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Véronique Mathieu

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Igor V Magedov; Véronique Mathieu; Amanda S Peretti; Snezna Rogelj; Laetitia Moreno Y Banuls; Liliya V Frolova; Robert Kiss; Florence Lefranc; Alexander Kornienko
Antiproliferative activity of 2,3-disubstituted indoles toward apoptosis-resistant cancers cells.
Marina Bury; Alessio Cimmino; Antonio Evidente; Olivier Feron; Véronique Mathieu; Véronique Mégalizzi; Bernard Rogister; Anna Andolfi; Robert Kiss
Fusicoccin a, a phytotoxic carbotricyclic diterpene glucoside of fungal origin, reduces proliferation and invasion of glioblastoma cells by targeting multiple tyrosine kinases.
Benjamin Lallemand; Touria Lamkami; Véronique Mathieu; Moustapha Ouedraogo; Nathalie Wauthoz; Karim Amighi; Jacques Dubois; Ivan Jabin; Robert Kiss; Jonathan Goole
Synthesis and plasma pharmacokinetics in CD-1 mice of a 18β-glycyrrhetinic acid derivative displaying anti-cancer activity.

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2013: Igor V Magedov; Véronique Mathieu; Amanda S Peretti; Snezna Rogelj; Laetitia Moreno Y Banuls; Liliya V Frolova; Robert Kiss; Florence Lefranc; Alexander Kornienko
Antiproliferative activity of 2,3-disubstituted indoles toward apoptosis-resistant cancers cells.
Bioorganic & medicinal chemistry letters 2013;23(11):3277-82.
2013: Marina Bury; Alessio Cimmino; Antonio Evidente; Olivier Feron; Véronique Mathieu; Véronique Mégalizzi; Bernard Rogister; Anna Andolfi; Robert Kiss
Fusicoccin a, a phytotoxic carbotricyclic diterpene glucoside of fungal origin, reduces proliferation and invasion of glioblastoma cells by targeting multiple tyrosine kinases.
Translational oncology 2013;6(2):112-23.
2013: Benjamin Lallemand; Touria Lamkami; Véronique Mathieu; Moustapha Ouedraogo; Nathalie Wauthoz; Karim Amighi; Jacques Dubois; Ivan Jabin; Robert Kiss; Jonathan Goole
Synthesis and plasma pharmacokinetics in CD-1 mice of a 18β-glycyrrhetinic acid derivative displaying anti-cancer activity.
The Journal of pharmacy and pharmacology 2013;65(3):402-10.
2013: Gwendoline Van Goietsenoven; Antonio Evidente; Alexander Kornienko; Florence Lefranc; Véronique Mathieu; Robert Kiss
Narciclasine as well as other Amaryllidaceae isocarbostyrils are promising GTP-ase targeting agents against brain cancers.
Medicinal research reviews 2013;33(2):439-55.
2013: M Bury; A Evidente; Philippe Gailly; A Girault; A Kornienko; Véronique Mathieu; V Mégalizzi; Sabine Spiegl-Kreinecker; Christophe Vandier; W Berger; R Kiss
Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity.
Cell death & disease 2013;4():e561.
2013: Véronique Mathieu; Hendrik Niemann; Karim Amighi; Robert Kiss; Florence Lefranc; Nathalie Wauthoz; Peter Proksch
Cyclic versus hemi-bastadins. pleiotropic anti-cancer effects: from apoptosis to anti-angiogenic and anti-migratory effects.
Molecules (Basel, Switzerland) 2013;18(3):3543-61.
2012: Amnat Eamvijarn; Céline Bruyère; Anake Kijjoa; Robert Kiss; Florence Lefranc; Leka Manoch; Véronique Mathieu; Artur Silva; Werner Herz
Secondary metabolites from a culture of the fungus Neosartorya pseudofischeri and their in vitro cytostatic activity in human cancer cells.
Planta medica 2012;78(16):1767-76.
2012: Emmanuel Jean Teinkela Mbosso; Franck Meyer; Silvère Ngouela; Jules Clément Assob Nguedia; Anna Longdoh Njunda; Etienne Tsamo; Dieudonné Adiogo; Pierre Van Antwerpen; Robert Kiss; Benjamin Lallemand; Bruno Ndjakou Lenta; Yvan Looze; Véronique Mathieu; René Wintjens
Ceramide, cerebroside and triterpenoid saponin from the bark of aerial roots of Ficus elastica (Moraceae).
Phytochemistry 2012;83():95-103.
