; Yuzo Kuroda; Toshihiko Kuroiwa; Hiroyuki Michiue; Hiroaki Kumada; Mitsunori Kirihata; Yoshio Imahori; Akira Maruhashi; Yoshinori Sakurai; Minoru Suzuki; Shin-Ichiro Masunaga; Koji Ono
Survival benefit from boron neutron capture therapy for the newly diagnosed glioblastoma patients.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(7-8 Suppl):S15-8.
2009: H Tanaka; Yoshinori Sakurai; Minoru Suzuki; T Takata; Shin-Ichiro Masunaga; Yuko Kinashi; Genro Kashino; Y Liu; T Mitsumoto; S Yajima; H Tsutsui; M Takada; A Maruhashi; Koji Ono
Improvement of dose distribution in phantom by using epithermal neutron source based on the Be(p,n) reaction using a 30 MeV proton cyclotron accelerator.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(7-8 Suppl):S258-61.
2009: Yuko Kinashi; Minoru Suzuki; Shin-Ichiro Masunaga; Koji Ono
Bystander effect-induced mutagenicity in HPRT locus of CHO cells following BNCT neutron irradiation: characteristics of point mutations by sequence analysis.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(7-8 Suppl):S325-7.
2009: Minoru Suzuki; Hiroki Tanaka; Yoshinori Sakurai; Genro Kashino; Liu Yong; Shin-Ichiro Masunaga; Yuko Kinashi; Toshinori Mitsumoto; Satoru Yajima; Hiroshi Tsutsui; Takemi Sato; Akira Maruhashi; Koji Ono
Impact of accelerator-based boron neutron capture therapy (AB-BNCT) on the treatment of multiple liver tumors and malignant pleural mesothelioma.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2009;92(1):89-95.
2009: Genro Kashino; Takeshi Kondoh; Nobuteru Nariyama; Keiji Umetani; Takuji Ohigashi; Kunio Shinohara; Ai Kurihara; Manabu Fukumoto; Hiroki Tanaka; Akira Maruhashi; Minoru Suzuki; Yuko Kinashi; Yong Liu; Shin-Ichiro Masunaga; Masami Watanabe; Koji Ono
Induction of DNA double-strand breaks and cellular migration through bystander effects in cells irradiated with the slit-type microplanar beam of the spring-8 synchrotron.
International journal of radiation oncology, biology, physics 2009;74(1):229-36.
2009: Shin-Ichiro Masunaga; Kenji Kono; Jun Nakamura; Keizo Tano; Hiroyuki Yoshida; Masami Watanabe; Genro Kashino; Minoru Suzuki; Yuko Kinashi; Yong Liu; Koji Ono
Usefulness of hexamethylenetetramine in combination with chemotherapy using free and pegylated liposomal doxorubicin in vivo, referring to the effect on quiescent cells.
Oncology reports 2009;21(5):1307-12.
2009: Shin-Ichiro Masunaga; K Tano; Masami Watanabe; Genro Kashino; Minoru Suzuki; Yuko Kinashi; Koji Ono; Jun Nakamura
Evaluation of the potential of hexamethylenetetramine, compared with tirapazamine, as a combined agent with {gamma}-irradiation and cisplatin treatment in vivo.
The British journal of radiology 2009;82(977):392-400.
2009: Shin-Ichiro Masunaga; Yoshitaka Matsumoto; Ryoichi Hirayama; Genro Kashino; Hiroki Tanaka; Minoru Suzuki; Yuko Kinashi; Yong Liu; Koichi Ando; Koji Ono
Significance of manipulating intratumor hypoxia in the effect on lung metastases in radiotherapy, with reference to its effect on the sensitivity of intratumor quiescent cells.
Clinical & experimental metastasis 2009;26(7):693-700.
2008: Minoru Suzuki; Kazuo Endo; Hiroaki Satoh; Yoshinori Sakurai; Hiroaki Kumada; Hiroyuki Kimura; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Akira Maruhashi; Koji Ono
A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT).
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2008;88(2):192-5.
2008: Shin-Ichiro Masunaga; Koichi Ando; Akiko Uzawa; Ryoichi Hirayama; Yoshiya Furusawa; Sachiko Koike; Koji Ono
Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo.
