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Hisahiro Matsubara

Research Profile

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Genes, p53

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Tumor Cell Line

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Yasunori Akutsu; Daisuke Horibe; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Tetsuro Maruyama; Testutaro Sazuka; Kiyohiko Shuto; Nobuyoshi Takeshita; Masaya Uesato; Naoki Akanuma; Hisahiro Matsubara
The overall prevalence of metastasis in t1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients.
Isamu Hoshino; Hisahiro Matsubara
MicroRNAs in cancer diagnosis and therapy: from bench to bedside.
Naoki Akanuma; Yasunori Akutsu; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Tetsuro Maruyama; Asami Sato; Toru Shiratori; Kiyohiko Shuto; Nobuyoshi Takeshita; Masaya Uesato; Hisahiro Matsubara
Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case.

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2013: Yasunori Akutsu; Daisuke Horibe; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Tetsuro Maruyama; Testutaro Sazuka; Kiyohiko Shuto; Nobuyoshi Takeshita; Masaya Uesato; Naoki Akanuma; Hisahiro Matsubara
The overall prevalence of metastasis in t1 esophageal squamous cell carcinoma: a retrospective analysis of 295 patients.
Annals of surgery 2013;257(6):1032-8.
2013: Isamu Hoshino; Hisahiro Matsubara
MicroRNAs in cancer diagnosis and therapy: from bench to bedside.
Surgery today 2013;43(5):467-78.
2013: Naoki Akanuma; Yasunori Akutsu; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Tetsuro Maruyama; Asami Sato; Toru Shiratori; Kiyohiko Shuto; Nobuyoshi Takeshita; Masaya Uesato; Hisahiro Matsubara
Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case.
Surgery today 2013;43(4):446-51.
2013: Nobuyoshi Takeshita; Masaya Uesato; Yukimasa Miyazawa; Toru Shiratori; Kiyohiko Shuto; Yasunori Akutsu; Isamu Hoshino; Tsuguaki Kono; Hisahiro Matsubara
[A case of far advanced-esophageal squamous cell carcinoma successfully treated with docetaxel].
Gan to kagaku ryoho. Cancer & chemotherapy 2013;40(2):233-5.
2013: Toshiko Kajiwara; Hisahiro Matsubara; Masafumi Matsuo; Kazuyuki Matsushita; Hideaki Shimada; Mai Tamura; Nobuko Tanaka; Takeshi Tomonaga; Yasuaki Habara; Sakae Itoga; Fumio Nomura
SAP155-mediated c-myc suppressor far-upstream element-binding protein-interacting repressor splicing variants are activated in colon cancer tissues.
Cancer science 2013;104(2):149-56.
2013: Yasunori Akutsu; Toshiharu Hanaoka; Isamu Hoshino; Tsuguaki Kono; Kazuo Narushima; Wei Qin; Yoshihide Semba; Toru Tochigi; Masaya Uesato; Hisahiro Matsubara
S-1 monotherapy as second- or third-line chemotherapy for unresectable and recurrent esophageal squamous cell carcinoma.
Oncology 2013;84(5):305-10.
2012: Akiko Suganami; Taro Toyota; Yasunori Akutsu; Akira Aoki; Hideki Hayashi; H Kawahira; Tomoyuki Madono; Hisahiro Matsubara; Katsuhiko Miyamoto; Yutaka Muraki; Shigetoshi Okazaki; Takashige Omatsu; Kengo Saito; Hiroshi Shirasawa; Yutaka Tamura
Preparation and characterization of phospholipid-conjugated indocyanine green as a near-infrared probe.
Bioorganic & medicinal chemistry letters 2012;22(24):7481-5.
2012: Yasunori Akutsu; Satoshi Endo; Takeshi Fujishiro; Isamu Hoshino; Shunsuke Imanishi; Tsuguaki Kono; Kentaro Murakami; Takeshi Toyozumi; Masaya Uesato; Hisahiro Matsubara
Are additional trace elements necessary in total parenteral nutrition for patients with esophageal cancer receiving cisplatin-based chemotherapy?
Biological trace element research 2012;150(1-3):109-15.
2012: Gaku Ohira; Kiyohiko Shuto; Tohru Tochigi; Takayuki Tohma; Takeshi Fujishiro; Hisashi Gunji; Toshiharu Hanaoka; Naoyuki Hanari; Shunsuke Imanishi; Tsuguaki Kono; Hisahiro Matsubara; Hideaki Miyauchi; Kazuo Narushima; Noriyuki Yanagawa
Utility of arterial phase of dynamic CT for detection of intestinal ischemia associated with strangulation ileus.
World journal of radiology 2012;4(11):450-4.
2012: Gaku Ohira; Kazufumi Suzuki; Takayuki Tohma; Hideaki Miyauchi; Takanori Nishimori; Hisahiro Matsubara
[Neoadjuvant chemotherapy for recurrent colorectal cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2012;39(12):2189-91.
2012: Nobuyoshi Takeshita; Yasuo Yoneyama; Yukimasa Miyazawa; Mikito Mori; Naoki Akanuma; Yasunori Akutsu; Naoyuki Hanari; Isamu Hoshino; Norimasa Ikeda; Yuka Isozaki; Masayuki Kano; Tetsurou Maruyama; Hisahiro Matsubara
miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1.
International journal of oncology 2012;41(5):1653-61.
2012: Yasunori Akutsu; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Yukimasa Miyazawa; Toru Shiratori; Kiyohiko Shuto; Masaya Uesato; Naoki Akanuma; Hisahiro Matsubara
A phase 1/11 study of second-line chemotherapy with fractionated docetaxel and nedaplatin for 5-FU/cisplatin-resistant esophageal squamous cell carcinoma.
Hepato-gastroenterology 2012;59(119):2095-8.
2012: Yuka Isozaki; Takashi Kinoshita; Tetsuro Maruyama; Naoki Akanuma; Yasunori Akutsu; Naoyuki Hanari; Isamu Hoshino; Mikito Mori; Norikazu Nishino; Nijiro Nohata; Naohiko Seki; Nobuyoshi Takeshita; Yasuo Yoneyama; Minoru Yoshida; Hisahiro Matsubara
Identification of novel molecular targets regulated by tumor suppressive miR-375 induced by histone acetylation in esophageal squamous cell carcinoma.
International journal of oncology 2012;41(3):985-94.
2012: Akihiro Usui; Yasunori Akutsu; Isamu Hoshino; Masayuki Kano; Kentaro Murakami; Takanori Nishimori; Haruhito Sakata; Kiyohiko Shuto; Hisahiro Matsubara
The molecular role of Fra-1 and its prognostic significance in human esophageal squamous cell carcinoma.
Cancer 2012;118(13):3387-96.
2012: Yasunori Akutsu; Isamu Hoshino; Yuka Isozaki; Tsuguaki Kono; Toru Shiratori; Kiyohiko Shuto; Masaya Uesato; Takashi Uno; Naoki Akanuma; Hisahiro Matsubara
The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma.
Journal of surgical oncology 2012;105(8):756-60.
2012: Yasunori Akutsu; Yosuke Izumi; Tadashi Kamada; Matsuo Nagata; Yukio Nakatani; Shinichi Okazumi; Hideaki Shimada; Hirohiko Tsujii; Shigeru Yamada; Shigeo Yasuda; Hisahiro Matsubara
A phase I/II clinical trial of preoperative short-course carbon-ion radiotherapy for patients with squamous cell carcinoma of the esophagus.
