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Mark Mattson

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Peter Sykora; Takashi Tadokoro; Jingyan Tian; Lior Weissman; David M Wilson; Jenq-Lin Yang; Leslie K Ferrarelli; Guido Keijzers; Avanti Kulkarni; Mark P Mattson; Vilhelm A Bohr
Modulation of DNA base excision repair during neuronal differentiation.
Zhi Y Guo; Cheng Z Li; Xiao J Li; Mark P Mattson; Ya L Wang; Cheng B Lu
The developmental regulation of glutamate receptor-mediated calcium signaling in primary cultured rat hippocampal neurons.
S M Rothman; Mark P Mattson
Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan.

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All Publications

2013: Peter Sykora; Takashi Tadokoro; Jingyan Tian; Lior Weissman; David M Wilson; Jenq-Lin Yang; Leslie K Ferrarelli; Guido Keijzers; Avanti Kulkarni; Mark P Mattson; Vilhelm A Bohr
Modulation of DNA base excision repair during neuronal differentiation.
Neurobiology of aging 2013;34(7):1717-27.
2013: Zhi Y Guo; Cheng Z Li; Xiao J Li; Mark P Mattson; Ya L Wang; Cheng B Lu
The developmental regulation of glutamate receptor-mediated calcium signaling in primary cultured rat hippocampal neurons.
Neuroreport 2013;24(9):492-7.
2013: S M Rothman; Mark P Mattson
Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan.
Neuroscience 2013;239():228-40.
2013: Yoshihiro Kashiwaya; M Todd King; Jong-Hwan Lee; Mark P Mattson; Mohamed R Mughal; Eitan Okun; Christian Bergman; Kieran Clarke; Ruiqian Wan; Richard L Veech
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.
Neurobiology of aging 2013;34(6):1530-9.
2013: Dong Liu; Michael Pitta; Guofeng Zhang; Xinzhi Chen; Haiyang Jiang; Elisa Mitiko Kawamoto; Jong-Hwan Lee; Mark P Mattson
Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession.
Neurobiology of aging 2013;34(6):1564-80.
2013: Jeong Seon Yoon; Mohamed R Mughal; David Tweedie; Srinivasulu Chigurupati; Nigel H Greig; Jong-Hwan Lee; Mark P Mattson
3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation.
Journal of neuroscience research 2013;91(5):671-80.
2013: Tae Gen Son; Qian-Sheng Yu; Nigel H Greig; Elisa M Kawamoto; Mark P Mattson; Simonetta Camandola
Naphthazarin protects against glutamate-induced neuronal death via activation of the Nrf2/ARE pathway.
Biochemical and biophysical research communications 2013;433(4):602-6.
2013: Sung-Chun Tang; Yu-Chi Wang; Wei-Shiung Yang; Thiruma V Arumugam; Hung-Yi Chiou; Yu-Hsuan Hsieh; Chaur-Jong Hu; Yi-Shuian Huang; Yu-I Li; Hsiao-Ching Lin; Silvia Manzanero; Mark P Mattson; Simon Phipps; Jiann-Shing Jeng
Functional role of soluble receptor for advanced glycation end products in stroke.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):585-94.
2013: Srinivasulu Chigurupati; Soumen Das; Amit Kumar; Michael McCaffery; Mohamed R Mughal; Eitan Okun; Sudipta Seal; Mark P Mattson
Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing.
Biomaterials 2013;34(9):2194-201.
2013: Kathleen J Griffioen; Emmette Hutchison; Bruce Ladenheim; Eitan Okun; Sarah M Rothman; Neil Vranis; Ruiqian Wan; Jean Lud Cadet; Mark P Mattson
Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein.
Neurobiology of aging 2013;34(3):928-35.
2013: Ronald S Petralia; Ya-Xian Wang; Fangbai Wu; Ittai Bushlin; Fred E Indig; Mark P Mattson; Pamela J Yao
Reduction of AP180 and CALM produces defects in synaptic vesicle size and density.
Neuromolecular medicine 2013;15(1):49-60.
2013: Kuti Baruch; Tamara Berkutzki; Liora Cahalon; Michal Cardon; Aleksandra Deczkowska; Nir Friedman; Hilah Gal; Fernando Gomez-Pinilla; Mark P Mattson; Nataly Mirlas-Neisberg; Wilfred Ndifon; Noga Ron-Harel; Eric Shifrut; Ilan Vaknin; Michal Schwartz
CNS-specific immunity at the choroid plexus shifts toward destructive Th2 inflammation in brain aging.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(6):2264-9.
2013: Mark Wilson; Mark P Mattson; Sige Zou
Invertebrates as workhorses for aging and intervention studies.
Ageing research reviews 2013;12(1):402-3.
2013: Sang-Ho Choi; Yasuji Matsuoka; Mark P Mattson; Takako Niikura; Raymond Scott Turner; S Sakura Minami; Saba Aid; Luca Caracciolo; Francesca Bosetti
Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.
Journal of neurochemistry 2013;124(1):59-68.
2013: Dimitrios Kapogiannis; David A Reiter; Auriel A Willette; Mark P Mattson
Posteromedial cortex glutamate and GABA predict intrinsic functional connectivity of the default mode network.
NeuroImage 2013;64():112-9.
2013: Elisa Mitiko Kawamoto; Mark P Mattson; C Scavone; Simonetta Camandola
Curcumin requires tumor necrosis factor α signaling to alleviate cognitive impairment elicited by lipopolysaccharide.
Neuro-Signals 2013;21(1-2):75-88.
2012: Hee Ra Park; Byung Pal Yu; Kyoung Hye Kong; Mark P Mattson; Jaewon Lee
Resveratrol inhibits the proliferation of neural progenitor cells and hippocampal neurogenesis.
The Journal of biological chemistry 2012;287(51):42588-600.
2012: Mark P Mattson
Energy intake and exercise as determinants of brain health and vulnerability to injury and disease.
Cell metabolism 2012;16(6):706-22.
2012: Ronald S Petralia; Ya-Xian Wang; Mark P Mattson; Pamela J Yao
Subcellular distribution of patched and smoothened in the cerebellar neurons.
Cerebellum (London, England) 2012;11(4):972-81.
2012: Yan Hou; Mark P Mattson; Xin Ouyang; Ruiqian Wan; Heping Cheng; Aiwu Cheng
Mitochondrial superoxide production negatively regulates neural progenitor proliferation and cerebral cortical development.
Stem cells (Dayton, Ohio) 2012;30(11):2535-47.
2012: Jing Jin; Mark P Mattson; Qi Peng; William Wood; Yongqing Zhang; Kevin G Becker; Yong Cheng; Emmette Hutchison; WENZHEN DUAN
Interrogation of brain miRNA and mRNA expression profiles reveals a molecular regulatory network that is perturbed by mutant huntingtin.
Journal of neurochemistry 2012;123(4):477-90.
2012: Guang Qiu; Kwok-Fai So; Edward L Spangler; Ruiqian Wan; Sige Zou; Rafael de Cabo; Mark P Mattson; Marshall Miller; Donald K Ingram
Neuroprotection provided by dietary restriction in rats is further enhanced by reducing glucocortocoids.
Neurobiology of aging 2012;33(10):2398-410.
2012: Nicholas Mitchell; Ronald S Petralia; Ya-Xian Wang; Duane G Currier; Alvin Kim; Mark P Mattson; Pamela J Yao
Sonic hedgehog regulates presynaptic terminal size, ultrastructure and function in hippocampal neurons.
Journal of cell science 2012;125(Pt 18):4207-13.
2012: Chandrika Canugovi; Deborah L Croteau; Neil H Feldman; Mark P Mattson; Jeong Seon Yoon; Vilhelm A Bohr
Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(37):14948-53.
2012: Sarah M Rothman; Mark P Mattson
Sleep disturbances in Alzheimer's and Parkinson's diseases.
Neuromolecular medicine 2012;14(3):194-204.
2012: Sarah M Rothman; Ruiqian Wan; Kathleen J Griffioen; Mark P Mattson
Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health.
Annals of the New York Academy of Sciences 2012;1264(1):49-63.
2012: A-Ryeong Gwon; Dong-Hoon Hyun; Thiruma V Arumugam; Sang-Ha Baik; Michel Bernier; Sic L Chan; Aiwu Cheng; Yuri Choi; Charles E Dann; Saerom Kim; Seol-Hee Kim; Yong-Kook Kwon; Jaewon Lee; William R Markesbery; Mark P Mattson; Jong-Sung Park; Sung-Chun Tang; Sunghee Yang; Young-Kwang Yun; Dong-Gyu Jo
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.
Aging cell 2012;11(4):559-68.
2012: Mark P Mattson
An ECSIT-centric view of Alzheimer's disease.
BioEssays : news and reviews in molecular, cellular and developmental biology 2012;34(7):526-7.
2012: Catherine M Schwartz; Tahereh Tavakoli; Pamela J Yao; Ernest Arenas; Katsuhiko Itoh; Charmaine Jamias; Wu Ma; Bronwen Martin; Stuart Maudsley; Sung-Soo Park; Terry M Phillips; Mahendra S Rao; Mark P Mattson
Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.
Journal of neuroscience research 2012;90(7):1367-81.
2012: Mark P Mattson
Evolutionary aspects of human exercise--born to run purposefully.
Ageing research reviews 2012;11(3):347-52.
2012: Kathleen J Griffioen; Tashalee R Brown; Simonetta Camandola; Mohamed R Mughal; Eitan Okun; Terry M Phillips; Ruiqian Wan; Mark P Mattson
Aberrant heart rate and brainstem brain-derived neurotrophic factor (BDNF) signaling in a mouse model of Huntington's disease.
Neurobiology of aging 2012;33(7):1481.e1-5.
2012: Mark P Mattson
Parkinson's disease: don't mess with calcium.
The Journal of clinical investigation 2012;122(4):1195-8.
2012: Sarah M Rothman; Sarah J Texel; Mohamed R Mughal; Simonetta Camandola; Wei-Na Cong; Nathan Herdener; Bronwen Martin; Mark P Mattson
3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress.
Neurobiology of aging 2012;33(4):830.e1-12.
2012: Dong-Hoon Hyun; Jiyeong Kim; Chang-Jin Lim; Rafael de Cabo; Chanil Moon; Mark P Mattson
The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stress.
Age (Dordrecht, Netherlands) 2012;34(2):359-70.
2012: Wei Qiang; Yongquan Luo; Mark P Mattson; Wai-Ming Yau; Robert Tycko
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(12):4443-8.
2012: Alexis M Stranahan; Mark P Mattson
Recruiting adaptive cellular stress responses for successful brain ageing.
Nature reviews. Neuroscience 2012;13(3):209-16.
2012: Cherine Belal; Spencer Bezalel; Aziz M Al'Khafaji; Neema J Ameli; Adam El Kommos; George A Kyriazis; Mark P Mattson; Mohamed R Mughal; Björn Tyrberg; Sic L Chan
The homocysteine-inducible endoplasmic reticulum (ER) stress protein Herp counteracts mutant α-synuclein-induced ER stress via the homeostatic regulation of ER-resident calcium release channel proteins.
Human molecular genetics 2012;21(5):963-77.
2012: Purevdorj B Olkhanud; Sarah Rothman; Koichi Ayukawa; Monica Bodogai; Srinivasulu Chigurupati; Neil Feldman; Jong-Hwan Lee; Enkhzol Malchinkhuu; Mark P Mattson; Mohammed Mughal; Kunio Nagashima; Eitan Okun; Arya Biragyn
DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease.
Vaccine 2012;30(9):1650-8.
2012: Aiwu Cheng; Naomi Kamimura; Yongquan Luo; Eitan Okun; Xin Ouyang; Tae Gen Son; Ruiqian Wan; Jenq-Lin Yang; Mark P Mattson
Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines.
Nature communications 2012;3():1250.
2012: Eitan Okun; Mario A Pita; Nicholas Roberts; Sarah M Rothman; Ravit Saada-Madar; Alexis M Stranahan; Thiruma V Arumugam; Boaz Barak; Kamilah Castro; Kathleen J Griffioen; Mohamed R Mughal; Mark P Mattson
Evidence for a developmental role for TLR4 in learning and memory.
PloS one 2012;7(10):e47522.
2012: Ira Driscoll; Luigi Ferrucci; Bronwen Martin; Mark P Mattson; Stuart Maudsley; Yang An; Susan M Resnick
Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults.
PloS one 2012;7(4):e35217.
2012: Demian Obregon; Md Shahaduzzaman; Jun Tian; Yuyuan Zhu; Donna Darlington; Juan Deng; Brian Giunta; Huayan Hou; Mark P Mattson; Takashi Mori; Jun Tan
Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation.
Nature communications 2012;3():777.
2012: Yazhou Li; Mark P Mattson; Mohamed Mughal; Balmiki Ray; David Tweedie; Yun Wang; Daniel A Bruestle; Srinivasulu Chigurupati; Brandon K Harvey; Harold W Holloway; Debomoy K Lahiri; Nigel H Greig
Exendin-4 ameliorates motor neuron degeneration in cellular and animal models of amyotrophic lateral sclerosis.
PloS one 2012;7(2):e32008.
2012: Mali Jiang; Huan Cai; Ruth Luthi-Carter; Kellie L K Tamashiro; Jiangyang Zhang; Lin Du; Bronwen Martin; Susan Aja; Susumu Mori; Christopher A Ross; Timothy H Moran; Stuart Maudsley; Lan Xiang; David M Holtzman; Mark P Mattson; Jiawei Wang; Qi Peng; Tamara Seredenina; Katherine Sommers; Hyunkyung Jeong; Zhipeng Hou; X William Yang; nicolas arbez; Jennifer Qian; Tim West; Dimitri Krainc; Jinrong Fu; Robert H Cichewicz; Shanshan Zhu; WENZHEN DUAN
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
Nature medicine 2012;18(1):153-8.
2012: E M Kawamoto; Mark P Mattson; M Gleichmann; L M Yshii; L de Sá Lima; C Scavone
Effect of activation of canonical Wnt signaling by the Wnt-3a protein on the susceptibility of PC12 cells to oxidative and apoptotic insults.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2012;45(1):58-67.
2012: Alexis M Stranahan; Mark P Mattson
Metabolic reserve as a determinant of cognitive aging.
Journal of Alzheimer's disease : JAD 2012;30 Suppl 2():S5-13.
2012: Sarah J Texel; Erica L Unger; Bruce Ladenheim; Simonetta Camandola; Mohamed R Mughal; Jean Lud Cadet; Sarah M Rothman; Mark P Mattson
Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF.
Journal of neurochemistry 2012;120(1):125-34.
2012: Marc Gleichmann; Tali Kobilo; William R Markesbery; Mohamed R Mughal; Michael J Pazin; Juan C Troncoso; Henriette van Praag; William H Wood; Yongqing Zhang; Alan B Zonderman; Kevin G Becker; Mark P Mattson
Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks.
Neurobiology of aging 2012;33(1):205.e1-18.
2011: Ronald S Petralia; Catherine M Schwartz; Ya-Xian Wang; Mark P Mattson; Pamela J Yao
Subcellular localization of Patched and Smoothened, the receptors for Sonic hedgehog signaling, in the hippocampal neuron.
The Journal of comparative neurology 2011;519(18):3684-99.
2011: Linda A Henkel; Mark P Mattson
Reading is believing: the truth effect and source credibility.
Consciousness and cognition 2011;20(4):1705-21.
2011: Ronald S Petralia; Ya-Xian Wang; Mark P Mattson; Pamela J Yao
Sonic hedgehog distribution within mature hippocampal neurons.
Communicative & integrative biology 2011;4(6):775-7.
2011: Eun Ji Gong; Nam-Chul Ha; Dong-Gyu Jo; Mi Eun Kim; Eunjin Lee; Mark P Mattson; Hee Ra Park; Shunfu Piao; Hae Young Chung; Jaewon Lee
Morin attenuates tau hyperphosphorylation by inhibiting GSK3β.
Neurobiology of disease 2011;44(2):223-30.
2011: Alexis M Stranahan; Mark P Mattson
Bidirectional metabolic regulation of neurocognitive function.
Neurobiology of learning and memory 2011;96(4):507-16.
2011: Peisu Zhang; Michael J Pazin; Patricia Precht; Rebecca Casaday-Potts; Haiyang Jiang; Yie Liu; Mark P Mattson
Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(39):16434-9.
2011: Kathleen J Griffioen; Mark P Mattson
Playtime prevents obesity by brain-mediated fat browning.
Cell metabolism 2011;14(3):287-8.
2011: Grace E Stutzmann; Mark P Mattson
Endoplasmic reticulum Ca(2+) handling in excitable cells in health and disease.
Pharmacological reviews 2011;63(3):700-27.
2011: Jeong Seon Yoon; Mohamed R Mughal; Mark P Mattson
Energy restriction negates NMDA receptor antagonist efficacy in ischemic stroke.
Neuromolecular medicine 2011;13(3):175-8.
2011: Jenq-Lin Yang; Mark P Mattson; Peter Sykora; David M Wilson; Vilhelm A Bohr
The excitatory neurotransmitter glutamate stimulates DNA repair to increase neuronal resiliency.
Mechanisms of ageing and development 2011;132(8-9):405-11.
2011: Alexis M Stranahan; Richard Telljohann; Catherine Button; Roy G Cutler; Mark P Mattson
Diet-induced elevations in serum cholesterol are associated with alterations in hippocampal lipid metabolism and increased oxidative stress.
Journal of neurochemistry 2011;118(4):611-5.
2011: Mark P Mattson
Commentary: proteooxidotoxic process of aggregation.
Neuromolecular medicine 2011;13(2):91-2.
2011: Guang Qiu; Ruiqian Wan; Jingping Hu; Mark P Mattson; Edward Spangler; Shan Liu; Suk Yu Yau; Tatia M C Lee; Marc Gleichmann; Donald K Ingram; Kwok-Fai So; Sige Zou
Adiponectin protects rat hippocampal neurons against excitotoxicity.
Age (Dordrecht, Netherlands) 2011;33(2):155-65.
2011: Eitan Okun; Kathleen J Griffioen; Mark P Mattson
Toll-like receptor signaling in neural plasticity and disease.
Trends in neurosciences 2011;34(5):269-81.
2011: Clara Dees; Pawel Zerr; Michal Tomcik; Christian Beyer; Angelika Horn; Alfiya Akhmetshina; Katrin Palumbo; Nicole Reich; Jochen Zwerina; Michael Sticherling; Mark P Mattson; Oliver Distler; Georg Schett; Jörg H W Distler
Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.
Arthritis and rheumatism 2011;63(5):1396-404.
2011: Simonetta Camandola; Mark P Mattson
Aberrant subcellular neuronal calcium regulation in aging and Alzheimer's disease.
Biochimica et biophysica acta 2011;1813(5):965-73.
2011: Michelle N Harvie; M Pegington; Mark P Mattson; J Frystyk; B Dillon; Gareth Evans; J Cuzick; S A Jebb; B Martin; R G Cutler; T G Son; S Maudsley; O D Carlson; J M Egan; A Flyvbjerg; Anthony Howell
The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women.
International journal of obesity (2005) 2011;35(5):714-27.
2011: Jian-Min Zhang; Yue Wang; Zhikai Chi; Matthew J Keuss; Ying-Min Emily Pai; Ho Chul Kang; Joo-Ho Shin; Artem Bugayenko; Hong Wang; Yulan Xiong; Mikhail V Pletnikov; Mark P Mattson; Ted M Dawson; Valina Dawson
The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.
Cell 2011;145(2):284-99.
2011: Sarah J Texel; Mark P Mattson
Impaired adaptive cellular responses to oxidative stress and the pathogenesis of Alzheimer's disease.
Antioxidants & redox signaling 2011;14(8):1519-34.
2011: Marc Gleichmann; Mark P Mattson
Neuronal calcium homeostasis and dysregulation.
Antioxidants & redox signaling 2011;14(7):1261-73.
2011: Carola Romberg; Mark P Mattson; Mohamed R Mughal; Timothy J Bussey; Lisa M Saksida
Impaired attention in the 3xTgAD mouse model of Alzheimer's disease: rescue by donepezil (Aricept).
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(9):3500-7.
2011: Edward J Calabrese; Mark P Mattson
Hormesis provides a generalized quantitative estimate of biological plasticity.
Journal of cell communication and signaling 2011;5(1):25-38.
2011: Emmette Hutchison; Mark P Mattson
Eating less suppresses microRNA assassins in the brain.
Aging 2011;3(3):179-80.
2011: Asaff Harel; Mark P Mattson; Pamela J Yao
CALM, a clathrin assembly protein, influences cell surface GluR2 abundance.
Neuromolecular medicine 2011;13(1):88-90.
2011: Jeong Seon Yoon; Jong-Hwan Lee; Tae Gen Son; Mohamed R Mughal; Nigel H Greig; Mark P Mattson
Pregabalin suppresses calcium-mediated proteolysis and improves stroke outcome.
Neurobiology of disease 2011;41(3):624-9.
2011: Mark P Mattson
A lifetime of dedication to the old in his Kentucky home.
Neuromolecular medicine 2011;13(1):6-10.
2011: Mohamed R Mughal; Akanksha Baharani; Srinivasulu Chigurupati; Tae Gen Son; Edmund Chen; Peter Yang; Eitan Okun; Thiruma V Arumugam; Sic L Chan; Mark P Mattson
Electroconvulsive shock ameliorates disease processes and extends survival in huntingtin mutant mice.
Human molecular genetics 2011;20(4):659-69.