Radiation medicine 2008;26(5):270-7.
2008: Atsushi Doi; Shinji Kawabata; Kyoko Iida; Kunio Yokoyama; Yoshinaga Kajimoto; Toshihiko Kuroiwa; Takashi Shirakawa; Mitsunori Kirihata; Satoshi Kasaoka; Kazuo Maruyama; Hiroaki Kumada; Yoshinori Sakurai; Shin-Ichiro Masunaga; Koji Ono; Shin-Ichi Miyatake
Tumor-specific targeting of sodium borocaptate (BSH) to malignant glioma by transferrin-PEG liposomes: a modality for boron neutron capture therapy.
Journal of neuro-oncology 2008;87(3):287-94.
2008: Shin-Ichiro Masunaga; Koichi Ando; Akiko Uzawa; Ryoichi Hirayama; Yoshiya Furusawa; Sachiko Koike; Koji Ono
The radiosensitivity of total and quiescent cell populations in solid tumors to 290 MeV/u carbon ion beam irradiation in vivo.
Acta oncologica (Stockholm, Sweden) 2008;47(6):1087-93.
2008: Shin-Ichiro Masunaga; Koichi Ando; Akiko Uzawa; Ryoichi Hirayama; Yoshiya Furusawa; Sachiko Koike; Yoshinori Sakurai; Kenji Nagata; Minoru Suzuki; Genro Kashino; Yuko Kinashi; Hiroki Tanaka; Akira Maruhashi; Koji Ono
Radiobiologic significance of response of intratumor quiescent cells in vivo to accelerated carbon ion beams compared with gamma-rays and reactor neutron beams.
International journal of radiation oncology, biology, physics 2008;70(1):221-8.
2007: Shin-Ichiro Masunaga; Akihisa Takahashi; Ken Ohnishi; Kenji Nagata; Minoru Suzuki; Genro Kashino; Yuko Kinashi; Takeo Ohnishi; Koji Ono
Dependency of repair of radiation-induced damage on p53 status and efficient inhibition of the repair with wortmannin treatment in vivo, with reference to the effect on intratumor quiescent cell population.
Oncology reports 2007;18(6):1589-96.
2007: Shin-Ichiro Masunaga; Kenji Nagata; Minoru Suzuki; Genro Kashino; Yuko Kinashi; Koji Ono
Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations.
Radiation medicine 2007;25(8):417-25.
2007: Genro Kashino; Kevin Prise; Keiji Suzuki; Naoki Matsuda; Seiji Kodama; Minoru Suzuki; Kenji Nagata; Yuko Kinashi; Shin-Ichiro Masunaga; Koji Ono; Masami Watanabe
Effective suppression of bystander effects by DMSO treatment of irradiated CHO cells.
Journal of radiation research 2007;48(4):327-33.
2007: Yuko Kinashi; Shin-Ichiro Masunaga; Kenji Nagata; Minoru Suzuki; Sentaro Takahashi; Koji Ono
A bystander effect observed in boron neutron capture therapy: a study of the induction of mutations in the HPRT locus.
International journal of radiation oncology, biology, physics 2007;68(2):508-14.
2007: Minoru Suzuki; Yoshinori Sakurai; Satoru Hagiwara; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Akira Maruhashi; Masatoshi Kudo; Koji Ono
First attempt of boron neutron capture therapy (BNCT) for hepatocellular carcinoma.
Japanese journal of clinical oncology 2007;37(5):376-81.
2007: Yuko Kinashi; Yoshinori Sakurai; Shin-Ichiro Masunaga; Minoru Suzuki; Kenji Nagata; Koji Ono
Evaluation of micronucleus induction in lymphocytes of patients following boron-neutron-capture-therapy: a comparison with thyroid cancer patients treated with radioiodine.
Journal of radiation research 2007;48(3):197-204.
2007: Minoru Suzuki; Yoshinori Sakurai; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Akira Maruhashi; Koji Ono
A preliminary experimental study of boron neutron capture therapy for malignant tumors spreading in thoracic cavity.
Japanese journal of clinical oncology 2007;37(4):245-9.