Journal of surgical oncology 2012;105(8):750-5.
2012: Kazuyuki Matsushita; Tohru Natsume; Akihiro Ito; Toshiko Kajiwara; Shuji Kubo; David Levens; Hisahiro Matsubara; Mamoru Satoh; Hideaki Shimada; Mai Tamura; Nobuko Tanaka; Takeshi Tomonaga; Minoru Yoshida; Rei Yoshimoto; Fumio Nomura
SAP155-mediated splicing of FUSE-binding protein-interacting repressor serves as a molecular switch for c-myc gene expression.
Molecular cancer research : MCR 2012;10(6):787-99.
2012: Tomoyoshi Aoyagi; Kohichi Hayano; Toshiki Kazama; Yoshihiro Nabeya; Shinichi Okazumi; Hiroshige Saitoh; Asami Satoh; Hideaki Shimada; Kiyohiko Shuto; Hisahiro Matsubara
Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis.
European radiology 2012;22(6):1172-7.
2012: Jurat Obul; Kenichi Sato; Emi Utsuno; Maynur Abliz; Takayuki Ishige; Sakae Itoga; Hisahiro Matsubara; Kazuyuki Matsushita; Fumio Nomura
High-resolution melting analyses for gene scanning of APC, MLH1, MSH2, and MSH6 associated with hereditary colorectal cancer.
Genetic testing and molecular biomarkers 2012;16(5):406-11.
2012: H Kawahira; Takashi Akai; Hiromichi Aoyama; Naoyuki Hanari; Hideki Hayashi; Daisuke Horibe; Mikito Mori; Yoshihiro Nabeya; Toshiyuki Natsume; Kiyohiko Shuto; Masaya Uesato; Hisahiro Matsubara
Surgical advantages of gastric SMTs by laparoscopy and endoscopy cooperative surgery.
Hepato-gastroenterology 2012;59(114):415-7.
2011: Takeshi Tanaka; Shuang Wu; Makoto Arai; Fumio Imazeki; Tatsuo Kanda; Hisahiro Matsubara; Hideaki Miyauchi; Osamu Yokosuka
Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer.
Oncology reports 2011;26(5):1329-35.
2011: Yasunori Akutsu; Satoshi Endo; Naoyuki Hanari; Norimasa Ikeda; Aki Komatsu-Akimoto; Yukimasa Miyazawa; Mikito Mori; Yasuo Yoneyama; Gulbostan Yusup; Hisahiro Matsubara
COX2 expression predicts resistance to chemoradiotherapy in esophageal squamous cell carcinoma.
Annals of surgical oncology 2011;18(10):2946-51.
2011: Yasunori Akutsu; Hisahiro Matsubara
The significance of lymph node status as a prognostic factor for esophageal cancer.
Surgery today 2011;41(9):1190-5.
2011: Yasunori Akutsu; Hisahiro Matsubara
[Heavy ion radiotherapy for esophageal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 6():358-62.
2011: Hisahiro Matsubara
[Treatment strategy for thoracic esophageal cancer].
Nihon rinsho. Japanese journal of clinical medicine 2011;69 Suppl 6():218-22.
2011: Yoshihiro Nabeya; Takenori Ochiai; Motohiro Ohkoshi; Takao Suzuki; Masaki Takiguchi; Aki Furuya; Naoki Koide; Hisahiro Matsubara; Takaki Hiwasa
Calpain regulates thymidylate synthase-5-fluoro-dUMP complex levels associated with response to 5-fluorouracil in gastric cancer cells.
Cancer science 2011;102(8):1509-15.
2011: Atsushi Kitamura; David Levens; Hisahiro Matsubara; Kazuyuki Matsushita; Mamoru Hasegawa; Kenzo Hiroshima; Makoto Inoue; Yasunori Sato; Hideaki Shimada; Yuji Tada; Masatoshi Tagawa; Yuichi Takiguchi; Koichiro Tatsumi; Takeshi Tomonaga; Makako Yamanaka; Fumio Nomura
Synergistic effect of non-transmissible Sendai virus vector encoding the c-myc suppressor FUSE-binding protein-interacting repressor plus cisplatin in the treatment of malignant pleural mesothelioma.
Cancer science 2011;102(7):1366-73.
2011: Toshiyuki Natsume; Kiyohiko Shuto; Noriyuki Yanagawa; Takashi Akai; H Kawahira; Hideki Hayashi; Hisahiro Matsubara
The classification of anatomic variations in the perigastric vessels by dual-phase CT to reduce intraoperative bleeding during laparoscopic gastrectomy.
Surgical endoscopy 2011;25(5):1420-4.
2011: H Kawahira; Takashi Akai; Takehide Asano; Hideki Hayashi; Daisuke Horibe; Akinao Matsunaga; Fumihiko Miura; Hideaki Miyauchi; Yoshihiro Nabeya; Toshiyuki Natsume; Kenichi Saigo; Kiyohiko Shuto; Kazufumi Suzuki; Hisahiro Matsubara
Survival predictors of patients with primary duodenal adenocarcinoma.
International surgery 2011;96(2):111-6.
2011: Toshiyuki Natsume; Fumio Nomura; Kiyohiko Shuto; Kazuyuki Matsushita; Yoshihiro Nabeya; Takashi Akai; Yasunori Akutsu; Hideki Hayashi; Daisuke Horibe; H Kawahira; Hisahiro Matsubara
Low peritoneal and systemic inflammatory response after laparoscopy-assisted gastrectomy compared to open gastrectomy.
Hepato-gastroenterology 2011;58(106):659-62.
2011: Yasunori Akutsu; Hisahiro Matsubara; Masayuki Kano; Akihiro Usui; Yasuo Yoneyama; Norimasa Ikeda; Aki Komatsu; Gulbostan Yusup
Correlation between gp96 expression and the surgical outcome in patients with esophageal squamous cell carcinoma.
Annals of surgical oncology 2011;18(3):832-7.
2011: Di Wu; Kazuyuki Matsushita; Hisahiro Matsubara; Fumio Nomura; Takeshi Tomonaga
An alternative splicing isoform of eukaryotic initiation factor 4H promotes tumorigenesis in vivo and is a potential therapeutic target for human cancer.
International journal of cancer. Journal international du cancer 2011;128(5):1018-30.
2011: Kazufumi Suzuki; Hisahiro Matsubara
Recent advances in p53 research and cancer treatment.
Journal of biomedicine & biotechnology 2011;2011():978312.
2011: Tomoyoshi Aoyagi; Toshiki Kazama; Shinichi Okazumi; Hideaki Shimada; Kiyohiko Shuto; Hisahiro Matsubara
Apparent diffusion coefficient values measured by diffusion-weighted imaging predict chemoradiotherapeutic effect for advanced esophageal cancer.
Digestive surgery 2011;28(4):252-7.
2010: Masayuki Kano; Naohiko Seki; Naoko Kikkawa; Lisa Fujimura; Isamu Hoshino; Yasunori Akutsu; Takeshi Chiyomaru; Hideki Enokida; Masayuki Nakagawa; Hisahiro Matsubara
miR-145, miR-133a and miR-133b: Tumor-suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2010;127(12):2804-14.
