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Péter Mátyus

Research Profile

Chemicals & Drugs

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Physiology

Anatomy

Papillary Muscles

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Publications

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János Kósa; Dóra Kovács; Bernadett Balla; Evelin Horváth; Henrik Csaba Horváth; Péter Horváth; Péter Mátyus; Zsolt Nagy; Gábor Speer; István Takács; János Wölfling; Péter Lakatos
CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells.
Zoltán Zádori; Mahmoud Al-Khrasani; Serena B Brancati; Agnes Fehér; Lutz Hein; Erzsébet Lackó; Péter Mátyus; Viktória E Tóth; Klára Gyires
Imidazoline versus alpha2-adrenoceptors in the control of gastric motility in mice.
Miloš Ilić; Ewa Chabielska; Petra Dunkel; Janez Ilas; Péter Mátyus; Agnieszka Zakrzeska; Danijel Kikelj
Towards dual antithrombotic compounds - Balancing thrombin inhibitory and fibrinogen GPIIb/IIIa binding inhibitory activities of 2,3-dihydro-1,4-benzodioxine derivatives through regio- and stereoisomerism.

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All Publications

2013: János Kósa; Dóra Kovács; Bernadett Balla; Evelin Horváth; Henrik Csaba Horváth; Péter Horváth; Péter Mátyus; Zsolt Nagy; Gábor Speer; István Takács; János Wölfling; Péter Lakatos
CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells.
World journal of gastroenterology : WJG 2013;19(17):2621-8.
2013: Zoltán Zádori; Mahmoud Al-Khrasani; Serena B Brancati; Agnes Fehér; Lutz Hein; Erzsébet Lackó; Péter Mátyus; Viktória E Tóth; Klára Gyires
Imidazoline versus alpha2-adrenoceptors in the control of gastric motility in mice.
European journal of pharmacology 2013;705(1-3):61-7.
2013: Miloš Ilić; Ewa Chabielska; Petra Dunkel; Janez Ilas; Péter Mátyus; Agnieszka Zakrzeska; Danijel Kikelj
Towards dual antithrombotic compounds - Balancing thrombin inhibitory and fibrinogen GPIIb/IIIa binding inhibitory activities of 2,3-dihydro-1,4-benzodioxine derivatives through regio- and stereoisomerism.
European journal of medicinal chemistry 2013;62():329-40.
2012: Miloš Ilić; Andrej Boháč; Petra Dunkel; Janez Ilas; Sandra Liekens; Péter Mátyus; Danijel Kikelj
Novel 1,4-benzoxazine and 1,4-benzodioxine inhibitors of angiogenesis.
European journal of medicinal chemistry 2012;58():160-70.
2012: Petra Dunkel; Paul B Huleatt; Christina Ll Chai; Beáta Sperlágh; Péter Mátyus
Clinical utility of neuroprotective agents in neurodegenerative diseases: current status of drug development for Alzheimer's, Parkinson's and Huntington's diseases, and amyotrophic lateral sclerosis.
Expert opinion on investigational drugs 2012;21(9):1267-308.
2011: Petra Dunkel; Klára Gyires; Elias Maccioni; Balázs Balogh; Rita Meleddu; Péter Mátyus
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey.
Expert opinion on therapeutic patents 2011;21(9):1453-71.
2011: Anna Enzsöly; Hajnalka Györffy; Gábor Marics; Péter Mátyus; Zsuzsa Récsán; Jeanette Tóth; Miklós Tóth; Romána Zelkó; Zoltán Bori; Maria Luisa Di Paolo; Petra Dunkel; János Németh
Preliminary studies of the effects of vascular adhesion protein-1 inhibitors on experimental corneal neovascularization.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(7):1065-9.
2011: N Shujaa; Mahmoud Al-Khrasani; Zoltán Zádori; M Rossi; Péter Mátyus; J Németh; L Hein; Klára Gyires
