FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Chantal Mathieu

Research Profile

Living Beings

Disorders

Type 1 Diabetes Mellitus

Chemicals & Drugs

Procedures

Anatomy

Physiology

Signal Transduction

Co-author Network

Publications

TOP 3
Tatiana Takiishi; Tom Van Belle; Conny Gysemans; Chantal Mathieu
Effects of vitamin D on antigen-specific and non-antigen-specific immune modulation: relevance for type 1 diabetes.
Michael Maris; Chantal Mathieu; Sofie Robert; Etienne Waelkens; Miriam Cnop; Rita Derua; Wannes D'Hertog; Miriam H Hernangomez; Lut Overbergh
Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction.
Anujith Kumar; Antonio Lo Nigro; Chantal Mathieu; Molly Nelson-Holte; Angelo Porciuncula; Felipe Prosper; Catherine M Verfaillie; Bert Binas; Qing Cai; Camila Esguerra; Conny Gysemans; Harry Heimberg; Yves Heremans; Bernhard Hering; María Jiménez-González; Miguel Barajas
Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Chantal Mathieu (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Tatiana Takiishi; Tom Van Belle; Conny Gysemans; Chantal Mathieu
Effects of vitamin D on antigen-specific and non-antigen-specific immune modulation: relevance for type 1 diabetes.
Pediatric diabetes 2013;14(2):81-9.
2013: Michael Maris; Chantal Mathieu; Sofie Robert; Etienne Waelkens; Miriam Cnop; Rita Derua; Wannes D'Hertog; Miriam H Hernangomez; Lut Overbergh
Role of the saturated nonesterified fatty acid palmitate in beta cell dysfunction.
Journal of proteome research 2013;12(1):347-62.
2013: Anujith Kumar; Antonio Lo Nigro; Chantal Mathieu; Molly Nelson-Holte; Angelo Porciuncula; Felipe Prosper; Catherine M Verfaillie; Bert Binas; Qing Cai; Camila Esguerra; Conny Gysemans; Harry Heimberg; Yves Heremans; Bernhard Hering; María Jiménez-González; Miguel Barajas
Reversal of hyperglycemia by insulin-secreting rat bone marrow- and blastocyst-derived hypoblast stem cell-like cells.
PloS one 2013;8(5):e63491.
2013: Chantal Mathieu; F Storms; J Tits; T F Veneman; I M Colin
Switching from premixed insulin to basal-bolus insulin glargine plus rapid-acting insulin: the ATLANTIC study.
Acta clinica Belgica 2013;68(1):28-33.
2013: Katrien Benhalima; Roland Devlieger; Myriam Hanssens; Johan Verhaeghe; Chantal Mathieu
Analysis of Pregnancy Outcomes Using the New IADPSG Recommendation Compared with the Carpenter and Coustan Criteria in an Area with a Low Prevalence of Gestational Diabetes.
International journal of endocrinology 2013;2013():248121.
2012: Hannelie Korf; Decio L Eizirik; Conny Gysemans; Michela Miani; Sofie Robert; Benoit Stijlemans; Tatiana Takiishi; Mathias Wenes; Chantal Mathieu
1,25-Dihydroxyvitamin D3 curtails the inflammatory and T cell stimulatory capacity of macrophages through an IL-10-dependent mechanism.
Immunobiology 2012;217(12):1292-300.
2012: Daniel A Cunha; Décio L Eizirik; Makiko Fukaya; Carla M Germano; Esteban N Gurzov; Conny Gysemans; Heather P Harding; Mariana Igoillo-Esteve; Piero Marchetti; Ihsane Marhfour; Lorella Marselli; Chantal Mathieu; Najib Naamane; David Ron; Jean-Marie Vanderwinden; Miriam Cnop
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.
Diabetes 2012;61(11):2763-75.
2012: F Baeke; L Ding; Conny Gysemans; H Korf; JM Laureys; T Takiishi; T L Van Belle; Chantal Mathieu
Low doses of anti-CD3, ciclosporin A and the vitamin D analogue, TX527, synergise to delay recurrence of autoimmune diabetes in an islet-transplanted NOD mouse model of diabetes.
Diabetologia 2012;55(10):2723-32.
2012: Roman Vangoitsenhoven; Chantal Mathieu; Bart Van der Schueren
GLP1 and cancer: friend or foe?
Endocrine-related cancer 2012;19(5):F77-88.
2012: Katrien Benhalima; Chantal Mathieu
The role of blood glucose monitoring in non-insulin treated type 2 diabetes: what is the evidence?
Primary care diabetes 2012;6(3):179-85.
2012: Heidi Wolden-Kirk; Annemieke Verstuyf; Conny Gysemans; Chantal Mathieu
Extraskeletal effects of vitamin D.
Endocrinology and metabolism clinics of North America 2012;41(3):571-94.
2012: K Benhalima; R Devlieger; M Hanssens; P Van Crombrugge; J Verhaeghe; Chantal Mathieu
Gestational diabetes: overview of the new consensus screening strategy and diagnostic criteria.
Acta clinica Belgica 2012;67(4):255-61.
2012: Maarten Hulsmans; Stefan Janssens; Chantal Mathieu; Peter Sinnaeve; Bart Van der Schueren; Paul Holvoet
Decreased miR-181a expression in monocytes of obese patients is associated with the occurrence of metabolic syndrome and coronary artery disease.
The Journal of clinical endocrinology and metabolism 2012;97(7):E1213-8.
2012: Isabelle Clinckspoor; Pierre Delaere; Esther Hauben; Chantal Mathieu; Annick Van den Bruel; Vincent Vander Poorten; Lieve Vanwalleghem; Lieve Verlinden; Annemieke Verstuyf; Brigitte Decallonne
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2012;60(7):502-11.
2012: Johan Verhaeghe; Erik Van Herck; Katrien Benhalima; Chantal Mathieu
Glycated hemoglobin in pregnancies at increased risk for gestational diabetes mellitus.
European journal of obstetrics, gynecology, and reproductive biology 2012;161(2):157-62.
2012: M Maris; L Overbergh; E Verdrengh; A Waget; R Burcelin; Alessandra K Cardozo; Miriam Cnop; J P M Cunha; Decio L Eizirik; T Gotoh; Conny Gysemans; Chantal Mathieu
Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance.
Diabetologia 2012;55(4):1167-78.
2012: Esteban N Gurzov; Conny Gysemans; Mariana Igoillo-Esteve; S Kitajima; P Marchetti; I Marhfour; Chantal Mathieu; Najib Naamane; Fernanda Ortis; Erwin F Wagner; Torben F Orntoft; Latifa Bakiri; J Barthson; Decio L Eizirik
Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.
Oncogene 2012;31(13):1723-32.
2012: Abhishek D Garg; Jakub Golab; Agnieszka Kaczmarek; Dmitri V Krysko; Thierry Marysael; Chantal Mathieu; Anton J M Roebroek; Noemi Rubio; Peter Vandenabeele; Tom Verfaillie; Wim Annaert; Peter De Witte; Gabriela B Ferreira; Malgorzata Firczuk; Patrizia Agostinis
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death.
The EMBO journal 2012;31(5):1062-79.
2012: Gabriela Bomfim Ferreira; Daniel Aaen Hansen; Fleur S Kleijwegt; Kasper Lage; Tatjana Nikolic; Lut Overbergh; Bart O Roep; Etienne Waelkens; Christopher T Workman; Chantal Mathieu
Differential protein pathways in 1,25-dihydroxyvitamin d(3) and dexamethasone modulated tolerogenic human dendritic cells.
Journal of proteome research 2012;11(2):941-71.
2012: Tatiana Takiishi; Roger Bouillon; Conny Gysemans; Chantal Mathieu
Vitamin D and diabetes.
Rheumatic diseases clinics of North America 2012;38(1):179-206.
2012: Liesbeth Viaene; Pieter Evenepoel; Björn Meijers; Lut Overbergh; Dirk Vanderschueren; Chantal Mathieu
Uremia suppresses immune signal-induced CYP27B1 expression in human monocytes.
