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Kathleen Matthews

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Chemicals & Drugs

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Escherichia coli

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TOP 3
Daniel J Catanese; Kathleen S Matthews
Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT.
Jia Xu; Mingzhi Chen; Shirley Liu; Jianpeng Ma; Kathleen S Matthews
Altering residues N125 and D149 impacts sugar effector binding and allosteric parameters in Escherichia coli lactose repressor.
Jia Xu; Kai-Wei Liu; Kathleen S Matthews; Sibani L Biswal
Monitoring DNA binding to Escherichia coli lactose repressor using quartz crystal microbalance with dissipation.

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All Publications

2011: Daniel J Catanese; Kathleen S Matthews
Disconnected Interacting Protein 1 binds with high affinity to pre-tRNA and ADAT.
Biochemical and biophysical research communications 2011;414(3):506-11.
2011: Jia Xu; Mingzhi Chen; Shirley Liu; Jianpeng Ma; Kathleen S Matthews
Altering residues N125 and D149 impacts sugar effector binding and allosteric parameters in Escherichia coli lactose repressor.
Biochemistry 2011;50(42):9002-13.
2011: Jia Xu; Kai-Wei Liu; Kathleen S Matthews; Sibani L Biswal
Monitoring DNA binding to Escherichia coli lactose repressor using quartz crystal microbalance with dissipation.
Langmuir : the ACS journal of surfaces and colloids 2011;27(8):4900-5.
2011: Ying Liu; Kathleen S Matthews; Zabeena Merchant; Kim L Gonzalez; Hao-Ching Hsiao; Sarah E Bondos
Media composition influences yeast one- and two-hybrid results.
Biological procedures online 2011;13():6.
2010: Zhao Huang; Yang Lu; Ravish Majithia; Jaimin Shah; Kenith Meissner; Kathleen S Matthews; Sarah E Bondos; Jun Lou
Size dictates mechanical properties for protein fibers self-assembled by the Drosophila hox transcription factor ultrabithorax.
Biomacromolecules 2010;11(12):3644-51.
2010: Hongli Zhan; Maricela Camargo; Kathleen S Matthews
Positions 94-98 of the lactose repressor N-subdomain monomer-monomer interface are critical for allosteric communication.
Biochemistry 2010;49(39):8636-45.
2010: Daniel J Catanese; Kathleen S Matthews
High affinity, dsRNA binding by disconnected interacting protein 1.
Biochemical and biophysical research communications 2010;399(2):186-91.
2009: Ying Liu; Kathleen S Matthews; Sarah E Bondos
Internal regulatory interactions determine DNA binding specificity by a Hox transcription factor.
Journal of molecular biology 2009;390(4):760-74.
2009: Jia Xu; Kathleen S Matthews
Flexibility in the inducer binding region is crucial for allostery in the Escherichia coli lactose repressor.
Biochemistry 2009;48(22):4988-98.
2009: Alexandra M Greer; Zhao Huang; Ashley Oriakhi; Yang Lu; Jun Lou; Kathleen S Matthews; Sarah E Bondos
The Drosophila transcription factor ultrabithorax self-assembles into protein-based biomaterials with multiple morphologies.
Biomacromolecules 2009;10(4):829-37.
2009: Liskin Swint-Kruse; Kathleen S Matthews
Allostery in the LacI/GalR family: variations on a theme.
Current opinion in microbiology 2009;12(2):129-37.
2009: Hongli Zhan; Zhifei Sun; Kathleen S Matthews
Functional impact of polar and acidic substitutions in the lactose repressor hydrophobic monomer.monomer interface with a buried lysine.
Biochemistry 2009;48(6):1305-14.
2008: Ying Liu; Kathleen S Matthews; Sarah E Bondos
Multiple intrinsically disordered sequences alter DNA binding by the homeodomain of the Drosophila hox protein ultrabithorax.
The Journal of biological chemistry 2008;283(30):20874-87.
2008: Marc Taraban; Hongli Zhan; Andrew E Whitten; David B Langley; Kathleen S Matthews; Liskin Swint-Kruse; Jill Trewhella
Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein.