2012: Véronique Mathieu; Thomas Mohr; Françoise Poirier; Jaan Toelen; Gwendoline Van Goietsenoven; Stefaan W Van Gool; Tina Verschuere; Akeila Bellahcène; Caroline Bouzin; Vincent Castronovo; Elisabeth Martin de Lassalle; Steven De Vleeschouwer; zeger debyser; Robert Kiss; Olivier Feron
Galectin-1 in melanoma biology and related neo-angiogenesis processes.
The Journal of investigative dermatology 2012;132(9):2245-54.
2012: Delphine Lamoral-Theys; Florence Lefranc; Véronique Mathieu; Jean Nève; Nathalie Wauthoz; Karim Amighi; Walter Berger; Jacques Dubois; Francois Dufrasne; Philippe Gailly; Petra Heffeter; Utte Jungwirth; Robert Kiss
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release.
Journal of cellular and molecular medicine 2012;16(7):1421-34.
2012: Giovanni Luchetti; Igor V Magedov; Véronique Mathieu; Stephen C Pelly; Mary R Reisenauer; Snezna Rogelj; Willem A L van Otterlo; Anna Andolfi; Cody Champion; Antonio Evidente; Kathryn Hayden; Robert Johnston; Robert Kiss; Delphine Lamoral-Theys; Florence Lefranc; Alexander Kornienko
Bulbispermine: a crinine-type Amaryllidaceae alkaloid exhibiting cytostatic activity toward apoptosis-resistant glioma cells.
ChemMedChem 2012;7(5):815-22.
2012: Véronique Mathieu; Christine Pirker; Wolfgang M Schmidt; Sabine Spiegl-Kreinecker; Michael Grusch; Petra Heffeter; Balazs Hegedus; Robert Kiss; Daniela Lötsch; Walter Berger
Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation.
Oncotarget 2012;3(4):399-413.
2012: A Cimmino; A Evidente; A Kornienko; F Lefranc; Véronique Mathieu; Anna Andolfi; R Kiss
Phenazines and cancer.
Natural product reports 2012;29(4):487-501.
2011: Florence Lefranc; Véronique Mathieu; Robert Kiss
Galectin-1 as an oncotarget in gliomas and melanomas.
Oncotarget 2011;2(12):892-3.
2011: Nikolai M Evdokimov; Antonio Evidente; Liliya V Frolova; Robert Kiss; Delphine Lamoral-Theys; Igor V Magedov; Véronique Mathieu; Stephen C Pelly; Willem A L van Otterlo; Anna Andolfi; Alexander Kornienko
In search of a cytostatic agent derived from the alkaloid lycorine: synthesis and growth inhibitory properties of lycorine derivatives.
Bioorganic & medicinal chemistry 2011;19(23):7252-61.
2011: Benjamin Lallemand; Véronique Mathieu; Martine Prévost; Jean-Paul Becker; Céline Bruyère; Marina Bury; Fabien Chaix; Cédric Delporte; Jacques Dubois; Michel Gelbcke; Jean Ghostin; Ivan Jabin; Robert Kiss
N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity.
Journal of medicinal chemistry 2011;54(19):6501-13.
2011: Florence Lefranc; Véronique Mathieu; Robert Kiss
Galectin-1-mediated biochemical controls of melanoma and glioma aggressive behavior.
World journal of biological chemistry 2011;2(9):193-201.
2011: Benjamin Le Calvé; Gaëlle Lenglet; Véronique Mathieu; Carmen Perrone; Yves Poumay; Pierre Van Antwerpen; Gwendoline Van Goietsenoven; Maurizio Vurro; Maria Chiara Zonno; Anna Andolfi; Marina Bury; Marie-Hélène David-Cordonnier; Sabine Depauw; François Dufrasne; Antonio Evidente; Françoise Herphelin; Benjamin Lallemand; Robert Kiss
In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii.
Toxicology and applied pharmacology 2011;254(1):8-17.
2011: Céline Bruyère; Sébastien Madonna; Gwendoline Van Goietsenoven; Véronique Mathieu; Jean Dessolin; Jean-Louis Kraus; Florence Lefranc; Robert Kiss
JLK1486, a Bis 8-Hydroxyquinoline-Substituted Benzylamine, Displays Cytostatic Effects in Experimental Gliomas through MyT1 and STAT1 Activation and, to a Lesser Extent, PPARγ Activation.
Translational oncology 2011;4(3):126-37.
2011: Gwendoline Van Goietsenoven; Véronique Mathieu; Anna Andolfi; Alessio Cimmino; Florence Lefranc; Robert Kiss; Antonio Evidente
In vitro growth inhibitory effects of cytochalasins and derivatives in cancer cells.
Planta medica 2011;77(7):711-7.
