FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brian Matthews

Research Profile

Concepts & Ideas

Chemicals & Drugs

Living Beings

Phenomena

Physiology

Co-author Network

Publications

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brian Matthews (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Brian W Matthews
The Bragg legacy: early days in macromolecular crystallography.
Acta crystallographica. Section A, Foundations of crystallography 2013;69(Pt 1):34-6.
2012: Douglas H Juers; Brian W Matthews; Reuben E Huber
LacZ β-galactosidase: structure and function of an enzyme of historical and molecular biological importance.
Protein science : a publication of the Protein Society 2012;21(12):1792-807.
2012: Brian W Matthews
Proteins under pressure.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(18):6792-3.
2011: Brian W Matthews
Stoichiometry versus hydrophobicity in protein folding.
Journal of biomolecular structure & dynamics 2011;28(4):589-91; discussion 669-674.
2010: Brian W Matthews
Peripatetic proteins.
Protein science : a publication of the Protein Society 2010;19(7):1279-80.
2010: Walter A Baase; Lijun Liu; Dale E Tronrud; Brian W Matthews
Lessons from the lysozyme of phage T4.
Protein science : a publication of the Protein Society 2010;19(4):631-41.
2009: Lijun Liu; Walter A Baase; Miya M Michael; Brian W Matthews
Use of stabilizing mutations to engineer a charged group within a ligand-binding hydrophobic cavity in T4 lysozyme.
Biochemistry 2009;48(37):8842-51.
2009: Douglas H Juers; Beatrice Rob; Megan L Dugdale; Nastaron Rahimzadeh; Clarence Giang; Michelle Lee; Brian W Matthews; Reuben E Huber
Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein science : a publication of the Protein Society 2009;18(6):1281-92.
2009: Brian W Matthews
Racemic crystallography--easy crystals and easy structures: what's not to like?
Protein science : a publication of the Protein Society 2009;18(6):1135-8.
2009: Blaine Mooers; Walter A Baase; Jonathan W Wray; Brian W Matthews
Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme.
Protein science : a publication of the Protein Society 2009;18(5):871-80.
2009: Blaine Mooers; Dale E Tronrud; Brian W Matthews
Evaluation at atomic resolution of the role of strain in destabilizing the temperature-sensitive T4 lysozyme mutant Arg 96 --> His.
Protein science : a publication of the Protein Society 2009;18(5):863-70.
2009: Brian W Matthews; Lijun Liu
A review about nothing: are apolar cavities in proteins really empty?
Protein science : a publication of the Protein Society 2009;18(3):494-502.
2009: Lijun Liu; Walter A Baase; Brian W Matthews
Halogenated benzenes bound within a non-polar cavity in T4 lysozyme provide examples of I...S and I...Se halogen-bonding.
Journal of molecular biology 2009;385(2):595-605.
2009: Lijun Liu; Adam J V Marwitz; Brian W Matthews; Shih-Yuan Liu
Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme.
Angewandte Chemie (International ed. in English) 2009;48(37):6817-9.
2009: Dale E Tronrud; Brian W Matthews
Sorting the chaff from the wheat at the PDB.
Protein science : a publication of the Protein Society 2009;18(1):2-5.
2008: Nozomi Ando; Buz Barstow; Walter A Baase; Andrew Fields; Brian W Matthews; Sol M Gruner
Structural and thermodynamic characterization of T4 lysozyme mutants and the contribution of internal cavities to pressure denaturation.
Biochemistry 2008;47(42):11097-109.
2008: Lijun Liu; Michael L Quillin; Brian W Matthews
Use of experimental crystallographic phases to examine the hydration of polar and nonpolar cavities in T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14406-11.
2008: Anthony Addlagatta; Leslie Gay; Brian W Matthews
Structural basis for the unusual specificity of Escherichia coli aminopeptidase N.
Biochemistry 2008;47(19):5303-11.
2007: Douglas H Juers; Jeffrey Lovelace; Henry D Bellamy; Edward H Snell; Brian W Matthews; Gloria E. Borgstahl
Changes to crystals of Escherichia coli beta-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 11):1139-53.
2007: Brian W Matthews
Protein Structure Initiative: getting into gear.
Nature structural & molecular biology 2007;14(6):459-60.
2007: Brian W Matthews
Five retracted structure reports: inverted or incorrect?
Protein science : a publication of the Protein Society 2007;16(6):1013-6.
2007: Marcus D Collins; Michael L Quillin; Gerhard Hummer; Brian W Matthews; Sol M Gruner
Structural rigidity of a large cavity-containing protein revealed by high-pressure crystallography.
Journal of molecular biology 2007;367(3):752-63.
2006: Michael L Quillin; Paul T Wingfield; Brian W Matthews
Determination of solvent content in cavities in IL-1beta using experimentally phased electron density.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19749-53.
2006: Xiaoyi Hu; Anthony Addlagatta; Jun Lu; Brian W Matthews; Jun Lu
Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(48):18148-53.
2006: Anthony Addlagatta; Leslie Gay; Brian W Matthews
Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(36):13339-44.
2006: Anthony Addlagatta; Brian W Matthews
Structure of the angiogenesis inhibitor ovalicin bound to its noncognate target, human Type 1 methionine aminopeptidase.
Protein science : a publication of the Protein Society 2006;15(8):1842-8.
2006: Xiaoyi Hu; Anthony Addlagatta; Brian W Matthews; Jun O Liu
Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases.
Angewandte Chemie (International ed. in English) 2006;45(23):3772-5.
2006: Martin Sagermann; Walter A Baase; Brian W Matthews
Sequential reorganization of beta-sheet topology by insertion of a single strand.
Protein science : a publication of the Protein Society 2006;15(5):1085-92.