α(2)-adrenoceptor agonist-induced inhibition of gastric motor activity is mediated by α(2A)-adrenoceptor subtype in the mouse.
Neurochemistry international 2011;58(6):708-13.
2010: Norbert Haider; Iris Hochholdinger; Péter Mátyus; Andrea Wobus
Synthesis of ortho-functionalized 4-aminomethylpyridazines as substrate-like semicarbazide-sensitive amine oxidase inhibitors.
Chemical & pharmaceutical bulletin 2010;58(7):964-70.
2009: Klára Gyires; Zoltán Zádori; Tamás L Török; Péter Mátyus
alpha(2)-Adrenoceptor subtypes-mediated physiological, pharmacological actions.
Neurochemistry international 2009;55(7):447-53.
2009: Balázs Balogh; András Szilágyi; Klára Gyires; David B Bylund; Péter Mátyus
Molecular modelling of subtypes (alpha(2A), alpha(2B) and alpha(2C)) of alpha(2)-adrenoceptors: a comparative study.
Neurochemistry international 2009;55(6):355-61.
2009: Gitte Van Baelen; Steven Hostyn; Liene Dhooghe; Pál Tapolcsányi; Péter Mátyus; Guy Lemière; Roger Dommisse; Marcel Kaiser; Reto Brun; Paul Cos; Louis Maes; György Hajós; Zsuzsanna Riedl; Ildikó Nagy; Bert U W Maes; Luc Pieters
Structure-activity relationship of antiparasitic and cytotoxic indoloquinoline alkaloids, and their tricyclic and bicyclic analogues.
Bioorganic & medicinal chemistry 2009;17(20):7209-17.
2009: Klára Gyires; Zoltán Zádori; N Shujaa; Mahmoud Al-Khrasani; B Pap; Miklós Mózes; Péter Mátyus
Pharmacological analysis of alpha(2)-adrenoceptor subtypes mediating analgesic, anti-inflammatory and gastroprotective actions.
Inflammopharmacology 2009;17(3):171-9.
2009: Attila Ványolós; András Simon; Gábor Tóth; László Polgár; Zoltán Kele; Anett Ilku; Péter Mátyus; Mária Báthori
C-29 ecdysteroids from Ajuga reptans var. reptans.
Journal of natural products 2009;72(5):929-32.
2008: Agnes Emma Daruházi; Lajos Szente; Balázs Balogh; Péter Mátyus; Szabolcs Béni; Mária Takács; András Gergely; Péter Horváth; Éva Szõke; Eva Lemberkovics
Utility of cyclodextrins in the formulation of genistein part 1. Preparation and physicochemical properties of genistein complexes with native cyclodextrins.
Journal of pharmaceutical and biomedical analysis 2008;48(3):636-40.
2008: Gloria Cristalli; Péter Mátyus; Peter Mohr; Giuseppe Ronsisvalle; Noël de Souza; Anna Tsantili-Kakoulidou
European medicinal chemistry education: the transformational accomplishments and challenges.
ChemMedChem 2008;3(4):561-3.
2008: Erzsébet Kató; Lóránt Lipták; Nashwan Shujaa; Péter Mátyus; Klára Gyires; András Z Rónai
alpha2B-adrenoceptor agonist ST-91 antagonizes beta2-adrenoceptor-mediated relaxation in rat mesenteric artery rings.
European journal of pharmacology 2008;580(3):361-5.
2008: P Dunkel; A Gelain; Daniela Barlocco; N Haider; Klára Gyires; B Sperlágh; Kálmán Magyar; E Maccioni; A Fadda; Péter Mátyus
Semicarbazide-sensitive amine oxidase/vascular adhesion protein 1: recent developments concerning substrates and inhibitors of a promising therapeutic target.
Current medicinal chemistry 2008;15(18):1827-39.
2007: Klára Gyires; Zoltán Zádori; Nashwan Shujaa; Renáta Minorics; George Falkay; Péter Mátyus
Analysis of the role of central and peripheral alpha2-adrenoceptor subtypes in gastric mucosal defense in the rat.
Neurochemistry international 2007;51(5):289-96.
2007: Balázs Balogh; Balázs Jójárt; Zsolt Wágner; Péter Kovács; Gáspár Máté; Klára Gyires; Zoltán Zádori; George Falkay; Arpád Márki; Béla Viskolcz; Péter Mátyus