2011: Lavinia Alberi; Shuxi Liu; Yue Wang; Ramy Badie; CONSTANCE SMITH HICKS; Jing Wu; Tarran J Pierfelice; Bagrat Abazyan; Mark P Mattson; Dietmar Kuhl; Mikhail V Pletnikov; Paul F Worley; Nicholas Gaiano
Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks.
Neuron 2011;69(3):437-44.
2011: Dimitrios Kapogiannis; Mark P Mattson
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease.
Lancet neurology 2011;10(2):187-98.
2011: Dong Liu; Deborah L Croteau; Nadja C Souza-Pinto; Michael Pitta; Jingyan Tian; Christopher Wu; Haiyang Jiang; Khadija Mustafa; Guido Keijzers; Vilhelm A Bohr; Mark P Mattson
Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(2):680-92.
2011: Sarah J Texel; Erica L Unger; Jian-Min Zhang; Dennis D Taub; Simonetta Camandola; Z Leah Harris; Raymond C Koehler; Mark P Mattson
Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke.
PloS one 2011;6(9):e25077.
2011: Rebecca Casaday Potts; Patricia Precht; William H Wood; Andrea L Wurster; Peisu Zhang; Yonqing Zhang; Kevin G Becker; Mark P Mattson; Mohamed R Mughal; Michael J Pazin
CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes.
PloS one 2011;6(9):e24515.
2011: Piper R Hunt; Mark P Mattson; Tae Gen Son; Mark A Wilson; Kevin G Becker; Simonetta Camandola; Nigel H Greig; William H Wood; Qian-Sheng Yu; Yongqing Zhang; Catherine A Wolkow
Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms.
PloS one 2011;6(7):e21922.
2011: Vishwa Deep Dixit; Hyunwon Yang; Khaleel S Sayeed; Kim S Stote; William V Rumpler; David J Baer; Dan L Longo; Mark P Mattson; Dennis D Taub
Controlled meal frequency without caloric restriction alters peripheral blood mononuclear cell cytokine production.
Journal of inflammation (London, England) 2011;8():6.
2011: Srinivasulu Chigurupati; Meenu Madan; Eitan Okun; Zelan Wei; Jogi V Pattisapu; Mohamed R Mughal; Mark P Mattson; Sic L Chan
Evidence for altered Numb isoform levels in Alzheimer's disease patients and a triple transgenic mouse model.
Journal of Alzheimer's disease : JAD 2011;24(2):349-61.
2011: Marc Gleichmann; Vivian W Chow; Mark P Mattson
Homeostatic disinhibition in the aging brain and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24(1):15-24.
2011: Alexis M Stranahan; Thiruma V Arumugam; Mark P Mattson
Lowering corticosterone levels reinstates hippocampal brain-derived neurotropic factor and Trkb expression without influencing deficits in hypothalamic brain-derived neurotropic factor expression in leptin receptor-deficient mice.
Neuroendocrinology 2011;93(1):58-64.
2011: Kathleen J Griffioen; Ruiqian Wan; Eitan Okun; Xin Wang; Mary Rachael Lovett-Barr; Yazhou Li; Mohamed R Mughal; David Mendelowitz; Mark P Mattson
GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons.
Cardiovascular research 2011;89(1):72-8.
2010: Edward J Calabrese; Mark P Mattson; Vittorio Calabrese
Dose response biology: the case of resveratrol.
Human & experimental toxicology 2010;29(12):1034-7.
2010: Edward J Calabrese; Mark P Mattson; Vittorio Calabrese
Resveratrol commonly displays hormesis: occurrence and biomedical significance.
Human & experimental toxicology 2010;29(12):980-1015.
2010: Orly Lazarov; Mark P Mattson; Daniel A Peterson; Sanjay W Pimplikar; Henriette van Praag
When neurogenesis encounters aging and disease.
Trends in neurosciences 2010;33(12):569-79.
2010: Yongquan Luo; Mohamed R Mughal; Tae-Gen Son Xin Ouyang; Haiyang Jiang; Weiming Luo; Qian-Sheng Yu; Nigel H Greig; Mark P Mattson
Plumbagin promotes the generation of astrocytes from rat spinal cord neural progenitors via activation of the transcription factor Stat3.
Journal of neurochemistry 2010;115(6):1337-49.
2010: Vittorio Calabrese; Carolin Cornelius; Albena T Dinkova-Kostova; Edward J Calabrese; Mark P Mattson
Cellular stress responses, the hormesis paradigm, and vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders.
Antioxidants & redox signaling 2010;13(11):1763-811.
2010: Fangbai Wu; Mark P Mattson; Pamela J Yao
Neuronal activity and the expression of clathrin-assembly protein AP180.
Biochemical and biophysical research communications 2010;402(2):297-300.
2010: Alexis M Stranahan; Kim Lee; Kevin G Becker; Yonqing Zhang; Stuart Maudsley; Bronwen Martin; Roy G Cutler; Mark P Mattson
Hippocampal gene expression patterns underlying the enhancement of memory by running in aged mice.
Neurobiology of aging 2010;31(11):1937-49.
2010: Ismayil Ahmet; Ruiqian Wan; Mark P Mattson; Edward G Lakatta; Mark I Talan
Chronic alternate-day fasting results in reduced diastolic compliance and diminished systolic reserve in rats.
Journal of cardiac failure 2010;16(10):843-53.
2010: Mark P Mattson; D Kapogiannis; Nigel H Greig
Tweaking energy metabolism to prevent and treat neurological disorders.
Clinical pharmacology and therapeutics 2010;88(4):437-9.
2010: Dong-Hoon Hyun; Mohamed R Mughal; Hyunwon Yang; Ji Hyun Lee; Eun Joo Ko; Nicole D Hunt; Rafael de Cabo; Mark P Mattson
The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice.
Experimental neurology 2010;225(2):423-9.
2010: Mark P Mattson
Acetylation unleashes protein demons of dementia.
Neuron 2010;67(6):900-2.
2010: Catherine M Schwartz; Aiwu Cheng; Mohamed R Mughal; Mark P Mattson; Pamela J Yao
Clathrin assembly proteins AP180 and CALM in the embryonic rat brain.
The Journal of comparative neurology 2010;518(18):3803-18.
2010: Jenq-Lin Yang; Takashi Tadokoro; Guido Keijzers; Mark P Mattson; Vilhelm A Bohr
Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1.
The Journal of biological chemistry 2010;285(36):28191-9.
2010: Kotb Abdelmohsen; Emmette R Hutchison; Eun Kyung Lee; Yuki Kuwano; Mihee M Kim; Kiyoshi Masuda; Subramanya Srikantan; Sarah S Subaran; Bernard S Marasa; Mark P Mattson; Myriam Gorospe
miR-375 inhibits differentiation of neurites by lowering HuD levels.
Molecular and cellular biology 2010;30(17):4197-210.
2010: Byung-Joon Kim; Jie Zhou; Bronwen Martin; Olga Carlson; Stuart Maudsley; Nigel H Greig; Mark P Mattson; Ellen E Ladenheim; Jay Wustner; Andrew Turner; Homayoun Sadeghi; Josephine M Egan
Transferrin fusion technology: a novel approach to prolonging biological half-life of insulinotropic peptides.
The Journal of pharmacology and experimental therapeutics 2010;334(3):682-92.
2010: Eitan Okun; Kathleen Griffioen; Boaz Barak; Nicholas J Roberts; Kamilah Castro; Mario A Pita; Aiwu Cheng; Mohamed R Mughal; Ruiqian Wan; Uri Ashery; Mark P Mattson
Toll-like receptor 3 inhibits memory retention and constrains adult hippocampal neurogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(35):15625-30.
2010: Aiwu Cheng; Anna L Scott; Bruce Ladenheim; Kevin Chen; Xin Ouyang; Justin D Lathia; Mohamed R Mughal; Jean Lud Cadet; Mark P Mattson; Jean C Shih
Monoamine oxidases regulate telencephalic neural progenitors in late embryonic and early postnatal development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(32):10752-62.
2010: Norman Haughey; Veera Bandaru; Mihyun Bae; Mark P Mattson
Roles for dysfunctional sphingolipid metabolism in Alzheimer's disease neuropathogenesis.
Biochimica et biophysica acta 2010;1801(8):878-86.
2010: Ilias Kazanis; Justin D Lathia; Tegy John vadakkan; Eric Raborn; Ruiqian Wan; Mohamed R Mughal; D Mark Eckley; Takako Sasaki; Bruce L Patton; Mark P Mattson; Karen K Hirschi; Mary E Dickinson; Charles ffrench-Constant
Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(29):9771-81.
2010: Eitan Okun; Kathleen J Griffioen; Tae Gen Son; Jong-Hwan Lee; Nicholas J Roberts; Mohamed R Mughal; Emmette Hutchison; Aiwu Cheng; Thiruma V Arumugam; Justin D Lathia; Henriette van Praag; Mark P Mattson
TLR2 activation inhibits embryonic neural progenitor cell proliferation.
Journal of neurochemistry 2010;114(2):462-74.
2010: Eric Norman; Roy G Cutler; Richard Flannery; Yue Wang; Mark P Mattson
Plasma membrane sphingomyelin hydrolysis increases hippocampal neuron excitability by sphingosine-1-phosphate mediated mechanisms.
Journal of neurochemistry 2010;114(2):430-9.
2010: Xiangru Xu; Mohamed R Mughal; F Scott Hall; Maria T G Perona; Paul J Pistell; Justin D Lathia; Srinivasulu Chigurupati; Kevin G Becker; Bruce Ladenheim; Laura E Niklason; George R. Uhl; Jean Lud Cadet; Mark P Mattson
Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior.
Journal of neurochemistry 2010;114(1):323-34.
2010: Antonio Terracciano; Bronwen Martin; D Ansari; T Tanaka; Luigi Ferrucci; Stuart Maudsley; Mark P Mattson; Paul T Costa
Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits.
Genes, brain, and behavior 2010;9(5):512-8.
2010: Alexis M Stranahan; Thiruma V Arumugam; Kim Lee; Mark P Mattson
Mineralocorticoid receptor activation restores medial perforant path LTP in diabetic rats.
Synapse (New York, N.Y.) 2010;64(7):528-32.
2010: Tinghuai Wu; Jane Tian; Roy G Cutler; Richard S Telljohann; David A Bernlohr; Mark P Mattson; James T Handa
Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells.
Laboratory investigation; a journal of technical methods and pathology 2010;90(6):963-5.
2010: Eun Kyung Lee; Hyeon Ho Kim; Yuki Kuwano; Kotb Abdelmohsen; Subramanya Srikantan; Sarah S Subaran; Marc Gleichmann; Mohamed R Mughal; Jennifer L Martindale; Xiaoling Yang; Paul F Worley; Mark P Mattson; Myriam Gorospe
hnRNP C promotes APP translation by competing with FMRP for APP mRNA recruitment to P bodies.
Nature structural & molecular biology 2010;17(6):732-9.
2010: Yazhou Li; David Tweedie; Mark P Mattson; Harold W Holloway; Nigel H Greig
Enhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells.
Journal of neurochemistry 2010;113(6):1621-31.
2010: Mark P Mattson
Genes and behavior interact to determine mortality in mice when food is scarce and competition fierce.
Aging cell 2010;9(3):448-9; discussion 450-2.
2010: Eitan Okun; Mark P Mattson; Thiruma V Arumugam
Involvement of Fc receptors in disorders of the central nervous system.
Neuromolecular medicine 2010;12(2):164-78.
2010: Tinghuai Wu; Jane Tian; Roy G Cutler; Richard S Telljohann; David A Bernlohr; Mark P Mattson; James T Handa
Knockdown of FABP5 mRNA decreases cellular cholesterol levels and results in decreased apoB100 secretion and triglyceride accumulation in ARPE-19 cells.
Laboratory investigation; a journal of technical methods and pathology 2010;90(6):906-14.
2010: Dong-Gyu Jo; Thiruma V Arumugam; Ha-Na Woo; Jong-Sung Park; Sung-Chun Tang; Mohamed Mughal; Dong-Hoon Hyun; Jun-Hyung Park; Yun-Hyung Choi; A-Ryeong Gwon; Simonetta Camandola; Aiwu Cheng; Huaibin Cai; Weihong Song; William R Markesbery; Mark P Mattson
Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.
Neurobiology of aging 2010;31(6):917-25.
2010: Bronwen Martin; Yu-Kyong Shin; Caitlin M White; Sunggoan Ji; Wook Kim; Olga Carlson; Joshua K Napora; Wayne Chadwick; Megan Chapter; James A Waschek; Mark P Mattson; Stuart Maudsley; Josephine M Egan
Vasoactive intestinal peptide-null mice demonstrate enhanced sweet taste preference, dysglycemia, and reduced taste bud leptin receptor expression.
Diabetes 2010;59(5):1143-52.
2010: Ruiqian Wan; Ismayil Ahmet; Martin Brown; Aiwu Cheng; Naomi Kamimura; Mark I Talan; Mark P Mattson
Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats.
The Journal of nutritional biochemistry 2010;21(5):413-7.
2010: Bronwen Martin; Sunggoan Ji; Stuart Maudsley; Mark P Mattson
"Control" laboratory rodents are metabolically morbid: why it matters.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(14):6127-33.
2010: Katherine Conant; Y Wang; Arek Szklarczyk; A Dudak; Mark P Mattson; S T Lim
Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation.
Neuroscience 2010;166(2):508-21.
2010: Vivian W Chow; Mark P Mattson; Philip C Wong; Marc Gleichmann
An overview of APP processing enzymes and products.
Neuromolecular medicine 2010;12(1):1-12.
2010: Tae Gen Son; Simonetta Camandola; Thiruma V Arumugam; Roy G Cutler; Richard S Telljohann; Mohamed R Mughal; Tyson A Moore; Weiming Luo; Qian-Sheng Yu; Delinda A Johnson; Jeffrey A Johnson; Nigel H Greig; Mark P Mattson
Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia.
Journal of neurochemistry 2010;112(5):1316-26.
2010: Sarah M Rothman; Mark P Mattson
Adverse stress, hippocampal networks, and Alzheimer's disease.
Neuromolecular medicine 2010;12(1):56-70.
2010: Marc Gleichmann; Mark P Mattson
Alzheimer's disease and neuronal network activity.
Neuromolecular medicine 2010;12(1):44-7.
2010: Alexis M Stranahan; Mark P Mattson
Selective vulnerability of neurons in layer II of the entorhinal cortex during aging and Alzheimer's disease.
Neural plasticity 2010;2010():108190.
2010: Aiwu Cheng; Yan Hou; Mark P Mattson
Mitochondria and neuroplasticity.
ASN neuro 2010;2(5):e00045.
2010: Dong Liu; Michael Pitta; Jong-Hwan Lee; Balmiki Ray; Debomoy K Lahiri; Katsutoshi Furukawa; Mohamed Mughal; Haiyang Jiang; Julissa Villarreal; Roy G Cutler; Nigel H Greig; Mark P Mattson
The KATP channel activator diazoxide ameliorates amyloid-β and tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;22(2):443-57.
2010: John Thundyil; Sung-Chun Tang; Eitan Okun; Kausik Shah; Vardan T Karamyan; Yu-I Li; Trent Woodruff; Stephen M Taylor; Dong-Gyu Jo; Mark P Mattson; Thiruma V Arumugam
Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death.
Experimental & translational stroke medicine 2010;2(1):15.
2010: Mark P Mattson
The impact of dietary energy intake on cognitive aging.
Frontiers in aging neuroscience 2010;2():5.
2010: Erin Golden; Ana Emiliano; Stuart Maudsley; B Gwen Windham; Olga Carlson; Josephine M Egan; Ira Driscoll; Luigi Ferrucci; Bronwen Martin; Mark P Mattson
Circulating brain-derived neurotrophic factor and indices of metabolic and cardiovascular health: data from the Baltimore Longitudinal Study of Aging.
PloS one 2010;5(4):e10099.
2010: Srinivasulu Chigurupati; Mohamed R Mughal; Sic L Chan; Thiruma V Arumugam; Akanksha Baharani; Sung-Chun Tang; Qian-Sheng Yu; Harold W Holloway; Ross Wheeler; Suresh Poosala; Nigel H Greig; Mark P Mattson
A synthetic uric acid analog accelerates cutaneous wound healing in mice.
PloS one 2010;5(4):e10044.
2010: Mark P Mattson
ER calcium and Alzheimer's disease: in a state of flux.
Science signaling 2010;3(114):pe10.
2010: Yazhou Li; Kara B Duffy; Mary Ann Ottinger; Balmiki Ray; Jason A Bailey; Harold W Holloway; David Tweedie; TracyAnn Perry; Mark P Mattson; Dimitrios Kapogiannis; Kumar Sambamurti; Debomoy K Lahiri; Nigel H Greig
GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(4):1205-19.
2010: Thiruma V Arumugam; Terry M Phillips; Aiwu Cheng; Christopher H Morrell; Mark P Mattson; Ruiqian Wan
Age and energy intake interact to modify cell stress pathways and stroke outcome.
Annals of neurology 2010;67(1):41-52.
2010: Alexandra Auffret; Vanessa Gautheron; Mark P Mattson; Jean Mariani; Catherine Rovira
Progressive age-related impairment of the late long-term potentiation in Alzheimer's disease presenilin-1 mutant knock-in mice.
Journal of Alzheimer's disease : JAD 2010;19(3):1021-33.
2010: Mark P Mattson
Perspective: Does brown fat protect against diseases of aging?
Ageing research reviews 2010;9(1):69-76.
2010: Justin D Lathia; Srinivasulu Chigurupati; John Thundyil; Pradeep K Selvaraj; Mohamed R Mughal; Trent Woodruff; Sic L Chan; Vardan T Karamyan; Mark P Mattson; Thiruma V Arumugam
Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke.
Experimental neurology 2010;221(1):107-14.
2009: Lior Weissman; Nadja C de Souza-Pinto; Mark P Mattson; Vilhelm A Bohr
DNA base excision repair activities in mouse models of Alzheimer's disease.
Neurobiology of aging 2009;30(12):2080-1.
2009: Peisu Zhang; Justin D Lathia; William A Flavahan; Jeremy Rich; Mark P Mattson
Squelching glioblastoma stem cells by targeting REST for proteasomal degradation.
Trends in neurosciences 2009;32(11):559-65.
2009: Jianghong Li; Srinivasulu Chigurupati; Rachana Agarwal; Mohamed R Mughal; Mark P Mattson; Kevin G Becker; William H Wood; Yongqing Zhang; Patrice J Morin
Possible angiogenic roles for claudin-4 in ovarian cancer.
Cancer biology & therapy 2009;8(19):1806-14.
2009: Mark P Mattson
Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.
Experimental gerontology 2009;44(10):625-33.
2009: Alexis M Stranahan; Kim Lee; Bronwen Martin; Stuart Maudsley; Erin Golden; Roy G Cutler; Mark P Mattson
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.
Hippocampus 2009;19(10):951-61.
2009: Karine Loulier; Justin D Lathia; Veronique Marthiens; Jenne Relucio; Mohamed R Mughal; Sung-Chun Tang; Turhan Coksaygan; Peter E Hall; Srinivasulu Chigurupati; Bruce L Patton; Holly Colognato; Mahendra S Rao; Mark P Mattson; Tarik F Haydar; Charles ffrench-Constant
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche.
PLoS biology 2009;7(8):e1000176.
2009: Haipeng Xue; Sen Wu; Sophia T Papadeas; Steve Spusta; Anna Maria Swistowska; Chad C MacArthur; Mark P Mattson; Nicholas J Maragakis; Mario R Capecchi; Mahendra S Rao; Xianmin Zeng; Ying Liu
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells.
Stem cells (Dayton, Ohio) 2009;27(8):1836-46.
2009: Vanessa Gautheron; Alexandra Auffret; Mark P Mattson; Jean Mariani; Béatrice Vernet-der Garabedian
A new and simple approach for genotyping Alzheimer's disease presenilin-1 mutant knock-in mice.
Journal of neuroscience methods 2009;181(2):235-40.
2009: Fangbai Wu; Yasuji Matsuoka; Mark P Mattson; Pamela J Yao
The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide.
Biochemical and biophysical research communications 2009;385(2):247-50.
2009: Eitan Okun; Justin D Lathia; Mark P Mattson
Adhesion- and migration-related side effects of phosphothioated CpG oligodeoxynucleotides.
Cell adhesion & migration 2009;3(3):272-4.
2009: Yue Wang; Nigel H Greig; Qian-Sheng Yu; Mark P Mattson
Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices.
Neurobiology of aging 2009;30(7):1061-8.
2009: C B Lu; W Fu; X Xu; Mark P Mattson
Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.
Neuroscience 2009;161(2):403-12.
2009: David Wheeler; Edward Knapp; Veera Bandaru; Yue Wang; David Knorr; Christophe Poirier; Mark P Mattson; Jonathan D Geiger; Norman Haughey
Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors.
Journal of neurochemistry 2009;109(5):1237-49.
2009: Eitan Okun; Mark P Mattson
Phosphothioated oligodeoxynucleotides induce nonspecific effects on neuronal cell adhesion in a growth substrate-dependent manner.
Journal of neuroscience research 2009;87(8):1947-52.
2009: Mark P Mattson; Stuart Maudsley
Live longer sans the AT1A receptor.
Cell metabolism 2009;9(5):403-5.
