Mark Mattson

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TOP 3
Weissman Lior; de Souza-Pinto Nadja C; Mattson Mark P; Bohr Vilhelm A
DNA base excision repair activities in mouse models of Alzheimer's disease.
Zhang Peisu; Lathia Justin D; Flavahan William A; Rich Jeremy N; Mattson Mark P
Squelching glioblastoma stem cells by targeting REST for proteasomal degradation.
Mattson Mark P
Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.

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All Publications

2009: Weissman Lior; de Souza-Pinto Nadja C; Mattson Mark P; Bohr Vilhelm A
DNA base excision repair activities in mouse models of Alzheimer's disease.
Neurobiology of aging 2009;30(12):2080-1.
2009: Zhang Peisu; Lathia Justin D; Flavahan William A; Rich Jeremy N; Mattson Mark P
Squelching glioblastoma stem cells by targeting REST for proteasomal degradation.
Trends in neurosciences 2009;32(11):559-65.
2009: Mattson Mark P
Roles of the lipid peroxidation product 4-hydroxynonenal in obesity, the metabolic syndrome, and associated vascular and neurodegenerative disorders.
Experimental gerontology 2009;44(10):625-33.
2009: Stranahan Alexis M; Lee Kim; Martin Bronwen; Maudsley Stuart; Golden Erin; Cutler Roy G; Mattson Mark P
Voluntary exercise and caloric restriction enhance hippocampal dendritic spine density and BDNF levels in diabetic mice.
Hippocampus 2009;19(10):951-61.
2009: Loulier Karine; Lathia Justin D; Marthiens Veronique; Relucio Jenne; Mughal Mohamed R; Tang Sung-Chun; Coksaygan Turhan; Hall Peter E; Chigurupati Srinivasulu; Patton Bruce; Colognato Holly; Rao Mahendra S; Mattson Mark P; Haydar Tarik F; Ffrench-Constant Charles
beta1 integrin maintains integrity of the embryonic neocortical stem cell niche.
PLoS biology 2009;7(8):e1000176.
2009: Xue Haipeng; Wu Sen; Papadeas Sophia T; Spusta Steve; Swistowska Anna Maria; MacArthur Chad C; Mattson Mark P; Maragakis Nicholas J; Capecchi Mario R; Rao Mahendra S; Zeng Xianmin; Liu Ying
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells.
Stem cells (Dayton, Ohio) 2009;27(8):1836-46.
2009: Gautheron Vanessa; Auffret Alexandra; Mattson Mark P; Mariani Jean; Vernet-der Garabedian Béatrice
A new and simple approach for genotyping Alzheimer's disease presenilin-1 mutant knock-in mice.
Journal of neuroscience methods 2009;181(2):235-40.
2009: Okun Eitan; Lathia Justin D; Mattson Mark P
Adhesion- and migration-related side effects of phosphothioated CpG oligodeoxynucleotides.
Cell adhesion & migration 2009;3(3):272-4.
2009: Wu Fangbai; Matsuoka Yasuji; Mattson Mark P; Yao Pamela J
The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide.
Biochemical and biophysical research communications 2009;385(2):247-50.
2009: Wang Yue; Greig Nigel H; Yu Qian-sheng; Mattson Mark P
Presenilin-1 mutation impairs cholinergic modulation of synaptic plasticity and suppresses NMDA currents in hippocampus slices.
Neurobiology of aging 2009;30(7):1061-8.
2009: Wheeler David; Knapp Edward; Bandaru Veera V R; Wang Yue; Knorr David; Poirier Christophe; Mattson Mark P; Geiger Jonathan D; Haughey Norman J
Tumor necrosis factor-alpha-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors.
Journal of neurochemistry 2009;109(5):1237-49.
2009: Lu C B; Fu W; Xu X; Mattson M P
Numb-mediated neurite outgrowth is isoform-dependent, and requires activation of voltage-dependent calcium channels.
Neuroscience 2009;161(2):403-12.
2009: Okun Eitan; Mattson Mark P
Phosphothioated oligodeoxynucleotides induce nonspecific effects on neuronal cell adhesion in a growth substrate-dependent manner.
Journal of neuroscience research 2009;87(8):1947-52.
2009: Mattson Mark P; Maudsley Stuart
Live longer sans the AT1A receptor.
Cell metabolism 2009;9(5):403-5.
2009: Gleichmann Marc; Collis Leon P; Smith Peter J S; Mattson Mark P
Simultaneous single neuron recording of O2 consumption, [Ca2+]i and mitochondrial membrane potential in glutamate toxicity.
Journal of neurochemistry 2009;109(2):644-55.
2009: Giliberto Luca; Borghi Roberta; Piccini Alessandra; Mangerini Rosa; Sorbi Sandro; Cirmena Gabriella; Garuti Anna; Ghetti Bernardino; Tagliavini Fabrizio; Mughal Mohamed R; Mattson Mark P; Zhu Xiongwei; Wang Xinglong; Guglielmotto Michela; Tamagno Elena; Tabaton Massimo
Mutant presenilin 1 increases the expression and activity of BACE1.
The Journal of biological chemistry 2009;284(14):9027-38.
2009: Maalouf Marwan; Rho Jong M; Mattson Mark P
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies.
Brain research reviews 2009;59(2):293-315.
2009: Okun Eitan; Griffioen Kathleen J; Lathia Justin D; Tang Sung-Chun; Mattson Mark P; Arumugam Thiruma V
Toll-like receptors in neurodegeneration.
Brain research reviews 2009;59(2):278-92.
2009: Gulyani Seema; Earley Christopher J; Camandola Simonetta; Maudsley Stuart; Ferré Sergi; Mughal Mohamed R; Martin Bronwen; Cheng Aiwu; Gleichmann Marc; Jones Byron C; Allen Richard P; Mattson Mark P
Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells.
Experimental neurology 2009;215(2):236-42.
2009: Martin Bronwen; Golden Erin; Carlson Olga D; Pistell Paul; Zhou Jie; Kim Wook; Frank Brittany P; Thomas Sam; Chadwick Wayne A; Greig Nigel H; Bates Gillian P; Sathasivam Kirupa; Bernier Michel; Maudsley Stuart; Mattson Mark P; Egan Josephine M
Exendin-4 improves glycemic control, ameliorates brain and pancreatic pathologies, and extends survival in a mouse model of Huntington's disease.
Diabetes 2009;58(2):318-28.
2009: Arumugam T V; Woodruff T M; Lathia J D; Selvaraj P K; Mattson M P; Taylor S M
Neuroprotection in stroke by complement inhibition and immunoglobulin therapy.
Neuroscience 2009;158(3):1074-89.
2009: Li Yazhou; Perry TracyAnn; Kindy Mark S; Harvey Brandon K; Tweedie David; Holloway Harold W; Powers Kathleen; Shen Hui; Egan Josephine M; Sambamurti Kumar; Brossi Arnold; Lahiri Debomoy K; Mattson Mark P; Hoffer Barry J; Wang Yun; Greig Nigel H
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1285-90.
2009: Mattson Mark P; Ashery Uri
No more brain tangles with DeltaNp73.
Trends in biochemical sciences 2009;34(1):6-8.
2009: Hutchison Emmette R; Okun Eitan; Mattson Mark P
The therapeutic potential of microRNAs in nervous system damage, degeneration, and repair.
Neuromolecular medicine 2009;11(3):153-61.
2009: Varma R; Chai Y; Troncoso J; Gu J; Xing H; Stojilkovic S S; Mattson M P; Haughey N J
Amyloid-beta induces a caspase-mediated cleavage of P2X4 to promote purinotoxicity.
Neuromolecular medicine 2009;11(2):63-75.
2009: Tavakoli Tahereh; Xu Xiangru; Derby Eric; Serebryakova Yevgeniya; Reid Yvonne; Rao Mahendra S; Mattson Mark P; Ma Wu
Self-renewal and differentiation capabilities are variable between human embryonic stem cell lines I3, I6 and BG01V.
BMC cell biology 2009;10():44.
2009: Bruestle Daniel A; Cutler Roy G; Telljohann Richard S; Mattson Mark P
Decline in daily running distance presages disease onset in a mouse model of ALS.
Neuromolecular medicine 2009;11(2):58-62.
2009: Liu Dong; Gharavi Robert; Pitta Michael; Gleichmann Marc; Mattson Mark P
Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons.
Neuromolecular medicine 2009;11(1):28-42.
2009: Martin Bronwen; Pearson Michele; Brenneman Randall; Golden Erin; Wood William; Prabhu Vinayakumar; Becker Kevin G; Mattson Mark P; Maudsley Stuart
Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment.
PloS one 2009;4(1):e4146.
2008: Lathia Justin D; Mattson Mark P; Cheng Aiwu
Notch: from neural development to neurological disorders.
Journal of neurochemistry 2008;107(6):1471-81.
2008: Lathia Justin D; Okun Eitan; Tang Sung-Chun; Griffioen Kathleen; Cheng Aiwu; Mughal Mohamed R; Laryea Gloria; Selvaraj Pradeep K; ffrench-Constant Charles; Magnus Tim; Arumugam Thiruma V; Mattson Mark P
Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(51):13978-84.
2008: Mattson Mark P; Gleichmann Marc; Cheng Aiwu
Mitochondria in neuroplasticity and neurological disorders.
Neuron 2008;60(5):748-66.
2008: Liu Dong; Pitta Michael; Mattson Mark P
Preventing NAD(+) depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction.
Annals of the New York Academy of Sciences 2008;1147():275-82.
2008: Mattson Mark P
Glutamate and neurotrophic factors in neuronal plasticity and disease.
Annals of the New York Academy of Sciences 2008;1144():97-112.
2008: Chigurupati Srinivasulu; Son Tae Gen; Hyun Dong-Hoon; Lathia Justin D; Mughal Mohamed R; Savell Jason; Li Shuan C; Nagaraju G P C; Chan Sic L; Arumugam Thiruma V; Mattson Mark P
Lifelong running reduces oxidative stress and degenerative changes in the testes of mice.
The Journal of endocrinology 2008;199(2):333-41.
2008: Szklarczyk Arek; Ewaleifoh Osefame; Beique Jean-Claude; Wang Yue; Knorr David; Haughey Norman; Malpica Tanya; Mattson Mark P; Huganir Richard; Conant Katherine
MMP-7 cleaves the NR1 NMDA receptor subunit and modifies NMDA receptor function.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(11):3757-67.
2008: Bushlin Ittai; Petralia Ronald S; Wu Fangbai; Harel Asaff; Mughal Mohamed R; Mattson Mark P; Yao Pamela J
Clathrin assembly protein AP180 and CALM differentially control axogenesis and dendrite outgrowth in embryonic hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(41):10257-71.
2008: Zhang Peisu; Pazin Michael J; Schwartz Catherine M; Becker Kevin G; Wersto Robert P; Dilley Caroline M; Mattson Mark P
Nontelomeric TRF2-REST interaction modulates neuronal gene silencing and fate of tumor and stem cells.
Current biology : CB 2008;18(19):1489-94.
2008: Chadwick Wayne; Magnus Tim; Martin Bronwen; Keselman Aleksander; Mattson Mark P; Maudsley Stuart
Targeting TNF-alpha receptors for neurotherapeutics.
Trends in neurosciences 2008;31(10):504-11.
2008: Nagababu Enika; Gulyani Seema; Earley Christopher J; Cutler Roy G; Mattson Mark P; Rifkind Joseph M
Iron-deficiency anaemia enhances red blood cell oxidative stress.
Free radical research 2008;42(9):824-9.
2008: Kulkarni Avanti; McNeill Daniel R; Gleichmann Marc; Mattson Mark P; Wilson David M
XRCC1 protects against the lethality of induced oxidative DNA damage in nondividing neural cells.
Nucleic acids research 2008;36(15):5111-21.
2008: Bezprozvanny Ilya; Mattson Mark P
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease.
Trends in neurosciences 2008;31(9):454-63.
2008: Luo Yongquan; Lathia Justin; Mughal Mohammed; Mattson Mark P
SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons.
The Journal of biological chemistry 2008;283(36):24789-800.
2008: Kyriazis George A; Wei Zelan; Vandermey Miriam; Jo Dong-Gyu; Xin Ouyang; Mattson Mark P; Chan Sic L
Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis.
The Journal of biological chemistry 2008;283(37):25492-502.
2008: Tang Sung-Chun; Lathia Justin D; Selvaraj Pradeep K; Jo Dong-Gyu; Mughal Mohamed R; Cheng Aiwu; Siler Dominic A; Markesbery William R; Arumugam Thiruma V; Mattson Mark P
Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal.
Experimental neurology 2008;213(1):114-21.
2008: Stranahan Alexis M; Lee Kim; Pistell Paul J; Nelson Christopher M; Readal Nathaniel; Miller Marshall G; Spangler Edward L; Ingram Donald K; Mattson Mark P
Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels.
Neurobiology of learning and memory 2008;90(2):479-83.
2008: Wang Wang; Fang Huaqiang; Groom Linda; Cheng Aiwu; Zhang Wanrui; Liu Jie; Wang Xianhua; Li Kaitao; Han Peidong; Zheng Ming; Yin Jinhu; Wang Weidong; Mattson Mark P; Kao Joseph P Y; Lakatta Edward G; Sheu Shey-Shing; Ouyang Kunfu; Chen Ju; Dirksen Robert T; Cheng Heping
Superoxide flashes in single mitochondria.
Cell 2008;134(2):279-90.
2008: Yang Jenq-Lin; Weissman Lior; Bohr Vilhelm A; Mattson Mark P
Mitochondrial DNA damage and repair in neurodegenerative disorders.
DNA repair 2008;7(7):1110-20.
2008: Shin Yu-Kyong; Martin Bronwen; Golden Erin; Dotson Cedrick D; Maudsley Stuart; Kim Wook; Jang Hyeung-Jin; Mattson Mark P; Drucker Daniel J; Egan Josephine M; Munger Steven D
Modulation of taste sensitivity by GLP-1 signaling.
Journal of neurochemistry 2008;106(1):455-63.
2008: Liu Manchang; Liang Yideng; Chigurupati Srinivasulu; Lathia Justin D; Pletnikov Mikhail; Sun Zhaoli; Crow Michael; Ross Christopher A; Mattson Mark P; Rabb Hamid
Acute kidney injury leads to inflammation and functional changes in the brain.
Journal of the American Society of Nephrology : JASN 2008;19(7):1360-70.
2008: Martin Bronwen; Golden Erin; Carlson Olga D; Egan Josephine M; Mattson Mark P; Maudsley Stuart
Caloric restriction: impact upon pituitary function and reproduction.
Ageing research reviews 2008;7(3):209-24.
2008: Stranahan Alexis M; Lee Kim; Mattson Mark P
Contributions of impaired hippocampal plasticity and neurodegeneration to age-related deficits in hormonal pulsatility.
Ageing research reviews 2008;7(3):164-76.
2008: Hirata-Fukae Chiho; Li Hui-Fang; Hoe Hyang-Sook; Gray Audrey J; Minami S Sakura; Hamada Katsuyoshi; Niikura Takako; Hua Fang; Tsukagoshi-Nagai Hiroe; Horikoshi-Sakuraba Yuko; Mughal Mohamed; Rebeck G William; LaFerla Frank M; Mattson Mark P; Iwata Nobuhisa; Saido Takaomi C; Klein William L; Duff Karen E; Aisen Paul S; Matsuoka Yasuji
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.
Brain research 2008;1216():92-103.
2008: Kim So Jung; Son Tae Gen; Park Hee Ra; Park Mikyung; Kim Min-Sun; Kim Hyung Sik; Chung Hae Young; Mattson Mark P; Lee Jaewon
Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus.
The Journal of biological chemistry 2008;283(21):14497-505.
2008: Yamada Yuko; Tian Jane; Yang Yanqin; Cutler Roy G; Wu Tinghuai; Telljohann Richard S; Mattson Mark P; Handa James T
Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells.
Journal of neurochemistry 2008;105(4):1187-97.
2008: Juhaszova Magdalena; Wang Su; Zorov Dmitry B; Nuss H Bradley; Gleichmann Marc; Mattson Mark P; Sollott Steven J
The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown.
Annals of the New York Academy of Sciences 2008;1123():197-212.
2008: Mattson Mark P; van Praag Henriette
TAGing APP constrains neurogenesis.
Nature cell biology 2008;10(3):249-50.
2008: Stranahan Alexis M; Arumugam Thiruma V; Cutler Roy G; Lee Kim; Egan Josephine M; Mattson Mark P
Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons.
Nature neuroscience 2008;11(3):309-17.
2008: Harel Asaff; Wu Fangbai; Mattson Mark P; Morris Christa M; Yao Pamela J
Evidence for CALM in directing VAMP2 trafficking.
Traffic (Copenhagen, Denmark) 2008;9(3):417-29.
2008: Kawamoto E M; Lepsch L B; Boaventura M F C; Munhoz C D; Lima L S; Yshii L M; Avellar M C W; Curi R; Mattson M P; Scavone C
Amyloid beta-peptide activates nuclear factor-kappaB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells.
Journal of neuroscience research 2008;86(4):845-60.
2008: Mattson Mark P
Hormesis and disease resistance: activation of cellular stress response pathways.
Human & experimental toxicology 2008;27(2):155-62.
2008: Tamagno Elena; Guglielmotto Michela; Aragno Manuela; Borghi Roberta; Autelli Riccardo; Giliberto Luca; Muraca Giuseppe; Danni Oliviero; Zhu Xiongwei; Smith Mark A; Perry George; Jo Dong-Gyu; Mattson Mark P; Tabaton Massimo
Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein.
Journal of neurochemistry 2008;104(3):683-95.