2006: Mohammad S Yousef; Nicole Bischoff; Collin M Dyer; Walter A Baase; Brian W Matthews
Guanidinium derivatives bind preferentially and trigger long-distance conformational changes in an engineered T4 lysozyme.
Protein science : a publication of the Protein Society 2006;15(4):853-61.
2006: Zachary A. Wood; Larry H Weaver; Patrick Brown; Dorothy Beckett; Brian W Matthews
Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution.
Journal of molecular biology 2006;357(2):509-23.
2006: Blaine Mooers; Brian W Matthews
Extension to 2268 atoms of direct methods in the ab initio determination of the unknown structure of bacteriophage P22 lysozyme.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 2):165-76.
2005: Douglas H Juers; Jaeseung Kim; Brian W Matthews; Scott McN Sieburth
Structural analysis of silanediols as transition-state-analogue inhibitors of the benchmark metalloprotease thermolysin.
Biochemistry 2005;44(50):16524-8.
2005: Anthony Addlagatta; Xiaoyi Hu; Jun O Liu; Brian W Matthews
Structural basis for the functional differences between type I and type II human methionine aminopeptidases.
Biochemistry 2005;44(45):14741-9.
2005: Marcus D Collins; Gerhard Hummer; Michael L Quillin; Brian W Matthews; Sol M Gruner
Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(46):16668-71.
2005: Hervé Desvaux; Lionel Dubois; Gaspard Huber; Michael L Quillin; Patrick Berthault; Brian W Matthews
Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy.
Journal of the American Chemical Society 2005;127(33):11676-83.
2005: Brian W Matthews
The structure of E. coli beta-galactosidase.
Comptes rendus biologies 2005;328(6):549-56.
2005: Anthony Addlagatta; Michael L Quillin; Omonike Omotoso; Jun O Liu; Brian W Matthews
Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
Biochemistry 2005;44(19):7166-74.
2005: Mohammad S Yousef; Brian W Matthews
Structural basis of Prospero-DNA interaction: implications for transcription regulation in developing cells.
Structure (London, England : 1993) 2005;13(4):601-7.
2005: Gerard J. Ostheimer; Haralambos Hadjivassiliou; Haralambos Hadjivasiliou; Daniel P Kloer; Alice Barkan; Brian W Matthews
Structural analysis of the group II intron splicing factor CRS2 yields insights into its protein and RNA interaction surfaces.
Journal of molecular biology 2005;345(1):51-68.
2004: Blaine Mooers; Brian W Matthews
Use of an ion-binding site to bypass the 1000-atom limit to structure determination by direct methods.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1726-37.
2004: Molly M He; Zachary A. Wood; Walter A Baase; Hong Xiao; Brian W Matthews
Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation.
Protein science : a publication of the Protein Society 2004;13(10):2716-24.
2004: Collin M Dyer; Michael L Quillin; Andres Campos; Justine Lu; Megan M McEvoy; Andrew C Hausrath; Edwin M Westbrook; Philip Matsumura; Brian W Matthews; Frederick W Dahlquist
Structure of the constitutively active double mutant CheYD13K Y106W alone and in complex with a FliM peptide.
Journal of molecular biology 2004;342(4):1325-35.
2004: Mohammad S Yousef; Walter A Baase; Brian W Matthews
Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11583-6.
2004: Richard Kingston; Damon J Hamel; Leslie Gay; Frederick W Dahlquist; Brian W Matthews
Structural basis for the attachment of a paramyxoviral polymerase to its template.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(22):8301-6.
2004: Douglas H Juers; Brian W Matthews
Cryo-cooling in macromolecular crystallography: advantages, disadvantages and optimization.
Quarterly reviews of biophysics 2004;37(2):105-19.
2004: Binqing Q Wei; Larry H Weaver; Anna Maria Ferrari; Brian W Matthews; Brian Shoichet
Testing a flexible-receptor docking algorithm in a model binding site.
Journal of molecular biology 2004;337(5):1161-82.
2004: Douglas H Juers; Brian W Matthews
The role of solvent transport in cryo-annealing of macromolecular crystals.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 3):412-21.
2004: Martin Sagermann; Walter A Baase; Blaine Mooers; Leslie Gay; Brian W Matthews
Relocation or duplication of the helix A sequence of T4 lysozyme causes only modest changes in structure but can increase or decrease the rate of folding.
Biochemistry 2004;43(5):1296-301.
2004: Andrew B Carmel; Brian W Matthews
Crystal structure of the BstDEAD N-terminal domain: a novel DEAD protein from Bacillus stearothermophilus.
RNA (New York, N.Y.) 2004;10(1):66-74.
2003: Douglas H Juers; Shamina Hakda; Brian W Matthews; Reuben E Huber
Structural basis for the altered activity of Gly794 variants of Escherichia coli beta-galactosidase.
Biochemistry 2003;42(46):13505-11.
2003: Michael L Quillin; Brian W Matthews
Selling candles in a post-Edison world: phasing with noble gases bound within engineered sites.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 11):1930-4.
2003: Andrew B Carmel; Brian W Matthews
Purification, crystallization and preliminary X-ray analysis of the novel DEAD protein BstDEAD from Bacillus stearothermophilus.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 10):1869-70.
2003: Blaine Mooers; Deepshikha Datta; Walter A Baase; Eric S Zollars; Stephen L Mayo; Brian W Matthews
Repacking the Core of T4 lysozyme by automated design.
Journal of molecular biology 2003;332(3):741-56.
2003: Martin Sagermann; Leslie Gay; Brian W Matthews
Long-distance conformational changes in a protein engineered by modulated sequence duplication.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9191-5.
