FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kunihiro Matsumoto

Research Profile

Chemicals & Drugs

Physiology

Living Beings

Mouse
Rats

Phenomena

Phosphorylation

Anatomy

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Amino Acid Sequences

Co-author Network

Publications

TOP 3
Akitoshi Inoue; Manabi Fujiwara; Naoki Hisamoto; Tomohiro Kitazono; Kunihiro Matsumoto; Etsuko Sawatari; Takayuki Teramoto; Takeshi Ishihara
Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway.
Ayuna Hattori; Naoki Hisamoto; Mayuko Akamatsu; Tomoaki Mizuno; Kunihiro Matsumoto
The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex.
Masaharu Uno; Tomohito Yamamoto; Takuya Yamamoto; Miki Ebisuya; Sakiko Honjoh; Haruka Hoshikawa; Saya Kishimoto; Mitsuhiro Matsuda; Kunihiro Matsumoto; Eisuke Nishida
A fasting-responsive signaling pathway that extends life span in C. elegans.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kunihiro Matsumoto (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Akitoshi Inoue; Manabi Fujiwara; Naoki Hisamoto; Tomohiro Kitazono; Kunihiro Matsumoto; Etsuko Sawatari; Takayuki Teramoto; Takeshi Ishihara
Forgetting in C. elegans is accelerated by neuronal communication via the TIR-1/JNK-1 pathway.
Cell reports 2013;3(3):808-19.
2013: Ayuna Hattori; Naoki Hisamoto; Mayuko Akamatsu; Tomoaki Mizuno; Kunihiro Matsumoto
The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex.
PLoS genetics 2013;9(2):e1003315.
2013: Masaharu Uno; Tomohito Yamamoto; Takuya Yamamoto; Miki Ebisuya; Sakiko Honjoh; Haruka Hoshikawa; Saya Kishimoto; Mitsuhiro Matsuda; Kunihiro Matsumoto; Eisuke Nishida
A fasting-responsive signaling pathway that extends life span in C. elegans.
Cell reports 2013;3(1):79-91.
2012: Sho Morioka; Maiko Inagaki; Yoshihiro Komatsu; Kunihiro Matsumoto; Yuji Mishina; Jun Ninomiya-Tsuji
TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration.
Blood 2012;120(18):3846-57.
2012: Satoshi Ota; Nobuyuki Shimizu; Shizuka Ishitani; Motoyuki Itoh; Kunihiro Matsumoto; Tohru Ishitani
NLK positively regulates Wnt/β-catenin signalling by phosphorylating LEF1 in neural progenitor cells.
The EMBO journal 2012;31(8):1904-15.
2012: Chun Li; Michael Bastiani; Naoki Hisamoto; Shuka Kanao; Tomoaki Mizuno; Paola Nix; Kunihiro Matsumoto
The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade.
Nature neuroscience 2012;15(4):551-7.
2012: Kouki Ishikawa; Kunihiro Matsumoto; Atsuki Nara; Hiroshi Hanafusa
EGFR-dependent phosphorylation of leucine-rich repeat kinase LRRK1 is important for proper endosomal trafficking of EGFR.
Molecular biology of the cell 2012;23(7):1294-306.
2012: Emily Omori; Maiko Inagaki; Kunihiro Matsumoto; Yuji Mishina; Jun Ninomiya-Tsuji
Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(9):3365-70.
2012: Strahil Iv Pastuhov; Michael Bastiani; Kota Fujiki; Shuka Kanao; Kunihiro Matsumoto; Paola Nix; Naoki Hisamoto
Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling.
Nature communications 2012;3():1136.
2011: Hiroshi Hanafusa; Kunihiro Matsumoto
[Regulation of intracellular trafficking of the EGF receptor by ROCO family kinase LRRK1].
Seikagaku. The Journal of Japanese Biochemical Society 2011;83(12):1127-31.
2011: Emily Omori; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
Non-canonical β-catenin degradation mediates reactive oxygen species-induced epidermal cell death.
Oncogene 2011;30(30):3336-44.
2011: Teruyuki Hayakawa; Kumiko Kato; Ryoichi Hayakawa; Naoki Hisamoto; Kunihiro Matsumoto; Kohsuke Takeda; Hidenori Ichijo
Regulation of anoxic death in Caenorhabditis elegans by mammalian apoptosis signal-regulating kinase (ASK) family proteins.
Genetics 2011;187(3):785-92.
2011: Makoto Arimoto; Sandhya P Koushika; Bikash C Choudhary; Chris Li; Kunihiro Matsumoto; Naoki Hisamoto
The Caenorhabditis elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(6):2216-24.
2011: Shizuka Ishitani; Kenji Inaba; Kunihiro Matsumoto; Tohru Ishitani
Homodimerization of Nemo-like kinase is essential for activation and nuclear localization.
Molecular biology of the cell 2011;22(2):266-77.
2011: Akira Nukazuka; Yoichi Oda; Hajime Fujisawa; Kunihiro Matsumoto; Shusaku Tamaki; Shin Takagi
A shift of the TOR adaptor from Rictor towards Raptor by semaphorin in C. elegans.
Nature communications 2011;2():484.
2010: Emily Omori; Kunihiro Matsumoto; Songyun Zhu; Robert C Smart; Jun Ninomiya-Tsuji
Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells.
Cancer research 2010;70(21):8417-25.
2010: Rie Kajino-Sakamoto; Emily Omori; Prashant K Nighot; Anthony T Blikslager; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(8):4729-37.
2010: Hiroshi Yagasaki; Yasuhiro Takahashi; Asahito Hama; Kazuko Kudo; Nobuhiro Nishio; Hisako Muramatsu; Masashi Tanaka; N Yoshida; Kunihiro Matsumoto; N Watanabe; Kanefusa Kato; Keizo Horibe; Seiji Kojima
Comparison of matched-sibling donor BMT and unrelated donor BMT in children and adolescent with acquired severe aplastic anemia.
Bone marrow transplantation 2010;45(10):1508-13.
2010: Tetsuya Okuyama; Hideki Inoue; Sadatsugu Ookuma; Takayuki Satoh; Kei Kano; Sakiko Honjoh; Naoki Hisamoto; Kunihiro Matsumoto; Eisuke Nishida
The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans.
The Journal of biological chemistry 2010;285(39):30274-81.
2010: M Yamamoto; Ryoko Morita; Takamasa Mizoguchi; Hiromi Matsuo; Miho Isoda; Tohru Ishitani; Ajay B Chitnis; Kunihiro Matsumoto; J Gage Crump; Katsuto Hozumi; Shigenobu Yonemura; Koichi Kawakami; Motoyuki Itoh
Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions.
Development (Cambridge, England) 2010;137(15):2527-37.
2010: Mitsuho Onimaru; Kenoki Ohuchida; T Egami; Kazuhiro Mizumoto; Eishi Nagai; L Cui; H Toma; Kunihiro Matsumoto; M Hashizume; Masao Tanaka
Gemcitabine synergistically enhances the effect of adenovirus gene therapy through activation of the CMV promoter in pancreatic cancer cells.
Cancer gene therapy 2010;17(8):541-9.
2010: Kazuya Sugiyama; Kenji Nishide; Hiromi Matsuo; Sayumi Okigawa; Makoto Okano; Tohru Ishitani; Kunihiro Matsumoto; Motoyuki Itoh
Delta1 family members are involved in filopodial actin formation and neuronal cell migration independent of Notch signaling.
Biochemical and biophysical research communications 2010;398(1):118-24.
2010: Tohru Ishitani; Tomoko Hirao; Maho Suzuki; Miho Isoda; Shizuka Ishitani; Kenichi Harigaya; Motoo Kitagawa; Kunihiro Matsumoto; Motoyuki Itoh
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex.
Nature cell biology 2010;12(3):278-85.
2010: Kota Fujiki; Tomoaki Mizuno; Naoki Hisamoto; Kunihiro Matsumoto
The Caenorhabditis elegans Ste20-related kinase and Rac-type small GTPase regulate the c-Jun N-terminal kinase signaling pathway mediating the stress response.
Molecular and cellular biology 2010;30(4):995-1003.
2010: Peter Broglie; Kunihiro Matsumoto; Shizuo Akira; David L Brautigan; Jun Ninomiya-Tsuji
Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway.
The Journal of biological chemistry 2010;285(4):2333-9.
2009: Tohru Ishitani; Shizuka Ishitani; Kunihiro Matsumoto; Motoyuki Itoh
Nemo-like kinase is involved in NGF-induced neurite outgrowth via phosphorylating MAP1B and paxillin.
Journal of neurochemistry 2009;111(5):1104-18.
2009: S Morioka; Emily Omori; T Kajino; R Kajino-Sakamoto; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP.
Oncogene 2009;28(23):2257-65.
2009: Hiroshi Hanafusa; Kunihiro Matsumoto; Eisuke Nishida
Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning.
Nature cell biology 2009;11(1):106-9.
2008: Tomoaki Mizuno; Kota Fujiki; Aya Sasakawa; Naoki Hisamoto; Kunihiro Matsumoto
Role of the Caenorhabditis elegans Shc adaptor protein in the c-Jun N-terminal kinase signaling pathway.
Molecular and cellular biology 2008;28(23):7041-9.
2008: Maiko Inagaki; Emily Omori; Jae-Young Kim; Yoshihiro Komatsu; Greg Scott; Manas K Ray; Gen Yamada; Kunihiro Matsumoto; Yuji Mishina; Jun Ninomiya-Tsuji
TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling.
The Journal of biological chemistry 2008;283(48):33080-6.
2008: Emily Omori; Sho Morioka; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity.
