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Giuseppe Matarese

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Giuseppe Matarese; Ciro Menale; Claudio Procaccini; Jung Dae Kim; Jae Geun Kim; Veronica De Rosa; Nadia Diano; Sabrina Diano; Marcelo O Dietrich; Tamas L Horvath
Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.
Yiyun Yu; Hejian Zou; Yaoyang Liu; Giuseppe Matarese; Fu-Dong Shi; Antonio La Cava
Cutting edge: Leptin-induced RORγt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus.
Giuseppe Matarese; Hyun-Seuk Moon; Francesco Perna; Zhaoxi Wang; Kalliope Arampatzi; Mary T Brinkoetter; Sharon Chou; Chuanyun Gao; Dario Greco; Joo Young Huh; Holly P Kilim; Claudia La Rocca; Christos S Mantzoros
Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia.

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2013: Giuseppe Matarese; Ciro Menale; Claudio Procaccini; Jung Dae Kim; Jae Geun Kim; Veronica De Rosa; Nadia Diano; Sabrina Diano; Marcelo O Dietrich; Tamas L Horvath
Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(15):6193-8.
2013: Yiyun Yu; Hejian Zou; Yaoyang Liu; Giuseppe Matarese; Fu-Dong Shi; Antonio La Cava
Cutting edge: Leptin-induced RORγt expression in CD4+ T cells promotes Th17 responses in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(7):3054-8.
2013: Giuseppe Matarese; Hyun-Seuk Moon; Francesco Perna; Zhaoxi Wang; Kalliope Arampatzi; Mary T Brinkoetter; Sharon Chou; Chuanyun Gao; Dario Greco; Joo Young Huh; Holly P Kilim; Claudia La Rocca; Christos S Mantzoros
Selective capacity of metreleptin administration to reconstitute CD4+ T-cell number in females with acquired hypoleptinemia.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(9):E818-27.
2013: Anna Maria Malfitano; Clementina Manera; Giuseppe Matarese; Claudio Procaccini; Giuseppe Saccomanni; Tiziano Tuccinardi; Alba D'Alessandro; Patrizia Gazzerro; Chiara Laezza; Marco Macchia; Maurizio Bifulco
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis.
PloS one 2013;8(5):e62511.
2012: Fortunata Carbone; Claudia La Rocca; Giuseppe Matarese
Immunological functions of leptin and adiponectin.
Biochimie 2012;94(10):2082-8.
2012: Claudio Procaccini; Kui Qian; Giovanni Stallone; Petri Auvinen; Gaetano Calì; Fortunata Carbone; Silvana Cassano; Veronica De Rosa; Luigi Formisano; Mario Galgani; Dario Greco; Antonio La Cava; Giuseppe Matarese
Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(6):2941-53.
2012: Giuseppe Matarese; Veronica De Rosa
Ob-stopping obesity, metabolic and immune-mediated disorders.
Structure (London, England : 1993) 2012;20(3):385-7.
2012: Yaoyang Liu; Giuseppe Matarese; Yiyun Yu; Antonio La Cava
Cutting edge: fasting-induced hypoleptinemia expands functional regulatory T cells in systemic lupus erythematosus.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(5):2070-3.
2012: Anna Maria Malfitano; Giuseppe Matarese; Alba D'Alessandro; Mario Galgani; Patrizia Gazzerro; Chiara Laezza; Maurizio Bifulco
The CB1 receptor antagonist rimonabant controls cell viability and ascitic tumour growth in mice.
Pharmacological research : the official journal of the Italian Pharmacological Society 2012;65(3):365-71.
2011: Nicola Balato; Giuseppe Matarese; Massimiliano Nino; Cataldo Patruno; Fabio Ayala
"Eczemas" and leptin.
Dermatitis : contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group 2011;22(6):320-3.
2011: Claudio Procaccini; Fortunata Carbone; Mario Galgani; Claudia La Rocca; Veronica De Rosa; Silvana Cassano; Giuseppe Matarese
Obesity and susceptibility to autoimmune diseases.
Expert review of clinical immunology 2011;7(3):287-94.
2011: Sharon H Chou; John P Chamberland; Xiaowen Liu; Giuseppe Matarese; Chuanyun Gao; Rianna Stefanakis; Mary T Brinkoetter; Huizhi Gong; Kalliopi Arampatzi; Christos S Mantzoros
Leptin is an effective treatment for hypothalamic amenorrhea.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(16):6585-90.