2007: Shin-Ichiro Masunaga; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Genro Kashino; Yuko Kinashi; Koji Ono
The usefulness of mild temperature hyperthermia combined with continuous tirapazamine administration under reduced dose-rate irradiation with gamma-rays.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2007;23(1):29-35.
2007: Shin-Ichiro Masunaga; Hideko Nagasawa; Kenji Nagata; Minoru Suzuki; Yoshihiro Uto; Hitoshi Hori; Yuko Kinashi; Koji Ono
Dependency of the effect of a vascular disrupting agent on sensitivity to tirapazamine and gamma-ray irradiation upon the timing of its administration and tumor size, with reference to the effect on intratumor quiescent cells.
Journal of cancer research and clinical oncology 2007;133(1):47-55.
2006: Shin-Ichiro Masunaga; Satoshi Kasaoka; Kazuo Maruyama; David Nigg; Yoshinori Sakurai; Kenji Nagata; Minoru Suzuki; Yuko Kinashi; Akira Maruhashi; Koji Ono
The potential of transferrin-pendant-type polyethyleneglycol liposomes encapsulating decahydrodecaborate-(10)B (GB-10) as (10)B-carriers for boron neutron capture therapy.
International journal of radiation oncology, biology, physics 2006;66(5):1515-22.
2006: Minoru Suzuki; Yoshinori Sakurai; Kenji Nagata; Yuko Kinashi; Shin-Ichiro Masunaga; Koji Ono; Akira Maruhashi; Ituro Kato; Nobukazu Fuwa; Junichi Hiratsuka; Yoshio Imahori
Impact of intra-arterial administration of boron compounds on dose-volume histograms in boron neutron capture therapy for recurrent head-and-neck tumors.
International journal of radiation oncology, biology, physics 2006;66(5):1523-7.
2006: Minoru Suzuki; Yoshinori Sakurai; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Akira Maruhashi; Koji Ono
Feasibility of boron neutron capture therapy (BNCT) for malignant pleural mesothelioma from a viewpoint of dose distribution analysis.
International journal of radiation oncology, biology, physics 2006;66(5):1584-9.
2006: Shin-Ichiro Masunaga; Yoshinori Sakurai; Kenji Nagata; Minoru Suzuki; Akira Maruhashi; Yuko Kinashi; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori; Koji Ono
The usefulness of a continuous administration of tirapazamine combined with reduced dose-rate irradiation using {gamma}-rays or reactor thermal neutrons.
The British journal of radiology 2006;79(948):991-8.
2006: Shin-Ichiro Masunaga; Hideko Nagasawa; Yoshinori Sakurai; Yoshihiro Uto; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Akira Maruhashi; Yuko Kinashi; Koji Ono
The usefulness of mild temperature hyperthermia combined with a newly developed hypoxia-oriented 10B conjugate compound, TX-2100, for boron neutron capture therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(4):287-99.
2006: Shin-Ichiro Masunaga; Yoshihiro Uto; Hideko Nagasawa; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Yuko Kinashi; Koji Ono
Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells.
Anticancer research 2006;26(2A):1261-70.
2006: Shin-Ichiro Masunaga; Hideko Nagasawa; Keiko Gotoh; Yoshinori Sakurai; Yoshihiro Uto; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Akira Maruhashi; Yuko Kinashi; Koji Ono
Evaluation of hypoxia-specific cytotoxic bioreductive agent-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
Radiation medicine 2006;24(2):98-107.
2005: Shin-Ichi Miyatake; Shinji Kawabata; Yoshinaga Kajimoto; Atsushi Aoki; Kunio Yokoyama; Makoto Yamada; Toshihiko Kuroiwa; Motomu Tsuji; Yoshio Imahori; Mitsunori Kirihata; Yoshinori Sakurai; Shin-Ichiro Masunaga; Kenji Nagata; Akira Maruhashi; Koji Ono
Modified boron neutron capture therapy for malignant gliomas performed using epithermal neutron and two boron compounds with different accumulation mechanisms: an efficacy study based on findings on neuroimages.
Journal of neurosurgery 2005;103(6):1000-9.
2005: Shin-Ichiro Masunaga; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori; Ken Ohnishi; Akihisa Takahashi; Takeo Ohnishi; Minoru Suzuki; Kenji Nagata; Yuko Kinashi; Koji Ono
Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of tumor cells.