American journal of nephrology 2012;36(6):497-508.
2012: Maarten Hulsmans; Chantal Mathieu; Els Van Dooren; Paul Holvoet
Decrease of miR-146b-5p in monocytes during obesity is associated with loss of the anti-inflammatory but not insulin signaling action of adiponectin.
PloS one 2012;7(2):e32794.
2012: Maarten Hulsmans; Matthias Lannoo; Chantal Mathieu; Ann Mertens; Christos Tsatsanis; Bart Vanaudenaerde; Nora Benhabiles; Dieuwke De Keyzer; Benjamine Geeraert; Marc Hoylaerts; Paul Holvoet
Interleukin-1 receptor-associated kinase-3 is a key inhibitor of inflammation in obesity and metabolic syndrome.
PloS one 2012;7(1):e30414.
2011: Heidi Wolden-Kirk; Lut Overbergh; Klaus Brusgaard; Henrik Thybo Christesen; Chantal Mathieu
Vitamin D and diabetes: its importance for beta cell and immune function.
Molecular and cellular endocrinology 2011;347(1-2):106-20.
2011: Jenny Barthson; Daniel J Drucker; Decio L Eizirik; Carla M Germano; Conny Gysemans; Andrea Jurisicova; Adriano Maida; Piero Marchetti; Chantal Mathieu; Fabrice Moore; Gabriel Nuñez; Esteban N Gurzov
Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation.
The Journal of biological chemistry 2011;286(45):39632-43.
2011: Gabriela Bomfim Ferreira; Conny Gysemans; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Mark Waer; Chantal Mathieu
1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.
Diabetes/metabolism research and reviews 2011;27(8):933-41.
2011: Gonnie M Alkemade; Robert Hilbrands; Bart Keymeulen; Chantal Mathieu; Daniel Pipeleers; Evy Vandemeulebroucke; Herman Waldmann; Bart O Roep
Preservation of recall immunity in anti-CD3-treated recent onset type 1 diabetes patients.
Diabetes/metabolism research and reviews 2011;27(8):925-7.
2011: Ben Sprangers; Bart Van der Schueren; Pieter Gillard; Chantal Mathieu
Otelixizumab in the treatment of type 1 diabetes mellitus.
Immunotherapy 2011;3(11):1303-16.
2011: Amelie Fassbender; Mutinda C. Kyama; Chantal Mathieu; Christel Meuleman; Lut Overbergh; Karen Peeraer; Carla Tomassetti; Eefje Verdrengh; Alexandra Vodolazakaia; Etienne Waelkens; Attila Bokor; Thomas M D'Hooghe
How can macroscopically normal peritoneum contribute to the pathogenesis of endometriosis?
Fertility and sterility 2011;96(3):697-9.
2011: Michael Maris; Lut Overbergh; Etienne Waelkens; Miriam Cnop; Daniel A Cunha; Wannes D'Hertog; Tatsuro Koike; Hannelie Korf; Chantal Mathieu
Oleate-induced beta cell dysfunction and apoptosis: a proteomic approach to glucolipotoxicity by an unsaturated fatty acid.
Journal of proteome research 2011;10(8):3372-85.
2011: Tom L Van Belle; Conny Gysemans; Chantal Mathieu
Vitamin D in autoimmune, infectious and allergic diseases: a vital player?
Best practice & research. Clinical endocrinology & metabolism 2011;25(4):617-32.
2011: Ilse Vermeulen; Ilse Weets; Janet M Wenzlau; Milca Asanghanwa; Frans K Gorus; John C Hutton; Bart Keymeulen; Vito Lampasona; Chantal Mathieu; Daniel G Pipeleers; Johannes Ruige; Luc Van Gaal
Contribution of antibodies against IA-2β and zinc transporter 8 to classification of diabetes diagnosed under 40 years of age.
Diabetes care 2011;34(8):1760-5.
2011: Michela Di Michele; Chantal Thys; Etienne Waelkens; Lut Overbergh; Wannes D'Hertog; Chantal Mathieu; Rita De Vos; Kathelijne Peerlinck; Chris Van Geet; Kathleen Freson
An integrated proteomics and genomics analysis to unravel a heterogeneous platelet secretion defect.
Journal of proteomics 2011;74(6):902-13.
2011: Katrien Benhalima; Eberhard Standl; Chantal Mathieu
The importance of glycemic control: how low should we go with HbA1c? Start early, go safe, go low.
Journal of diabetes and its complications 2011;25(3):202-7.
2011: Wannes D'Hertog; Michael Maris; Lieven Thorrez; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Two-dimensional gel proteome reference map of INS-1E cells.
Proteomics 2011;11(7):1365-9.
2011: Isabelle Clinckspoor; Lieve Verlinden; Lut Overbergh; Christopher Korch; Roger Bouillon; Chantal Mathieu; Annemieke Verstuyf; Brigitte Decallonne
1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer.
The Journal of steroid biochemistry and molecular biology 2011;124(1-2):1-9.
2011: Fabrice Moore; Najib Naamane; Maikel L Colli; Thomas Bouckenooghe; Fernanda Ortis; Esteban N Gurzov; Mariana Igoillo-Esteve; Chantal Mathieu; Gianluca Bontempi; Thomas Thykjaer; Torben F Ørntoft; Decio L Eizirik
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.
The Journal of biological chemistry 2011;286(2):929-41.
2011: Wim Janssens; Chantal Mathieu; Steven Boonen; Marc Decramer
Vitamin D deficiency and chronic obstructive pulmonary disease: a vicious circle.
Vitamins and hormones 2011;86():379-99.
2011: Jeroen Declercq; Caterina Di Pietro; Nadine Ectors; Conny Gysemans; Harry Heimberg; Anujith Kumar; Katleen Lemaire; Chantal Mathieu; Daniel Pipeleers; Anica Schraenen; Frans C Schuit; Marc Van de Casteele; Wim J M Van De Ven; Leentje Van Lommel; Marie Chintinne; Catherine M Verfaillie
Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism.
Cell transplantation 2011;20(8):1285-97.
2011: Lotte Jacobs; Jan Emmerechts; Marc F Hoylaerts; Chantal Mathieu; Peter H M Hoet; Benoit Nemery; Tim Nawrot
Traffic air pollution and oxidized LDL.
PloS one 2011;6(1):e16200.
2011: Femke Baeke; Hannelie Korf; Lut Overbergh; Annemieke Verstuyf; Lieven Thorrez; Leentje Van Lommel; Mark Waer; Frans Schuit; Conny Gysemans; Chantal Mathieu
The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(1):132-42.
2010: Michael Maris; Gabriela B Ferreira; Wannes D'Hertog; Miriam Cnop; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
High glucose induces dysfunction in insulin secretory cells by different pathways: a proteomic approach.
Journal of proteome research 2010;9(12):6274-87.
2010: Geoff Hale; Peppy Rebello; Ibrahim Al Bakir; Emma Bolam; Pawel Wiczling; William J Jusko; Evy Vandemeulebroucke; Bart Keymeulen; Chantal Mathieu; Annette-G Ziegler; Lucienne Chatenoud; Herman Waldmann
Pharmacokinetics and antibody responses to the CD3 antibody otelixizumab used in the treatment of type 1 diabetes.
Journal of clinical pharmacology 2010;50(11):1238-48.
2010: Wannes D'Hertog; Michael Maris; Gabriela B Ferreira; Eefje Verdrengh; Kasper Lage; Daniel A Hansen; Alessandra K Cardozo; Christopher T Workman; Yves Moreau; Decio L Eizirik; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Novel insights into the global proteome responses of insulin-producing INS-1E cells to different degrees of endoplasmic reticulum stress.
Journal of proteome research 2010;9(10):5142-52.
2010: Lien De Somer; Sabine Fevery; dominique ma bullens; Omer Rutgeerts; Caroline Lenaerts; Chantal Mathieu; Louis Boon; Ahmad Kasran; Mark Waer; An D Billiau
Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile.
Immunology letters 2010;133(1):49-53.
2010: Femke Baeke; Conny Gysemans; Hannelie Korf; Chantal Mathieu
Vitamin D insufficiency: implications for the immune system.
