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Ralf Mattes

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Chemicals & Drugs

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Gene Expression Regulation, Bacterial

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Publications

TOP 3
Alexandra Lipski; Ralf Mattes; Stéphanie Ravaud; Moez Rhimi; Xavier Robert; Hildegard Watzlawick; Richard Haser; Nushin Aghajari
Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity.
Romain Merceron; Hildegard Watzlawick; Marine Foucault; Richard Haser; Ralf Mattes; Patrice Gouet
The molecular mechanism of thermostable α-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies.
Hildegard Watzlawick; Ralf Mattes
Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45.

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All Publications

2013: Alexandra Lipski; Ralf Mattes; Stéphanie Ravaud; Moez Rhimi; Xavier Robert; Hildegard Watzlawick; Richard Haser; Nushin Aghajari
Mutations inducing an active-site aperture in Rhizobium sp. sucrose isomerase confer hydrolytic activity.
Acta crystallographica. Section D, Biological crystallography 2013;69(Pt 2):298-307.
2012: Romain Merceron; Hildegard Watzlawick; Marine Foucault; Richard Haser; Ralf Mattes; Patrice Gouet
The molecular mechanism of thermostable α-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies.
The Journal of biological chemistry 2012;287(47):39642-52.
2009: Hildegard Watzlawick; Ralf Mattes
Gene cloning, protein characterization, and alteration of product selectivity for the trehalulose hydrolase and trehalulose synthase from "Pseudomonas mesoacidophila" MX-45.
Applied and environmental microbiology 2009;75(22):7026-36.
2009: Gaël Placier; Hildegard Watzlawick; Claude Rabiller; Ralf Mattes
Evolved beta-galactosidases from Geobacillus stearothermophilus with improved transgalactosylation yield for galacto-oligosaccharide production.
Applied and environmental microbiology 2009;75(19):6312-21.
2009: Stéphanie Ravaud; Xavier Robert; Hildegard Watzlawick; Richard Haser; Ralf Mattes; Nushin Aghajari
Structural determinants of product specificity of sucrose isomerases.
FEBS letters 2009;583(12):1964-8.
2007: Stéphanie Ravaud; Xavier Robert; Hildegard Watzlawick; Richard Haser; Ralf Mattes; Nushin Aghajari
Trehalulose synthase native and carbohydrate complexed structures provide insights into sucrose isomerization.
The Journal of biological chemistry 2007;282(38):28126-36.
2006: Andreas Keck; Doris Conradt; Anette Mahler; Andreas Stolz; Ralf Mattes; Joachim Klein
Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6.
Microbiology (Reading, England) 2006;152(Pt 7):1929-40.
2006: M Foucault; Hildegard Watzlawick; Ralf Mattes; Richard Haser; Patrice Gouet
Crystallization and preliminary X-ray diffraction studies of two thermostable alpha-galactosidases from glycoside hydrolase family 36.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 2):100-3.
2006: Stéphanie Ravaud; Hildegard Watzlawick; Richard Haser; Ralf Mattes; Nushin Aghajari
Overexpression, purification, crystallization and preliminary diffraction studies of the Protaminobacter rubrum sucrose isomerase SmuA.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 1):74-6.
2005: Christoph Kiziak; Doris Conradt; Andreas Stolz; Ralf Mattes; Joachim Klein
Nitrilase from Pseudomonas fluorescens EBC191: cloning and heterologous expression of the gene and biochemical characterization of the recombinant enzyme.
Microbiology (Reading, England) 2005;151(Pt 11):3639-48.
2005: Stéphanie Ravaud; Hildegard Watzlawick; Richard Haser; Ralf Mattes; Nushin Aghajari
Expression, purification, crystallization and preliminary X-ray crystallographic studies of the trehalulose synthase MutB from Pseudomonas mesoacidophila MX-45.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):100-3.
2003: Ute Heinemann; Dirk Engels; Sibylle Bürger; Christoph Kiziak; Ralf Mattes; Andreas Stolz