Oncology reports 2005;14(2):393-400.
2005: Shin-Ichiro Masunaga; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori; Minoru Suzuki; Kenji Nagata; Yuko Kinashi; Koji Ono
The usefulness of continuous administration of hypoxic cytotoxin combined with mild temperature hyperthermia, with reference to effects on quiescent tumour cell populations.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(4):305-18.
2004: Shin-Ichiro Masunaga; Yoshinori Sakurai; Minoru Suzuki; Kenji Nagata; Akira Maruhashi; Yuko Kinash; Koji Ono
Combination of the vascular targeting agent ZD6126 with boron neutron capture therapy.
International journal of radiation oncology, biology, physics 2004;60(3):920-7.
2004: Shin-Ichiro Masunaga; Hideko Nagasawa; M Hiraoka; Yoshinori Sakurai; Yoshihiro Uto; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Akira Maruhashi; Yuko Kinashi; Koji Ono
The usefulness of 2-nitroimidazole-sodium borocaptate-10B conjugates as 10B-carriers in boron neutron capture therapy.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):953-8.
2004: Minoru Suzuki; Kenji Nagata; Shin-Ichiro Masunaga; Yuko Kinashi; Yoshinori Sakurai; Akira Maruhashi; Koji Ono
Biodistribution of 10B in a rat liver tumor model following intra-arterial administration of sodium borocaptate (BSH)/degradable starch microspheres (DSM) emulsion.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):933-7.
2004: Yuko Kinashi; Yoshinori Sakurai; Shin-Ichiro Masunaga; Minoru Suzuki; Kenji Nagata; Koji Ono
Ascorbic acid reduced mutagenicity at the HPRT locus in CHO cells against thermal neutron radiation.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2004;61(5):929-32.
2004: Shin-Ichiro Masunaga; Akihisa Takahashi; Ken Ohnishi; Takeo Ohnishi; Kenji Nagata; Minoru Suzuki; Yuko Kinashi; Koji Ono
Effects of mild temperature hyperthermia and p53 status on the size of hypoxic fractions in solid tumors, with reference to the effect in intratumor quiescent cell populations.
International journal of radiation oncology, biology, physics 2004;60(2):570-7.
2004: Shin-Ichiro Masunaga; Hideko Nagasawa; Masamitsu Hiraoka; Yoshinori Sakurai; Yoshihiro Uto; Hitoshi Hori; Kenji Nagata; Minoru Suzuki; Akira Maruhashi; Yuko Kinashi; Koji Ono
Applicability of the 2-nitroimidazole-sodium borocaptate-10B conjugate, TX-2060, as a 10B-carrier in boron neutron capture therapy.
Anticancer research 2004;24(5A):2975-83.
2004: Gong Li; Michihide Mitsumori; Masakazu Ogura; Naotoshi Horii; Sachiko Kawamura; Shin-Ichiro Masunaga; Yasushi Nagata; Masahiro Hiraoka
Local hyperthermia combined with external irradiation for regional recurrent breast carcinoma.
International journal of clinical oncology 2004;9(3):179-83.
2004: Minoru Suzuki; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Yoshinori Sakurai; Kiyoshi Nakamatsu; Yasumasa Nishimura; Akira Maruhashi; Koji Ono
Intra-arterial administration of sodium borocaptate (BSH)/lipiodol emulsion delivers B-10 to liver tumors highly selectively for boron neutron capture therapy: experimental studies in the rat liver model.
International journal of radiation oncology, biology, physics 2004;59(1):260-6.
2004: Minoru Suzuki; Yoshinori Sakurai; Shin-Ichiro Masunaga; Yuko Kinashi; Kenji Nagata; Koji Ono
Dosimetric study of boron neutron capture therapy with borocaptate sodium (BSH)/lipiodol emulsion (BSH/lipiodol-BNCT) for treatment of multiple liver tumors.
International journal of radiation oncology, biology, physics 2004;58(3):892-6.
2003: Yuko Kinashi; Shin-Ichiro Masunaga; Minoru Suzuki; Kenji Nagata; Koji Ono
[The biological effect of the phosphatidylinositol 3-kinase wortmannin following thermal neutron irradiation].
Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica 2003;63(8):405-8.
2003: Shin-Ichiro Masunaga; Akihisa Takahashi; Ken Ohnishi; Takeo Ohnishi; Minoru Suzuki; Kenji Nagata; Yuko Kinashi; Koji Ono
Effects of p53 status and wortmannin treatment on potentially lethal damage repair, with emphasis on the response of intratumor quiescent cells.
Radiation medicine 2003;21(3):120-7.
2003: Shin-Ichiro Masunaga; Koji Ono; Akihisa Takahashi; Ken Ohnishi; Takeo Ohnishi; Minoru Suzuki; Kenji Nagata; Yuko Kinashi; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori
Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status.
Cancer science 2003;94(1):125-33.
2003: Shin-Ichiro Masunaga; Koji Ono; Mitsunori Kirihata; Masao Takagaki; Yoshinori Sakurai; Yuko Kinashi; Tooru Kobayashi; Minoru Suzuki; Kenji Nagata; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori
Potential of alpha-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers.
Journal of cancer research and clinical oncology 2003;129(1):21-8.
2002: Shin-Ichiro Masunaga; Koji Ono; Akihisa Takahashi; Yoshinori Sakurai; Ken Ohnishi; Toru Kobayashi; Yuko Kinashi; Masao Takagaki; Takeo Ohnishi
Impact of the p53 status of the tumor cells on the effect of reactor neutron beam irradiation, with emphasis on the response of intratumor quiescent cells.
Japanese journal of cancer research : Gann 2002;93(12):1366-77.
2002: Yuko Kinashi; Shin-Ichiro Masunaga; Koji Ono
Mutagenic effect of borocaptate sodium and boronophenylalanine in neutron capture therapy.
International journal of radiation oncology, biology, physics 2002;54(2):562-7.
2002: Shin-Ichiro Masunaga; Koji Ono
Significance of the response of quiescent cell populations within solid tumors in cancer therapy.
Journal of radiation research 2002;43(1):11-25.
2002: Shin-Ichiro Masunaga; Koji Ono; Akihisa Takahashi; Takeo Ohnishi; Yuko Kinashi; Masao Takagaki
Radiobiological characteristics of solid tumours depending on the p53 status of the tumour cells, with emphasis on the response of intratumour quiescent cells.
European journal of cancer (Oxford, England : 1990) 2002;38(5):718-27.
2001: Shin-Ichiro Masunaga; Koji Ono; Yoshinori Sakurai; Masao Takagaki; Toru Kobayashi; Yuko Kinashi; Minoru Suzuki
Evaluation of apoptosis and micronucleation induced by reactor neutron beams with two different cadmium ratios in total and quiescent cell populations within solid tumors.
International journal of radiation oncology, biology, physics 2001;51(3):828-39.
2001: Shin-Ichiro Masunaga; Koji Ono; Mitsunori Kirihata; Masao Takagaki; Yoshinori Sakurai; Yuko Kinashi; Toru Kobayashi; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori
Evaluation of the potential of p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, referring to the effect on intratumor quiescent cells.
Japanese journal of cancer research : Gann 2001;92(9):996-1007.
2001: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yasumasa Nishimura; Yuko Kinashi; Masao Takagaki; Hitoshi Hori; Hideko Nagasawa; Yoshihiro Uto; I Tsuchiya; S Sadahiro; Chieko Murayama
Radiosensitization effect by combination with paclitaxel in vivo, including the effect on intratumor quiescent cells.
International journal of radiation oncology, biology, physics 2001;50(4):1063-72.
2001: Tsuneo Saga; Harumi Sakahara; Yuji Nakamoto; Noriko Sato; Takayoshi Ishimori; Marcelo Mamede; Hisataka Kobayashi; Shin-Ichiro Masunaga; K Sasai; M Kuroki; Junji Konishi
Enhancement of the therapeutic outcome of radio-immunotherapy by combination with whole-body mild hyperthermia.
European journal of cancer (Oxford, England : 1990) 2001;37(11):1429-34.