2009: Luca Giliberto; Roberta Borghi; Alessandra Piccini; Rosa Mangerini; Sandro Sorbi; Gabriella Cirmena; Anna Garuti; Bernardino Ghetti; Fabrizio Tagliavini; Mohamed R Mughal; Mark P Mattson; Xiongwei Zhu; Xinglong Wang; Michela Guglielmotto; Elena Tamagno; Massimo Tabaton
Mutant presenilin 1 increases the expression and activity of BACE1.
The Journal of biological chemistry 2009;284(14):9027-38.
2009: Marc Gleichmann; Leon P Collis; Peter J S Smith; Mark P Mattson
Simultaneous single neuron recording of O2 consumption, [Ca2+]i and mitochondrial membrane potential in glutamate toxicity.
Journal of neurochemistry 2009;109(2):644-55.
2009: Marwan Maalouf; Jong M Rho; Mark P Mattson
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies.
Brain research reviews 2009;59(2):293-315.
2009: Eitan Okun; Kathleen J Griffioen; Justin D Lathia; Sung-Chun Tang; Mark P Mattson; Thiruma V Arumugam
Toll-like receptors in neurodegeneration.
Brain research reviews 2009;59(2):278-92.
2009: Thiruma V Arumugam; Trent Woodruff; Justin D Lathia; P K Selvaraj; Mark P Mattson; S M Taylor
Neuroprotection in stroke by complement inhibition and immunoglobulin therapy.
Neuroscience 2009;158(3):1074-89.
2009: SEEMA GULYANI; Christopher J Earley; Simonetta Camandola; Stuart Maudsley; Sergi Ferré; Mohamed R Mughal; Bronwen Martin; Aiwu Cheng; Marc Gleichmann; Byron C Jones; Richard Allen; Mark P Mattson
Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.
Experimental neurology 2009;215(2):236-42.
2009: Bronwen Martin; Erin Golden; Olga Carlson; Paul Pistell; Jie Zhou; Wook Kim; Brittany P Frank; Sam Thomas; Wayne A Chadwick; Nigel H Greig; Gillian P Bates; Kirupa Sathasivam; Michel Bernier; Stuart Maudsley; Mark P Mattson; Josephine M Egan
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
Diabetes 2009;58(2):318-28.
2009: Yazhou Li; TracyAnn Perry; Mark S Kindy; Brandon K Harvey; David Tweedie; Harold W Holloway; Kathleen Powers; Hui Shen; Josephine M Egan; Kumar Sambamurti; Arnold Brossi; Debomoy K Lahiri; Mark P Mattson; Barry Hoffer; Yun Wang; Nigel H Greig
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1285-90.
2009: Emmette R Hutchison; Eitan Okun; Mark P Mattson
The therapeutic potential of microRNAs in nervous system damage, degeneration, and repair.
Neuromolecular medicine 2009;11(3):153-61.
2009: R Varma; Y Chai; Juan C Troncoso; J Gu; H Xing; S S Stojilkovic; Mark P Mattson; Norman Haughey
Amyloid-beta induces a caspase-mediated cleavage of P2X4 to promote purinotoxicity.
Neuromolecular medicine 2009;11(2):63-75.
2009: Tahereh Tavakoli; Xiangru Xu; Eric Derby; Yevgeniya Serebryakova; Yvonne Reid; Mahendra S Rao; Mark P Mattson; Wu Ma
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V.
BMC cell biology 2009;10():44.
2009: Daniel A Bruestle; Roy G Cutler; Richard S Telljohann; Mark P Mattson
Decline in daily running distance presages disease onset in a mouse model of ALS.
Neuromolecular medicine 2009;11(2):58-62.
2009: Dong Liu; Robert Gharavi; Michael Pitta; Marc Gleichmann; Mark P Mattson
Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons.
Neuromolecular medicine 2009;11(1):28-42.
2009: Bronwen Martin; Michele Pearson; Randall Brenneman; Erin Golden; William Wood; Vinayakumar Prabhu; Kevin G Becker; Mark P Mattson; Stuart Maudsley
Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment.
PloS one 2009;4(1):e4146.
2009: Mark P Mattson; Uri Ashery
No more brain tangles with DeltaNp73.
Trends in biochemical sciences 2009;34(1):6-8.
2008: Justin D Lathia; Eitan Okun; Sung-Chun Tang; Kathleen Griffioen; Aiwu Cheng; Mohamed R Mughal; Gloria Laryea; Pradeep K Selvaraj; Charles ffrench-Constant; Tim Magnus; Thiruma V Arumugam; Mark P Mattson
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(51):13978-84.
2008: Mark P Mattson; Marc Gleichmann; Aiwu Cheng
Mitochondria in neuroplasticity and neurological disorders.
Neuron 2008;60(5):748-66.
2008: Justin D Lathia; Mark P Mattson; Aiwu Cheng
Notch: from neural development to neurological disorders.
Journal of neurochemistry 2008;107(6):1471-81.
2008: Dong Liu; Michael Pitta; Mark P Mattson
Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction.
Annals of the New York Academy of Sciences 2008;1147():275-82.
2008: Mark P Mattson
Glutamate and neurotrophic factors in neuronal plasticity and disease.
Annals of the New York Academy of Sciences 2008;1144():97-112.
2008: Srinivasulu Chigurupati; Tae Gen Son; Dong-Hoon Hyun; Justin D Lathia; Mohamed R Mughal; Jason Savell; Shuan C Li; G P C Nagaraju; Sic L Chan; Thiruma V Arumugam; Mark P Mattson
Lifelong running reduces oxidative stress and degenerative changes in the testes of mice.
The Journal of endocrinology 2008;199(2):333-41.
2008: Arek Szklarczyk; Osefame Ewaleifoh; Jean-Claude Beique; Yue Wang; David Knorr; Norman Haughey; Tanya Malpica; Mark P Mattson; Richard Huganir; Katherine Conant
MMP-7 cleaves the NR1 NMDA receptor subunit and modifies NMDA receptor function.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(11):3757-67.
2008: Peisu Zhang; Michael J Pazin; Catherine M Schwartz; Kevin G Becker; Robert P Wersto; Caroline M Dilley; Mark P Mattson
Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells.
Current biology : CB 2008;18(19):1489-94.
2008: Ittai Bushlin; Ronald S Petralia; Fangbai Wu; Asaff Harel; Mohamed R Mughal; Mark P Mattson; Pamela J Yao
Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(41):10257-71.
2008: Wayne Chadwick; Tim Magnus; Bronwen Martin; Aleksander Keselman; Mark P Mattson; Stuart Maudsley
Targeting TNF-alpha receptors for neurotherapeutics.
Trends in neurosciences 2008;31(10):504-11.
2008: George A Kyriazis; Zelan Wei; Miriam Vandermey; Dong-Gyu Jo; Ouyang Xin; Mark P Mattson; Sic L Chan
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.
The Journal of biological chemistry 2008;283(37):25492-502.
2008: Yongquan Luo; Justin Lathia; Mohammed Mughal; Mark P Mattson
SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons.
The Journal of biological chemistry 2008;283(36):24789-800.
2008: Enika Nagababu; SEEMA GULYANI; Christopher J Earley; Roy G Cutler; Mark P Mattson; Joseph M Rifkind
Iron-deficiency anaemia enhances red blood cell oxidative stress.
Free radical research 2008;42(9):824-9.
2008: Avanti Kulkarni; Daniel R McNeill; Marc Gleichmann; Mark P Mattson; David Michael Wilson
XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells.
Nucleic acids research 2008;36(15):5111-21.
2008: Ilya Bezprozvanny; Mark P Mattson
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease.
Trends in neurosciences 2008;31(9):454-63.
2008: Sung-Chun Tang; Justin D Lathia; Pradeep K Selvaraj; Dong-Gyu Jo; Mohamed R Mughal; Aiwu Cheng; Dominic A Siler; William R Markesbery; Thiruma V Arumugam; Mark P Mattson
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal.
Experimental neurology 2008;213(1):114-21.
2008: Alexis M Stranahan; Kim Lee; Paul J Pistell; Christopher M Nelson; Nathaniel Readal; Marshall G Miller; Edward L Spangler; Donald Ingram; Mark P Mattson
Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels.
Neurobiology of learning and memory 2008;90(2):479-83.
2008: Wang Wang; Huaqiang Fang; Linda Groom; Aiwu Cheng; Wanrui Zhang; Jie Liu; Xianhua Wang; Kaitao Li; Peidong Han; Ming Zheng; Jinhu Yin; Weidong Wang; Mark P Mattson; Joseph Kao; Edward G Lakatta; Shey-Shing Sheu; Kunfu Ouyang; Ju Chen; Robert T Dirksen; Heping Cheng
Superoxide flashes in single mitochondria.
Cell 2008;134(2):279-90.
2008: Jenq-Lin Yang; Lior Weissman; Vilhelm A Bohr; Mark P Mattson
Mitochondrial DNA damage and repair in neurodegenerative disorders.
DNA repair 2008;7(7):1110-20.
2008: Yu-Kyong Shin; Bronwen Martin; Erin Golden; Cedrick D Dotson; Stuart Maudsley; Wook Kim; Hyeung-Jin Jang; Mark P Mattson; Daniel J Drucker; Josephine M Egan; Steven Munger
Modulation of taste sensitivity by GLP-1 signaling.
Journal of neurochemistry 2008;106(1):455-63.
2008: Manchang Liu; Yideng Liang; Srinivasulu Chigurupati; Justin D Lathia; Mikhail V Pletnikov; Zhaoli Sun; Michael T Crow; Christopher A Ross; Mark P Mattson; Hamid Rabb
Acute kidney injury leads to inflammation and functional changes in the brain.
Journal of the American Society of Nephrology : JASN 2008;19(7):1360-70.
2008: Bronwen Martin; Erin Golden; Olga Carlson; Josephine M Egan; Mark P Mattson; Stuart Maudsley
Caloric restriction: impact upon pituitary function and reproduction.
Ageing research reviews 2008;7(3):209-24.
2008: Alexis M Stranahan; Kim Lee; Mark P Mattson
Contributions of impaired hippocampal plasticity and neurodegeneration to age-related deficits in hormonal pulsatility.
Ageing research reviews 2008;7(3):164-76.
2008: Chiho Hirata-Fukae; Hui-Fang Li; Hyang-Sook Hoe; Audrey J Gray; S Sakura Minami; Katsuyoshi Hamada; Takako Niikura; Fang Hua; Hiroe Tsukagoshi-Nagai; Yuko Horikoshi-Sakuraba; Mohamed Mughal; G. William Rebeck; Frank M LaFerla; Mark P Mattson; Nobuhisa Iwata; Takaomi C Saido; William L Klein; karen duff; Paul S Aisen; Yasuji Matsuoka
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.
Brain research 2008;1216():92-103.
2008: So Jung Kim; Tae Gen Son; Hee Ra Park; Mikyung Park; Min-Sun Kim; Hyung Sik Kim; Hae Young Chung; Mark P Mattson; Jaewon Lee
Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus.
The Journal of biological chemistry 2008;283(21):14497-505.
2008: Yuko Yamada; Jane Tian; Yanqin Yang; Roy G Cutler; Tinghuai Wu; Richard S Telljohann; Mark P Mattson; James T Handa
Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells.
Journal of neurochemistry 2008;105(4):1187-97.
2008: Magdalena Juhaszova; Su Wang; Dmitry B Zorov; H Bradley Nuss; Marc Gleichmann; Mark P Mattson; STEVEN SOLLOTT
The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown.
Annals of the New York Academy of Sciences 2008;1123():197-212.
2008: Mark P Mattson; Henriette van Praag
TAGing APP constrains neurogenesis.
Nature cell biology 2008;10(3):249-50.
2008: Alexis M Stranahan; Thiruma V Arumugam; Roy G Cutler; Kim Lee; Josephine M Egan; Mark P Mattson
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons.
Nature neuroscience 2008;11(3):309-17.
2008: Asaff Harel; Fangbai Wu; Mark P Mattson; Christa M Morris; Pamela J Yao
Evidence for CALM in directing VAMP2 trafficking.
Traffic (Copenhagen, Denmark) 2008;9(3):417-29.
2008: Elisa Mitiko Kawamoto; Lucilia B Lepsch; M F C Boaventura; Carolina Demarchi Munhoz; L S Lima; L M Yshii; M C W Avellar; Rui Curi; Mark P Mattson; Cristoforo Scavone
Amyloid beta-peptide activates nuclear factor-kappaB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells.
Journal of neuroscience research 2008;86(4):845-60.
2008: Mark P Mattson
Hormesis and disease resistance: activation of cellular stress response pathways.
Human & experimental toxicology 2008;27(2):155-62.
2008: Elena Tamagno; Michela Guglielmotto; Manuela Aragno; Roberta Borghi; Riccardo Autelli; Luca Giliberto; Giuseppe Muraca; Oliviero Danni; Xiongwei Zhu; Mark A. Smith; George Perry; Dong-Gyu Jo; Mark P Mattson; Massimo Tabaton
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
Journal of neurochemistry 2008;104(3):683-95.
2008: Bronwen Martin; Erin Golden; Alex Keselman; Matthew Stone; Mark P Mattson; Josephine M Egan; Stuart Maudsley
Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body.
Histology and histopathology 2008;23(2):237-50.
2008: Zhihong Guo; Haiyang Jiang; Xiangru Xu; WENZHEN DUAN; Mark P Mattson
Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization.
The Journal of biological chemistry 2008;283(3):1754-63.
2008: Tim Magnus; Jessica Carmen; Jessica Deleon; Haipeng Xue; Andrea C Pardo; Angelo C Lepore; Mark P Mattson; Mahendra S Rao; Nicholas J Maragakis
Adult glial precursor proliferation in mutant SOD1G93A mice.
Glia 2008;56(2):200-8.
2008: Yu Sun; Huai Li; Ying Liu; Mark P Mattson; Mahendra S Rao; Ming Zhan
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation.
PloS one 2008;3(10):e3406.
2008: Wu Ma; Tara Tavakoli; Eric Derby; Yevgeniya Serebryakova; Mahendra S Rao; Mark P Mattson
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells.
BMC developmental biology 2008;8():90.
2008: Mark P Mattson
Awareness of hormesis will enhance future research in basic and applied neuroscience.
Critical reviews in toxicology 2008;38(7):633-9.
2008: Alexis M Stranahan; Eric D Norman; Kim Lee; Roy G Cutler; Richard S Telljohann; Josephine M Egan; Mark P Mattson
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats.
Hippocampus 2008;18(11):1085-8.
2008: Bronwen Martin; Michele Pearson; Randall Brenneman; Erin Golden; Alex Keselman; Titilola Iyun; Olga Carlson; Josephine M Egan; Kevin G Becker; William Wood; Vinayakumar Prabhu; Rafael de Cabo; Stuart Maudsley; Mark P Mattson
Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.
PloS one 2008;3(6):e2398.
2008: Tae Gen Son; Simonetta Camandola; Mark P Mattson
Hormetic dietary phytochemicals.
Neuromolecular medicine 2008;10(4):236-46.
2008: Alexis M Stranahan; Mark P Mattson
Impact of energy intake and expenditure on neuronal plasticity.
Neuromolecular medicine 2008;10(4):209-18.
2008: Mark P Mattson; Peisu Zhang; Aiwu Cheng
Telomere neurobiology.
Methods in molecular biology (Clifton, N.J.) 2008;438():185-96.
2008: Alexis M Stranahan; Kim Lee; Mark P Mattson
Central mechanisms of HPA axis regulation by voluntary exercise.
Neuromolecular medicine 2008;10(2):118-27.
2008: Yue Wang; Jayanth S Chandran; Huaibin Cai; Mark P Mattson
DJ-1 is essential for long-term depression at hippocampal CA1 synapses.
Neuromolecular medicine 2008;10(1):40-5.
2008: Mark P Mattson; Ruiqian Wan
Neurotrophic factors in autonomic nervous system plasticity and dysfunction.
Neuromolecular medicine 2008;10(3):157-68.
2008: Mark P Mattson
Hormesis defined.
Ageing research reviews 2008;7(1):1-7.
2008: Thiruma V Arumugam; Pradeep K Selvaraj; Trent Woodruff; Mark P Mattson
Targeting ischemic brain injury with intravenous immunoglobulin.
Expert opinion on therapeutic targets 2008;12(1):19-29.
2008: Mark P Mattson
Dietary factors, hormesis and health.
Ageing research reviews 2008;7(1):43-8.
2007: Justin D Lathia; Bruce L Patton; D Mark Eckley; Tim Magnus; Mohamed R Mughal; Takako Sasaki; Maeve A Caldwell; Mahendra S Rao; Mark P Mattson; Charles ffrench-Constant
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.
The Journal of comparative neurology 2007;505(6):630-43.
2007: Olga Carlson; Bronwen Martin; Kim S Stote; Erin Golden; Stuart Maudsley; Samer S Najjar; Luigi Ferrucci; Donald Ingram; Dan Longo; William V Rumpler; David J Baer; Josephine Egan; Mark P Mattson
Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women.
Metabolism: clinical and experimental 2007;56(12):1729-34.
2007: Justin D Lathia; Mahendra S Rao; Mark P Mattson; Charles ffrench-Constant
The microenvironment of the embryonic neural stem cell: lessons from adult niches?
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(12):3267-82.
2007: Jacob M Zahn; Suresh Poosala; Art B Owen; Donald Ingram; Ana Lustig; Arnell Carter; Ashani T Weeraratna; Dennis D Taub; Myriam Gorospe; Krystyna Mazan-Mamczarz; Edward G Lakatta; Kenneth R Boheler; Xiangru Xu; Mark P Mattson; Geppino Falco; Minoru S H Ko; David Schlessinger; Jeffrey Firman; Sarah K Kummerfeld; William H Wood; Alan B Zonderman; Stuart K Kim; Kevin G Becker
AGEMAP: a gene expression database for aging in mice.
PLoS genetics 2007;3(11):e201.
2007: Kazuyuki Takata; Chiho Hirata-Fukae; Amanda Becker; Saori Chishiro; Audrey J Gray; Kouhei Nishitomi; Andreas H Franz; Gaku Sakaguchi; Akira Kato; Mark P Mattson; Frank M LaFerla; Paul S Aisen; Yoshihisa Kitamura; Yasuji Matsuoka
Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration.
The European journal of neuroscience 2007;26(9):2458-68.
2007: Antonio Cherubini; Cristina Andres-Lacueva; Antonio Martin; Fulvio Lauretani; Angelo Di Iorio; Benedetta Bartali; Annamaria Corsi; Stefania Bandinelli; Mark P Mattson; Luigi Ferrucci
Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(10):1120-6.
2007: Bronwen Martin; Michele Pearson; Lisa Kebejian; Erin Golden; Alex Keselman; Meredith Bender; Olga Carlson; Josephine Egan; Bruce Ladenheim; Jean Lud Cadet; Kevin G Becker; William Wood; Kara Duffy; Prabhu Vinayakumar; Stuart Maudsley; Mark P Mattson
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess.
Endocrinology 2007;148(9):4318-33.
2007: Thiruma V Arumugam; Sung-Chun Tang; Justin D Lathia; Aiwu Cheng; Mohamed R Mughal; Srinivasulu Chigurupati; Tim Magnus; Sic L Chan; Dong-Gyu Jo; Xin Ouyang; David P Fairlie; Daniel N Granger; Alexander O Vortmeyer; Milan Basta; Mark P Mattson
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14104-9.
2007: Sung-Chun Tang; Thiruma V Arumugam; Xiangru Xu; Aiwu Cheng; Mohamed R Mughal; Dong-Gyu Jo; Justin D Lathia; Dominic A Siler; Srinivasulu Chigurupati; Xin Ouyang; Tim Magnus; Simonetta Camandola; Mark P Mattson
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13798-803.
2007: Yongquan Luo; Haipeng Xue; Andrea C Pardo; Mark P Mattson; Mahendra S Rao; Nicholas J Maragakis
Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice.
Journal of neuroscience research 2007;85(11):2422-32.
2007: Eitan Okun; Thiruma V Arumugam; Sung-Chun Tang; Marc Gleichmann; Michael Albeck; Benjamin Sredni; Mark P Mattson
The organotellurium compound ammonium trichloro(dioxoethylene-0,0') tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice.
Journal of neurochemistry 2007;102(4):1232-41.
2007: Tim Magnus; Turhan Coksaygan; Thomas Korn; Haipeng Xue; Thiruma V Arumugam; Mohamed R Mughal; D Mark Eckley; Sung-Chun Tang; Louis J DeTolla; Mahendra S Rao; Riccardo Cassiani Ingoni; Mark P Mattson
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.
Journal of neuroscience research 2007;85(10):2126-37.
2007: So Jung Kim; Tae Gen Son; Keunho Kim; Hee Ra Park; Mark P Mattson; Jaewon Lee
Interferon-gamma promotes differentiation of neural progenitor cells via the JNK pathway.
Neurochemical research 2007;32(8):1399-406.
2007: Riccardo Cassiani Ingoni; Paolo A Muraro; Tim Magnus; Susan Reichert-Scrivner; Jens Schmidt; Jaebong Huh; Jacqueline A Quandt; Andras Bratincsak; Tal Shahar; Fabrizio Eusebi; Larry S Sherman; Mark P Mattson; Roland Martin; Mahendra S Rao
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response.
Journal of neuropathology and experimental neurology 2007;66(7):637-49.