2008: Martin Bronwen; Golden Erin; Keselman Alex; Stone Matthew; Mattson Mark P; Egan Josephine M; Maudsley Stuart
Therapeutic perspectives for the treatment of Huntington's disease: treating the whole body.
Histology and histopathology 2008;23(2):237-50.
2008: Mattson Mark P
Hormesis defined.
Ageing research reviews 2008;7(1):1-7.
2008: Arumugam Thiruma V; Selvaraj Pradeep K; Woodruff Trent M; Mattson Mark P
Targeting ischemic brain injury with intravenous immunoglobulin.
Expert opinion on therapeutic targets 2008;12(1):19-29.
2008: Magnus Tim; Carmen Jessica; Deleon Jessica; Xue Haipeng; Pardo Andrea C; Lepore Angelo C; Mattson Mark P; Rao Mahendra S; Maragakis Nicholas J
Adult glial precursor proliferation in mutant SOD1G93A mice.
Glia 2008;56(2):200-8.
2008: Guo Zhihong; Jiang Haiyang; Xu Xiangru; Duan Wenzhen; Mattson Mark P
Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization.
The Journal of biological chemistry 2008;283(3):1754-63.
2008: Mattson Mark P
Dietary factors, hormesis and health.
Ageing research reviews 2008;7(1):43-8.
2008: Sun Yu; Li Huai; Liu Ying; Mattson Mark P; Rao Mahendra S; Zhan Ming
Evolutionarily conserved transcriptional co-expression guiding embryonic stem cell differentiation.
PloS one 2008;3(10):e3406.
2008: Ma Wu; Tavakoli Tara; Derby Eric; Serebryakova Yevgeniya; Rao Mahendra S; Mattson Mark P
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells.
BMC developmental biology 2008;8():90.
2008: Mattson Mark P
Awareness of hormesis will enhance future research in basic and applied neuroscience.
Critical reviews in toxicology 2008;38(7):633-9.
2008: Stranahan Alexis M; Norman Eric D; Lee Kim; Cutler Roy G; Telljohann Richard S; Egan Josephine M; Mattson Mark P
Diet-induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle-aged rats.
Hippocampus 2008;18(11):1085-8.
2008: Martin Bronwen; Pearson Michele; Brenneman Randall; Golden Erin; Keselman Alex; Iyun Titilola; Carlson Olga D; Egan Josephine M; Becker Kevin G; Wood William; Prabhu Vinayakumar; de Cabo Rafael; Maudsley Stuart; Mattson Mark P
Conserved and differential effects of dietary energy intake on the hippocampal transcriptomes of females and males.
PloS one 2008;3(6):e2398.
2008: Son Tae Gen; Camandola Simonetta; Mattson Mark P
Hormetic dietary phytochemicals.
Neuromolecular medicine 2008;10(4):236-46.
2008: Stranahan Alexis M; Mattson Mark P
Impact of energy intake and expenditure on neuronal plasticity.
Neuromolecular medicine 2008;10(4):209-18.
2008: Mattson Mark P; Zhang Peisu; Cheng Aiwu
Telomere neurobiology.
Methods in molecular biology (Clifton, N.J.) 2008;438():185-96.
2008: Stranahan Alexis M; Lee Kim; Mattson Mark P
Central mechanisms of HPA axis regulation by voluntary exercise.
Neuromolecular medicine 2008;10(2):118-27.
2008: Wang Yue; Chandran Jayanth S; Cai Huaibin; Mattson Mark P
DJ-1 is essential for long-term depression at hippocampal CA1 synapses.
Neuromolecular medicine 2008;10(1):40-5.
2008: Mattson Mark P; Wan Ruiqian
Neurotrophic factors in autonomic nervous system plasticity and dysfunction.
Neuromolecular medicine 2008;10(3):157-68.
2007: Carlson Olga; Martin Bronwen; Stote Kim S; Golden Erin; Maudsley Stuart; Najjar Samer S; Ferrucci Luigi; Ingram Donald K; Longo Dan L; Rumpler William V; Baer David J; Egan Josephine; Mattson Mark P
Impact of reduced meal frequency without caloric restriction on glucose regulation in healthy, normal-weight middle-aged men and women.
Metabolism: clinical and experimental 2007;56(12):1729-34.
2007: Lathia Justin D; Patton Bruce; Eckley D Mark; Magnus Tim; Mughal Mohamed R; Sasaki Takako; Caldwell Maeve A; Rao Mahendra S; Mattson Mark P; ffrench-Constant Charles
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.
The Journal of comparative neurology 2007;505(6):630-43.
2007: Lathia Justin D; Rao Mahendra S; Mattson Mark P; Ffrench-Constant Charles
The microenvironment of the embryonic neural stem cell: lessons from adult niches?
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(12):3267-82.
2007: Zahn Jacob M; Poosala Suresh; Owen Art B; Ingram Donald K; Lustig Ana; Carter Arnell; Weeraratna Ashani T; Taub Dennis D; Gorospe Myriam; Mazan-Mamczarz Krystyna; Lakatta Edward G; Boheler Kenneth R; Xu Xiangru; Mattson Mark P; Falco Geppino; Ko Minoru S H; Schlessinger David; Firman Jeffrey; Kummerfeld Sarah K; Wood William H; Zonderman Alan B; Kim Stuart K; Becker Kevin G
AGEMAP: a gene expression database for aging in mice.
PLoS genetics 2007;3(11):e201.
2007: Takata Kazuyuki; Hirata-Fukae Chiho; Becker Amanda G; Chishiro Saori; Gray Audrey J; Nishitomi Kouhei; Franz Andreas H; Sakaguchi Gaku; Kato Akira; Mattson Mark P; Laferla Frank M; Aisen Paul S; Kitamura Yoshihisa; Matsuoka Yasuji
Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration.
The European journal of neuroscience 2007;26(9):2458-68.
2007: Cherubini Antonio; Andres-Lacueva Cristina; Martin Antonio; Lauretani Fulvio; Iorio Angelo Di; Bartali Benedetta; Corsi Annamaria; Bandinelli Stefania; Mattson Mark P; Ferrucci Luigi
Low plasma N-3 fatty acids and dementia in older persons: the InCHIANTI study.
The journals of gerontology. Series A, Biological sciences and medical sciences 2007;62(10):1120-6.
2007: Martin Bronwen; Pearson Michele; Kebejian Lisa; Golden Erin; Keselman Alex; Bender Meredith; Carlson Olga; Egan Josephine; Ladenheim Bruce; Cadet Jean-Lud; Becker Kevin G; Wood William; Duffy Kara; Vinayakumar Prabhu; Maudsley Stuart; Mattson Mark P
Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess.
Endocrinology 2007;148(9):4318-33.
2007: Arumugam Thiruma V; Tang Sung-Chun; Lathia Justin D; Cheng Aiwu; Mughal Mohamed R; Chigurupati Srinivasulu; Magnus Tim; Chan Sic L; Jo Dong-Gyu; Ouyang Xin; Fairlie David P; Granger Daniel N; Vortmeyer Alexander; Basta Milan; Mattson Mark P
Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(35):14104-9.
2007: Tang Sung-Chun; Arumugam Thiruma V; Xu Xiangru; Cheng Aiwu; Mughal Mohamed R; Jo Dong Gyu; Lathia Justin D; Siler Dominic A; Chigurupati Srinivasulu; Ouyang Xin; Magnus Tim; Camandola Simonetta; Mattson Mark P
Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(34):13798-803.
2007: Luo Yongquan; Xue Haipeng; Pardo Andrea C; Mattson Mark P; Rao Mahendra S; Maragakis Nicholas J
Impaired SDF1/CXCR4 signaling in glial progenitors derived from SOD1(G93A) mice.
Journal of neuroscience research 2007;85(11):2422-32.
2007: Okun Eitan; Arumugam Thiruma V; Tang Sung-Chun; Gleichmann Marc; Albeck Michael; Sredni Benjamin; Mattson Mark P
The organotellurium compound ammonium trichloro(dioxoethylene-0,0') tellurate enhances neuronal survival and improves functional outcome in an ischemic stroke model in mice.
Journal of neurochemistry 2007;102(4):1232-41.
2007: Magnus Tim; Coksaygan Turhan; Korn Thomas; Xue Haipeng; Arumugam Thiruma V; Mughal Mohamed R; Eckley D Mark; Tang Sung-Chun; Detolla Louis; Rao Mahendra S; Cassiani-Ingoni Riccardo; Mattson Mark P
Evidence that nucleocytoplasmic Olig2 translocation mediates brain-injury-induced differentiation of glial precursors to astrocytes.
Journal of neuroscience research 2007;85(10):2126-37.
2007: Kim So Jung; Son Tae Gen; Kim Keunho; Park Hee Ra; Mattson Mark P; Lee Jaewon
Interferon-gamma promotes differentiation of neural progenitor cells via the JNK pathway.
Neurochemical research 2007;32(8):1399-406.
2007: Cassiani-Ingoni Riccardo; Muraro Paolo A; Magnus Tim; Reichert-Scrivner Susan; Schmidt Jens; Huh Jaebong; Quandt Jacqueline A; Bratincsak Andras; Shahar Tal; Eusebi Fabrizio; Sherman Larry S; Mattson Mark P; Martin Roland; Rao Mahendra S
Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response.
Journal of neuropathology and experimental neurology 2007;66(7):637-49.
2007: Calabrese Edward J; Bachmann Kenneth A; Bailer A John; Bolger P Michael; Borak Jonathan; Cai Lu; Cedergreen Nina; Cherian M George; Chiueh Chuang C; Clarkson Thomas W; Cook Ralph R; Diamond David M; Doolittle David J; Dorato Michael A; Duke Stephen O; Feinendegen Ludwig; Gardner Donald E; Hart Ronald W; Hastings Kenneth L; Hayes A Wallace; Hoffmann George R; Ives John A; Jaworowski Zbigniew; Johnson Thomas E; Jonas Wayne B; Kaminski Norbert E; Keller John G; Klaunig James E; Knudsen Thomas B; Kozumbo Walter J; Lettieri Teresa; Liu Shu-Zheng; Maisseu Andre; Maynard Kenneth I; Masoro Edward J; McClellan Roger O; Mehendale Harihara M; Mothersill Carmel; Newlin David B; Nigg Herbert N; Oehme Frederick W; Phalen Robert F; Philbert Martin A; Rattan Suresh I S; Riviere Jim E; Rodricks Joseph; Sapolsky Robert M; Scott Bobby R; Seymour Colin; Sinclair David A; Smith-Sonneborn Joan; Snow Elizabeth T; Spear Linda; Stevenson Donald E; Thomas Yolene; Tubiana Maurice; Williams Gary M; Mattson Mark P
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework.
Toxicology and applied pharmacology 2007;222(1):122-8.
2007: Carmen Jessica; Magnus Tim; Cassiani-Ingoni Riccardo; Sherman Larry; Rao Mahendra S; Mattson Mark P
Revisiting the astrocyte-oligodendrocyte relationship in the adult CNS.
Progress in neurobiology 2007;82(3):151-62.
2007: Mattson Mark P
Calcium and neurodegeneration.
Aging cell 2007;6(3):337-50.
2007: Sredni Benjamin; Geffen-Aricha Revital; Duan Wenzhen; Albeck Michael; Shalit Frances; Lander Harry M; Kinor Noa; Sagi Ortal; Albeck Amnon; Yosef Sigal; Brodsky Miri; Sredni-Kenigsbuch Dvora; Sonino Tali; Longo Dan L; Mattson Mark P; Yadid Gal
Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(8):1870-83.
2007: Bandaru V V R; McArthur J C; Sacktor N; Cutler R G; Knapp E L; Mattson M P; Haughey N J
Associative and predictive biomarkers of dementia in HIV-1-infected patients.
Neurology 2007;68(18):1481-7.
2007: Nelson Rhonda L; Guo Zhihong; Halagappa Veerendra Madala; Pearson Michelle; Gray Audrey J; Matsuoka Yasuji; Brown Martin; Martin Bronwen; Iyun Titilola; Maudsley Stuart; Clark Robert F; Mattson Mark P
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice.
Experimental neurology 2007;205(1):166-76.
2007: Tang Sung-Chun; Arumugam Thiruma V; Cutler Roy G; Jo Dong-Gyu; Magnus Tim; Chan Sic L; Mughal Mohamed R; Telljohann Richard S; Nassar Matthew; Ouyang Xin; Calderan Andrea; Ruzza Paolo; Guiotto Andrea; Mattson Mark P
Neuroprotective actions of a histidine analogue in models of ischemic stroke.
Journal of neurochemistry 2007;101(3):729-36.
2007: Stote Kim S; Baer David J; Spears Karen; Paul David R; Harris G Keith; Rumpler William V; Strycula Pilar; Najjar Samer S; Ferrucci Luigi; Ingram Donald K; Longo Dan L; Mattson Mark P
A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.
The American journal of clinical nutrition 2007;85(4):981-8.
2007: Cheng Aiwu; Shin-ya Kazuo; Wan Ruiqian; Tang Sung-chun; Miura Takumi; Tang Hongyang; Khatri Rina; Gleichman Marc; Ouyang Xin; Liu Dong; Park Hae-Rong; Chiang Jeffrey Y; Mattson Mark P
Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(14):3722-33.
2007: Halagappa Veerendra Kumar Madala; Guo Zhihong; Pearson Michelle; Matsuoka Yasuji; Cutler Roy G; Laferla Frank M; Mattson Mark P
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease.
Neurobiology of disease 2007;26(1):212-20.
2007: Zhang P; Dilley C; Mattson M P
DNA damage responses in neural cells: Focus on the telomere.
Neuroscience 2007;145(4):1439-48.
2007: Mattson Mark P
Mitochondrial regulation of neuronal plasticity.
Neurochemical research 2007;32(4-5):707-15.
2007: Johnson James B; Summer Warren; Cutler Roy G; Martin Bronwen; Hyun Dong-Hoon; Dixit Vishwa D; Pearson Michelle; Nassar Matthew; Telljohann Richard; Maudsley Stuart; Carlson Olga; John Sujit; Laub Donald R; Mattson Mark P
Alternate day calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma.
Free radical biology & medicine 2007;42(5):665-74.
2007: Cheng Aiwu; Coksaygan Turhan; Tang Hongyan; Khatri Rina; Balice-Gordon Rita J; Rao Mahendra S; Mattson Mark P
Truncated tyrosine kinase B brain-derived neurotrophic factor receptor directs cortical neural stem cells to a glial cell fate by a novel signaling mechanism.
Journal of neurochemistry 2007;100(6):1515-30.
2007: Hyun Dong-Hoon; Hunt Nicole D; Emerson Scott S; Hernandez Joe O; Mattson Mark P; de Cabo Rafael
Up-regulation of plasma membrane-associated redox activities in neuronal cells lacking functional mitochondria.
Journal of neurochemistry 2007;100(5):1364-74.
2007: Shin Soojung; Xue Haipeng; Mattson Mark P; Rao Mahendra S
Stage-dependent Olig2 expression in motor neurons and oligodendrocytes differentiated from embryonic stem cells.
Stem cells and development 2007;16(1):131-41.
2007: Cheng Aiwu; Arumugam Thiruma V; Liu Dong; Khatri Rina G; Mustafa Khadija; Kwak Seung; Ling Huai-Ping; Gonzales Cathleen; Xin Ouyang; Jo Dong-Gyu; Guo Zhihong; Mark Robert J; Mattson Mark P
Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(7):1519-28.
2007: Camandola Simonetta; Mattson Mark P
NF-kappa B as a therapeutic target in neurodegenerative diseases.
Expert opinion on therapeutic targets 2007;11(2):123-32.
2007: Sánchez-Alavez Manuel; Chan Sic L; Mattson Mark P; Criado José R
Electrophysiological and cerebrovascular effects of the alpha-secretase-derived form of amyloid precursor protein in young and middle-aged rats.
Brain research 2007;1131(1):112-7.
2007: Wilson David M; Mattson Mark P
Neurodegeneration: nicked to death.
Current biology : CB 2007;17(2):R55-8.
2007: Sun Yu; Li Huai; Liu Ying; Shin Soojung; Mattson Mark P; Rao Mahendra S; Zhan Ming
Cross-species transcriptional profiles establish a functional portrait of embryonic stem cells.
Genomics 2007;89(1):22-35.
2007: Mattson Mark P; Son Tae Gen; Camandola Simonetta
Viewpoint: mechanisms of action and therapeutic potential of neurohormetic phytochemicals.
Dose-response : a publication of International Hormesis Society 2007;5(3):174-86.
2007: Chigurupati Srinivasulu; Arumugam Thiruma V; Son Tae Gen; Lathia Justin D; Jameel Shafaq; Mughal Mohamed R; Tang Sung-Chun; Jo Dong-Gyu; Camandola Simonetta; Giunta Marialuisa; Rakova Irina; McDonnell Nazli; Miele Lucio; Mattson Mark P; Poosala Suresh
Involvement of notch signaling in wound healing.
PloS one 2007;2(11):e1167.
2007: Haberman Frank; Tang Sung-Chun; Arumugam Thiruma V; Hyun Dong-Hoon; Yu Qian-Sheng; Cutler Roy G; Guo Zhihong; Holloway Harold W; Greig Nigel H; Mattson Mark P
Soluble neuroprotective antioxidant uric acid analogs ameliorate ischemic brain injury in mice.
Neuromolecular medicine 2007;9(4):315-23.
2007: Xu Xiangru; Zhan Ming; Duan Wenzhen; Prabhu Vinayakumar; Brenneman Randall; Wood William; Firman Jeff; Li Huai; Zhang Peisu; Ibe Carol; Zonderman Alan B; Longo Dan L; Poosala Suresh; Becker Kevin G; Mattson Mark P
Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender.
