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Serena Materazzi

Research Profile

Chemicals & Drugs

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Anatomy

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Physiology

Gene Expression Regulation

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Publications

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Farzad Alemi; Nigel W Bunnett; Fiore Cattaruzza; Ferda Cevikbas; Graeme S Cottrell; Pierangelo Geppetti; Raquel Guerrero-Alba; Edwin Kwon; TinaMarie Lieu; Victoria Lyo; Serena Materazzi; Romina Nassini; Daniel P Poole; Kristina Schoonjans; Martin Steinhoff; Eduardo Valdez-Morales; Stephen J Vanner; Carlos U Corvera
The TGR5 receptor mediates bile acid-induced itch and analgesia.
Rebecca Edelmayer; Pierangelo Geppetti; Larry N Le; Serena Materazzi; Romina Nassini; Frank Porreca; Delia Preti; Todd W Vanderah; Xiaomei Wei; Jin Yan; Giovanni Appendino; David W Dodick; G Dussor
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain.
Gábor Pozsgai; János Szolcsányi; Ágnes Kemény; Teréz Bagoly; Melinda Boros; Zsófia Hajna; Zsuzsanna Helyes; Serena Materazzi; Romina Nassini; Erika Pintér
The role of transient receptor potential ankyrin 1 (TRPA1) receptor activation in hydrogen-sulphide-induced CGRP-release and vasodilation.