2003: Glen K Shoemaker; Douglas H Juers; Jennifer M L Coombs; Brian W Matthews; Douglas B Craig
Crystallization of beta-galactosidase does not reduce the range of activity of individual molecules.
Biochemistry 2003;42(6):1707-10.
2003: Brian W Matthews
Transformations in structural biology: a personal view.
Methods in enzymology 2003;368():3-11.
2003: Nadine C Gassner; Walter A Baase; Blaine Mooers; Robert D Busam; Larry H Weaver; Joel D Lindstrom; Michael L Quillin; Brian W Matthews
Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability.
Biophysical chemistry 2003;100(1-3):325-40.
2002: Xue-jun Zhang; Walter A Baase; Brian W Matthews
A helix initiation signal in T4 lysozyme identified by polyalanine mutagenesis.
Biophysical chemistry 2002;101-102():43-56.
2002: W Todd Lowther; Brian W Matthews
Metalloaminopeptidases: common functional themes in disparate structural surroundings.
Chemical reviews 2002;102(12):4581-608.
2002: Gerard J. Ostheimer; Alice Barkan; Brian W Matthews
Crystal structure of E. coli YhbY: a representative of a novel class of RNA binding proteins.
Structure (London, England : 1993) 2002;10(11):1593-601.
2002: Jodi M Ryter; Chris Q Doe; Brian W Matthews
Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain.
Structure (London, England : 1993) 2002;10(11):1541-9.
2002: Binqing Q Wei; Walter A Baase; Larry H Weaver; Brian W Matthews; Brian Shoichet
A model binding site for testing scoring functions in molecular docking.
Journal of molecular biology 2002;322(2):339-55.
2002: Andrew C Hausrath; Brian W Matthews
Thermolysin in the absence of substrate has an open conformation.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 6 Pt 2):1002-7.
2002: W Todd Lowther; Herbert Weissbach; Frantzy Etienne; Nathan Brot; Brian W Matthews
The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB.
Nature structural biology 2002;9(5):348-52.
2002: Martin Sagermann; Brian W Matthews
Crystal structures of a T4-lysozyme duplication-extension mutant demonstrate that the highly conserved beta-sheet region has low intrinsic folding propensity.
Journal of molecular biology 2002;316(4):931-40.
2002: Martin Sagermann; Lars-Göran Mårtensson; Walter A Baase; Brian W Matthews
A test of proposed rules for helix capping: implications for protein design.
Protein science : a publication of the Protein Society 2002;11(3):516-21.
2002: Michael L Quillin; Brian W Matthews
Generation of noble-gas binding sites for crystallographic phasing using site-directed mutagenesis.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 1):97-103.
2001: Andrew C Hausrath; Roderick A Capaldi; Brian W Matthews
The conformation of the epsilon- and gamma-subunits within the Escherichia coli F(1) ATPase.
The Journal of biological chemistry 2001;276(50):47227-32.
2001: Douglas H Juers; T D Heightman; A Vasella; John McCarter; L Mackenzie; S G Withers; Brian W Matthews
A structural view of the action of Escherichia coli (lacZ) beta-galactosidase.
Biochemistry 2001;40(49):14781-94.
2001: Larry H Weaver; Keehwan Kwon; Dorothy Beckett; Brian W Matthews
Competing protein:protein interactions are proposed to control the biological switch of the E coli biotin repressor.
Protein science : a publication of the Protein Society 2001;10(12):2618-22.
2001: Wendy A. Breyer; Brian W Matthews
A structural basis for processivity.
Protein science : a publication of the Protein Society 2001;10(9):1699-711.
2001: Douglas H Juers; Brian W Matthews
Reversible lattice repacking illustrates the temperature dependence of macromolecular interactions.
Journal of molecular biology 2001;311(4):851-62.
2001: Martin Sagermann; Tom H Stevens; Brian W Matthews
Crystal structure of the regulatory subunit H of the V-type ATPase of Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7134-9.
2001: Larry H Weaver; Keehwan Kwon; Dorothy Beckett; Brian W Matthews
Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6045-50.
2001: J Xu; Walter A Baase; Michael L Quillin; EP Baldwin; Brian W Matthews
Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme.
Protein science : a publication of the Protein Society 2001;10(5):1067-78.
2000: Wendy A. Breyer; Brian W Matthews
Structure of Escherichia coli exonuclease I suggests how processivity is achieved.
Nature structural biology 2000;7(12):1125-8.
2000: W Todd Lowther; Nathan Brot; Herbert Weissbach; Brian W Matthews
Structure and mechanism of peptide methionine sulfoxide reductase, an "anti-oxidation" enzyme.
Biochemistry 2000;39(44):13307-12.
2000: Michael L Quillin; Wendy A. Breyer; Ian J Griswold; Brian W Matthews
Size versus polarizability in protein-ligand interactions: binding of noble gases within engineered cavities in phage T4 lysozyme.
Journal of molecular biology 2000;302(4):955-77.
2000: Douglas H Juers; Raymond Jacobsonr; D Wigley; X J Zhang; Reuben E Huber; Dale E Tronrud; Brian W Matthews
High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation.
Protein science : a publication of the Protein Society 2000;9(9):1685-99.
2000: M M He; Susan L Clugston; John F Honek; Brian W Matthews
Determination of the structure of Escherichia coli glyoxalase I suggests a structural basis for differential metal activation.
Biochemistry 2000;39(30):8719-27.
2000: I P Korndörfer; W D Fessner; Brian W Matthews
The structure of rhamnose isomerase from Escherichia coli and its relation with xylose isomerase illustrates a change between inter and intra-subunit complementation during evolution.
Journal of molecular biology 2000;300(4):917-33.