2007: edward Calabrese; Kenneth A Bachmann; A John Bailer; P Michael Bolger; JONATHAN BORAK; Lu Cai; Nina Cedergreen; M George Cherian; Chuang C Chiueh; Thomas W Clarkson; Ralph R Cook; David M Diamond; David J Doolittle; Michael A Dorato; Stephen O Duke; Ludwig Feinendegen; Donald E Gardner; Ronald W Hart; Kenneth L Hastings; A Wallace Hayes; George R Hoffmann; John Ives; Zbigniew Jaworowski; Thomas Johnson; Wayne Jonas; Norbert E Kaminski; John G Keller; James E Klaunig; Thomas B Knudsen; Walter J Kozumbo; Teresa Lettieri; Shu-Zheng Liu; Andre Maisseu; Kenneth I Maynard; Edward J Masoro; Roger O McClellan; Harihara M Mehendale; Carmel Mothersill; David B Newlin; Herbert N Nigg; Frederick W Oehme; Robert F Phalen; Martin A Philbert; Suresh I S Rattan; Jim E Riviere; Joseph Rodricks; Robert M Sapolsky; Bobby R Scott; Colin Seymour; David A Sinclair; Joan Smith-Sonneborn; Elizabeth T Snow; Linda Spear; Donald E Stevenson; Yolene Thomas; Maurice Tubiana; Gary M Williams; Mark P Mattson
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework.
Toxicology and applied pharmacology 2007;222(1):122-8.
2007: Jessica Carmen; Tim Magnus; Riccardo Cassiani Ingoni; Larry S Sherman; Mahendra S Rao; Mark P Mattson
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS.
Progress in neurobiology 2007;82(3):151-62.
2007: Mark P Mattson
Calcium and neurodegeneration.
Aging cell 2007;6(3):337-50.
2007: Benjamin Sredni; Revital Geffen-Aricha; WENZHEN DUAN; Michael Albeck; Frances Shalit; Harry M Lander; Noa Kinor; Ortal Sagi; Amnon Albeck; Sigal Yosef; Miri Brodsky; Dvora Sredni-Kenigsbuch; Tali Sonino; Dan Longo; Mark P Mattson; Gal Yadid
Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1870-83.
2007: Veera Bandaru; justin charles mcarthur; Ned Sacktor; Roy G Cutler; E L Knapp; Mark P Mattson; Norman Haughey
Associative and predictive biomarkers of dementia in HIV-1-infected patients.
Neurology 2007;68(18):1481-7.
2007: Rhonda L Nelson; Zhihong Guo; Veerendra Madala Halagappa; Michelle Pearson; Audrey J Gray; Yasuji Matsuoka; Martin Brown; Bronwen Martin; Titilola Iyun; Stuart Maudsley; Robert F Clark; Mark P Mattson
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice.
Experimental neurology 2007;205(1):166-76.
2007: Sung-Chun Tang; Thiruma V Arumugam; Roy G Cutler; Dong-Gyu Jo; Tim Magnus; Sic L Chan; Mohamed R Mughal; Richard S Telljohann; Matthew Nassar; Xin Ouyang; Andrea Calderan; Paolo Ruzza; Andrea Guiotto; Mark P Mattson
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
Journal of neurochemistry 2007;101(3):729-36.
2007: Peisu Zhang; C Dilley; Mark P Mattson
DNA damage responses in neural cells: Focus on the telomere.
Neuroscience 2007;145(4):1439-48.
2007: Aiwu Cheng; Kazuo Shin-ya; Ruiqian Wan; Sung-Chun Tang; Takumi Miura; Hongyang Tang; Rina Khatri; Marc Gleichman; Xin Ouyang; Dong Liu; Hae-Rong Park; Jeffrey Y Chiang; Mark P Mattson
Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(14):3722-33.
2007: Kim S Stote; David J Baer; Karen Spears; David R Paul; G Keith Harris; William V Rumpler; Pilar Strycula; Samer S Najjar; Luigi Ferrucci; Donald Ingram; Dan Longo; Mark P Mattson
A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.
The American journal of clinical nutrition 2007;85(4):981-8.
2007: Veerendra Kumar Madala Halagappa; Zhihong Guo; Michelle Pearson; Yasuji Matsuoka; Roy G Cutler; Frank M LaFerla; Mark P Mattson
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
Neurobiology of disease 2007;26(1):212-20.
2007: Mark P Mattson
Mitochondrial regulation of neuronal plasticity.
Neurochemical research 2007;32(4-5):707-15.
2007: James B Johnson; Warren Summer; Roy G Cutler; Bronwen Martin; Dong-Hoon Hyun; Vishwa D Dixit; Michelle Pearson; Matthew Nassar; Richard Telljohann; Richard Tellejohan; Stuart Maudsley; Olga Carlson; Sujit John; Donald R Laub; Mark P Mattson
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.
Free radical biology & medicine 2007;42(5):665-74.
2007: Aiwu Cheng; Turhan Coksaygan; Hongyan Tang; Rina Khatri; Rita J Balice-Gordon; Mahendra S Rao; Mark P Mattson
Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism.
Journal of neurochemistry 2007;100(6):1515-30.
2007: Dong-Hoon Hyun; Nicole D Hunt; Scott S Emerson; Joe O Hernandez; Mark P Mattson; Rafael de Cabo
Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.
Journal of neurochemistry 2007;100(5):1364-74.
2007: Aiwu Cheng; Thiruma V Arumugam; Dong Liu; Rina Khatri; Khadija Mustafa; Seung Kwak; Huai-Ping Ling; Cathleen Gonzales; Ouyang Xin; Dong-Gyu Jo; Zhihong Guo; RJ Mark; Mark P Mattson
Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1519-28.
2007: Manuel Sánchez-Alavez; Sic L Chan; Mark P Mattson; José R Criado
Electrophysiological and cerebrovascular effects of the alpha-secretase-derived form of amyloid precursor protein in young and middle-aged rats.
Brain research 2007;1131(1):112-7.
2007: Soojung Shin; Haipeng Xue; Mark P Mattson; Mahendra S Rao
Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells.
Stem cells and development 2007;16(1):131-41.
2007: Simonetta Camandola; Mark P Mattson
NF-kappa B as a therapeutic target in neurodegenerative diseases.
Expert opinion on therapeutic targets 2007;11(2):123-32.
2007: David Michael Wilson; Mark P Mattson
Neurodegeneration: nicked to death.
Current biology : CB 2007;17(2):R55-8.
2007: Mark P Mattson; Tae Gen Son; Simonetta Camandola
Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals.
Dose-response : a publication of International Hormesis Society 2007;5(3):174-86.
2007: Srinivasulu Chigurupati; Thiruma V Arumugam; Tae Gen Son; Justin D Lathia; Shafaq Jameel; Mohamed R Mughal; Sung-Chun Tang; Dong-Gyu Jo; Simonetta Camandola; Marialuisa Giunta; Irina Rakova; Nazli McDonnell; Lucio Miele; Mark P Mattson; Suresh Poosala
Involvement of notch signaling in wound healing.
PloS one 2007;2(11):e1167.
2007: Frank Haberman; Sung-Chun Tang; Thiruma V Arumugam; Dong-Hoon Hyun; Qian-Sheng Yu; Roy G Cutler; Zhihong Guo; Harold W Holloway; Nigel H Greig; Mark P Mattson
Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice.
Neuromolecular medicine 2007;9(4):315-23.
2007: Xiangru Xu; Ming Zhan; WENZHEN DUAN; Vinayakumar Prabhu; Randall Brenneman; William Wood; Jeff Firman; Huai Li; Peisu Zhang; Carol Ibe; Alan B Zonderman; Dan Longo; Suresh Poosala; Kevin G Becker; Mark P Mattson
Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender.
Genome biology 2007;8(11):R234.
2007: Lior Weissman; Dong-Gyu Jo; Martin M Sørensen; Nadja C de Souza-Pinto; William R Markesbery; Mark P Mattson; Vilhelm A Bohr
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.
Nucleic acids research 2007;35(16):5545-55.
2007: Yasuji Matsuoka; Audrey J Gray; Chiho Hirata-Fukae; S Sakura Minami; Emily Graeme Waterhouse; Mark P Mattson; Frank M LaFerla; Illana Gozes; Paul S Aisen
Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage.
Journal of molecular neuroscience : MN 2007;31(2):165-70.
2007: Grant A Morgan; Qing Guo; Sic L Chan; Devin S Gary; Barbara A Osborne; Mark P Mattson
Defects of immune regulation in the presenilin-1 mutant knockin mouse.
Neuromolecular medicine 2007;9(1):35-45.
2007: Mark P Mattson; Roy G Cutler; Simonetta Camandola
Energy intake and amyotrophic lateral sclerosis.
Neuromolecular medicine 2007;9(1):17-20.
2007: Yu Sun; Huai Li; Ying Liu; Soojung Shin; Mark P Mattson; Mahendra S Rao; Ming Zhan
Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells.
Genomics 2007;89(1):22-35.
2007: Ann M Marini; Xueying Jiang; Xuan Wu; H Pan; Z Guo; Mark P Mattson; N Blondeau; A Novelli; Robert Henry Lipsky
Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli.
Amino acids 2007;32(3):299-304.
2006: Dong-Hoon Hyun; Scott S Emerson; Dong-Gyu Jo; Mark P Mattson; Rafael de Cabo
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19908-12.
2006: Sic L Chan; Dong Liu; George A Kyriazis; Pamela Bagsiyao; Xin Ouyang; Mark P Mattson
Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells.
The Journal of biological chemistry 2006;281(49):37391-403.
2006: Yue Wang; Jennifer Mackes; Stephen Chan; Norman Haughey; Zhihong Guo; Xin Ouyang; Katsutoshi Furukawa; Donald Ingram; Mark P Mattson
Impaired long-term depression in P2X3 deficient mice is not associated with a spatial learning deficit.
Journal of neurochemistry 2006;99(5):1425-34.
2006: Mark P Mattson
Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders.
Antioxidants & redox signaling 2006;8(11-12):1997-2006.
2006: Mark P Mattson; Aiwu Cheng
Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses.
Trends in neurosciences 2006;29(11):632-9.
2006: Roy G Cutler; Mark P Mattson
The adversities of aging.
Ageing research reviews 2006;5(3):221-38.
2006: Bronwen Martin; Mark P Mattson; Stuart Maudsley
Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
Ageing research reviews 2006;5(3):332-53.
2006: Amy R Furay; Erin K Murphy; Mark P Mattson; Z Guo; James P Herman
Region-specific regulation of glucocorticoid receptor/HSP90 expression and interaction in brain.
Journal of neurochemistry 2006;98(4):1176-84.
2006: Lary Walker; Harry LeVine; Mark P Mattson; Mathias Jucker
Inducible proteopathies.
Trends in neurosciences 2006;29(8):438-43.
2006: Mark P Mattson
Nitro-PDI incites toxic waste accumulation.
Nature neuroscience 2006;9(7):865-7.
2006: Jadwiga Turchan-Cholewo; Yiling Liu; Suzanne Gartner; Rollie Reid; Chunfa Jie; Xuejun Peng; Kuey Chu C Chen; Ashok Chauhan; Norman Haughey; Roy Cutler; Mark P Mattson; CARLOS PARDO-VILLAMIZAR; Katherine Conant; Ned Sacktor; justin charles mcarthur; Kurt F Hauser; C Gary Gairola; Avindra Nath
Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.
Neurobiology of disease 2006;23(1):109-19.
2006: Thiruma V Arumugam; Sic L Chan; Dong-Gyu Jo; Gokhan Yilmaz; Sung-Chun Tang; Aiwu Cheng; Marc Gleichmann; Eitan Okun; Vishwa Deep Dixit; Srinivasulu Chigurupati; Mohamed R Mughal; Xin Ouyang; Lucio Miele; Tim Magnus; Suresh Poosala; D Neil Granger; Mark P Mattson
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.
Nature medicine 2006;12(6):621-3.
2006: Jaewon Lee; So Jung Kim; Tae Gen Son; Sic L Chan; Mark P Mattson
Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity.
Journal of neuroscience research 2006;83(8):1552-7.
2006: Yongquan Luo; Jingli Cai; Haipeng Xue; Mark P Mattson; Mahendra S Rao
SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors.
Neuroscience letters 2006;398(3):291-5.
2006: Dong-Hoon Hyun; Joe O Hernandez; Mark P Mattson; Rafael de Cabo
The plasma membrane redox system in aging.
Ageing research reviews 2006;5(2):209-20.
2006: Thiruma V Arumugam; Marc Gleichmann; Sung-Chun Tang; Mark P Mattson
Hormesis/preconditioning mechanisms, the nervous system and aging.
Ageing research reviews 2006;5(2):165-78.
2006: Nicole D Hunt; Dong-Hoon Hyun; Joanne S Allard; Robin K Minor; Mark P Mattson; Donald Ingram; Rafael de Cabo
Bioenergetics of aging and calorie restriction.
Ageing research reviews 2006;5(2):125-43.
2006: Chengbiao Lu; Yue Wang; Katsutoshi Furukawa; Weiming Fu; Xin Ouyang; Mark P Mattson
Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses.
Journal of neurochemistry 2006;97(4):1104-10.
2006: Mark P Mattson; Mollie Katherine Meffert
Roles for NF-kappaB in nerve cell survival, plasticity, and disease.
Cell death and differentiation 2006;13(5):852-60.
2006: Jingli Cai; Soojung Shin; Lynda Wright; Ying Liu; Daixing Zhou; Haipeng Xue; Irina Khrebtukova; Mark P Mattson; Clive Svendsen; Mahendra S Rao
Massively parallel signature sequencing profiling of fetal human neural precursor cells.
Stem cells and development 2006;15(2):232-44.
2006: Stuart Maudsley; Mark P Mattson
Protein twists and turns in Alzheimer disease.
Nature medicine 2006;12(4):392-3.
2006: Donald E Mager; Ruiqian Wan; Martin Brown; Aiwu Cheng; Przemyslaw Wareski; Darrell R. Abernethy; Mark P Mattson
Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):631-7.
2006: Mark P Mattson; Tim Magnus
Ageing and neuronal vulnerability.
Nature reviews. Neuroscience 2006;7(4):278-94.
2006: Yunfeng Zhao; Li-ming Wang; Luksana Chaiswing; Hsiu-Chuan Yen; Terry D Oberley; Yu-Chin Lien; Shu-Mei Lin; Mark P Mattson; Daret St Clair
Tamoxifen protects against acute tumor necrosis factor alpha-induced cardiac injury via improving mitochondrial functions.
Free radical biology & medicine 2006;40(7):1234-41.
2006: Peisu Zhang; Katsutoshi Furukawa; Patricia L Opresko; Xiangru Xu; Vilhelm A Bohr; Mark P Mattson
TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.
Journal of neurochemistry 2006;97(2):567-81.
2006: Dong Liu; Sic L Chan; Nadja C de Souza-Pinto; John R Slevin; Robert P Wersto; Ming Zhan; Khadija Mustafa; Rafael de Cabo; Mark P Mattson
Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.
Neuromolecular medicine 2006;8(3):389-414.
2006: Yue Wang; Aiwu Cheng; Mark P Mattson
The PTEN phosphatase is essential for long-term depression of hippocampal synapses.
Neuromolecular medicine 2006;8(3):329-36.
2006: Ying Liu; Soojung Shin; Xianmin Zeng; Ming Zhan; Rodolfo Gonzalez; Franz-Josef Mueller; Catherine M Schwartz; Haipeng Xue; Huai Li; Shawn C Baker; Eugene Chudin; David L Barker; TK McDaniel; Steffen Oeser; Jeanne F Loring; Mark P Mattson; Mahendra S Rao
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines.
BMC developmental biology 2006;6():20.
2006: Huai Li; Ying Liu; Soojung Shin; Yu Sun; Jeanne F Loring; Mark P Mattson; Mahendra S Rao; Ming Zhan
Transcriptome coexpression map of human embryonic stem cells.
BMC genomics 2006;7():103.
2006: RICHARD SPENCER; Kenneth W Fishbein; Aiwu Cheng; Mark P Mattson
Compatibility of Gd-DTPA perfusion and histologic studies of the brain.
Magnetic resonance imaging 2006;24(1):27-31.
2006: Garrick D Lee; Dan Longo; Yue Wang; Joseph M Rifkind; Lilanie Abdul-Raman; Jacek A Mamczarz; Kara B Duffy; Edward L Spangler; Dennis D Taub; Mark P Mattson; Donald Ingram
Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):198-205.
2005: Ismayil Ahmet; Ruiqian Wan; Mark P Mattson; Edward G Lakatta; Mark I Talan
Cardioprotection by intermittent fasting in rats.
Circulation 2005;112(20):3115-21.
2005: Alexander McCampbell; David Truong; Daniel C Broom; Andrew J Allchorne; Ken Gable; Roy G Cutler; Mark P Mattson; Clifford J Woolf; Matthew P Frosch; Jeffrey M Harmon; Teresa M Dunn; Robert H Brown
Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.
Human molecular genetics 2005;14(22):3507-21.
2005: Mark P Mattson; Roy G Cutler; Dong-Gyu Jo
Alzheimer peptides perturb lipid-regulating enzymes.
Nature cell biology 2005;7(11):1045-7.
2005: Wenxue Li; David Galey; Mark P Mattson; Avindra Nath
Molecular and cellular mechanisms of neuronal cell death in HIV dementia.
Neurotoxicity research 2005;8(1-2):119-34.
2005: Mark P Mattson; Marc Gleichmann
The neuronal death protein par-4 mediates dopaminergic synaptic plasticity.
Molecular interventions 2005;5(5):278-81.
2005: Andrea Guiotto; Andrea Calderan; Paolo Ruzza; Alessio Osler; Chiara Rubini; Dong-Gyu Jo; Mark P Mattson; Gianfranco Borin
Synthesis and evaluation of neuroprotective alpha,beta-unsaturated aldehyde scavenger histidyl-containing analogues of carnosine.
Journal of medicinal chemistry 2005;48(19):6156-61.
2005: Mark P Mattson; Norman Haughey; Avindra Nath
Cell death in HIV dementia.
Cell death and differentiation 2005;12 Suppl 1():893-904.
2005: Inna I Kruman; Peter R Mouton; Roland Emokpae; Roy G Cutler; Mark P Mattson
Folate deficiency inhibits proliferation of adult hippocampal progenitors.
Neuroreport 2005;16(10):1055-9.
2005: Tohru Hasegawa; Wataru Ukai; Dong-Gyu Jo; Xiangru Xu; Mark P Mattson; Masaya Nakagawa; Wataru Araki; Toshikazu Saito; Tatsuo Yamada
Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeta42: implications for the pathogenesis of Alzheimer's disease.
Journal of neuroscience research 2005;80(6):869-76.
2005: Carsten Culmsee; Mark P Mattson
p53 in neuronal apoptosis.
Biochemical and biophysical research communications 2005;331(3):761-77.
2005: Simonetta Camandola; Roy G Cutler; Devin S Gary; Ollivier Milhavet; Mark P Mattson
Suppression of calcium release from inositol 1,4,5-trisphosphate-sensitive stores mediates the anti-apoptotic function of nuclear factor-kappaB.
The Journal of biological chemistry 2005;280(23):22287-96.
2005: Mark P Mattson
The need for controlled studies of the effects of meal frequency on health.
Lancet 2005;365(9475):1978-80.
2005: Mark P Mattson
NF-kappaB in the survival and plasticity of neurons.
Neurochemical research 2005;30(6-7):883-93.
2005: Dong Liu; Liejun Wu; Richard M Breyer; Mark P Mattson; Katrin Andreasson
Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia.
Annals of neurology 2005;57(5):758-61.
2005: Mark P Mattson; Ruiqian Wan
Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems.
The Journal of nutritional biochemistry 2005;16(3):129-37.
2005: Aneta T Petkova; Richard Leapman; Zhihong Guo; Wai-Ming Yau; Mark P Mattson; Robert Tycko
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils.
Science (New York, N.Y.) 2005;307(5707):262-5.
2005: Xiaoyan Sun; Vassilios Beglopoulos; Mark P Mattson; Jie Shen
Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
Neuro-degenerative diseases 2005;2(1):6-15.
2005: Thiruma V Arumugam; D Neil Granger; Mark P Mattson
Stroke and T-cells.
Neuromolecular medicine 2005;7(3):229-42.
2005: Bronwen Martin; Rakel Lopez de Maturana; Randall Brenneman; Tom Walent; Mark P Mattson; Stuart Maudsley
Class II G protein-coupled receptors and their ligands in neuronal function and protection.
Neuromolecular medicine 2005;7(1-2):3-36.
2005: Mark P Mattson
Energy intake, meal frequency, and health: a neurobiological perspective.
Annual review of nutrition 2005;25():237-60.
2005: Mark P Mattson
Human fetal brain cell culture.
Methods in molecular medicine 2005;107():163-71.
2004: Navin Maswood; Jennifer Young; Edward Tilmont; Zhiming Zhang; Don M Gash; Greg A Gerhardt; Richard Grondin; George S Roth; Julie A Mattison; Mark A Lane; Richard E Carson; Robert M Cohen; Peter R Mouton; Christopher Quigley; Mark P Mattson; Donald Ingram
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18171-6.
2004: Nigel H Greig; Mark P Mattson; TracyAnn Perry; Sic L Chan; Tony Giordano; Kumar Sambamurti; Jack T Rogers; Haim Ovadia; Debomoy K Lahiri
New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists.
Annals of the New York Academy of Sciences 2004;1035():290-315.
2004: Takumi Miura; Mark P Mattson; Mahendra S Rao
Cellular lifespan and senescence signaling in embryonic stem cells.
Aging cell 2004;3(6):333-43.
2004: Cathy W Levenson; Roy G Cutler; Bruce Ladenheim; Jean Lud Cadet; Joan Hare; Mark P Mattson
Role of dietary iron restriction in a mouse model of Parkinson's disease.