Journal of molecular biology 2008;376(2):466-81.
2007: Corey J Wilson; Hongli Zhan; Liskin Swint-Kruse; Kathleen S Matthews
Ligand interactions with lactose repressor protein and the repressor-operator complex: the effects of ionization and oligomerization on binding.
Biophysical chemistry 2007;126(1-3):94-105.
2007: Corey J Wilson; Hongli Zhan; Liskin Swint-Kruse; Kathleen S Matthews
The lactose repressor system: paradigms for regulation, allosteric behavior and protein folding.
Cellular and molecular life sciences : CMLS 2007;64(1):3-16.
2006: Michelle K Calabretta; Kathleen S Matthews; Vicki L Colvin
DNA binding to protein-gold nanocrystal conjugates.
Bioconjugate chemistry 2006;17(5):1156-61.
2006: Hongli Zhan; Liskin Swint-Kruse; Kathleen S Matthews
Extrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix.
Biochemistry 2006;45(18):5896-906.
2006: Sarah E Bondos; Xin-Xing Tan; Kathleen S Matthews
Physical and genetic interactions link hox function with diverse transcription factors and cell signaling proteins.
Molecular & cellular proteomics : MCP 2006;5(5):824-34.
2005: Corey J Wilson; Payel Das; Cecilia Clementi; Kathleen S Matthews; Pernilla Wittung-Stafshede
The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14563-8.
2005: Payel Das; Corey J Wilson; Giovanni Fossati; Pernilla Wittung-Stafshede; Kathleen S Matthews; Cecilia Clementi
Characterization of the folding landscape of monomeric lactose repressor: quantitative comparison of theory and experiment.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14569-74.
2005: Liskin Swint-Kruse; Hongli Zhan; Kathleen S Matthews
Integrated insights from simulation, experiment, and mutational analysis yield new details of LacI function.
Biochemistry 2005;44(33):11201-13.
2005: Michelle Calabretta; Jennifer A Jamison; Joshua C Falkner; Yunping Liu; Benjamin D Yuhas; Kathleen S Matthews; Vicki L Colvin
Analytical ultracentrifugation for characterizing nanocrystals and their bioconjugates.
Nano letters 2005;5(5):963-7.
2004: Sarah E Bondos; Daniel J Catanese; Xin-Xing Tan; Alicia Bicknell; Likun Li; Kathleen S Matthews
Hox transcription factor ultrabithorax Ib physically and genetically interacts with disconnected interacting protein 1, a double-stranded RNA-binding protein.
The Journal of biological chemistry 2004;279(25):26433-44.
2004: Liskin Swint-Kruse; Kathleen S Matthews
Thermodynamics, protein modification, and molecular dynamics in characterizing lactose repressor protein: strategies for complex analyses of protein structure-function.
Methods in enzymology 2004;379():188-209.
2003: Liskin Swint-Kruse; Hongli Zhan; Bonnie M Fairbanks; Atul Maheshwari; Kathleen S Matthews
Perturbation from a distance: mutations that alter LacI function through long-range effects.
Biochemistry 2003;42(47):14004-16.
2003: Terence C Flynn; Liskin Swint-Kruse; Yifei Kong; Christopher Booth; Kathleen S Matthews; Jianpeng Ma
Allosteric transition pathways in the lactose repressor protein core domains: asymmetric motions in a homodimer.
Protein science : a publication of the Protein Society 2003;12(11):2523-41.
2002: Liskin Swint-Kruse; Christopher Larson; B Montgomery Pettitt; Kathleen S Matthews
Fine-tuning function: correlation of hinge domain interactions with functional distinctions between LacI and PurR.
Protein science : a publication of the Protein Society 2002;11(4):778-94.
2002: Xin-Xing Tan; Sarah E Bondos; Likun Li; Kathleen S Matthews
Transcription activation by ultrabithorax Ib protein requires a predicted alpha-helical region.
Biochemistry 2002;41(8):2774-85.