2000: Michael L Quillin; Brian W Matthews
Accurate calculation of the density of proteins.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 7):791-4.
2000: W Todd Lowther; Nathan Brot; Herbert Weissbach; John F Honek; Brian W Matthews
Thiol-disulfide exchange is involved in the catalytic mechanism of peptide methionine sulfoxide reductase.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6463-8.
2000: J W Wray; Walter A Baase; Gerard J. Ostheimer; X J Zhang; Brian W Matthews
Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site.
Protein engineering 2000;13(5):313-21.
2000: Martin Sagermann; Brian W Matthews
Cloning, expression and crystallization of VMA13p, an essential subunit of the vacuolar H+-ATPase of Saccharomyces cerevisiae.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 4):475-7.
2000: W Todd Lowther; Brian W Matthews
Structure and function of the methionine aminopeptidases.
Biochimica et biophysica acta 2000;1477(1-2):157-67.
2000: P B Rupert; A K M M Mollah; Michael C Mossing; Brian W Matthews
The structural basis for enhanced stability and reduced DNA binding seen in engineered second-generation Cro monomers and dimers.
Journal of molecular biology 2000;296(4):1079-90.
2000: R Liu; Walter A Baase; Brian W Matthews
The introduction of strain and its effects on the structure and stability of T4 lysozyme.
Journal of molecular biology 2000;295(1):127-45.
2000: G Yang; Ciro Cecconi; Walter A Baase; I R Vetter; Wendy A. Breyer; J A Haack; Brian W Matthews; Frederick W Dahlquist; Carlos Bustamante
Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(1):139-44.
2000: I P Korndörfer; J Salerno; DH Jing; Brian W Matthews
Crystallization and preliminary X-ray analysis of a bacteriophage T4 primase fragment.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 1):95-7.
1999: Nadine C Gassner; Brian W Matthews
Use of differentially substituted selenomethionine proteins in X-ray structure determination.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 12):1967-70.
1999: Andrew C Hausrath; G Grüber; Brian W Matthews; Roderick A Capaldi
Structural features of the gamma subunit of the Escherichia coli F(1) ATPase revealed by a 4.4-A resolution map obtained by x-ray crystallography.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13697-702.
1999: Nadine C Gassner; Walter A Baase; Andrew C Hausrath; Brian W Matthews
Substitution with selenomethionine can enhance the stability of methionine-rich proteins.
Journal of molecular biology 1999;294(1):17-20.
1999: W Todd Lowther; Y Zhang; Peter B Sampson; John F Honek; Brian W Matthews
Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
Biochemistry 1999;38(45):14810-9.
1999: Nadine C Gassner; Walter A Baase; Joel D Lindstrom; J Lu; Frederick W Dahlquist; Brian W Matthews
Methionine and alanine substitutions show that the formation of wild-type-like structure in the carboxy-terminal domain of T4 lysozyme is a rate-limiting step in folding.
Biochemistry 1999;38(44):14451-60.
1999: J W Wray; Walter A Baase; Joel D Lindstrom; Larry H Weaver; A R Poteete; Brian W Matthews
Structural analysis of a non-contiguous second-site revertant in T4 lysozyme shows that increasing the rigidity of a protein can enhance its stability.
Journal of molecular biology 1999;292(5):1111-20.
1999: RA Kovall; Brian W Matthews
Type II restriction endonucleases: structural, functional and evolutionary relationships.
Current opinion in chemical biology 1999;3(5):578-83.
1999: Ryota Kuroki; Larry H Weaver; Brian W Matthews
Structural basis of the conversion of T4 lysozyme into a transglycosidase by reengineering the active site.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):8949-54.
1999: W Todd Lowther; A M Orville; D T Madden; S Lim; D H Rich; Brian W Matthews
Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry 1999;38(24):7678-88.
1999: Martin Sagermann; Walter A Baase; Brian W Matthews
Structural characterization of an engineered tandem repeat contrasts the importance of context and sequence in protein folding.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6078-83.
1999: Douglas H Juers; Reuben E Huber; Brian W Matthews
Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between beta-galactosidase and other glycohydrolases.
Protein science : a publication of the Protein Society 1999;8(1):122-36.
1998: Ryota Kuroki; K Morimoto; Brian W Matthews
Converting T4 phage lysozyme into a transglycosidase.
Annals of the New York Academy of Sciences 1998;864():362-5.
1998: W Todd Lowther; Debra McMillen; A M Orville; Brian W Matthews
The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12153-7.
1998: RA Kovall; Brian W Matthews
Structural, functional, and evolutionary relationships between lambda-exonuclease and the type II restriction endonucleases.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):7893-7.
1998: RA Albright; Brian W Matthews
Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution.
Journal of molecular biology 1998;280(1):137-51.
1998: D H Ohlendorf; Dale E Tronrud; Brian W Matthews
Refined structure of Cro repressor protein from bacteriophage lambda suggests both flexibility and plasticity.
Journal of molecular biology 1998;280(1):129-36.
1998: RA Albright; Michael C Mossing; Brian W Matthews
Crystal structure of an engineered Cro monomer bound nonspecifically to DNA: possible implications for nonspecific binding by the wild-type protein.
Protein science : a publication of the Protein Society 1998;7(7):1485-94.
1998: P B Rupert; Gary W. Daughdrill; Bruce Bowerman; Brian W Matthews
A new DNA-binding motif in the Skn-1 binding domain-DNA complex.
Nature structural biology 1998;5(6):484-91.
1998: RA Albright; Brian W Matthews
How Cro and lambda-repressor distinguish between operators: the structural basis underlying a genetic switch.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3431-6.
1998: EP Baldwin; Walter A Baase; X j Zhang; Victoria A Feher; Brian W Matthews
Generation of ligand binding sites in T4 lysozyme by deficiency-creating substitutions.