2010: Kiyohiko Shuto; Gaku Ohira; Tsuguaki Kono; Toshiyuki Natsume; Takayuki Tohma; Asami Sato; Takumi Ota; Hiroshige Saito; Yasunori Akutsu; Masaya Uesato; Hisahiro Matsubara; Shinichi Okazumi; Takehito Kaiho
[Regional treatment of esophageal liver metastasis by intra-arterial low-dose 5-FU therapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(12):2409-11.
2010: Hiroshige Saito; Kiyohiko Shuto; Takumi Ota; Takayuki Toma; Gaku Ohira; Toshiyuki Natsume; Masaya Uesato; Yasunori Akutsu; Tsuguaki Kono; Hisahiro Matsubara
[A case of long-term survival after resection for postoperative solitary adrenal metastasis from esophageal adenocarcinoma].
Gan to kagaku ryoho. Cancer & chemotherapy 2010;37(12):2406-8.
2010: Hisahiro Matsubara
[Pre- and postoperative nutritional support in upper disgestive tract surgery].
Nihon Geka Gakkai zasshi 2010;111(6):358-62.
2010: Masaya Uesato; Yoshihiro Nabeya; Shinichi Miyazaki; Taito Aoki; Takashi Akai; Kiyohiko Shuto; Tohru Tanizawa; Masaru Miyazaki; Hisahiro Matsubara
Postoperative recurrence of an IPMN of the pancreas with a fistula to the stomach.
World journal of gastrointestinal endoscopy 2010;2(10):349-51.
2010: Isamu Hoshino; Hisahiro Matsubara
Recent advances in histone deacetylase targeted cancer therapy.
Surgery today 2010;40(9):809-15.
2010: Masaya Uesato; Yoshihiro Nabeya; Takashi Akai; Masahito Inoue; Yoshiyuki Watanabe; H Kawahira; Toshitaka Mamiya; Yoshihito Ohta; Ryuji Motojima; Akiko Kagaya; Yorihiko Muto; Hideki Hayashi; Hisahiro Matsubara
Salivary amylase activity is useful for assessing perioperative stress in response to pain in patients undergoing endoscopic submucosal dissection of gastric tumors under deep sedation.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2010;13(2):84-9.
2010: Tomoyoshi Aoyagi; Kiyohiko Shuto; Shinichi Okazumi; Hidesato Miyauchi; Toshiki Kazama; Hisahiro Matsubara
Evaluation of ulcerative colitis using diffusion-weighted imaging.
Hepato-gastroenterology 2010;57(99-100):468-71.
2010: Yasunori Akutsu; Hisahiro Matsubara; Kiyohiko Shuto; Tooru Shiratori; Masaya Uesato; Yukimasa Miyazawa; Isamu Hoshino; Kentaro Murakami; Akihiro Usui; Masayuki Kano; Hideaki Miyauchi
Pre-operative dental brushing can reduce the risk of postoperative pneumonia in esophageal cancer patients.
Surgery 2010;147(4):497-502.
2010: Asami Satoh; Kiyohiko Shuto; Shinichi Okazumi; Gaku Ohira; Toshiyuki Natsume; Koichi Hayano; Kazuo Narushima; Hiroshige Saito; Takumi Ohta; Yoshihiro Nabeya; Noriyuki Yanagawa; Hisahiro Matsubara
Role of perfusion CT in assessing tumor blood flow and malignancy level of gastric cancer.
Digestive surgery 2010;27(4):253-60.
2010: Kentaro Murakami; Hisahiro Matsubara; Isamu Hoshino; Yasunori Akutsu; Yukimasa Miyazawa; Kazuyuki Matsushita; Haruhito Sakata; Takanori Nishimori; Akihiro Usui; Masayuki Kano; Norikazu Nishino; Minoru Yoshida
CHAP31 induces apoptosis only via the intrinsic pathway in human esophageal cancer cells.
Oncology 2010;78(1):62-74.
2010: H Kawahira; Kazuyuki Matsushita; Tooru Shiratori; Takanori Shimizu; Yoshihiro Nabeya; Hideki Hayashi; Takenori Ochiai; Hisahiro Matsubara; Hideaki Shimada
Viral shedding after p53 adenoviral gene therapy in 10 cases of esophageal cancer.
Cancer science 2010;101(1):289-91.
2009: Kiyohiko Shuto; Hiroshige Saito; Gaku Ohira; Toshiyuki Natsume; Tsuguaki Kono; Takayuki Tohma; Asami Sato; Takumi Ota; Yasunori Akutsu; Tomoyoshi Aoyagi; Hisahiro Matsubara
[Diffusion-weighted MR imaging for postoperative nodal recurrence of esophageal squamous cell cancer in comparison with FDG-PET].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2468-70.
2009: Hiroshige Saito; Kiyohiko Shuto; Gaku Ohira; Toshiyuki Natsume; Kazuo Narushima; Asami Sato; Takumi Ota; Haruto Sakata; Hidetoshi Miyauchi; Hisahiro Matsubara
[Evaluation of preoperative chemoradiation therapy for lower rectal carcinoma using DWIBS].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2146-8.
2009: Takumi Ota; Kiyohiko Shuto; Gaku Ohira; Toshiyuki Natsume; Hiroshige Saito; Asami Sato; H Kawahira; Yoshihiro Nabeya; Hisahiro Matsubara
[Evaluation of hepatic arterial infusion chemotherapy for liver metastasis from gastric cancer].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):2019-21.
2009: Masayuki Kano; Yoshihiro Nabeya; Yasunori Akutsu; Kiyohiko Shuto; Masaya Uesato; Yukimasa Miyazawa; Hisahiro Matsubara
[Effect of practical use of preoperative immunonutrition with impact on prevention of postoperative pneumonia after esophagectomy].
Gan to kagaku ryoho. Cancer & chemotherapy 2009;36(12):1958-60.
2009: Masayuki Kano; Shigeru Yamada; Isamu Hoshino; Kentaro Murakami; Yasunori Akutsu; Haruhito Sakata; Takanori Nishimori; Akihiro Usui; Yukimasa Miyazawa; Tadashi Kamada; Hirohiko Tsujii; Hisahiro Matsubara
Effects of carbon-ion radiotherapy combined with a novel histone deacetylase inhibitor, cyclic hydroxamic-acid-containing peptide 31 in human esophageal squamous cell carcinoma.
Anticancer research 2009;29(11):4433-8.
2009: Yasunori Akutsu; Hisahiro Matsubara
Perioperative management for the prevention of postoperative pneumonia with esophageal surgery.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 2009;15(5):280-5.
2009: Koichi Hayano; Kiyohiko Shuto; Keiji Koda; Noriyuki Yanagawa; Shinichi Okazumi; Hisahiro Matsubara
Quantitative measurement of blood flow using perfusion CT for assessing clinicopathologic features and prognosis in patients with rectal cancer.
Diseases of the colon and rectum 2009;52(9):1624-9.
2009: Hisako Motani-Saitoh; Hiroyuki Inoue; Tohru Tanizawa; Yoshihiro Nabeya; Daisuke Yajima; Mutsumi Hayakawa; Yayoi Sato; Yukio Nakatani; Hisahiro Matsubara; Hirotaro Iwase
Useful DNA typing using AmpFlSTR Identifiler Kit for formaldehyde-fixed paraffin-embedded (FFPE) tissues in early gastric cancer patient with lymph node metastasis.
Histology and histopathology 2009;24(9):1139-45.