Cloning of a nitrilase gene from the cyanobacterium Synechocystis sp. strain PCC6803 and heterologous expression and characterization of the encoded protein.
Applied and environmental microbiology 2003;69(8):4359-66.
2002: Andreas Keck; Jörg Rau; Thorsten Reemtsma; Ralf Mattes; Andreas Stolz; Joachim Klein
Identification of quinoide redox mediators that are formed during the degradation of naphthalene-2-sulfonate by Sphingomonas xenophaga BN6.
Applied and environmental microbiology 2002;68(9):4341-9.
2002: Olafur Fridjonsson; Hildegard Watzlawick; Ralf Mattes
Thermoadaptation of alpha-galactosidase AgaB1 in Thermus thermophilus.
Journal of bacteriology 2002;184(12):3385-91.
2001: M Hils; P Münch; Josef Altenbuchner; Christoph Syldatk; Ralf Mattes
Cloning and characterization of genes from Agrobacterium sp. IP I-671 involved in hydantoin degradation.
Applied microbiology and biotechnology 2001;57(5-6):680-8.
2001: Olafur Fridjonsson; Ralf Mattes
Production of recombinant alpha-galactosidases in Thermus thermophilus.
Applied and environmental microbiology 2001;67(9):4192-8.
2001: A Wiese; Christoph Syldatk; Ralf Mattes; Josef Altenbuchner
Organization of genes responsible for the stereospecific conversion of hydantoins to alpha-amino acids in Arthrobacter aurescens DSM 3747.
Archives of microbiology 2001;176(3):187-96.
2001: Ralf Mattes
The production of improved tissue-type plasminogen activator in Escherichia coli.
Seminars in thrombosis and hemostasis 2001;27(4):325-36.
2001: A Wiese; B Wilms; Christoph Syldatk; Ralf Mattes; Josef Altenbuchner
Cloning, nucleotide sequence and expression of a hydantoinase and carbamoylase gene from Arthrobacter aurescens DSM 3745 in Escherichia coli and comparison with the corresponding genes from Arthrobacter aurescens DSM 3747.
Applied microbiology and biotechnology 2001;55(6):750-7.
2001: B Wilms; Achim Hauck; Matthias Reuss; Christoph Syldatk; Ralf Mattes; Martin Siemann; Josef Altenbuchner
High-cell-density fermentation for production of L-N-carbamoylase using an expression system based on the Escherichia coli rhaBAD promoter.
Biotechnology and bioengineering 2001;73(2):95-103.
2001: B Wilms; A Wiese; Christoph Syldatk; Ralf Mattes; Josef Altenbuchner
Development of an Escherichia coli whole cell biocatalyst for the production of L-amino acids.
Journal of biotechnology 2001;86(1):19-30.
2000: Jörg F Rippmann; Klaus Pfizenmaier; Ralf Mattes; Wolfgang J Rettig; Dieter Moosmayer
Fusion of the tissue factor extracellular domain to a tumour stroma specific single-chain fragment variable antibody results in an antigen-specific coagulation-promoting molecule.
The Biochemical journal 2000;349 Pt 3():805-12.
2000: A Wiese; M Pietzsch; Christoph Syldatk; Ralf Mattes; Josef Altenbuchner
Hydantoin racemase from Arthrobacter aurescens DSM 3747: heterologous expression, purification and characterization.
Journal of biotechnology 2000;80(3):217-30.
2000: Olafur Fridjonsson; Hildegard Watzlawick; Ralf Mattes
The structure of the alpha-galactosidase gene loci in Thermus brockianus ITI360 and Thermus thermophilus TH125.
Extremophiles : life under extreme conditions 2000;4(1):23-33.
2000: M Pietzsch; A Wiese; K Ragnitz; B Wilms; Josef Altenbuchner; Ralf Mattes; Christoph Syldatk
Purification of recombinant hydantoinase and L-N-carbamoylase from Arthrobacter aurescens expressed in Escherichia coli: comparison of wild-type and genetically modified proteins.
Journal of chromatography. B, Biomedical sciences and applications 2000;737(1-2):179-86.
1999: A Habenicht; H Motejadded; M Kiess; A Wegerer; Ralf Mattes
Xylose utilisation: cloning and characterisation of the xylitol dehydrogenase from Galactocandida mastotermitis.
Biological chemistry 1999;380(12):1405-11.
1999: B Häcker; A Habenicht; M Kiess; Ralf Mattes
Xylose utilisation: cloning and characterisation of the Xylose reductase from Candida tenuis.
Biological chemistry 1999;380(12):1395-403.
1999: Olafur Fridjonsson; Hildegard Watzlawick; A Gehweiler; T Rohrhirsch; Ralf Mattes