Pediatric nephrology (Berlin, Germany) 2010;25(9):1597-606.
2010: Chantal Mathieu
Vitamin D and diabetes: the devil is in the D-tails.
Diabetologia 2010;53(8):1545-8.
2010: Femke Baeke; Tatiana Takiishi; Hannelie Korf; Conny Gysemans; Chantal Mathieu
Vitamin D: modulator of the immune system.
Current opinion in pharmacology 2010;10(4):482-96.
2010: Femke Baeke; Hannelie Korf; Lut Overbergh; Evelyne van Etten; Annemieke Verstuyf; Conny Gysemans; Chantal Mathieu
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.
The Journal of steroid biochemistry and molecular biology 2010;121(1-2):221-7.
2010: Annemieke Verstuyf; Geert Carmeliet; Roger Bouillon; Chantal Mathieu
Vitamin D: a pleiotropic hormone.
Kidney international 2010;78(2):140-5.
2010: Tatiana Takiishi; Conny Gysemans; Roger Bouillon; Chantal Mathieu
Vitamin D and diabetes.
Endocrinology and metabolism clinics of North America 2010;39(2):419-46, table of contents.
2010: Bart Keymeulen; M Walter; Chantal Mathieu; Leonard Kaufman; Frans K Gorus; R Hilbrands; Evy Vandemeulebroucke; U Van de Velde; L Crenier; Christophe E M De Block; S Candon; H Waldmann; Anette-G Ziegler; L Chatenoud; Daniel Pipeleers
Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.
Diabetologia 2010;53(4):614-23.
2010: Geert Goderis; Liesbeth Borgermans; Richard Grol; Carine Van Den Broeke; Benoit Boland; Geert Verbeke; An Carbonez; Chantal Mathieu; Jan Heyrman
Start improving the quality of care for people with type 2 diabetes through a general practice support program: a cluster randomized trial.
Diabetes research and clinical practice 2010;88(1):56-64.
2010: Wim Janssens; Roger Bouillon; Bart Claes; Claudia Carremans; An Lehouck; Ian Buysschaert; Johan Coolen; Chantal Mathieu; Marc Decramer; Diether Lambrechts
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene.
Thorax 2010;65(3):215-20.
2010: Bart Keymeulen; Sophie Candon; Samira Fafi-Kremer; Anette Ziegler; Marianne Leruez-Ville; Chantal Mathieu; Evy Vandemeulebroucke; Markus Walter; laurent crenier; Eric THERVET; Christophe Legendre; Denis Pierard; Geoff Hale; Herman Waldmann; Jean-François Bach; Jean-Marie Seigneurin; Daniel Pipeleers; Lucienne Chatenoud
Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients.
Blood 2010;115(6):1145-55.
2010: Gabriela Bomfim Ferreira; Chantal Mathieu; Lut Overbergh
Understanding dendritic cell biology and its role in immunological disorders through proteomic profiling.
Proteomics. Clinical applications 2010;4(2):190-203.
2010: Pieter Gillard; Bart Keymeulen; Chantal Mathieu
Beta-cell transplantation in type 1 diabetic patients: a work in progress to cure.
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2010;72(1-2):71-98.
2010: Evy Vandemeulebroucke; Bart Keymeulen; Katelijn Decochez; Ilse Weets; Christophe E M De Block; Francoise Féry; U Van de Velde; I Vermeulen; Pieter De Pauw; Chantal Mathieu; Daniel G Pipeleers; Frans K Gorus
Hyperglycaemic clamp test for diabetes risk assessment in IA-2-antibody-positive relatives of type 1 diabetic patients.
Diabetologia 2010;53(1):36-44.
2009: E Huysman; Chantal Mathieu
Diabetes and peripheral vascular disease.
Acta chirurgica Belgica 2009;109(5):587-94.
2009: Robert Hilbrands; Volkert A L Huurman; Pieter Gillard; Jurjen H L Velthuis; Marc De Waele; Chantal Mathieu; Leonard Kaufman; Miriam Pipeleers-Marichal; Zhidong Ling; Babak Movahedi; Daniel Jacobs-Tulleneers-Thevissen; Diethard Monbaliu; Dirk Ysebaert; Frans K Gorus; Bart O Roep; Daniel G Pipeleers; Bart Keymeulen
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients.
Diabetes 2009;58(10):2267-76.
2009: Guy Eelen; Lieve Verlinden; JM Laureys; Suzanne Marcelis; Pierre J De Clercq; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3.
Anticancer research 2009;29(9):3579-84.
2009: Evy Vandemeulebroucke; Frans K Gorus; Katelijn Decochez; Ilse Weets; Bart Keymeulen; Christophe E M De Block; J Tits; Daniel G Pipeleers; Chantal Mathieu
Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients.
Diabetes & metabolism 2009;35(4):319-27.
2009: Gabriela Bomfim Ferreira; Evelyne van Etten; Kasper Lage; Daniel Aaen Hansen; Yves Moreau; Christopher T Workman; Mark Waer; Annemieke Verstuyf; Etienne Waelkens; Lut Overbergh; Chantal Mathieu
Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.
Proteomics 2009;9(14):3752-64.
2009: Wim Janssens; An Lehouck; Claudia Carremans; Roger Bouillon; Chantal Mathieu; Marc Decramer
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act.
American journal of respiratory and critical care medicine 2009;179(8):630-6.
2009: Pieter Gillard; Evy Vandemeulebroucke; Bart Keymeulen; Jacques Pirenne; Bart Maes; Pieter De Pauw; Yves Vanrenterghem; Daniel Pipeleers; Chantal Mathieu
Functional beta-cell mass and insulin sensitivity is decreased in insulin-independent pancreas-kidney recipients.
Transplantation 2009;87(3):402-7.
2009: Liesbeth Borgermans; Geert Goderis; Carine Van Den Broeke; Geert Verbeke; An Carbonez; Anna Ivanova; Chantal Mathieu; Bert Aertgeerts; Jan Heyrman; Richard Grol
Interdisciplinary diabetes care teams operating on the interface between primary and specialty care are associated with improved outcomes of care: findings from the Leuven Diabetes Project.
BMC health services research 2009;9():179.
2009: Geert Goderis; Liesbeth Borgermans; Chantal Mathieu; Carine Van Den Broeke; Karen Hannes; Jan Heyrman; Richard Grol
Barriers and facilitators to evidence based care of type 2 diabetes patients: experiences of general practitioners participating to a quality improvement program.
Implementation science : IS 2009;4():41.
2009: Liesbet Henckaerts; Kaspar R Nielsen; Rudi Steffensen; Kristel van Steen; Chantal Mathieu; Annapaula Giulietti; Pieter J Wouters; Ilse Milants; Ilse Vanhorebeek; Lies Langouche; Séverine Vermeire; Paul Rutgeerts; Steffen Thiel; Alexander Wilmer; Troels Krarup Hansen; Greet Van den Berghe
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit.
Critical care medicine 2009;37(1):192-201, e1-3.
2008: Femke Baeke; Evelyne van Etten; Conny Gysemans; Lut Overbergh; Chantal Mathieu
Vitamin D signaling in immune-mediated disorders: Evolving insights and therapeutic opportunities.
Molecular aspects of medicine 2008;29(6):376-87.
2008: Evelyne van Etten; Katinka Stoffels; Conny Gysemans; Chantal Mathieu; Lut Overbergh
Regulation of vitamin D homeostasis: implications for the immune system.
Nutrition reviews 2008;66(10 Suppl 2):S125-34.
2008: Roger Bouillon; Geert Carmeliet; Lieve Verlinden; Evelyne van Etten; Annemieke Verstuyf; Hilary F Luderer; Liesbet Lieben; Chantal Mathieu; Marie Demay
Vitamin D and human health: lessons from vitamin D receptor null mice.
Endocrine reviews 2008;29(6):726-76.