The Journal of biological chemistry 2008;283(38):26161-8.
2008: Rie Kajino-Sakamoto; Maiko Inagaki; Elisabeth Lippert; Shizuo Akira; Sylvie Robine; Kunihiro Matsumoto; Christian Jobin; Jun Ninomiya-Tsuji
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1143-52.
2008: Atsushi Kuhara; Masatoshi Okumura; Tsubasa Kimata; Yoshinori Tanizawa; Ryo Takano; Koutarou D Kimura; Hitoshi Inada; Kunihiro Matsumoto; Ikue Mori
Temperature sensing by an olfactory neuron in a circuit controlling behavior of C. elegans.
Science (New York, N.Y.) 2008;320(5877):803-7.
2008: Jae-Young Kim; Emily Omori; Kunihiro Matsumoto; Gabriel Núñez; Jun Ninomiya-Tsuji
TAK1 is a central mediator of NOD2 signaling in epidermal cells.
The Journal of biological chemistry 2008;283(1):137-44.
2008: Naoki Hisamoto; Tetsuo Moriguchi; Seiichi Urushiyama; Shohei Mitani; Hiroshi Shibuya; Kunihiro Matsumoto
Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity.
EMBO reports 2008;9(1):70-5.
2008: Kunihiro Matsumoto; Hiromasa Inoue; Miyuki Tsuda; Takako Nakano; Masashi Komori; Satoru Fukuyama; Yoichi Nakanishi
Different profiles of IL-10+IFN-gamma-IL-4-CD4+ T cells in the peripheral blood in atopic and non-atopic asthmatics.
Respiration; international review of thoracic diseases 2008;75(3):281-7.
2007: Wei-Chun HuangFu; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
Osmotic stress blocks NF-kappaB-dependent inflammatory responses by inhibiting ubiquitination of IkappaB.
FEBS letters 2007;581(29):5549-54.
2007: Aisa Sakaguchi-Nakashima; James Y Meir; Yishi Jin; Kunihiro Matsumoto; Naoki Hisamoto
LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins.
Current biology : CB 2007;17(7):592-8.
2007: Taisuke Kajino; Emily Omori; Shunsuke Ishii; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation.
The Journal of biological chemistry 2007;282(13):9475-81.
2006: Taisuke Kajino; Hong Ren; Shun-ichiro Iemura; Tohru Natsume; Bjarki Stefansson; David L Brautigan; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway.
The Journal of biological chemistry 2006;281(52):39891-6.
2006: Wei-Chun Huangfu; Emily Omori; Shizuo Akira; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways.
The Journal of biological chemistry 2006;281(39):28802-10.
2006: Junya Azuma; Yoshiaki Taniyama; Y Takeya; Kazuma Iekushi; Motokuni Aoki; N Dosaka; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara; Ryuichi Morishita
Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy.
Gene therapy 2006;13(16):1206-13.
2006: Emily Omori; Kunihiro Matsumoto; Hideki Sanjo; Shintaro Sato; Shizuo Akira; Robert C Smart; Jun Ninomiya-Tsuji
TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis.
The Journal of biological chemistry 2006;281(28):19610-7.
2006: Yasuhiro Ogura; Kazuhiro Mizumoto; Eishi Nagai; Mitsuhiko Murakami; Naoki Inadome; Michiyo Saimura; Kunihiro Matsumoto; Tetsuya Nakamura; Makoto Maemondo; Toshihiro Nukiwa; Masao Tanaka
Peritumoral injection of adenovirus vector expressing NK4 combined with gemcitabine treatment suppresses growth and metastasis of human pancreatic cancer cells implanted orthotopically in nude mice and prolongs survival.
Cancer gene therapy 2006;13(5):520-9.
2006: Hossein Hosseinkhani; Toshihiro Kushibiki; Kunihiro Matsumoto; Tetsuya Nakamura; Yasuhiko Tabata
Enhanced suppression of tumor growth using a combination of NK4 plasmid DNA-PEG engrafted cationized dextran complex and ultrasound irradiation.
Cancer gene therapy 2006;13(5):479-89.
2006: Hitoshi Inada; Hiroko Ito; John S Satterlee; Piali Sengupta; Kunihiro Matsumoto; Ikue Mori
Identification of guanylyl cyclases that function in thermosensory neurons of Caenorhabditis elegans.
Genetics 2006;172(4):2239-52.
2006: Noriyuki Uemura; Taisuke Kajino; Hideki Sanjo; Shintaro Sato; Shizuo Akira; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1 is a component of the Epstein-Barr virus LMP1 complex and is essential for activation of JNK but not of NF-kappaB.
The Journal of biological chemistry 2006;281(12):7863-72.
2006: Toshiro Matsui; I A Ogunwande; Kanthi J M Abesundara; Kunihiro Matsumoto
Anti-hyperglycemic Potential of Natural Products.
Mini reviews in medicinal chemistry 2006;6(3):349-56.
2005: Tetsuo Moriguchi; Seiichi Urushiyama; Naoki Hisamoto; Shun-ichiro Iemura; Shinichi Uchida; Tohru Natsume; Kunihiro Matsumoto; Hiroshi Shibuya
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
The Journal of biological chemistry 2005;280(52):42685-93.
2005: Jae Hyung An; Kelly Vranas; Michael Lucke; Hideki Inoue; Naoki Hisamoto; Kunihiro Matsumoto; T Keith Blackwell
Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16275-80.
2005: Tohru Ishitani; Kunihiro Matsumoto; Ajay B Chitnis; Motoyuki Itoh
Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability.
Nature cell biology 2005;7(11):1106-12.
2005: Shintaro Sato; Hideki Sanjo; Kiyoshi Takeda; Jun Ninomiya-Tsuji; Masahiro Yamamoto; Taro Kawai; Kunihiro Matsumoto; Osamu Takeuchi; Shizuo Akira
Essential function for the kinase TAK1 in innate and adaptive immune responses.
Nature immunology 2005;6(11):1087-95.
2005: Hideki Inoue; Naoki Hisamoto; Jae Hyung An; Riva P Oliveira; Eisuke Nishida; T Keith Blackwell; Kunihiro Matsumoto
The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response.
Genes & development 2005;19(19):2278-83.
2005: Satoshi Kishida; Hideki Sanjo; Shizuo Akira; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway.
Genes to cells : devoted to molecular & cellular mechanisms 2005;10(5):447-54.
2005: Rie Sakamoto; Dana T Byrd; Heather M Brown; Naoki Hisamoto; Kunihiro Matsumoto; Yishi Jin
The Caenorhabditis elegans UNC-14 RUN domain protein binds to the kinesin-1 and UNC-16 complex and regulates synaptic vesicle localization.
Molecular biology of the cell 2005;16(2):483-96.
2004: Toshihiro Kushibiki; Kunihiro Matsumoto; Tetsuya Nakamura; Yasuhiko Tabata
Suppression of tumor metastasis by NK4 plasmid DNA released from cationized gelatin.
Gene therapy 2004;11(15):1205-14.
2004: Koutarou D Kimura; Atsushi Miyawaki; Kunihiro Matsumoto; Ikue Mori
The C. elegans thermosensory neuron AFD responds to warming.
Current biology : CB 2004;14(14):1291-5.
2004: Dennis H Kim; Nicole T Liberati; Tomoaki Mizuno; Hideki Inoue; Naoki Hisamoto; Kunihiro Matsumoto; Frederick M Ausubel
Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(30):10990-4.
2004: Ayako Sakaguchi; Kunihiro Matsumoto; Naoki Hisamoto
Roles of MAP kinase cascades in Caenorhabditis elegans.
Journal of biochemistry 2004;136(1):7-11.
2004: Tomoaki Mizuno; Naoki Hisamoto; Takashi Terada; Tae Kondo; Makoto Adachi; Eisuke Nishida; Dennis H Kim; Frederick M Ausubel; Kunihiro Matsumoto
The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response.
The EMBO journal 2004;23(11):2226-34.
2004: Hiroshi Hanafusa; Satoru Torii; Takayuki Yasunaga; Kunihiro Matsumoto; Eisuke Nishida
Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty.
The Journal of biological chemistry 2004;279(22):22992-5.
2004: Tomofumi Tadauchi; Toshifumi Inada; Kunihiro Matsumoto; Kenji Irie
Posttranscriptional regulation of HO expression by the Mkt1-Pbp1 complex.
Molecular and cellular biology 2004;24(9):3670-81.
2004: Chie Kanei-Ishii; Jun Ninomiya-Tsuji; Jun Tanikawa; Teruaki Nomura; Tohru Ishitani; Satoshi Kishida; Kenji Kokura; Toshihiro Kurahashi; Emi Ichikawa-Iwata; Yongsok Kim; Kunihiro Matsumoto; Shunsuke Ishii
Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK.
Genes & development 2004;18(7):816-29.
2004: Takahiro Naiki; Tatsushi Wakayama; Daisuke Nakada; Kunihiro Matsumoto; Katsunori Sugimoto
Association of Rad9 with double-strand breaks through a Mec1-dependent mechanism.
Molecular and cellular biology 2004;24(8):3277-85.
2004: Bisei Ohkawara; Kyoko Shirakabe; Junko Hyodo-Miura; Ritsuko Matsuo; Naoto Ueno; Kunihiro Matsumoto; Hiroshi Shibuya
Role of the TAK1-NLK-STAT3 pathway in TGF-beta-mediated mesoderm induction.
Genes & development 2004;18(4):381-6.
2003: Tohru Ishitani; Giichi Takaesu; Jun Ninomiya-Tsuji; Hiroshi Shibuya; Richard B Gaynor; Kunihiro Matsumoto
Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling.
The EMBO journal 2003;22(23):6277-88.