Genome biology 2007;8(11):R234.
2007: Weissman Lior; Jo Dong-Gyu; Sørensen Martin M; de Souza-Pinto Nadja C; Markesbery William R; Mattson Mark P; Bohr Vilhelm A
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.
Nucleic acids research 2007;35(16):5545-55.
2007: Matsuoka Yasuji; Gray Audrey J; Hirata-Fukae Chiho; Minami S Sakura; Waterhouse Emily Graeme; Mattson Mark P; LaFerla Frank M; Gozes Illana; Aisen Paul S
Intranasal NAP administration reduces accumulation of amyloid peptide and tau hyperphosphorylation in a transgenic mouse model of Alzheimer's disease at early pathological stage.
Journal of molecular neuroscience : MN 2007;31(2):165-70.
2007: Morgan Grant A; Guo Qing; Chan Sic L; Gary Devin S; Osborne Barbara A; Mattson Mark P
Defects of immune regulation in the presenilin-1 mutant knockin mouse.
Neuromolecular medicine 2007;9(1):35-45.
2007: Mattson Mark P; Cutler Roy G; Camandola Simonetta
Energy intake and amyotrophic lateral sclerosis.
Neuromolecular medicine 2007;9(1):17-20.
2007: Marini A M; Jiang X; Wu X; Pan H; Guo Z; Mattson M P; Blondeau N; Novelli A; Lipsky R H
Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli.
Amino acids 2007;32(3):299-304.
2006: Hyun Dong-Hoon; Emerson Scott S; Jo Dong-Gyu; Mattson Mark P; de Cabo Rafael
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(52):19908-12.
2006: Wang Yue; Mackes Jennifer; Chan Stephen; Haughey Norman J; Guo Zhihong; Ouyang Xin; Furukawa Katsutoshi; Ingram Donald K; Mattson Mark P
Impaired long-term depression in P2X3 deficient mice is not associated with a spatial learning deficit.
Journal of neurochemistry 2006;99(5):1425-34.
2006: Chan Sic L; Liu Dong; Kyriazis George A; Bagsiyao Pamela; Ouyang Xin; Mattson Mark P
Mitochondrial uncoupling protein-4 regulates calcium homeostasis and sensitivity to store depletion-induced apoptosis in neural cells.
The Journal of biological chemistry 2006;281(49):37391-403.
2006: Mattson Mark P
Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders.
Antioxidants & redox signaling 2006;8(11-12):1997-2006.
2006: Mattson Mark P; Cheng Aiwu
Neurohormetic phytochemicals: Low-dose toxins that induce adaptive neuronal stress responses.
Trends in neurosciences 2006;29(11):632-9.
2006: Cutler Roy G; Mattson Mark P
The adversities of aging.
Ageing research reviews 2006;5(3):221-38.
2006: Martin Bronwen; Mattson Mark P; Maudsley Stuart
Caloric restriction and intermittent fasting: two potential diets for successful brain aging.
Ageing research reviews 2006;5(3):332-53.
2006: Furay A R; Murphy E K; Mattson M P; Guo Z; Herman J P
Region-specific regulation of glucocorticoid receptor/HSP90 expression and interaction in brain.
Journal of neurochemistry 2006;98(4):1176-84.
2006: Walker Lary C; Levine Harry; Mattson Mark P; Jucker Mathias
Inducible proteopathies.
Trends in neurosciences 2006;29(8):438-43.
2006: Mattson Mark P
Nitro-PDI incites toxic waste accumulation.
Nature neuroscience 2006;9(7):865-7.
2006: Turchan-Cholewo Jadwiga; Liu Yiling; Gartner Suzanne; Reid Rollie; Jie Chunfa; Peng Xuejun; Chen Kuey Chu C; Chauhan Ashok; Haughey Norman; Cutler Roy; Mattson Mark P; Pardo Carlos; Conant Katherine; Sacktor Ned; McArthur Justin C; Hauser Kurt F; Gairola Chandra; Nath Avindra
Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: protection by diosgenin and L-deprenyl.
Neurobiology of disease 2006;23(1):109-19.
2006: Arumugam Thiruma V; Chan Sic L; Jo Dong-Gyu; Yilmaz Gokhan; Tang Sung-Chun; Cheng Aiwu; Gleichmann Marc; Okun Eitan; Dixit Vishwa D; Chigurupati Srinivasulu; Mughal Mohamed R; Ouyang Xin; Miele Lucio; Magnus Tim; Poosala Suresh; Granger D Neil; Mattson Mark P
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke.
Nature medicine 2006;12(6):621-3.
2006: Lee Jaewon; Kim So Jung; Son Tae Gen; Chan Sic L; Mattson Mark P
Interferon-gamma is up-regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity.
Journal of neuroscience research 2006;83(8):1552-7.
2006: Hyun Dong-Hoon; Hernandez Joe O; Mattson Mark P; de Cabo Rafael
The plasma membrane redox system in aging.
Ageing research reviews 2006;5(2):209-20.
2006: Arumugam Thiruma V; Gleichmann Marc; Tang Sung-Chun; Mattson Mark P
Hormesis/preconditioning mechanisms, the nervous system and aging.
Ageing research reviews 2006;5(2):165-78.
2006: Hunt Nicole D; Hyun Dong-Hoon; Allard Joanne S; Minor Robin K; Mattson Mark P; Ingram Donald K; de Cabo Rafael
Bioenergetics of aging and calorie restriction.
Ageing research reviews 2006;5(2):125-43.
2006: Lu Chengbiao; Wang Yue; Furukawa Katsutoshi; Fu Weiming; Ouyang Xin; Mattson Mark P
Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses.
Journal of neurochemistry 2006;97(4):1104-10.
2006: Luo Yongquan; Cai Jingli; Xue Haipeng; Mattson Mark P; Rao Mahendra S
SDF1alpha/CXCR4 signaling stimulates beta-catenin transcriptional activity in rat neural progenitors.
Neuroscience letters 2006;398(3):291-5.
2006: Mattson M P; Meffert M K
Roles for NF-kappaB in nerve cell survival, plasticity, and disease.
Cell death and differentiation 2006;13(5):852-60.
2006: Cai Jingli; Shin Soojung; Wright Lynda; Liu Ying; Zhou Daixing; Xue Haipeng; Khrebtukova Irina; Mattson Mark P; Svendsen Clive N; Rao Mahendra S
Massively parallel signature sequencing profiling of fetal human neural precursor cells.
Stem cells and development 2006;15(2):232-44.
2006: Maudsley Stuart; Mattson Mark P
Protein twists and turns in Alzheimer disease.
Nature medicine 2006;12(4):392-3.
2006: Mager Donald E; Wan Ruiqian; Brown Martin; Cheng Aiwu; Wareski Przemyslaw; Abernethy Darrell R; Mattson Mark P
Caloric restriction and intermittent fasting alter spectral measures of heart rate and blood pressure variability in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(6):631-7.
2006: Mattson Mark P; Magnus Tim
Ageing and neuronal vulnerability.
Nature reviews. Neuroscience 2006;7(4):278-94.
2006: Zhao Yunfeng; Wang Li-ming; Chaiswing Luksana; Yen Hsiu-chuan; Oberley Terry D; Lien Yu-chin; Lin Shu-mei; Mattson Mark P; St Clair Daret
Tamoxifen protects against acute tumor necrosis factor alpha-induced cardiac injury via improving mitochondrial functions.
Free radical biology & medicine 2006;40(7):1234-41.
2006: Zhang Peisu; Furukawa Katsutoshi; Opresko Patricia L; Xu Xiangru; Bohr Vilhelm A; Mattson Mark P
TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.
Journal of neurochemistry 2006;97(2):567-81.
2006: Spencer Richard G; Fishbein Kenneth W; Cheng Aiwu; Mattson Mark P
Compatibility of Gd-DTPA perfusion and histologic studies of the brain.
Magnetic resonance imaging 2006;24(1):27-31.
2006: Lee Garrick D; Longo Dan L; Wang Yue; Rifkind Joseph M; Abdul-Raman Lilanie; Mamczarz Jacek A; Duffy Kara B; Spangler Edward L; Taub Dennis D; Mattson Mark P; Ingram Donald K
Transient improvement in cognitive function and synaptic plasticity in rats following cancer chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):198-205.
2006: Liu Dong; Chan Sic L; de Souza-Pinto Nadja C; Slevin John R; Wersto Robert P; Zhan Ming; Mustafa Khadija; de Cabo Rafael; Mattson Mark P
Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress.
Neuromolecular medicine 2006;8(3):389-414.
2006: Wang Yue; Cheng Aiwu; Mattson Mark P
The PTEN phosphatase is essential for long-term depression of hippocampal synapses.
Neuromolecular medicine 2006;8(3):329-36.
2006: Liu Ying; Shin Soojung; Zeng Xianmin; Zhan Ming; Gonzalez Rodolfo; Mueller Franz-Josef; Schwartz Catherine M; Xue Haipeng; Li Huai; Baker Shawn C; Chudin Eugene; Barker David L; McDaniel Timothy K; Oeser Steffen; Loring Jeanne F; Mattson Mark P; Rao Mahendra S
Genome wide profiling of human embryonic stem cells (hESCs), their derivatives and embryonal carcinoma cells to develop base profiles of U.S. Federal government approved hESC lines.
BMC developmental biology 2006;6():20.
2006: Li Huai; Liu Ying; Shin Soojung; Sun Yu; Loring Jeanne F; Mattson Mark P; Rao Mahendra S; Zhan Ming
Transcriptome coexpression map of human embryonic stem cells.
BMC genomics 2006;7():103.
2005: Mattson Mark P; Cutler Roy G; Jo Dong-Gyu
Alzheimer peptides perturb lipid-regulating enzymes.
Nature cell biology 2005;7(11):1045-7.
2005: Ahmet Ismayil; Wan Ruiqian; Mattson Mark P; Lakatta Edward G; Talan Mark
Cardioprotection by intermittent fasting in rats.
Circulation 2005;112(20):3115-21.
2005: McCampbell Alexander; Truong David; Broom Daniel C; Allchorne Andrew; Gable Ken; Cutler Roy G; Mattson Mark P; Woolf Clifford J; Frosch Matthew P; Harmon Jeffrey M; Dunn Teresa M; Brown Robert H
Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.
Human molecular genetics 2005;14(22):3507-21.
2005: Li W; Galey D; Mattson M P; Nath A
Molecular and cellular mechanisms of neuronal cell death in HIV dementia.
Neurotoxicity research 2005;8(1-2):119-34.
2005: Mattson Mark P; Gleichmann Marc
The neuronal death protein par-4 mediates dopaminergic synaptic plasticity.
Molecular interventions 2005;5(5):278-81.
2005: Guiotto Andrea; Calderan Andrea; Ruzza Paolo; Osler Alessio; Rubini Chiara; Jo Dong-Gyu; Mattson Mark P; Borin Gianfranco
Synthesis and evaluation of neuroprotective alpha,beta-unsaturated aldehyde scavenger histidyl-containing analogues of carnosine.
Journal of medicinal chemistry 2005;48(19):6156-61.
2005: Mattson M P; Haughey N J; Nath A
Cell death in HIV dementia.
Cell death and differentiation 2005;12 Suppl 1():893-904.
2005: Kruman Inna I; Mouton Peter R; Emokpae Roland; Cutler Roy G; Mattson Mark P
Folate deficiency inhibits proliferation of adult hippocampal progenitors.
Neuroreport 2005;16(10):1055-9.
2005: Mattson Mark P
NF-kappaB in the survival and plasticity of neurons.
Neurochemical research 2005;30(6-7):883-93.
2005: Mattson Mark P
The need for controlled studies of the effects of meal frequency on health.
Lancet 2005;365(9475):1978-80.
2005: Hasegawa Tohru; Ukai Wataru; Jo Dong-Gyu; Xu Xiangru; Mattson Mark P; Nakagawa Masaya; Araki Wataru; Saito Toshikazu; Yamada Tatsuo
Homocysteic acid induces intraneuronal accumulation of neurotoxic Abeta42: implications for the pathogenesis of Alzheimer's disease.
Journal of neuroscience research 2005;80(6):869-76.
2005: Culmsee Carsten; Mattson Mark P
p53 in neuronal apoptosis.
Biochemical and biophysical research communications 2005;331(3):761-77.
2005: Camandola Simonetta; Cutler Roy G; Gary Devin S; Milhavet Ollivier; Mattson Mark P
Suppression of calcium release from inositol 1,4,5-trisphosphate-sensitive stores mediates the anti-apoptotic function of nuclear factor-kappaB.
The Journal of biological chemistry 2005;280(23):22287-96.
2005: Liu Dong; Wu Liejun; Breyer Richard; Mattson Mark P; Andreasson Katrin
Neuroprotection by the PGE2 EP2 receptor in permanent focal cerebral ischemia.
Annals of neurology 2005;57(5):758-61.
2005: Mattson Mark P; Wan Ruiqian
Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems.
The Journal of nutritional biochemistry 2005;16(3):129-37.
2005: Petkova Aneta T; Leapman Richard D; Guo Zhihong; Yau Wai-Ming; Mattson Mark P; Tycko Robert
Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils.
Science (New York, N.Y.) 2005;307(5707):262-5.
2005: Sun Xiaoyan; Beglopoulos Vassilios; Mattson Mark P; Shen Jie
Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
Neuro-degenerative diseases 2005;2(1):6-15.
2005: Arumugam Thiruma V; Granger D Neil; Mattson Mark P
Stroke and T-cells.
Neuromolecular medicine 2005;7(3):229-42.
2005: Martin Bronwen; Lopez de Maturana Rakel; Brenneman Randall; Walent Tom; Mattson Mark P; Maudsley Stuart
Class II G protein-coupled receptors and their ligands in neuronal function and protection.
Neuromolecular medicine 2005;7(1-2):3-36.
2005: Mattson Mark P
Energy intake, meal frequency, and health: a neurobiological perspective.
Annual review of nutrition 2005;25():237-60.
2005: Mattson Mark P
Human fetal brain cell culture.
Methods in molecular medicine 2005;107():163-71.
2004: Greig Nigel H; Mattson Mark P; Perry Tracyann; Chan Sic L; Giordano Tony; Sambamurti Kumar; Rogers Jack T; Ovadia Haim; Lahiri Debomoy K
New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists.
Annals of the New York Academy of Sciences 2004;1035():290-315.
2004: Maswood Navin; Young Jennifer; Tilmont Edward; Zhang Zhiming; Gash Don M; Gerhardt Greg A; Grondin Richard; Roth George S; Mattison Julie; Lane Mark A; Carson Richard E; Cohen Robert M; Mouton Peter R; Quigley Christopher; Mattson Mark P; Ingram Donald K
Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):18171-6.
2004: Miura Takumi; Mattson Mark P; Rao Mahendra S
Cellular lifespan and senescence signaling in embryonic stem cells.
Aging cell 2004;3(6):333-43.
2004: Levenson Cathy W; Cutler Roy G; Ladenheim Bruce; Cadet Jean L; Hare Joan; Mattson Mark P
Role of dietary iron restriction in a mouse model of Parkinson's disease.
Experimental neurology 2004;190(2):506-14.
2004: Mattson Mark P; Maudsley Stuart; Martin Bronwen
A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin.
Ageing research reviews 2004;3(4):445-64.
2004: Mattson Mark P; Taub Dennis D
Ancient viral protein enrages astrocytes in multiple sclerosis.
Nature neuroscience 2004;7(10):1021-3.
2004: Mattson Mark P; Maudsley Stuart; Martin Bronwen
BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders.
Trends in neurosciences 2004;27(10):589-94.
2004: Verkhratsky Alex; Mattson Mark P; Toescu Emil C
Aging in the mind.
Trends in neurosciences 2004;27(10):577-8.
2004: Kruman Inna I; Schwartz Elena; Kruman Yuri; Cutler Roy G; Zhu Xiaoxiang; Greig Nigel H; Mattson Mark P
Suppression of uracil-DNA glycosylase induces neuronal apoptosis.
The Journal of biological chemistry 2004;279(42):43952-60.
2004: Stein Thor D; Anders Nicholas J; DeCarli Charles; Chan Sic L; Mattson Mark P; Johnson Jeffrey A
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(35):7707-17.
2004: Wan Ruiqian; Camandola Simonetta; Mattson Mark P
Dietary supplementation with 2-deoxy-D-glucose improves cardiovascular and neuroendocrine stress adaptation in rats.
American journal of physiology. Heart and circulatory physiology 2004;287(3):H1186-93.
2004: Cutler R G; Haughey N J; Tammara A; McArthur J C; Nath A; Reid R; Vargas D L; Pardo C A; Mattson M P
Dysregulation of sphingolipid and sterol metabolism by ApoE4 in HIV dementia.
Neurology 2004;63(4):626-30.
2004: Mattson Mark P
Pathways towards and away from Alzheimer's disease.
Nature 2004;430(7000):631-9.
2004: Chalimoniuk Malgorzata; King-Pospisil Kelley; Pedersen Ward A; Malecki Andrzej; Wylegala Edward; Mattson Mark P; Hennig Bernhard; Toborek Michal
Arachidonic acid increases choline acetyltransferase activity in spinal cord neurons through a protein kinase C-mediated mechanism.
Journal of neurochemistry 2004;90(3):629-36.
2004: Getchell Thomas V; Peng Xuejun; Green C Paul; Stromberg Arnold J; Chen Kuey-Chu; Mattson Mark P; Getchell Marilyn L
In silico analysis of gene expression profiles in the olfactory mucosae of aging senescence-accelerated mice.