2010: Mario Galgani; Claudio Procaccini; Veronica De Rosa; Fortunata Carbone; Paolo Chieffi; Antonio La Cava; Giuseppe Matarese
Leptin modulates the survival of autoreactive CD4+ T cells through the nutrient/energy-sensing mammalian target of rapamycin signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(12):7474-9.
2010: Claudio Procaccini; Veronica De Rosa; Mario Galgani; Luisa Abanni; Gaetano Calì; Antonio Porcellini; Fortunata Carbone; Silvia Fontana; Tamas L Horvath; Antonio La Cava; Giuseppe Matarese
An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Immunity 2010;33(6):929-41.
2010: Mario Galgani; Immacolata Fabozzi; Francesco Perna; Dario Bruzzese; Barbara Bellofiore; Cecilia Calabrese; Alessandro Vatrella; Domenico Galati; Giuseppe Matarese; Alessandro Sanduzzi; Marialuisa Bocchino
Imbalance of circulating dendritic cell subsets in chronic obstructive pulmonary disease.
Clinical immunology (Orlando, Fla.) 2010;137(1):102-10.
2010: Giuseppe Matarese; Pietro Biagio Carrieri; Silvana Montella; Veronica De Rosa; Antonio La Cava
Leptin as a metabolic link to multiple sclerosis.
Nature reviews. Neurology 2010;6(8):455-61.
2010: Giuseppe Matarese; Claudio Procaccini; Veronica De Rosa; Tamas L Horvath; Antonio La Cava
Regulatory T cells in obesity: the leptin connection.
Trends in molecular medicine 2010;16(6):247-56.
2010: Fortunata Carbone; Claudio Procaccini; Veronica De Rosa; Carlo Alviggi; Giuseppe De Placido; Daniel Kramer; Salvatore Longobardi; Giuseppe Matarese
Divergent immunomodulatory effects of recombinant and urinary-derived FSH, LH, and hCG on human CD4+ T cells.
Journal of reproductive immunology 2010;85(2):172-9.
2010: Claudio Procaccini; Mario Galgani; Veronica De Rosa; Fortunata Carbone; Claudia La Rocca; Giusy Ranucci; Raffaele Iorio; Giuseppe Matarese
Leptin: the prototypic adipocytokine and its role in NAFLD.
Current pharmaceutical design 2010;16(17):1902-12.
2009: Chunlin Cai; Bevra H Hahn; Giuseppe Matarese; Antonio La Cava
Leptin in non-autoimmune inflammation.
Inflammation & allergy drug targets 2009;8(4):285-91.
2009: Elaine V Lourenço; Claudio Procaccini; Francesca Ferrera; Noriko Iikuni; Ram P Singh; Gilberto Filaci; Giuseppe Matarese; Fu-Dong Shi; Ernest Brahn; Bevra H Hahn; Antonio La Cava
Modulation of p38 MAPK activity in regulatory T cells after tolerance with anti-DNA Ig peptide in (NZB x NZW)F1 lupus mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7415-21.
2009: M Galgani; A Di Giacomo; Giuseppe Matarese; Antonio La Cava
The Yin and Yang of CD4(+) regulatory T cells in autoimmunity and cancer.
Current medicinal chemistry 2009;16(35):4626-31.
2008: Giuseppe Matarese; Claudio Procaccini; Veronica De Rosa
The intricate interface between immune and metabolic regulation: a role for leptin in the pathogenesis of multiple sclerosis?
Journal of leukocyte biology 2008;84(4):893-9.
2008: Giuseppe Matarese; Veronica De Rosa; Antonio La Cava
Regulatory CD4 T cells: sensing the environment.
Trends in immunology 2008;29(1):12-7.
2007: Giuseppe Matarese; E H Leiter; Antonio La Cava
Leptin in autoimmunity: many questions, some answers.
Tissue antigens 2007;70(2):87-95.
2007: Veronica De Rosa; Claudio Procaccini; Gaetano Calì; Giuseppe Pirozzi; Silvia Fontana; Serafino Zappacosta; Antonio La Cava; Giuseppe Matarese
A key role of leptin in the control of regulatory T cell proliferation.
Immunity 2007;26(2):241-55.