2001: Masao Takagaki; W Powell; A Sood; B F Spielvogel; Narayan S Hosmane; Mitsunori Kirihata; Koji Ono; Shin-Ichiro Masunaga; Yuko Kinashi; Shin-Ichi Miyatake; N Hashimoto
Boronated dipeptide borotrimethylglycylphenylalanine as a potential boron carrier in boron neutron capture therapy for malignant brain tumors.
Radiation research 2001;156(1):118-22.
2001: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yuko Kinashi; Masao Takagaki
Radiobiologic significance of apoptosis and micronucleation in quiescent cells within solid tumors following gamma-ray irradiation.
International journal of radiation oncology, biology, physics 2001;49(5):1361-8.
2001: Yuko Kinashi; Yoshinori Sakurai; Shin-Ichiro Masunaga; Masao Takagaki; Koji Ono
Sensitizing effect of the phosphatidylinositol 3-kinase inhibitor wortmannin on thermal neutron irradiation with or without boron compound.
Radiation medicine 2001;19(1):27-32.
2000: Minoru Suzuki; Shin-Ichiro Masunaga; Yuko Kinashi; Masao Takagaki; Yoshinori Sakurai; Toru Kobayashi; Koji Ono
The effects of boron neutron capture therapy on liver tumors and normal hepatocytes in mice.
Japanese journal of cancer research : Gann 2000;91(10):1058-64.
2000: Yuko Kinashi; Yoshinori Sakurai; Shin-Ichiro Masunaga; Minoru Suzuki; Masao Takagaki; M Akaboshi; Koji Ono
Molecular structural analysis of HPRT mutations induced by thermal and epithermal neutrons in Chinese hamster ovary cells.
Radiation research 2000;154(3):313-8.
2000: Koji Ono; Yuko Kinashi; Minoru Suzuki; Masao Takagaki; Shin-Ichiro Masunaga
The combined effect of electroporation and borocaptate in boron neutron capture therapy for murine solid tumors.
Japanese journal of cancer research : Gann 2000;91(8):853-8.
2000: Yuko Kinashi; Yoshinori Sakurai; Shin-Ichiro Masunaga; Minoru Suzuki; M Akaboshi; Koji Ono
Dimethyl sulfoxide protects against thermal and epithermal neutron-induced cell death and mutagenesis of Chinese hamster ovary (CHO) cells.
International journal of radiation oncology, biology, physics 2000;47(5):1371-8.
2000: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yuko Kinashi; Masao Takagaki; S Kasai; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori
Changes in the sensitivity of intratumor cells during fractionated tirapazamine administration.
Japanese journal of cancer research : Gann 2000;91(7):731-6.
2000: Shin-Ichiro Masunaga; Koji Ono; Yasumasa Nishimura; S Kanamori; T Saga; Minoru Suzuki; Yuko Kinashi; Masao Takagaki; S Kasai; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori
Combined effects of tirapazamine and mild hyperthermia on anti-angiogenic agent (TNP-470) treated tumors-reference to the effect on intratumor quiescent cells.
International journal of radiation oncology, biology, physics 2000;47(3):799-807.
2000: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yuko Kinashi; Masao Takagaki; Hitoshi Hori; S Kasai; Hideko Nagasawa; Yoshihiro Uto
Usefulness of tirapazamine as a combined agent in chemoradiation and thermo-chemoradiation therapy at mild temperatures: reference to the effect on intratumor quiescent cells.
Japanese journal of cancer research : Gann 2000;91(5):566-72.
2000: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yoshinori Sakurai; Toru Kobayashi; Masao Takagaki; Yuko Kinashi; M Akaboshi
Alteration of sensitivity of intratumor quiescent and total cells to gamma-rays following thermal neutron irradiation with or without 10B-compound.
International journal of radiation oncology, biology, physics 2000;46(3):653-9.
1999: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yoshinori Sakurai; Masao Takagaki; Toru Kobayashi; Yuko Kinashi; M Akaboshi
Repair of potentially lethal damage by total and quiescent cells in solid tumors following a neutron capture reaction.
Journal of cancer research and clinical oncology 1999;125(11):609-14.