2003: Daisuke Nakada; Kunihiro Matsumoto; Katsunori Sugimoto
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism.
Genes & development 2003;17(16):1957-62.
2003: Jun Ninomiya-Tsuji; Taisuke Kajino; Koichiro Ono; Toshihiko Ohtomo; Masahiko Matsumoto; Masashi Shiina; Masahiko Mihara; Masayuki Tsuchiya; Kunihiro Matsumoto
A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase.
The Journal of biological chemistry 2003;278(20):18485-90.
2003: Daisuke Nakada; Toshiyasu Shimomura; Kunihiro Matsumoto; Katsunori Sugimoto
The ATM-related Tel1 protein of Saccharomyces cerevisiae controls a checkpoint response following phleomycin treatment.
Nucleic acids research 2003;31(6):1715-24.
2003: Tohru Ishitani; Jun Ninomiya-Tsuji; Kunihiro Matsumoto
Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.
Molecular and cellular biology 2003;23(4):1379-89.
2003: Hideki Sanjo; Kiyoshi Takeda; Tohru Tsujimura; Jun Ninomiya-Tsuji; Kunihiro Matsumoto; Shizuo Akira
TAB2 is essential for prevention of apoptosis in fetal liver but not for interleukin-1 signaling.
Molecular and cellular biology 2003;23(4):1231-8.
2003: M Nakabayashi; Ryuichi Morishita; Hironori Nakagami; K Kuba; Kunihiro Matsumoto; Tadashi Nakamura; Yasuo Tano; Yasufumi Kaneda
HGF/NK4 inhibited VEGF-induced angiogenesis in in vitro cultured endothelial cells and in vivo rabbit model.
Diabetologia 2003;46(1):115-23.
2003: Tohru Ishitani; Satoshi Kishida; Junko Hyodo-Miura; Naoto Ueno; Jun Yasuda; Marian Waterman; Hiroshi Shibuya; Randall T Moon; Jun Ninomiya-Tsuji; Kunihiro Matsumoto
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling.
Molecular and cellular biology 2003;23(1):131-9.
2002: Kunihiro Matsumoto; Ryuichi Morishita; N Tomita; A Moriguchi; Keita Yamasaki; Motokuni Aoki; K Matsumoto; Tadashi Nakamura; J Higaki; Toshio Ogihara
Impaired endothelial dysfunction in diabetes mellitus rats was restored by oral administration of prostaglandin I2 analogue.
The Journal of endocrinology 2002;175(1):217-23.
2002: Dennis H Kim; Rhonda Feinbaum; Geneviève Alloing; Fred E Emerson; Danielle A Garsin; Hideki Inoue; Miho Tanaka-Hino; Naoki Hisamoto; Kunihiro Matsumoto; Man-Wah Tan; Frederick M Ausubel
A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity.
Science (New York, N.Y.) 2002;297(5581):623-6.
2002: Toshinari Toba; Tetsuya Nakamura; A K Lynn; Kunihiro Matsumoto; Seijun Fukuda; Makoto Yoshitani; Yoshio Hori; Yasuhiko Shimizu
Evaluation of peripheral nerve regeneration across an 80-mm gap using a polyglycolic acid (PGA)--collagen nerve conduit filled with laminin-soaked collagen sponge in dogs.
The International journal of artificial organs 2002;25(3):230-7.
2002: Yoshiaki Taniyama; K Tachibana; Kazuya Hiraoka; Motokuni Aoki; Seiji Yamamoto; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara; Yasufumi Kaneda; Ryuichi Morishita
Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle.
Gene therapy 2002;9(6):372-80.
2002: Kenji Irie; Tomofumi Tadauchi; Peter A Takizawa; Ronald D Vale; Kunihiro Matsumoto; Ira Herskowitz
The Khd1 protein, which has three KH RNA-binding motifs, is required for proper localization of ASH1 mRNA in yeast.
The EMBO journal 2002;21(5):1158-67.
2002: Miho Tanaka-Hino; Alvaro Sagasti; Naoki Hisamoto; Masato Kawasaki; Shunji Nakano; Jun Ninomiya-Tsuji; Cornelia I Bargmann; Kunihiro Matsumoto
SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans.
EMBO reports 2002;3(1):56-62.
2001: Kunihiro Matsumoto; Kiyoshi Tomioka
An approach to a chiral cycloalkanone-mediated asymmetric epoxidation of stilbene with oxone.
Chemical & pharmaceutical bulletin 2001;49(12):1653-7.
2001: Hidenobu Miura; Kazuo Nishimura; Akira Tsujimura; Kiyomi Matsumiya; Kunihiro Matsumoto; Tadashi Nakamura; Akihiko Okuyama
Effects of hepatocyte growth factor on E-cadherin-mediated cell-cell adhesion in DU145 prostate cancer cells.
Urology 2001;58(6):1064-9.
2001: Kunihiro Matsumoto; N Takayama; Junji Ohnishi; Eriko Ohnishi; Y Shirayoshi; Norio Nakatsuji; Hiroyoshi Ariga
Tumour invasion and metastasis are promoted in mice deficient in tenascin-X.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(12):1101-11.
2001: S Kawaguchi; Tetsuya Nakamura; Yasuhiko Shimizu; T Masuda; T Takigawa; Yu Liu; Hiroki Ueda; Takashi Sekine; Kunihiro Matsumoto
Mechanical properties of artificial tracheas composed of a mesh cylinder and a spiral stent.
Biomaterials 2001;22(23):3085-90.
2001: Yoshiaki Taniyama; Ryuichi Morishita; Kazuya Hiraoka; Motokuni Aoki; Hironori Nakagami; Keita Yamasaki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat diabetic hind limb ischemia model: molecular mechanisms of delayed angiogenesis in diabetes.
Circulation 2001;104(19):2344-50.
2001: Kunihiro Matsumoto; Tetsuya Nakamura; Seijun Fukuda; Takashi Sekine; Hiroki Ueda; Yasuhiko Shimizu
A gelatin coated collagen-polyglycolic acid composite membrane as a dural substitute.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2001;47(6):641-5.
2001: Tomoki Ikuta; Hiroyoshi Ariga; Kunihiro Matsumoto
Effect of tenascin-X together with vascular endothelial growth factor A on cell proliferation in cultured embryonic hearts.
Biological & pharmaceutical bulletin 2001;24(11):1320-3.
2001: Takao Kondo; Tatsushi Wakayama; Takahiro Naiki; Kunihiro Matsumoto; Kenji Sugimoto
Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms.
Science (New York, N.Y.) 2001;294(5543):867-70.
2001: Daisaku Tomioka; N Maehara; K Kuba; K Mizumoto; Masaki Tanaka; Kunihiro Matsumoto; Tadashi Nakamura
Inhibition of growth, invasion, and metastasis of human pancreatic carcinoma cells by NK4 in an orthotopic mouse model.
Cancer research 2001;61(20):7518-24.
2001: H Inoue; M Tateno; K Fujimura-Kamada; Giichi Takaesu; T Adachi-Yamada; Jun Ninomiya-Tsuji; Kenji Irie; Yasuyoshi Nishida; Kunihiro Matsumoto
A Drosophila MAPKKK, D-MEKK1, mediates stress responses through activation of p38 MAPK.
The EMBO journal 2001;20(19):5421-30.
2001: Tadahisa Shono; Takanori Inamura; Takato Morioka; Kunihiro Matsumoto; Shigeharu Suzuki; Kiyonobu Ikezaki; Toru Iwaki; Masashi Fukui
Vascular endothelial growth factor in chronic subdural haematomas.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(5):411-5.
2001: T Yamamoto; Kunihiro Matsumoto; Hirohisa Kurachi; Y Okamoto; Yukihiro Nishio; M Sakata; Keiichi Tasaka; Yuji Murata
Progesterone inhibits transcriptional activation of human chorionic gonadotropin-alpha gene through protein kinase A pathway in trophoblast cells.
Molecular and cellular endocrinology 2001;182(2):215-24.
2001: Takahiro Naiki; Takao Kondo; Daisuke Nakada; Kunihiro Matsumoto; Kenji Sugimoto
Chl12 (Ctf18) forms a novel replication factor C-related complex and functions redundantly with Rad24 in the DNA replication checkpoint pathway.
Molecular and cellular biology 2001;21(17):5838-45.
2001: Motokuni Aoki; Ryuichi Morishita; Seiji Hayashi; Nobuo Jo; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.
Diabetologia 2001;44(8):1034-42.
2001: Tetsuya Nakamura; Hiroki Ueda; Touru Tsuda; Y H Li; Tetsuya Kiyotani; M Inoue; Kunihiro Matsumoto; Takashi Sekine; L Yu; Suong-Hyu Hyon; Yasuhiko Shimizu
Long-term implantation test and tumorigenicity of polyvinyl alcohol hydrogel plates.
Journal of biomedical materials research 2001;56(2):289-96.
2001: Kunihiro Matsumoto; Hideo Taniura; Taichi Uetsuki; Kunihiko Yoshikawa
Necdin acts as a transcriptional repressor that interacts with multiple guanosine clusters.
Gene 2001;272(1-2):173-9.
2001: H Ueda; Tadashi Nakamura; Kunihiro Matsumoto; Yoshiki Sawa; Hikaru Matsuda; T Nakamura
A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats.
Cardiovascular research 2001;51(1):41-50.
2001: Koichiro Ono; Toshihiko Ohtomo; S Sato; Y Sugamata; M Suzuki; Naoki Hisamoto; Jun Ninomiya-Tsuji; Masayuki Tsuchiya; Kunihiro Matsumoto
An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK.
The Journal of biological chemistry 2001;276(26):24396-400.