Journal of neuroscience research 2004;77(3):430-52.
2004: Cheng Aiwu; Tang Hongyan; Cai Jingli; Zhu Min; Zhang Xiaoyu; Rao Mahendra; Mattson Mark P
Gap junctional communication is required to maintain mouse cortical neural progenitor cells in a proliferative state.
Developmental biology 2004;272(1):203-16.
2004: Chan Sic L; Fu Weiming; Zhang Peisu; Cheng Aiwu; Lee Jaewon; Kokame Koichi; Mattson Mark P
Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress.
The Journal of biological chemistry 2004;279(27):28733-43.
2004: Wang Yue; Chan Sic L; Miele Lucio; Yao Pamela J; Mackes Jennifer; Ingram Donald K; Mattson Mark P; Furukawa Katsutoshi
Involvement of Notch signaling in hippocampal synaptic plasticity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(25):9458-62.
2004: Duan Wenzhen; Guo Zhihong; Jiang Haiyang; Ladenheim Bruce; Xu Xiangru; Cadet Jean Lud; Mattson Mark P
Paroxetine retards disease onset and progression in Huntingtin mutant mice.
Annals of neurology 2004;55(4):590-4.
2004: Thompson Charles; Gary Devin; Mattson Mark; Mackenzie Alex; Robertson George S
Kainic acid-induced naip expression in the hippocampus is blocked in mice lacking TNF receptors.
Brain research. Molecular brain research 2004;123(1-2):126-31.
2004: Mattson Mark P
Metal-catalyzed disruption of membrane protein and lipid signaling in the pathogenesis of neurodegenerative disorders.
Annals of the New York Academy of Sciences 2004;1012():37-50.
2004: Wang Yue; Haughey Norman J; Mattson Mark P; Furukawa Katsutoshi
Dual effects of ATP on rat hippocampal synaptic plasticity.
Neuroreport 2004;15(4):633-6.
2004: Kruman Inna I; Wersto Robert P; Cardozo-Pelaez Fernando; Smilenov Lubomir; Chan Sic L; Chrest Francis J; Emokpae Roland; Gorospe Myriam; Mattson Mark P
Cell cycle activation linked to neuronal cell death initiated by DNA damage.
Neuron 2004;41(4):549-61.
2004: Cutler Roy G; Kelly Jeremiah; Storie Kristin; Pedersen Ward A; Tammara Anita; Hatanpaa Kimmo; Troncoso Juan C; Mattson Mark P
Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):2070-5.
2004: Haughey Norman J; Cutler Roy G; Tamara Anita; McArthur Justin C; Vargas Diana L; Pardo Carlos A; Turchan Jadwiga; Nath Avindra; Mattson Mark P
Perturbation of sphingolipid metabolism and ceramide production in HIV-dementia.
Annals of neurology 2004;55(2):257-67.
2004: Mattson Mark P; Duan Wenzhen; Wan Ruqian; Guo Zhihong
Prophylactic activation of neuroprotective stress response pathways by dietary and behavioral manipulations.
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 2004;1(1):111-6.
2004: Mattson Mark P
Infectious agents and age-related neurodegenerative disorders.
Ageing research reviews 2004;3(1):105-20.
2004: Cai Jingli; Cheng Aiwu; Luo Yongquan; Lu Chengbiao; Mattson Mark P; Rao Mahendra S; Furukawa Katsutoshi
Membrane properties of rat embryonic multipotent neural stem cells.
Journal of neurochemistry 2004;88(1):212-26.
2004: Guo Zhihong; Iyun Titilola; Fu Weiming; Zhang Peisu; Mattson Mark P
Bone marrow transplantation reveals roles for brain macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death.
Neuromolecular medicine 2004;5(3):219-34.
2003: Milhavet Ollivier; Gary Devin S; Mattson Mark P
RNA interference in biology and medicine.
Pharmacological reviews 2003;55(4):629-48.
2003: Mattson Mark P; Chan Sic L
Calcium orchestrates apoptosis.
Nature cell biology 2003;5(12):1041-3.
2003: Gilman Charles P; Perry TracyAnn; Furukawa Katsotoshi; Grieg Nigel H; Egan Josephine M; Mattson Mark P
Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons.
Journal of neurochemistry 2003;87(5):1137-44.
2003: Mattson Mark P
Adventures in neural plasticity, aging, and neurodegenerative disorders aboard the CWC beagle.
Neurochemical research 2003;28(11):1631-7.
2003: Furukawa Katsutoshi; Wang Yue; Yao Pamela J; Fu Weiming; Mattson Mark P; Itoyama Yasuto; Onodera Hiroshi; D'Souza Ian; Poorkaj Parvone H; Bird Thomas D; Schellenberg Gerard D
Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation.
Journal of neurochemistry 2003;87(2):427-36.
2003: Mattson Mark P; Chan Sic L
Neuronal and glial calcium signaling in Alzheimer's disease.
Cell calcium 2003;34(4-5):385-97.
2003: Mattson Mark P; Haberman Frank
Folate and homocysteine metabolism: therapeutic targets in cardiovascular and neurodegenerative disorders.
Current medicinal chemistry 2003;10(19):1923-9.
2003: Mattson Mark P; Chan Sic L
Good and bad amyloid antibodies.
Science (New York, N.Y.) 2003;301(5641):1847-9.
2003: Culmsee Carsten; Siewe Jan; Junker Vera; Retiounskaia Marina; Schwarz Stephanie; Camandola Simonetta; El-Metainy Shahira; Behnke Hagen; Mattson Mark P; Krieglstein Josef
Reciprocal inhibition of p53 and nuclear factor-kappaB transcriptional activities determines cell survival or death in neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(24):8586-95.
2003: Mattson Mark P
Gene-diet interactions in brain aging and neurodegenerative disorders.
Annals of internal medicine 2003;139(5 Pt 2):441-4.
2003: Mattson Mark P; Perry TracyAnn; Greig Nigel H
Learning from the gut.
Nature medicine 2003;9(9):1113-5.
2003: Liu Dong; Slevin John R; Lu Chengbiao; Chan Sic L; Hansson Magnus; Elmér Eskil; Mattson Mark P
Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.
Journal of neurochemistry 2003;86(4):966-79.
2003: Oddo Salvatore; Caccamo Antonella; Shepherd Jason D; Murphy M Paul; Golde Todd E; Kayed Rakez; Metherate Raju; Mattson Mark P; Akbari Yama; LaFerla Frank M
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
Neuron 2003;39(3):409-21.
2003: Mattson Mark P
Methylation and acetylation in nervous system development and neurodegenerative disorders.
Ageing research reviews 2003;2(3):329-42.
2003: Pigino Gustavo; Morfini Gerardo; Pelsman Alejandra; Mattson Mark P; Brady Scott T; Busciglio Jorge
Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(11):4499-508.
2003: Cheng Aiwu; Wang Shuqin; Cai Jingli; Rao Mahendra S; Mattson Mark P
Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain.
Developmental biology 2003;258(2):319-33.
2003: Galey D; Becker K; Haughey N; Kalehua A; Taub D; Woodward J; Mattson M P; Nath A
Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes.
Journal of neurovirology 2003;9(3):358-71.
2003: Wan Ruiqian; Camandola Simonetta; Mattson Mark P
Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats.
The Journal of nutrition 2003;133(6):1921-9.
2003: Perry TracyAnn; Lahiri Debomoy K; Sambamurti Kumar; Chen Demao; Mattson Mark P; Egan Josephine M; Greig Nigel H
Glucagon-like peptide-1 decreases endogenous amyloid-beta peptide (Abeta) levels and protects hippocampal neurons from death induced by Abeta and iron.
Journal of neuroscience research 2003;72(5):603-12.
2003: Duan Wenzhen; Guo Zhihong; Jiang Haiyang; Ware Melvin; Mattson Mark P
Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain-derived neurotrophic factor.
Endocrinology 2003;144(6):2446-53.
2003: Wan Ruiqian; Camandola Simonetta; Mattson Mark P
Intermittent fasting and dietary supplementation with 2-deoxy-D-glucose improve functional and metabolic cardiovascular risk factors in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1133-4.
2003: Mattson Mark P; Kroemer Guido
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection.
Trends in molecular medicine 2003;9(5):196-205.
2003: Mattson Mark P; Liu Dong
Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death.
Biochemical and biophysical research communications 2003;304(3):539-49.
2003: Anson R Michael; Guo Zhihong; de Cabo Rafael; Iyun Titilola; Rios Michelle; Hagepanos Adrienne; Ingram Donald K; Lane Mark A; Mattson Mark P
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6216-20.
2003: Getchell Thomas V; Peng Xuejun; Stromberg Arnold J; Chen Kuey-Chu; Paul Green C; Subhedar Nishikant K; Shah Dharmen S; Mattson Mark P; Getchell Marilyn L
Age-related trends in gene expression in the chemosensory-nasal mucosae of senescence-accelerated mice.
Ageing research reviews 2003;2(2):211-43.
2003: Zhang Peisu; Chan Sic L; Fu Weiming; Mendoza Marty; Mattson Mark P
TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):767-9.
2003: Alves da Costa Cristine; Mattson Mark P; Ancolio Karine; Checler Frederic
The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.
The Journal of biological chemistry 2003;278(14):12064-9.
2003: Limke Tobi L; Cai Jingli; Miura Takumi; Rao Mahendra S; Mattson Mark P
Distinguishing features of progenitor cells in the late embryonic and adult hippocampus.
Developmental neuroscience 2003;25(2-4):257-72.
2003: Mattson Mark P
Neurobiology: Ballads of a protein quartet.
Nature 2003;422(6930):385, 387.
2003: Mattson Mark P; Shea Thomas B
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders.
Trends in neurosciences 2003;26(3):137-46.
2003: Duan Wenzhen; Guo Zhihong; Jiang Haiyang; Ware Melvin; Li Xiao-Jiang; Mattson Mark P
Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(5):2911-6.
2003: Mattson Mark P
Will caloric restriction and folate protect against AD and PD?
Neurology 2003;60(4):690-5.
2003: Gary Devin S; Milhavet Ollivier; Camandola Simonetta; Mattson Mark P
Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons.
Journal of neurochemistry 2003;84(4):878-90.
2003: Mattson Mark P; Duan Wenzhen; Guo Zhihong
Meal size and frequency affect neuronal plasticity and vulnerability to disease: cellular and molecular mechanisms.
Journal of neurochemistry 2003;84(3):417-31.
2003: Mattson Mark P
Insulating axons via NF-kappaB.
Nature neuroscience 2003;6(2):105-6.
2003: Cheng Aiwu; Wang Shuqin; Yang Dongmei; Xiao Ruiping; Mattson Mark P
Calmodulin mediates brain-derived neurotrophic factor cell survival signaling upstream of Akt kinase in embryonic neocortical neurons.
The Journal of biological chemistry 2003;278(9):7591-9.
2003: Lee Jaewon; Auyeung Wendy W; Mattson Mark P
Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice.
Neuromolecular medicine 2003;4(3):179-96.
2003: Mattson Mark P; Sherman Michael
Perturbed signal transduction in neurodegenerative disorders involving aberrant protein aggregation.
Neuromolecular medicine 2003;4(1-2):109-32.
2003: Trojanowski John Q; Mattson Mark P
Overview of protein aggregation in single, double, and triple neurodegenerative brain amyloidoses.
Neuromolecular medicine 2003;4(1-2):1-6.
2003: Yao P J; Zhang P; Mattson M P; Furukawa K
Heterogeneity of endocytic proteins: distribution of clathrin adaptor proteins in neurons and glia.
Neuroscience 2003;121(1):25-37.
2003: Haughey Norman J; Mattson Mark P
Alzheimer's amyloid beta-peptide enhances ATP/gap junction-mediated calcium-wave propagation in astrocytes.
Neuromolecular medicine 2003;3(3):173-80.
2003: Gilman Charles P; Chan Sic L; Guo Zhihong; Zhu Xiaoxiang; Greig Nigel; Mattson Mark P
p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults.
Neuromolecular medicine 2003;3(3):159-72.
2003: Pak Kirk J; Chan Sic L; Mattson Mark P
Homocysteine and folate deficiency sensitize oligodendrocytes to the cell death-promoting effects of a presenilin-1 mutation and amyloid beta-peptide.
Neuromolecular medicine 2003;3(2):119-28.
2003: Mattson Mark P
Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders.
Neuromolecular medicine 2003;3(2):65-94.
2003: Pak Kirk; Chan Sic L; Mattson Mark P
Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice.
Neuromolecular medicine 2003;3(1):53-64.
2003: Nath Avindra; Hall Elizabeth; Tuzova Marnia; Dobbs Michael; Jons Melina; Anderson Caroline; Woodward Jerold; Guo Zhihong; Fu Weiming; Kryscio Richard; Wekstein David; Smith Charles; Markesbery William R; Mattson Mark P
Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development.
Neuromolecular medicine 2003;3(1):29-39.
2002: Fu Weiming; Lee Jaewon; Guo Zhihong; Mattson Mark P
Seizures and tissue injury induce telomerase in hippocampal microglial cells.
Experimental neurology 2002;178(2):294-300.
2002: Fu Weiming; Lu Chengbiao; Mattson Mark P
Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(24):10710-9.
2002: Mattson Mark P
Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's disease.
Journal of neurovirology 2002;8(6):539-50.
2002: Haughey Norman J; Nath Avi; Chan Sic L; Borchard A C; Rao Mahendra S; Mattson Mark P
Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.
Journal of neurochemistry 2002;83(6):1509-24.
2002: Lu Chengbiao; Fu Weiming; Zhao Daohong; Mattson Mark P
The DNA damaging agent etoposide activates a cell survival pathway involving alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptors and mitogen-activated protein kinases in hippocampal neurons.
Journal of neuroscience research 2002;70(5):671-9.
2002: Zhu Xiaoxiang; Yu Qian-Sheng; Cutler Roy G; Culmsee Carsten W; Holloway Harold W; Lahiri Debomoy K; Mattson Mark P; Greig Nigel H
Novel p53 inactivators with neuroprotective action: syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives.
Journal of medicinal chemistry 2002;45(23):5090-7.
2002: Duan Wenzhen; Zhu Xiaoxiang; Ladenheim Bruce; Yu Qian-sheng; Guo Zhihong; Oyler Jon; Cutler Roy G; Cadet Jean Lud; Greig Nigel H; Mattson Mark P
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism.
Annals of neurology 2002;52(5):597-606.
2002: Milhavet Ollivier; Martindale Jennifer L; Camandola Simonetta; Chan Sic L; Gary Devin S; Cheng Aiwu; Holbrook Nikki J; Mattson Mark P
Involvement of Gadd153 in the pathogenic action of presenilin-1 mutations.
Journal of neurochemistry 2002;83(3):673-81.
2002: Chan Sic L; Culmsee Carsten; Haughey Norman; Klapper Wolfram; Mattson Mark P
Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12.
Neurobiology of disease 2002;11(1):2-19.
2002: Haughey Norman J; Mattson Mark P
Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins Tat and gp120.
Journal of acquired immune deficiency syndromes (1999) 2002;31 Suppl 2():S55-61.
2002: Cutler Roy G; Pedersen Ward A; Camandola Simonetta; Rothstein Jeffrey D; Mattson Mark P
Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis.
Annals of neurology 2002;52(4):448-57.
2002: Mattson Mark P; Duan Wenzhen; Chan Sic L; Cheng Aiwu; Haughey Norman; Gary Devin S; Guo Zhihong; Lee Jaewon; Furukawa Katsutoshi
Neuroprotective and neurorestorative signal transduction mechanisms in brain aging: modification by genes, diet and behavior.
Neurobiology of aging 2002;23(5):695-705.
2002: Lee Jaewon; Duan Wenzhen; Mattson Mark P
Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.
Journal of neurochemistry 2002;82(6):1367-75.
2002: Perry TracyAnn; Haughey Norman J; Mattson Mark P; Egan Josephine M; Greig Nigel H
Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4.
The Journal of pharmacology and experimental therapeutics 2002;302(3):881-8.
2002: Pedersen Ward A; Chan Sic L; Zhu Haiyan; Abdur-Rahman Lilanie A; Verdi Joseph M; Mattson Mark P
Numb isoforms containing a short PTB domain promote neurotrophic factor-induced differentiation and neurotrophic factor withdrawal-induced death of PC12 Cells.
Journal of neurochemistry 2002;82(4):976-86.
2002: Wang Yue; Mattson Mark P; Furukawa Katsutoshi
Endoplasmic reticulum calcium release is modulated by actin polymerization.
Journal of neurochemistry 2002;82(4):945-52.
2002: Conant Katherine; Haughey Norman; Nath Avindra; St Hillaire Coryse; Gary Devin S; Pardo Carlos A; Wahl Larry M; Bilak Masako; Milward Elizabeth; Mattson Mark P
Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9.
Journal of neurochemistry 2002;82(4):885-93.
2002: Tomac Andreas C; Agulnick Alan D; Haughey Norman; Chang Chen-Fu; Zhang Yajun; Bäckman Cristina; Morales Marisela; Mattson Mark P; Wang Yun; Westphal Heiner; Hoffer Barry J
Effects of cerebral ischemia in mice deficient in Persephin.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9521-6.
2002: Gary Devin S; Getchell Thomas V; Getchell Marilyn L; Mattson Mark P
Olfactory bulbectomy protects hippocampal pyramidal neurons against excitotoxic death.
Experimental neurology 2002;176(1):266-8.
2002: Mattson Mark P; Chan Sic L; Duan Wenzhen
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior.
Physiological reviews 2002;82(3):637-72.
2002: Lu Chengbiao; Chan Sic L; Fu Weiming; Mattson Mark P
The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation.