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All Publications

2013: Farzad Alemi; Nigel W Bunnett; Fiore Cattaruzza; Ferda Cevikbas; Graeme S Cottrell; Pierangelo Geppetti; Raquel Guerrero-Alba; Edwin Kwon; TinaMarie Lieu; Victoria Lyo; Serena Materazzi; Romina Nassini; Daniel P Poole; Kristina Schoonjans; Martin Steinhoff; Eduardo Valdez-Morales; Stephen J Vanner; Carlos U Corvera
The TGR5 receptor mediates bile acid-induced itch and analgesia.
The Journal of clinical investigation 2013;123(4):1513-30.
2012: Rebecca Edelmayer; Pierangelo Geppetti; Larry N Le; Serena Materazzi; Romina Nassini; Frank Porreca; Delia Preti; Todd W Vanderah; Xiaomei Wei; Jin Yan; Giovanni Appendino; David W Dodick; G Dussor
Activation of TRPA1 on dural afferents: a potential mechanism of headache pain.
Pain 2012;153(9):1949-58.
2012: Gábor Pozsgai; János Szolcsányi; Ágnes Kemény; Teréz Bagoly; Melinda Boros; Zsófia Hajna; Zsuzsanna Helyes; Serena Materazzi; Romina Nassini; Erika Pintér
The role of transient receptor potential ankyrin 1 (TRPA1) receptor activation in hydrogen-sulphide-induced CGRP-release and vasodilation.
European journal of pharmacology 2012;689(1-3):56-64.
2012: Caterina Porto; Margherita Rosa; Maria Rosaria Tuzzi; Bianca Visciano; Emma Acampora; generoso andria; Valeria Avolio; Cristina Gagliardo; Giancarlo la Marca; Serena Materazzi; Antonio Pisani; Giancarlo Parenti
Synergy between the pharmacological chaperone 1-deoxygalactonojirimycin and the human recombinant alpha-galactosidase A in cultured fibroblasts from patients with Fabry disease.
Journal of inherited metabolic disease 2012;35(3):513-20.
2012: Serena Materazzi; Silvia Benemei; Christophe Creminon; Camilla Fusi; Pierangelo Geppetti; Bernd Nilius; Riccardo Patacchini; Pamela Pedretti; Jean Prenen; Romina Nassini
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.
Pflügers Archiv : European journal of physiology 2012;463(4):561-9.
2012: Pier Giovanni Baraldi; Stefania Baraldi; Camilla Fusi; Pierangelo Geppetti; Serena Materazzi; Romina Nassini; Pamela Pedretti; Romeo Romagnoli; Giulia Saponaro; Mojgan Aghazadeh Tabrizi; Delia Preti
7-Substituted-pyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as antagonists of the transient receptor potential ankyrin 1 (TRPA1) channel: a promising approach for treating pain and inflammation.
Bioorganic & medicinal chemistry 2012;20(5):1690-8.
2012: Romina Nassini; Bernd Nilius; Frank Porreca; Jean Prenen; Delia Preti; Laura Sadofsky; Orazio Taglialatela-Scafati; Joris Vriens; Eunice Andrè; Giovanni Appendino; Cristina Avonto; Silvia Benemei; Luciano De Petrocellis; Gaetano De Siena; Vincenzo Di Marzo; Greg Dussor; Giancarlo la Marca; Serena Materazzi; Pierangelo Geppetti
The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system.
Brain : a journal of neurology 2012;135(Pt 2):376-90.
2012: Romina Nassini; Riccardo Patacchini; Pamela Pedretti; Anna Rita Pisano; Susan Stokesberry; Naila Svitacheva; Arturo Roberto Viscomi; Charlott Brunmark; Chiara Carnini; Anders B Damholt; Fabrizio Facchinetti; Camilla Fusi; Pierangelo Geppetti; Lorcan McGarvey; Nadia Moretto; Serena Materazzi
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
PloS one 2012;7(8):e42454.
2011: Romina Nassini; Bernd Nilius; Riccardo Patacchini; Pamela Pedretti; Delia Preti; Alberto Cavazzini; Gaetano De Siena; Paola Failli; Maarten Gees; Selena Harrison; Francesca Mancini; Nicola Marchetti; Serena Materazzi; Nadia Moretto; Pierangelo Geppetti
Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation.
Pain 2011;152(7):1621-31.
2010: Romina Nassini; Serena Materazzi; Eunice Andrè; Laura Sartiani; Giancarlo Aldini; Marcello Trevisani; Chiara Carnini; Daniela Massi; Pamela Pedretti; Marina Carini; Elisabetta Cerbai; Delia Preti; Gino Villetti; Maurizio Civelli; Gabriela Trevisan; Chiara Azzari; Susan Stokesberry; Laura Sadofsky; Lorcan McGarvey; Riccardo Patacchini; Pierangelo Geppetti
Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(12):4904-16.
2010: Pier Giovanni Baraldi; Delia Preti; Serena Materazzi; Pierangelo Geppetti
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Journal of medicinal chemistry 2010;53(14):5085-107.
2010: Romina Nassini; Serena Materazzi; Gaetano De Siena; Francesco De Cesaris; Pierangelo Geppetti
Transient receptor potential channels as novel drug targets in respiratory diseases.
Current opinion in investigational drugs (London, England : 2000) 2010;11(5):535-42.
2010: Romina Nassini; Eunice Andrè; David Gazzieri; Gaetano De Siena; Alessandro Zanasi; Pierangelo Geppetti; Serena Materazzi
A bicarbonate-alkaline mineral water protects from ethanol-induced hemorrhagic gastric lesions in mice.
Biological & pharmaceutical bulletin 2010;33(8):1319-23.
2010: Silvia Benemei; Francesco De Cesaris; Paola Nicoletti; Serena Materazzi; Romina Nassini; Pierangelo Geppetti
Migraine models.
Methods in molecular biology (Clifton, N.J.) 2010;617():105-14.
2009: Silvia Moretti; Romina Nassini; Francesca Prignano; Alessandra Pacini; Serena Materazzi; Antonella Naldini; A Simoni; Gianna Baroni; Silvia Pellerito; Irene Filippi; Torello Lotti; Pierangelo Geppetti; Daniela Massi
Protease-activated receptor-2 downregulation is associated to vitiligo lesions.
Pigment cell & melanoma research 2009;22(3):335-8.
2009: Serena Materazzi; R Nassini; Raffaele Gatti; Marcello Trevisani; Pierangelo Geppetti
Cough sensors. II. Transient receptor potential membrane receptors on cough sensors.
Handbook of experimental pharmacology 2009;(187):49-61.
2008: Serena Materazzi; Romina Nassini; Eunice Andrè; Barbara Campi; Silvia Amadesi; Marcello Trevisani; Nigel W Bunnett; Riccardo Patacchini; Pierangelo Geppetti
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):12045-50.
2008: Eunice Andrè; Barbara Campi; Serena Materazzi; Marcello Trevisani; Silvia Amadesi; Daniela Massi; Christophe Creminon; Natalya Vaksman; Romina Nassini; Maurizio Civelli; Pier Giovanni Baraldi; Daniel P Poole; Nigel W Bunnett; Pierangelo Geppetti; Riccardo Patacchini
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
The Journal of clinical investigation 2008;118(7):2574-82.
2008: Pierangelo Geppetti; Romina Nassini; Serena Materazzi; Silvia Benemei
The concept of neurogenic inflammation.
BJU international 2008;101 Suppl 3():2-6.
2007: Marcello Trevisani; Barbara Campi; Raffaele Gatti; Eunice André; Serena Materazzi; Paola Nicoletti; David Gazzieri; Pierangelo Geppetti
The influence of alpha1-adrenoreceptors on neuropeptide release from primary sensory neurons of the lower urinary tract.
European urology 2007;52(3):901-8.
2007: Marcello Trevisani; Jan Siemens; Serena Materazzi; Diana M Bautista; Romina Nassini; Barbara Campi; Noritaka Imamachi; Eunice Andrè; Riccardo Patacchini; Graeme S Cottrell; Raffaele Gatti; Allan I Basbaum; Nigel W Bunnett; David Julius; Pierangelo Geppetti
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(33):13519-24.
2007: Serena Materazzi; Silvia Pellerito; Claudia Di Serio; Milena Paglierani; Antonella Naldini; Camilla Ardinghi; Fabio Carraro; Pierangelo Geppetti; Giuseppe Cirino; Marco Santucci; Francesca Tarantini; Daniela Massi
Analysis of protease-activated receptor-1 and -2 in human scar formation.
The Journal of pathology 2007;212(4):440-9.
2007: Andrew D Grant; Graeme S Cottrell; Silvia Amadesi; Marcello Trevisani; Paola Nicoletti; Serena Materazzi; Christophe Altier; Nicolas Cenac; Gerald W Zamponi; Francisco Bautista-Cruz; Carlos Barajas Lopez; Elizabeth K Joseph; Jon D Levine; Wolfgang Liedtke; Stephen Vanner; Nathalie Vergnolle; Pierangelo Geppetti; Nigel W Bunnett
Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
The Journal of physiology 2007;578(Pt 3):715-33.
2006: Pierangelo Geppetti; Serena Materazzi; Paola Nicoletti
The transient receptor potential vanilloid 1: role in airway inflammation and disease.
European journal of pharmacology 2006;533(1-3):207-14.