2001: Tomoyuki Sumi; Kunihiro Matsumoto; Atsuhito Shibuya; Tadashi Nakamura
Activation of LIM kinases by myotonic dystrophy kinase-related Cdc42-binding kinase alpha.
The Journal of biological chemistry 2001;276(25):23092-6.
2001: Hirokazu Kashiwagi; Yoshiaki Tomiyama; S Nozaki; Teruo Kiyoi; Seiji Tadokoro; Kunihiro Matsumoto; Shigenori Honda; Satoru Kosugi; Yoshiyuki Kurata; Yuji Matsuzawa
Analyses of genetic abnormalities in type I CD36 deficiency in Japan: identification and cell biological characterization of two novel mutations that cause CD36 deficiency in man.
Human genetics 2001;108(6):459-66.
2001: N Suzuki; Matthew Buechner; K Nishiwaki; David H Hall; H Nakanishi; Y Takai; Naoki Hisamoto; Kunihiro Matsumoto
A putative GDP-GTP exchange factor is required for development of the excretory cell in Caenorhabditis elegans.
EMBO reports 2001;2(6):530-5.
2001: Kunihiro Matsumoto; Tadashi Nakamura
Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases.
Kidney international 2001;59(6):2023-38.
2001: H Azuma; Shiro Takahara; Kunihiro Matsumoto; Naotsugu Ichimaru; J D Wang; Toshiki Moriyama; Ana Maria Waaga; M Kitamura; Y Otsuki; Akihiko Okuyama; Y Katsuoka; Anil Chandraker; Mohamed H Sayegh; Tadashi Nakamura
Hepatocyte growth factor prevents the development of chronic allograft nephropathy in rats.
Journal of the American Society of Nephrology : JASN 2001;12(6):1280-92.
2001: Kiichiro Beppu; Akihiko Uchiyama; Takashi Morisaki; Kunihiro Matsumoto; Tetsuya Nakamura; Masao Tanaka; Mitsuo Katano
Hepatocyte growth factor production by peripheral blood mononuclear cells of recurrent cancer patients.
Anticancer research 2001;21(3C):2195-200.
2001: Yoshio Hori; Tetsuya Nakamura; Kunihiro Matsumoto; Yoshimochi Kurokawa; Susumu Satomi; Yasuhiko Shimizu
Experimental study on in situ tissue engineering of the stomach by an acellular collagen sponge scaffold graft.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2001;47(3):206-10.
2001: Kazuhiro Yamamoto; Ryuichi Morishita; Seiji Hayashi; H Matsushita; Hironori Nakagami; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells.
Hypertension 2001;37(5):1341-8.
2001: Mohamed Janabi; Shizuya Yamashita; Kenichi Hirano; Kunihiro Matsumoto; Norio Sakai; Hisatoyo Hiraoka; Hirokazu Kashiwagi; Yoshiaki Tomiyama; S Nozaki; Yuji Matsuzawa
Reduced adhesion of monocyte-derived macrophages from CD36-deficient patients to type I collagen.
Biochemical and biophysical research communications 2001;283(1):26-30.
2001: Alvaro Sagasti; Naoki Hisamoto; J Hyodo; Miho Tanaka-Hino; Kunihiro Matsumoto; Cornelia I Bargmann
The CaMKII UNC-43 activates the MAPKKK NSY-1 to execute a lateral signaling decision required for asymmetric olfactory neuron fates.
Cell 2001;105(2):221-32.
2001: Toshiro Matsui; T Ueda; Tomoyuki Oki; Koichi Sugita; Norihiko Terahara; Kunihiro Matsumoto
alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins.
Journal of agricultural and food chemistry 2001;49(4):1952-6.
2001: Toshiro Matsui; T Ueda; Tomoyuki Oki; Koichi Sugita; Norihiko Terahara; Kunihiro Matsumoto
alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 1. Survey of natural pigments with potent inhibitory activity.
Journal of agricultural and food chemistry 2001;49(4):1948-51.
2001: Shinya Mizuno; Kunihiro Matsumoto; Tadashi Nakamura
Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy.
Kidney international 2001;59(4):1304-14.
2001: Giichi Takaesu; Jun Ninomiya-Tsuji; Satoshi Kishida; X Li; G R Stark; Kunihiro Matsumoto
Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway.
Molecular and cellular biology 2001;21(7):2475-84.
2001: N Maehara; Kunihiro Matsumoto; K Kuba; K Mizumoto; Masaki Tanaka; Tadashi Nakamura
NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells.
British journal of cancer 2001;84(6):864-73.
2001: Tadashi Nakamura; S Aoki; K Kitajima; T Takahashi; Kunihiro Matsumoto; T Nakamura
Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein.
Biochimica et biophysica acta 2001;1518(1-2):63-72.
2001: Shunji Nishio; K Samoto; I Takeshita; Kunihiro Matsumoto; Toshio Matsushima; Masashi Fukui
Inverting papilloma of the sphenoid sinus: report of two cases.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2001;8(2):168-70.
2001: Masashi Komori; Hiroyasu Inoue; Kunihiro Matsumoto; Hiroshi Koto; Satoru Fukuyama; Hisamichi Aizawa; Nobuyuki Hara
PAF mediates cigarette smoke-induced goblet cell metaplasia in guinea pig airways.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L436-41.
2001: Yoshiaki Taniyama; Ryuichi Morishita; Motokuni Aoki; Hironori Nakagami; Kazuhiro Yamamoto; K Yamazaki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease.
Gene therapy 2001;8(3):181-9.
2001: Hironori Nakagami; Ryuichi Morishita; Kazuhiro Yamamoto; Yoshiaki Taniyama; Motokuni Aoki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; M Horiuchi; Toshio Ogihara
Mitogenic and antiapoptotic actions of hepatocyte growth factor through ERK, STAT3, and AKT in endothelial cells.
Hypertension 2001;37(2 Pt 2):581-6.
2001: Kunihiro Matsumoto; Ryuichi Morishita; Atsushi Moriguchi; Naruya Tomita; Motokuni Aoki; H Sakonjo; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Inhibition of neointima by angiotensin-converting enzyme inhibitor in porcine coronary artery balloon-injury model.
Hypertension 2001;37(2):270-4.
2001: Tomofumi Tadauchi; Kunihiro Matsumoto; Ira Herskowitz; Kenji Irie
Post-transcriptional regulation through the HO 3'-UTR by Mpt5, a yeast homolog of Pumilio and FBF.
The EMBO journal 2001;20(3):552-61.
2001: Tatsushi Wakayama; Takao Kondo; Satoshi Ando; Kunihiro Matsumoto; Kenji Sugimoto
Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae.
Molecular and cellular biology 2001;21(3):755-64.
2001: Takashi Sekine; Tetsuya Nakamura; Yasuhiko Shimizu; Hiroki Ueda; Kunihiro Matsumoto; Yukinobu Takimoto; Tetsuya Kiyotani
A new type of surgical adhesive made from porcine collagen and polyglutamic acid.
Journal of biomedical materials research 2001;54(2):305-10.
2001: Tomoyuki Sumi; Kunihiro Matsumoto; Tadashi Nakamura
Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase.
The Journal of biological chemistry 2001;276(1):670-6.
2001: Shinji Kunishima; Tadashi Matsushita; Tetsuhito Kojima; N Amemiya; Y M Choi; N Hosaka; M Inoue; Y Jung; S Mamiya; Kunihiro Matsumoto; Y Miyajima; G Zhang; C Ruan; K Saito; K S Song; H J Yoon; T Kamiya; Hidehiko Saito
Identification of six novel MYH9 mutations and genotype-phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions.
Journal of human genetics 2001;46(12):722-9.
2001: Toshinari Toba; Tetsuya Nakamura; Yasuhiko Shimizu; Kunihiro Matsumoto; Katsunori Ohnishi; Seijun Fukuda; Makoto Yoshitani; Hiroki Ueda; Yoshio Hori; Katsuaki Endo
Regeneration of canine peroneal nerve with the use of a polyglycolic acid-collagen tube filled with laminin-soaked collagen sponge: a comparative study of collagen sponge and collagen fibers as filling materials for nerve conduits.
Journal of biomedical materials research 2001;58(6):622-30.
2001: Keizo Horibe; M Fukuda; Y Miyajima; Kunihiro Matsumoto; M Kondo; J Inaba; Y Miyashita
Outcome prediction by molecular detection of minimal residual disease in bone marrow for advanced neuroblastoma.
Medical and pediatric oncology 2001;36(1):203-4.
2001: Hisamichi Aizawa; Shohei Takata; M Shigyo; Kunihiro Matsumoto; Hiroyasu Inoue; Nobuyuki Hara
N-omega-nitro-L-arginine methyl ester increases airway responsiveness to serotonin but not to acetylcholine in cats in vivo.
Respiration; international review of thoracic diseases 2001;68(3):286-91.
2001: Yoshio Hori; Tetsuya Nakamura; Kunihiro Matsumoto; Yoshimochi Kurokawa; Susumu Satomi; Yasuhiko Shimizu
Tissue engineering of the small intestine by acellular collagen sponge scaffold grafting.
The International journal of artificial organs 2001;24(1):50-4.
2000: K Kuba; Kunihiro Matsumoto; K Ohnishi; T Shiratsuchi; Masaki Tanaka; Tadashi Nakamura
Kringle 1-4 of hepatocyte growth factor inhibits proliferation and migration of human microvascular endothelial cells.
Biochemical and biophysical research communications 2000;279(3):846-52.
2000: Tadashi Nakamura; Shinya Mizuno; Kunihiro Matsumoto; Yoshiki Sawa; Hikaru Matsuda; T Nakamura
Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF.