Journal of molecular biology 1998;277(2):467-85.
1998: L A Lipscomb; Nadine C Gassner; S D Snow; A M Eldridge; Walter A Baase; D L Drew; Brian W Matthews
Context-dependent protein stabilization by methionine-to-leucine substitution shown in T4 lysozyme.
Protein science : a publication of the Protein Society 1998;7(3):765-73.
1998: J Xu; Walter A Baase; EP Baldwin; Brian W Matthews
The response of T4 lysozyme to large-to-small substitutions within the core and its relation to the hydrophobic effect.
Protein science : a publication of the Protein Society 1998;7(1):158-77.
1997: RA Kovall; Brian W Matthews
Toroidal structure of lambda-exonuclease.
Science (New York, N.Y.) 1997;277(5333):1824-7.
1997: Brian W Matthews
Picture story. Nice guys needn't finish last.
Nature structural biology 1997;4(7):518.
1996: I R Vetter; Walter A Baase; D W Heinz; J P Xiong; S Snow; Brian W Matthews
Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme.
Protein science : a publication of the Protein Society 1996;5(12):2399-415.
1996: Nadine C Gassner; Walter A Baase; Brian W Matthews
A test of the "jigsaw puzzle" model for protein folding by multiple methionine substitutions within the core of T4 lysozyme.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12155-8.
1996: E Baldwin; J Xu; O Hajiseyedjavadi; Walter A Baase; Brian W Matthews
Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme.
Journal of molecular biology 1996;259(3):542-59.
1996: R A Albright; Michael C Mossing; Brian W Matthews
High-resolution structure of an engineered Cro monomer shows changes in conformation relative to the native dimer.
Biochemistry 1996;35(3):735-42.
1996: Brian W Matthews
Structural and genetic analysis of the folding and function of T4 lysozyme.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(1):35-41.
1995: Ryota Kuroki; Larry H Weaver; Brian W Matthews
Structure-based design of a lysozyme with altered catalytic activity.
Nature structural biology 1995;2(11):1007-11.
1995: X J Zhang; Walter A Baase; Brian Shoichet; K P Wilson; Brian W Matthews
Enhancement of protein stability by the combination of point mutations in T4 lysozyme is additive.
Protein engineering 1995;8(10):1017-22.
1995: D R Holland; Andrew C Hausrath; D Juers; Brian W Matthews
Structural analysis of zinc substitutions in the active site of thermolysin.
Protein science : a publication of the Protein Society 1995;4(10):1955-65.
1995: X J Zhang; J A Wozniak; Brian W Matthews
Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
Journal of molecular biology 1995;250(4):527-52.
1995: A Morton; Brian W Matthews
Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity.
Biochemistry 1995;34(27):8576-88.
1995: A Morton; Walter A Baase; Brian W Matthews
Energetic origins of specificity of ligand binding in an interior nonpolar cavity of T4 lysozyme.
Biochemistry 1995;34(27):8564-75.
1995: M Blaber; Walter A Baase; Nadine C Gassner; Brian W Matthews
Alanine scanning mutagenesis of the alpha-helix 115-123 of phage T4 lysozyme: effects on structure, stability and the binding of solvent.
Journal of molecular biology 1995;246(2):317-30.
1995: Brian Shoichet; Walter A Baase; Ryota Kuroki; Brian W Matthews
A relationship between protein stability and protein function.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(2):452-6.
1995: Larry H Weaver; M G Grütter; Brian W Matthews
The refined structures of goose lysozyme and its complex with a bound trisaccharide show that the "goose-type" lysozymes lack a catalytic aspartate residue.
Journal of molecular biology 1995;245(1):54-68.
1995: Brian W Matthews
Studies on protein stability with T4 lysozyme.
Advances in protein chemistry 1995;46():249-78.
1994: X J Zhang; Brian W Matthews
Enhancement of the method of molecular replacement by incorporation of known structural information.
Acta crystallographica. Section D, Biological crystallography 1994;50(Pt 5):675-86.
1994: E P Baldwin; Brian W Matthews
Core-packing constraints, hydrophobicity and protein design.
Current opinion in biotechnology 1994;5(4):396-402.
1994: Andrew C Hausrath; Brian W Matthews
Redetermination and refinement of the complex of benzylsuccinic acid with thermolysin and its relation to the complex with carboxypeptidase A.
The Journal of biological chemistry 1994;269(29):18839-42.
1994: X J Zhang; Brian W Matthews
Conservation of solvent-binding sites in 10 crystal forms of T4 lysozyme.
Protein science : a publication of the Protein Society 1994;3(7):1031-9.
1994: Raymond Jacobsonr; X J Zhang; R F DuBose; Brian W Matthews
Three-dimensional structure of beta-galactosidase from E. coli.
Nature 1994;369(6483):761-6.
1994: D R Holland; L S Cousens; W Meng; Brian W Matthews
Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.
Journal of molecular biology 1994;239(3):385-400.
1994: Brian W Matthews; Charles S Craik; H Neurath
Can small cyclic peptides have the activity and specificity of proteolytic enzymes?
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4103-5.
1994: J. Fernando Bazan; Larry H Weaver; Steven L Roderick; Robert Huber; Brian W Matthews
Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2473-7.
1994: D W Heinz; Brian W Matthews
Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.
Protein engineering 1994;7(3):301-7.
1994: D W Heinz; Walter A Baase; X J Zhang; M Blaber; Frederick W Dahlquist; Brian W Matthews
Accommodation of amino acid insertions in an alpha-helix of T4 lysozyme. Structural and thermodynamic analysis.
Journal of molecular biology 1994;236(3):869-86.