2008: Gabriela Bomfim Ferreira; Lut Overbergh; Evelyne van Etten; Kasper Lage; Wannes D'Hertog; Daniel Aaen Hansen; Michael Maris; Yves Moreau; Christopher T Workman; Etienne Waelkens; Chantal Mathieu
Protein-induced changes during the maturation process of human dendritic cells: A 2-D DIGE approach.
Proteomics. Clinical applications 2008;2(9):1349-60.
2008: Isabelle Meyts; Jeroen A J Vanoirbeek; Greet Hens; Bart M Vanaudenaerde; Bert Verbinnen; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens; Peter W Hellings
T-cell mediated late increase in bronchial tone after allergen provocation in a murine asthma model.
Clinical immunology (Orlando, Fla.) 2008;128(2):248-58.
2008: Babak Movahedi; Conny Gysemans; Daniel Jacobs-Tulleneers-Thevissen; Chantal Mathieu; Daniel Pipeleers
Pancreatic duct cells in human islet cell preparations are a source of angiogenic cytokines interleukin-8 and vascular endothelial growth factor.
Diabetes 2008;57(8):2128-36.
2008: Daniel Cunha; Paul Hekerman; Laurence Ladrière; Angie Bazarra-Castro; Fernanda Ortis; Marion C Wakeham; Fabrice Moore; Joanne Rasschaert; Alessandra K Cardozo; Elisa Bellomo; Lutgart Overbergh; Chantal Mathieu; Roberto Lupi; Tsonwin Hai; Andre Herchuelz; Piero Marchetti; Guy Rutter; Decio L Eizirik; Miriam Cnop
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells.
Journal of cell science 2008;121(Pt 14):2308-18.
2008: K Benhalima; Chantal Mathieu; Eric Van Wijngaerden
Disorders of glucose metabolism in human immunodeficiency virus-infected patients.
Acta clinica Belgica 2008;63(4):227-34.
2008: Conny Gysemans; Hanne Callewaert; Lut Overbergh; Chantal Mathieu
Cytokine signalling in the beta-cell: a dual role for IFNgamma.
Biochemical Society transactions 2008;36(Pt 3):328-33.
2008: Timothy Devos; Li Shengqiao; Conny Gysemans; Yehong Yan; Boudewijn Van Damme; Molly Nelson-Holte; An D Billiau; Mark Waer; Chantal Mathieu
Late CD8+ T cell-dependent xenoantibody production in innate tolerant nude rats after hamster islet grafting but not after hamster heart grafting.
Transplantation 2008;85(10):1489-95.
2008: Zeynep Dogusan; Mónica García; Daisy Flamez; Lena Alexopoulou; Michel Goldman; Conny Gysemans; Chantal Mathieu; Claude Libert; Decio L Eizirik; Joanne Rasschaert
Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.
Diabetes 2008;57(5):1236-45.
2008: Mutinda C. Kyama; Lut Overbergh; Attila Mihalyi; Silvio Cuneo; Daniel Chivatsi Chai; Sophie Debrock; Jason M Mwenda; Chantal Mathieu; Noreen P Nugent; Thomas M D'Hooghe
Effect of recombinant human TNF-binding protein-1 and GnRH antagonist on mRNA expression of inflammatory cytokines and adhesion and growth factors in endometrium and endometriosis tissues in baboons.
Fertility and sterility 2008;89(5 Suppl):1306-13.
2008: Michael Maris; Wannes D'Hertog; Lut Overbergh; Chantal Mathieu
Proteomics as a tool to discover biomarkers for the prediction of diabetic complications.
Expert opinion on medical diagnostics 2008;2(3):277-87.
2008: Michael Maris; Lut Overbergh; Chantal Mathieu
Type 2 diabetes: Gaining insight into the disease process using proteomics.
Proteomics. Clinical applications 2008;2(3):312-26.
2008: Timothy Devos; Ben Sprangers; Yuan Lin; Shengqiao Li; Yehong Yan; Willy Landuyt; Caroline Lenaerts; Omer Rutgeerts; Jozef Goebels; dominique ma bullens; Christiane De Wolf-Peeters; Chantal Mathieu; Mark Waer; An D Billiau
Occurrence of autoimmunity after xenothymus transplantation in T-cell-deficient mice depends on the thymus transplant technique.
Transplantation 2008;85(4):640-4.
2008: Mutinda C. Kyama; Lut Overbergh; Attila Mihalyi; Christel Meuleman; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Endometrial and peritoneal expression of aromatase, cytokines, and adhesion factors in women with endometriosis.
Fertility and sterility 2008;89(2):301-10.
2008: Pieter Gillard; Zhidong Ling; Chantal Mathieu; laurent crenier; Matthias Lannoo; Bart Maes; Bart Roep; Frans K Gorus; Daniel Pipeleers; Bart Keymeulen
Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts.
Transplantation 2008;85(2):256-63.
2008: Chantal Mathieu; Evy Degrande
Vildagliptin: a new oral treatment for type 2 diabetes mellitus.
Vascular health and risk management 2008;4(6):1349-60.
2008: Chantal Mathieu; E A M Gale
Inhaled insulin: gone with the wind?
Diabetologia 2008;51(1):1-5.
2008: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annapaula Giulietti; Guy Eelen; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.
Diabetes 2008;57(1):269-75.
2007: Wannes D'Hertog; Lut Overbergh; Kasper Lage; Gabriela Bonfim Ferreira; Michael Maris; Conny Gysemans; Daisy Flamez; Alessandra Kupper Cardozo; Gert Van den Bergh; Liliane Schoofs; Lutgarde Arckens; Yves Moreau; Daniel Aaen Hansen; Decio L Eizirik; Ettienne Waelkens; Chantal Mathieu
Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.
Molecular & cellular proteomics : MCP 2007;6(12):2180-99.
2007: Hanne Callewaert; Conny Gysemans; Laurence Ladrière; Wannes D'Hertog; Julianna Hagenbrock; Lut Overbergh; Decio L Eizirik; Chantal Mathieu
Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection.
Diabetes 2007;56(8):2169-73.
2007: Annapaula Giulietti; Evelyne van Etten; Lut Overbergh; Katinka Stoffels; Roger Bouillon; Chantal Mathieu
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory.
Diabetes research and clinical practice 2007;77(1):47-57.
2007: Kurt Boonen; Geert Baggerman; Wannes D'Hertog; Steven J Husson; Lut Overbergh; Chantal Mathieu; Liliane Schoofs
Neuropeptides of the islets of Langerhans: a peptidomics study.
General and comparative endocrinology 2007;152(2-3):231-41.
2007: Katinka Stoffels; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Immune regulation of 1alpha-hydroxylase in murine peritoneal macrophages: unravelling the IFNgamma pathway.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):567-71.
2007: Evelyne van Etten; Conny Gysemans; Dumitru D Branisteanu; Annemieke Verstuyf; Roger Bouillon; Lut Overbergh; Chantal Mathieu
Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):546-51.
2007: Lieve Verlinden; Guy Eelen; Ruth Van Hellemont; Kristof Engelen; Ine Beullens; Mark Van Camp; Kathleen Marchal; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):411-5.
2007: Evelyne van Etten; Lieve Verlinden; Annapaula Giulietti; Elizabeth Ramos Lopez; Dumitru D Branisteanu; Gabriela B Ferreira; Lut Overbergh; Annemieke Verstuyf; Roger Bouillon; Bart O Roep; Klaus Badenhoop; Chantal Mathieu
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.
European journal of immunology 2007;37(2):395-405.
2007: Hanne Callewaert; Conny Gysemans; Alessandra K Cardozo; Matthias Elsner; Markus Tiedge; Decio L Eizirik; Chantal Mathieu
Cell loss during pseudoislet formation hampers profound improvements in islet lentiviral transduction efficacy for transplantation purposes.
Cell transplantation 2007;16(5):527-37.
2007: Guy Eelen; Conny Gysemans; Lieve Verlinden; E Vanoirbeek; Pierre J De Clercq; Dirk Van Haver; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Mechanism and potential of the growth-inhibitory actions of vitamin D and ana-logs.
Current medicinal chemistry 2007;14(17):1893-910.