Experimental neurology 2004;190(2):506-14.
2004: Mark P Mattson; Stuart Maudsley; Bronwen Martin
A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin.
Ageing research reviews 2004;3(4):445-64.
2004: Inna I Kruman; Elena Schwartz; Yuri Kruman; Roy G Cutler; Xiaoxiang Zhu; Nigel H Greig; Mark P Mattson
Suppression of uracil-DNA glycosylase induces neuronal apoptosis.
The Journal of biological chemistry 2004;279(42):43952-60.
2004: Mark P Mattson; Dennis D Taub
Ancient viral protein enrages astrocytes in multiple sclerosis.
Nature neuroscience 2004;7(10):1021-3.
2004: Mark P Mattson; Stuart Maudsley; Bronwen Martin
BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders.
Trends in neurosciences 2004;27(10):589-94.
2004: Alexei Verkhratsky; Mark P Mattson; Emil Toescu
Aging in the mind.
Trends in neurosciences 2004;27(10):577-8.
2004: Thor D Stein; Nicholas J Anders; Charles DeCarli; Sic L Chan; Mark P Mattson; Jeffrey A Johnson
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(35):7707-17.
2004: Ruiqian Wan; Simonetta Camandola; Mark P Mattson
Dietary supplementation with 2-deoxy-D-glucose improves cardiovascular and neuroendocrine stress adaptation in rats.
American journal of physiology. Heart and circulatory physiology 2004;287(3):H1186-93.
2004: Roy G Cutler; Norman Haughey; A Tammara; justin charles mcarthur; Avindra Nath; R Reid; Diana Vargas; CARLOS PARDO-VILLAMIZAR; Mark P Mattson
Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.
Neurology 2004;63(4):626-30.
2004: Mark P Mattson
Pathways towards and away from Alzheimer's disease.
Nature 2004;430(7000):631-9.
2004: Malgorzata Chalimoniuk; Kelley King-Pospisil; Ward Anthony Pedersen; Andrzej Malecki; Edward Wylegala; Mark P Mattson; Bernhard Hennig; Michal J Toborek
Arachidonic acid increases choline acetyltransferase activity in spinal cord neurons through a protein kinase C-mediated mechanism.
Journal of neurochemistry 2004;90(3):629-36.
2004: Thomas V Getchell; Xuejun Peng; C Paul Green; Arnold J Stromberg; Kuey-Chu Chen; Mark P Mattson; Marilyn L Getchell
In silico analysis of gene expression profiles in the olfactory mucosae of aging senescence-accelerated mice.
Journal of neuroscience research 2004;77(3):430-52.
2004: Aiwu Cheng; Hongyan Tang; Jingli Cai; Min Zhu; Xiaoyu Zhang; Mahendra S Rao; Mark P Mattson
Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state.
Developmental biology 2004;272(1):203-16.
2004: Sic L Chan; Weiming Fu; Peisu Zhang; Aiwu Cheng; Jaewon Lee; Koichi Kokame; Mark P Mattson
Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.
The Journal of biological chemistry 2004;279(27):28733-43.
2004: Yue Wang; Sic L Chan; Lucio Miele; Pamela J Yao; Jennifer Mackes; Donald Ingram; Mark P Mattson; Katsutoshi Furukawa
Involvement of Notch signaling in hippocampal synaptic plasticity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9458-62.
2004: Charles Thompson; Devin S Gary; Mark P Mattson; Alex Mackenzie; George S Robertson
Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors.
Brain research. Molecular brain research 2004;123(1-2):126-31.
2004: WENZHEN DUAN; Zhihong Guo; Haiyang Jiang; Bruce Ladenheim; Xiangru Xu; Jean Lud Cadet; Mark P Mattson
Paroxetine retards disease onset and progression in Huntingtin mutant mice.
Annals of neurology 2004;55(4):590-4.
2004: Yue Wang; Norman Haughey; Mark P Mattson; Katsutoshi Furukawa
Dual effects of ATP on rat hippocampal synaptic plasticity.
Neuroreport 2004;15(4):633-6.
2004: Mark P Mattson
Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders.
Annals of the New York Academy of Sciences 2004;1012():37-50.
2004: Inna I Kruman; Robert P Wersto; Fernando Cardozo-Pelaez; Lubomir B Smilenov; Sic L Chan; Francis J Chrest; Roland Emokpae; Myriam Gorospe; Mark P Mattson
Cell cycle activation linked to neuronal cell death initiated by DNA damage.
Neuron 2004;41(4):549-61.
2004: Roy G Cutler; Jeremiah F Kelly; Kristin Storie; Ward Anthony Pedersen; Anita Tammara; Kimmo J Hatanpaa; Juan C Troncoso; Mark P Mattson
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2070-5.
2004: Norman Haughey; Roy G Cutler; Anita Tamara; justin charles mcarthur; Diana Vargas; CARLOS PARDO-VILLAMIZAR; Jadwiga Turchan; Avindra Nath; Mark P Mattson
Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia.
Annals of neurology 2004;55(2):257-67.
2004: Mark P Mattson; WENZHEN DUAN; Ruiqian Wan; Zhihong Guo
Prophylactic activation of neuroprotective stress response pathways by dietary and behavioral manipulations.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(1):111-6.
2004: Zhihong Guo; Titilola Iyun; Weiming Fu; Peisu Zhang; Mark P Mattson
Bone marrow transplantation reveals roles for brain macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death.
Neuromolecular medicine 2004;5(3):219-34.
2004: Mark P Mattson
Infectious agents and age-related neurodegenerative disorders.
Ageing research reviews 2004;3(1):105-20.
2004: Jingli Cai; Aiwu Cheng; Yongquan Luo; Chengbiao Lu; Mark P Mattson; Mahendra S Rao; Katsutoshi Furukawa
Membrane properties of rat embryonic multipotent neural stem cells.
Journal of neurochemistry 2004;88(1):212-26.
2003: Ollivier Milhavet; Devin S Gary; Mark P Mattson
RNA interference in biology and medicine.
Pharmacological reviews 2003;55(4):629-48.
2003: Mark P Mattson; Sic L Chan
Calcium orchestrates apoptosis.
Nature cell biology 2003;5(12):1041-3.
2003: Charles P Gilman; TracyAnn Perry; Katsotoshi Furukawa; Nigel H Grieg; Josephine M Egan; Mark P Mattson
Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons.
Journal of neurochemistry 2003;87(5):1137-44.
2003: Mark P Mattson
Adventures in neural plasticity, aging, and neurodegenerative disorders aboard the CWC beagle.
Neurochemical research 2003;28(11):1631-7.
2003: Katsutoshi Furukawa; Yue Wang; Pamela J Yao; Weiming Fu; Mark P Mattson; Yasuto Itoyama; Hiroshi Onodera; Ian D'Souza; Parvoneh Poorkaj-Navas; Thomas D Bird; Gerard D Schellenberg
Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation.
Journal of neurochemistry 2003;87(2):427-36.
2003: Mark P Mattson; Sic L Chan
Neuronal and glial calcium signaling in Alzheimer's disease.
Cell calcium 2003;34(4-5):385-97.
2003: Mark P Mattson; Frank Haberman
Folate and homocysteine metabolism: therapeutic targets in cardiovascular and neurodegenerative disorders.
Current medicinal chemistry 2003;10(19):1923-9.
2003: Mark P Mattson; Sic L Chan
Good and bad amyloid antibodies.
Science (New York, N.Y.) 2003;301(5641):1847-9.
2003: Carsten Culmsee; Jan Siewe; Vera Junker; Marina Retiounskaia; Stephanie Schwarz; Simonetta Camandola; Shahira El-Metainy; Hagen Behnke; Mark P Mattson; Josef Krieglstein
Reciprocal inhibition of p53 and nuclear factor-kappaB transcriptional activities determines cell survival or death in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(24):8586-95.
2003: Mark P Mattson
Gene-diet interactions in brain aging and neurodegenerative disorders.
Annals of internal medicine 2003;139(5 Pt 2):441-4.
2003: Mark P Mattson; TracyAnn Perry; Nigel H Greig
Learning from the gut.
Nature medicine 2003;9(9):1113-5.
2003: Dong Liu; John R Slevin; Chengbiao Lu; Sic L Chan; Magnus Hansson; Eskil Elmér; Mark P Mattson
Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.
Journal of neurochemistry 2003;86(4):966-79.
2003: Salvatore Oddo; Antonella Caccamo; Jason D Shepherd; Michael Murphy; todd golde; Rakez Kayed; Raju Metherate; Mark P Mattson; Yama Akbari; Frank M LaFerla
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
Neuron 2003;39(3):409-21.
2003: Mark P Mattson
Methylation and acetylation in nervous system development and neurodegenerative disorders.
Ageing research reviews 2003;2(3):329-42.
2003: Aiwu Cheng; Shuqin Wang; Jingli Cai; Mahendra S Rao; Mark P Mattson
Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain.
Developmental biology 2003;258(2):319-33.
2003: Gustavo Pigino; Gerardo Morfini; Alejandra Pelsman; Mark P Mattson; Scott T Brady; Jorge Busciglio
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(11):4499-508.
2003: David Galey; K Becker; Norman Haughey; A Kalehua; D Taub; J Woodward; Mark P Mattson; Avindra Nath
Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes.
Journal of neurovirology 2003;9(3):358-71.
2003: Ruiqian Wan; Simonetta Camandola; Mark P Mattson
Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats.
The Journal of nutrition 2003;133(6):1921-9.
2003: TracyAnn Perry; Debomoy K Lahiri; Kumar Sambamurti; Demao Chen; Mark P Mattson; Josephine M Egan; Nigel H Greig
Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.
Journal of neuroscience research 2003;72(5):603-12.
2003: WENZHEN DUAN; Zhihong Guo; Haiyang Jiang; Melvin Ware; Mark P Mattson
Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor.
Endocrinology 2003;144(6):2446-53.
2003: Ruiqian Wan; Simonetta Camandola; Mark P Mattson
Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1133-4.
2003: Robert Michael Anson; Zhihong Guo; Rafael de Cabo; Titilola Iyun; Michelle Rios; Adrienne Hagepanos; Donald Ingram; Mark A Lane; Mark P Mattson
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6216-20.
2003: Mark P Mattson; Dong Liu
Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death.
Biochemical and biophysical research communications 2003;304(3):539-49.
2003: Mark P Mattson; Guido Kroemer
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection.
Trends in molecular medicine 2003;9(5):196-205.
2003: Cristine Alves da Costa; Mark P Mattson; Karine Ancolio; Cristine Alves da Costa
The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
The Journal of biological chemistry 2003;278(14):12064-9.
2003: Thomas V Getchell; Xuejun Peng; Arnold J Stromberg; Kuey-Chu Chen; C Paul Green; Nishikant K Subhedar; Dharmen S Shah; Mark P Mattson; Marilyn L Getchell
Age-related trends in gene expression in the chemosensory-nasal mucosae of senescence-accelerated mice.
Ageing research reviews 2003;2(2):211-43.
2003: Peisu Zhang; Sic L Chan; Weiming Fu; Marty Mendoza; Mark P Mattson
TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):767-9.
2003: Mark P Mattson
Neurobiology: Ballads of a protein quartet.
Nature 2003;422(6930):385, 387.
2003: WENZHEN DUAN; Zhihong Guo; Haiyang Jiang; Melvin Ware; Xiao-Jiang Li; Mark P Mattson
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2911-6.
2003: Tobi L Limke; Jingli Cai; Takumi Miura; Mahendra S Rao; Mark P Mattson
Distinguishing features of progenitor cells in the late embryonic and adult hippocampus.
Developmental neuroscience 2003;25(2-4):257-72.
2003: Mark P Mattson; Thomas B Shea
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Trends in neurosciences 2003;26(3):137-46.
2003: Aiwu Cheng; Shuqin Wang; Dongmei Yang; Ruiping Xiao; Mark P Mattson
Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons.
The Journal of biological chemistry 2003;278(9):7591-9.
2003: Mark P Mattson
Will caloric restriction and folate protect against AD and PD?
Neurology 2003;60(4):690-5.
2003: Devin S Gary; Ollivier Milhavet; Simonetta Camandola; Mark P Mattson
Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons.
Journal of neurochemistry 2003;84(4):878-90.
2003: Mark P Mattson; WENZHEN DUAN; Zhihong Guo
Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms.
Journal of neurochemistry 2003;84(3):417-31.
2003: Mark P Mattson
Insulating axons via NF-kappaB.
Nature neuroscience 2003;6(2):105-6.
2003: Jaewon Lee; Wendy W Auyeung; Mark P Mattson
Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice.
Neuromolecular medicine 2003;4(3):179-96.
2003: Mark P Mattson; Michael Sherman
Perturbed signal transduction in neurodegenerative disorders involving aberrant protein aggregation.
Neuromolecular medicine 2003;4(1-2):109-32.
2003: John Q Trojanowski; Mark P Mattson
Overview of protein aggregation in single, double, and triple neurodegenerative brain amyloidoses.
Neuromolecular medicine 2003;4(1-2):1-6.
2003: Pamela J Yao; Peisu Zhang; Mark P Mattson; Katsutoshi Furukawa
Heterogeneity of endocytic proteins: distribution of clathrin adaptor proteins in neurons and glia.
Neuroscience 2003;121(1):25-37.
2003: Norman Haughey; Mark P Mattson
Alzheimer's amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytes.
Neuromolecular medicine 2003;3(3):173-80.
2003: Charles P Gilman; Sic L Chan; Zhihong Guo; Xiaoxiang Zhu; Nigel H Greig; Mark P Mattson
p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults.
Neuromolecular medicine 2003;3(3):159-72.
2003: Kirk J Pak; Sic L Chan; Mark P Mattson
Homocysteine and folate deficiency sensitize oligodendrocytes to the cell death-promoting effects of a presenilin-1 mutation and amyloid beta-peptide.
Neuromolecular medicine 2003;3(2):119-28.
2003: Mark P Mattson
Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders.
Neuromolecular medicine 2003;3(2):65-94.
2003: Kirk Pak; Sic L Chan; Mark P Mattson
Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice.
Neuromolecular medicine 2003;3(1):53-64.
2003: Avindra Nath; Elizabeth Hall; Marnia Tuzova; Michael Dobbs; Melina Jons; Caroline Anderson; Jerold Woodward; Zhihong Guo; Weiming Fu; Richard J Kryscio; David R Wekstein; Charles Smith; William R Markesbery; Mark P Mattson
Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development.
Neuromolecular medicine 2003;3(1):29-39.
2002: Weiming Fu; Chengbiao Lu; Mark P Mattson
Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(24):10710-9.
2002: Weiming Fu; Jaewon Lee; Zhihong Guo; Mark P Mattson
Seizures and tissue injury induce telomerase in hippocampal microglial cells.
Experimental neurology 2002;178(2):294-300.
2002: Mark P Mattson
Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's disease.
Journal of neurovirology 2002;8(6):539-50.
2002: Norman Haughey; Avindra Nath; Sic L Chan; A C Borchard; Mahendra S Rao; Mark P Mattson
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.
Journal of neurochemistry 2002;83(6):1509-24.
2002: Chengbiao Lu; Weiming Fu; Daohong Zhao; Mark P Mattson
The DNA damaging agent etoposide activates a cell survival pathway involving alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptors and mitogen-activated protein kinases in hippocampal neurons.
Journal of neuroscience research 2002;70(5):671-9.
2002: Xiaoxiang Zhu; Qian-Sheng Yu; Roy G Cutler; Carsten Culmsee; Harold W Holloway; Debomoy K Lahiri; Mark P Mattson; Nigel H Greig
Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.
Journal of medicinal chemistry 2002;45(23):5090-7.
2002: WENZHEN DUAN; Xiaoxiang Zhu; Bruce Ladenheim; Qian-Sheng Yu; Zhihong Guo; Jonathan M Oyler; Roy G Cutler; Jean Lud Cadet; Nigel H Greig; Mark P Mattson
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.
Annals of neurology 2002;52(5):597-606.
2002: Ollivier Milhavet; Jennifer L Martindale; Simonetta Camandola; Sic L Chan; Devin S Gary; Aiwu Cheng; Nikki J Holbrook; Mark P Mattson
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.
Journal of neurochemistry 2002;83(3):673-81.
2002: Sic L Chan; Carsten Culmsee; Norman Haughey; Wolfram Klapper; Mark P Mattson
Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Neurobiology of disease 2002;11(1):2-19.
2002: Norman Haughey; Mark P Mattson
Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.
Journal of acquired immune deficiency syndromes (1999) 2002;31 Suppl 2():S55-61.
2002: Roy G Cutler; Ward Anthony Pedersen; Simonetta Camandola; Jeffrey rothstein; Mark P Mattson
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis.
Annals of neurology 2002;52(4):448-57.
2002: Mark P Mattson; WENZHEN DUAN; Sic L Chan; Aiwu Cheng; Norman Haughey; Devin S Gary; Zhihong Guo; Jaewon Lee; Katsutoshi Furukawa
Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior.
Neurobiology of aging 2002;23(5):695-705.
2002: Jaewon Lee; WENZHEN DUAN; Mark P Mattson
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.
Journal of neurochemistry 2002;82(6):1367-75.
2002: TracyAnn Perry; Norman Haughey; Mark P Mattson; Josephine M Egan; Nigel H Greig
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.
The Journal of pharmacology and experimental therapeutics 2002;302(3):881-8.
2002: Ward Anthony Pedersen; Sic L Chan; Haiyan Zhu; Lilanie A Abdur-Rahman; Joseph M Verdi; Mark P Mattson
Numb isoforms containing a short PTB domain promote neurotrophic factor-induced differentiation and neurotrophic factor withdrawal-induced death of PC12 Cells.
Journal of neurochemistry 2002;82(4):976-86.
2002: Yue Wang; Mark P Mattson; Katsutoshi Furukawa
Endoplasmic reticulum calcium release is modulated by actin polymerization.
Journal of neurochemistry 2002;82(4):945-52.
2002: Katherine Conant; Norman Haughey; Avindra Nath; Coryse St Hillaire; Devin S Gary; CARLOS PARDO-VILLAMIZAR; Larry M Wahl; Masako M Bilak; Elizabeth Milward; Mark P Mattson
Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9.
Journal of neurochemistry 2002;82(4):885-93.
2002: Andreas C Tomac; Alan D Agulnick; Norman Haughey; Chen-Fu Chang; Yajun Zhang; Cristina Bäckman; Marisela Morales; Mark P Mattson; Yun Wang; Heiner Westphal; Barry Hoffer
Effects of cerebral ischemia in mice deficient in Persephin.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9521-6.
2002: Chengbiao Lu; Sic L Chan; Weiming Fu; Mark P Mattson
The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation.
The Journal of biological chemistry 2002;277(27):24368-75.
2002: Devin S Gary; Thomas V Getchell; Marilyn L Getchell; Mark P Mattson
Olfactory bulbectomy protects hippocampal pyramidal neurons against excitotoxic death.
Experimental neurology 2002;176(1):266-8.
2002: Mark P Mattson; Sic L Chan; WENZHEN DUAN
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior.
Physiological reviews 2002;82(3):637-72.
2002: Mark P Mattson; Elliot P Mattson
Amyloid peptide enhances nail rusting: novel insight into mechanisms of aging and Alzheimer's disease.
Ageing research reviews 2002;1(3):327-30.
2002: Guanjun Cheng; ZaiFang Yu; Daohong Zhou; Mark P Mattson
Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein.
Experimental neurology 2002;175(2):407-14.
2002: Smita Kittur; Skuntala Wilasrusmee; Ward Anthony Pedersen; Mark P Mattson; Karen Straube-West; Chumpon Wilasrusmee; Burk Lubelt; Dilip S Kittur
Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture.
Journal of molecular neuroscience : MN 2002;18(3):265-9.
2002: Peter J Van Ess; Samuel M Poloyac; Mark P Mattson; Robert A Blouin
Blunted induction of hepatic CYP4A in TNF (p55-/-/p75-/-) double receptor knockout mice following clofibrate treatment.
Pharmaceutical research 2002;19(5):708-12.
2002: Michael A LaFontaine; Mark P Mattson; D Allan Butterfield
Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.
Neurochemical research 2002;27(5):417-21.
2002: Jaewon Lee; Sic L Chan; Chengbiao Lu; Mark A Lane; Mark P Mattson
Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.
Experimental neurology 2002;175(1):161-7.
2002: Mark P Mattson
Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism.
Mechanisms of ageing and development 2002;123(8):947-53.
2002: Mark P Mattson; WENZHEN DUAN; Navin Maswood
How does the brain control lifespan?
Ageing research reviews 2002;1(2):155-65.
2002: Christina Lilliehook; S Chan; Eun-Kyoung Choi; Neeha Zaidi; Wilma Wasco; Mark P Mattson; Joseph Buxbaum
Calsenilin enhances apoptosis by altering endoplasmic reticulum calcium signaling.
Molecular and cellular neurosciences 2002;19(4):552-9.
2002: Dong Liu; Chengbiao Lu; Ruiqian Wan; Wendy W Auyeung; Mark P Mattson
Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):431-43.
2002: Cristine Alves da Costa; Erwan Paitel; Mark P Mattson; Robert Amson; Adam Telerman; Karine Ancolio; Cristine Alves da Costa; Marc P Mattson
Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):4043-8.
2002: Inna I Kruman; T Kumaravel; Althaf Lohani; Ward Anthony Pedersen; Roy G Cutler; Yuri Kruman; Norman Haughey; Jaewon Lee; Michele Evans; Mark P Mattson
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(5):1752-62.