2002: Nicole Magnasco Nichols; Kathleen S Matthews
Human p53 phosphorylation mimic, S392E, increases nonspecific DNA affinity and thermal stability.
Biochemistry 2002;41(1):170-8.
2001: CM Falcon; Kathleen S Matthews
Engineered disulfide linking the hinge regions within lactose repressor dimer increases operator affinity, decreases sequence selectivity, and alters allostery.
Biochemistry 2001;40(51):15650-9.
2001: Nicole Magnasco Nichols; Kathleen S Matthews
p53 unfolding detected by CD but not by tryptophan fluorescence.
Biochemical and biophysical research communications 2001;288(1):111-5.
2001: M I Moraitis; H Xu; Kathleen S Matthews
Ion concentration and temperature dependence of DNA binding: comparison of PurR and LacI repressor proteins.
Biochemistry 2001;40(27):8109-17.
2001: Nicole Magnasco Nichols; Kathleen S Matthews
Protein-DNA binding correlates with structural thermostability for the full-length human p53 protein.
Biochemistry 2001;40(13):3847-58.
2000: CM Falcon; Kathleen S Matthews
Operator DNA sequence variation enhances high affinity binding by hinge helix mutants of lactose repressor protein.
Biochemistry 2000;39(36):11074-83.
2000: Kathleen S Matthews; CM Falcon; Liskin Swint-Kruse
Relieving repression.
Nature structural biology 2000;7(3):184-7.
2000: D R Wycuff; Kathleen S Matthews
Generation of an AraC-araBAD promoter-regulated T7 expression system.
Analytical biochemistry 2000;277(1):67-73.
1999: CM Falcon; Kathleen S Matthews
Glycine insertion in the hinge region of lactose repressor protein alters DNA binding.
The Journal of biological chemistry 1999;274(43):30849-57.
1999: Andrew Ozarowski; JK Barry; Kathleen S Matthews; August H Maki
Ligand-induced conformational changes in lactose repressor: a phosphorescence and ODMR study of single-tryptophan mutants.
Biochemistry 1999;38(21):6715-22.
1999: JK Barry; Kathleen S Matthews
Thermodynamic analysis of unfolding and dissociation in lactose repressor protein.
Biochemistry 1999;38(20):6520-8.
1999: JK Barry; Kathleen S Matthews
Substitutions at histidine 74 and aspartate 278 alter ligand binding and allostery in lactose repressor protein.
Biochemistry 1999;38(12):3579-90.
1998: H Xu; M Moraitis; R J Reedstrom; Kathleen S Matthews
Kinetic and thermodynamic studies of purine repressor binding to corepressor and operator DNA.
The Journal of biological chemistry 1998;273(15):8958-64.
1998: Liskin Swint-Kruse; Kathleen S Matthews; PE Smith; B Montgomery Pettitt
Comparison of simulated and experimentally determined dynamics for a variant of the Lacl DNA-binding domain, Nlac-P.
Biophysical journal 1998;74(1):413-21.
1998: Kathleen S Matthews; J C Nichols
Lactose repressor protein: functional properties and structure.
Progress in nucleic acid research and molecular biology 1998;58():127-64.
1997: JK Barry; Kathleen S Matthews
Ligand-induced conformational changes in lactose repressor: a fluorescence study of single tryptophan mutants.
Biochemistry 1997;36(50):15632-42.
1997: CM Falcon; Liskin Swint-Kruse; Kathleen S Matthews
Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage.
The Journal of biological chemistry 1997;272(43):26818-21.
1997: J C Nichols; Kathleen S Matthews
Combinatorial mutations of lac repressor. Stability of monomer-monomer interface is increased by apolar substitution at position 84.
The Journal of biological chemistry 1997;272(30):18550-7.
1997: Likun Li; Kathleen S Matthews
Differences in water release with DNA binding by ultrabithorax and deformed homeodomains.
Biochemistry 1997;36(23):7003-11.
1996: L Li; Doris P Von Kessler; P A Beachy; Kathleen S Matthews
pH-dependent enhancement of DNA binding by the ultrabithorax homeodomain.