2007: I Sadaf Farooqi; Teresia Wangensteen; Stephan Collins; Wendy Kimber; Giuseppe Matarese; Julia M Keogh; Emma Lank; Bill Bottomley; Judith Lopez-Fernandez; Ivan Ferraz-Amaro; Mehul T Dattani; Oya Ercan; Anne Grethe Myhre; Lars Retterstol; Richard Stanhope; Julie A Edge; Sheila McKenzie; Nader Lessan; Maryam Ghodsi; Veronica De Rosa; Francesco Perna; Silvia Fontana; Inês Barroso; DAG UNDLIEN; Stephen O'Rahilly
Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor.
The New England journal of medicine 2007;356(3):237-47.
2007: Giuseppe Matarese; Christos Mantzoros; Antonio La Cava
Leptin and adipocytokines: bridging the gap between immunity and atherosclerosis.
Current pharmaceutical design 2007;13(36):3676-80.
2006: Giuseppe De Placido; Carlo Alviggi; Roberto Clarizia; Antonio Mollo; Erminia Alviggi; Ida Strina; E Fiore; Martin Wilding; T Pagano; Giuseppe Matarese
Intra-follicular leptin concentration as a predictive factor for in vitro oocyte fertilization in assisted reproductive techniques.
Journal of endocrinological investigation 2006;29(8):719-26.
2006: Elizabeth D E Papathanassoglou; Karim El-Haschimi; Xian Chang Li; Giuseppe Matarese; Terry Strom; Christos S Mantzoros
Leptin receptor expression and signaling in lymphocytes: kinetics during lymphocyte activation, role in lymphocyte survival, and response to high fat diet in mice.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7745-52.
2006: Jean L Chan; Giuseppe Matarese; Greeshma K Shetty; Patricia Raciti; Iosif Kelesidis; Daniela Aufiero; Veronica De Rosa; Francesco Perna; Silvia Fontana; Christos S Mantzoros
Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(22):8481-6.
2006: Antonella di Palma; Giuseppe Matarese; Vincenza Leone; Tiziana di Matola; Fabio Acquaviva; Angela Maria Acquaviva; Paolo Ricchi
Aspirin reduces the outcome of anticancer therapy in Meth A-bearing mice through activation of AKT-glycogen synthase kinase signaling.
Molecular cancer therapeutics 2006;5(5):1318-24.
2006: Carlo Alviggi; Pietro Biagio Carrieri; R Pivonello; V Scarano; M Pezzella; Giuseppe De Placido; A Colao; Giuseppe Matarese
Association of pelvic endometriosis with alopecia universalis, autoimmune thyroiditis and multiple sclerosis.
Journal of endocrinological investigation 2006;29(2):182-9.
2006: Veronica De Rosa; Claudio Procaccini; Antonio La Cava; Paolo Chieffi; Giovanni Francesco Nicoletti; Silvia Fontana; Serafino Zappacosta; Giuseppe Matarese
Leptin neutralization interferes with pathogenic T cell autoreactivity in autoimmune encephalomyelitis.
The Journal of clinical investigation 2006;116(2):447-55.
2006: Raffaele Iorio; Angela Sepe; Antonietta Giannattasio; Francesco Cirillo; Maria Immacolata Spagnuolo; Adriana Franzese; Silvia Fontana; Daniela Aufiero; Francesco Perna; Angela Vegnente; Giuseppe Matarese
Immune phenotype and serum leptin in children with obesity-related liver disease.
The Journal of clinical endocrinology and metabolism 2006;91(1):341-4.
2005: Giuseppe Matarese; Pietro Biagio Carrieri; Antonio La Cava; Francesco Perna; Veronica Sanna; Veronica De Rosa; Daniela Aufiero; Silvia Fontana; Serafino Zappacosta
Leptin increase in multiple sclerosis associates with reduced number of CD4(+)CD25+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5150-5.
2005: Giuseppe Matarese; Stergios Moschos; Christos S Mantzoros
Leptin in immunology.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3137-42.
2004: Libuse Tauchmanovà; Giuseppe Matarese; Carlo Carella; Gaetano De Rosa; Bianca Serio; Patrizia Ricci; Gaetano Lombardi; Bruno Rotoli; Annamaria Colao; Carmine Selleri
High serum leptin in patients with chronic graft-versus-host disease after hematopoietic stem cell transplantation.
Transplantation 2004;78(9):1376-83.