3D QSAR models for alpha2a-adrenoceptor agonists.
Neurochemistry international 2007;51(5):268-76.
2007: Balázs Balogh; Csaba Hetényi; Miklós György Keseru; Péter Mátyus
Structure-based calculation of binding affinities of alpha 2A-adrenoceptor agonists.
ChemMedChem 2007;2(6):801-5.
2006: Angéla Benedek; Krisztina Móricz; Zsolt Jurányi; Gábor Gigler; György Lévay; László Gábor Hársing; Péter Mátyus; Gábor Szénási; Mihály Albert
Use of TTC staining for the evaluation of tissue injury in the early phases of reperfusion after focal cerebral ischemia in rats.
Brain research 2006;1116(1):159-65.
2005: Sabine van Miert; Steven Hostyn; Bert U W Maes; Kanyanga Cimanga; Reto Brun; Marcel Kaiser; Péter Mátyus; Roger Dommisse; Guy Lemière; Arnold Vlietinck; Luc Pieters
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound.
Journal of natural products 2005;68(5):674-7.
2004: Péter Mátyus; B Dajka-Halász; A Földi; N Haider; Daniela Barlocco; Kálmán Magyar
Semicarbazide-sensitive amine oxidase: current status and perspectives.
Current medicinal chemistry 2004;11(10):1285-98.
2004: Péter Mátyus; Ildikó Varga; Tivadar Rettegi; Antal Simay; Nikolett Kállay; László Károlyházy; Akos Kocsis; András Varró; István Pénzes; Julius Gy Papp
Novel antiarrhythmic compounds with combined class IB and class III mode of action.
Current medicinal chemistry 2004;11(1):61-9.
2004: András Varró; Péter Biliczki; Norbert Iost; Laszlo Virag; Ottó Hála; Péter Kovács; Péter Mátyus; Julius Gy Papp
Theoretical possibilities for the development of novel antiarrhythmic drugs.
Current medicinal chemistry 2004;11(1):1-11.
2003: Massud A S Anwair; László Károlyházy; Diána Szabó; Balázs Balogh; István Kövesdi; Veronika Harmat; Judit Krenyácz; Akos Gellért; Krisztina Takács-Novák; Péter Mátyus
Lipophilicity of aminopyridazinone regioisomers.
Journal of agricultural and food chemistry 2003;51(18):5262-70.
2003: László Károlyházy; Monica Freile; Massud N Anwair; Gyula Beke; Fernando Giannini; María V Castelli; Maximiliano Sortino; Juan Carlos Ribas; Susana Zacchino; Péter Mátyus; Ricardo D Enriz
Synthesis, in vitro/in vivo antifungal evaluation and structure-activity relationship study of 3(2H)-pyridazinones.
Arzneimittel-Forschung 2003;53(10):738-43.
2002: Gyula Beke; András Gergely; György Szász; Aletta Szentesi; József Nyitray; Orsolya Barabás; Veronika Harmath; Péter Mátyus
Synthesis and stereochemistry of dispiro substituted pyridazines: application of ellipticity-absorbance ratio spectra for proving enantiomeric relationship by HPLC-CD/UV detection.
Chirality 2002;14(5):365-71.
2002: M Opincariu; András Varró; Norbert Iost; Laszlo Virag; Ottó Hála; J Szolnoki; J Szécsi; Gábor Bogáts; P Szenohradszky; Péter Mátyus; Julius Gy Papp
The cellular electrophysiologic effect of a new amiodarone like antiarrhythmic drug GYKI 16638 in undiseased human ventricular muscle: comparison with sotalol and mexiletine.
Current medicinal chemistry 2002;9(1):41-6.
2001: Péter Mátyus
Cardiovascular and related agents.
Die Pharmazie 2001;56 Suppl 1():S50-5.
2001: Aletta Szentesi; András Gergely; Péter Horváth; S Mahó; Péter Mátyus; György Szász
Determination of circular dichroism and ultraviolet spectral parameters of norgestimate- and other Delta(4)-3-ketosteroid oxime isomers via normal phase HPLC method.
Current medicinal chemistry 2001;8(11):1341-7.
2001: László Károlyházy; G Horváth; Péter Mátyus