2009: Hideaki Shimada; Shinichi Okazumi; Tooru Shiratori; Yasunori Akutsu; Hisahiro Matsubara
Impact of lymph node involvement in T2 or T3 thoracic esophageal squamous cell carcinoma.
Hepato-gastroenterology 2009;56(93):1039-43.
2009: Yasunori Akutsu; Hisahiro Matsubara; Kiyohiko Shuto; Masaya Uesato; Mikito Mori; Isamu Hoshino; Tooru Shiratori; Yukimasa Miyazawa; Hisao Ito; Takashi Uno
Clinical and pathologic evaluation of the effectiveness of neoadjuvant chemoradiation therapy in advanced esophageal cancer patients.
World journal of surgery 2009;33(5):1002-9.
2009: Takaki Hiwasa; Hideaki Shimada; Mari Kuboshima; Tooru Shiratori; Akiko Kagaya; Yoshihiro Nabeya; Sumio Sugano; Takenori Ochiai; Hisahiro Matsubara; Masaki Takiguchi
Decrease in chemosensitivity against anticancer drugs by an esophageal squamous cell carcinoma SEREX antigen, AISEC.
International journal of oncology 2009;34(3):641-8.
2009: Hideaki Shimada; Tooru Shiratori; Mari Yasuraoka; Akiko Kagaya; Mari Kuboshima; Fumio Nomura; Masaki Takiguchi; Takenori Ochiai; Hisahiro Matsubara; Takaki Hiwasa
Identification of Makorin 1 as a novel SEREX antigen of esophageal squamous cell carcinoma.
BMC cancer 2009;9():232.
2009: Kazuyuki Matsushita; Takeshi Tomonaga; Toshiko Kajiwara; Hideaki Shimada; Sakae Itoga; Takaki Hiwasa; Shuji Kubo; Takenori Ochiai; Hisahiro Matsubara; Fumio Nomura
c-myc suppressor FBP-interacting repressor for cancer diagnosis and therapy.
Frontiers in bioscience : a journal and virtual library 2009;14():3401-8.
2008: Isamu Hoshino; Hisahiro Matsubara; Yasunori Akutsu; Takanori Nishimori; Yasuo Yoneyama; Kentaro Murakami; Haruhito Sakata; Kazuyuki Matsushita; Aki Komatsu; Ryan Brooks; Takenori Ochiai
Role of histone deacetylase inhibitor in adenovirus-mediated p53 gene therapy in esophageal cancer.
Anticancer research 2008;28(2A):665-71.
2008: Hideaki Shimada; Hisahiro Matsubara; Shinichi Okazumi; Kaichi Isono; Takenori Ochiai
Improved surgical results in thoracic esophageal squamous cell carcinoma: a 40-year analysis of 792 patients.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(3):518-26.
2008: Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Tooru Shiratori; Yasunori Akutsu; Yoshihiro Nabeya; Tooru Tanizawa; Kazuyuki Matsushita; Hideaki Hayashi; Kaichi Isono; Takenori Ochiai
Long-term results after dissection of positive thoracic lymph nodes in patients with esophageal squamous cell carcinoma.
World journal of surgery 2008;32(2):255-61.
2008: Isamu Hoshino; Hisahiro Matsubara; Aki Komatsu; Yasunori Akutsu; Takanori Nishimori; Yasuo Yoneyama; Kentaro Murakami; Haruhito Sakata; Kazuyuki Matsushita; Yukimasa Miyazawa; Ryan Brooks; Minoru Yoshida; Takenori Ochiai
Combined effects of p53 gene therapy and leptomycin B in human esophageal squamous cell carcinoma.
Oncology 2008;75(1-2):113-9.
2008: Yoshihito Ohta; Kohji Saitoh; Takashi Akai; Masaya Uesato; Takenori Ochiai; Hisahiro Matsubara
Early primary duodenal carcinoma arising from Brunner's glands synchronously occurring with sigmoid colon carcinoma: report of a case.
Surgery today 2008;38(8):756-60.
2008: Yasunori Akutsu; Hisahiro Matsubara; Shinichi Okazumi; Hideaki Shimada; Kiyohiko Shuto; Tooru Shiratori; Takenori Ochiai
Impact of preoperative dental plaque culture for predicting postoperative pneumonia in esophageal cancer patients.
Digestive surgery 2008;25(2):93-7.
2008: Hideaki Shimada; Tooru Shiratori; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Kiyohiko Shuto; Yasunori Akutsu; Hideki Hayashi; Kaichi Isono; Takenori Ochiai
Have surgical outcomes of pathologic T4 esophageal squamous cell carcinoma really improved? Analysis of 268 cases during 45 years of experience.
Journal of the American College of Surgeons 2008;206(1):48-56.
2007: Kentaro Murakami; Haruhito Sakata; Yukimasa Miyazawa; Kazuyuki Matsushita; Yasunori Akutsu; Takanori Nishimori; Yasuo Yoneyama; Akihiro Usui; Masayuki Kano; Hisahiro Matsubara; Takenori Ochiai
[Two cases treated with trastuzumab as primary chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy 2007;34(10):1683-7.
2007: Koichi Hayano; Shinichi Okazumi; Kiyohiko Shuto; Hisahiro Matsubara; Hideaki Shimada; Yoshihiro Nabeya; Toshiki Kazama; Noriyuki Yanagawa; Takenori Ochiai
Perfusion CT can predict the response to chemoradiation therapy and survival in esophageal squamous cell carcinoma: initial clinical results.
Oncology reports 2007;18(4):901-8.
2007: Isamu Hoshino; Hisahiro Matsubara; Yasunori Akutsu; Takanori Nishimori; Yasuo Yoneyama; Kentaro Murakami; Haruhito Sakata; Kazuyuki Matsushita; Takenori Ochiai
Tumor suppressor Prdx1 is a prognostic factor in esophageal squamous cell carcinoma patients.
Oncology reports 2007;18(4):867-71.
2007: Isamu Hoshino; Hisahiro Matsubara; Yasunori Akutsu; Takanori Nishimori; Yasuo Yoneyama; Kentaro Murakami; Aki Komatsu; Haruhito Sakata; Kazuyuki Matsushita; Takenori Ochiai
Gene expression profiling induced by histone deacetylase inhibitor, FK228, in human esophageal squamous cancer cells.
Oncology reports 2007;18(3):585-92.
2007: Yasunori Akutsu; Hisahiro Matsubara; Tetsuro Urashima; Aki Komatsu; Haruhito Sakata; Takanori Nishimori; Yasuo Yoneyama; Isamu Hoshino; Kentaro Murakami; Akihiro Usui; Masayuki Kano; Takenori Ochiai
Combination of direct intratumoral administration of dendritic cells and irradiation induces strong systemic antitumor effect mediated by GRP94/gp96 against squamous cell carcinoma in mice.
International journal of oncology 2007;31(3):509-15.
2007: Naoyuki Hanari; Hisahiro Matsubara; Isamu Hoshino; Yasunori Akutsu; Takanori Nishimori; Kenataro Murakami; Haruhito Sakata; Yukimasa Miyazawa; Takenori Ochiai
Combinatory gene therapy with electrotransfer of midkine promoter-HSV-TK and interleukin-21.
Anticancer research 2007;27(4B):2305-10.