2006: Roger Bouillon; Annemieke Verstuyf; Chantal Mathieu; Sophie van Cromphaut; Ritsuko Masuyama; Petra Dehaes; Geert Carmeliet
Vitamin D resistance.
Best practice & research. Clinical endocrinology & metabolism 2006;20(4):627-45.
2006: Roger Bouillon; Guy Eelen; Lieve Verlinden; Chantal Mathieu; Geert Carmeliet; Annemieke Verstuyf
Vitamin D and cancer.
The Journal of steroid biochemistry and molecular biology 2006;102(1-5):156-62.
2006: Isabelle Meyts; Peter W Hellings; Greet Hens; Bart M Vanaudenaerde; Bert Verbinnen; Hubertine Heremans; Patrick Matthys; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Kris De Boeck; Jan L Ceuppens
IL-12 contributes to allergen-induced airway inflammation in experimental asthma.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(9):6460-70.
2006: Peter W Hellings; Ahmad Kasran; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Hubertine Heremans; Patrick Matthys; Louis Boon; Mark Jorissen; Jan L Ceuppens
IL-10- and IL-12-independent down-regulation of allergic sensitization by stimulation of CD40 signaling.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5138-44.
2006: Lut Overbergh; Katinka Stoffels; Mark Waer; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
The Journal of clinical endocrinology and metabolism 2006;91(9):3566-74.
2006: Mutinda C. Kyama; Lut Overbergh; Sophie Debrock; Dirk Valckx; Sarah Vander Perre; Christel Meuleman; Attila Mihalyi; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Increased peritoneal and endometrial gene expression of biologically relevant cytokines and growth factors during the menstrual phase in women with endometriosis.
Fertility and sterility 2006;85(6):1667-75.
2006: Wannes D'Hertog; Chantal Mathieu; Lut Overbergh
Type 1 diabetes: entering the proteomic era.
Expert review of proteomics 2006;3(2):223-36.
2006: Björn Ellger; Yves Debaveye; Ilse Vanhorebeek; Lies Langouche; Annapaula Giulietti; Evelyne van Etten; Paul Herijgers; Chantal Mathieu; Greet Van den Berghe
Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin.
Diabetes 2006;55(4):1096-105.
2006: Philippe Maerten; B S Kwon; Chong Shen; Gert De Hertogh; Pascal Cadot; dominique ma bullens; Lut Overbergh; Chantal Mathieu; Gert van Assche; Karel Geboes; Paul Rutgeerts; Jan L Ceuppens
Involvement of 4-1BB (CD137)-4-1BBligand interaction in the modulation of CD4 T cell-mediated inflammatory colitis.
Clinical and experimental immunology 2006;143(2):228-36.
2006: Lut Overbergh; Conny Gysemans; Chantal Mathieu
Quantification of chemokines by real-time reverse transcriptase PCR: applications in type 1 diabetes.
Expert review of molecular diagnostics 2006;6(1):51-64.
2006: Katinka Stoffels; Lut Overbergh; Annapaula Giulietti; Lieve Verlinden; Roger Bouillon; Chantal Mathieu
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(1):37-47.
2005: Lieve Verlinden; Guy Eelen; Ine Beullens; Mark Van Camp; Paul van Hummelen; Kristof Engelen; Ruth Van Hellemont; Kathleen Marchal; Bart De Moor; Floris Foijer; Hein te Riele; Monique Beullens; Mathieu Bollen; Chantal Mathieu; Roger Bouillon; Annemieke Verstuyf
Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.
The Journal of biological chemistry 2005;280(45):37319-30.
2005: Hiroaki Kitade; Masaru Kawai; Omer Rutgeerts; Willy Landuyt; Mark Waer; Chantal Mathieu; Jacques Pirenne
Early presence of regulatory cells in transplanted rats rendered tolerant by donor-specific blood transfusion.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4963-70.
2005: Joanne Rasschaert; Laurence Ladrière; Maryse Urbain; Zeynep Dogusan; Bitty Katabua; Shintaro Sato; Shizuo Akira; Conny Gysemans; Chantal Mathieu; Decio L Eizirik
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells.
The Journal of biological chemistry 2005;280(40):33984-91.
2005: Roger Bouillon; Lieve Verlinden; Guy Eelen; Pierre J De Clercq; Maurits Vandewalle; Chantal Mathieu; Annemieke Verstuyf
Mechanisms for the selective action of Vitamin D analogs.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):21-30.
2005: Evelyne van Etten; Chantal Mathieu
Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts.
The Journal of steroid biochemistry and molecular biology 2005;97(1-2):93-101.
2005: Lut Overbergh; Mutinda C. Kyama; Dirk Valckx; Sophie Debrock; Jason M Mwenda; Chantal Mathieu; Thomas M D'Hooghe
Validation of real-time RT-PCR assays for mRNA quantification in baboons.
Cytokine 2005;31(6):454-8.
2005: Chantal Mathieu
Diabetes and pregnancy: beyond glucose?
Diabetologia 2005;48(9):1714-5.
2005: Conny Gysemans; Roger Bouillon; Chantal Mathieu
The sunshine hormone vitamin D and its association with type 1 diabetes.
Discovery medicine 2005;5(28):399-402.
2005: Conny Gysemans; Laurence Ladrière; Hanne Callewaert; Joanne Rasschaert; Daisy Flamez; David E Levy; Patrick Matthys; Decio L Eizirik; Chantal Mathieu
Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.
Diabetes 2005;54(8):2396-403.
2005: Chantal Mathieu; Klaus Badenhoop
Vitamin D and type 1 diabetes mellitus: state of the art.
Trends in endocrinology and metabolism: TEM 2005;16(6):261-6.
2005: Chantal Mathieu; Conny Gysemans; Annapaula Giulietti; Roger Bouillon
Vitamin D and diabetes.
Diabetologia 2005;48(7):1247-57.
2005: Brigitte Decallonne; Evelyne van Etten; Lut Overbergh; Dirk Valckx; Roger Bouillon; Chantal Mathieu
1Alpha,25-dihydroxyvitamin D3 restores thymocyte apoptosis sensitivity in non-obese diabetic (NOD) mice through dendritic cells.
Journal of autoimmunity 2005;24(4):281-9.
2005: Masaru Kawai; Hiroaki Kitade; Chantal Mathieu; Mark Waer; Jacques Pirenne
Inhibitory and stimulatory effects of cyclosporine A on the development of regulatory T cells in vivo.
Transplantation 2005;79(9):1073-7.
2005: Conny Gysemans; Alessandra K Cardozo; Hanne Callewaert; Annapaula Giulietti; Leen Hulshagen; Roger Bouillon; Decio L Eizirik; Chantal Mathieu
1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice.
Endocrinology 2005;146(4):1956-64.
2005: Jacques Pirenne; Hiroaki Kitade; Masaru Kawai; Takaaki Koshiba; Boudewijn Van Damme; Chantal Mathieu; Mark Waer
Regulatory cells, TH1/TH2 unbalance, and antibody-induced chronic rejection in operational tolerance induced by donor-specific blood transfusion.
Transplantation 2005;79(3 Suppl):S25-7.
2005: Timothy Devos; Yehong Yan; Constant Segers; Omer Rutgeerts; JM Laureys; Conny Gysemans; Chantal Mathieu; Mark Waer
Role of CD4+ and CD8+ T cells in the rejection of heart or islet xenografts in recipients with xenotolerance in the innate immune compartment.
Transplantation proceedings 2005;37(1):516-7.
2004: Hiroaki Kitade; Masaru Kawai; Takaaki Koshiba; Annapaula Giulietti; Lut Overbergh; Omer Rutgeerts; Dirk Valckx; Mark Waer; Chantal Mathieu; Jacques Pirenne
Early accumulation of interferon-gamma in grafts tolerized by donor-specific blood transfusion: friend or enemy?
Transplantation 2004;78(12):1747-55.
2004: Evelyne van Etten; Olivier Dardenne; Conny Gysemans; Lut Overbergh; Chantal Mathieu
1,25-Dihydroxyvitamin D3 alters the profile of bone marrow-derived dendritic cells of NOD mice.
Annals of the New York Academy of Sciences 2004;1037():186-92.