The Journal of clinical investigation 2000;106(12):1511-9.
2000: K Kuba; Kunihiro Matsumoto; K Date; H Shimura; Masaki Tanaka; Tadashi Nakamura
HGF/NK4, a four-kringle antagonist of hepatocyte growth factor, is an angiogenesis inhibitor that suppresses tumor growth and metastasis in mice.
Cancer research 2000;60(23):6737-43.
2000: Tomoki Ikuta; Hiroyoshi Ariga; Kunihiro Matsumoto
Extracellular matrix tenascin-X in combination with vascular endothelial growth factor B enhances endothelial cell proliferation.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(11):913-927.
2000: K Hayashi; Shun Nakamura; Ryuichi Morishita; Atsushi Moriguchi; Motokuni Aoki; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Naohiko Sakai; Toshio Ogihara
In vivo transfer of human hepatocyte growth factor gene accelerates re-endothelialization and inhibits neointimal formation after balloon injury in rat model.
Gene therapy 2000;7(19):1664-71.
2000: M Kitamura; Kiyomi Matsumiya; Kazuo Nishimura; M Yamanaka; Kunihiro Matsumoto; Akihiko Okuyama
Effect of hepatocyte growth factor on sperm motility.
American journal of reproductive immunology (New York, N.Y. : 1989) 2000;44(4):193-6.
2000: Hironori Nakagami; Ryuichi Morishita; Kazuhiro Yamamoto; Yoshiaki Taniyama; Motokuni Aoki; S Kim; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Anti-apoptotic action of hepatocyte growth factor through mitogen-activated protein kinase on human aortic endothelial cells.
Journal of hypertension 2000;18(10):1411-20.
2000: Hiroya Ishikawa; Mitsuya Shimoda; A Yonekura; K Mishima; Kunihiro Matsumoto; Yutaka Osajima
Irreversible unfolding of myoglobin in an aqueous solution by supercritical carbon dioxide.
Journal of agricultural and food chemistry 2000;48(10):4535-9.
2000: Hitoo Nakano; Hisamichi Aizawa; Kunihiro Matsumoto; Satoru Fukuyama; Hiroyasu Inoue; Nobuyuki Hara
Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs.
European journal of pharmacology 2000;403(3):267-75.
2000: Yu Liu; Tetsuya Nakamura; Yasumich Yamamoto; Kunihiro Matsumoto; Takashi Sekine; Hiroki Ueda; Yasuhiko Shimizu
A new tracheal bioartificial organ: evaluation of a tracheal allograft with minimal antigenicity after treatment by detergent.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000;46(5):536-9.
2000: Y H Hwang; Toshiro Matsui; T Hanada; Mitsuya Shimoda; Kunihiro Matsumoto; Yutaka Osajima
Desorption behavior of sorbed flavor compounds from packaging films with ethanol solution.
Journal of agricultural and food chemistry 2000;48(9):4310-3.
2000: Tomoyuki Oki; Toshiro Matsui; Kunihiro Matsumoto
Evaluation of alpha-glucosidase inhibition by using an immobilized assay system.
Biological & pharmaceutical bulletin 2000;23(9):1084-7.
2000: Kunihiro Matsumoto; Hisamichi Aizawa; Hiroyasu Inoue; Hiroshi Koto; Satoru Fukuyama; Nobuyuki Hara
Effect of dimethylthiourea, a hydroxyl radical scavenger, on cigarette smoke-induced bronchoconstriction in guinea pigs.
European journal of pharmacology 2000;403(1-2):157-61.
2000: Mohamed Janabi; Shizuya Yamashita; Kenichi Hirano; Norio Sakai; Hisatoyo Hiraoka; Kunihiro Matsumoto; Zhongyan Zhang; S Nozaki; Yuji Matsuzawa
Oxidized LDL-induced NF-kappa B activation and subsequent expression of proinflammatory genes are defective in monocyte-derived macrophages from CD36-deficient patients.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(8):1953-60.
2000: Tomohiro Yamada; Michiyoshi Hisanaga; Yoshiyuki Nakajima; Shinya Mizuno; Kunihiro Matsumoto; Tadashi Nakamura; H Nakano
Enhanced expression of hepatocyte growth factor by pulmonary ischemia-reperfusion injury in the rat.
American journal of respiratory and critical care medicine 2000;162(2 Pt 1):707-15.
2000: Takahiro Naiki; Toshiyasu Shimomura; Takao Kondo; Kunihiro Matsumoto; Kenji Sugimoto
Rfc5, in cooperation with rad24, controls DNA damage checkpoints throughout the cell cycle in Saccharomyces cerevisiae.
Molecular and cellular biology 2000;20(16):5888-96.
2000: Yukako Atsumi; Takumi Imai; Kunihiro Matsumoto; Masayoshi Sakuda; Kojiro Kurisu; Satoshi Wakisaka
Effects of neonatal injury of the inferior alveolar nerve on the development and regeneration of periodontal nerve fibers in the rat incisor.
Brain research 2000;871(2):201-9.
2000: Yoshiaki Taniyama; Ryuichi Morishita; Hironori Nakagami; Atsushi Moriguchi; H Sakonjo; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters.
Circulation 2000;102(2):246-52.
2000: Kunihiro Matsumoto; Shinya Mizuno; Tadashi Nakamura
Hepatocyte growth factor in renal regeneration, renal disease and potential therapeutics.
Current opinion in nephrology and hypertension 2000;9(4):395-402.
2000: Takashi Sekine; Tetsuya Nakamura; Yu Liu; Hiroki Ueda; Kunihiro Matsumoto; Yasuhiko Shimizu
Collagen coated Y-shaped prosthesis for carinal replacement promotes regeneration of the tracheal epithelium.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000;46(4):421-5.
2000: Kunihiro Matsumoto; Katsunori Ohnishi; Takashi Sekine; Hiroki Ueda; Yasumich Yamamoto; Tetsuya Kiyotani; Tetsuya Nakamura; Katsuaki Endo; Yasuhiko Shimizu
Use of a newly developed artificial nerve conduit to assist peripheral nerve regeneration across a long gap in dogs.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000;46(4):415-20.
2000: Yu Liu; Tetsuya Nakamura; Yasumich Yamamoto; Kunihiro Matsumoto; Takashi Sekine; Hiroki Ueda; Yasuhiko Shimizu
Immunosuppressant-free allotransplantation of the trachea: the antigenicity of tracheal grafts can be reduced by removing the epithelium and mixed glands from the graft by detergent treatment.
The Journal of thoracic and cardiovascular surgery 2000;120(1):108-14.
2000: Kunihiro Matsumoto; Katsunori Ohnishi; Tetsuya Kiyotani; Takashi Sekine; Hiroki Ueda; Tetsuya Nakamura; Katsuaki Endo; Yasuhiko Shimizu
Peripheral nerve regeneration across an 80-mm gap bridged by a polyglycolic acid (PGA)-collagen tube filled with laminin-coated collagen fibers: a histological and electrophysiological evaluation of regenerated nerves.
Brain research 2000;868(2):315-28.
2000: Y Nakamura; N Takayama; Takeharu Minamitani; Tomoki Ikuta; Hiroyoshi Ariga; Kunihiro Matsumoto
Primary structure, genomic organization and expression of the major secretory protein of murine epididymis, ME1.
Gene 2000;251(1):55-62.
2000: Hiroya Ishikawa; Mitsuya Shimoda; A Yonekura; K Mishima; Kunihiro Matsumoto; Yutaka Osajima
Unfolding of poly-L-glutamic acid by microbubbling of supercritical carbon dioxide.
Bioscience, biotechnology, and biochemistry 2000;64(6):1295-7.
2000: Takashi Sekine; Tetsuya Nakamura; Yasuhiko Shimizu; Yu Liu; Hiroki Ueda; Kunihiro Matsumoto
Experimental carinal replacement with an Y-shaped collagen-conjugated prosthesis.
The Thoracic and cardiovascular surgeon 2000;48(3):125-9.
2000: Takashi Sekine; Tetsuya Nakamura; Kunihiro Matsumoto; Yu Liu; Hiroki Ueda; Naohisa Tamura; Yasuhiko Shimizu
Carinal reconstruction with a Y-shaped collagen-conjugated prosthesis.
The Journal of thoracic and cardiovascular surgery 2000;119(6):1162-8.
2000: Giichi Takaesu; Satoshi Kishida; A Hiyama; K Yamaguchi; Hiroshi Shibuya; Kenji Irie; Jun Ninomiya-Tsuji; Kunihiro Matsumoto
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
Molecular cell 2000;5(4):649-58.
2000: Toshiro Matsui; Chun-Hui Li; Takashi Tanaka; T Maki; Yutaka Osajima; Kunihiro Matsumoto
Depressor effect of wheat germ hydrolysate and its novel angiotensin I-converting enzyme inhibitory peptide, Ile-Val-Tyr, and the metabolism in rat and human plasma.
Biological & pharmaceutical bulletin 2000;23(4):427-31.
2000: Woong Sun; Hiroshi Funakoshi; Kunihiro Matsumoto; Tadashi Nakamura
A sensitive quantification method for evaluating the level of hepatocyte growth factor and c-met/HGF receptor mRNAs in the nervous system using competitive RT-PCR.
Brain research. Brain research protocols 2000;5(2):190-7.
2000: Kunihiro Matsumoto; Kenichi Hirano; S Nozaki; A Takamoto; Makoto Nishida; Yumiko Nakagawa-Toyama; Mohamed Janabi; T Ohya; Shizuya Yamashita; Yuji Matsuzawa
Expression of macrophage (Mphi) scavenger receptor, CD36, in cultured human aortic smooth muscle cells in association with expression of peroxisome proliferator activated receptor-gamma, which regulates gain of Mphi-like phenotype in vitro, and its implication in atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):1027-32.