2004: Antonio La Cava; Giuseppe Matarese
The weight of leptin in immunity.
Nature reviews. Immunology 2004;4(5):371-9.
2004: Giuseppe Matarese; Antonio La Cava
The intricate interface between immune system and metabolism.
Trends in immunology 2004;25(4):193-200.
2004: Giuseppina Ruggiero; Elena Cosentini; Delia Zanzi; Veronica Sanna; Giuseppe Terrazzano; Giuseppe Matarese; Alessandro Sanduzzi; Francesco Perna; Serafino Zappacosta
Allelic distribution of human leucocyte antigen in historical and recently diagnosed tuberculosis patients in Southern Italy.
Immunology 2004;111(3):318-22.
2004: Antonio La Cava; Carlo Alviggi; Giuseppe Matarese
Unraveling the multiple roles of leptin in inflammation and autoimmunity.
Journal of molecular medicine (Berlin, Germany) 2004;82(1):4-11.
2003: Francesco Orio; Giuseppe Matarese; Sebastiano Di Biase; Stefano Palomba; Donato Labella; Veronica Sanna; Silvia Savastano; Fulvio Zullo; Annamaria Colao; Gaetano Lombardi
Exon 6 and 2 peroxisome proliferator-activated receptor-gamma polymorphisms in polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2003;88(12):5887-92.
2003: Antonio La Cava; Giuseppe Matarese; Fanny M Ebling; Bevra H Hahn
Leptin-based immune intervention: current status and future directions.
Current opinion in investigational drugs (London, England : 2000) 2003;4(11):1327-32.
2003: Giuseppe Matarese; Giuseppe De Placido; Yorgos Nikas; Carlo Alviggi
Pathogenesis of endometriosis: natural immunity dysfunction or autoimmune disease?
Trends in molecular medicine 2003;9(5):223-8.
2003: Veronica Sanna; Antonio Di Giacomo; Antonio La Cava; Robert I Lechler; Silvia Fontana; Serafino Zappacosta; Giuseppe Matarese
Leptin surge precedes onset of autoimmune encephalomyelitis and correlates with development of pathogenic T cell responses.
The Journal of clinical investigation 2003;111(2):241-50.
2002: Giuseppe Matarese; Guido Gattinara Castelli; Caterina Cancrini; Stefania Bernardi; Maria Luisa Romiti; C Savarese; Antonio Di Giacomo; P Rossi; luigi racioppi
Serum leptin and CD4+ T lymphocytes in HIV+ children during highly active antiretroviral therapy.
Clinical endocrinology 2002;57(5):643-6.
2002: I Sadaf Farooqi; Giuseppe Matarese; Graham M Lord; Julia M Keogh; Elizabeth Lawrence; J. CHIZO AGWU; Veronica Sanna; Susan A Jebb; Francesco Perna; Silvia Fontana; Robert I Lechler; Alex M DePaoli; Stephen O'Rahilly
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.
The Journal of clinical investigation 2002;110(8):1093-103.
2002: Graham M Lord; Giuseppe Matarese; Jane K Howard; Stephen R Bloom; Robert I Lechler
Leptin inhibits the anti-CD3-driven proliferation of peripheral blood T cells but enhances the production of proinflammatory cytokines.
Journal of leukocyte biology 2002;72(2):330-8.
2002: Giuseppe Matarese; Veronica Sanna; Robert I Lechler; Nora Sarvetnick; Silvia Fontana; Serafino Zappacosta; Antonio La Cava
Leptin accelerates autoimmune diabetes in female NOD mice.
Diabetes 2002;51(5):1356-61.
2002: Giuseppe Matarese; Antonio La Cava; Veronica Sanna; Graham M Lord; Robert I Lechler; Silvia Fontana; Serafino Zappacosta
Balancing susceptibility to infection and autoimmunity: a role for leptin?
Trends in immunology 2002;23(4):182-7.
2002: Giuseppe Matarese; Veronica Sanna; Silvia Fontana; Serafino Zappacosta
Leptin as a novel therapeutic target for immune intervention.
Current drug targets. Inflammation and allergy 2002;1(1):13-22.
2001: luigi racioppi; Caterina Cancrini; Maria Luisa Romiti; F Angelini; Silvia Di Cesare; E Bertini; Susanna Livadiotti; Manuela Gambarara; Giuseppe Matarese; F Lago Paz; M Stefanini; Paolo Rossi
Defective dendritic cell maturation in a child with nucleotide excision repair deficiency and CD4 lymphopenia.