1999: Shin-Ichiro Masunaga; Koji Ono; Hitoshi Hori; Minoru Suzuki; Yuko Kinashi; Masao Takagaki; S Kasai; Hideko Nagasawa; Yoshihiro Uto
Potentially lethal damage repair by total and quiescent tumor cells following various DNA-damaging treatments.
Radiation medicine 1999;17(4):259-64.
1999: Shin-Ichiro Masunaga; Koji Ono; Minoru Suzuki; Yoshinori Sakurai; Toru Kobayashi; Masao Takagaki; Yuko Kinashi; M Akaboshi
Reoxygenation in quiescent and total intratumor cells following thermal neutron irradiation with or without (10)B-compound-compared with that after gamma-ray irradiation.
International journal of radiation oncology, biology, physics 1999;44(2):391-8.
1999: Koji Ono; Shin-Ichiro Masunaga; Minoru Suzuki; Yuko Kinashi; Masao Takagaki; M Akaboshi
The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice.
International journal of radiation oncology, biology, physics 1999;43(2):431-6.
1999: Shin-Ichiro Masunaga; Koji Ono; Hitoshi Hori; Yuko Kinashi; Minoru Suzuki; Masao Takagaki; S Kasai; Hideko Nagasawa; Yoshihiro Uto
Modification of tirapazamine-induced cytotoxicity in combination with mild hyperthermia and/or nicotinamide: reference to effect on quiescent tumour cells.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(1):7-16.
1998: Shin-Ichiro Masunaga; Koji Ono; Hitoshi Hori; M Akaboshi; K Kawai; Minoru Suzuki; Yuko Kinashi; S Kasai; Hideko Nagasawa; Yoshihiro Uto
Enhancement of cisplatin sensitivity of quiescent cells in solid tumors by combined treatment with tirapazamine and low-temperature hyperthermia.
Radiation medicine 1998;16(6):441-8.
1998: Koji Ono; Yuko Kinashi; Shin-Ichiro Masunaga; Minoru Suzuki; Masao Takagaki
Electroporation increases the effect of borocaptate (10B-BSH) in neutron capture therapy.
International journal of radiation oncology, biology, physics 1998;42(4):823-6.
1998: Yuko Kinashi; M Akaboshi; Shin-Ichiro Masunaga; Koji Ono; M Watanabe
Resistance to 195mPt-radiolabeled cis-diaminedichloroplatinum (II) of SHOK cells transfected with various oncogenes.
Radiation medicine 1998;16(4):233-7.
1998: Shin-Ichiro Masunaga; Koji Ono; Yoshinori Sakurai; Hitoshi Hori; Toru Kobayashi; Masao Takagaki; Minoru Suzuki; Yuko Kinashi; M Akaboshi
Applicability of combination with tirapazamine in boron neutron capture therapy.
Japanese journal of cancer research : Gann 1998;89(7):768-74.
1997: Yuko Kinashi; Shin-Ichiro Masunaga; Masao Takagaki; Koji Ono
Mutagenic effects at HPRT locus induced in Chinese hamster ovary cells by thermal neutrons with or without boron compound.
Mutation research 1997;377(2):211-5.
1997: M Akaboshi; K Kawai; Yuko Kinashi; Shin-Ichiro Masunaga; Koji Ono
Cell-killing efficiency and number of platinum atoms binding to DNA, RNA and protein molecules of HeLa cells treated with combinations of trans-diaminedichloroplatinum(II) and hyperthermia.
Japanese journal of cancer research : Gann 1997;88(5):506-11.
1997: Yasushi Nagata; Masahiro Hiraoka; Yasumasa Nishimura; Shin-Ichiro Masunaga; M Mitumori; Y Okuno; M Fujishiro; S Kanamori; Naotoshi Horii; K Akuta; Keisuke Sasai; M Abe; Y Fukuda
Clinical results of radiofrequency hyperthermia for malignant liver tumors.
International journal of radiation oncology, biology, physics 1997;38(2):359-65.
1997: Shin-Ichiro Masunaga; Koji Ono; M Akaboshi; Masao Takagaki; Yuko Kinashi; Minoru Suzuki; M Abe
Determination and drug modification assessed by micronucleus frequency assay of potentially lethal damage repair in quiescent cell populations within murine solid tumors.
Radiation medicine 1997;15(1):37-43.