2000: K Kishimoto; Kunihiro Matsumoto; Jun Ninomiya-Tsuji
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop.
The Journal of biological chemistry 2000;275(10):7359-64.
2000: Kiichiro Beppu; Akihiko Uchiyama; Takashi Morisaki; Katsumasa Nakamura; Hirokazu Noshiro; Kunihiro Matsumoto; Tetsuya Nakamura; Masao Tanaka; Mitsuo Katano
Elevation of serum hepatocyte growth factor concentration in patients with gastric cancer is mediated by production from tumor tissue.
Anticancer research 2000;20(2B):1263-7.
2000: Yukako Atsumi; Takumi Imai; Kunihiro Matsumoto; Masayoshi Sakuda; Takashi Maeda; Kojiro Kurisu; Satoshi Wakisaka
Effects of different types of injury to the inferior alveolar nerve on the behavior of Schwann cells during the regeneration of periodontal nerve fibers of rat incisor.
Archives of histology and cytology 2000;63(1):43-54.
2000: Shinya Mizuno; Kunihiro Matsumoto; T Kurosawa; Y Mizuno-Horikawa; Tadashi Nakamura
Reciprocal balance of hepatocyte growth factor and transforming growth factor-beta 1 in renal fibrosis in mice.
Kidney international 2000;57(3):937-48.
2000: Motokuni Aoki; Ryuichi Morishita; Yoshiaki Taniyama; Iwao Kida; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Angiogenesis induced by hepatocyte growth factor in non-infarcted myocardium and infarcted myocardium: up-regulation of essential transcription factor for angiogenesis, ets.
Gene therapy 2000;7(5):417-27.
2000: Hiroko Nogami; Hisamichi Aizawa; Kunihiro Matsumoto; Hitoo Nakano; Hiroshi Koto; H Miyazaki; T Hirose; Sankei Nishima; Nobuyuki Hara
Neutrophil elastase inhibitor, ONO-5046 suppresses ozone-induced airway mucus hypersecretion in guinea pigs.
European journal of pharmacology 2000;390(1-2):197-202.
2000: Hiroyasu Inoue; Hisamichi Aizawa; Hitoo Nakano; Kunihiro Matsumoto; K Kuwano; J A Nadel; Nobuyuki Hara
Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs. Possible role of interleukin-8.
American journal of respiratory and critical care medicine 2000;161(1):249-56.
1999: Tomoyuki Sumi; Kunihiro Matsumoto; Yoshimi Takai; Tadashi Nakamura
Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2.
The Journal of cell biology 1999;147(7):1519-32.
1999: Yukako Atsumi; Kunihiro Matsumoto; Masayoshi Sakuda; Takashi Maeda; Kojiro Kurisu; Satoshi Wakisaka
Altered distribution of Schwann cells in the periodontal ligament of the rat incisor following resection of the inferior alveolar nerve: an immunohistochemical study on S-100 proteins.
Brain research 1999;849(1-2):187-95.
1999: Hisamichi Aizawa; M Shigyo; Hitoo Nakano; Kunihiro Matsumoto; Hiroyasu Inoue; Nobuyuki Hara
Effect of the Chinese herbal medicine, Bakumondo-to, on airway hyperresponsiveness induced by ozone exposure in guinea-pigs.
Respirology (Carlton, Vic.) 1999;4(4):349-54.
1999: M Kondo; Keizo Horibe; Yoshiyuki Takahashi; Kunihiro Matsumoto; M Fukuda; J Inaba; Kanefusa Kato; Seiji Kojima; Takaharu Matsuyama
Prognostic value of internal tandem duplication of the FLT3 gene in childhood acute myelogenous leukemia.
Medical and pediatric oncology 1999;33(6):525-9.
1999: Masaki Inagaki; Tobias Schmelzle; K Yamaguchi; Kenji Irie; Michael N Hall; Kunihiro Matsumoto
PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast.
Molecular and cellular biology 1999;19(12):8344-52.
1999: Seiji Hayashi; Ryuichi Morishita; Shun Nakamura; Kazuhiro Yamamoto; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells.
Circulation 1999;100(19 Suppl):II301-8.
1999: Kunihiro Matsumoto; Hisamichi Aizawa; Hiroyasu Inoue; Hiroshi Koto; Hitoo Nakano; Nobuyuki Hara
Role of neutrophil elastase in ozone-induced airway responses in guinea-pigs.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1088-94.
1999: Toshiro Matsui; Kei Tamaya; Kunihiro Matsumoto; Yutaka Osajima; Keiko Uezono; Terukazu Kawasaki
Plasma concentrations of angiotensin metabolites in young male normotensive and mild hypertensive subjects.
Hypertension research : official journal of the Japanese Society of Hypertension 1999;22(4):273-7.
1999: Hisamichi Aizawa; M Shigyo; Kunihiro Matsumoto; Hiroyasu Inoue; Hiroshi Koto; Nobuyuki Hara
PACAP reverses airway hyperresponsiveness induced by ozone exposure in guinea pigs.
Respiration; international review of thoracic diseases 1999;66(6):538-42.
1999: Kazuo Nishimura; M Kitamura; Hidenobu Miura; Norio Nonomura; S Takada; Shiro Takahara; Kunihiro Matsumoto; Tadashi Nakamura; Kiyomi Matsumiya
Prostate stromal cell-derived hepatocyte growth factor induces invasion of prostate cancer cell line DU145 through tumor-stromal interaction.
The Prostate 1999;41(3):145-53.
1999: Tetsuo Moriguchi; K Kawachi; S Kamakura; Norihisa Masuyama; Hiroaki Yamanaka; Kunihiro Matsumoto; A Kikuchi; Eisuke Nishida
Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates.
The Journal of biological chemistry 1999;274(43):30957-62.
1999: Akihiko Uchiyama; Takashi Morisaki; Kiichiro Beppu; M Kojima; Y Matsunari; A Nakatsuka; Kazuhiro Mizumoto; Kunihiro Matsumoto; Tetsuya Nakamura; Masao Tanaka
Hepatocyte growth factor and invasion-stimulatory activity are induced in pleural fluid by surgery in lung cancer patients.
British journal of cancer 1999;81(4):721-6.
1999: Hiroshi Hanafusa; Jun Ninomiya-Tsuji; Norihisa Masuyama; M Nishita; J Fujisawa; Hiroshi Shibuya; Kunihiro Matsumoto; Eisuke Nishida
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression.
The Journal of biological chemistry 1999;274(38):27161-7.
1999: N Matsumoto-Taniura; Kunihiro Matsumoto; Tadashi Nakamura
Prostaglandin production in mouse mammary tumour cells confers invasive growth potential by inducing hepatocyte growth factor in stromal fibroblasts.
British journal of cancer 1999;81(2):194-202.
1999: R Hasina; Kunihiro Matsumoto; N Matsumoto-Taniura; I Kato; Masayoshi Sakuda; Tadashi Nakamura
Autocrine and paracrine motility factors and their involvement in invasiveness in a human oral carcinoma cell line.
British journal of cancer 1999;80(11):1708-17.
1999: Kunihiro Matsumoto; Ryuichi Morishita; Atsushi Moriguchi; Naruya Tomita; Yoshikage Yo; T Nishii; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats.
Hypertension 1999;34(2):279-84.
1999: Yasumich Yamamoto; Tetsuya Nakamura; Yasuhiko Shimizu; Kunihiro Matsumoto; Yukinobu Takimoto; Tetsuya Kiyotani; Takashi Sekine; Hiroki Ueda; Y Liu; Naohisa Tamura
Intrathoracic esophageal replacement in the dog with the use of an artificial esophagus composed of a collagen sponge with a double-layered silicone tube.
The Journal of thoracic and cardiovascular surgery 1999;118(2):276-86.
1999: Kenichi Hirano; Shizuya Yamashita; Yasuhiko Nakagawa; T Ohya; Fumihiko Matsuura; Kosuke Tsukamoto; Yoshihisa Okamoto; Akifumi Matsuyama; Kunihiro Matsumoto; Jun-ichiro Miyagawa; Yuji Matsuzawa
Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions.
Circulation research 1999;85(1):108-16.
1999: T Adachi-Yamada; K Fujimura-Kamada; Yasuyoshi Nishida; Kunihiro Matsumoto
Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing.
Nature 1999;400(6740):166-9.
1999: Yasumich Yamamoto; Tetsuya Nakamura; Yasuhiko Shimizu; Yukinobu Takimoto; Kunihiro Matsumoto; Tetsuya Kiyotani; L Yu; Hiroki Ueda; Takashi Sekine; Naohisa Tamura
Experimental replacement of the thoracic esophagus with a bioabsorbable collagen sponge scaffold supported by a silicone stent in dogs.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1999;45(4):311-6.
1999: Kunihiro Matsumoto; Tetsuya Nakamura; Yasuhiko Shimizu; Hiroki Ueda; Takashi Sekine; Yasumich Yamamoto; Tetsuya Kiyotani; Yukinobu Takimoto
A novel surgical material made from collagen with high mechanical strength: a collagen sandwich membrane.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1999;45(4):288-92.
1999: M Kawasaki; Naoki Hisamoto; Y Iino; M Yamamoto; Jun Ninomiya-Tsuji; Kunihiro Matsumoto
A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons.
The EMBO journal 1999;18(13):3604-15.
1999: K Kosai; Kunihiro Matsumoto; Hiroshi Funakoshi; Tadashi Nakamura
Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice.
Hepatology (Baltimore, Md.) 1999;30(1):151-9.