2002: Peter J Van Ess; Mark P Mattson; Robert A Blouin
Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment.
The Journal of pharmacology and experimental therapeutics 2002;300(3):824-30.
2002: Mark P Mattson
Neurogenetics: white matter matters.
Trends in neurosciences 2002;25(3):135-6.
2002: Mark P Mattson; Inna I Kruman; WENZHEN DUAN
Folic acid and homocysteine in age-related disease.
Ageing research reviews 2002;1(1):95-111.
2002: Jaewon Lee; Kim B Seroogy; Mark P Mattson
Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice.
Journal of neurochemistry 2002;80(3):539-47.
2002: Peter J Van Ess; Ward Anthony Pedersen; Carsten Culmsee; Mark P Mattson; Robert A Blouin
Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease.
Journal of neurochemistry 2002;80(4):571-8.
2002: Mark P Mattson
Accomplices to neuronal death.
Nature 2002;415(6870):377-9.
2002: Ward Anthony Pedersen; Ruiqian Wan; Peisu Zhang; Mark P Mattson
Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(2):404-12.
2002: Devin S Gary; Mark P Mattson
PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis.
Neuromolecular medicine 2002;2(3):261-9.
2002: Mark P Mattson
Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease.
International review of neurobiology 2002;53():387-409.
2002: Carsten Culmsee; Norbert Gerling; M Lehmann; M Nikolova-Karakashian; Jochen H M Prehn; Mark P Mattson; Josef Krieglstein
Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.
Neuroscience 2002;115(4):1089-108.
2002: Mark P Mattson; Dong Liu
Energetics and oxidative stress in synaptic plasticity and neurodegenerative disorders.
Neuromolecular medicine 2002;2(2):215-31.
2002: Charles P Gilman; Mark P Mattson
Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility?
Neuromolecular medicine 2002;2(2):197-214.
2002: Sic L Chan; Katsutoshi Furukawa; Mark P Mattson
Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease.
Neuromolecular medicine 2002;2(2):167-96.
2002: Jaewon Lee; Sic L Chan; Mark P Mattson
Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain.
Neuromolecular medicine 2002;2(1):29-45.
2002: Mark P Mattson
Involvement of superoxide in pathogenic action of mutations that cause Alzheimer's disease.
Methods in enzymology 2002;352():455-74.
2002: Norman Haughey; Dong Liu; Avindra Nath; Amy C Borchard; Mark P Mattson
Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.
Neuromolecular medicine 2002;1(2):125-35.
2002: Chengbiao Lu; Weiming Fu; Guy S Salvesen; Mark P Mattson
Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: implications for synaptic plasticity and excitotoxic neuronal death.
Neuromolecular medicine 2002;1(1):69-79.
2002: Sic L Chan; Ward Anthony Pedersen; Hiayan Zhu; Mark P Mattson
Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease.
Neuromolecular medicine 2002;1(1):55-67.
2002: Mark P Mattson; Peisu Zhang; Weiming Fu
Assessing the involvement of telomerase in stem cell biology.
Methods in molecular biology (Clifton, N.J.) 2002;198():125-36.
2002: Yongquan Luo; Jeffrey M Long; Chengbiao Lu; Sic L Chan; Edward L Spangler; Paolo Mascarucci; Avraham Raz; Dan Longo; Mark P Mattson; Donald Ingram; Nan-ping Weng
A link between maze learning and hippocampal expression of neuroleukin and its receptor gp78.
Journal of neurochemistry 2002;80(2):354-61.
2002: WENZHEN DUAN; Bruce Ladenheim; Roy G Cutler; Inna I Kruman; Jean Lud Cadet; Mark P Mattson
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.
Journal of neurochemistry 2002;80(1):101-10.
2001: Chengbiao Lu; Weiming Fu; Mark P Mattson
Telomerase protects developing neurons against DNA damage-induced cell death.
Brain research. Developmental brain research 2001;131(1-2):167-71.
2001: Aiwu Cheng; Sic L Chan; Ollivier Milhavet; S Wang; Mark P Mattson
p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells.
The Journal of biological chemistry 2001;276(46):43320-7.
2001: Mark P Mattson
Stem cells as therapeutics for neurodegenerative disorders?
Expert review of neurotherapeutics 2001;1(2):267-73.
2001: Tomas A Prolla; Mark P Mattson
Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction.
Trends in neurosciences 2001;24(11 Suppl):S21-31.
2001: Mark P Mattson; Sic L Chan
Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits.
Journal of molecular neuroscience : MN 2001;17(2):205-24.
2001: Graham W Warren; Peter J Van Ess; AM Watson; Mark P Mattson; Robert A Blouin
Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(10):821-6.
2001: Zhihong Guo; Jaewon Lee; M Lane; Mark P Mattson
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2.
Journal of neurochemistry 2001;79(2):361-70.
2001: Carsten Culmsee; J Monnig; B E Kemp; Mark P Mattson
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.
Journal of molecular neuroscience : MN 2001;17(1):45-58.
2001: Mark P Mattson; Sic L Chan; Simonetta Camandola
Presenilin mutations and calcium signaling defects in the nervous and immune systems.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(8):733-44.
2001: Chengbiao Lu; Sic L Chan; Norman Haughey; W T Lee; Mark P Mattson
Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels.
Journal of neurochemistry 2001;78(3):577-89.
2001: Norman Haughey; Avindra Nath; Mark P Mattson; J T Slevin; Jonathan D Geiger
HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.
Journal of neurochemistry 2001;78(3):457-67.
2001: Mark P Mattson
A multi-talented secreted protein.
Trends in neurosciences 2001;24(8):441-2.
2001: Ward Anthony Pedersen; Ruiqian Wan; Mark P Mattson
Impact of aging on stress-responsive neuroendocrine systems.
Mechanisms of ageing and development 2001;122(9):963-83.
2001: Roy G Cutler; Mark P Mattson
Sphingomyelin and ceramide as regulators of development and lifespan.
Mechanisms of ageing and development 2001;122(9):895-908.
2001: Daohong Zhou; T Yu; G Chen; S A Brown; Z Yu; Mark P Mattson; J S Thompson
Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo.
International journal of radiation biology 2001;77(7):763-72.
2001: Chengbiao Lu; Mark P Mattson
Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons.
Experimental neurology 2001;170(1):180-5.
2001: GW Glazner; Simonetta Camandola; J D Geiger; Mark P Mattson
Endoplasmic reticulum D-myo-inositol 1,4,5-trisphosphate-sensitive stores regulate nuclear factor-kappaB binding activity in a calcium-independent manner.
The Journal of biological chemistry 2001;276(25):22461-7.
2001: Ward Anthony Pedersen; Deanna L McCullers; Carsten Culmsee; Norman Haughey; James P Herman; Mark P Mattson
Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease.
Neurobiology of disease 2001;8(3):492-503.
2001: Mark P Mattson
Lose weight STAT: CNTF tops leptin.
Trends in neurosciences 2001;24(6):313-4.
2001: Mark P Mattson; WENZHEN DUAN; J Lee; Z Guo
Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms.
Mechanisms of ageing and development 2001;122(7):757-78.
2001: Mahendra S Rao; Mark P Mattson
Stem cells and aging: expanding the possibilities.
Mechanisms of ageing and development 2001;122(7):713-34.
2001: Mark P Mattson; W Fu; P Zhang
Emerging roles for telomerase in regulating cell differentiation and survival: a neuroscientist's perspective.
Mechanisms of ageing and development 2001;122(7):659-71.
2001: Wolfram Klapper; T Shin; Mark P Mattson
Differential regulation of telomerase activity and TERT expression during brain development in mice.
Journal of neuroscience research 2001;64(3):252-60.
2001: Mark P Mattson
Neuronal death and GSK-3beta: a tau fetish?
Trends in neurosciences 2001;24(5):255-6.
2001: Carsten Culmsee; Y Zhu; J Krieglstein; Mark P Mattson
Evidence for the involvement of Par-4 in ischemic neuron cell death.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(4):334-43.
2001: C Lu; W Fu; Mark P Mattson
Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative disorders.
Neurobiology of disease 2001;8(2):194-206.
2001: Carsten Culmsee; Xiaoxiang Zhu; Qian-Sheng Yu; Sic L Chan; Simonetta Camandola; Zhihong Guo; Nigel H Greig; Mark P Mattson
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
Journal of neurochemistry 2001;77(1):220-8.
2001: C Culmsee; S Bondada; Mark P Mattson
Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.
Brain research. Molecular brain research 2001;87(2):257-62.
2001: Devin S Gary; Mark P Mattson
Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis.
Journal of neurochemistry 2001;76(5):1485-96.
2001: Rosario Garrido; Mark P Mattson; Bernhard Hennig; Michal J Toborek
Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons.
Journal of neurochemistry 2001;76(5):1395-403.
2001: WENZHEN DUAN; Jaewon Lee; Zhihong Guo; Mark P Mattson
Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury.
Journal of molecular neuroscience : MN 2001;16(1):1-12.
2001: Mark P Mattson; WENZHEN DUAN; Ward Anthony Pedersen; Carsten Culmsee
Neurodegenerative disorders and ischemic brain diseases.
Apoptosis : an international journal on programmed cell death 2001;6(1-2):69-81.
2001: Mark P Mattson
Does DNA damage sculpt the developing brain?
Trends in neurosciences 2001;24(2):77.
2001: Mark P Mattson; Simonetta Camandola
NF-kappaB in neuronal plasticity and neurodegenerative disorders.
The Journal of clinical investigation 2001;107(3):247-54.
2001: Mark P Mattson; Devin S Gary; Sic L Chan; WENZHEN DUAN
Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.
Biochemical Society symposium 2001;(67):151-62.
2001: Jadwiga Turchan; Carol Anderson; Kurt F Hauser; Q Sun; J Zhang; Yiling Liu; Phyllis M Wise; Inna I Kruman; William F Maragos; Mark P Mattson; Rosemarie M Booze; Avindra Nath
Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine.
BMC neuroscience 2001;2():3.
2001: WENZHEN DUAN; Zhihong Guo; Mark P Mattson
Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice.
Journal of neurochemistry 2001;76(2):619-26.
2001: Mark P Mattson; Wolfram Klapper
Emerging roles for telomerase in neuronal development and apoptosis.
Journal of neuroscience research 2001;63(1):1-9.
2001: Mark P Mattson
New blood cells help an overburdened brain.
Trends in neurosciences 2001;24(1):5.
2000: Simonetta Camandola; G Poli; Mark P Mattson
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
Brain research. Molecular brain research 2000;85(1-2):53-60.
2000: Mark P Mattson
Neuroprotective signaling and the aging brain: take away my food and let me run.
Brain research 2000;886(1-2):47-53.
2000: Jaewon Lee; James P Herman; Mark P Mattson
Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats.
Experimental neurology 2000;166(2):435-41.
2000: Mark P Mattson
Apoptosis in neurodegenerative disorders.
Nature reviews. Molecular cell biology 2000;1(2):120-9.
2000: Patrick G Sullivan; Jonathan D Geiger; Mark P Mattson; Stephen W Scheff
Dietary supplement creatine protects against traumatic brain injury.
Annals of neurology 2000;48(5):723-9.
2000: Z H Guo; Mark P Mattson
In vivo 2-deoxyglucose administration preserves glucose and glutamate transport and mitochondrial function in cortical synaptic terminals after exposure to amyloid beta-peptide and iron: evidence for a stress response.
Experimental neurology 2000;166(1):173-9.
2000: J Xie; Q Guo; H Zhu; M W Wooten; Mark P Mattson
Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide.
Brain research. Molecular brain research 2000;82(1-2):107-13.
2000: Jaewon Lee; WENZHEN DUAN; Jeffrey M Long; Donald Ingram; Mark P Mattson
Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.
Journal of molecular neuroscience : MN 2000;15(2):99-108.
2000: ZF Yu; Mariana Nikolova-Karakashian; Daohong Zhou; G Cheng; E H Schuchman; Mark P Mattson
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis.
Journal of molecular neuroscience : MN 2000;15(2):85-97.
2000: Mark P Mattson; Steven W Barger; Robert Dantzer
Silencing survival data.
Trends in neurosciences 2000;23(10):466-7.
2000: Annadora J Bruce-Keller; J L Keeling; Jeff Keller; FF Huang; S Camondola; Mark P Mattson
Antiinflammatory effects of estrogen on microglial activation.
Endocrinology 2000;141(10):3646-56.
2000: Inna I Kruman; Carsten Culmsee; Sic L Chan; Yuri Kruman; Zhihong Guo; L Penix; Mark P Mattson
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6920-6.
2000: WENZHEN DUAN; Z Guo; Mark P Mattson
Participation of par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid.
Experimental neurology 2000;165(1):1-11.
2000: Z Yu; Daohong Zhou; G Cheng; Mark P Mattson
Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease.
Journal of molecular neuroscience : MN 2000;15(1):31-44.
2000: Alexander G Rabchevsky; Isabella Fugaccia; A F Turner; Deborah A Blades; Mark P Mattson; Stephen W Scheff
Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat.
Experimental neurology 2000;164(2):280-91.
2000: Mark P Mattson
Turning off the anxiety master switch.
Trends in neurosciences 2000;23(8):333.
2000: Simonetta Camandola; Mark P Mattson
Pro-apoptotic action of PAR-4 involves inhibition of NF-kappaB activity and suppression of BCL-2 expression.
Journal of neuroscience research 2000;61(2):134-9.
2000: Mark P Mattson
Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy.
Experimental gerontology 2000;35(4):489-502.
2000: Mark P Mattson; C Culmsee; Z F Yu
Apoptotic and antiapoptotic mechanisms in stroke.
Cell and tissue research 2000;301(1):173-87.
2000: Mark P Mattson
Activin to the rescue for overexcited neurons.
Nature medicine 2000;6(7):739-41.
2000: Z Guo; A Ersoz; D Allan Butterfield; Mark P Mattson
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid.
Journal of neurochemistry 2000;75(1):314-20.
2000: H Zhu; Weiming Fu; Mark P Mattson
The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis.
Journal of neurochemistry 2000;75(1):117-24.
2000: GW Glazner; Simonetta Camandola; Mark P Mattson
Nuclear factor-kappaB mediates the cell survival-promoting action of activity-dependent neurotrophic factor peptide-9.
Journal of neurochemistry 2000;75(1):101-8.
2000: Sic L Chan; Michael Mayne; Clark P Holden; Jonathan D Geiger; Mark P Mattson
Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons.
The Journal of biological chemistry 2000;275(24):18195-200.
2000: Mark P Mattson; R C Haddon; Apparao M Rao
Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth.
Journal of molecular neuroscience : MN 2000;14(3):175-82.
2000: Andrzej Malecki; Rosario Garrido; Mark P Mattson; Bernhard Hennig; Michal J Toborek
4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons.
Journal of neurochemistry 2000;74(6):2278-87.
2000: Malcolm Leissring; Yama Akbari; CM Fanger; Michael D Cahalan; Mark P Mattson; Frank M LaFerla
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.
The Journal of cell biology 2000;149(4):793-8.
2000: GW Glazner; Sic L Chan; C Lu; Mark P Mattson
Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3641-9.
2000: Ward Anthony Pedersen; H Luo; Inna I Kruman; Edward J Kasarskis; Mark P Mattson
The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):913-24.
2000: Mark P Mattson; Frank M LaFerla; S L Chan; Malcolm Leissring; P Nickolas Shepel; Jonathan D Geiger
Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders.
Trends in neurosciences 2000;23(5):222-9.
2000: Marion R Steiner; Frederick W Holtsberg; Jeff Keller; Mark P Mattson; Sheldon M Steiner
Lysophosphatidic acid induction of neuronal apoptosis and necrosis.
Annals of the New York Academy of Sciences 2000;905():132-41.
2000: Mark P Mattson
Apoptotic and anti-apoptotic synaptic signaling mechanisms.
Brain pathology (Zurich, Switzerland) 2000;10(2):300-12.
2000: B C Albensi; Patrick G Sullivan; M B Thompson; Stephen W Scheff; Mark P Mattson
Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity.
Experimental neurology 2000;162(2):385-9.
2000: Ward Anthony Pedersen; Sic L Chan; Mark P Mattson
A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal.
Journal of neurochemistry 2000;74(4):1426-33.
2000: Z Guo; Mark S Kindy; Inna I Kruman; Mark P Mattson
ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):463-8.
2000: Mark P Mattson; H Zhu; Jin Yu; Mark S Kindy
Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(4):1358-64.
2000: Weiming Fu; Michael W Killen; Carsten Culmsee; S Dhar; T K Pandita; Mark P Mattson
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.
Journal of molecular neuroscience : MN 2000;14(1-2):3-15.
2000: Michal J Toborek; Rosario Garrido; Andrzej Malecki; Simone Kaiser; Mark P Mattson; Bernhard Hennig; Byron Young
Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons.
Experimental neurology 2000;161(2):609-20.
2000: GW Glazner; Mark P Mattson
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
Experimental neurology 2000;161(2):442-52.
2000: Mark P Mattson; Carsten Culmsee; Z Yu; Simonetta Camandola
Roles of nuclear factor kappaB in neuronal survival and plasticity.
Journal of neurochemistry 2000;74(2):443-56.
2000: B C Albensi; Mark P Mattson
Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity.
Synapse (New York, N.Y.) 2000;35(2):151-9.
2000: Devin S Gary; K Sooy; Sic L Chan; Sylvia Christakos; Mark P Mattson
Concentration- and cell type-specific effects of calbindin D28k on vulnerability of hippocampal neurons to seizure-induced injury.
Brain research. Molecular brain research 2000;75(1):89-95.
2000: Mark P Mattson
Existing data suggest that Alzheimer's disease is preventable.
Annals of the New York Academy of Sciences 2000;924():153-9.
2000: Avindra Nath; Carol Anderson; M Jones; William F Maragos; Rosemarie M Booze; Charles F Mactutus; J Bell; Kurt F Hauser; Mark P Mattson
Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia.
Journal of psychopharmacology (Oxford, England) 2000;14(3):222-7.
2000: Z H Guo; Mark P Mattson
Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function.
Cerebral cortex (New York, N.Y. : 1991) 2000;10(1):50-7.
2000: Simonetta Camandola; G Poli; Mark P Mattson
The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.
Journal of neurochemistry 2000;74(1):159-68.
1999: Jun Tan; Terrence Town; Daniel Paris; T Mori; Z Suo; Fiona Crawford; Mark P Mattson; R A Flavell; Michael Mullan
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.
Science (New York, N.Y.) 1999;286(5448):2352-5.
1999: GW Glazner; A Boland; Albert Dresse; Douglas E Brenneman; Illana Gozes; Mark P Mattson
Activity-dependent neurotrophic factor peptide (ADNF9) protects neurons against oxidative stress-induced death.
Journal of neurochemistry 1999;73(6):2341-7.
1999: Inna I Kruman; Ward Anthony Pedersen; Joe E Springer; Mark P Mattson
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Experimental neurology 1999;160(1):28-39.
1999: U Herbst; Michal J Toborek; S Kaiser; Mark P Mattson; Bernhard Hennig
4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells.
Journal of cellular physiology 1999;181(2):295-303.
1999: Z Yu; Daohong Zhou; Annadora J Bruce-Keller; Mark S Kindy; Mark P Mattson
Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(20):8856-65.
1999: WENZHEN DUAN; Zhiming Zhang; Don M Gash; Mark P Mattson
Participation of prostate apoptosis response-4 in degeneration of dopaminergic neurons in models of Parkinson's disease.
Annals of neurology 1999;46(4):587-97.
1999: Sic L Chan; Mark P Mattson
Caspase and calpain substrates: roles in synaptic plasticity and cell death.
Journal of neuroscience research 1999;58(1):167-90.
1999: Mark P Mattson; WENZHEN DUAN
"Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders.
Journal of neuroscience research 1999;58(1):152-66.
1999: Mark P Mattson; Annadora J Bruce-Keller
Compartmentalization of signaling in neurons: evolution and deployment.
Journal of neuroscience research 1999;58(1):2-9.
1999: H Zhu; Qing Guo; Mark P Mattson
Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation.
Brain research 1999;842(1):224-9.
1999: ZF Yu; Mark P Mattson
Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism.
Journal of neuroscience research 1999;57(6):830-9.
1999: D Zhang; Harbhajan S Dhillon; Mark P Mattson; David M Yurek; R M Prasad
Immunohistochemical detection of the lipid peroxidation product 4-hydroxynonenal after experimental brain injury in the rat.
Neuroscience letters 1999;272(1):57-61.
1999: Alexander G Rabchevsky; Isabella Fugaccia; Anita Fletcher-Turner; Deborah A Blades; Mark P Mattson; Stephen W Scheff
Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury.
Journal of neurotrauma 1999;16(9):817-30.
1999: Mark P Mattson
Establishment and plasticity of neuronal polarity.
Journal of neuroscience research 1999;57(5):577-89.
1999: M Tolar; Jeff Keller; S Chan; Mark P Mattson; Marcos A Marques; keith crutcher
Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(16):7100-10.
1999: Ward Anthony Pedersen; Carsten Culmsee; D Ziegler; James P Herman; Mark P Mattson
Aberrant stress response associated with severe hypoglycemia in a transgenic mouse model of Alzheimer's disease.
Journal of molecular neuroscience : MN 1999;13(1-2):159-65.
1999: Mark P Mattson; WENZHEN DUAN; Sic L Chan; Simonetta Camandola
Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders.
Journal of molecular neuroscience : MN 1999;13(1-2):17-30.