2011: Céline Bruyère; Laurence Abeloos; Delphine Lamoral-Theys; Rebecca Senetta; Véronique Mathieu; Marie Le Mercier; Richard E Kast; Paola Cassoni; Guy Vandenbussche; Robert Kiss; Florence Lefranc
Temozolomide modifies caveolin-1 expression in experimental malignant gliomas in vitro and in vivo.
Translational oncology 2011;4(2):92-100.
2011: Marina Bury; Biancavaleria Punzo; Alexander Berestetskiy; Benjamin Lallemand; Jacques Dubois; Florence Lefranc; Véronique Mathieu; Anna Andolfi; Robert Kiss; Antonio Evidente
Evaluation of the anticancer activities of two fungal polycyclic ethanones, alternethanoxins A and B, and two of their derivatives.
International journal of oncology 2011;38(1):227-32.
2010: Gwendoline Van Goietsenoven; Jenna Hutton; Jean-Paul Becker; Benjamin Lallemand; Francis Robert; Florence Lefranc; Christine Pirker; Guy Vandenbussche; Pierre Van Antwerpen; Antonio Evidente; Walter Berger; Martine Prévost; Jerry Pelletier; Robert Kiss; Terri Goss Kinzy; Alexander Kornienko; Véronique Mathieu
Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(11):4575-84.
2010: Gwendoline Van Goietsenoven; Anna Andolfi; Benjamin Lallemand; Alessio Cimmino; Delphine Lamoral-Theys; T Gras; Amina Abou-Donia; Jacques Dubois; Florence Lefranc; Véronique Mathieu; Alexander Kornienko; Robert Kiss; Antonio Evidente
Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells.
Journal of natural products 2010;73(7):1223-7.
2010: ElHadj Saidou Balde; Anna Andolfi; Céline Bruyère; Alessio Cimmino; Delphine Lamoral-Theys; Maurizio Vurro; Marc Van Damme; Claudio Altomare; Véronique Mathieu; Robert Kiss; Antonio Evidente
Investigations of fungal secondary metabolites with potential anticancer activity.
Journal of natural products 2010;73(5):969-71.
2010: Nathalie Wauthoz; Philippe Deleuze; Julien Hecq; Isabelle Roland; Sven Saussez; Ivan Adanja; Olivier Debeir; Christine Decaestecker; Véronique Mathieu; Robert Kiss; Karim Amighi
In vivo assessment of temozolomide local delivery for lung cancer inhalation therapy.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(5):402-11.
2010: D Lamoral-Theys; Christine Decaestecker; Véronique Mathieu; J Dubois; A Kornienko; Robert Kiss; A Evidente; L Pottier
Lycorine and its derivatives for anticancer drug design.
Mini reviews in medicinal chemistry 2010;10(1):41-50.
2010: Marie Le Mercier; Shannon Fortin; Véronique Mathieu; Robert Kiss; Florence Lefranc
Galectins and gliomas.
Brain pathology (Zurich, Switzerland) 2010;20(1):17-27.
2009: Delphine Lamoral-Theys; Anna Andolfi; Gwendoline Van Goietsenoven; Alessio Cimmino; Benjamin Le Calvé; Nathalie Wauthoz; Véronique Mégalizzi; Thierry Gras; Céline Bruyère; Jacques Dubois; Véronique Mathieu; Alexander Kornienko; Robert Kiss; Antonio Evidente
Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight.
Journal of medicinal chemistry 2009;52(20):6244-56.
2009: Fraczek Joanna; Leo van Grunsven; Véronique Mathieu; Snykers Sarah; Deleu Sarah; Vanderkerken Karin; Vanhaecke Tamara; Rogiers Vera
Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology.
Journal of cellular and molecular medicine 2009;13(9B):2990-3005.
2009: Véronique Mathieu; Christine Pirker; Elisabeth Martin De Lassalle; Mathieu Vernier; Tatjana Mijatovic; Nancy DeNeve; Jean-François Gaussin; Mischael Dehoux; Florence Lefranc; Walter Berger; Robert Kiss
The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment.
Journal of cellular and molecular medicine 2009;13(9B):3960-72.
2009: Florence Lefranc; Sébastien Sauvage; Gwendoline Van Goietsenoven; Véronique Mégalizzi; Delphine Lamoral-Theys; Olivier Debeir; Sabine Spiegl-Kreinecker; Walter Berger; Véronique Mathieu; Christine Decaestecker; Robert Kiss
Narciclasine, a plant growth modulator, activates Rho and stress fibers in glioblastoma cells.
Molecular cancer therapeutics 2009;8(7):1739-50.