The Journal of biological chemistry 2002;277(27):24368-75.
2002: Mattson Mark P; Mattson Elliot P
Amyloid peptide enhances nail rusting: novel insight into mechanisms of aging and Alzheimer's disease.
Ageing research reviews 2002;1(3):327-30.
2002: Cheng Guanjun; Yu ZaiFang; Zhou Daohong; Mattson Mark P
Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein.
Experimental neurology 2002;175(2):407-14.
2002: Kittur Smita; Wilasrusmee Skuntala; Pedersen Ward A; Mattson Mark P; Straube-West Karen; Wilasrusmee Chumpon; Lubelt Burk; Kittur Dilip S
Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture.
Journal of molecular neuroscience : MN 2002;18(3):265-9.
2002: Van Ess Peter J; Poloyac Samuel; Mattson Mark P; Blouin Robert A
Blunted induction of hepatic CYP4A in TNF (p55-/-/p75-/-) double receptor knockout mice following clofibrate treatment.
Pharmaceutical research 2002;19(5):708-12.
2002: LaFontaine Michael A; Mattson Mark P; Butterfield D Allan
Oxidative stress in synaptosomal proteins from mutant presenilin-1 knock-in mice: implications for familial Alzheimer's disease.
Neurochemical research 2002;27(5):417-21.
2002: Lee Jaewon; Chan Sic L; Lu Chengbiao; Lane Mark A; Mattson Mark P
Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity.
Experimental neurology 2002;175(1):161-7.
2002: Mattson Mark P
Brain evolution and lifespan regulation: conservation of signal transduction pathways that regulate energy metabolism.
Mechanisms of ageing and development 2002;123(8):947-53.
2002: Mattson Mark P; Duan Wenzhen; Maswood Navin
How does the brain control lifespan?
Ageing research reviews 2002;1(2):155-65.
2002: Lilliehook C; Chan S; Choi E K; Zaidi N F; Wasco W; Mattson M P; Buxbaum J D
Calsenilin enhances apoptosis by altering endoplasmic reticulum calcium signaling.
Molecular and cellular neurosciences 2002;19(4):552-9.
2002: Liu Dong; Lu Chengbiao; Wan Ruiqian; Auyeung Wendy W; Mattson Mark P
Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2002;22(4):431-43.
2002: Alves da Costa Cristine; Paitel Erwan; Mattson Mark P; Amson Robert; Telerman Adam; Ancolio Karine; Checler Frédéric;
Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):4043-8.
2002: Kruman Inna I; Kumaravel T S; Lohani Althaf; Pedersen Ward A; Cutler Roy G; Kruman Yuri; Haughey Norman; Lee Jaewon; Evans Michele; Mattson Mark P
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(5):1752-62.
2002: Van Ess Peter J; Mattson Mark P; Blouin Robert A
Enhanced induction of cytochrome P450 enzymes and CAR binding in TNF (p55(-/-)/p75(-/-)) double receptor knockout mice following phenobarbital treatment.
The Journal of pharmacology and experimental therapeutics 2002;300(3):824-30.
2002: Mattson Mark P
Neurogenetics: white matter matters.
Trends in neurosciences 2002;25(3):135-6.
2002: Mattson Mark P; Kruman Inna I; Duan Wenzhen
Folic acid and homocysteine in age-related disease.
Ageing research reviews 2002;1(1):95-111.
2002: Lee Jaewon; Seroogy Kim B; Mattson Mark P
Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice.
Journal of neurochemistry 2002;80(3):539-47.
2002: Van Ess P J; Pedersen W A; Culmsee C; Mattson M P; Blouin R A
Elevated hepatic and depressed renal cytochrome P450 activity in the Tg2576 transgenic mouse model of Alzheimer's disease.
Journal of neurochemistry 2002;80(4):571-8.
2002: Luo Yongquan; Long Jeffery M; Lu Chengbiao; Chan Sic L; Spangler Edward L; Mascarucci Paolo; Raz Avraham; Longo Dan L; Mattson Mark P; Ingram Donald K; Weng Nan-Ping
A link between maze learning and hippocampal expression of neuroleukin and its receptor gp78.
Journal of neurochemistry 2002;80(2):354-61.
2002: Mattson Mark P
Accomplices to neuronal death.
Nature 2002;415(6870):377-9.
2002: Duan Wenzhen; Ladenheim Bruce; Cutler Roy G; Kruman Inna I; Cadet Jean Lud; Mattson Mark P
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease.
Journal of neurochemistry 2002;80(1):101-10.
2002: Pedersen Ward A; Wan Ruiqian; Zhang Peisu; Mattson Mark P
Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(2):404-12.
2002: Gary Devin S; Mattson Mark P
PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis.
Neuromolecular medicine 2002;2(3):261-9.
2002: Mattson Mark P
Contributions of mitochondrial alterations, resulting from bad genes and a hostile environment, to the pathogenesis of Alzheimer's disease.
International review of neurobiology 2002;53():387-409.
2002: Culmsee C; Gerling N; Lehmann M; Nikolova-Karakashian M; Prehn J H M; Mattson M P; Krieglstein J
Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.
Neuroscience 2002;115(4):1089-108.
2002: Mattson Mark P; Liu Dong
Energetics and oxidative stress in synaptic plasticity and neurodegenerative disorders.
Neuromolecular medicine 2002;2(2):215-31.
2002: Gilman Charles P; Mattson Mark P
Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility?
Neuromolecular medicine 2002;2(2):197-214.
2002: Chan Sic L; Furukawa Katsutoshi; Mattson Mark P
Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease.
Neuromolecular medicine 2002;2(2):167-96.
2002: Lee Jaewon; Chan Sic L; Mattson Mark P
Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain.
Neuromolecular medicine 2002;2(1):29-45.
2002: Mattson Mark P
Involvement of superoxide in pathogenic action of mutations that cause Alzheimer's disease.
Methods in enzymology 2002;352():455-74.
2002: Haughey Norman J; Liu Dong; Nath Avi; Borchard Amy C; Mattson Mark P
Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease.
Neuromolecular medicine 2002;1(2):125-35.
2002: Lu Chengbiao; Fu Weiming; Salvesen Guy S; Mattson Mark P
Direct cleavage of AMPA receptor subunit GluR1 and suppression of AMPA currents by caspase-3: implications for synaptic plasticity and excitotoxic neuronal death.
Neuromolecular medicine 2002;1(1):69-79.
2002: Chan Sic L; Pedersen Ward A; Zhu Hiayan; Mattson Mark P
Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease.
Neuromolecular medicine 2002;1(1):55-67.
2002: Mattson Mark P; Zhang Peisu; Fu Weiming
Assessing the involvement of telomerase in stem cell biology.
Methods in molecular biology (Clifton, N.J.) 2002;198():125-36.
2001: Mattson M P
Stem cells as therapeutics for neurodegenerative disorders?
Expert review of neurotherapeutics 2001;1(2):267-73.
2001: Prolla T A; Mattson M P
Molecular mechanisms of brain aging and neurodegenerative disorders: lessons from dietary restriction.
Trends in neurosciences 2001;24(11 Suppl):S21-31.
2001: Lu C; Fu W; Mattson M P
Telomerase protects developing neurons against DNA damage-induced cell death.
Brain research. Developmental brain research 2001;131(1-2):167-71.
2001: Cheng A; Chan S L; Milhavet O; Wang S; Mattson M P
p38 MAP kinase mediates nitric oxide-induced apoptosis of neural progenitor cells.
The Journal of biological chemistry 2001;276(46):43320-7.
2001: Mattson M P; Chan S L
Dysregulation of cellular calcium homeostasis in Alzheimer's disease: bad genes and bad habits.
Journal of molecular neuroscience : MN 2001;17(2):205-24.
2001: Warren G W; van Ess P J; Watson A M; Mattson M P; Blouin R A
Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(10):821-6.
2001: Guo Z; Lee J; Lane M; Mattson M
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2.
Journal of neurochemistry 2001;79(2):361-70.
2001: Culmsee C; Monnig J; Kemp B E; Mattson M P
AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.
Journal of molecular neuroscience : MN 2001;17(1):45-58.
2001: Mattson M P; Chan S L; Camandola S
Presenilin mutations and calcium signaling defects in the nervous and immune systems.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(8):733-44.
2001: Lu C; Chan S L; Haughey N; Lee W T; Mattson M P
Selective and biphasic effect of the membrane lipid peroxidation product 4-hydroxy-2,3-nonenal on N-methyl-D-aspartate channels.
Journal of neurochemistry 2001;78(3):577-89.
2001: Haughey N J; Nath A; Mattson M P; Slevin J T; Geiger J D
HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity.
Journal of neurochemistry 2001;78(3):457-67.
2001: Mattson M P
A multi-talented secreted protein.
Trends in neurosciences 2001;24(8):441-2.
2001: Zhou D; Yu T; Chen G; Brown S A; Yu Z; Mattson M P; Thompson J S
Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo.
International journal of radiation biology 2001;77(7):763-72.
2001: Lu C; Mattson M P
Dimethyl sulfoxide suppresses NMDA- and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons.
Experimental neurology 2001;170(1):180-5.
2001: Pedersen W A; Wan R; Mattson M P
Impact of aging on stress-responsive neuroendocrine systems.
Mechanisms of ageing and development 2001;122(9):963-83.
2001: Cutler R G; Mattson M P
Sphingomyelin and ceramide as regulators of development and lifespan.
Mechanisms of ageing and development 2001;122(9):895-908.
2001: Pedersen W A; McCullers D; Culmsee C; Haughey N J; Herman J P; Mattson M P
Corticotropin-releasing hormone protects neurons against insults relevant to the pathogenesis of Alzheimer's disease.
Neurobiology of disease 2001;8(3):492-503.
2001: Mattson M P
Lose weight STAT: CNTF tops leptin.
Trends in neurosciences 2001;24(6):313-4.
2001: Glazner G W; Camandola S; Geiger J D; Mattson M P
Endoplasmic reticulum D-myo-inositol 1,4,5-trisphosphate-sensitive stores regulate nuclear factor-kappaB binding activity in a calcium-independent manner.
The Journal of biological chemistry 2001;276(25):22461-7.
2001: Mattson M P; Duan W; Lee J; Guo Z
Suppression of brain aging and neurodegenerative disorders by dietary restriction and environmental enrichment: molecular mechanisms.
Mechanisms of ageing and development 2001;122(7):757-78.
2001: Rao M S; Mattson M P
Stem cells and aging: expanding the possibilities.
Mechanisms of ageing and development 2001;122(7):713-34.
2001: Mattson M P; Fu W; Zhang P
Emerging roles for telomerase in regulating cell differentiation and survival: a neuroscientist's perspective.
Mechanisms of ageing and development 2001;122(7):659-71.
2001: Klapper W; Shin T; Mattson M P
Differential regulation of telomerase activity and TERT expression during brain development in mice.
Journal of neuroscience research 2001;64(3):252-60.
2001: Mattson M P
Neuronal death and GSK-3beta: a tau fetish?
Trends in neurosciences 2001;24(5):255-6.
2001: Culmsee C; Zhu Y; Krieglstein J; Mattson M P
Evidence for the involvement of Par-4 in ischemic neuron cell death.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2001;21(4):334-43.
2001: Lu C; Fu W; Mattson M P
Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative disorders.
Neurobiology of disease 2001;8(2):194-206.
2001: Culmsee C; Zhu X; Yu Q S; Chan S L; Camandola S; Guo Z; Greig N H; Mattson M P
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
Journal of neurochemistry 2001;77(1):220-8.
2001: Culmsee C; Bondada S; Mattson M P
Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.
Brain research. Molecular brain research 2001;87(2):257-62.
2001: Gary D S; Mattson M P
Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis.
Journal of neurochemistry 2001;76(5):1485-96.
2001: Garrido R; Mattson M P; Hennig B; Toborek M
Nicotine protects against arachidonic-acid-induced caspase activation, cytochrome c release and apoptosis of cultured spinal cord neurons.
Journal of neurochemistry 2001;76(5):1395-403.
2001: Duan W; Lee J; Guo Z; Mattson M P
Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury.
Journal of molecular neuroscience : MN 2001;16(1):1-12.
2001: Mattson M P; Duan W; Pedersen W A; Culmsee C
Neurodegenerative disorders and ischemic brain diseases.
Apoptosis : an international journal on programmed cell death 2001;6(1-2):69-81.
2001: Mattson M P
Does DNA damage sculpt the developing brain?
Trends in neurosciences 2001;24(2):77.
2001: Mattson M P; Camandola S
NF-kappaB in neuronal plasticity and neurodegenerative disorders.
The Journal of clinical investigation 2001;107(3):247-54.
2001: Duan W; Guo Z; Mattson M P
Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice.
Journal of neurochemistry 2001;76(2):619-26.
2001: Mattson M P; Klapper W
Emerging roles for telomerase in neuronal development and apoptosis.
Journal of neuroscience research 2001;63(1):1-9.
2001: Mattson M P
New blood cells help an overburdened brain.
Trends in neurosciences 2001;24(1):5.
2001: Mattson M P; Gary D S; Chan S L; Duan W
Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.
Biochemical Society symposium 2001;(67):151-62.
2001: Turchan J; Anderson C; Hauser K F; Sun Q; Zhang J; Liu Y; Wise P M; Kruman I; Maragos W; Mattson M P; Booze R; Nath A
Estrogen protects against the synergistic toxicity by HIV proteins, methamphetamine and cocaine.
BMC neuroscience 2001;2():3.
2000: Camandola S; Poli G; Mattson M P
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
Brain research. Molecular brain research 2000;85(1-2):53-60.
2000: Mattson M P
Neuroprotective signaling and the aging brain: take away my food and let me run.
Brain research 2000;886(1-2):47-53.
2000: Lee J; Herman J P; Mattson M P
Dietary restriction selectively decreases glucocorticoid receptor expression in the hippocampus and cerebral cortex of rats.
Experimental neurology 2000;166(2):435-41.
2000: Mattson M P
Apoptosis in neurodegenerative disorders.
Nature reviews. Molecular cell biology 2000;1(2):120-9.
2000: Sullivan P G; Geiger J D; Mattson M P; Scheff S W
Dietary supplement creatine protects against traumatic brain injury.
Annals of neurology 2000;48(5):723-9.
2000: Guo Z H; Mattson M P
In vivo 2-deoxyglucose administration preserves glucose and glutamate transport and mitochondrial function in cortical synaptic terminals after exposure to amyloid beta-peptide and iron: evidence for a stress response.
Experimental neurology 2000;166(1):173-9.
2000: Lee J; Duan W; Long J M; Ingram D K; Mattson M P
Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.
Journal of molecular neuroscience : MN 2000;15(2):99-108.
2000: Yu Z F; Nikolova-Karakashian M; Zhou D; Cheng G; Schuchman E H; Mattson M P
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis.
Journal of molecular neuroscience : MN 2000;15(2):85-97.
2000: Mattson M P; Barger S W; Dantzer R
Silencing survival data.
Trends in neurosciences 2000;23(10):466-7.
2000: Xie J; Guo Q; Zhu H; Wooten M W; Mattson M P
Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide.
Brain research. Molecular brain research 2000;82(1-2):107-13.
2000: Bruce-Keller A J; Keeling J L; Keller J N; Huang F F; Camondola S; Mattson M P
Antiinflammatory effects of estrogen on microglial activation.
Endocrinology 2000;141(10):3646-56.
2000: Kruman I I; Culmsee C; Chan S L; Kruman Y; Guo Z; Penix L; Mattson M P
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6920-6.
2000: Duan W; Guo Z; Mattson M P
Participation of par-4 in the degeneration of striatal neurons induced by metabolic compromise with 3-nitropropionic acid.
Experimental neurology 2000;165(1):1-11.
2000: Yu Z; Zhou D; Cheng G; Mattson M P
Neuroprotective role for the p50 subunit of NF-kappaB in an experimental model of Huntington's disease.
Journal of molecular neuroscience : MN 2000;15(1):31-44.
2000: Rabchevsky A G; Fugaccia I; Turner A F; Blades D A; Mattson M P; Scheff S W
Basic fibroblast growth factor (bFGF) enhances functional recovery following severe spinal cord injury to the rat.
Experimental neurology 2000;164(2):280-91.
2000: Mattson M P
Turning off the anxiety master switch.
Trends in neurosciences 2000;23(8):333.
2000: Mattson M P
Emerging neuroprotective strategies for Alzheimer's disease: dietary restriction, telomerase activation, and stem cell therapy.
Experimental gerontology 2000;35(4):489-502.
2000: Mattson M P; Culmsee C; Yu Z F
Apoptotic and antiapoptotic mechanisms in stroke.
Cell and tissue research 2000;301(1):173-87.
2000: Mattson M P
Activin to the rescue for overexcited neurons.
Nature medicine 2000;6(7):739-41.
2000: Camandola S; Mattson M P
Pro-apoptotic action of PAR-4 involves inhibition of NF-kappaB activity and suppression of BCL-2 expression.
Journal of neuroscience research 2000;61(2):134-9.
2000: Guo Z; Ersoz A; Butterfield D A; Mattson M P
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid.
Journal of neurochemistry 2000;75(1):314-20.
2000: Zhu H; Fu W; Mattson M P
The catalytic subunit of telomerase protects neurons against amyloid beta-peptide-induced apoptosis.
Journal of neurochemistry 2000;75(1):117-24.
2000: Glazner G W; Camandola S; Mattson M P
Nuclear factor-kappaB mediates the cell survival-promoting action of activity-dependent neurotrophic factor peptide-9.
Journal of neurochemistry 2000;75(1):101-8.
2000: Mattson M P; Haddon R C; Rao A M
Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth.