2004: Annapaula Giulietti; Katinka Stoffels; Brigitte Decallonne; Lut Overbergh; Chantal Mathieu
Monocytic expression behavior of cytokines in diabetic patients upon inflammatory stimulation.
Annals of the New York Academy of Sciences 2004;1037():74-8.
2004: Katinka Stoffels; Lut Overbergh; Annapaula Giulietti; Ahmad Kasran; Roger Bouillon; Conny Gysemans; Chantal Mathieu
NOD macrophages produce high levels of inflammatory cytokines upon encounter of apoptotic or necrotic cells.
Journal of autoimmunity 2004;23(1):9-15.
2004: Evelyne van Etten; Brigitte Decallonne; Roger Bouillon; Chantal Mathieu
NOD bone marrow-derived dendritic cells are modulated by analogs of 1,25-dihydroxyvitamin D3.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):457-9.
2004: Lut Overbergh; Katinka Stoffels; Dirk Valckx; Annapaula Giulietti; Roger Bouillon; Chantal Mathieu
Regulation of 25-hydroxyvitamin d-1alpha-hydroxylase by IFNgamma in human monocytic THP1 cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):453-5.
2004: Chantal Mathieu; Evelyne van Etten; Brigitte Decallonne; Annapaula Guilietti; Conny Gysemans; Roger Bouillon; Lut Overbergh
Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):449-52.
2004: Guy Eelen; Lieve Verlinden; Mark Van Camp; Chantal Mathieu; Geert Carmeliet; Roger Bouillon; Annemieke Verstuyf
Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells.
The Journal of steroid biochemistry and molecular biology 2004;89-90(1-5):405-7.
2004: Annapaula Giulietti; Conny Gysemans; Katinka Stoffels; Evelyne van Etten; Brigitte Decallonne; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Vitamin D deficiency in early life accelerates Type 1 diabetes in non-obese diabetic mice.
Diabetologia 2004;47(3):451-62.
2004: Guy Eelen; Lieve Verlinden; Mark Van Camp; Paul van Hummelen; Kathleen Marchal; Bart De Moor; Chantal Mathieu; Geert Carmeliet; Roger Bouillon; Annemieke Verstuyf
The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(1):133-46.
2003: Takaaki Koshiba; Hiroaki Kitade; Mark Waer; Chantal Mathieu; Boudewijn Van Damme; Jacques Pirenne
Break of tolerance via donor-specific blood transfusion by high doses of steroids: a differential effect after intestinal transplantation and heart transplantation.
Transplantation proceedings 2003;35(8):3153-5.
2003: Frank Weekers; Annapaula Giulietti; Marina Michalaki; Willy Coopmans; Erik Van Herck; Chantal Mathieu; Greet Van den Berghe
Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness.
Endocrinology 2003;144(12):5329-38.
2003: Dumitru D Branisteanu; Lut Overbergh; Brigitte Decallonne; Chantal Mathieu
Hen egg white lysozyme vaccination induces acute shock in NOD mice.
Annals of the New York Academy of Sciences 2003;1005():215-7.
2003: Brigitte Decallonne; Chantal Mathieu
Defective activation-induced cell death in NOD T lymphocytes: 1,25-dihydroxyvitamin D3 restores defect.
Annals of the New York Academy of Sciences 2003;1005():176-7.
2003: Takaaki Koshiba; Hiroaki Kitade; Boudewijn Van Damme; Annapaula Giulietti; Lut Overbergh; Chantal Mathieu; Mark Waer; Jacques Pirenne
Regulatory cell-mediated tolerance does not protect against chronic rejection.
Transplantation 2003;76(3):588-96.
2003: Conny Gysemans; Katinka Stoffels; Annapaula Giulietti; Lut Overbergh; Mark Waer; M Lannoo; Ulrich Feige; Chantal Mathieu
Prevention of primary non-function of islet xenografts in autoimmune diabetic NOD mice by anti-inflammatory agents.
Diabetologia 2003;46(8):1115-23.
2003: Ruth J F Loos; Johan Verhaeghe; Francis de Zegher; Gaston Beunen; Catherine Derom; Robert Fagard; Chantal Mathieu; Robert Francois Vlietinck
Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives.
Journal of human hypertension 2003;17(7):481-5.
2003: Kristina Casteels; Chantal Mathieu
Diabetic ketoacidosis.
Reviews in endocrine & metabolic disorders 2003;4(2):159-66.
2003: Brigitte Decallonne; Evelyne van Etten; Annapaula Giulietti; Kristina Casteels; Lut Overbergh; Roger Bouillon; Chantal Mathieu
Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes.
Journal of autoimmunity 2003;20(3):219-26.
2003: Evelyne van Etten; Dumitru D Branisteanu; Lut Overbergh; Roger Bouillon; Annemieke Verstuyf; Chantal Mathieu
Combination of a 1,25-dihydroxyvitamin D3 analog and a bisphosphonate prevents experimental autoimmune encephalomyelitis and preserves bone.
Bone 2003;32(4):397-404.
2003: Lut Overbergh; Annapaula Giulietti; Dirk Valckx; R Decallonne; Roger Bouillon; Chantal Mathieu
The use of real-time reverse transcriptase PCR for the quantification of cytokine gene expression.
Journal of biomolecular techniques : JBT 2003;14(1):33-43.
2003: Takaaki Koshiba; Annapaula Giulietti; Boudewijn Van Damme; Lut Overbergh; Omer Rutgeerts; Hiroaki Kitade; Mark Waer; Chantal Mathieu; Jacques Pirenne
Paradoxical early upregulation of intragraft Th1 cytokines is associated with graft acceptance following donor-specific blood transfusion.
Transplant international : official journal of the European Society for Organ Transplantation 2003;16(3):179-85.
2003: Dumitru D Brănişteanu; Chantal Mathieu
Progesterone in gestational diabetes mellitus: guilty or not guilty?
Trends in endocrinology and metabolism: TEM 2003;14(2):54-6.
2003: Alessandra K Cardozo; P Proost; Conny Gysemans; M-C Chen; Chantal Mathieu; Decio L Eizirik
IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.
Diabetologia 2003;46(2):255-66.
2003: Paul Enzlin; Chantal Mathieu; Annick Van den Bruel; Dirk Vanderschueren; Koen Demyttenaere
Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes.
Diabetes care 2003;26(2):409-14.
2003: Lut Overbergh; Brigitte Decallonne; Dumitru D Branisteanu; Dirk Valckx; Ahmad Kasran; Roger Bouillon; Chantal Mathieu
Acute shock induced by antigen vaccination in NOD mice.
Diabetes 2003;52(2):335-41.
2003: Evelyne van Etten; Brigitte Decallonne; Lieve Verlinden; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators.
Journal of cellular biochemistry 2003;88(2):223-6.
2003: Roger Bouillon; Annemieke Verstuyf; Lieve Verlinden; Guy Eelen; Chantal Mathieu
Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 2003;164():353-6.
2003: Peter W Hellings; Ahmad Kasran; Zhanju Liu; Philippe Vandekerckhove; Anja Wuyts; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma.
American journal of respiratory cell and molecular biology 2003;28(1):42-50.
2002: Kathleen Claes; Dirk Kuypers; Pieter Evenepoel; Bart Maes; Tania Roskams; Raymond Aerts; Jacques Pirenne; Chantal Mathieu; Yves Vanrenterghem
An uncommon tumor in a renal graft recipient: a diagnostic and therapeutic challenge.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2002;40(6):E21.
2002: Ruth J F Loos; David I W Phillips; Robert Fagard; Gaston Beunen; Catherine Derom; Chantal Mathieu; Johan Verhaeghe; Robert Francois Vlietinck
The influence of maternal BMI and age in twin pregnancies on insulin resistance in the offspring.
Diabetes care 2002;25(12):2191-6.
2002: Paul Enzlin; Chantal Mathieu; Koen Demyttenaere
Gender differences in the psychological adjustment to type 1 diabetes mellitus: an explorative study.
Patient education and counseling 2002;48(2):139-45.