[A novel pyridazino-fused ring system: synthesis of pyridazino[3,4-b]diazepam].
Acta pharmaceutica Hungarica 2001;71(2):168-70.
2001: Stefania Villa; Daniela Barlocco; Giorgio Cignarella; G J Papp; B Baláti; János Takács; András Varró; A Borosy; K Keserû; Péter Mátyus
3,8-diazabicyclo--[3.2.1]-octane derivatives as analogues of ambasilide, a Class III antiarrhythmic agent.
European journal of medicinal chemistry 2001;36(6):495-506.
2001: Péter Mátyus
[Cardiovascular system research at the Institute of Drug Research].
Acta pharmaceutica Hungarica 2001;71(1):67-72.
2000: István Baczkó; NE El-Reyani; András Farkas; Laszlo Virag; Norbert Iost; István Leprán; Péter Mátyus; András Varró; Julius Gy Papp
Antiarrhythmic and electrophysiological effects of GYKI-16638, a novel N-(phenoxyalkyl)-N-phenylalkylamine, in rabbits.
European journal of pharmacology 2000;404(1-2):181-90.
2000: Péter Mátyus; T Rettegi; András Varró; Julius Gy Papp
New antiarrhythmic agents: a conceptually novel approach.
Medicinal research reviews 2000;20(4):294-303.
1999: István Kövesdi; M F Dominguez-Rodriguez; László Õrfi; G Náray-Szabó; András Varró; Julius Gy Papp; Péter Mátyus
Application of neural networks in structure-activity relationships.
Medicinal research reviews 1999;19(3):249-69.
1999: M Bidló-Iglóy; Péter Mátyus
Enantiomeric separation of optically active pyridazinone derivatives by chiral HPLC.
Journal of pharmaceutical and biomedical analysis 1999;19(3-4):487-90.
1998: Csaba Pankucsi; J Magyar; T Bányász; Péter Mátyus; P P Nánási
Novel antiarrhythmic agents with combined mode of action.
IDrugs : the investigational drugs journal 1998;1(5):554-60.
1998: Péter Mátyus; A P Borosy
[Three dimensional structure-activity relationships].
Acta pharmaceutica Hungarica 1998;68(1):33-8.
1997: Péter Mátyus; K Horváth
Alpha-adrenergic approach in the medical management of benign prostatic hyperplasia.
Medicinal research reviews 1997;17(6):523-35.
1997: Péter Mátyus; András Varró; Julius Gy Papp; H Wamhoff; I Varga; Laszlo Virag
Antiarrhythmic agents: current status and perspectives.
Medicinal research reviews 1997;17(5):427-51.
1997: Daniela Barlocco; Giorgio Cignarella; Francesca Fanelli; B Vitalis; Péter Mátyus; Pier G De Benedetti
Thienocycloheptapyridazines as new muscarinic agents.
Drug design and discovery 1997;14(4):273-90.
1994: Péter Mátyus; E Kasztreiner; E Diesler; A Behr; I Varga; J Kosáry; G Rabloczky; L Jaszlits
Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743.
Archiv der Pharmazie 1994;327(9):543-6.
1990: L Jaszlits; G Rabloczky; G Csókás; I Bódi; M Kürthy; EJ Horváth; A Kovács; Andrea Jednákovits; P Arányi; Péter Mátyus
GYKI-12 743, a novel antihypertensive compound with special alpha-adrenergic blocking profile.
Acta physiologica Hungarica 1990;75 Suppl():155-6.
1983: J Kosáry; G Szilágyi; Péter Mátyus; K Czakó; E Kasztreiner
[Potential CNS depressing agents containing a pyridazine ring. Studies in the field of compounds containing a pyridazine ring (1)].
Acta pharmaceutica Hungarica 1983;53(3):106-14.
1981: Z Huszti; G Szilágyi; Péter Mátyus; E Kasztreiner
Influence on turnover and level of hypothalamic noradrenaline by a new antihypertensive agent (GYKI 11679).
Journal of neurochemistry 1981;37(5):1272-81.
1979: Péter Mátyus; I Schäfer; E Szondy
[The diuretic effect of imidazo(1,2-a)pyridines].
Acta pharmaceutica Hungarica 1979;49(5):234-40.