Biochemistry 1996;35(30):9832-9.
1996: Kathleen S Matthews
The whole lactose repressor.
Science (New York, N.Y.) 1996;271(5253):1245-6.
1995: W I Chang; Kathleen S Matthews
Role of Asp274 in lac repressor: diminished sugar binding and altered conformational effects in mutants.
Biochemistry 1995;34(28):9227-34.
1995: L Li; Kathleen S Matthews
Characterization of mutants affecting the KRK sequence in the carboxyl-terminal domain of lac repressor.
The Journal of biological chemistry 1995;270(18):10640-9.
1994: J Chen; Kathleen S Matthews
Subunit dissociation affects DNA binding in a dimeric lac repressor produced by C-terminal deletion.
Biochemistry 1994;33(29):8728-35.
1994: J Chen; S Alberti; Kathleen S Matthews
Wild-type operator binding and altered cooperativity for inducer binding of lac repressor dimer mutant R3.
The Journal of biological chemistry 1994;269(17):12482-7.
1994: W I Chang; P Barrera; Kathleen S Matthews
Identification and characterization of aspartate residues that play key roles in the allosteric regulation of a transcription factor: aspartate 274 is essential for inducer binding in lac repressor.
Biochemistry 1994;33(12):3607-16.
1994: J Chen; R Surendran; J C Lee; Kathleen S Matthews
Construction of a dimeric repressor: dissection of subunit interfaces in Lac repressor.
Biochemistry 1994;33(5):1234-41.
1994: Y C Liu; Kathleen S Matthews
trp repressor mutations alter DNA complex stoichiometry.
The Journal of biological chemistry 1994;269(3):1692-8.
1993: L E Burns; A H Maki; R Spotts; Kathleen S Matthews
Characterization of the two tryptophan residues of the lactose repressor from Escherichia coli by phosphorescence and optical detection of magnetic resonance.
Biochemistry 1993;32(47):12821-9.
1993: Y C Liu; Kathleen S Matthews
Dependence of trp repressor-operator affinity, stoichiometry, and apparent cooperativity on DNA sequence and size.
The Journal of biological chemistry 1993;268(31):23239-49.
1993: Y C Liu; Kathleen S Matthews
Trp repressor interaction with bromodeoxyuridine-substituted operators alters UV-induced perturbation pattern in a sequence-dependent manner.
Biochemistry 1993;32(40):10532-42.
1993: W I Chang; John S Olson; Kathleen S Matthews
Lysine 84 is at the subunit interface of lac repressor protein.
The Journal of biological chemistry 1993;268(23):17613-22.
1993: J C Nichols; N K Vyas; Florante A Quiocho; Kathleen S Matthews
Model of lactose repressor core based on alignment with sugar-binding proteins is concordant with genetic and chemical data.
The Journal of biological chemistry 1993;268(23):17602-12.
1992: J Chen; Kathleen S Matthews
Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation.
The Journal of biological chemistry 1992;267(20):13843-50.
1992: A E Chakerian; Kathleen S Matthews
Effect of lac repressor oligomerization on regulatory outcome.
Molecular microbiology 1992;6(8):963-8.
1991: R O Spotts; A E Chakerian; Kathleen S Matthews
Arginine 197 of lac repressor contributes significant energy to inducer binding. Confirmation of homology to periplasmic sugar binding proteins.
The Journal of biological chemistry 1991;266(34):22998-3002.
1991: A E Chakerian; Kathleen S Matthews
Characterization of mutations in oligomerization domain of Lac repressor protein.
The Journal of biological chemistry 1991;266(33):22206-14.
1991: T D Allen; K L Wick; Kathleen S Matthews
Identification of amino acids in lac repressor protein cross-linked to operator DNA specifically substituted with bromodeoxyuridine.
The Journal of biological chemistry 1991;266(10):6113-9.
1991: K L Wick; Kathleen S Matthews
Interactions between lac repressor protein and site-specific bromodeoxyuridine-substituted operator DNA. Ultraviolet footprinting and protein-DNA cross-link formation.