2009: Marie Le Mercier; Shannon Fortin; Véronique Mathieu; Isabelle Roland; Sabine Spiegl-Kreinecker; Benjamin Haibe-Kains; Gianluca Bontempi; Christine Decaestecker; Walter Berger; Florence Lefranc; Robert Kiss
Galectin 1 proangiogenic and promigratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression.
Neoplasia (New York, N.Y.) 2009;11(5):485-96.
2009: Hannelore Denys; Geert Braems; Kathleen Lambein; Patrick Pauwels; An Hendrix; Astrid De Boeck; Véronique Mathieu; Marc Bracke; Olivier De Wever
The extracellular matrix regulates cancer progression and therapy response: implications for prognosis and treatment.
Current pharmaceutical design 2009;15(12):1373-84.
2008: Véronique Mathieu; Nancy De Nève; Marie Le Mercier; Janique Dewelle; Jean-François Gaussin; Mischael Dehoux; Robert Kiss; Florence Lefranc
Combining bevacizumab with temozolomide increases the antitumor efficacy of temozolomide in a human glioblastoma orthotopic xenograft model.
Neoplasia (New York, N.Y.) 2008;10(12):1383-92.
2008: Marie Le Mercier; Florence Lefranc; Tatjana Mijatovic; Olivier Debeir; Benjamin Haibe-Kains; Gianluca Bontempi; Christine Decaestecker; Robert Kiss; Véronique Mathieu
Evidence of galectin-1 involvement in glioma chemoresistance.
Toxicology and applied pharmacology 2008;229(2):172-83.
2008: Tatjana Mijatovic; Nancy De Nève; Philippe Gailly; Véronique Mathieu; Benjamin Haibe-Kains; Gianluca Bontempi; Javier Lapeira; Christine Decaestecker; Vincenzo Facchini; Robert Kiss
Nucleolus and c-Myc: potential targets of cardenolide-mediated antitumor activity.
Molecular cancer therapeutics 2008;7(5):1285-96.
2008: Marie Le Mercier; Véronique Mathieu; Benjamin Haibe-Kains; Gianluca Bontempi; Tatjana Mijatovic; Christine Decaestecker; Robert Kiss; Florence Lefranc
Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses.
Journal of neuropathology and experimental neurology 2008;67(5):456-69.
2007: Véronique Mathieu; Marie Le Mercier; Nancy De Neve; Sébastien Sauvage; Thierry Gras; Isabelle Roland; Florence Lefranc; Robert Kiss
Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model.
The Journal of investigative dermatology 2007;127(10):2399-410.
2007: Véronique Mégalizzi; Véronique Mathieu; Tatjana Mijatovic; Philippe Gailly; Olivier Debeir; Nancy De Neve; Marc Van Damme; Gianluca Bontempi; Benjamin Haibe-Kains; Christine Decaestecker; Yasuko Kondo; Robert Kiss; Florence Lefranc
4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Neoplasia (New York, N.Y.) 2007;9(5):358-69.
2007: Tatjana Mijatovic; Philippe Gailly; Véronique Mathieu; Nancy De Nève; Paul Yeaton; Robert Kiss; Christine Decaestecker
Neurotensin is a versatile modulator of in vitro human pancreatic ductal adenocarcinoma cell (PDAC) migration.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(4):315-26.
2006: Tatjana Mijatovic; Véronique Mathieu; Jean-François Gaussin; Nancy De Nève; Fabrice Ribaucour; Eric Van Quaquebeke; Patrick Dumont; Francis Darro; Robert Kiss
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.
Neoplasia (New York, N.Y.) 2006;8(5):402-12.
2006: Laurent Ingrassia; Isabelle Camby; Florence Lefranc; Véronique Mathieu; Prosper Nshimyumukiza; Francis Darro; Robert Kiss
Anti-galectin compounds as potential anti-cancer drugs.
Current medicinal chemistry 2006;13(29):3513-27.
2005: Véronique Mathieu; Tatjana Mijatovic; Marc Van Damme; Robert Kiss
Gastrin exerts pleiotropic effects on human melanoma cell biology.
Neoplasia (New York, N.Y.) 2005;7(10):930-43.
2004: Florence Lefranc; Tatjana Mijatovic; Véronique Mathieu; Sandrine Rorive; Christine Decaestecker; Olivier Debeir; Jacques Brotchi; Philippe Van Ham; Isabelle Salmon; Robert Kiss
Characterization of gastrin-induced proangiogenic effects in vivo in orthotopic U373 experimental human glioblastomas and in vitro in human umbilical vein endothelial cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8250-65.