Journal of molecular neuroscience : MN 2000;14(3):175-82.
2000: Malecki A; Garrido R; Mattson M P; Hennig B; Toborek M
4-Hydroxynonenal induces oxidative stress and death of cultured spinal cord neurons.
Journal of neurochemistry 2000;74(6):2278-87.
2000: Chan S L; Mayne M; Holden C P; Geiger J D; Mattson M P
Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons.
The Journal of biological chemistry 2000;275(24):18195-200.
2000: Leissring M A; Akbari Y; Fanger C M; Cahalan M D; Mattson M P; LaFerla F M
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.
The Journal of cell biology 2000;149(4):793-8.
2000: Glazner G W; Chan S L; Lu C; Mattson M P
Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3641-9.
2000: Pedersen W A; Luo H; Kruman I; Kasarskis E; Mattson M P
The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):913-24.
2000: Mattson M P; LaFerla F M; Chan S L; Leissring M A; Shepel P N; Geiger J D
Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders.
Trends in neurosciences 2000;23(5):222-9.
2000: Steiner M R; Holtsberg F W; Keller J N; Mattson M P; Steiner S M
Lysophosphatidic acid induction of neuronal apoptosis and necrosis.
Annals of the New York Academy of Sciences 2000;905():132-41.
2000: Mattson M P
Apoptotic and anti-apoptotic synaptic signaling mechanisms.
Brain pathology (Zurich, Switzerland) 2000;10(2):300-12.
2000: Albensi B C; Sullivan P G; Thompson M B; Scheff S W; Mattson M P
Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity.
Experimental neurology 2000;162(2):385-9.
2000: Pedersen W A; Chan S L; Mattson M P
A mechanism for the neuroprotective effect of apolipoprotein E: isoform-specific modification by the lipid peroxidation product 4-hydroxynonenal.
Journal of neurochemistry 2000;74(4):1426-33.
2000: Guo Z; Kindy M S; Kruman I; Mattson M P
ALS-linked Cu/Zn-SOD mutation impairs cerebral synaptic glucose and glutamate transport and exacerbates ischemic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(3):463-8.
2000: Fu W; Killen M; Culmsee C; Dhar S; Pandita T K; Mattson M P
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function.
Journal of molecular neuroscience : MN 2000;14(1-2):3-15.
2000: Toborek M; Garrido R; Malecki A; Kaiser S; Mattson M P; Hennig B; Young B
Nicotine attenuates arachidonic acid-induced overexpression of nitric oxide synthase in cultured spinal cord neurons.
Experimental neurology 2000;161(2):609-20.
2000: Glazner G W; Mattson M P
Differential effects of BDNF, ADNF9, and TNFalpha on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity.
Experimental neurology 2000;161(2):442-52.
2000: Mattson M P; Zhu H; Yu J; Kindy M S
Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(4):1358-64.
2000: Mattson M P; Culmsee C; Yu Z; Camandola S
Roles of nuclear factor kappaB in neuronal survival and plasticity.
Journal of neurochemistry 2000;74(2):443-56.
2000: Albensi B C; Mattson M P
Evidence for the involvement of TNF and NF-kappaB in hippocampal synaptic plasticity.
Synapse (New York, N.Y.) 2000;35(2):151-9.
2000: Gary D S; Sooy K; Chan S L; Christakos S; Mattson M P
Concentration- and cell type-specific effects of calbindin D28k on vulnerability of hippocampal neurons to seizure-induced injury.
Brain research. Molecular brain research 2000;75(1):89-95.
2000: Guo Z H; Mattson M P
Neurotrophic factors protect cortical synaptic terminals against amyloid and oxidative stress-induced impairment of glucose transport, glutamate transport and mitochondrial function.
Cerebral cortex (New York, N.Y. : 1991) 2000;10(1):50-7.
2000: Camandola S; Poli G; Mattson M P
The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.
Journal of neurochemistry 2000;74(1):159-68.
2000: Mattson M P
Existing data suggest that Alzheimer's disease is preventable.
Annals of the New York Academy of Sciences 2000;924():153-9.
2000: Nath A; Anderson C; Jones M; Maragos W; Booze R; Mactutus C; Bell J; Hauser K F; Mattson M
Neurotoxicity and dysfunction of dopaminergic systems associated with AIDS dementia.
Journal of psychopharmacology (Oxford, England) 2000;14(3):222-7.
1999: Tan J; Town T; Paris D; Mori T; Suo Z; Crawford F; Mattson M P; Flavell R A; Mullan M
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.
Science (New York, N.Y.) 1999;286(5448):2352-5.
1999: Glazner G W; Boland A; Dresse A E; Brenneman D E; Gozes I; Mattson M P
Activity-dependent neurotrophic factor peptide (ADNF9) protects neurons against oxidative stress-induced death.
Journal of neurochemistry 1999;73(6):2341-7.
1999: Kruman I I; Pedersen W A; Springer J E; Mattson M P
ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
Experimental neurology 1999;160(1):28-39.
1999: Herbst U; Toborek M; Kaiser S; Mattson M P; Hennig B
4-Hydroxynonenal induces dysfunction and apoptosis of cultured endothelial cells.
Journal of cellular physiology 1999;181(2):295-303.
1999: Yu Z; Zhou D; Bruce-Keller A J; Kindy M S; Mattson M P
Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(20):8856-65.
1999: Duan W; Zhang Z; Gash D M; Mattson M P
Participation of prostate apoptosis response-4 in degeneration of dopaminergic neurons in models of Parkinson's disease.
Annals of neurology 1999;46(4):587-97.
1999: Chan S L; Mattson M P
Caspase and calpain substrates: roles in synaptic plasticity and cell death.
Journal of neuroscience research 1999;58(1):167-90.
1999: Mattson M P; Duan W
"Apoptotic" biochemical cascades in synaptic compartments: roles in adaptive plasticity and neurodegenerative disorders.
Journal of neuroscience research 1999;58(1):152-66.
1999: Mattson M P; Bruce-Keller A J
Compartmentalization of signaling in neurons: evolution and deployment.
Journal of neuroscience research 1999;58(1):2-9.
1999: Zhu H; Guo Q; Mattson M P
Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation.
Brain research 1999;842(1):224-9.
1999: Rabchevsky A G; Fugaccia I; Fletcher-Turner A; Blades D A; Mattson M P; Scheff S W
Basic fibroblast growth factor (bFGF) enhances tissue sparing and functional recovery following moderate spinal cord injury.
Journal of neurotrauma 1999;16(9):817-30.
1999: Zhang D; Dhillon H S; Mattson M P; Yurek D M; Prasad R M
Immunohistochemical detection of the lipid peroxidation product 4-hydroxynonenal after experimental brain injury in the rat.
Neuroscience letters 1999;272(1):57-61.
1999: Yu Z F; Mattson M P
Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism.
Journal of neuroscience research 1999;57(6):830-9.
1999: Mattson M P
Establishment and plasticity of neuronal polarity.
Journal of neuroscience research 1999;57(5):577-89.
1999: Pedersen W A; Culmsee C; Ziegler D; Herman J P; Mattson M P
Aberrant stress response associated with severe hypoglycemia in a transgenic mouse model of Alzheimer's disease.
Journal of molecular neuroscience : MN 1999;13(1-2):159-65.
1999: Mattson M P; Duan W; Chan S L; Camandola S
Par-4: an emerging pivotal player in neuronal apoptosis and neurodegenerative disorders.
Journal of molecular neuroscience : MN 1999;13(1-2):17-30.
1999: Tolar M; Keller J N; Chan S; Mattson M P; Marques M A; Crutcher K A
Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(16):7100-10.
1999: Toborek M; Malecki A; Garrido R; Mattson M P; Hennig B; Young B
Arachidonic acid-induced oxidative injury to cultured spinal cord neurons.
Journal of neurochemistry 1999;73(2):684-92.
1999: Mattson M P; Guo Z H; Geiger J D
Secreted form of amyloid precursor protein enhances basal glucose and glutamate transport and protects against oxidative impairment of glucose and glutamate transport in synaptosomes by a cyclic GMP-mediated mechanism.
Journal of neurochemistry 1999;73(2):532-7.
1999: Chan S L; Tammariello S P; Estus S; Mattson M P
Prostate apoptosis response-4 mediates trophic factor withdrawal-induced apoptosis of hippocampal neurons: actions prior to mitochondrial dysfunction and caspase activation.
Journal of neurochemistry 1999;73(2):502-12.
1999: Sullivan P G; Bruce-Keller A J; Rabchevsky A G; Christakos S; Clair D K; Mattson M P; Scheff S W
Exacerbation of damage and altered NF-kappaB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(15):6248-56.
1999: Chan S L; Griffin W S; Mattson M P
Evidence for caspase-mediated cleavage of AMPA receptor subunits in neuronal apoptosis and Alzheimer's disease.
Journal of neuroscience research 1999;57(3):315-23.
1999: Duan W; Mattson M P
Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.
Journal of neuroscience research 1999;57(2):195-206.
1999: Lee J; Bruce-Keller A J; Kruman Y; Chan S L; Mattson M P
2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.
Journal of neuroscience research 1999;57(1):48-61.
1999: Kruman I I; Nath A; Maragos W F; Chan S L; Jones M; Rangnekar V M; Jakel R J; Mattson M P
Evidence that Par-4 participates in the pathogenesis of HIV encephalitis.
The American journal of pathology 1999;155(1):39-46.
1999: Pedersen W A; Mattson M P
No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice.
Brain research 1999;833(1):117-20.
1999: Guo Q; Fu W; Holtsberg F W; Steiner S M; Mattson M P
Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations.
Journal of neuroscience research 1999;56(5):457-70.
1999: Duan W; Rangnekar V M; Mattson M P
Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration.
Journal of neurochemistry 1999;72(6):2312-22.
1999: Keller J N; Hanni K B; Gabbita S P; Friebe V; Mattson M P; Kindy M S
Oxidized lipoproteins increase reactive oxygen species formation in microglia and astrocyte cell lines.
Brain research 1999;830(1):10-5.
1999: Keller J N; Hanni K B; Pedersen W A; Cashman N R; Mattson M P; Gabbita S P; Friebe V; Markesbery W R
Opposing actions of native and oxidized lipoprotein on motor neuron-like cells.
Experimental neurology 1999;157(1):202-10.
1999: Mattson M P; Partin J
Evidence for mitochondrial control of neuronal polarity.
Journal of neuroscience research 1999;56(1):8-20.
1999: Guo Q; Sebastian L; Sopher B L; Miller M W; Glazner G W; Ware C B; Martin G M; Mattson M P
Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):4125-30.
1999: Fu W; Begley J G; Killen M W; Mattson M P
Anti-apoptotic role of telomerase in pheochromocytoma cells.
The Journal of biological chemistry 1999;274(11):7264-71.
1999: Begley J G; Duan W; Chan S; Duff K; Mattson M P
Altered calcium homeostasis and mitochondrial dysfunction in cortical synaptic compartments of presenilin-1 mutant mice.
Journal of neurochemistry 1999;72(3):1030-9.
1999: Guo Q; Sebastian L; Sopher B L; Miller M W; Ware C B; Martin G M; Mattson M P
Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
Journal of neurochemistry 1999;72(3):1019-29.
1999: Warren G W; Poloyac S M; Gary D S; Mattson M P; Blouin R A
Hepatic cytochrome P-450 expression in tumor necrosis factor-alpha receptor (p55/p75) knockout mice after endotoxin administration.
The Journal of pharmacology and experimental therapeutics 1999;288(3):945-50.
1999: Yu Z; Luo H; Fu W; Mattson M P
The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.
Experimental neurology 1999;155(2):302-14.
1999: Kruman I I; Mattson M P
Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis.
Journal of neurochemistry 1999;72(2):529-40.
1999: Endres M; Fink K; Zhu J; Stagliano N E; Bondada V; Geddes J W; Azuma T; Mattson M P; Kwiatkowski D J; Moskowitz M A
Neuroprotective effects of gelsolin during murine stroke.
The Journal of clinical investigation 1999;103(3):347-54.
1999: Geddes J W; Tekirian T L; Mattson M P
N-terminus truncated beta-amyloid peptides and C-terminus truncated secreted forms of amyloid precursor protein: distinct roles in the pathogenesis of Alzheimer's disease.
Neurobiology of aging 1999;20(1):75-9; discussion 87.
1999: Bruce-Keller A J; Geddes J W; Knapp P E; McFall R W; Keller J N; Holtsberg F W; Parthasarathy S; Steiner S M; Mattson M P
Anti-death properties of TNF against metabolic poisoning: mitochondrial stabilization by MnSOD.
Journal of neuroimmunology 1999;93(1-2):53-71.
1999: Pedersen W A; Cashman N R; Mattson M P
The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells.
Experimental neurology 1999;155(1):1-10.
1999: Bruce-Keller A J; Umberger G; McFall R; Mattson M P
Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults.
Annals of neurology 1999;45(1):8-15.
1999: Wernyj R P; Mattson M P; Christakos S
Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid beta-peptide.
Brain research. Molecular brain research 1999;64(1):69-79.
1999: Guo Q; Fu W; Sopher B L; Miller M W; Ware C B; Martin G M; Mattson M P
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
Nature medicine 1999;5(1):101-6.
1999: Opanashuk L A; Mark R J; Porter J; Damm D; Mattson M P; Seroogy K B
Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(1):133-46.
1999: Mattson M P; Pedersen W A; Duan W; Culmsee C; Camandola S
Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.
Annals of the New York Academy of Sciences 1999;893():154-75.
1999: Mattson M P
Impairment of membrane transport and signal transduction systems by amyloidogenic proteins.
Methods in enzymology 1999;309():733-46.
1998: Kruman I I; Nath A; Mattson M P
HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress.
Experimental neurology 1998;154(2):276-88.
1998: Gary D S; Bruce-Keller A J; Kindy M S; Mattson M P
Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(12):1283-7.
1998: Mattson M P; Pedersen W A
Effects of amyloid precursor protein derivatives and oxidative stress on basal forebrain cholinergic systems in Alzheimer's disease.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1998;16(7-8):737-53.
1998: Keller J N; Hanni K B; Mattson M P; Markesbery W R
Cyclic nucleotides attenuate lipid peroxidation-mediated neuron toxicity.
Neuroreport 1998;9(16):3731-4.
1998: Pedersen W A; Fu W; Keller J N; Markesbery W R; Appel S; Smith R G; Kasarskis E; Mattson M P
Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients.
Annals of neurology 1998;44(5):819-24.
1998: Fu W; Luo H; Parthasarathy S; Mattson M P
Catecholamines potentiate amyloid beta-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis.
Neurobiology of disease 1998;5(4):229-43.
1998: Sullivan P G; Keller J N; Mattson M P; Scheff S W
Traumatic brain injury alters synaptic homeostasis: implications for impaired mitochondrial and transport function.
Journal of neurotrauma 1998;15(10):789-98.
1998: Smith R G; Henry Y K; Mattson M P; Appel S H
Presence of 4-hydroxynonenal in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis.
Annals of neurology 1998;44(4):696-9.
1998: Mattson M P; Partin J; Begley J G
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites.
Brain research 1998;807(1-2):167-76.
1998: Begley J G; Butterfield D A; Keller J N; Koppal T; Drake J; Mattson M P
Cryopreservation of rat cortical synaptosomes and analysis of glucose and glutamate transporter activities, and mitochondrial function.
Brain research. Brain research protocols 1998;3(1):76-82.
1998: Holtsberg F W; Steiner M R; Bruce-Keller A J; Keller J N; Mattson M P; Moyers J C; Steiner S M
Lysophosphatidic acid and apoptosis of nerve growth factor-differentiated PC12 cells.
Journal of neuroscience research 1998;53(6):685-96.
1998: Mattson M P; Keller J N; Begley J G
Evidence for synaptic apoptosis.
Experimental neurology 1998;153(1):35-48.
1998: Yu Z F; Bruce-Keller A J; Goodman Y; Mattson M P
Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo.
Journal of neuroscience research 1998;53(5):613-25.
1998: Guo Q; Fu W; Xie J; Luo H; Sells S F; Geddes J W; Bondada V; Rangnekar V M; Mattson M P
Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.
Nature medicine 1998;4(8):957-62.
1998: Furukawa K; Guo Q; Schellenberg G D; Mattson M P
Presenilin-1 mutation alters NGF-induced neurite outgrowth, calcium homeostasis, and transcription factor (AP-1) activation in PC12 cells.
Journal of neuroscience research 1998;52(5):618-24.
1998: Keller J N; Guo Q; Holtsberg F W; Bruce-Keller A J; Mattson M P
Increased sensitivity to mitochondrial toxin-induced apoptosis in neural cells expressing mutant presenilin-1 is linked to perturbed calcium homeostasis and enhanced oxyradical production.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(12):4439-50.
1998: Masliah E; Raber J; Alford M; Mallory M; Mattson M P; Yang D; Wong D; Mucke L
Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis.
The Journal of biological chemistry 1998;273(20):12548-54.
1998: Guo Q; Robinson N; Mattson M P
Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis.
The Journal of biological chemistry 1998;273(20):12341-51.
1998: Furukawa K; Mattson M P
The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.
Journal of neurochemistry 1998;70(5):1876-86.
1998: Majima H J; Oberley T D; Furukawa K; Mattson M P; Yen H C; Szweda L I; St Clair D K
Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death.
The Journal of biological chemistry 1998;273(14):8217-24.
1998: Bruce-Keller A J; Li Y J; Lovell M A; Kraemer P J; Gary D S; Brown R R; Markesbery W R; Mattson M P
4-Hydroxynonenal, a product of lipid peroxidation, damages cholinergic neurons and impairs visuospatial memory in rats.