2002: Evelyne van Etten; Brigitte Decallonne; Chantal Mathieu
1,25-dihydroxycholecalciferol: endocrinology meets the immune system.
The Proceedings of the Nutrition Society 2002;61(3):375-80.
2002: Conny Gysemans; Evelyne van Etten; Lut Overbergh; Annemieke Verstuyf; Mark Waer; Roger Bouillon; Chantal Mathieu
Treatment of autoimmune diabetes recurrence in non-obese diabetic mice by mouse interferon-beta in combination with an analogue of 1alpha,25-dihydroxyvitamin-D3.
Clinical and experimental immunology 2002;128(2):213-20.
2002: Chantal Mathieu; Evelyne van Etten; Conny Gysemans; Brigitte Decallonne; Roger Bouillon
Seasonality of birth in patients with type 1 diabetes.
Lancet 2002;359(9313):1248.
2002: Chantal Mathieu; Luciano Adorini
The coming of age of 1,25-dihydroxyvitamin D(3) analogs as immunomodulatory agents.
Trends in molecular medicine 2002;8(4):174-9.
2002: Paul Enzlin; Chantal Mathieu; Annick Van den Bruel; Jan Bosteels; Dirk Vanderschueren; Koen Demyttenaere
Sexual dysfunction in women with type 1 diabetes: a controlled study.
Diabetes care 2002;25(4):672-7.
2002: Peter W Hellings; Peter Vandenberghe; Ahmad Kasran; Lieve Coorevits; Lut Overbergh; Chantal Mathieu; Jan L Ceuppens
Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice.
European journal of immunology 2002;32(2):585-94.
2002: Chantal Mathieu; Brigitte Decallonne; Evelyne van Etten
[1,25-dihydroxyvitamin D3: the endocrine system meets the immune system].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2002;64(1):71-80; discussion 80-2.
2001: Annapaula Giulietti; Lut Overbergh; Dirk Valckx; Brigitte Decallonne; Roger Bouillon; Chantal Mathieu
An overview of real-time quantitative PCR: applications to quantify cytokine gene expression.
Methods (San Diego, Calif.) 2001;25(4):386-401.
2001: Chantal Mathieu; Evelyne van Etten; Conny Gysemans; Brigitte Decallonne; S Kato; JM Laureys; J Depovere; Dirk Valckx; Annemieke Verstuyf; Roger Bouillon
In vitro and in vivo analysis of the immune system of vitamin D receptor knockout mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(11):2057-65.
2001: Zhanju Liu; Karel Geboes; Hubertine Heremans; Lut Overbergh; Chantal Mathieu; Paul Rutgeerts; Jan L Ceuppens
Role of interleukin-12 in the induction of mucosal inflammation and abrogation of regulatory T cell function in chronic experimental colitis.
European journal of immunology 2001;31(5):1550-60.
2001: Conny Gysemans; D Pavlovic; Roger Bouillon; Decio L Eizirik; Chantal Mathieu
Dual role of interferon-gamma signalling pathway in sensitivity of pancreatic beta cells to immune destruction.
Diabetologia 2001;44(5):567-74.
2001: Conny Gysemans; Mark Waer; JM Laureys; Roger Bouillon; Chantal Mathieu
A combination of KH1060, a vitamin D(3) analogue, and cyclosporin prevents early graft failure and prolongs graft survival of xenogeneic islets in nonobese diabetic mice.
Transplantation proceedings 2001;33(3):2365.
2001: Evelyne van Etten; Conny Gysemans; Annemieke Verstuyf; Roger Bouillon; Chantal Mathieu
Immunomodulatory properties of a 1,25(OH)(2) vitamin D(3) analog combined with IFNbeta in an animal model of syngeneic islet transplantation.
Transplantation proceedings 2001;33(3):2319.
2001: Conny Gysemans; Mark Waer; JM Laureys; Roger Bouillon; Chantal Mathieu
Leflunomide and its analogue X920715 synergize with cyclosporin A in preventing early graft failure and delaying graft rejection of xenogeneic islets in nonobese diabetic mice.
Transplantation proceedings 2001;33(3):2094-5.
2001: Chantal Mathieu
Current limitations of islet transplantation.
Transplantation proceedings 2001;33(1-2):1707-8.
2001: Takaaki Koshiba; Boudewijn Van Damme; Ping Ji; Y Lu; Yehong Yan; Hassan Sefrioui; Omer Rutgeerts; Lut Overbergh; K Tanaka; Chantal Mathieu; Mark Waer; Jacques Pirenne
Intestinal allografts delay rejection and prolong survival of combined donor-specific and third party solid organ transplants.
Transplantation proceedings 2001;33(1-2):1550-2.
2001: Takaaki Koshiba; Boudewijn Van Damme; Ping Ji; Y Lu; Hassan Sefrioui; Lut Overbergh; K Tanaka; Chantal Mathieu; Mark Waer; Jacques Pirenne
Addition of steroids blocks the tolerogenic potential of donor-specific blood transfusion.
Transplantation proceedings 2001;33(1-2):375-6.
2001: An D Billiau; Hassan Sefrioui; Lut Overbergh; Omer Rutgeerts; Jozef Goebels; Chantal Mathieu; Mark Waer
Transforming growth factor-beta inhibits lymphokine activated killer cytotoxicity of bone marrow cells: implications for the graft-versus-leukemia effect in irradiation allogeneic bone marrow chimeras.
Transplantation 2001;71(2):292-9.
2000: Conny Gysemans; Mark Waer; Dirk Valckx; JM Laureys; D Mihkalsky; Roger Bouillon; Chantal Mathieu
Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts.
Diabetes 2000;49(12):1992-7.
2000: Brigitte Decallonne; Lut Overbergh; Kristina Casteels; Conny Gysemans; Roger Bouillon; Chantal Mathieu
Streptococcal wall component OK432 restores sensitivity of non-obese diabetic (NOD) thymocytes to apoptotic signals.
Diabetologia 2000;43(10):1302-8.
2000: Conny Gysemans; Mark Waer; JM Laureys; J Depovere; D Pipeleers; Roger Bouillon; Chantal Mathieu
Islet xenograft destruction in the hu-PBL-severe combined immunodeficient (SCID) mouse necessitates anti-CD3 preactivation of human immune cells.
Clinical and experimental immunology 2000;121(3):557-65.
2000: Lut Overbergh; Brigitte Decallonne; Mark Waer; Omer Rutgeerts; Dirk Valckx; Kristina Casteels; JM Laureys; Roger Bouillon; Chantal Mathieu
1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).
Diabetes 2000;49(8):1301-7.
2000: Zhanju Liu; Karel Geboes; Stefaan Colpaert; Lut Overbergh; Chantal Mathieu; Hubertine Heremans; M de Boer; Louis Boon; GR D'Haens; Paul Rutgeerts; Jan L Ceuppens
Prevention of experimental colitis in SCID mice reconstituted with CD45RBhigh CD4+ T cells by blocking the CD40-CD154 interactions.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(11):6005-14.
2000: Evelyne van Etten; Dumitru D Branisteanu; Annemieke Verstuyf; Mark Waer; Roger Bouillon; Chantal Mathieu
Analogs of 1,25-dihydroxyvitamin D3 as dose-reducing agents for classical immunosuppressants.
Transplantation 2000;69(9):1932-42.
2000: Lut Overbergh; Brigitte Decallonne; Dirk Valckx; Annemieke Verstuyf; J Depovere; JM Laureys; Omer Rutgeerts; R Saint-Arnaud; Roger Bouillon; Chantal Mathieu
Identification and immune regulation of 25-hydroxyvitamin D-1-alpha-hydroxylase in murine macrophages.
Clinical and experimental immunology 2000;120(1):139-46.
2000: Annemieke Verstuyf; Lieve Verlinden; Evelyne van Etten; L Shi; Y Wu; C D'Halleweyn; Dirk Van Haver; G D Zhu; Yong-Jun Chen; X Zhou; M R Haussler; Pierre J De Clercq; Maurits Vandewalle; Hugo Van Baelen; Chantal Mathieu; Roger Bouillon
Biological activity of CD-ring modified 1alpha,25-dihydroxyvitamin D analogues: C-ring and five-membered D-ring analogues.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(2):237-52.