1994: M Blaber; X J Zhang; J D Lindstrom; S D Pepiot; Walter A Baase; Brian W Matthews
Determination of alpha-helix propensity within the context of a folded protein. Sites 44 and 131 in bacteriophage T4 lysozyme.
Journal of molecular biology 1994;235(2):600-24.
1994: D R Holland; P L Barclay; J C Danilewicz; Brian W Matthews; K James
Inhibition of thermolysin and neutral endopeptidase 24.11 by a novel glutaramide derivative: X-ray structure determination of the thermolysin-inhibitor complex.
Biochemistry 1994;33(1):51-6.
1993: Ryota Kuroki; Larry H Weaver; Brian W Matthews
A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme.
Science (New York, N.Y.) 1993;262(5142):2030-3.
1993: E P Baldwin; O Hajiseyedjavadi; Walter A Baase; Brian W Matthews
The role of backbone flexibility in the accommodation of variants that repack the core of T4 lysozyme.
Science (New York, N.Y.) 1993;262(5140):1715-8.
1993: P Pjura; Brian W Matthews
Structures of randomly generated mutants of T4 lysozyme show that protein stability can be enhanced by relaxation of strain and by improved hydrogen bonding via bound solvent.
Protein science : a publication of the Protein Society 1993;2(12):2226-32.
1993: P Pjura; M Matsumura; Walter A Baase; Brian W Matthews
Development of an in vivo method to identify mutants of phage T4 lysozyme of enhanced thermostability.
Protein science : a publication of the Protein Society 1993;2(12):2217-25.
1993: M Blaber; J D Lindstrom; Nadine C Gassner; J Xu; D W Heinz; Brian W Matthews
Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.
Biochemistry 1993;32(42):11363-73.
1993: D E Anderson; J H Hurley; H Nicholson; Walter A Baase; Brian W Matthews
Hydrophobic core repacking and aromatic-aromatic interaction in the thermostable mutant of T4 lysozyme Ser 117-->Phe.
Protein science : a publication of the Protein Society 1993;2(8):1285-90.
1993: A E Eriksson; L S Cousens; Brian W Matthews
Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution.
Protein science : a publication of the Protein Society 1993;2(8):1274-84.
1993: M Blaber; X J Zhang; Brian W Matthews
Structural basis of amino acid alpha helix propensity.
Science (New York, N.Y.) 1993;260(5114):1637-40.
1993: Steven L Roderick; Brian W Matthews
Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme.
Biochemistry 1993;32(15):3907-12.
1993: P Pjura; Lawrence P McIntosh; J A Wozniak; Brian W Matthews
Perturbation of Trp 138 in T4 lysozyme by mutations at Gln 105 used to correlate changes in structure, stability, solvation, and spectroscopic properties.
Proteins 1993;15(4):401-12.
1993: D W Heinz; Walter A Baase; Frederick W Dahlquist; Brian W Matthews
How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme.
Nature 1993;361(6412):561-4.
1993: A E Eriksson; Walter A Baase; Brian W Matthews
Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences.
Journal of molecular biology 1993;229(3):747-69.
1992: D R Holland; Dale E Tronrud; H W Pley; K M Flaherty; W Stark; Johan N Jansonius; David B McKay; Brian W Matthews
Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.
Biochemistry 1992;31(46):11310-6.
1992: J H Hurley; D A Mason; Brian W Matthews
Flexible-geometry conformational energy maps for the amino acid residue preceding a proline.
Biopolymers 1992;32(11):1443-6.
1992: H Nicholson; Dale E Tronrud; W J Becktel; Brian W Matthews
Analysis of the effectiveness of proline substitutions and glycine replacements in increasing the stability of phage T4 lysozyme.
Biopolymers 1992;32(11):1431-41.
1992: M M Dixon; H Nicholson; L Shewchuk; Walter A Baase; Brian W Matthews
Structure of a hinge-bending bacteriophage T4 lysozyme mutant, Ile3-->Pro.
Journal of molecular biology 1992;227(3):917-33.
1992: K P Wilson; L M Shewchuk; Richard G Brennan; A J Otsuka; Brian W Matthews
Escherichia coli biotin holoenzyme synthetase/bio repressor crystal structure delineates the biotin- and DNA-binding domains.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9257-61.
1992: X J Zhang; Walter A Baase; Brian W Matthews
Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Protein science : a publication of the Protein Society 1992;1(6):761-76.
1992: K P Wilson; B A Malcolm; Brian W Matthews
Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme.
The Journal of biological chemistry 1992;267(15):10842-9.
1992: D W Heinz; Walter A Baase; Brian W Matthews
Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):3751-5.
1992: J H Hurley; Walter A Baase; Brian W Matthews
Design and structural analysis of alternative hydrophobic core packing arrangements in bacteriophage T4 lysozyme.
Journal of molecular biology 1992;224(4):1143-59.
1992: J A Bell; W J Becktel; U Sauer; Walter A Baase; Brian W Matthews
Dissection of helix capping in T4 lysozyme by structural and thermodynamic analysis of six amino acid substitutions at Thr 59.
Biochemistry 1992;31(14):3590-6.
1992: Raymond Jacobsonr; Brian W Matthews
Crystallization of beta-galactosidase from Escherichia coli.
Journal of molecular biology 1992;223(4):1177-82.
1992: U H Sauer; D P San; Brian W Matthews
Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions.
The Journal of biological chemistry 1992;267(4):2393-9.
1992: A E Eriksson; Walter A Baase; J A Wozniak; Brian W Matthews
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene.
Nature 1992;355(6358):371-3.
1992: A E Eriksson; Walter A Baase; X J Zhang; D W Heinz; M Blaber; E P Baldwin; Brian W Matthews
Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect.