Journal of neuropathology and experimental neurology 1998;57(3):257-67.
1998: Guo Q; Christakos S; Robinson N; Mattson M P
Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3227-32.
1998: Blanc E M; Bruce-Keller A J; Mattson M P
Astrocytic gap junctional communication decreases neuronal vulnerability to oxidative stress-induced disruption of Ca2+ homeostasis and cell death.
Journal of neurochemistry 1998;70(3):958-70.
1998: Furukawa K; Mattson M P
Secreted amyloid precursor protein alpha selectively suppresses N-methyl-D-aspartate currents in hippocampal neurons: involvement of cyclic GMP.
Neuroscience 1998;83(2):429-38.
1998: Blanc E M; Keller J N; Fernandez S; Mattson M P
4-hydroxynonenal, a lipid peroxidation product, impairs glutamate transport in cortical astrocytes.
Glia 1998;22(2):149-60.
1998: Mattson M P
Modification of ion homeostasis by lipid peroxidation: roles in neuronal degeneration and adaptive plasticity.
Trends in neurosciences 1998;21(2):53-7.
1998: Kruman I; Guo Q; Mattson M P
Calcium and reactive oxygen species mediate staurosporine-induced mitochondrial dysfunction and apoptosis in PC12 cells.
Journal of neuroscience research 1998;51(3):293-308.
1998: Keller J N; Kindy M S; Holtsberg F W; St Clair D K; Yen H C; Germeyer A; Steiner S M; Bruce-Keller A J; Hutchins J B; Mattson M P
Mitochondrial manganese superoxide dismutase prevents neural apoptosis and reduces ischemic brain injury: suppression of peroxynitrite production, lipid peroxidation, and mitochondrial dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(2):687-97.
1998: Holtsberg F W; Steiner M R; Keller J N; Mark R J; Mattson M P; Steiner S M
Lysophosphatidic acid induces necrosis and apoptosis in hippocampal neurons.
Journal of neurochemistry 1998;70(1):66-76.
1998: Bruce-Keller A J; Begley J G; Fu W; Butterfield D A; Bredesen D E; Hutchins J B; Hensley K; Mattson M P
Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide.
Journal of neurochemistry 1998;70(1):31-9.
1998: Mattson M P; Guo Q; Furukawa K; Pedersen W A
Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.
Journal of neurochemistry 1998;70(1):1-14.
1998: Mattson M P; Furukawa K
Signaling events regulating the neurodevelopmental triad. Glutamate and secreted forms of beta-amyloid precursor protein as examples.
Perspectives on developmental neurobiology 1998;5(4):337-52.
1998: Keller J N; Mattson M P
Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system.
Reviews in the neurosciences 1998;9(2):105-16.
1998: Mattson M P
Free radicals, calcium, and the synaptic plasticity-cell death continuum: emerging roles of the transcription factor NF kappa B.
International review of neurobiology 1998;42():103-68.
1997: Mattson M P; Robinson N; Guo Q
Estrogens stabilize mitochondrial function and protect neural cells against the pro-apoptotic action of mutant presenilin-1.
Neuroreport 1997;8(17):3817-21.
1997: Keller J N; Germeyer A; Begley J G; Mattson M P
17Beta-estradiol attenuates oxidative impairment of synaptic Na+/K+-ATPase activity, glucose transport, and glutamate transport induced by amyloid beta-peptide and iron.
Journal of neuroscience research 1997;50(4):522-30.
1997: Mattson M P; Guo Q
Cell and molecular neurobiology of presenilins: a role for the endoplasmic reticulum in the pathogenesis of Alzheimer's disease?
Journal of neuroscience research 1997;50(4):505-13.
1997: Mattson M P
Advances fuel Alzheimer's conundrum.
Nature genetics 1997;17(3):254-6.
1997: Furukawa K; Fu W; Li Y; Witke W; Kwiatkowski D J; Mattson M P
The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8178-86.
1997: Mattson M P; Begley J G; Mark R J; Furukawa K
Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms.
Brain research 1997;771(1):147-53.
1997: Toborek M; Blanc E M; Kaiser S; Mattson M P; Hennig B
Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells.
Journal of lipid research 1997;38(10):2155-67.
1997: Mattson M P
Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives.
Physiological reviews 1997;77(4):1081-132.
1997: Keller J N; Mark R J; Bruce A J; Blanc E; Rothstein J D; Uchida K; Waeg G; Mattson M P
4-Hydroxynonenal, an aldehydic product of membrane lipid peroxidation, impairs glutamate transport and mitochondrial function in synaptosomes.
Neuroscience 1997;80(3):685-96.
1997: Lovell M A; Ehmann W D; Mattson M P; Markesbery W R
Elevated 4-hydroxynonenal in ventricular fluid in Alzheimer's disease.
Neurobiology of aging 1997;18(5):457-61.
1997: Mattson M P; Goodman Y; Luo H; Fu W; Furukawa K
Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.
Journal of neuroscience research 1997;49(6):681-97.
1997: Mattson M P
Mother's legacy: mitochondrial DNA mutations and Alzheimer's disease.
Trends in neurosciences 1997;20(9):373-5.
1997: Subramaniam R; Roediger F; Jordan B; Mattson M P; Keller J N; Waeg G; Butterfield D A
The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins.
Journal of neurochemistry 1997;69(3):1161-9.
1997: Keller J N; Steiner M R; Holtsberg F W; Mattson M P; Steiner S M
Lysophosphatidic acid-induced proliferation-related signals in astrocytes.
Journal of neurochemistry 1997;69(3):1073-84.
1997: Pedersen W A; Guo Q; Hartman B K; Mattson M P
Nerve growth factor-independent reduction in choline acetyltransferase activity in PC12 cells expressing mutant presenilin-1.
The Journal of biological chemistry 1997;272(36):22397-400.
1997: Azbill R D; Mu X; Bruce-Keller A J; Mattson M P; Springer J E
Impaired mitochondrial function, oxidative stress and altered antioxidant enzyme activities following traumatic spinal cord injury.
Brain research 1997;765(2):283-90.
1997: Blanc E M; Kelly J F; Mark R J; Waeg G; Mattson M P
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Journal of neurochemistry 1997;69(2):570-80.
1997: Mattson M P; Fu W; Waeg G; Uchida K
4-Hydroxynonenal, a product of lipid peroxidation, inhibits dephosphorylation of the microtubule-associated protein tau.
Neuroreport 1997;8(9-10):2275-81.
1997: Ishida A; Furukawa K; Keller J N; Mattson M P
Secreted form of beta-amyloid precursor protein shifts the frequency dependency for induction of LTD, and enhances LTP in hippocampal slices.
Neuroreport 1997;8(9-10):2133-7.
1997: Lee S; Williamson J; Lothman E W; Szele F G; Chesselet M F; Von Hagen S; Sapolsky R M; Mattson M P; Christakos S
Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment.
Brain research. Molecular brain research 1997;47(1-2):183-94.
1997: Keller J N; Pang Z; Geddes J W; Begley J G; Germeyer A; Waeg G; Mattson M P
Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid beta-peptide: role of the lipid peroxidation product 4-hydroxynonenal.
Journal of neurochemistry 1997;69(1):273-84.
1997: Holtsberg F W; Steiner M R; Furukawa K; Keller J N; Mattson M P; Steiner S M
Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium.
Journal of neurochemistry 1997;69(1):68-75.
1997: Barger S W; Mattson M P
Isoform-specific modulation by apolipoprotein E of the activities of secreted beta-amyloid precursor protein.
Journal of neurochemistry 1997;69(1):60-7.
1997: Sells S F; Han S S; Muthukkumar S; Maddiwar N; Johnstone R; Boghaert E; Gillis D; Liu G; Nair P; Monnig S; Collini P; Mattson M P; Sukhatme V P; Zimmer S G; Wood D P; McRoberts J W; Shi Y; Rangnekar V M
Expression and function of the leucine zipper protein Par-4 in apoptosis.
Molecular and cellular biology 1997;17(7):3823-32.
1997: Kruman I; Bruce-Keller A J; Bredesen D; Waeg G; Mattson M P
Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(13):5089-100.
1997: Springer J E; Azbill R D; Mark R J; Begley J G; Waeg G; Mattson M P
4-hydroxynonenal, a lipid peroxidation product, rapidly accumulates following traumatic spinal cord injury and inhibits glutamate uptake.
Journal of neurochemistry 1997;68(6):2469-76.
1997: Guo Q; Sopher B L; Furukawa K; Pham D G; Robinson N; Martin G M; Mattson M P
Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(11):4212-22.
1997: Aziz S M; Toborek M; Hennig B; Mattson M P; Guo H; Lipke D W
Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells.
The international journal of biochemistry & cell biology 1997;29(5):775-87.
1997: Mark R J; Keller J N; Kruman I; Mattson M P
Basic FGF attenuates amyloid beta-peptide-induced oxidative stress, mitochondrial dysfunction, and impairment of Na+/K+-ATPase activity in hippocampal neurons.
Brain research 1997;756(1-2):205-14.
1997: Mattson M P; Mark R J; Furukawa K; Bruce A J
Disruption of brain cell ion homeostasis in Alzheimer's disease by oxy radicals, and signaling pathways that protect therefrom.
Chemical research in toxicology 1997;10(5):507-17.
1997: Mattson M P; Furukawa K
Alzheimer's disease. Short precursor shortens memory.
Nature 1997;387(6632):457-8.
1997: Blanc E M; Toborek M; Mark R J; Hennig B; Mattson M P
Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells.
Journal of neurochemistry 1997;68(5):1870-81.
1997: Mattson M P
Neuroprotective signal transduction: relevance to stroke.
Neuroscience and biobehavioral reviews 1997;21(2):193-206.
1997: Furukawa K; Estus S; Fu W; Mark R J; Mattson M P
Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways.
The Journal of cell biology 1997;136(5):1137-49.
1997: Mattson M P; Barger S W; Furukawa K; Bruce A J; Wyss-Coray T; Mark R J; Mucke L
Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease.
Brain research. Brain research reviews 1997;23(1-2):47-61.
1997: Mark R J; Pang Z; Geddes J W; Uchida K; Mattson M P
Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(3):1046-54.
1997: Mark R J; Lovell M A; Markesbery W R; Uchida K; Mattson M P
A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.
Journal of neurochemistry 1997;68(1):255-64.
1997: Mattson M P; Furukawa K
Anti-apoptotic actions of cycloheximide: blockade of programmed cell death or induction of programmed cell life?
Apoptosis : an international journal on programmed cell death 1997;2(3):257-64.
1996: Guo Q; Furukawa K; Sopher B L; Pham D G; Xie J; Robinson N; Martin G M; Mattson M P
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide.
Neuroreport 1996;8(1):379-83.
1996: Xie C X; Mattson M P; Lovell M A; Yokel R A
Intraneuronal aluminum potentiates iron-induced oxidative stress in cultured rat hippocampal neurons.
Brain research 1996;743(1-2):271-7.
1996: Keller J N; Steiner M R; Mattson M P; Steiner S M
Lysophosphatidic acid decreases glutamate and glucose uptake by astrocytes.
Journal of neurochemistry 1996;67(6):2300-5.
1996: Furukawa K; Sopher B L; Rydel R E; Begley J G; Pham D G; Martin G M; Fox M; Mattson M P
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain.
Journal of neurochemistry 1996;67(5):1882-96.
1996: Smith-Swintosky V L; Kraemer P J; Bruce A J; McCants N; Maki A; Brown R W; Alcala M; Goodman Y; Slevin J T; Mattson M P
Bacterial alkaloids mitigate seizure-induced hippocampal damage and spatial memory deficits.
Experimental neurology 1996;141(2):287-96.
1996: Barger S W; Mattson M P
Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.
Brain research. Molecular brain research 1996;40(1):116-26.
1996: Mattson M P; Rydel R E
Alzheimer's disease. Amyloid ox-tox transducers.
Nature 1996;382(6593):674-5.
1996: Smith-Swintosky V L; Pettigrew L C; Sapolsky R M; Phares C; Craddock S D; Brooke S M; Mattson M P
Metyrapone, an inhibitor of glucocorticoid production, reduces brain injury induced by focal and global ischemia and seizures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):585-98.
1996: Bruce A J; Boling W; Kindy M S; Peschon J; Kraemer P J; Carpenter M K; Holtsberg F W; Mattson M P
Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors.
Nature medicine 1996;2(7):788-94.
1996: Mark R J; Blanc E M; Mattson M P
Amyloid beta-peptide and oxidative cellular injury in Alzheimer's disease.
Molecular neurobiology 1996;12(3):211-24.
1996: Kelly J F; Furukawa K; Barger S W; Rengen M R; Mark R J; Blanc E M; Roth G S; Mattson M P
Amyloid beta-peptide disrupts carbachol-induced muscarinic cholinergic signal transduction in cortical neurons.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6753-8.
1996: Hensley K; Butterfield D A; Hall N; Cole P; Subramaniam R; Mark R; Mattson M P; Markesbery W R; Harris M E; Aksenov M
Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide.
Annals of the New York Academy of Sciences 1996;786():120-34.
1996: Hauser K F; Stiene-Martin A; Mattson M P; Elde R P; Ryan S E; Godleske C C
mu-Opioid receptor-induced Ca2+ mobilization and astroglial development: morphine inhibits DNA synthesis and stimulates cellular hypertrophy through a Ca(2+)-dependent mechanism.
Brain research 1996;720(1-2):191-203.
1996: Goodman Y; Bruce A J; Cheng B; Mattson M P
Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons.
Journal of neurochemistry 1996;66(5):1836-44.
1996: Mattson M P; Bruce A J; Blanc E M
Elusive roles for astrocytes in neurodegenerative disorders.
Neurobiology of aging 1996;17(3):485-7; discussion 488-90.
1996: Padmaperuma B; Mark R; Dhillon H S; Mattson M P; Prasad M R
Alterations in brain protein kinase C after experimental brain injury.
Brain research 1996;714(1-2):19-26.
1996: McMahon D G; Mattson M P
Horizontal cell electrical coupling in the giant danio: synaptic modulation by dopamine and synaptic maintenance by calcium.
Brain research 1996;718(1-2):89-96.
1996: Hennig B; Toborek M; Joshi-Barve S; Barger S W; Barve S; Mattson M P; McClain C J
Linoleic acid activates nuclear transcription factor-kappa B (NF-kappa B) and induces NF-kappa B-dependent transcription in cultured endothelial cells.
The American journal of clinical nutrition 1996;63(3):322-8.
1996: Goodman Y; Mattson M P
Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity.
Journal of neurochemistry 1996;66(2):869-72.
1996: Goodman Y; Mattson M P
K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity.
Brain research 1996;706(2):328-32.
1996: Toborek M; Barger S W; Mattson M P; Barve S; McClain C J; Hennig B
Linoleic acid and TNF-alpha cross-amplify oxidative injury and dysfunction of endothelial cells.
Journal of lipid research 1996;37(1):123-35.
1996: Barger S W; Mattson M P
Participation of gene expression in the protection against amyloid beta-peptide toxicity by the beta-amyloid precursor protein.
Annals of the New York Academy of Sciences 1996;777():303-9.
1996: Furukawa K; Barger S W; Blalock E M; Mattson M P
Activation of K+ channels and suppression of neuronal activity by secreted beta-amyloid-precursor protein.
Nature 1996;379(6560):74-8.
1996: Mattson M P
Calcium and Free Radicals: Mediators of neurotrophic factor and excitatory transmitter-regulated developmental plasticity and cell death.
Perspectives on developmental neurobiology 1996;3(2):79-91.
1996: Mattson M P; Mark R J
Excitotoxicity and excitoprotection in vitro.
Advances in neurology 1996;71():1-30; discussion 30-5.
1995: Cheng B; Furukawa K; O'Keefe J A; Goodman Y; Kihiko M; Fabian T; Mattson M P
Basic fibroblast growth factor selectively increases AMPA-receptor subunit GluR1 protein level and differentially modulates Ca2+ responses to AMPA and NMDA in hippocampal neurons.
Journal of neurochemistry 1995;65(6):2525-36.
1995: Mattson M P
Untangling the pathophysiochemistry of beta-amyloid.
Nature structural biology 1995;2(11):926-8.
1995: Cheng B; Mattson M P
PDGFs protect hippocampal neurons against energy deprivation and oxidative injury: evidence for induction of antioxidant pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7095-104.
1995: Toborek M; Barger S W; Mattson M P; McClain C J; Hennig B
Role of glutathione redox cycle in TNF-alpha-mediated endothelial cell dysfunction.
Atherosclerosis 1995;117(2):179-88.
1995: Mattson M P; Cheng B; Baldwin S A; Smith-Swintosky V L; Keller J; Geddes J W; Scheff S W; Christakos S
Brain injury and tumor necrosis factors induce calbindin D-28k in astrocytes: evidence for a cytoprotective response.
Journal of neuroscience research 1995;42(3):357-70.
1995: Barger S W; Mattson M P
The secreted form of the Alzheimer's beta-amyloid precursor protein stimulates a membrane-associated guanylate cyclase.
The Biochemical journal 1995;311 ( Pt 1)():45-7.
1995: Mattson M P; Lovell M A; Furukawa K; Markesbery W R
Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons.
Journal of neurochemistry 1995;65(4):1740-51.
1995: Mark R J; Hensley K; Butterfield D A; Mattson M P
Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(9):6239-49.
1995: Smith-Swintosky V L; Zimmer S; Fenton J W; Mattson M P
Opposing actions of thrombin and protease nexin-1 on amyloid beta-peptide toxicity and on accumulation of peroxides and calcium in hippocampal neurons.
Journal of neurochemistry 1995;65(3):1415-8.