2007: Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Tooru Shiratori; Hideki Hayashi; Kiyohiko Shuto; Yasunori Akutsu; Takenori Ochiai
Is the surgical stress associated with worse survival in patients with esophageal cancer?--Analysis of colon substitution for 37 patients with remnant stomach.
Hepato-gastroenterology 2007;54(75):791-5.
2007: Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Tooru Shiratori; Kiyohiko Shuto; Yasunori Akutsu; Yoshihiro Nabeya; Hideki Hayashi; Takenori Ochiai
Surgical outcome after the clearance of abdominal metastatic lymph nodes in 138 patients with thoracic esophageal carcinoma.
American journal of surgery 2007;193(4):448-52; discussion 453.
2007: Hideaki Shimada; Tooru Shiratori; Shinichi Okazumi; Hisahiro Matsubara; Kiyohiko Shuto; Yasunori Akutsu; Kazuo Narushima; Yoshihiro Nabeya; Hideki Hayashi; Takenori Ochiai
Surgical outcome of elderly patients 75 years of age and older with thoracic esophageal carcinoma.
World journal of surgery 2007;31(4):773-9.
2007: Hideaki Shimada; Tooru Shiratori; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Kiyohiko Shuto; Takanori Shimizu; Hideki Hayashi; Takenori Ochiai
Surgical outcome of patients with thoracic esophageal cancer positive for cervical lymph nodes.
Hepato-gastroenterology 2007;54(73):100-3.
2007: T Uno; K Isobe; H Kawakami; N Ueno; Hideaki Shimada; Hisahiro Matsubara; Shinichi Okazumi; Yoshihiro Nabeya; Tooru Shiratori; T Kawata; Takenori Ochiai; H Ito
Concurrent chemoradiation for patients with squamous cell carcinoma of the cervical esophagus.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2007;20(1):12-8.
2006: Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Tooru Shiratori; Kiyohiko Shuto; Takanori Shimizu; Yasunori Akutsu; Yutaka Tanizawa; Hideki Hayashi; Takenori Ochiai
Location and clinical impact of solitary lymph node metastasis in patients with thoracic esophageal carcinoma.
American journal of surgery 2006;192(3):306-10.
2006: Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Tooru Shiratori; Takanori Shimizu; Kiyohiko Shuto; Hideki Hayashi; Takenori Ochiai
Impact of the number and extent of positive lymph nodes in 200 patients with thoracic esophageal squamous cell carcinoma after three-field lymph node dissection.
World journal of surgery 2006;30(8):1441-9.
2006: Hideaki Shimada; Hisahiro Matsubara; Tooru Shiratori; Takanori Shimizu; Shinichi Miyazaki; Shinichi Okazumi; Yoshihiro Nabeya; Kiyohiko Shuto; Hideki Hayashi; Tooru Tanizawa; Yukio Nakatani; Hiromitsu Nakasa; Mitsukazu Kitada; Takenori Ochiai
Phase I/II adenoviral p53 gene therapy for chemoradiation resistant advanced esophageal squamous cell carcinoma.
Cancer science 2006;97(6):554-61.
2006: Kazuyuki Matsushita; Takeshi Tomonaga; Hideaki Shimada; Ayumi Shioya; Morihiro Higashi; Hisahiro Matsubara; Kenichi Harigaya; Fumio Nomura; Daniel Libutti; David Levens; Takenori Ochiai
An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis.
Cancer research 2006;66(3):1409-17.
2006: Hideaki Shimada; Yoshihiro Nabeya; Hisahiro Matsubara; Shinichi Okazumi; Tooru Shiratori; Takanori Shimizu; Taito Aoki; Kiyohiko Shuto; Yasunori Akutsu; Takenori Ochiai
Prediction of lymph node status in patients with superficial esophageal carcinoma: analysis of 160 surgically resected cancers.
American journal of surgery 2006;191(2):250-4.
2006: Takanori Nishimori; Takeshi Tomonaga; Kazuyuki Matsushita; Masamichi Oh-Ishi; Yoshio Kodera; Tadakazu Maeda; Fumio Nomura; Hisahiro Matsubara; Hideaki Shimada; Takenori Ochiai
Proteomic analysis of primary esophageal squamous cell carcinoma reveals downregulation of a cell adhesion protein, periplakin.
Proteomics 2006;6(3):1011-8.
2006: Yasunori Akutsu; Hisahiro Matsubara; Hideki Hayashi; Shinichi Okazumi; Taito Aoki; Teruo Kozu; Takenori Ochiai
Endoscope-assisted thoracoscopic technique for esophageal bronchogenic cyst which presented elevated CA125.
Digestive surgery 2006;23(4):209-14.
2006: Kazuyuki Matsushita; Takenori Ochiai; Hideaki Shimada; Shingo Kato; Tatsuya Ohno; Takashi Nikaido; Shigeru Yamada; Shinichi Okazumi; Hisahiro Matsubara; Wataru Takayama; Hiroshi Ishikura; Hiroshi Tsujii
The effects of carbon ion irradiation revealed by excised perforated intestines as a late morbidity for uterine cancer treatment.
Surgery today 2006;36(8):692-700.
2006: Kazuyuki Matsushita; Toshinao Takenouchi; Hideaki Shimada; Takeshi Tomonaga; Hideki Hayashi; Ayumi Shioya; Aki Komatsu; Hisahiro Matsubara; Takenori Ochiai
Strong HLA-DR antigen expression on cancer cells relates to better prognosis of colorectal cancer patients: Possible involvement of c-myc suppression by interferon-gamma in situ.
Cancer science 2006;97(1):57-63.
2006: Hiroyuki Yamada; Masaaki Ebara; Tadashi Yamaguchi; Shinichirou Okabe; Hiroyuki Fukuda; Masaharu Yoshikawa; Takashi Kishimoto; Hisahiro Matsubara; Hiroyuki Hachiya; Hiroshi Ishikura; Hiromitsu Saisho
A pilot approach for quantitative assessment of liver fibrosis using ultrasound: preliminary results in 79 cases.
Journal of hepatology 2006;44(1):68-75.
2005: Isamu Hoshino; Hisahiro Matsubara; Naoyuki Hanari; Mikito Mori; Takanori Nishimori; Yasuo Yoneyama; Yasunori Akutsu; Haruhito Sakata; Kazuyuki Matsushita; Naohiko Seki; Takenori Ochiai
Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7945-52.
2005: Taichi Kawashima; Yukimasa Miyazawa; Haruhito Sakata; Hisahiro Matsubara; Munemasa Ryu; Takenori Ochiai
[A case regarded as an occult breast cancer treated without mastectomy].
Gan to kagaku ryoho. Cancer & chemotherapy 2005;32(6):825-8.
2005: Yoshio Gunji; Takashi Nikaidou; Shinichi Okazumi; Hisahiro Matsubara; Hideaki Shimada; Yoshihiro Nabeya; Taito Aoki; Haruhumi Makino; Shinichi Miyazaki; Takenori Ochiai
Evaluation of Ki-67 and p53 expression in primary and repeated liver metastases of GISTs.
Hepato-gastroenterology 2005;52(63):829-32.
2005: Yoshio Gunji; Masaya Uesato; Shinichi Miyazaki; Hideaki Shimada; Hisahiro Matsubara; Yoshihiro Nabeya; Keiji Kouda; Harufumi Makino; Teruo Kouzu; Takenori Ochiai
Generation of antitumor immunity against large colon tumors by repeated runs of electrochemotherapy.