Science (New York, N.Y.) 1992;255(5041):178-83.
1992: Dale E Tronrud; Steven L Roderick; Brian W Matthews
Structural basis for the action of thermolysin.
Matrix (Stuttgart, Germany). Supplement 1992;1():107-11.
1992: Raymond Jacobsonr; M Matsumura; H R Faber; Brian W Matthews
Structure of a stabilizing disulfide bridge mutant that closes the active-site cleft of T4 lysozyme.
Protein science : a publication of the Protein Society 1992;1(1):46-57.
1992: Walter A Baase; A E Eriksson; X J Zhang; D W Heinz; U Sauer; M Blaber; E P Baldwin; J A Wozniak; Brian W Matthews
Dissection of protein structure and folding by directed mutagenesis.
Faraday discussions 1992;(93):173-81.
1991: S Dao-pin; D E Anderson; Walter A Baase; Frederick W Dahlquist; Brian W Matthews
Structural and thermodynamic consequences of burying a charged residue within the hydrophobic core of T4 lysozyme.
Biochemistry 1991;30(49):11521-9.
1991: H Nicholson; D E Anderson; S Dao-pin; Brian W Matthews
Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme.
Biochemistry 1991;30(41):9816-28.
1991: S Dao-pin; E Söderlind; Walter A Baase; J A Wozniak; U Sauer; Brian W Matthews
Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability.
Journal of molecular biology 1991;221(3):873-87.
1991: S Daopin; Thomas Alber; Walter A Baase; J A Wozniak; Brian W Matthews
Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme.
Journal of molecular biology 1991;221(2):647-67.
1991: D P Sun; U Sauer; H Nicholson; Brian W Matthews
Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis.
Biochemistry 1991;30(29):7142-53.
1991: A E Eriksson; L S Cousens; Larry H Weaver; Brian W Matthews
Three-dimensional structure of human basic fibroblast growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3441-5.
1991: M M Dixon; Richard G Brennan; Brian W Matthews
Structure of gamma-chymotrypsin in the range pH 2.0 to pH 10.5 suggests that gamma-chymotrypsin is a covalent acyl-enzyme adduct at low pH.
International journal of biological macromolecules 1991;13(2):89-96.
1991: X J Zhang; Walter A Baase; Brian W Matthews
Toward a simplification of the protein folding problem: a stabilizing polyalanine alpha-helix engineered in T4 lysozyme.
Biochemistry 1991;30(8):2012-7.
1991: Anthony R Poteete; D P Sun; H Nicholson; Brian W Matthews
Second-site revertants of an inactive T4 lysozyme mutant restore activity by restructuring the active site cleft.
Biochemistry 1991;30(5):1425-32.
1991: J A Bell; K P Wilson; X J Zhang; H R Faber; H Nicholson; Brian W Matthews
Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths.
Proteins 1991;10(1):10-21.
1991: S Dao-pin; H Nicholson; Walter A Baase; X J Zhang; J A Wozniak; Brian W Matthews
Structural and genetic analysis of electrostatic and other interactions in bacteriophage T4 lysozyme.
Ciba Foundation symposium 1991;161():52-62.
1990: H R Faber; Brian W Matthews
A mutant T4 lysozyme displays five different crystal conformations.
Nature 1990;348(6298):263-6.
1990: Richard G Brennan; Steven L Roderick; Y Takeda; Brian W Matthews
Protein-DNA conformational changes in the crystal structure of a lambda Cro-operator complex.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):8165-9.
1990: B A Malcolm; K P Wilson; Brian W Matthews; Jack F Kirsch; A C Wilson
Ancestral lysozymes reconstructed, neutrality tested, and thermostability linked to hydrocarbon packing.
Nature 1990;345(6270):86-9.
1990: P E Pjura; M Matsumura; J A Wozniak; Brian W Matthews
Structure of a thermostable disulfide-bridge mutant of phage T4 lysozyme shows that an engineered cross-link in a flexible region does not increase the rigidity of the folded protein.
Biochemistry 1990;29(10):2592-8.
1990: S Dao-Pin; Walter A Baase; Brian W Matthews
A mutant T4 lysozyme (Val 131----Ala) designed to increase thermostability by the reduction of strain within an alpha-helix.
Proteins 1990;7(2):198-204.
1989: M Matsumura; G Signor; Brian W Matthews
Substantial increase of protein stability by multiple disulphide bonds.
Nature 1989;342(6247):291-3.
1989: H Nicholson; E Söderlind; Dale E Tronrud; Brian W Matthews
Contributions of left-handed helical residues to the structure and stability of bacteriophage T4 lysozyme.
Journal of molecular biology 1989;210(1):181-93.
1989: M Karpusas; Walter A Baase; M Matsumura; Brian W Matthews
Hydrophobic packing in T4 lysozyme probed by cavity-filling mutants.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(21):8237-41.
1989: M Matsumura; J A Wozniak; D P Sun; Brian W Matthews
Structural studies of mutants of T4 lysozyme that alter hydrophobic stabilization.
The Journal of biological chemistry 1989;264(27):16059-66.
1989: M Matsumura; W J Becktel; M Levitt; Brian W Matthews
Stabilization of phage T4 lysozyme by engineered disulfide bonds.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6562-6.
1989: M M Dixon; Brian W Matthews
Is gamma-chymotrypsin a tetrapeptide acyl-enzyme adduct of alpha-chymotrypsin?
Biochemistry 1989;28(17):7033-8.
1989: Larry H Weaver; T M Gray; M G Grütter; D E Anderson; J A Wozniak; Frederick W Dahlquist; Brian W Matthews
High-resolution structure of the temperature-sensitive mutant of phage lysozyme, Arg 96----His.
Biochemistry 1989;28(9):3793-7.