1999: Tohru Ishitani; Jun Ninomiya-Tsuji; S Nagai; M Nishita; MD Meneghini; Nick Barker; M Waterman; Bruce Bowerman; H Clevers; Hiroshi Shibuya; Kunihiro Matsumoto
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.
Nature 1999;399(6738):798-802.
1999: MD Meneghini; Tohru Ishitani; J Clayton Carter; Naoki Hisamoto; Jun Ninomiya-Tsuji; Chris J Thorpe; Danielle R Hamill; Kunihiro Matsumoto; Bruce Bowerman
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans.
Nature 1999;399(6738):793-7.
1999: Hideo Taniura; Kunihiro Matsumoto; Kunihiko Yoshikawa
Physical and functional interactions of neuronal growth suppressor necdin with p53.
The Journal of biological chemistry 1999;274(23):16242-8.
1999: H Ueda; Yoshiki Sawa; Kunihiro Matsumoto; Satoru Kitagawa-Sakakida; Y Kawahira; Tadashi Nakamura; Yasufumi Kaneda; Hikaru Matsuda
Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart.
The Annals of thoracic surgery 1999;67(6):1726-31.
1999: Ryuichi Morishita; Shun Nakamura; Seiji Hayashi; Yoshiaki Taniyama; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; S Takeshita; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy.
Hypertension 1999;33(6):1379-84.
1999: T Kanesaki; M Saeki; Yasuhiro Ooi; M Suematsu; Kunihiro Matsumoto; Masayoshi Sakuda; K Saito; S Maeda
Morphine prevents peroxynitrite-induced death of human neuroblastoma SH-SY5Y cells through a direct scavenging action.
European journal of pharmacology 1999;372(3):319-24.
1999: Takashi Sekine; Tetsuya Nakamura; Hiroki Ueda; Kunihiro Matsumoto; Yasumich Yamamoto; Yukinobu Takimoto; Tetsuya Kiyotani; Yasuhiko Shimizu
Replacement of the tracheobronchial bifurcation by a newly developed Y-shaped artificial trachea.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1999;45(3):131-4.
1999: A Nakata; Yasuhiko Nakagawa; Makoto Nishida; S Nozaki; Jun-ichiro Miyagawa; T Nakagawa; R Tamura; Kunihiro Matsumoto; K Kameda-Takemura; Shizuya Yamashita; Yuji Matsuzawa
CD36, a novel receptor for oxidized low-density lipoproteins, is highly expressed on lipid-laden macrophages in human atherosclerotic aorta.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1333-9.
1999: Hisamichi Aizawa; Shohei Takata; Hiroyasu Inoue; Kunihiro Matsumoto; Hiroshi Koto; Nobuyuki Hara
Role of nitric oxide released from iNANC neurons in airway responsiveness in cats.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(4):775-80.
1999: Jun Ninomiya-Tsuji; K Kishimoto; A Hiyama; J Inoue; Z Cao; Kunihiro Matsumoto
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.
Nature 1999;398(6724):252-6.
1999: T Adachi-Yamada; M Nakamura; Kenji Irie; Y Tomoyasu; Y Sano; E Mori; S Goto; Naoto Ueno; Yasuyoshi Nishida; Kunihiro Matsumoto
p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesis.
Molecular and cellular biology 1999;19(3):2322-9.
1999: T Yoshimaru; M Shibata; T Fukugomori; Kunihiro Matsumoto
Preparation and characteristics of rumen-bypass microcapsules for improvement of productivity in ruminants.
Journal of agricultural and food chemistry 1999;47(2):554-7.
1999: S Nozaki; Takao Tanaka; Shizuya Yamashita; Koichi Sohmiya; T Yoshizumi; F Okamoto; Yasushi Kitaura; C Kotake; H Nishida; A Nakata; T Nakagawa; Kunihiro Matsumoto; K Kameda-Takemura; Seiji Tadokoro; Yoshiyuki Kurata; Yoshiaki Tomiyama; K Kawamura; Yuji Matsuzawa
CD36 mediates long-chain fatty acid transport in human myocardium: complete myocardial accumulation defect of radiolabeled long-chain fatty acid analog in subjects with CD36 deficiency.
Molecular and cellular biochemistry 1999;192(1-2):129-35.
1999: Masahiro Tahara; Kunihiro Matsumoto; T Nukiwa; Tadashi Nakamura
Hepatocyte growth factor leads to recovery from alcohol-induced fatty liver in rats.
The Journal of clinical investigation 1999;103(3):313-20.
1999: Takao Kondo; Kunihiro Matsumoto; Kenji Sugimoto
Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway.
Molecular and cellular biology 1999;19(2):1136-43.
1999: K Yamaguchi; S Nagai; Jun Ninomiya-Tsuji; M Nishita; Katsuyuki Tamai; Kenji Irie; Naoto Ueno; Eisuke Nishida; Hiroshi Shibuya; Kunihiro Matsumoto
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway.
The EMBO journal 1999;18(1):179-87.
1999: Y Haeuchi; Kunihiro Matsumoto; H Ichikawa; S Maeda
Immunohistochemical demonstration of neuropeptides in the articular disk of the human temporomandibular joint.
Cells, tissues, organs 1999;164(4):205-11.
1999: S Takada; Shiro Takahara; Kazuo Nishimura; Naotsugu Ichimaru; J Hongsi; Yukito Kokado; M Kitamura; Kiyomi Matsumiya; Kunihiro Matsumoto; Tadashi Nakamura; Akihiko Okuyama
Effect of hepatocyte growth factor on tacrolimus-induced nephrotoxicity in spontaneously hypertensive rats.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(1):27-32.
1999: Hiroyasu Inoue; Hisamichi Aizawa; Satoru Fukuyama; Shohei Takata; Kunihiro Matsumoto; M Shigyo; Hiroshi Koto; Nobuyuki Hara
Effect of inhaled glucocorticoid on the cellular profile and cytokine levels in induced sputum from asthmatic patients.
Lung 1999;177(1):53-62.
1998: K Date; Kunihiro Matsumoto; K Kuba; H Shimura; Masaki Tanaka; Tadashi Nakamura
Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor.
Oncogene 1998;17(23):3045-54.
1998: Satoshi Wakisaka; Makoto J Tabata; Takashi Maeda; Kunihiro Matsumoto; Akio Wanaka; H Muramatsu; T Muramatsu; Kojiro Kurisu
Immunohistochemical localization of pleiotrophin and midkine in the lingual epithelium of the adult rat.
Archives of histology and cytology 1998;61(5):475-80.
1998: Shun Nakamura; Ryuichi Morishita; Atsushi Moriguchi; Yoshikage Yo; Y Nakamura; Seiji Hayashi; Kunihiro Matsumoto; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Hepatocyte growth factor as a potential index of complication in diabetes mellitus.
Journal of hypertension 1998;16(12 Pt 2):2019-26.
1998: Yoshikage Yo; Ryuichi Morishita; Shun Nakamura; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells.
Kidney international 1998;54(4):1128-38.
1998: N Takahashi; Hisamichi Aizawa; Hiroyasu Inoue; Kunihiro Matsumoto; Hitoo Nakano; T Hirose; Sankei Nishima; Nobuyuki Hara
Effects of epinastine hydrochloride on cholinergic neuro-effector transmission in canine tracheal smooth muscle.
European journal of pharmacology 1998;358(1):55-61.
1998: Kunihiro Matsumoto; Hisamichi Aizawa; Hiroyasu Inoue; Shohei Takata; M Shigyo; Nobuyuki Hara
Role of adrenergic nervous system in cigarette smoke-induced bronchoconstriction in guinea pigs.
European journal of pharmacology 1998;358(1):49-54.
1998: Tomoki Ikuta; N Sogawa; Hiroyoshi Ariga; T Ikemura; Kunihiro Matsumoto
Structural analysis of mouse tenascin-X: evolutionary aspects of reduplication of FNIII repeats in the tenascin gene family.
Gene 1998;217(1-2):1-13.
1998: Kunihiro Matsumoto; H Kataoka; K Date; Tadashi Nakamura
Cooperative interaction between alpha- and beta-chains of hepatocyte growth factor on c-Met receptor confers ligand-induced receptor tyrosine phosphorylation and multiple biological responses.
The Journal of biological chemistry 1998;273(36):22913-20.
1998: Hisamichi Aizawa; Hiroyasu Inoue; Hitoo Nakano; Kunihiro Matsumoto; M Yoshida; Satoru Fukuyama; Hiroshi Koto; Nobuyuki Hara
Effects of thromboxane A2 antagonist on airway hyperresponsiveness, exhaled nitric oxide, and induced sputum eosinophils in asthmatics.
Prostaglandins, leukotrienes, and essential fatty acids 1998;59(3):185-90.
1998: N Nakano; Ryuichi Morishita; Atsushi Moriguchi; Y Nakamura; Seiji Hayashi; Motokuni Aoki; Iwao Kida; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-beta in blood vessels: potential role of HGF in cardiovascular disease.
Hypertension 1998;32(3):444-51.
1998: Toshiyasu Shimomura; Satoshi Ando; Kunihiro Matsumoto; Kenji Sugimoto
Functional and physical interaction between Rad24 and Rfc5 in the yeast checkpoint pathways.
Molecular and cellular biology 1998;18(9):5485-91.
1998: Kunihiro Matsumoto; Hisamichi Aizawa; Hiroyasu Inoue; Hiroshi Koto; Shohei Takata; M Shigyo; Hitoo Nakano; Nobuyuki Hara
Eosinophilic airway inflammation induced by repeated exposure to cigarette smoke.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(2):387-94.