Hepato-gastroenterology 2005;52(63):770-4.
2005: Nobuo Hirayama; Yoshio Gunji; Shinichi Miyazaki; Takehito Kaiho; Hideaki Shimada; Hisahiro Matsubara; Yoshihiro Nabeya; Taito Aoki; Susumu Kobayashi; Takenori Ochiai
Inhibitory remnant stomach motility by duodenal distention after B-I gastrectomy.
Hepato-gastroenterology 2005;52(62):633-8.
2005: Yoshihiro Nabeya; Takenori Ochiai; Hisahiro Matsubara; Shinichi Okazumi; Tooru Shiratori; Kiyohiko Shuto; Taito Aoki; S Miyazaki; Yoshio Gunji; T Uno; H Ito; Hideaki Shimada
Neoadjuvant chemoradiotherapy followed by esophagectomy for initially resectable squamous cell carcinoma of the esophagus with multiple lymph node metastasis.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2005;18(6):388-97.
2005: Takayuki Tohma; Shinichi Okazumi; Harufumi Makino; Akihiro Cho; Ryoyu Mochizuki; Kiyohiko Shuto; Hidehiro Kudo; Katsuhiko Matsubara; Hisashi Gunji; Hisahiro Matsubara; Takenori Ochiai
Overexpression of glucose transporter 1 in esophageal squamous cell carcinomas: a marker for poor prognosis.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2005;18(3):185-9.
2004: Kazue Nakashima; Hideaki Shimada; Takenori Ochiai; Mari Kuboshima; Namiko Kuroiwa; Shinichi Okazumi; Hisahiro Matsubara; Fumio Nomura; Masaki Takiguchi; Takaki Hiwasa
Serological identification of TROP2 by recombinant cDNA expression cloning using sera of patients with esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2004;112(6):1029-35.
2004: Masaya Uesato; Yoshio Gunji; Takeshi Tomonaga; Shinichi Miyazaki; Tooru Shiratori; Hisahiro Matsubara; Teruo Kouzu; Hideaki Shimada; Fumio Nomura; Takenori Ochiai
Synergistic antitumor effect of antiangiogenic factor genes on colon 26 produced by low-voltage electroporation.
Cancer gene therapy 2004;11(9):625-32.
2004: Gaku Oohira; Shigeru Yamada; Takenori Ochiai; Hisahiro Matsubara; Shinichi Okazumi; Koichi Ando; Hirohiko Tsujii; Takaki Hiwasa; Hideaki Shimada
Growth suppression of esophageal squamous cell carcinoma induced by heavy carbon-ion beams combined with p53 gene transfer.
International journal of oncology 2004;25(3):563-9.
2004: Mikito Mori; Hideaki Shimada; Yoshio Gunji; Hisahiro Matsubara; Hideki Hayashi; Yoshinori Nimura; Masaki Kato; Masaki Takiguchi; Takenori Ochiai; Naohiko Seki
S100A11 gene identified by in-house cDNA microarray as an accurate predictor of lymph node metastases of gastric cancer.
Oncology reports 2004;11(6):1287-93.
2004: Takehito Kaiho; Yoshio Gunji; Nobuo Hirayama; Hideki Hayashi; Shinichi Miyazaki; Hideaki Shimada; Yoshihiro Nabeya; Hisahiro Matsubara; Susumu Kobayashi; Takenori Ochiai
Effect of the anastomosis-site after Billroth I gastrectomy on the motility of the remnant stomach.
Hepato-gastroenterology 2004;51(57):906-11.
2004: Hideaki Shimada; Gaku Oohira; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Hideki Hayashi; Akihiko Takeda; Yoshio Gunji; Takenori Ochiai
Thrombocytosis associated with poor prognosis in patients with esophageal carcinoma.
Journal of the American College of Surgeons 2004;198(5):737-41.
2004: Shinichi Okazumi; Takenori Ochiai; Hideaki Shimada; Hisahiro Matsubara; Yoshihiro Nabeya; Yukimasa Miyazawa; Tooru Shiratori; Taito Aoki; Makoto Sugaya
Development of less invasive surgical procedures for thoracic esophageal cancer.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2004;17(2):159-63.
2003: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Tooru Shiratori; Taito Aoki; Makoto Sugaya; Yukimasa Miyazawa; Hideki Hayashi; Shin-Ichi Miyazaki; Takenori Ochiai
Elevation of preoperative serum C-reactive protein level is related to poor prognosis in esophageal squamous cell carcinoma.
Journal of surgical oncology 2003;83(4):248-52.
2003: Hisahiro Matsubara; Takenori Ochiai
[Progress of gene therapy for esophageal cancer in Japan].
Gan to kagaku ryoho. Cancer & chemotherapy 2003;30(7):944-9.
2003: Yoshio Gunji; Takao Suzuki; Susumu Kobayashi; Seiji Hori; Hideki Hayashi; Hideaki Shimada; Hisahiro Matsubara; Yoshihiro Nabeya; Takenori Ochiai
Evaluation of D3/D4 lymph node dissection for patients with grossly N2 positive advanced gastric cancer.
Hepato-gastroenterology 2003;50(52):1178-82.
2003: Hideaki Shimada; Yoshihiro Nabeya; Masatoshi Tagawa; Shinichi Okazumi; Hisahiro Matsubara; Kenji Kadomatsu; Takashi Muramatsu; Shinya Ikematsu; Sadatoshi Sakuma; Takenori Ochiai
Preoperative serum midkine concentration is a prognostic marker for esophageal squamous cell carcinoma.
Cancer science 2003;94(7):628-32.
2003: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Tooru Shiratori; Yoshio Gunji; Susumu Kobayashi; Hideki Hayashi; Takenori Ochiai
Prediction of survival with squamous cell carcinoma antigen in patients with resectable esophageal squamous cell carcinoma.
Surgery 2003;133(5):486-94.
2003: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yukimasa Miyazawa; Tooru Shiratori; Hideki Hayashi; Yoshio Gunji; Takenori Ochiai
Prognostic significance of CYFRA 21-1 in patients with esophageal squamous cell carcinoma.
Journal of the American College of Surgeons 2003;196(4):573-8.
2003: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Kenji Kadomatsu; Takashi Muramatsu; Shinya Ikematsu; Sadatoshi Sakuma; Takenori Ochiai
Increased serum midkine concentration as a possible tumor marker in patients with superficial esophageal cancer.
Oncology reports 2003;10(2):411-4.
2003: Nobuo Hirayama; Miwako Arima; Shin-Ichi Miyazaki; Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Takao Suzuki; Takenori Ochiai; Teruo Kouzu
Endoscopic mucosal resection of adenocarcinoma arising in ectopic gastric mucosa in the cervical esophagus: case report.
Gastrointestinal endoscopy 2003;57(2):263-6.
2003: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yukimasa Miyazawa; T Shihratori; H Hayashi; Taito Aoki; Makoto Sugaya; Yoshio Gunji; S Kobayashi; Takenori Ochiai
Prognostic value of preoperative serum immunosuppressive acidic protein in patients with esophageal squamous cell carcinoma.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus / I.S.D.E 2003;16(2):102-6.
2003: Y Gunji; T Suzuki; S Hori; Hideki Hayashi; Hisahiro Matsubara; H Shimada; Takenori Ochiai
Prognostic significance of the number of metastatic lymph nodes in early gastric cancer.