1999: Michal J Toborek; Andrzej Malecki; Rosario Garrido; Mark P Mattson; Bernhard Hennig; Byron Young
Arachidonic acid-induced oxidative injury to cultured spinal cord neurons.
Journal of neurochemistry 1999;73(2):684-92.
1999: Mark P Mattson; Z H Guo; Jonathan D Geiger
Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism.
Journal of neurochemistry 1999;73(2):532-7.
1999: Sic L Chan; Steven Tammariello; Steven Estus; Mark P Mattson
Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation.
Journal of neurochemistry 1999;73(2):502-12.
1999: Patrick G Sullivan; Annadora J Bruce-Keller; Alexander G Rabchevsky; Sylvia Christakos; D K Clair; Mark P Mattson; Stephen W Scheff
Exacerbation of damage and altered NF-kappaB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(15):6248-56.
1999: Sic L Chan; W S Griffin; Mark P Mattson
Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease.
Journal of neuroscience research 1999;57(3):315-23.
1999: WENZHEN DUAN; Mark P Mattson
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.
Journal of neuroscience research 1999;57(2):195-206.
1999: J Lee; Annadora J Bruce-Keller; Y Kruman; Sic L Chan; Mark P Mattson
2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.
Journal of neuroscience research 1999;57(1):48-61.
1999: Inna I Kruman; Avindra Nath; William F Maragos; Sic L Chan; Melina Jones; V M Rangnekar; RJ Jakel; Mark P Mattson
Evidence that Par-4 participates in the pathogenesis of HIV encephalitis.
The American journal of pathology 1999;155(1):39-46.
1999: Ward Anthony Pedersen; Mark P Mattson
No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice.
Brain research 1999;833(1):117-20.
1999: Qing Guo; Weiming Fu; Frederick W Holtsberg; Sheldon M Steiner; Mark P Mattson
Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.
Journal of neuroscience research 1999;56(5):457-70.
1999: WENZHEN DUAN; Vivek M Rangnekar; Mark P Mattson
Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration.
Journal of neurochemistry 1999;72(6):2312-22.
1999: Jeff Keller; KB Hanni; S Prasad Gabbita; V Friebe; Mark P Mattson; Mark S Kindy
Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines.
Brain research 1999;830(1):10-5.
1999: Jeff Keller; KB Hanni; Ward Anthony Pedersen; Neil R Cashman; Mark P Mattson; S Prasad Gabbita; V Friebe; William R Markesbery
Opposing actions of native and oxidized lipoprotein on motor neuron-like cells.
Experimental neurology 1999;157(1):202-10.
1999: Mark P Mattson; James V Partin
Evidence for mitochondrial control of neuronal polarity.
Journal of neuroscience research 1999;56(1):8-20.
1999: Qing Guo; L Sebastian; Bryce L Sopher; MW Miller; GW Glazner; Carol B Ware; George M Martin; Mark P Mattson
Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):4125-30.
1999: Weiming Fu; Jim G Begley; Michael W Killen; Mark P Mattson
Anti-apoptotic role of telomerase in pheochromocytoma cells.
The Journal of biological chemistry 1999;274(11):7264-71.
1999: Jim G Begley; WENZHEN DUAN; S Chan; karen duff; Mark P Mattson
Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.
Journal of neurochemistry 1999;72(3):1030-9.
1999: Qing Guo; L Sebastian; Bryce L Sopher; MW Miller; Carol B Ware; George M Martin; Mark P Mattson
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
Journal of neurochemistry 1999;72(3):1019-29.
1999: Graham W Warren; Samuel M Poloyac; Devin S Gary; Mark P Mattson; Robert A Blouin
Hepatic cytochrome P-450 expression in tumor necrosis factor-alpha receptor (p55/p75) knockout mice after endotoxin administration.
The Journal of pharmacology and experimental therapeutics 1999;288(3):945-50.
1999: Z Yu; H Luo; Weiming Fu; Mark P Mattson
The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.
Experimental neurology 1999;155(2):302-14.
1999: Inna I Kruman; Mark P Mattson
Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis.
Journal of neurochemistry 1999;72(2):529-40.
1999: Matthias Endres; K Fink; J Zhu; Nancy Stagliano; Vimala Bondada; James W Geddes; T Azuma; Mark P Mattson; D J Kwiatkowski; Michael A Moskowitz
Neuroprotective effects of gelsolin during murine stroke.
The Journal of clinical investigation 1999;103(3):347-54.
1999: Roman Wernyj; Mark P Mattson; Sylvia Christakos
Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide.
Brain research. Molecular brain research 1999;64(1):69-79.
1999: Mark P Mattson; Ward Anthony Pedersen; WENZHEN DUAN; Carsten Culmsee; Simonetta Camandola
Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.
Annals of the New York Academy of Sciences 1999;893():154-75.
1999: Mark P Mattson
Impairment of membrane transport and signal transduction systems by amyloidogenic proteins.
Methods in enzymology 1999;309():733-46.
1999: James W Geddes; TL Tekirian; Mark P Mattson
N-terminus truncated beta-amyloid peptides and C-terminus truncated secreted forms of amyloid precursor protein: distinct roles in the pathogenesis of Alzheimer's disease.
Neurobiology of aging 1999;20(1):75-9; discussion 87.
1999: Annadora J Bruce-Keller; James W Geddes; Pamela E Knapp; R W McFall; Jeff Keller; Frederick W Holtsberg; S Parthasarathy; Sheldon M Steiner; Mark P Mattson
Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD.
Journal of neuroimmunology 1999;93(1-2):53-71.
1999: Ward Anthony Pedersen; Neil R Cashman; Mark P Mattson
The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells.
Experimental neurology 1999;155(1):1-10.
1999: Annadora J Bruce-Keller; Gloria Umberger; R McFall; Mark P Mattson
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults.
Annals of neurology 1999;45(1):8-15.
1999: Qing Guo; Weiming Fu; Bryce L Sopher; MW Miller; Carol B Ware; George M Martin; Mark P Mattson
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
Nature medicine 1999;5(1):101-6.
1999: LA Opanashuk; RJ Mark; J Porter; D Damm; Mark P Mattson; Kim B Seroogy
Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(1):133-46.
1998: Inna I Kruman; Avindra Nath; Mark P Mattson
HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.
Experimental neurology 1998;154(2):276-88.
1998: Devin S Gary; Annadora J Bruce-Keller; Mark S Kindy; Mark P Mattson
Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(12):1283-7.
1998: Jeff Keller; KB Hanni; Mark P Mattson; William R Markesbery
Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity.
Neuroreport 1998;9(16):3731-4.
1998: Mark P Mattson; Ward Anthony Pedersen
Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1998;16(7-8):737-53.
1998: Ward Anthony Pedersen; W Fu; Jeff Keller; William R Markesbery; S Appel; R G Smith; Edward J Kasarskis; Mark P Mattson
Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients.
Annals of neurology 1998;44(5):819-24.
1998: Mark P Mattson; James V Partin; Jim G Begley
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites.
Brain research 1998;807(1-2):167-76.
1998: W Fu; H Luo; Sampath Parthasarathy; Mark P Mattson
Catecholamines potentiate amyloid beta-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis.
Neurobiology of disease 1998;5(4):229-43.
1998: Patrick G Sullivan; Jeff Keller; Mark P Mattson; Stephen W Scheff
Traumatic brain injury alters synaptic homeostasis: implications for impaired mitochondrial and transport function.
Journal of neurotrauma 1998;15(10):789-98.
1998: R G Smith; Yvonne Henry; Mark P Mattson; Stanley H Appel
Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis.
Annals of neurology 1998;44(4):696-9.
1998: Frederick W Holtsberg; Marion R Steiner; Annadora J Bruce-Keller; Jeff Keller; Mark P Mattson; J C Moyers; Sheldon M Steiner
Lysophosphatidic acid and apoptosis of nerve growth factor-differentiated PC12 cells.
Journal of neuroscience research 1998;53(6):685-96.
1998: Jim G Begley; D Allan Butterfield; Jeff Keller; T Koppal; Jennifer Drake; Mark P Mattson
Cryopreservation of rat cortical synaptosomes and analysis of glucose and glutamate transporter activities, and mitochondrial function.
Brain research. Brain research protocols 1998;3(1):76-82.
1998: Mark P Mattson; Jeff Keller; Jim G Begley
Evidence for synaptic apoptosis.
Experimental neurology 1998;153(1):35-48.
1998: ZF Yu; Annadora J Bruce-Keller; Y Goodman; Mark P Mattson
Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo.
Journal of neuroscience research 1998;53(5):613-25.
1998: Qing Guo; Weiming Fu; J Xie; H Luo; Stephen F Sells; James W Geddes; Vimala Bondada; Vivek M Rangnekar; Mark P Mattson
Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.
Nature medicine 1998;4(8):957-62.
1998: Jeff Keller; Qing Guo; Frederick W Holtsberg; Annadora J Bruce-Keller; Mark P Mattson
Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4439-50.
1998: K Furukawa; Qing Guo; Gerard D Schellenberg; Mark P Mattson
Presenilin-1 mutation alters NGF-induced neurite outgrowth, calcium homeostasis, and transcription factor (AP-1) activation in PC12 cells.
Journal of neuroscience research 1998;52(5):618-24.
1998: Eliezer Masliah; Jacob Raber; Michael Alford; Margaret Mallory; Mark P Mattson; D Yang; D Wong; Lennart Mucke
Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis.
The Journal of biological chemistry 1998;273(20):12548-54.
1998: Qing Guo; N Robinson; Mark P Mattson
Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.
The Journal of biological chemistry 1998;273(20):12341-51.
1998: K Furukawa; Mark P Mattson
The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.
Journal of neurochemistry 1998;70(5):1876-86.
1998: Hideyuki J Majima; Terry D Oberley; K Furukawa; Mark P Mattson; Hsiu-Chuan Yen; Luke I Szweda; Daret K St Clair
Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death.
The Journal of biological chemistry 1998;273(14):8217-24.
1998: Qing Guo; Sylvia Christakos; N Robinson; Mark P Mattson
Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3227-32.
1998: Annadora J Bruce-Keller; Y J Li; Mark A Lovell; PJ Kraemer; Devin S Gary; R R Brown; William R Markesbery; Mark P Mattson
4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats.
Journal of neuropathology and experimental neurology 1998;57(3):257-67.
1998: EM Blanc; Annadora J Bruce-Keller; Mark P Mattson
Astrocytic gap junctional communication decreases neuronal vulnerability to oxidative stress-induced disruption of Ca2+ homeostasis and cell death.
Journal of neurochemistry 1998;70(3):958-70.
1998: K Furukawa; Mark P Mattson
Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP.
Neuroscience 1998;83(2):429-38.
1998: E M Blanc; Jeff Keller; S Fernandez; Mark P Mattson
4-hydroxynonenal, a lipid peroxidation product, impairs glutamate transport in cortical astrocytes.
Glia 1998;22(2):149-60.
1998: Mark P Mattson
Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity.
Trends in neurosciences 1998;21(2):53-7.
1998: Inna I Kruman; Qing Guo; Mark P Mattson
Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells.
Journal of neuroscience research 1998;51(3):293-308.
1998: Jeff Keller; Mark S Kindy; Frederick W Holtsberg; Daret K St Clair; Hsiu-Chuan Yen; A Germeyer; Sheldon M Steiner; Annadora J Bruce-Keller; J B Hutchins; Mark P Mattson
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(2):687-97.
1998: Mark P Mattson; K Furukawa
Signaling events regulating the neurodevelopmental triad. Glutamate and secreted forms of beta-amyloid precursor protein as examples.
Perspectives on developmental neurobiology 1998;5(4):337-52.
1998: Jeff Keller; Mark P Mattson
Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system.
Reviews in the neurosciences 1998;9(2):105-16.
1998: Mark P Mattson
Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF kappa B.
International review of neurobiology 1998;42():103-68.
1998: Frederick W Holtsberg; Marion R Steiner; Jeff Keller; RJ Mark; Mark P Mattson; Sheldon M Steiner
Lysophosphatidic acid induces necrosis and apoptosis in hippocampal neurons.
Journal of neurochemistry 1998;70(1):66-76.
1998: Annadora J Bruce-Keller; Jim G Begley; Weiming Fu; D Allan Butterfield; Dale E Bredesen; J B Hutchins; Kenneth Hensley; Mark P Mattson
Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide.
Journal of neurochemistry 1998;70(1):31-9.
1998: Mark P Mattson; Qing Guo; K Furukawa; Ward Anthony Pedersen
Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.
Journal of neurochemistry 1998;70(1):1-14.
1997: Mark P Mattson; N Robinson; Qing Guo
Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.
Neuroreport 1997;8(17):3817-21.
1997: Jeff Keller; A Germeyer; Jim G Begley; Mark P Mattson
17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron.
Journal of neuroscience research 1997;50(4):522-30.
1997: Mark P Mattson; Qing Guo
Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?
Journal of neuroscience research 1997;50(4):505-13.
1997: Mark P Mattson
Advances fuel Alzheimer's conundrum.
Nature genetics 1997;17(3):254-6.
1997: K Furukawa; Weiming Fu; Y Li; W Witke; D J Kwiatkowski; Mark P Mattson
The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8178-86.
1997: Mark P Mattson; Jim G Begley; RJ Mark; K Furukawa
Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms.
Brain research 1997;771(1):147-53.
1997: Michal J Toborek; EM Blanc; S Kaiser; Mark P Mattson; Bernhard Hennig
Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells.
Journal of lipid research 1997;38(10):2155-67.
1997: Mark P Mattson
Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives.
Physiological reviews 1997;77(4):1081-132.
1997: Jeff Keller; RJ Mark; AJ Bruce; EM Blanc; Jeffrey rothstein; K Uchida; G Waeg; Mark P Mattson
4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.
Neuroscience 1997;80(3):685-96.
1997: Mark P Mattson; Y Goodman; H Luo; Weiming Fu; K Furukawa
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Journal of neuroscience research 1997;49(6):681-97.
1997: Ward Anthony Pedersen; Qing Guo; B K Hartman; Mark P Mattson
Nerve growth factor-independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1.
The Journal of biological chemistry 1997;272(36):22397-400.
1997: Mark A Lovell; WD Ehmann; Mark P Mattson; William R Markesbery
Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.
Neurobiology of aging 1997;18(5):457-61.
1997: Mark P Mattson
Mother's legacy: mitochondrial DNA mutations and Alzheimer's disease.
Trends in neurosciences 1997;20(9):373-5.
1997: R Subramaniam; F Roediger; B Jordan; Mark P Mattson; Jeff Keller; G Waeg; D Allan Butterfield
The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins.
Journal of neurochemistry 1997;69(3):1161-9.
1997: Jeff Keller; Marion R Steiner; Frederick W Holtsberg; Mark P Mattson; Sheldon M Steiner
Lysophosphatidic acid-induced proliferation-related signals in astrocytes.
Journal of neurochemistry 1997;69(3):1073-84.
1997: Robert D Azbill; Xiaojun Mu; Annadora J Bruce-Keller; Mark P Mattson; Joe E Springer
Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury.
Brain research 1997;765(2):283-90.
1997: EM Blanc; Jeremiah F Kelly; RJ Mark; G Waeg; Mark P Mattson
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Journal of neurochemistry 1997;69(2):570-80.
1997: Mark P Mattson; W Fu; G Waeg; K Uchida
4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau.
Neuroreport 1997;8(9-10):2275-81.
1997: A Ishida; K Furukawa; Jeff Keller; Mark P Mattson
Secreted form of beta-amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices.
Neuroreport 1997;8(9-10):2133-7.
1997: S Lee; J Williamson; E W Lothman; F G Szele; Marie-Francoise Chesselet; Stanley Von Hagen; R M Sapolsky; Mark P Mattson; Sylvia Christakos
Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment.
Brain research. Molecular brain research 1997;47(1-2):183-94.
1997: Jeff Keller; Zhen Pang; James W Geddes; Jim G Begley; A Germeyer; G Waeg; Mark P Mattson
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.
Journal of neurochemistry 1997;69(1):273-84.
1997: Frederick W Holtsberg; Marion R Steiner; K Furukawa; Jeff Keller; Mark P Mattson; Sheldon M Steiner
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Journal of neurochemistry 1997;69(1):68-75.
1997: Steven W Barger; Mark P Mattson
Isoform-specific modulation by apolipoprotein E of the activities of secreted beta-amyloid precursor protein.
Journal of neurochemistry 1997;69(1):60-7.
1997: Stephen F Sells; SS Han; S Muthukkumar; N Maddiwar; R Johnstone; ER Boghaert; D Gillis; G Liu; P Nair; S Monnig; P Collini; Mark P Mattson; Vikas P Sukhatme; Stephen G Zimmer; David P Wood Jr; J William McRoberts; Y Shi; Vivek M Rangnekar
Expression and function of the leucine zipper protein Par-4 in apoptosis.
Molecular and cellular biology 1997;17(7):3823-32.
1997: Inna I Kruman; Annadora J Bruce-Keller; Dale E Bredesen; G Waeg; Mark P Mattson
Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(13):5089-100.
1997: Joe E Springer; Robert D Azbill; RJ Mark; Jim G Begley; G Waeg; Mark P Mattson
4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake.
Journal of neurochemistry 1997;68(6):2469-76.
1997: Qing Guo; Bryce L Sopher; K Furukawa; D G Pham; N Robinson; George M Martin; Mark P Mattson
Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(11):4212-22.
1997: Mark P Mattson; K Furukawa
Alzheimer's disease. Short precursor shortens memory.
Nature 1997;387(6632):457-8.
1997: RJ Mark; Jeff Keller; Inna I Kruman; Mark P Mattson
Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons.
Brain research 1997;756(1-2):205-14.
1997: SM Aziz; Michal J Toborek; B Hennig; Mark P Mattson; H Guo; DW Lipke
Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells.
The international journal of biochemistry & cell biology 1997;29(5):775-87.
1997: Mark P Mattson; RJ Mark; K Furukawa; AJ Bruce
Disruption of brain cell ion homeostasis in Alzheimer's disease by oxy radicals, and signaling pathways that protect therefrom.
Chemical research in toxicology 1997;10(5):507-17.
1997: EM Blanc; Michal J Toborek; RJ Mark; Bernhard Hennig; Mark P Mattson
Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells.
Journal of neurochemistry 1997;68(5):1870-81.
1997: K Furukawa; Steven Estus; W Fu; RJ Mark; Mark P Mattson
Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways.
The Journal of cell biology 1997;136(5):1137-49.
1997: Mark P Mattson
Neuroprotective signal transduction: relevance to stroke.
Neuroscience and biobehavioral reviews 1997;21(2):193-206.
1997: Mark P Mattson; Steven W Barger; K Furukawa; AJ Bruce; Tony Wyss-Coray; RJ Mark; Lennart Mucke
Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease.
Brain research. Brain research reviews 1997;23(1-2):47-61.
1997: RJ Mark; Zhen Pang; James W Geddes; K Uchida; Mark P Mattson
Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(3):1046-54.
1997: Mark P Mattson; K Furukawa
Anti-apoptotic actions of cycloheximide: blockade of programmed cell death or induction of programmed cell life?
Apoptosis : an international journal on programmed cell death 1997;2(3):257-64.
1997: RJ Mark; Mark A Lovell; William R Markesbery; K Uchida; Mark P Mattson
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.
Journal of neurochemistry 1997;68(1):255-64.
1996: Qing Guo; K Furukawa; Bryce L Sopher; D G Pham; J Xie; N Robinson; George M Martin; Mark P Mattson
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.
Neuroreport 1996;8(1):379-83.
1996: C X Xie; Mark P Mattson; Mark A Lovell; Robert A Yokel
Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons.
Brain research 1996;743(1-2):271-7.
1996: Jeff Keller; Marion R Steiner; Mark P Mattson; Sheldon M Steiner
Lysophosphatidic acid decreases glutamate and glucose uptake by astrocytes.
Journal of neurochemistry 1996;67(6):2300-5.
1996: K Furukawa; Bryce L Sopher; Russell E Rydel; Jim G Begley; D G Pham; George M Martin; M Fox; Mark P Mattson
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain.
Journal of neurochemistry 1996;67(5):1882-96.
1996: V L Smith-Swintosky; P J Kraemer; A J Bruce; N McCants; A Maki; R W Brown; M Alcala; Y Goodman; J T Slevin; Mark P Mattson
Bacterial alkaloids mitigate seizure-induced hippocampal damage and spatial memory deficits.
Experimental neurology 1996;141(2):287-96.
1996: Mark P Mattson; R E Rydel
Alzheimer's disease. Amyloid ox-tox transducers.
Nature 1996;382(6593):674-5.
1996: Steven W Barger; Mark P Mattson
Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.
Brain research. Molecular brain research 1996;40(1):116-26.
1996: V L Smith-Swintosky; L Creed Pettigrew; R M Sapolsky; C Phares; S D Craddock; S M Brooke; Mark P Mattson
Metyrapone, an inhibitor of glucocorticoid production, reduces brain injury induced by focal and global ischemia and seizures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):585-98.
1996: A J Bruce; W Boling; Mark S Kindy; J Peschon; P J Kraemer; M K Carpenter; Frederick W Holtsberg; Mark P Mattson
Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors.
Nature medicine 1996;2(7):788-94.
1996: Jeremiah F Kelly; K Furukawa; Steven W Barger; M R Rengen; RJ Mark; EM Blanc; George S Roth; Mark P Mattson
Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6753-8.
1996: Kenneth Hensley; D Allan Butterfield; N Hall; P Cole; R Subramaniam; R Mark; Mark P Mattson; William R Markesbery; M E Harris; Michael Y Aksenov
Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide.