The Journal of biological chemistry 1991;266(10):6106-12.
1991: J A Gardner; Kathleen S Matthews
Energy transfer in lactose repressor protein modified with N-[[(iodoacetyl)amino]ethyl]-5-naphthylamine-1-sulfonate.
Biochemistry 1991;30(10):2707-12.
1991: A E Chakerian; V M Tesmer; S P Manly; J K Brackett; M J Lynch; J T Hoh; Kathleen S Matthews
Evidence for leucine zipper motif in lactose repressor protein.
The Journal of biological chemistry 1991;266(3):1371-4.
1991: Kathleen S Matthews; A E Chakerian; J A Gardner
Protein chemical modification as probe of structure-function relationships.
Methods in enzymology 1991;208():468-96.
1990: J A Gardner; Kathleen S Matthews
Characterization of two mutant lactose repressor proteins containing single tryptophans.
The Journal of biological chemistry 1990;265(34):21061-7.
1990: C A Royer; J A Gardner; J M Beechem; Jean-Claude Brochon; Kathleen S Matthews
Resolution of the fluorescence decay of the two tryptophan residues of lac repressor using single tryptophan mutants.
Biophysical journal 1990;58(2):363-78.
1990: C A Royer; A E Chakerian; Kathleen S Matthews
Macromolecular binding equilibria in the lac repressor system: studies using high-pressure fluorescence spectroscopy.
Biochemistry 1990;29(20):4959-66.
1990: J J He; Kathleen S Matthews
Effect of amino acid alterations in the tryptophan-binding site of the trp repressor.
The Journal of biological chemistry 1990;265(2):731-7.
1989: W Y Chou; C Bieber; Kathleen S Matthews
Tryptophan and 8-anilino-1-naphthalenesulfonate compete for binding to trp repressor.
The Journal of biological chemistry 1989;264(31):18309-13.
1989: W Y Chou; Kathleen S Matthews
Serine to cysteine mutations in trp repressor protein alter tryptophan and operator binding.
The Journal of biological chemistry 1989;264(31):18314-9.
1989: W Y Chou; Kathleen S Matthews
Mutation in hinge region of lactose repressor protein alters physical and functional properties.
The Journal of biological chemistry 1989;264(11):6171-6.
1988: Clarence F Sams; Kathleen S Matthews
Diethyl pyrocarbonate reaction with the lactose repressor protein affects both inducer and DNA binding.
Biochemistry 1988;27(7):2277-81.
1988: A E Chakerian; Kathleen S Matthews
Regulation of the lactose repressor.
The International journal of biochemistry 1988;20(5):493-8.
1987: A E Chakerian; John S Olson; Kathleen S Matthews
Thermodynamic analysis of inducer binding to the lactose repressor protein: contributions of galactosyl hydroxyl groups and beta substituents.
Biochemistry 1987;26(23):7250-5.
1987: J A Gardner; Kathleen S Matthews
Mapping and analysis of protein sulfhydryl groups by modification with 2-bromoacetamido-4-nitrophenol.
Analytical biochemistry 1987;167(1):140-4.
1987: Peggy A Whitson; W T Hsieh; Robert D Wells; Kathleen S Matthews
Influence of supercoiling and sequence context on operator DNA binding with lac repressor.
The Journal of biological chemistry 1987;262(30):14592-9.
1987: W T Hsieh; Peggy A Whitson; Kathleen S Matthews; Robert D Wells
Influence of sequence and distance between two operators on interaction with the lac repressor.
The Journal of biological chemistry 1987;262(30):14583-91.
1987: Peggy A Whitson; Kathleen S Matthews
Chemical modification of arginine residues in the lactose repressor.
Biochemistry 1987;26(20):6502-7.
1987: Peggy A Whitson; W T Hsieh; Robert D Wells; Kathleen S Matthews
Supercoiling facilitates lac operator-repressor-pseudooperator interactions.
The Journal of biological chemistry 1987;262(11):4943-6.