Digestive surgery 2003;20(2):148-53.
2003: Hideaki Shimada; Hiroyuki Kitabayashi; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yutaka Funami; Yukimasa Miyazawa; Tooru Shiratori; Takashi Uno; Hisao Itoh; Takenori Ochiai
Treatment response and prognosis of patients after recurrence of esophageal cancer.
Surgery 2003;133(1):24-31.
2003: Shinichi Miyazaki; Yoshio Gunji; Hisahiro Matsubara; Hideaki Shimada; Masaya Uesato; Takao Suzuki; Teruo Kouzu; Takenori Ochiai
Possible involvement of antitumor immunity in the eradication of colon 26 induced by low-voltage electrochemotherapy with bleomycin.
Surgery today 2003;33(1):39-44.
2003: Hideki Hayashi; Takenori Ochiai; Mikito Mori; Tomoaki Karube; Takao Suzuki; Yoshio Gunji; Seiji Hori; Naotake Akutsu; Hisahiro Matsubara; Hideaki Shimada
Sentinel lymph node mapping for gastric cancer using a dual procedure with dye- and gamma probe-guided techniques.
Journal of the American College of Surgeons 2003;196(1):68-74.
2002: Hideaki Shimada; Hisahiro Matsubara; Takenori Ochiai
p53 gene therapy for esophageal cancer.
Journal of gastroenterology 2002;37 Suppl 14():87-91.
2002: Hideaki Shimada; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yutaka Funami; Tooru Shiratori; Hideki Hayashi; Akihiko Takeda; Takenori Ochiai
Prognostic significance of serum p53 antibody in patients with esophageal squamous cell carcinoma.
Surgery 2002;132(1):41-7.
2002: Hideaki Shimada; Hisahiro Matsubara; Takenori Ochiai
[Gene therapy for esophageal cancer].
Nihon Geka Gakkai zasshi 2002;103(4):371-5.
2002: Hideaki Shimada; Akihiko Takeda; Tooru Shiratori; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yutaka Funami; Hideki Hayashi; Yoshio Gunji; Susumu Kobayashi; Takao Suzuki; Takenori Ochiai
Prognostic significance of serum thymidine phosphorylase concentration in esophageal squamous cell carcinoma.
Cancer 2002;94(7):1947-54.
2002: Yoshihiro Nabeya; Hideaki Shimada; Shinichi Okazumi; Hisahiro Matsubara; Yoshio Gunji; Takao Suzuki; Takenori Ochiai
Serum cross-linked carboxyterminal telopeptide of type I collagen (ICTP) as a prognostic tumor marker in patients with esophageal squamous cell carcinoma.
Cancer 2002;94(4):940-9.
2002: Hideaki Shimada; T Hoshino; Shinichi Okazumi; Hisahiro Matsubara; Yutaka Funami; Yoshihiro Nabeya; Hideki Hayashi; Akihiko Takeda; Tooru Shiratori; Takashi Uno; Haruo Ito; Takenori Ochiai
Expression of angiogenic factors predicts response to chemoradiotherapy and prognosis of oesophageal squamous cell carcinoma.
British journal of cancer 2002;86(4):552-7.
2002: Yoshio Gunji; Serdar Yol; Takao Suzuki; Seiji Hori; Hideki Hayashi; Hideaki Shimada; Hisahiro Matsubara; Yoshihiro Nabeya; Takenori Ochiai
Analysis of experimental liver metastasis from tumors inoculated in the mouse stomach cavity.
Surgery today 2002;32(2):142-7.
2001: Hideaki Shimada; Akihiko Takeda; Yoshihiro Nabeya; Shinichi Okazumi; Hisahiro Matsubara; Yutaka Funami; Hideki Hayashi; Yoshio Gunji; Susumu Kobayashi; Takao Suzuki; Takenori Ochiai
Clinical significance of serum vascular endothelial growth factor in esophageal squamous cell carcinoma.
Cancer 2001;92(3):663-9.
2001: Hisahiro Matsubara; Yoshio Gunji; T Maeda; K Tasaki; Y Koide; Takehide Asano; Takenori Ochiai; Shigeru Sakiyama; Masatoshi Tagawa
Electroporation-mediated transfer of cytokine genes into human esophageal tumors produces anti-tumor effects in mice.
Anticancer research 2001;21(4A):2501-3.
2001: Hisahiro Matsubara; T Maeda; Yoshio Gunji; Y Koide; Takehide Asano; Takenori Ochiai; Shigeru Sakiyama; Masatoshi Tagawa
Combinatory anti-tumor effects of electroporation-mediated chemotherapy and wild-type p53 gene transfer to human esophageal cancer cells.
International journal of oncology 2001;18(4):825-9.
2001: Hideaki Shimada; Takanori Shimizu; Takenori Ochiai; Tian-Ling Liu; Hiroshi Sashiyama; A Nakamura; Hisahiro Matsubara; Yoshio Gunji; Susumu Kobayashi; Masatoshi Tagawa; S Sakiyama; Takaki Hiwasa
Preclinical study of adenoviral p53 gene therapy for esophageal cancer.
Surgery today 2001;31(7):597-604.
2001: Hideaki Shimada; Shinichi Okazumi; Akihiko Takeda; Yoshihiro Nabeya; Hisahiro Matsubara; Yutaka Funami; Hideki Hayashi; Yoshio Gunji; Takao Suzuki; Takenori Ochiai
Presence of serum p53 antibodies is associated with decreased in vitro chemosensitivity in patients with esophageal cancer.
Surgery today 2001;31(7):591-6.
2000: Hideaki Shimada; Takenori Ochiai; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Yukimasa Miyazawa; M Arima; Yutaka Funami; Hideki Hayashi; Akihiko Takeda; Yoshio Gunji; Takao Suzuki; Susumu Kobayashi
Clinical benefits of steroid therapy on surgical stress in patients with esophageal cancer.
Surgery 2000;128(5):791-8.
2000: Hideaki Shimada; Akihiko Takeda; M Arima; Shinichi Okazumi; Hisahiro Matsubara; Yoshihiro Nabeya; Yutaka Funami; Hideki Hayashi; Yoshio Gunji; Takao Suzuki; Susumu Kobayashi; Takenori Ochiai
Serum p53 antibody is a useful tumor marker in superficial esophageal squamous cell carcinoma.
Cancer 2000;89(8):1677-83.
2000: Hisahiro Matsubara; Takenori Ochiai
[The protocol of clinical trial and basic experiments for esophageal cancer using gene transduction].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(9):1935-43.
2000: Takao Suzuki; Takenori Ochiai; K Nakajima; Hisahiro Matsubara; M Arima; S Hori; Hideki Hayashi; Hideaki Shimada; Akihiko Takeda; T Yanagawa; K Sen
A feasibility study of chemosensitivity assay by adhesive tumor cell culture system using biopsy specimens for gastric cancer.
Journal of surgical oncology 2000;74(2):141-7.
2000: T Maeda; Hisahiro Matsubara; Y Koide; M Sugaya; Yukimasa Miyazawa; K Tasaki; Kaichi Isono; Takenori Ochiai; Shigeru Sakiyama; Masatoshi Tagawa
Radiosensitivity of human breast cancer cells transduced with wild-type p53 gene is influenced by the p53 status of parental cells.
Anticancer research 2000;20(2A):869-74.