1989: Steven L Roderick; M C Fournie-Zaluski; B P Roques; Brian W Matthews
Thiorphan and retro-thiorphan display equivalent interactions when bound to crystalline thermolysin.
Biochemistry 1989;28(4):1493-7.
1989: M Matsumura; Brian W Matthews
Control of enzyme activity by an engineered disulfide bond.
Science (New York, N.Y.) 1989;243(4892):792-4.
1989: Richard G Brennan; Brian W Matthews
The helix-turn-helix DNA binding motif.
The Journal of biological chemistry 1989;264(4):1903-6.
1989: Richard G Brennan; S Vasu; Brian W Matthews; A J Otsuka
Crystallization of the bifunctional biotin operon repressor.
The Journal of biological chemistry 1989;264(1):5.
1988: H Nicholson; W J Becktel; Brian W Matthews
Enhanced protein thermostability from designed mutations that interact with alpha-helix dipoles.
Nature 1988;336(6200):651-6.
1988: Steven L Roderick; Brian W Matthews
Crystallization of methionine aminopeptidase from Escherichia coli.
The Journal of biological chemistry 1988;263(32):16531.
1988: S James Remington; R G Woodbury; R A Reynolds; Brian W Matthews; H Neurath
The structure of rat mast cell protease II at 1.9-A resolution.
Biochemistry 1988;27(21):8097-105.
1988: M Matsumura; W J Becktel; Brian W Matthews
Hydrophobic stabilization in T4 lysozyme determined directly by multiple substitutions of Ile 3.
Nature 1988;334(6181):406-10.
1988: H M Holden; Brian W Matthews
The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis.
The Journal of biological chemistry 1988;263(7):3256-60.
1988: Thomas Alber; J A Bell; D P Sun; H Nicholson; J A Wozniak; S Cook; Brian W Matthews
Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability.
Science (New York, N.Y.) 1988;239(4840):631-5.
1987: H M Holden; Dale E Tronrud; A F Monzingo; Larry H Weaver; Brian W Matthews
Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry 1987;26(26):8542-53.
1987: T M Gray; Brian W Matthews
Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid.
The Journal of biological chemistry 1987;262(35):16858-64.
1987: Thomas Alber; D P Sun; K Wilson; J A Wozniak; S P Cook; Brian W Matthews
Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature 1987;330(6143):41-6.
1987: Brian W Matthews
Genetic and structural analysis of the protein stability problem.
Biochemistry 1987;26(22):6885-8.
1987: Brian W Matthews; H Nicholson; W J Becktel
Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6663-7.
1987: M G Grütter; T M Gray; Larry H Weaver; T A Wilson; Brian W Matthews
Structural studies of mutants of the lysozyme of bacteriophage T4. The temperature-sensitive mutant protein Thr157----Ile.
Journal of molecular biology 1987;197(2):315-29.
1987: Thomas Alber; D P Sun; J A Nye; D C Muchmore; Brian W Matthews
Temperature-sensitive mutations of bacteriophage T4 lysozyme occur at sites with low mobility and low solvent accessibility in the folded protein.
Biochemistry 1987;26(13):3754-8.
1987: D P Sun; Thomas Alber; J A Bell; Larry H Weaver; Brian W Matthews
Use of site-directed mutagenesis to obtain isomorphous heavy-atom derivatives for protein crystallography: cysteine-containing mutants of phage T4 lysozyme.
Protein engineering 1987;1(2):115-23.
1987: Dale E Tronrud; H M Holden; Brian W Matthews
Structures of two thermolysin-inhibitor complexes that differ by a single hydrogen bond.
Science (New York, N.Y.) 1987;235(4788):571-4.
1986: Dale E Tronrud; A F Monzingo; Brian W Matthews
Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
European journal of biochemistry / FEBS 1986;157(2):261-8.
1985: R Swanson; Larry H Weaver; S J Remington; Brian W Matthews; Thomas O Baldwin
Crystals of luciferase from Vibrio harveyi. A preliminary characterization.
The Journal of biological chemistry 1985;260(2):1287-9.
1984: Larry H Weaver; M G Grütter; S J Remington; T M Gray; N W Isaacs; Brian W Matthews
Comparison of goose-type, chicken-type, and phage-type lysozymes illustrates the changes that occur in both amino acid sequence and three-dimensional structure during evolution.
Journal of molecular evolution 1984;21(2):97-111.
1983: M G Grütter; Larry H Weaver; Brian W Matthews
Goose lysozyme structure: an evolutionary link between hen and bacteriophage lysozymes?
Nature 1983;303(5920):828-31.
1981: Brian W Matthews; S J Remington; M G Grütter; W F Anderson
Relation between hen egg white lysozyme and bacteriophage T4 lysozyme: evolutionary implications.
Journal of molecular biology 1981;147(4):545-58.
1981: W F Anderson; M G Grütter; S J Remington; Larry H Weaver; Brian W Matthews
Crystallographic determination of the mode of binding of oligosaccharides to T4 bacteriophage lysozyme: implications for the mechanism of catalysis.
Journal of molecular biology 1981;147(4):523-43.
1981: Brian W Matthews; M G Grütter; W F Anderson; S J Remington
Common precursor of lysozymes of hen egg-white and bacteriophage T4.
Nature 1981;290(5804):334-5.
1972: Brian W Matthews; P M Colman; Johan N Jansonius; K Titani; K A Walsh; H Neurath
Structure of thermolysin.
Nature: New biology 1972;238(80):41-3.
1972: Brian W Matthews; Johan N Jansonius; P M Colman; B P Schoenborn; D Dupourque
Three-dimensional structure of thermolysin.
Nature: New biology 1972;238(80):37-41.