1986: Peggy A Whitson; J S Olson; Kathleen S Matthews
Thermodynamic analysis of the lactose repressor-operator DNA interaction.
Biochemistry 1986;25(13):3852-8.
1986: Peggy A Whitson; Kathleen S Matthews
Dissociation of the lactose repressor-operator DNA complex: effects of size and sequence context of operator-containing DNA.
Biochemistry 1986;25(13):3845-52.
1985: S P Manly; Kathleen S Matthews; Julian M Sturtevant
Thermal denaturation of the core protein of lac repressor.
Biochemistry 1985;24(15):3842-6.
1985: W T Hsieh; Kathleen S Matthews
Lactose repressor protein modified with dansyl chloride: activity effects and fluorescence properties.
Biochemistry 1985;24(12):3043-9.
1985: A E Chakerian; M Pfahl; John S Olson; Kathleen S Matthews
A mutant lactose repressor with altered inducer and operator binding parameters.
Journal of molecular biology 1985;183(1):43-51.
1985: Clarence F Sams; V B Hemelt; F D Pinkerton; G J Schroepfer; Kathleen S Matthews
Exposure of antigenic sites during immunization. Monoclonal antibodies to monomer of lactose repressor protein.
The Journal of biological chemistry 1985;260(2):1185-90.
1984: Peggy A Whitson; A A Burgum; Kathleen S Matthews
Trinitrobenzenesulfonate modification of the lysine residues in lactose repressor protein.
Biochemistry 1984;23(25):6046-52.
1984: S P Manly; george bennett; Kathleen S Matthews
Enzymatic digestion of operator DNA in the presence of the lac repressor tryptic core.
Journal of molecular biology 1984;179(3):335-50.
1984: S P Manly; Kathleen S Matthews
lac operator DNA modification in the presence of proteolytic fragments of the repressor protein.
Journal of molecular biology 1984;179(3):315-33.
1984: Clarence F Sams; N K Vyas; F A Quiocho; Kathleen S Matthews
Predicted structure of the sugar-binding site of the lac repressor.
Nature 1984;310(5976):429-30.
1984: Clarence F Sams; Kathleen S Matthews
Chemical modification of dopamine beta-hydroxylase.
Biochimica et biophysica acta 1984;787(1):61-70.
1983: S P Manly; george bennett; Kathleen S Matthews
Perturbation of lac operator DNA modification by tryptic core protein from lac repressor.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(20):6219-23.
1981: W T Hsieh; Kathleen S Matthews
Tetranitromethane modification of the tyrosine residues of the lactose repressor.
The Journal of biological chemistry 1981;256(10):4856-62.
1981: R B O'Gorman; L Ferguson; Joan L Betz; J R Sadler; Kathleen S Matthews
Determination of the ligand-binding characteristics of several tight-binding mutants of the lactose repressor protein.
Biochimica et biophysica acta 1981;653(2):236-47.
1980: M Dunaway; S P Manly; Kathleen S Matthews
Model for lactose repressor protein and its interaction with ligands.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(12):7181-5.
1980: M Dunaway; Kathleen S Matthews
Hybrid tetramers of native and core lactose repressor protein. Assessment of operator and nonspecific DNA binding parameters and their relationship.
The Journal of biological chemistry 1980;255(21):10120-7.
1980: M Dunaway; J S Olson; J M Rosenberg; O B Kallai; R E Dickerson; Kathleen S Matthews
Kinetic studies of inducer binding to lac repressor.operator complex.
The Journal of biological chemistry 1980;255(21):10115-9.
1980: R B O'Gorman; J M Rosenberg; O B Kallai; R E Dickerson; K Itakura; A D Riggs; Kathleen S Matthews
Equilibrium binding of inducer to lac repressor.operator DNA complex.
The Journal of biological chemistry 1980;255(21):10107-14.
1980: R B O'Gorman; M Dunaway; Kathleen S Matthews
DNA binding characteristics of lactose repressor and the trypsin-resistant core repressor.
The Journal of biological chemistry 1980;255(21):10100-6.