Annals of the New York Academy of Sciences 1996;786():120-34.
1996: RJ Mark; EM Blanc; Mark P Mattson
Amyloid beta-peptide and oxidative cellular injury in Alzheimer's disease.
Molecular neurobiology 1996;12(3):211-24.
1996: Kurt F Hauser; A Stiene-Martin; Mark P Mattson; R P Elde; S E Ryan; C C Godleske
mu-Opioid receptor-induced Ca2+ mobilization and astroglial development: morphine inhibits DNA synthesis and stimulates cellular hypertrophy through a Ca(2+)-dependent mechanism.
Brain research 1996;720(1-2):191-203.
1996: Y Goodman; A J Bruce; B Cheng; Mark P Mattson
Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons.
Journal of neurochemistry 1996;66(5):1836-44.
1996: Mark P Mattson; A J Bruce; EM Blanc
Elusive roles for astrocytes in neurodegenerative disorders.
Neurobiology of aging 1996;17(3):485-7; discussion 488-90.
1996: Douglas G McMahon; Mark P Mattson
Horizontal cell electrical coupling in the giant danio: synaptic modulation by dopamine and synaptic maintenance by calcium.
Brain research 1996;718(1-2):89-96.
1996: B Padmaperuma; R Mark; Harbhajan S Dhillon; Mark P Mattson; MR Prasad
Alterations in brain protein kinase C after experimental brain injury.
Brain research 1996;714(1-2):19-26.
1996: Bernhard Hennig; Michal J Toborek; S Joshi-Barve; Steven W Barger; Shirish Barve; Mark P Mattson; Craig J McClain
Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells.
The American journal of clinical nutrition 1996;63(3):322-8.
1996: Y Goodman; Mark P Mattson
Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity.
Journal of neurochemistry 1996;66(2):869-72.
1996: Steven W Barger; Mark P Mattson
Participation of gene expression in the protection against amyloid beta-peptide toxicity by the beta-amyloid precursor protein.
Annals of the New York Academy of Sciences 1996;777():303-9.
1996: Y Goodman; Mark P Mattson
K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity.
Brain research 1996;706(2):328-32.
1996: K Furukawa; Steven W Barger; Eric M Blalock; Mark P Mattson
Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.
Nature 1996;379(6560):74-8.
1996: Mark P Mattson; K Furukawa
Programmed cell life: anti-apoptotic signaling and therapeutic strategies for neurodegenerative disorders.
Restorative neurology and neuroscience 1996;9(4):191-205.
1996: Mark P Mattson
Human fetal brain cell culture.
Methods in molecular medicine 1996;2():53-62.
1996: Mark P Mattson
Calcium and Free Radicals: Mediators of neurotrophic factor and excitatory transmitter-regulated developmental plasticity and cell death.
Perspectives on developmental neurobiology 1996;3(2):79-91.
1996: Michal J Toborek; Steven W Barger; Mark P Mattson; Shirish Barve; Craig J McClain; Bernhard Hennig
Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells.
Journal of lipid research 1996;37(1):123-35.
1996: Mark P Mattson; RJ Mark
Excitotoxicity and excitoprotection in vitro.
Advances in neurology 1996;71():1-30; discussion 30-5.
1995: B Cheng; K Furukawa; J A O'Keefe; Y Goodman; M Kihiko; T Fabian; Mark P Mattson
Basic fibroblast growth factor selectively increases AMPA-receptor subunit GluR1 protein level and differentially modulates Ca2+ responses to AMPA and NMDA in hippocampal neurons.
Journal of neurochemistry 1995;65(6):2525-36.
1995: Mark P Mattson
Untangling the pathophysiochemistry of beta-amyloid.
Nature structural biology 1995;2(11):926-8.
1995: B Cheng; Mark P Mattson
PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7095-104.
1995: Mark P Mattson; B Cheng; S A Baldwin; V L Smith-Swintosky; Jeff Keller; James W Geddes; Stephen W Scheff; Sylvia Christakos
Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response.
Journal of neuroscience research 1995;42(3):357-70.
1995: Michal J Toborek; Steven W Barger; Mark P Mattson; Craig J McClain; Bernhard Hennig
Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction.
Atherosclerosis 1995;117(2):179-88.
1995: Steven W Barger; Mark P Mattson
The secreted form of the Alzheimer's beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase.
The Biochemical journal 1995;311 ( Pt 1)():45-7.
1995: Mark P Mattson; Mark A Lovell; K Furukawa; William R Markesbery
Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons.
Journal of neurochemistry 1995;65(4):1740-51.
1995: Steven W Barger; D Hörster; K Furukawa; Y Goodman; J Krieglstein; Mark P Mattson
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9328-32.
1995: RJ Mark; Kenneth Hensley; D Allan Butterfield; Mark P Mattson
Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(9):6239-49.
1995: V L Smith-Swintosky; S Zimmer; J W Fenton; Mark P Mattson
Opposing actions of thrombin and protease nexin-1 on amyloid beta-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons.
Journal of neurochemistry 1995;65(3):1415-8.
1995: K Furukawa; Mark P Mattson
Cytochalasins protect hippocampal neurons against amyloid beta-peptide toxicity: evidence that actin depolymerization suppresses Ca2+ influx.
Journal of neurochemistry 1995;65(3):1061-8.
1995: K Furukawa; Mark P Mattson
Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity.
Brain research 1995;689(1):141-6.
1995: Michal J Toborek; Steven W Barger; Mark P Mattson; Parvaneh Espandiari; Larry W Robertson; Bernhard Hennig
Exposure to polychlorinated biphenyls causes endothelial cell dysfunction.
Journal of biochemical toxicology 1995;10(4):219-26.
1995: V L Smith-Swintosky; S Zimmer; J W Fenton; Mark P Mattson
Protease nexin-1 and thrombin modulate neuronal Ca2+ homeostasis and sensitivity to glucose deprivation-induced injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(8):5840-50.
1995: Mark P Mattson
Free radicals and disruption of neuronal ion homeostasis in AD: a role for amyloid beta-peptide?
Neurobiology of aging 1995;16(4):679-82; discussion 683.
1995: K Furukawa; V L Smith-Swintosky; Mark P Mattson
Evidence that actin depolymerization protects hippocampal neurons against excitotoxicity by stabilizing [Ca2+]i.
Experimental neurology 1995;133(2):153-63.
1995: Steven W Barger; R R Fiscus; P Ruth; F Hofmann; Mark P Mattson
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor.
Journal of neurochemistry 1995;64(5):2087-96.
1995: Mark P Mattson
Degenerative and protective signaling mechanisms in the neurofibrillary pathology of AD.
Neurobiology of aging 1995;16(3):447-57; discussion 458-63.
1995: Steven W Barger; Linda Van Eldik; Mark P Mattson
S100 beta protects hippocampal neurons from damage induced by glucose deprivation.
Brain research 1995;677(1):167-70.
1995: Mark P Mattson; Y Goodman
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium.
Brain research 1995;676(1):219-24.
1995: RJ Mark; J Wesson Ashford; Y Goodman; Mark P Mattson
Anticonvulsants attenuate amyloid beta-peptide neurotoxicity, Ca2+ deregulation, and cytoskeletal pathology.
Neurobiology of aging 1995;16(2):187-98.
1995: Mark P Mattson; J W Carney; D Allan Butterfield
A tombstone in Alzheimer's?
Nature 1995;373(6514):481.
1995: Mark P Mattson; Steven W Barger; Jim G Begley; RJ Mark
Calcium, free radicals, and excitotoxic neuronal death in primary cell culture.
Methods in cell biology 1995;46():187-216.
1995: Kenneth Hensley; D Allan Butterfield; Mark P Mattson; Marina V Aksenova; M Harris; J F Wu; R Floyd; J Carney
A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease.
Proceedings of the Western Pharmacology Society 1995;38():113-20.
1994: Mark P Mattson
Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise.
Annals of the New York Academy of Sciences 1994;747():50-76.
1994: B Stein-Behrens; Mark P Mattson; I Chang; M Yeh; R Sapolsky
Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(9):5373-80.
1994: Y Goodman; Marion R Steiner; Sheldon M Steiner; Mark P Mattson
Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation.
Brain research 1994;654(1):171-6.
1994: V L Smith-Swintosky; L Creed Pettigrew; S D Craddock; A R Culwell; Russell E Rydel; Mark P Mattson
Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury.
Journal of neurochemistry 1994;63(2):781-4.
1994: B Cheng; Y Goodman; Jim G Begley; Mark P Mattson
Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury.
Brain research 1994;650(2):331-5.
1994: Y Goodman; Mark P Mattson
Staurosporine and K-252 compounds protect hippocampal neurons against amyloid beta-peptide toxicity and oxidative injury.
Brain research 1994;650(1):170-4.
1994: Y Goodman; Mark P Mattson
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.
Experimental neurology 1994;128(1):1-12.
1994: D Allan Butterfield; Kenneth Hensley; M Harris; Mark P Mattson; J Carney
beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.
Biochemical and biophysical research communications 1994;200(2):710-5.
1994: Kenneth Hensley; JM Carney; Mark P Mattson; Marina V Aksenova; M Harris; J F Wu; R A Floyd; D Allan Butterfield
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3270-4.
1994: Mark P Mattson
Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons.
Journal of neurobiology 1994;25(4):439-50.
1994: B Cheng; Steven W Barger; Mark P Mattson
Staurosporine, K-252a, and K-252b stabilize calcium homeostasis and promote survival of CNS neurons in the absence of glucose.
Journal of neurochemistry 1994;62(4):1319-29.
1994: B Cheng; Mark P Mattson
NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults.
Brain research 1994;640(1-2):56-67.
1994: Mark P Mattson; Stephen W Scheff
Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy.
Journal of neurotrauma 1994;11(1):3-33.
1994: V L Smith-Swintosky; Mark P Mattson
Glutamate, beta-amyloid precursor proteins, and calcium mediated neurofibrillary degeneration.
Journal of neural transmission. Supplementum 1994;44():29-45.
1994: Mark P Mattson
Mechanism of neuronal degeneration and preventative approaches: quickening the pace of AD research.
Neurobiology of aging 1994;15 Suppl 2():S121-5.
1994: B Cheng; S Christakos; Mark P Mattson
Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.
Neuron 1994;12(1):139-53.
1993: A Stiene-Martin; Mark P Mattson; Kurt F Hauser
Opiates selectively increase intracellular calcium in developing type-1 astrocytes: role of calcium in morphine-induced morphologic differentiation.
Brain research. Developmental brain research 1993;76(2):189-96.
1993: Mark P Mattson; B Cheng
Growth factors protect neurons against excitotoxic/ischemic damage by stabilizing calcium homeostasis.
Stroke; a journal of cerebral circulation 1993;24(12 Suppl):I136-40; discussion I144-5.
1993: Mark P Mattson; B Cheng; V L Smith-Swintosky
Mechanisms of neurotrophic factor protection against calcium- and free radical-mediated excitotoxic injury: implications for treating neurodegenerative disorders.
Experimental neurology 1993;124(1):89-95.
1993: Mark P Mattson; Keshava N Kumar; H Wang; B Cheng; Elias K Michaelis
Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(11):4575-88.
1993: Mark P Mattson; Steven W Barger; B Cheng; I Lieberburg; V L Smith-Swintosky; Russell E Rydel
beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.
Trends in neurosciences 1993;16(10):409-14.
1993: Steven W Barger; V L Smith-Swintosky; Russell E Rydel; Mark P Mattson
beta-Amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():158-64.
1993: Mark P Mattson; K J Tomaselli; Russell E Rydel
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.
Brain research 1993;621(1):35-49.
1993: E M Elliott; Mark P Mattson; P Vanderklish; G Lynch; I Chang; R M Sapolsky
Corticosterone exacerbates kainate-induced alterations in hippocampal tau immunoreactivity and spectrin proteolysis in vivo.
Journal of neurochemistry 1993;61(1):57-67.
1993: Mark P Mattson; Russell E Rydel; I Lieberburg; V L Smith-Swintosky
Altered calcium signaling and neuronal injury: stroke and Alzheimer's disease as examples.
Annals of the New York Academy of Sciences 1993;679():1-21.
1993: Mark P Mattson; Y Zhang; S Bose
Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose.
Experimental neurology 1993;121(1):1-13.
1993: Y Zhang; T Tatsuno; JM Carney; Mark P Mattson
Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(3):378-88.
1993: B Cheng; Douglas G McMahon; Mark P Mattson
Modulation of calcium current, intracellular calcium levels and cell survival by glucose deprivation and growth factors in hippocampal neurons.
Brain research 1993;607(1-2):275-85.
1993: Mark P Mattson; B Cheng; A R Culwell; F S Esch; I Lieberburg; Russell E Rydel
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.
Neuron 1993;10(2):243-54.
1993: Mark P Mattson; Mark A Lovell; WD Ehmann; William R Markesbery
Comparison of the effects of elevated intracellular aluminum and calcium levels on neuronal survival and tau immunoreactivity.
Brain research 1993;602(1):21-31.
1993: Mark P Mattson; Steven W Barger
Roles for calcium signaling in structural plasticity and pathology in the hippocampal system.
Hippocampus 1993;3 Spec No():73-87.
1992: Mark P Mattson; Russell E Rydel
beta-Amyloid precursor protein and Alzheimer's disease: the peptide plot thickens.
Neurobiology of aging 1992;13(5):617-21.
1992: B Cheng; Mark P Mattson
Glucose deprivation elicits neurofibrillary tangle-like antigenic changes in hippocampal neurons: prevention by NGF and bFGF.
Experimental neurology 1992;117(2):114-23.
1992: Mark P Mattson
Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons.
Brain research 1992;582(1):107-18.
1992: B Cheng; Mark P Mattson
IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(4):1558-66.
1992: Mark P Mattson; B Rychlik; B Cheng
Degenerative and axon outgrowth-altering effects of phencyclidine in human fetal cerebral cortical cells.
Neuropharmacology 1992;31(3):279-91.
1992: Mark P Mattson; B Cheng; D Davis; K Bryant; I Lieberburg; Russell E Rydel
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(2):376-89.
1992: Mark P Mattson
Calcium as sculptor and destroyer of neural circuitry.
Experimental gerontology 1992;27(1):29-49.
1991: B Cheng; Mark P Mattson
NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis.
Neuron 1991;7(6):1031-41.
1991: Mark P Mattson; H Wang; Elias K Michaelis
Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons.
Brain research 1991;565(1):94-108.
1991: Mark P Mattson; B Rychlik
Comparison of rates of neuronal development and survival in human and rat cerebral cortical cell cultures.
Mechanisms of ageing and development 1991;60(2):171-87.
1991: Mark P Mattson; M G Engle; B Rychlik
Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1991;15(2):117-42.
1991: Mark P Mattson
Activities in cellular signalling pathways: a two-edged sword?
Neurobiology of aging 1991;12(4):343-6; discussion 352-5.
1991: Mark P Mattson
Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons.
Experimental neurology 1991;112(1):95-103.
1991: Mark P Mattson; B Rychlik; J S You; J E Sisken
Sensitivity of cultured human embryonic cerebral cortical neurons to excitatory amino acid-induced calcium influx and neurotoxicity.
Brain research 1991;542(1):97-106.
1991: Mark P Mattson; B Rychlik; C Chu; Sylvia Christakos
Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons.
Neuron 1991;6(1):41-51.
1990: Mark P Mattson; B Rychlik
Cell culture of cryopreserved human fetal cerebral cortical and hippocampal neurons: neuronal development and responses to trophic factors.
Brain research 1990;522(2):204-14.
1990: Mark P Mattson; M Murain; Peter Guthrie
Localized calcium influx orients axon formation in embryonic hippocampal pyramidal neurons.
Brain research. Developmental brain research 1990;52(1-2):201-9.
1990: Mark P Mattson; B Rychlik
Glia protect hippocampal neurons against excitatory amino acid-induced degeneration: involvement of fibroblast growth factor.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1990;8(4):399-415.
1990: Mark P Mattson
Excitatory amino acids, growth factors, and calcium: a teeter-totter model for neural plasticity and degeneration.
Advances in experimental medicine and biology 1990;268():211-20.
1990: Mark P Mattson
Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2+ influx in cultured hippocampal neurons.
Neuron 1990;4(1):105-17.
1989: Mark P Mattson; M Murrain; Peter Guthrie; S B Kater
Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(11):3728-40.
1989: Mark P Mattson; Peter Guthrie; S B Kater
A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(13):2519-26.
1989: Mark P Mattson
Cellular signaling mechanisms common to the development and degeneration of neuroarchitecture. A review.
Mechanisms of ageing and development 1989;50(2):103-57.
1989: Milo C Wiltbank; Peter Guthrie; Mark P Mattson; SB Kater; Gordon D Niswender
Hormonal regulation of free intracellular calcium concentrations in small and large ovine luteal cells.
Biology of reproduction 1989;41(4):771-8.
1989: Mark P Mattson
Acetylcholine potentiates glutamate-induced neurodegeneration in cultured hippocampal neurons.
Brain research 1989;497(2):402-6.
1989: Mark P Mattson; SB Kater
Development and selective neurodegeneration in cell cultures from different hippocampal regions.
Brain research 1989;490(1):110-25.
1989: Mark P Mattson; Peter Guthrie; B C Hayes; SB Kater
Roles for mitotic history in the generation and degeneration of hippocampal neuroarchitecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(4):1223-32.
1989: Mark P Mattson; SB Kater
Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture.
Brain research 1989;478(2):337-48.
1989: Mark P Mattson; Peter Guthrie; SB Kater
Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons.
Progress in clinical and biological research 1989;317():333-51.
1989: S B Kater; Mark P Mattson; Peter Guthrie
Calcium-induced neuronal degeneration: a normal growth cone regulating signal gone awry (?).
Annals of the New York Academy of Sciences 1989;568():252-61.
1988: Mark P Mattson; R E Lee; Marvin Adams; Peter Guthrie; SB Kater
Interactions between entorhinal axons and target hippocampal neurons: a role for glutamate in the development of hippocampal circuitry.
Neuron 1988;1(9):865-76.
1988: Mark P Mattson; Peter Guthrie; SB Kater
Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture.
Journal of neuroscience research 1988;21(2-4):447-64.
1988: Mark P Mattson; Peter Guthrie; SB Kater
Components of neurite outgrowth that determine neuronal cytoarchitecture: influence of calcium and the growth substrate.
Journal of neuroscience research 1988;20(3):331-45.
1988: S B Kater; Mark P Mattson; C Cohan; J Connor
Calcium regulation of the neuronal growth cone.
Trends in neurosciences 1988;11(7):315-21.
1988: Mark P Mattson; Ping Dou; SB Kater
Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(6):2087-100.
1988: Mark P Mattson; A Taylor-Hunter; SB Kater
Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(5):1704-11.
1988: Mark P Mattson; SB Kater
Fibronectin-like immunoreactivity in Helisoma buccal ganglia: evidence that an endogenous fibronectin-like molecule promotes neurite outgrowth.
Journal of neurobiology 1988;19(3):239-56.
1988: Mark P Mattson
Neurotransmitters in the regulation of neuronal cytoarchitecture.
Brain research 1988;472(2):179-212.
1988: Mark P Mattson; SB Kater
Isolated hippocampal neurons in cryopreserved long-term cultures: development of neuroarchitecture and sensitivity to NMDA.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1988;6(5):439-52.
1987: Mark P Mattson; SB Kater
Calcium regulation of neurite elongation and growth cone motility.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(12):4034-43.
1987: Mark P Mattson; E Spaziani
Demonstration of protein kinase C activity in crustacean Y-organs, and partial definition of its role in regulation of ecdysteroidogenesis.
Molecular and cellular endocrinology 1987;49(2-3):159-71.
1986: Mark P Mattson; E Spaziani
Regulation of crab Y-organ steroidogenesis in vitro: evidence that ecdysteroid production increases through activation of cAMP-phosphodiesterase by calcium-calmodulin.
Molecular and cellular endocrinology 1986;48(2-3):135-51.
1986: Mark P Mattson; E Spaziani
Regulation of Y-organ ecdysteroidogenesis by molt-inhibiting hormone in crabs: involvement of cyclic AMP-mediated protein synthesis.
General and comparative endocrinology 1986;63(3):414-23.
1986: Mark P Mattson; E Spaziani
Regulation of the stress-responsive X-organ--Y-organ axis by 5-hydroxytryptamine in the crab, Cancer antennarius.
General and comparative endocrinology 1986;62(3):419-27.
1985: Mark P Mattson; E Spaziani
Characterization of molt-inhibiting hormone (MIH) action on crustacean Y-organ segments and dispersed cells in culture and a bioassay for MIH activity.
The Journal of experimental zoology 1985;236(1):93-101.
1985: Mark P Mattson; E Spaziani
Cyclic AMP mediates the negative regulation of Y-organ ecdysteroid production.
Molecular and cellular endocrinology 1985;42(2):185-9.
1985: Mark P Mattson; J J Mrotek
Exogenous steroids alter steroidogenesis in cultured Y-1 adrenal tumor cells by actions preceding cyclic AMP.
Steroids 1985;46(1):619-37.
1985: Mark P Mattson; E Spaziani
Functional relations of crab molt-inhibiting hormone and neurohypophysial peptides.
Peptides 1985;6(4):635-40.
1985: Mark P Mattson; E Spaziani
Stress reduces hemolymph ecdysteroid levels in the crab: mediation by the eyestalks.
The Journal of experimental zoology 1985;234(2):319-23.