1998: T Nakagawa; S Nozaki; Makoto Nishida; J M Yakub; Yoshiaki Tomiyama; A Nakata; Kunihiro Matsumoto; Tohru Funahashi; K Kameda-Takemura; Yoshiyuki Kurata; Shizuya Yamashita; Yuji Matsuzawa
Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte-derived macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1998;18(8):1350-7.
1998: Motoshi Suzuki; Kunihiro Matsumoto; T Nakamura; Kiwao Nakano
Stimulation by histamine of TPA-dependent hepatocyte growth factor production in promyelocytic leukemia HL-60 cells.
Bioscience, biotechnology, and biochemistry 1998;62(7):1399-402.
1998: M Shigyo; Hisamichi Aizawa; Hiroyasu Inoue; Kunihiro Matsumoto; Shohei Takata; Nobuyuki Hara
Pituitary adenylate cyclase activating peptide regulates neurally mediated airway responses.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(1):64-70.
1998: Kazuo Nishimura; M Kitamura; S Takada; Norio Nonomura; Akira Tsujimura; Kiyomi Matsumiya; Tsuneharu Miki; Kunihiro Matsumoto; Akihiko Okuyama
Regulation of invasive potential of human prostate cancer cell lines by hepatocyte growth factor.
International journal of urology : official journal of the Japanese Urological Association 1998;5(3):276-81.
1998: Shinya Mizuno; Tsutomu Kurosawa; Kunihiro Matsumoto; Yoko Mizuno-Horikawa; Mitsuhiro Okamoto; Tadashi Nakamura
Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease.
The Journal of clinical investigation 1998;101(9):1827-34.
1998: Kunihiro Matsumoto; T Yamamoto; Hirohisa Kurachi; Yukihiro Nishio; Toshihiro Takeda; H Homma; Ken-ichirou Morishige; A Miyake; Yuji Murata
Human chorionic gonadotropin-alpha gene is transcriptionally activated by epidermal growth factor through cAMP response element in trophoblast cells.
The Journal of biological chemistry 1998;273(14):7800-6.
1998: H Ohmichi; Uichi Koshimizu; Kunihiro Matsumoto; Tadashi Nakamura
Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development.
Development (Cambridge, England) 1998;125(7):1315-24.
1998: K Kosai; Kunihiro Matsumoto; Satoshi Nagata; Yoshihide Tsujimoto; Tadashi Nakamura
Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor.
Biochemical and biophysical research communications 1998;244(3):683-90.
1998: Shun Nakamura; Atsushi Moriguchi; Ryuichi Morishita; Motokuni Aoki; Yoshikage Yo; Seiji Hayashi; N Nakano; Tomohiro Katsuya; S Nakata; S Takami; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension.
Biochemical and biophysical research communications 1998;242(1):238-43.
1998: H Li; H Shimura; Y Aoki; K Date; Kunihiro Matsumoto; Tetsuya Nakamura; Masao Tanaka
Hepatocyte growth factor stimulates the invasion of gallbladder carcinoma cell lines in vitro.
Clinical & experimental metastasis 1998;16(1):74-82.
1998: Yoshikage Yo; Ryuichi Morishita; Kazuhiro Yamamoto; Naruya Tomita; Iwao Kida; Seiji Hayashi; Atsushi Moriguchi; S Kato; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Actions of hepatocyte growth factor as a local modulator in the kidney: potential role in pathogenesis of renal disease.
Kidney international 1998;53(1):50-8.
1997: K Date; Kunihiro Matsumoto; H Shimura; Masaki Tanaka; Tadashi Nakamura
HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor.
FEBS letters 1997;420(1):1-6.
1997: Hisamichi Aizawa; Hiroshi Koto; Hitoo Nakano; Hiroyasu Inoue; Kunihiro Matsumoto; Shohei Takata; M Shigyo; Nobuyuki Hara
The effects of a specific tachykinin receptor antagonist FK-224 on ozone-induced airway hyperresponsiveness and inflammation.
Respirology (Carlton, Vic.) 1997;2(4):261-5.
1997: N Nakano; Atsushi Moriguchi; Ryuichi Morishita; Iwao Kida; Naruya Tomita; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats.
Hypertension 1997;30(6):1448-54.
1997: Kunihiro Matsumoto; Hisamichi Aizawa; Shohei Takata; Hiroyasu Inoue; N Takahashi; Nobuyuki Hara
Nitric oxide derived from sympathetic nerves regulates airway responsiveness to histamine in guinea pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(5):1432-7.
1997: Kunihiro Matsumoto; Tadashi Nakamura
Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration.
Biochemical and biophysical research communications 1997;239(3):639-44.
1997: Kenji Sugimoto; Satoshi Ando; Toshiyasu Shimomura; Kunihiro Matsumoto
Rfc5, a replication factor C component, is required for regulation of Rad53 protein kinase in the yeast checkpoint pathway.
Molecular and cellular biology 1997;17(10):5905-14.
1997: Hiroyasu Inoue; Hisamichi Aizawa; Kunihiro Matsumoto; M Shigyo; Shohei Takata; M Hara; Nobuyuki Hara
Effect of beta 2-agonists on histamine-induced airway microvascular leakage in ozone-exposed guinea pigs.
American journal of respiratory and critical care medicine 1997;156(3 Pt 1):723-7.
1997: Ryuichi Morishita; Jitsuo Higaki; Seiji Hayashi; Yoshikage Yo; Motokuni Aoki; Shun Nakamura; Atsushi Moriguchi; H Matsushita; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara
Role of hepatocyte growth factor in endothelial regulation: prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor.
Diabetologia 1997;40(9):1053-61.
1997: Tadashi Nakamura; Kunihiro Matsumoto; A Kiritoshi; Yasuo Tano; T Nakamura
Induction of hepatocyte growth factor in fibroblasts by tumor-derived factors affects invasive growth of tumor cells: in vitro analysis of tumor-stromal interactions.
Cancer research 1997;57(15):3305-13.
1997: Yasuo Matsuda; Kunihiro Matsumoto; Akira Yamada; T Ichida; H Asakura; Y Komoriya; E Nishiyama; Tadashi Nakamura
Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis.
Hepatology (Baltimore, Md.) 1997;26(1):81-9.
1997: L Beviglia; Kunihiro Matsumoto; C S Lin; Barry L Ziober; Randall H Kramer
Expression of the c-Met/HGF receptor in human breast carcinoma: correlation with tumor progression.
International journal of cancer. Journal international du cancer 1997;74(3):301-9.
1997: T Takahashi; S Aoki; Tadashi Nakamura; Uichi Koshimizu; Kunihiro Matsumoto; T Nakamura
Xenopus LIM motif-containing protein kinase, Xlimk1, is expressed in the developing head structure of the embryo.
Developmental dynamics : an official publication of the American Association of Anatomists 1997;209(2):196-205.
1997: Shunji Aoki; Kiyohisa Takahashi; Kunihiro Matsumoto; Tadashi Nakamura
Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo.
Biochemical and biophysical research communications 1997;234(1):8-14.
1997: Minoru Funakoshi; H Sikder; H Ebihara; K Irie; Katsunori Sugimoto; Kunihiro Matsumoto; Tim Hunt; Takeharu Nishimoto; Hideki Kobayashi
Xenopus cyclin A1 can associate with Cdc28 in budding yeast, causing cell-cycle arrest with an abnormal distribution of nuclear DNA.
Genes to cells : devoted to molecular & cellular mechanisms 1997;2(5):329-43.
1997: Young-Mi Lim; Leo Tsuda; Y H Inoue; Kenji Irie; T Adachi-Yamada; M Hata; Y Nishi; Kunihiro Matsumoto; Yasuyoshi Nishida
Dominant mutations of Drosophila MAP kinase kinase and their activities in Drosophila and yeast MAP kinase cascades.
Genetics 1997;146(1):263-73.
1997: Y Watanabe; Giichi Takaesu; M Hagiwara; Kenji Irie; Kunihiro Matsumoto
Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.
Molecular and cellular biology 1997;17(5):2615-23.
1997: K Shirakabe; K Yamaguchi; Hiroshi Shibuya; Kazuhiro Irie; S Matsuda; Tetsuo Moriguchi; Y Gotoh; Kunihiro Matsumoto; Eisuke Nishida
TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase.
The Journal of biological chemistry 1997;272(13):8141-4.
1997: Kenji Takai; Junichi Hara; Kunihiro Matsumoto; Gaku Hosoi; Yuko Osugi; Akio Tawa; Shintaro Okada; Tadashi Nakamura
Hepatocyte growth factor is constitutively produced by human bone marrow stromal cells and indirectly promotes hematopoiesis.
Blood 1997;89(5):1560-5.
1997: Ryuichi Morishita; Motokuni Aoki; Shun Nakamura; H Matsushita; Naruya Tomita; Seiji Hayashi; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of a novel vascular modulator, hepatocyte growth factor (HGF), in cardiovascular disease: characterization and regulation of local HGF system.
Journal of atherosclerosis and thrombosis 1997;4(1):12-9.
1997: Kunihiro Matsumoto; Tadashi Nakamura
HGF: its organotrophic role and therapeutic potential.
Ciba Foundation symposium 1997;212():198-211; discussion 211-4.
1997: M Shigyo; Hisamichi Aizawa; Hiroshi Koto; Kunihiro Matsumoto; Shohei Takata; Nobuyuki Hara
Pre- and post-junctional effects of VIP-like peptides in guinea pig tracheal smooth muscle.
Respiration; international review of thoracic diseases 1997;64(1):59-65.
1997: Ryuichi Morishita; Shun Nakamura; Y Nakamura; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; Yoshikage Yo; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of an endothelium-specific growth factor, hepatocyte growth factor, on endothelial damage in diabetes.
Diabetes 1997;46(1):138-42.