1995: Furukawa K; Mattson M P
Cytochalasins protect hippocampal neurons against amyloid beta-peptide toxicity: evidence that actin depolymerization suppresses Ca2+ influx.
Journal of neurochemistry 1995;65(3):1061-8.
1995: Barger S W; Hörster D; Furukawa K; Goodman Y; Krieglstein J; Mattson M P
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9328-32.
1995: Toborek M; Barger S W; Mattson M P; Espandiari P; Robertson L W; Hennig B
Exposure to polychlorinated biphenyls causes endothelial cell dysfunction.
Journal of biochemical toxicology 1995;10(4):219-26.
1995: Furukawa K; Mattson M P
Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity.
Brain research 1995;689(1):141-6.
1995: Smith-Swintosky V L; Zimmer S; Fenton J W; Mattson M P
Protease nexin-1 and thrombin modulate neuronal Ca2+ homeostasis and sensitivity to glucose deprivation-induced injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(8):5840-50.
1995: Mattson M P
Free radicals and disruption of neuronal ion homeostasis in AD: a role for amyloid beta-peptide?
Neurobiology of aging 1995;16(4):679-82; discussion 683.
1995: Furukawa K; Smith-Swintosky V L; Mattson M P
Evidence that actin depolymerization protects hippocampal neurons against excitotoxicity by stabilizing [Ca2+]i.
Experimental neurology 1995;133(2):153-63.
1995: Barger S W; Fiscus R R; Ruth P; Hofmann F; Mattson M P
Role of cyclic GMP in the regulation of neuronal calcium and survival by secreted forms of beta-amyloid precursor.
Journal of neurochemistry 1995;64(5):2087-96.
1995: Mattson M P
Degenerative and protective signaling mechanisms in the neurofibrillary pathology of AD.
Neurobiology of aging 1995;16(3):447-57; discussion 458-63.
1995: Mattson M P; Goodman Y
Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium.
Brain research 1995;676(1):219-24.
1995: Barger S W; Van Eldik L J; Mattson M P
S100 beta protects hippocampal neurons from damage induced by glucose deprivation.
Brain research 1995;677(1):167-70.
1995: Mark R J; Ashford J W; Goodman Y; Mattson M P
Anticonvulsants attenuate amyloid beta-peptide neurotoxicity, Ca2+ deregulation, and cytoskeletal pathology.
Neurobiology of aging 1995;16(2):187-98.
1995: Mattson M P; Carney J W; Butterfield D A
A tombstone in Alzheimer's?
Nature 1995;373(6514):481.
1995: Mattson M P; Barger S W; Begley J G; Mark R J
Calcium, free radicals, and excitotoxic neuronal death in primary cell culture.
Methods in cell biology 1995;46():187-216.
1995: Hensley K; Butterfield D A; Mattson M; Aksenova M; Harris M; Wu J F; Floyd R; Carney J
A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease.
Proceedings of the Western Pharmacology Society 1995;38():113-20.
1994: Mattson M P
Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise.
Annals of the New York Academy of Sciences 1994;747():50-76.
1994: Stein-Behrens B; Mattson M P; Chang I; Yeh M; Sapolsky R
Stress exacerbates neuron loss and cytoskeletal pathology in the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(9):5373-80.
1994: Smith-Swintosky V L; Pettigrew L C; Craddock S D; Culwell A R; Rydel R E; Mattson M P
Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury.
Journal of neurochemistry 1994;63(2):781-4.
1994: Goodman Y; Steiner M R; Steiner S M; Mattson M P
Nordihydroguaiaretic acid protects hippocampal neurons against amyloid beta-peptide toxicity, and attenuates free radical and calcium accumulation.
Brain research 1994;654(1):171-6.
1994: Goodman Y; Mattson M P
Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.
Experimental neurology 1994;128(1):1-12.
1994: Cheng B; Goodman Y; Begley J G; Mattson M P
Neurotrophin-4/5 protects hippocampal and cortical neurons against energy deprivation- and excitatory amino acid-induced injury.
Brain research 1994;650(2):331-5.
1994: Goodman Y; Mattson M P
Staurosporine and K-252 compounds protect hippocampal neurons against amyloid beta-peptide toxicity and oxidative injury.
Brain research 1994;650(1):170-4.
1994: Butterfield D A; Hensley K; Harris M; Mattson M; Carney J
beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.
Biochemical and biophysical research communications 1994;200(2):710-5.
1994: Hensley K; Carney J M; Mattson M P; Aksenova M; Harris M; Wu J F; Floyd R A; Butterfield D A
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3270-4.
1994: Mattson M P
Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons.
Journal of neurobiology 1994;25(4):439-50.
1994: Cheng B; Barger S W; Mattson M P
Staurosporine, K-252a, and K-252b stabilize calcium homeostasis and promote survival of CNS neurons in the absence of glucose.
Journal of neurochemistry 1994;62(4):1319-29.
1994: Cheng B; Mattson M P
NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults.
Brain research 1994;640(1-2):56-67.
1994: Mattson M P; Scheff S W
Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy.
Journal of neurotrauma 1994;11(1):3-33.
1994: Cheng B; Christakos S; Mattson M P
Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis.
Neuron 1994;12(1):139-53.
1994: Smith-Swintosky V L; Mattson M P
Glutamate, beta-amyloid precursor proteins, and calcium mediated neurofibrillary degeneration.
Journal of neural transmission. Supplementum 1994;44():29-45.
1994: Mattson M P
Mechanism of neuronal degeneration and preventative approaches: quickening the pace of AD research.
Neurobiology of aging 1994;15 Suppl 2():S121-5.
1993: Mattson M P; Cheng B
Growth factors protect neurons against excitotoxic/ischemic damage by stabilizing calcium homeostasis.
Stroke; a journal of cerebral circulation 1993;24(12 Suppl):I136-40; discussion I144-5.
1993: Stiene-Martin A; Mattson M P; Hauser K F
Opiates selectively increase intracellular calcium in developing type-1 astrocytes: role of calcium in morphine-induced morphologic differentiation.
Brain research. Developmental brain research 1993;76(2):189-96.
1993: Mattson M P; Cheng B; Smith-Swintosky V L
Mechanisms of neurotrophic factor protection against calcium- and free radical-mediated excitotoxic injury: implications for treating neurodegenerative disorders.
Experimental neurology 1993;124(1):89-95.
1993: Mattson M P; Kumar K N; Wang H; Cheng B; Michaelis E K
Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(11):4575-88.
1993: Mattson M P; Barger S W; Cheng B; Lieberburg I; Smith-Swintosky V L; Rydel R E
beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.
Trends in neurosciences 1993;16(10):409-14.
1993: Barger S W; Smith-Swintosky V L; Rydel R E; Mattson M P
beta-Amyloid precursor protein mismetabolism and loss of calcium homeostasis in Alzheimer's disease.
Annals of the New York Academy of Sciences 1993;695():158-64.
1993: Mattson M P; Tomaselli K J; Rydel R E
Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.
Brain research 1993;621(1):35-49.
1993: Elliott E M; Mattson M P; Vanderklish P; Lynch G; Chang I; Sapolsky R M
Corticosterone exacerbates kainate-induced alterations in hippocampal tau immunoreactivity and spectrin proteolysis in vivo.
Journal of neurochemistry 1993;61(1):57-67.
1993: Mattson M P; Rydel R E; Lieberburg I; Smith-Swintosky V L
Altered calcium signaling and neuronal injury: stroke and Alzheimer's disease as examples.
Annals of the New York Academy of Sciences 1993;679():1-21.
1993: Mattson M P; Zhang Y; Bose S
Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose.
Experimental neurology 1993;121(1):1-13.
1993: Zhang Y; Tatsuno T; Carney J M; Mattson M P
Basic FGF, NGF, and IGFs protect hippocampal and cortical neurons against iron-induced degeneration.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(3):378-88.
1993: Cheng B; McMahon D G; Mattson M P
Modulation of calcium current, intracellular calcium levels and cell survival by glucose deprivation and growth factors in hippocampal neurons.
Brain research 1993;607(1-2):275-85.
1993: Mattson M P; Cheng B; Culwell A R; Esch F S; Lieberburg I; Rydel R E
Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.
Neuron 1993;10(2):243-54.
1993: Mattson M P; Lovell M A; Ehmann W D; Markesbery W R
Comparison of the effects of elevated intracellular aluminum and calcium levels on neuronal survival and tau immunoreactivity.
Brain research 1993;602(1):21-31.
1993: Mattson M P; Barger S W
Roles for calcium signaling in structural plasticity and pathology in the hippocampal system.
Hippocampus 1993;3 Spec No():73-87.
1992: Mattson M P; Rydel R E
beta-Amyloid precursor protein and Alzheimer's disease: the peptide plot thickens.
Neurobiology of aging 1992;13(5):617-21.
1992: Cheng B; Mattson M P
Glucose deprivation elicits neurofibrillary tangle-like antigenic changes in hippocampal neurons: prevention by NGF and bFGF.
Experimental neurology 1992;117(2):114-23.
1992: Mattson M P
Effects of microtubule stabilization and destabilization on tau immunoreactivity in cultured hippocampal neurons.
Brain research 1992;582(1):107-18.
1992: Cheng B; Mattson M P
IGF-I and IGF-II protect cultured hippocampal and septal neurons against calcium-mediated hypoglycemic damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(4):1558-66.
1992: Mattson M P; Rychlik B; Cheng B
Degenerative and axon outgrowth-altering effects of phencyclidine in human fetal cerebral cortical cells.
Neuropharmacology 1992;31(3):279-91.
1992: Mattson M P; Cheng B; Davis D; Bryant K; Lieberburg I; Rydel R E
beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(2):376-89.
1992: Mattson M P
Calcium as sculptor and destroyer of neural circuitry.
Experimental gerontology 1992;27(1):29-49.
1991: Cheng B; Mattson M P
NGF and bFGF protect rat hippocampal and human cortical neurons against hypoglycemic damage by stabilizing calcium homeostasis.
Neuron 1991;7(6):1031-41.
1991: Mattson M P; Wang H; Michaelis E K
Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons.
Brain research 1991;565(1):94-108.
1991: Mattson M P; Rychlik B
Comparison of rates of neuronal development and survival in human and rat cerebral cortical cell cultures.
Mechanisms of ageing and development 1991;60(2):171-87.
1991: Mattson M P; Engle M G; Rychlik B
Effects of elevated intracellular calcium levels on the cytoskeleton and tau in cultured human cortical neurons.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1991;15(2):117-42.
1991: Mattson M P
Activities in cellular signalling pathways: a two-edged sword?
Neurobiology of aging 1991;12(4):343-6; discussion 352-5.
1991: Mattson M P
Evidence for the involvement of protein kinase C in neurodegenerative changes in cultured human cortical neurons.
Experimental neurology 1991;112(1):95-103.
1991: Mattson M P; Rychlik B; You J S; Sisken J E
Sensitivity of cultured human embryonic cerebral cortical neurons to excitatory amino acid-induced calcium influx and neurotoxicity.
Brain research 1991;542(1):97-106.
1991: Mattson M P; Rychlik B; Chu C; Christakos S
Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons.
Neuron 1991;6(1):41-51.
1990: Mattson M P; Rychlik B
Cell culture of cryopreserved human fetal cerebral cortical and hippocampal neurons: neuronal development and responses to trophic factors.
Brain research 1990;522(2):204-14.
1990: Mattson M P; Murain M; Guthrie P B
Localized calcium influx orients axon formation in embryonic hippocampal pyramidal neurons.
Brain research. Developmental brain research 1990;52(1-2):201-9.
1990: Mattson M P
Antigenic changes similar to those seen in neurofibrillary tangles are elicited by glutamate and Ca2+ influx in cultured hippocampal neurons.
Neuron 1990;4(1):105-17.
1990: Mattson M P; Rychlik B
Glia protect hippocampal neurons against excitatory amino acid-induced degeneration: involvement of fibroblast growth factor.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1990;8(4):399-415.
1990: Mattson M P
Excitatory amino acids, growth factors, and calcium: a teeter-totter model for neural plasticity and degeneration.
Advances in experimental medicine and biology 1990;268():211-20.
1989: Mattson M P; Murrain M; Guthrie P B; Kater S B
Fibroblast growth factor and glutamate: opposing roles in the generation and degeneration of hippocampal neuroarchitecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(11):3728-40.
1989: Mattson M P; Guthrie P B; Kater S B
A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(13):2519-26.
1989: Mattson M P
Cellular signaling mechanisms common to the development and degeneration of neuroarchitecture. A review.
Mechanisms of ageing and development 1989;50(2):103-57.
1989: Wiltbank M C; Guthrie P B; Mattson M P; Kater S B; Niswender G D
Hormonal regulation of free intracellular calcium concentrations in small and large ovine luteal cells.
Biology of reproduction 1989;41(4):771-8.
1989: Mattson M P
Acetylcholine potentiates glutamate-induced neurodegeneration in cultured hippocampal neurons.
Brain research 1989;497(2):402-6.
1989: Mattson M P; Kater S B
Development and selective neurodegeneration in cell cultures from different hippocampal regions.
Brain research 1989;490(1):110-25.
1989: Mattson M P; Guthrie P B; Hayes B C; Kater S B
Roles for mitotic history in the generation and degeneration of hippocampal neuroarchitecture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(4):1223-32.
1989: Mattson M P; Kater S B
Excitatory and inhibitory neurotransmitters in the generation and degeneration of hippocampal neuroarchitecture.
Brain research 1989;478(2):337-48.
1989: Mattson M P; Guthrie P B; Kater S B
Intrinsic factors in the selective vulnerability of hippocampal pyramidal neurons.
Progress in clinical and biological research 1989;317():333-51.
1989: Kater S B; Mattson M P; Guthrie P B
Calcium-induced neuronal degeneration: a normal growth cone regulating signal gone awry (?).
Annals of the New York Academy of Sciences 1989;568():252-61.
1988: Mattson M P; Lee R E; Adams M E; Guthrie P B; Kater S B
Interactions between entorhinal axons and target hippocampal neurons: a role for glutamate in the development of hippocampal circuitry.
Neuron 1988;1(9):865-76.
1988: Mattson M P; Guthrie P B; Kater S B
Intracellular messengers in the generation and degeneration of hippocampal neuroarchitecture.
Journal of neuroscience research 1988;21(2-4):447-64.
1988: Mattson M P; Guthrie P B; Kater S B
Components of neurite outgrowth that determine neuronal cytoarchitecture: influence of calcium and the growth substrate.
Journal of neuroscience research 1988;20(3):331-45.
1988: Kater S B; Mattson M P; Cohan C; Connor J
Calcium regulation of the neuronal growth cone.
Trends in neurosciences 1988;11(7):315-21.
1988: Mattson M P; Dou P; Kater S B
Outgrowth-regulating actions of glutamate in isolated hippocampal pyramidal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(6):2087-100.
1988: Mattson M P; Taylor-Hunter A; Kater S B
Neurite outgrowth in individual neurons of a neuronal population is differentially regulated by calcium and cyclic AMP.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(5):1704-11.
1988: Mattson M P; Kater S B
Fibronectin-like immunoreactivity in Helisoma buccal ganglia: evidence that an endogenous fibronectin-like molecule promotes neurite outgrowth.
Journal of neurobiology 1988;19(3):239-56.
1988: Mattson M P
Neurotransmitters in the regulation of neuronal cytoarchitecture.
Brain research 1988;472(2):179-212.
1988: Mattson M P; Kater S B
Isolated hippocampal neurons in cryopreserved long-term cultures: development of neuroarchitecture and sensitivity to NMDA.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1988;6(5):439-52.
1987: Mattson M P; Kater S B
Calcium regulation of neurite elongation and growth cone motility.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(12):4034-43.
1987: Mattson M P; Spaziani E
Demonstration of protein kinase C activity in crustacean Y-organs, and partial definition of its role in regulation of ecdysteroidogenesis.
Molecular and cellular endocrinology 1987;49(2-3):159-71.
1986: Mattson M P; Spaziani E
Regulation of crab Y-organ steroidogenesis in vitro: evidence that ecdysteroid production increases through activation of cAMP-phosphodiesterase by calcium-calmodulin.
Molecular and cellular endocrinology 1986;48(2-3):135-51.
1986: Mattson M P; Spaziani E
Regulation of Y-organ ecdysteroidogenesis by molt-inhibiting hormone in crabs: involvement of cyclic AMP-mediated protein synthesis.
General and comparative endocrinology 1986;63(3):414-23.
1986: Mattson M P; Spaziani E
Regulation of the stress-responsive X-organ--Y-organ axis by 5-hydroxytryptamine in the crab, Cancer antennarius.
General and comparative endocrinology 1986;62(3):419-27.
1985: Mattson M P; Spaziani E
Characterization of molt-inhibiting hormone (MIH) action on crustacean Y-organ segments and dispersed cells in culture and a bioassay for MIH activity.
The Journal of experimental zoology 1985;236(1):93-101.
1985: Mattson M P; Spaziani E
Cyclic AMP mediates the negative regulation of Y-organ ecdysteroid production.
Molecular and cellular endocrinology 1985;42(2):185-9.
1985: Mattson M P; Mrotek J J
Exogenous steroids alter steroidogenesis in cultured Y-1 adrenal tumor cells by actions preceding cyclic AMP.
Steroids 1985;46(1):619-37.
1985: Mattson M P; Spaziani E
Functional relations of crab molt-inhibiting hormone and neurohypophysial peptides.
Peptides 1985;6(4):635-40.
1985: Mattson M P; Spaziani E
Stress reduces hemolymph ecdysteroid levels in the crab: mediation by the eyestalks.
The Journal of experimental zoology 1985;234(2):319-23.

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