Clinical and experimental immunology 2001;126(3):511-8.
2001: Giuseppe De Placido; Carlo Alviggi; C Carravetta; ML Pisaturo; Veronica Sanna; Martin Wilding; Graham M Lord; Giuseppe Matarese
The peritoneal fluid concentration of leptin is increased in women with peritoneal but not ovarian endometriosis.
Human reproduction (Oxford, England) 2001;16(6):1251-4.
2001: Giuseppe Matarese; Antonio Di Giacomo; Veronica Sanna; Graham M Lord; Jane K Howard; A Di Tuoro; Stephen R Bloom; Robert I Lechler; Serafino Zappacosta; Silvia Fontana
Requirement for leptin in the induction and progression of autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(10):5909-16.
2001: Graham M Lord; Giuseppe Matarese; Jane K Howard; Robert I Lechler
The bioenergetics of the immune system.
Science (New York, N.Y.) 2001;292(5518):855-6.
2001: Giuseppe Matarese; Veronica Sanna; Antonio Di Giacomo; Graham M Lord; Jane K Howard; Stephen R Bloom; Robert I Lechler; Silvia Fontana; Serafino Zappacosta
Leptin potentiates experimental autoimmune encephalomyelitis in SJL female mice and confers susceptibility to males.
European journal of immunology 2001;31(5):1324-32.
2001: F Lago Paz; Mario Galgani; Ugo D'Oro; Giuseppe Matarese; Anna Maria Masci; Serafino Zappacosta; luigi racioppi
Modulation of CD45 tyrosine phosphatase activity by antigen.
European journal of immunology 2001;31(3):777-82.
2001: D Montanaro; Veronica Sanna; Giuseppe Matarese; B B Larby; luigi racioppi; Pietro Biagio Carrieri; R Bruno; N J Davey; Serafino Zappacosta; Silvia Fontana
The fine specificity of human T cell lines towards myelin basic protein peptides in southern Italian multiple sclerosis patients.
Clinical and experimental immunology 2001;123(2):288-93.
2000: Giuseppe Matarese; Carlo Alviggi; Veronica Sanna; Jane K Howard; Graham M Lord; C Carravetta; Silvia Fontana; Robert I Lechler; Stephen R Bloom; Giuseppe De Placido
Increased leptin levels in serum and peritoneal fluid of patients with pelvic endometriosis.
The Journal of clinical endocrinology and metabolism 2000;85(7):2483-7.
1999: Jane K Howard; Graham M Lord; Giuseppe Matarese; S Vendetti; Mohammad A Ghatei; M A Ritter; Robert I Lechler; Stephen R Bloom
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice.
The Journal of clinical investigation 1999;104(8):1051-9.
1999: Anna Maria Masci; F L Paz; Adriana Borriello; S Cassano; V Della Pietra; H Stoiber; Giuseppe Matarese; Fulvio Della Ragione; Serafino Zappacosta; luigi racioppi
Effects of human immunodeficiency virus type 1 on CD4 lymphocyte subset activation.
European journal of immunology 1999;29(6):1879-89.
1998: Giuseppe De Placido; Carlo Alviggi; G Di Palma; C Carravetta; Giuseppe Matarese; G Landino; luigi racioppi
Serum concentrations of soluble human leukocyte class I antigens and of the soluble intercellular adhesion molecule-1 in endometriosis: relationship with stage and non-pigmented peritoneal lesions.
Human reproduction (Oxford, England) 1998;13(11):3206-10.
1998: Graham M Lord; Giuseppe Matarese; Jane K Howard; R J Baker; Stephen R Bloom; Robert I Lechler
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression.
Nature 1998;394(6696):897-901.
1998: I Scotese; L Gaetaniello; Giuseppe Matarese; M Lecora; luigi racioppi; Claudio Pignata
T cell activation deficiency associated with an aberrant pattern of protein tyrosine phosphorylation after CD3 perturbation in Down's syndrome.
Pediatric research 1998;44(2):252-8.
1996: luigi racioppi; Giuseppe Matarese; U D'Oro; M De Pascale; Anna Maria Masci; S Fontana; Serafino Zappacosta
The role of CD4-Lck in T-cell receptor antagonism: evidence for negative signaling.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10360-5.