2000: Chantal Mathieu; Brigitte Decallonne; Kristina Casteels
[Type 1 diabetes: origin and possibilities for prevention].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 2000;62(5):423-36; discussion 436-7.
1999: Lut Overbergh; Dirk Valckx; Mark Waer; Chantal Mathieu
Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR.
Cytokine 1999;11(4):305-12.
1998: Paul Enzlin; Chantal Mathieu; Dirk Vanderschueren; Koen Demyttenaere
Diabetes mellitus and female sexuality: a review of 25 years' research.
Diabetic medicine : a journal of the British Diabetic Association 1998;15(10):809-15.
1998: Annemieke Verstuyf; Siegfried Segaert; Lieve Verlinden; Kristina Casteels; Roger Bouillon; Chantal Mathieu
Recent developments in the use of vitamin D analogues.
Current opinion in nephrology and hypertension 1998;7(4):397-403.
1998: Kristina Casteels; Conny Gysemans; Mark Waer; Roger Bouillon; JM Laureys; J Depovere; Chantal Mathieu
Sex difference in resistance to dexamethasone-induced apoptosis in NOD mice: treatment with 1,25(OH)2D3 restores defect.
Diabetes 1998;47(7):1033-7.
1998: Kristina Casteels; Mark Waer; JM Laureys; Dirk Valckx; J Depovere; Roger Bouillon; Chantal Mathieu
Prevention of autoimmune destruction of syngeneic islet grafts in spontaneously diabetic nonobese diabetic mice by a combination of a vitamin D3 analog and cyclosporine.
Transplantation 1998;65(9):1225-32.
1998: Kristina Casteels; Mark Waer; Roger Bouillon; J Depovere; Dirk Valckx; JM Laureys; Chantal Mathieu
1,25-Dihydroxyvitamin D3 restores sensitivity to cyclophosphamide-induced apoptosis in non-obese diabetic (NOD) mice and protects against diabetes.
Clinical and experimental immunology 1998;112(2):181-7.
1998: Chantal Mathieu; Kristina Casteels; Mark Waer; JM Laureys; Dirk Valckx; Roger Bouillon
Prevention of diabetes recurrence after syngeneic islet transplantation in NOD mice by analogues of 1,25(OH)2D3 in combination with cyclosporin A: mechanism of action involves an immune shift from Th1 to Th2.
Transplantation proceedings 1998;30(2):541.
1998: Kristina Casteels; Chantal Mathieu; Mark Waer; Dirk Valckx; Lut Overbergh; JM Laureys; Roger Bouillon
Prevention of type I diabetes in nonobese diabetic mice by late intervention with nonhypercalcemic analogs of 1,25-dihydroxyvitamin D3 in combination with a short induction course of cyclosporin A.
Endocrinology 1998;139(1):95-102.
1997: Dumitru D Branisteanu; Chantal Mathieu; Roger Bouillon
Synergism between sirolimus and 1,25-dihydroxyvitamin D3 in vitro and in vivo.
Journal of neuroimmunology 1997;79(2):138-47.
1997: Chantal Mathieu; Kristina Casteels; R Bouillon; Mark Waer
Protection against autoimmune diabetes in mixed bone marrow chimeras: mechanisms involved.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1453-7.
1997: Lieve Verlinden; Annemieke Verstuyf; Chantal Mathieu; B K Tan; Roger Bouillon
Differentiation induction of HL60 cells by 1,25(OH)2D3, all trans retinoic acid, rTGF-beta2 and their combinations.
The Journal of steroid biochemistry and molecular biology 1997;60(1-2):87-97.
1996: Kristina Casteels; Mark Waer; Roger Bouillon; K Allewaert; JM Laureys; Chantal Mathieu
Prevention of type I diabetes by late intervention with nonhypercalcemic analogues of vitamin D3 in combination with cyclosporin A.
Transplantation proceedings 1996;28(6):3095.
1995: Roger Bouillon; Annemieke Verstuyf; Lieve Verlinden; K Allewaert; D Branisteanu; Chantal Mathieu; H van Baelen
Non-hypercalcemic pharmacological aspects of vitamin D analogs.
Biochemical pharmacology 1995;50(5):577-83.
1995: Roger Bouillon; Marjan Garmyn; Annemieke Verstuyf; Siegfried Segaert; Kristina Casteels; Chantal Mathieu
Paracrine role for calcitriol in the immune system and skin creates new therapeutic possibilities for vitamin D analogs.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(1):7-16.
1995: Kristina Casteels; Roger Bouillon; Mark Waer; Chantal Mathieu
Immunomodulatory effects of 1,25-dihydroxyvitamin D3.
Current opinion in nephrology and hypertension 1995;4(4):313-8.
1995: Annemieke Verstuyf; Chantal Mathieu; Lieve Verlinden; Mark Waer; B K Tan; Roger Bouillon
Differentiation induction of human leukemia cells (HL60) by a combination of 1,25-dihydroxyvitamin D3 and retinoic acid (all trans or 9-cis).
The Journal of steroid biochemistry and molecular biology 1995;53(1-6):431-41.
1995: Chantal Mathieu; Mark Waer; Kristina Casteels; JM Laureys; Roger Bouillon
Prevention of type I diabetes in NOD mice by nonhypercalcemic doses of a new structural analog of 1,25-dihydroxyvitamin D3, KH1060.
Endocrinology 1995;136(3):866-72.
1995: Chantal Mathieu; Roger Bouillon; Omer Rutgeerts; Mark Waer
Induction of mixed bone marrow chimerism as potential therapy for autoimmune (type I) diabetes: experience in the NOD model.
Transplantation proceedings 1995;27(1):640-1.
1995: Roger Bouillon; Annemieke Verstuyf; D Branisteanu; Mark Waer; Chantal Mathieu
[Immune modulation by vitamin D analogs in the prevention of autoimmune diseases].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1995;57(5):371-85; discussion 385-7.
1994: Chantal Mathieu; JM Laureys; Mark Waer; Roger Bouillon
Prevention of autoimmune destruction of transplanted islets in spontaneously diabetic NOD mice by KH1060, a 20-epi analog of vitamin D: synergy with cyclosporine.
Transplantation proceedings 1994;26(6):3128-9.
1994: Chantal Mathieu; Roger Bouillon; Omer Rutgeerts; Michel Vandeputte; Mark Waer
Potential role of 1,25(OH)2 vitamin D3 as a dose-reducing agent for cyclosporine and FK 506.
Transplantation proceedings 1994;26(6):3130.
1994: Chantal Mathieu; Mark Waer; JM Laureys; Omer Rutgeerts; Roger Bouillon
Activated form of vitamin D [1,25(OH)2D3] and its analogs are dose-reducing agents for cyclosporine in vitro and in vivo.
Transplantation proceedings 1994;26(5):3048-9.
1994: Chantal Mathieu; B Kuttler; Mark Waer; Roger Bouillon; H J Hahn
Spontaneous reestablishment of self-tolerance in BB/Pfd rats.
Transplantation 1994;58(3):349-54.
1994: Chantal Mathieu; Mark Waer; JM Laureys; Omer Rutgeerts; Roger Bouillon
Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3.
Diabetologia 1994;37(6):552-8.
1994: Chantal Mathieu; Mark Waer; B Kuttler; H J Hahn; Roger Bouillon
Diabetic BB/PFD rats reject MHC incompatible islet grafts, but do not destroy MHC compatible islet grafts.
Transplantation proceedings 1994;26(2):718-9.
1993: Chantal Mathieu; Michel Vandeputte; Roger Bouillon; Mark Waer
Protection against autoimmune diabetes by induction of mixed bone marrow chimerism.
Transplantation proceedings 1993;25(1 Pt 2):1266-7.
1992: Chantal Mathieu; JM Laureys; H Sobis; Michel Vandeputte; Mark Waer; Roger Bouillon
1,25-Dihydroxyvitamin D3 prevents insulitis in NOD mice.
Diabetes 1992;41(11):1491-5.