Cloning of the gene encoding a novel thermostable alpha-galactosidase from Thermus brockianus ITI360.
Applied and environmental microbiology 1999;65(9):3955-63.
1999: D Rother; Ralf Mattes; Josef Altenbuchner
Purification and characterization of MerR, the regulator of the broad-spectrum mercury resistance genes in Streptomyces lividans 1326.
Molecular & general genetics : MGG 1999;262(1):154-62.
1999: Olafur Fridjonsson; Hildegard Watzlawick; A Gehweiler; Ralf Mattes
Thermostable alpha-galactosidase from Bacillus stearothermophilus NUB3621: cloning, sequencing and characterization.
FEMS microbiology letters 1999;176(1):147-53.
1999: Christoph Syldatk; Oliver May; Josef Altenbuchner; Ralf Mattes; Martin Siemann
Microbial hydantoinases--industrial enzymes from the origin of life?
Applied microbiology and biotechnology 1999;51(3):293-309.
1999: B Wilms; A Wiese; Christoph Syldatk; Ralf Mattes; Josef Altenbuchner; M Pietzsch
Cloning, nucleotide sequence and expression of a new L-N-carbamoylase gene from Arthrobacter aurescens DSM 3747 in E. coli.
Journal of biotechnology 1999;68(2-3):101-13.
1998: Jörg F Rippmann; M Klein; Christian Hoischen; B Brocks; Wolfgang J Rettig; Johannes Gumpert; Klaus Pfizenmaier; Ralf Mattes; Dieter Moosmayer
Procaryotic expression of single-chain variable-fragment (scFv) antibodies: secretion in L-form cells of Proteus mirabilis leads to active product and overcomes the limitations of periplasmic expression in Escherichia coli.
Applied and environmental microbiology 1998;64(12):4862-9.
1998: P Brünker; M Hils; Josef Altenbuchner; Ralf Mattes
The mannitol utilization genes of Pseudomonas fluorescens are regulated by an activator: cloning, nucleotide sequence and expression of the mtlR gene.
Gene 1998;215(1):19-27.
1998: J Klein; Ralf Mattes
Enzyme-complemented activatorsorbent assay (ECASA): genetic engineering for enzyme-linked immunosorbent assay-type mercuric ion detection.
Analytical biochemistry 1998;260(2):173-82.
1998: Oliver May; A Habenicht; Ralf Mattes; Christoph Syldatk; Martin Siemann
Molecular evolution of hydantoinases.
Biological chemistry 1998;379(6):743-7.
1998: Oliver May; Martin Siemann; M Pietzsch; M Kiess; Ralf Mattes; Christoph Syldatk
Substrate-dependent enantioselectivity of a novel hydantoinase from Arthrobacter aurescens DSM 3745: purification and characterization as new member of cyclic amidases.
Journal of biotechnology 1998;61(1):1-13.
1998: J Klein; Josef Altenbuchner; Ralf Mattes
Nucleic acid and protein elimination during the sugar manufacturing process of conventional and transgenic sugar beets.
Journal of biotechnology 1998;60(3):145-53.
1998: P Brünker; Josef Altenbuchner; Ralf Mattes
Structure and function of the genes involved in mannitol, arabitol and glucitol utilization from Pseudomonas fluorescens DSM50106.
Gene 1998;206(1):117-26.
1997: Andreas Keck; Joachim Klein; M Kudlich; Andreas Stolz; Hans-Joachim Knackmuss; Ralf Mattes
Reduction of azo dyes by redox mediators originating in the naphthalenesulfonic acid degradation pathway of Sphingomonas sp. strain BN6.
Applied and environmental microbiology 1997;63(9):3684-90.
1997: P Brünker; Josef Altenbuchner; K D Kulbe; Ralf Mattes
Cloning, nucleotide sequence and expression of a mannitol dehydrogenase gene from Pseudomonas fluorescens DSM 50106 in Escherichia coli.
Biochimica et biophysica acta 1997;1351(1-2):157-67.
1997: J Klein; Josef Altenbuchner; Ralf Mattes
Genetically modified Escherichia coli for colorimetric detection of inorganic and organic Hg compounds.
EXS 1997;80():133-51.
1996: P Brünker; D Rother; R Sedlmeier; J Klein; Ralf Mattes; Josef Altenbuchner
Regulation of the operon responsible for broad-spectrum mercury resistance in Streptomyces lividans 1326.
Molecular & general genetics : MGG 1996;251(3):307-15.
1995: I Pelletier; Josef Altenbuchner; Ralf Mattes
A catalytic triad is required by the non-heme haloperoxidases to perform halogenation.
Biochimica et biophysica acta 1995;1250(2):149-57.