2000: Yoshio Gunji; Takenori Ochiai; Hideaki Shimada; Hisahiro Matsubara
Gene therapy for cancer.
Surgery today 2000;30(11):967-73.
1999: T Maeda; Hisahiro Matsubara; M Sugaya; Y Miyazawa; Yoshio Gunji; Takenori Ochiai; Shigeru Sakiyama; Masatoshi Tagawa
Loss of tumorigenicity of human breast cancer cells engineered to produce IL-2, IL-4 or GM-CSF in nude mice.
International journal of oncology 1999;15(5):943-7.
1999: Hisahiro Matsubara; Kiyoko Kawamura; M Sugaya; Y Koide; Yoshio Gunji; Keizo Takenaga; Takehide Asano; Takenori Ochiai; Shigeru Sakiyama; Masatoshi Tagawa
Differential efficacy of suicide gene therapy by herpes simplex virus-thymidine kinase gene reflects the status of p53 gene in human esophageal cancer cells.
Anticancer research 1999;19(5B):4157-60.
1999: Hisahiro Matsubara; M Kimura; M Sugaya; Y Koide; Yoshio Gunji; K Takegana; Takehide Asano; Takenori Ochiai; K Isono; Shigeru Sakiyama; Masatoshi Tagawa
Expression of wild-type p53 gene confers increased sensitivity to radiation and chemotherapeutic agents in human esophageal carcinoma cells.
International journal of oncology 1999;14(6):1081-5.
1998: Hisahiro Matsubara; Y Koide; M Sugaya; Yoshio Gunji; Takehide Asano; Takenori Ochiai; K Takegana; Shigeru Sakiyama; Masatoshi Tagawa
Antitumor response of genetically engineered IL-2 expression to human esophageal carcinoma cells in mature T cell-defective condition.
International journal of oncology 1998;13(6):1217-22.
1998: Yoshio Gunji; K Tasaki; Masatoshi Tagawa; Hisahiro Matsubara; Keizo Takenaga; Takeo Suzuki; Takehide Asano; Takenori Ochiai; Kaichi Isono; Shigeru Sakiyama
Inhibition of peritoneal dissemination of murine colon carcinoma cells by administrating retrovirus harboring IL-2 gene.
Cancer gene therapy 1998;5(6):339-43.
1998: Hideaki Shimada; K Nakajima; Takenori Ochiai; Y Koide; Shinichi Okazumi; Hisahiro Matsubara; Akihiko Takeda; Y Miyazawa; M Arima; K Isono
Detection of serum p53 antibodies in patients with esophageal squamous cell carcinoma: correlation with clinicopathologic features and tumor markers.
Oncology reports 1998;5(4):871-4.
1998: K Tasaki; Yoshio Gunji; Hisahiro Matsubara; Keizo Takenaga; Takeo Suzuki; Takehide Asano; Takenori Ochiai; Kaichi Isono; Teruo Kouzu; Shigeru Sakiyama; Masatoshi Tagawa
Induction of T cell dependent acquired immunity in syngeneic mice by the combined expression of interleukin-4 and granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.
Anticancer research 1998;18(3A):1453-6.
1998: K Tasaki; Masatoshi Tagawa; Yoshio Gunji; Hisahiro Matsubara; Keizo Takenaga; M Muramatsu; S Fujimura; Takeo Suzuki; Takehide Asano; Takenori Ochiai; Kaichi Isono; Teruo Kouzu; Shigeru Sakiyama
Inhibition of experimental lung metastasis of murine colon carcinoma cells depends on the amount of interleukin-2 secreted from the transduced cells.
Anticancer research 1998;18(2A):813-7.
1998: M Sugaya; Masatoshi Tagawa; Hisahiro Matsubara; Yoshio Gunji; Keizo Takenaga; T Maeda; Y Koide; Takehide Asano; Takenori Ochiai; K Isono; Shigeru Sakiyama
Induction of antitumor effect on human esophageal carcinoma cells by the retroviral expression of granulocyte macrophage-colony stimulating factor gene.
International journal of oncology 1998;12(2):321-4.
1998: Hiroshi Sashiyama; H Matsubara; Y Koide; Hisahiro Matsubara; Takenori Ochiai; Kaichi Isono
Benign esophageal stricture caused by diffuse severe esophagitis presenting as ascending fibrosis: report of a case.
Surgery today 1998;28(5):538-41.
1997: Y Koide; Shinichi Okazumi; Hideaki Shimada; Hisahiro Matsubara; Y Miyazawa; Miwako Arima; A Komori; T Fukunaga; K Isono
[Reasonable lymph node dissection for T2 or T3 midthoracic esophageal cancer with cervical lymph-node metastasis].
Nihon Geka Gakkai zasshi 1997;98(9):742-6.
1997: T Urashima; K Saigo; S Kobayashi; Hitoshi Imaseki; Hisahiro Matsubara; Y Koide; Takehide Asano; Y Kondo; K Koike; Kaichi Isono
Identification of hepatitis B virus integration in hepatitis C virus-infected hepatocellular carcinoma tissues.
Journal of hepatology 1997;26(4):771-8.
1996: Yoshio Gunji; Masatoshi Tagawa; Hisahiro Matsubara; Keizo Takenaga; M Sugaya; K Tasaki; T Maeda; F Kondo; K Nakajima; Takeo Suzuki; Takehide Asano; Takenori Ochiai; K Isono; Shigeru Sakiyama
Inhibition of peritoneal dissemination of colon carcinoma in syngeneic mice immunized with interleukin-2-producing cells.
Cancer letters 1996;109(1-2):171-6.
1996: Yoshio Gunji; Masatoshi Tagawa; Hisahiro Matsubara; Keizo Takenaga; H Shimada; F Kondo; Takeo Suzuki; K Nakajima; M Sugaya; Takehide Asano; Takenori Ochiai; K Isono; K Horitsu; H Kageyama; Y Nakamura; Shigeru Sakiyama
Antitumor effect induced by the expression of granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.
Cancer letters 1996;101(2):257-61.
1996: Yoshio Gunji; Masatoshi Tagawa; Hisahiro Matsubara; K Takenaga; H Shimada; F Kondo; Takeo Suzuki; K Nakajima; T Aoki; Takehide Asano; Takenori Ochiai; K Isono; H Kageyama; Y Nakamura; Shigeru Sakiyama
Murine colon carcinoma cells engineered to produce human interleukin-2 induce tumor-specific anti-tumor response.
International journal of cancer. Journal international du cancer 1996;66(1):135-9.
1996: Hisahiro Matsubara; Masatoshi Tagawa; Yoshio Gunji; Keizo Takenaga; M Sugaya; T Urashima; Y Koide; Takeo Suzuki; Takehide Asano; Takenori Ochiai; K Isono; H Kageyama; Y Nakamura; Shigeru Sakiyama
Study of irradiation effects on cytokine secretion from retrovirally-transduced tumor cells: a model for tumor vaccination.
Anticancer research 1996;16(2):645-50.
1995: T Urashima; K Saigo; Susumu Kobayashi; Hisahiro Matsubara; Y Koide; Takehide Asano; K Isono; F Kondo; Y Kondo
[Integration of hepatitis B virus and its significance in hepatocarcinogenesis].
Nihon rinsho. Japanese journal of clinical medicine 1995;53 Suppl(Pt 2):735-9.